Degotte, G., Pirotte, B., Frederich, M., & Francotte, P. (in press). Polyhydroxybenzoic acid derivatives as potential new antimalarial agents. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft.
Peer reviewed
With more than 200 million cases and 400,000 related deaths, malaria remains one of the deadliest infectious diseases of 2021. Unfortunately, despite the availability of efficient treatments, we have ...
Tomani, J. C. D., Bonnet, O., Nyirimigabo, A., Deschamps, W., Tchinda, A. T., Jansen, O., Ledoux, A., Mukazayire, M.-J., Vanhamme, L., Frederich, M., Muganga, R., & Souopgui, J. (2021). In Vitro Antiplasmodial and Cytotoxic Activities of Compounds from the Roots of Eriosema montanum Baker f. (Fabaceae). Molecules, 26(9), 2795.
Peer reviewed (verified by ORBi)
Malaria remains one of the leading causes of death in sub-Saharan Africa, ranked in thetop three infectious diseases in the world. Plants of theEriosemagenus have been reported to beused for the treatment of ...
Kowa, T., Jansen, O., Ledoux, A., Coelho Cristino Mamede, L. C., Wabo, H., Tchinda Tiabou, A., Genta-Jouve, G., & Frederich, M. (2021, May 06). Bioassay-guided isolation of vilasinin–type limonoids and phenyl alkene from the leaves of Trichilia gilgiana and their antiplasmodial activities. Natural Product Research.
Peer reviewed (verified by ORBi)
Degotte, G., Pirotte, B., Francotte, P., & Frederich, M. (2021, March). Overview of natural antiplasmodials from the last decade to inspire medicinal chemistry. Current Medicinal Chemistry.
Peer reviewed (verified by ORBi)
Background: Despite the major advances in the fight against this parasitic disease, malaria remains a major cause of concerns in 2020. This infection, mainly due to Plasmodium falciparum, causes every year ...
Toukam, P. D., Kom, C. W., Tchamgoué, A. D., Doupno, E. A. K., Lame, Y., Yamthé, L. R. T., Kopa Kowa, T., Tchinda, A. T., Frederich, M., Mbafor, J. T., & De Théodore Atchadé, A. (2021, February 24). A new isoquinoline and ceramide from the stem barks of Discoglypremna caloneura (Pax) Prain (Euphorbiaceae) with antiproteinase and cytotoxic activities. Natural Product Research, 1-9.
Peer reviewed (verified by ORBi)
Two new compounds, an isoquinoline (1) and caloneuramide (2), a ceramide were isolated from the stem bark of Discoglypremna caloneura together with seven known compounds namely aurantiamide acetate (3 ...
Kagisha, V., Marini Djang'Eing'A, R., Muganga, R., Bonnet, O., Tchinda, A. T., Jansen, O., Tomani, J. C., Njakarinala, R., Ledoux, A., Nyirimigabo, A., & Frederich, M. (2021). Pentas longiflora Oliv. (Rubiaceae), a plant used in the treatment of Pityriasis Versicolor in Rwanda: Chemical composition and standardization of leaves and roots. Fitoterapia, 153, 104974.
Peer reviewed (verified by ORBi)
In Rwanda, the roots of Pentas longiflora Oliv. (Rubiaceae) have been used for a long time to treat Pityriasis versicolor. However, many people reported the use of leaves instead of roots. This research was ...
Ma'mag, L. K., Zintchem, A. A. A., Théodora, K. K., Théodore, A. A. D., lauve, T. Y., Frederich, M., Bikobo, D. S. N., & Pegnyemb, D. E. (2021). Antiplasmodial and antileishmanial inhibitory activity of triterpenes and steroidal alkaloid from the leaves of Funtumia elastica (Preuss) Stapf (Apocynaceae). Fitoterapia, 104869.
Peer reviewed (verified by ORBi)
The phytochemical study of leaves of Funtumia elastica led to the isolation of three undescribed ursane derivatives, funtumic acids A, B and C (1–3), as well as one steroidal alkaloid, elasticine (4) and five ...
Nea, F., Bitchi, M. B., Genva, M., Ledoux, A., Tchinda Tiabou, A., Damblon, C., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (2021). Phytochemical investigation and biological activities of Lantana rhodesiensis. Molecules, 26(4), 846.
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Lantana rhodesiensis Moldenke is a plant widely used to treat diseases, such as rheumatism, diabetes, and malaria in traditional medicine. To better understand the traditional uses of this plant, a ...
Saive, M.* , Genva, M.* , Istasse, T., Frederich, M., Maes, C., & Fauconnier, M.-L. (2020). Identification of a proanthocyanidin from Litchi chinensis Sonn. root with anti-tyrosinase and antioxidant activity. Biomolecules, 10(9), 1347.
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This work follows an ethnobotanical study that took place in the island of Mayotte (France), which pointed out the potential properties of Litchi chinensis Sonn. roots when used to enhance skin health and ...
* These authors have contributed equally to this work.
Kagisha, V., Frederich, M., Ledoux, A., Jansen, O., NYIRIMIGABO, A., MUGANGA, R., & Marini Djang'Eing'A, R. (2020). HPLC-UV Method for Standardization of Neorautanenia mitis, an African Plant Used in an Anti-Scabies Ointment. Revista Brasileira de Farmacognosia, 30(4), 582-587.
Peer reviewed (verified by ORBi)
An HPLC-UV method for standardization of the methanol-soluble extracts from tubers of Neorautanenia mitis (A.Rich.) Verdc., Fabaceae, harvested during different periods and from different sites, is described ...