[en] ETHNOPHARMACOLOGICAL RELEVANCE: Indigofera is the third-largest genus in the family of Fabaceae, with approximately 750 species. It is distributed across all tropical regions. Indigofera species are widely employed in traditional medicine all around the world, against many ailments. Thus, based on these medicinal properties, various investigations have been undertaken in order to appraise the pharmacological activities and the chemical composition of these species. A recent paper provides a summary of the phytochemistry and pharmacology of the genus Indigofera. Consequently, this review is a continuation of this previous study by updating some data and adding information about the phylogeny and traditional uses of the genus. AIM OF THE STUDY: To provide an overview of the phylogeny, traditional uses, phytochemistry, pharmacology and toxicity of the genus Indigofera, and to identify the remaining gaps and thus supply a basis for further investigations. MATERIALS AND METHODS: A review of the literature was performed by consulting scientific databases such as 'ScienceDirect', 'PubMed', 'Google Scholar' and 'SpringerLink' and using the keyword Indigofera. RESULTS: Over 60 Indigofera species are reported in traditional medicine. The uses depend on the country and the species, but similarities have been noticed. Indeed, treatments of gastrointestinal disorders, inflammatory conditions and pain, skin ailments, and respiratory and infectious diseases are recurring. Phytochemical studies have led to the identification of more than 200 compounds, notably flavonoids and terpenoids. Many pharmacological activities have been demonstrated, particularly antimicrobial, cytotoxic and anti-inflammatory activities, and thus allowed to assert most of the traditional uses of the genus. Some active compounds have been isolated and have shown remarkable therapeutic potential, like the alkaloid indirubin, which is currently being clinically trialed. CONCLUSIONS: The data on the genus Indigofera are extensive, but gaps still remain. Indeed, some promising species have not been assessed for their phytochemistry and/or pharmacology and thus remain unexplored. Moreover, relatively few active compounds have been isolated and tested for their biological activity, and studies to explain their mechanism of action are nearly inexistent. Furthermore, some pharmacological studies have inappropriate methodologies that make the results difficult to interpret. Consequently, further in-depth and relevant research is required to supplement the knowledge on this wide-ranging genus and to confirm its reported therapeutic potential.
Research center :
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Gerometta, Elise
Grondin, Isabelle
Smadja, Jacqueline
Frederich, Michel ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Gauvin-Bialecki, Anne
Language :
English
Title :
A review of traditional uses, phytochemistry and pharmacology of the genus Indigofera.
Publication date :
2020
Journal title :
Journal of Ethnopharmacology
ISSN :
0378-8741
eISSN :
1872-7573
Publisher :
Elsevier, Switzerland
Volume :
253
Pages :
112608
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2020 Elsevier B.V. All rights reserved.
Abdel Moneim, A.E., Indigofera oblongifolia prevents lead acetate-induced hepatotoxicity, oxidative stress, fibrosis and apoptosis in rats. PloS One, 11, 2016, e0158965, 10.1371/journal.pone.0158965.
Abe, R., Ohtani, K., An ethnobotanical study of medicinal plants and traditional therapies on Batan Island, the Philippines. J. Ethnopharmacol. 145 (2013), 554–565, 10.1016/j.jep.2012.11.029.
Abraham, P., Arul, V., Philip, S., Padmakeerthiga, B., Madhavan, N.R., Sethupathy, S., Effect of Indigofera aspalathoides leaf extract on hepatic xenobiotic enzymes activity in hamster with DMBA induced oral cancer. Int. J. Drug Dev. Res. 2 (2010), 476–481.
Abubakar, M.S., Musa, A.M., Ahmed, A., Hussaini, I.M., The perception and practice of traditional medicine in the treatment of cancers and inflammations by the Hausa and Fulani tribes of Northern Nigeria. J. Ethnopharmacol. 111 (2007), 625–629, 10.1016/j.jep.2007.01.011.
Adamu, H.M., Abayeh, O.J., Agho, M.O., Abdullahi, A.L., Uba, A., Dukku, H.U., Wufem, B.M., An ethnobotanical survey of Bauchi State herbal plants and their antimicrobial activity. J. Ethnopharmacol. 99 (2005), 1–4, 10.1016/j.jep.2004.12.025.
Adamu, M., Naidoo, V., Eloff, J.N., Some southern African plant species used to treat helminth infections in ethnoveterinary medicine have excellent antifungal activities. BMC Compl. Alternative Med. 12 (2012), 1–7, 10.1186/1472-6882-12-213.
Agarwal, A., Sharma, V., PUB082 Role of isolated flavonoid from Indigofera tinctoria in n-nitrosopyrrolidine induced biochemical changes related to lung cancer. J. Thorac. Oncol., 12, 2017, S1495, 10.1016/j.jtho.2016.11.2052.
Agra, M.F., Baracho, G.S., Nurit, K., Basílio, I.J.L.D., Coelho, V.P.M., Medicinal and poisonous diversity of the flora of “Cariri Paraibano”, Brazil. J. Ethnopharmacol. 111 (2007), 383–395, 10.1016/j.jep.2006.12.007.
Agyare, C., Obiri, D.D., Boakye, Y.D., Osafo, N., Anti-inflammatory and analgesic activities of african medicinal plants. Medicinal Plant Research in Africa, 2013, Elsevier, 725–752, 10.1016/B978-0-12-405927-6.00019-9.
Ahmad Jan, H., Wali, S., Ahmad, L., Jan, S., Ahmad, N., Ullah, N., Ethnomedicinal survey of medicinal plants of Chinglai valley, Buner district, Pakistan. Eur. J. Integr. Med. 13 (2017), 64–74, 10.1016/j.eujim.2017.06.007.
Ahmadu, A.A., Onanuga, A., Ebeshi, B.U., Isolation of antibacterial flavonoids from the aerial parts of Indigofera secundiflora. Phcog. J. 3 (2011), 25–28, 10.5530/pj.2011.19.5.
Ajao, A.A., Sibiya, N.P., Moteetee, A.N., Sexual prowess from nature: a systematic review of medicinal plants used as aphrodisiacs and sexual dysfunction in sub-Saharan Africa. South Afr. J. Bot., 2018, 10.1016/j.sajb.2018.08.011.
Al-Asmari, A., Manthiri, R.A., Abdo, N., Al-Duaiji, F.A., Khan, H.A., Saudi medicinal plants for the treatment of scorpion sting envenomation. Saudi J. Biol. Sci. 24 (2017), 1204–1211, 10.1016/j.sjbs.2016.10.010.
Al-Fatimi, M., Wurster, M., Schröder, G., Lindequist, U., Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen. J. Ethnopharmacol. 111 (2007), 657–666, 10.1016/j.jep.2007.01.018.
Al-Quraishy, S., Dkhil, M., Ibrahim, S., Abdel Moneim, A., Neuroprotective potential of Indigofera oblongifolia leaf methanolic extract against lead acetate-induced neurotoxicity. Neural Regen. Res., 11, 2016, 1797, 10.4103/1673-5374.194749.
Alamgeer, Uttra, A.M., Ahsan, H., Hasan, U.H., Chaudhary, M.A., Traditional medicines of plant origin used for the treatment of inflammatory disorders in Pakistan: a review. J. Tradit. Chin. Med. 38 (2018), 636–656, 10.1016/S0254-6272(18)30897-5.
Ali, N.A.A., Jülich, W.-D., Kusnick, C., Lindequist, U., Screening of Yemeni medicinal plants for antibacterial and cytotoxic activities. J. Ethnopharmacol. 74 (2001), 173–179, 10.1016/S0378-8741(00)00364-0.
Amjad, M.S., Arshad, M., Ethnobotanical inventory and medicinal uses of some important woody plant species of Kotli, Azad Kashmir, Pakistan. Asian Pac. J. Trop. Biomed. 4 (2014), 952–958, 10.12980/APJTB.4.201414B381.
Amjad, M.S., Arshad, M., Qureshi, R., Ethnobotanical inventory and folk uses of indigenous plants from Pir Nasoora National Park, Azad Jammu and Kashmir. Asian Pac. J. Trop. Biomed. 5 (2015), 234–241, 10.1016/S2221-1691(15)30011-3.
Amjad, M.S., Arshad, M., Saboor, A., Page, S., Chaudhari, S.K., Ethnobotanical profiling of the medicinal flora of Kotli, Azad Jammu and Kashmir, Pakistan: empirical reflections on multinomial logit specifications. Asian Pac. J. Trop. Med. 10 (2017), 503–514, 10.1016/j.apjtm.2017.05.008.
Amusan, O.O.G., Dlamini, P.S., Msonthi, J.D., Makhubu, L.P., Some herbal remedies from Manzini region of Swaziland. J. Ethnopharmacol. 79 (2002), 109–112, 10.1016/S0378-8741(01)00381-6.
Andreazza, N.L., de Lourenço, C.C., Stefanello, M.É.A., Atvars, T.D.Z., Salvador, M.J., Photodynamic antimicrobial effects of bis-indole alkaloid indigo from Indigofera truxillensis Kunth (Leguminosae). Laser Med. Sci. 30 (2015), 1315–1324, 10.1007/s10103-015-1735-4.
Arbab, A.H., Parvez, M.K., Al-Dosari, M.S., Al-Rehaily, A.J., In vitro evaluation of novel antiviral activities of 60 medicinal plants extracts against hepatitis B virus. Exp. Therapeut. Med. 14 (2017), 626–634, 10.3892/etm.2017.4530.
Arriaga, A.M.C., Lemos, T.L.G., Santiago, G.M.P., Andrade-Neto, M., Braga, M.A., de Almeida, M.C.S., Gomes, T.B.M., Rodrigues, F.E.A., Vasconcelos, J.N., Alves, P.B., Chemical composition and antioxidant activity of Indigofera suffruticosa. Chem. Nat. Compd. 49 (2013), 150–151, 10.1007/s10600-013-0539-7.
Asase, A., Oppong-Mensah, G., Traditional antimalarial phytotherapy remedies in herbal markets in southern Ghana. J. Ethnopharmacol. 126 (2009), 492–499, 10.1016/j.jep.2009.09.008.
Asase, A., Oteng-Yeboah, A.A., Odamtten, G.T., Simmonds, M.S.J., Ethnobotanical study of some Ghanaian anti-malarial plants. J. Ethnopharmacol. 99 (2005), 273–279, 10.1016/j.jep.2005.02.020.
Asuntha, G., Prasannaraju, Y., Prasad, K.V.S.R.G., Effect of ethanol extract of Indigofera tinctoria Linn (Fabaceae) on lihtium/pilocarpine-induced status epilepticus and oxidative stress in wistar rats. Trop. J. Pharmaceut. Res. 9 (2010), 149–156.
Aziz, M.A., Khan, A.H., Adnan, M., Izatullah, I., Traditional uses of medicinal plants reported by the indigenous communities and local herbal practitioners of Bajaur Agency, Federally Administrated Tribal Areas, Pakistan. J. Ethnopharmacol. 198 (2017), 268–281, 10.1016/j.jep.2017.01.024.
Balamurugan, G., Selvarajan, S., Preliminary phytochemical screening and anthelmintic activity of Indigofera tinctoria Linn. Int. J. Drug Dev. Res. 4 (2009), 157–160.
Balasubramanian, R., Narayanan, M., Kedalgovindaram, L., Devarakonda Rama, K., Cytotoxic activity of flavone glycoside from the stem of Indigofera aspalathoides Vahl. J. Nat. Med. 61 (2006), 80–83, 10.1007/s11418-006-0026-6.
Barkatullah Ibrar, M., Rauf, A., Ben Hadda, T., Mubarak, M.S., Patel, S., Quantitative ethnobotanical survey of medicinal flora thriving in Malakand Pass hills, Khyber Pakhtunkhwa, Pakistan. J. Ethnopharmacol. 169 (2015), 335–346, 10.1016/j.jep.2015.04.052.
Becker, T., Pasteels, J., Weigel, C., Dahse, H.-M., Voigt, K., Boland, W., A tale of four kingdoms – isoxazolin-5-one- and 3-nitropropanoic acid-derived natural products. Nat. Prod. Rep. 34 (2017), 343–360, 10.1039/C6NP00122J.
Bello, O.M., Zaki, A.A., Khan, S.I., Fasinu, P.S., Ali, Z., Khan, I.A., Usman, L.A., Oguntoye, O.S., Assessment of selected medicinal plants indigenous to West Africa for antiprotozoal activity. South Afr. J. Bot. 113 (2017), 200–211, 10.1016/j.sajb.2017.08.002.
Bello, O.M., Ibitoye, T., Adetunji, C., Assessing antimicrobial agents of Nigeria flora. J. King Saud Univ. Sci., 2018, 10.1016/j.jksus.2018.04.017.
Bezerra dos Santos, A.T., Araujo, T.F. da S., Nascimento da Silva, L.C., Silva, C.B. da, Oliveira, A.F.M. de, Araujo, J.M., Correia, M.T., dos, S., Lima, V.L. de M., Organic extracts from Indigofera suffruticosa leaves have antimicrobial and synergic actions with erythromycin against Staphylococcus aureus. Front. Microbiol., 6, 2015, 10.3389/fmicb.2015.00013.
Bhagavan, N.B., Arunachalam, S., Dhasarathan, P., Kannan, N.D., Evaluation of anti inflammatory activity of Indigofera aspalathoides Vahl in Swiss albino mice. J. Pharm. Res. 6 (2013), 350–354, 10.1016/j.jopr.2013.02.018.
Bhaskar, B.V., Mohan, A.R., Babu, T.M.C., Rajesh, S.S., Bhuvaneswar, C., Sivaraman, T., Gunasekar, D., Rajendra, W., Antibacterial efficacy of fractions and compounds from Indigofera barberi: identification of DNA gyrase B inhibitors through pharmacophore based virtual screening. Process Biochem. 51 (2016), 2208–2221, 10.1016/j.procbio.2016.08.031.
Bieski, I.G.C., Leonti, M., Arnason, J.T., Ferrier, J., Rapinski, M., Violante, I.M.P., Balogun, S.O., Pereira, J.F.C.A., Figueiredo, R. de C.F., Lopes, C.R.A.S., da Silva, D.R., Pacini, A., Albuquerque, U.P., Martins, D.T. de O., Ethnobotanical study of medicinal plants by population of valley of Juruena region, Legal Amazon, Mato Grosso, Brazil. J. Ethnopharmacol. 173 (2015), 383–423, 10.1016/j.jep.2015.07.025.
Birru, E., Evaluation of the effect of crude leaves extract of Indigofera spicata Forssk. (Fabaceae) on blood glucose level of normoglycemic, oral glucose loaded and alloxan induced diabetic rodents. Value Health, 18, 2015, A704, 10.1016/j.jval.2015.09.2641.
Birru, E.M., Abdelwuhab, M., Shewamene, Z., Effect of hydroalcoholic leaves extract of Indigofera spicata Forssk. on blood glucose level of normal, glucose loaded and diabetic rodents. BMC Compl. Alternative Med., 15, 2015, 10.1186/s12906-015-0852-8.
Birru, E.M., Asrie, A.B., Adinew, G.M., Tsegaw, A., Antidiarrhoeal activity of crude methanolic root extract of Idigofera spicata Forssk.(Fabaceae). BMC Compl. Alternative Med., 16, 2016, 10.1186/s12906-016-1252-4.
Birru, E.M., Geta, M., Gurmu, A.E., Antiplasmodial activity of Indigofera spicata root extract against Plasmodium berghei infection in mice. Malar. J., 16, 2017, 10.1186/s12936-017-1853-5.
Boothapandi, M., Ravichandran, R., Antiproliferative activity of chrysin (5, 7-dihydroxyflavone) from Indigofera tinctoria on human epidermoid carcinoma (A431) cells. Eur. J. Integr. Med. 24 (2018), 71–78, 10.1016/j.eujim.2018.10.015.
Bruschi, P., Morganti, M., Mancini, M., Signorini, M.A., Traditional healers and laypeople: a qualitative and quantitative approach to local knowledge on medicinal plants in Muda (Mozambique). J. Ethnopharmacol. 138 (2011), 543–563, 10.1016/j.jep.2011.09.055.
Bunalema, L., Obakiro, S., Tabuti, J.R.S., Waako, P., Knowledge on plants used traditionally in the treatment of tuberculosis in Uganda. J. Ethnopharmacol. 151 (2014), 999–1004, 10.1016/j.jep.2013.12.020.
Burdock, G.A., Carabin, I.G., Soni, M.G., Safety assessment of b-nitropropionic acid: a monograph in support of an acceptable daily intake in humans. Food Chem. 75 (2001), 1–27.
Calvo, T.R., Cardoso, C.R.P., da Silva Moura, A.C., dos Santos, L.C., Colus, I.M.S., Vilegas, W., Varanda, E.A., Mutagenic activity of Indigofera truxillensis and I. suffruticosa aerial parts. Evid. Base Compl. Alternative Med. 2011 (2011), 1–9, 10.1093/ecam/nep123.
Campos, J.K.L., Araújo, T.F. da S., Brito, T.G. da S., Silva, A.P.S. da, Cunha, R.X. da, Martins, M.B., Silva, N.H., dos Santos, B.S., da Silva, C.A., da Lima, V.L. de M., Indigofera suffruticosa Mill. (Anil): plant profile, phytochemistry, and pharmacology review. Adv. Pharmacol. Sci. 2018 (2018), 1–6, 10.1155/2018/8168526.
Catarino, L., Havik, P.J., Romeiras, M.M., Medicinal plants of Guinea-Bissau: therapeutic applications, ethnic diversity and knowledge transfer. J. Ethnopharmacol. 183 (2016), 71–94, 10.1016/j.jep.2016.02.032.
Chagnon, M., Inventaire pharmacologique general des plantes medicinales rwandaises. J. Ethnopharmacol. 12 (1984), 239–251, 10.1016/0378-8741(84)90053-9.
Chakrabarti, R., Damarla, R.K.B., Mullangi, R., Sharma, V.M., Vikramadithyan, R.K., Rajagopalan, R., Insulin sensitizing property of Indigofera mysorensis extract. J. Ethnopharmacol. 105 (2006), 102–106, 10.1016/j.jep.2005.10.010.
Chan, L., Gosangari, S., Watkin, K., Cunningham, B., Label-free imaging of cancer cells using photonic crystal biosensors and application to cytotoxicity screening of a natural compound library. Sensor. Actuator. B Chem. 132 (2008), 418–425, 10.1016/j.snb.2007.10.027.
Chapuis, J.-C., Sordat, B., Hostettmann, K., Screening for cytotoxic activity of plants used in traditional medicine. J. Ethnopharmacol. 23 (1988), 273–284, 10.1016/0378-8741(88)90006-2.
Chellappandian, M., Mutheeswaran, S., Pandikumar, P., Duraipandiyan, V., Ignacimuthu, S., Quantitative ethnobotany of traditional Siddha medical practitioners from Radhapuram taluk of Tirunelveli district, Tamil Nadu, India. J. Ethnopharmacol. 143 (2012), 540–547, 10.1016/j.jep.2012.07.014.
Chen, C.-C., Liu, C.-S., Li, C.-C., Tsai, C.-W., Yao, H.-T., Liu, T.-C., Chen, H.-W., Chen, P.-Y., Wu, Y.-L., Lii, C.-K., Liu, K.-L., Indigofera suffruticosa Mill extracts up-regulate the expression of the π class of glutathione S-transferase and NAD(P)H: quinone oxidoreductase 1 in rat Clone 9 liver cells. Food Chem. Toxicol. 59 (2013), 610–617, 10.1016/j.fct.2013.06.042.
Chen, T.-Y., Sun, H.-L., Yao, H.-T., Lii, C.-K., Chen, H.-W., Chen, P.-Y., Li, C.-C., Liu, K.-L., Suppressive effects of Indigofera suffruticosa Mill extracts on lipopolysaccharide-induced inflammatory responses in murine RAW 264.7 macrophages. Food Chem. Toxicol. 55 (2013), 257–264, 10.1016/j.fct.2012.12.056.
Cheng, H.-M., Wu, Y.-C., Wang, Q., Song, M., Wu, J., Chen, D., Li, K., Wadman, E., Kao, S.-T., Li, T.-C., Leon, F., Hayden, K., Brodmerkel, C., Chris Huang, C., Clinical efficacy and IL-17 targeting mechanism of Indigo naturalis as a topical agent in moderate psoriasis. BMC Compl. Alternative Med., 17, 2017, 10.1186/s12906-017-1947-1.
Chhabra, S.C., Mahunnah, R.L.A., Mshiu, E.N., Plants used in traditional medicine in Eastern Tanzania. IV. Angiosperms (Mimosaceae to Papilionaceae). J. Ethnopharmacol. 29 (1990), 295–323, 10.1016/0378-8741(90)90041-Q.
Chifundera, K., Contribution to the inventory of medicinal plants from the Bushi area, South Kivu Province, Democratic Republic of Congo. Fitoterapia 72 (2001), 351–368, 10.1016/S0367-326X(00)00294-X.
Chinsembu, K.C., Ethnobotanical study of medicinal flora utilised by traditional healers in the management of sexually transmitted infections in Sesheke District, Western Province, Zambia. Rev. Bras. Farmacogn. 26 (2016), 268–274, 10.1016/j.bjp.2015.07.030.
Chinsembu, K.C., Syakalima, M., Semenya, S.S., Ethnomedicinal plants used by traditional healers in the management of HIV/AIDS opportunistic diseases in Lusaka, Zambia. South Afr. J. Bot., 2018, 10.1016/j.sajb.2018.09.007.
Christina, A.J., Alwin Jose, M., Heison Robert, S.J., Kothai, R., Chidambaranathan, N., Muthumani, P., Effect of Indigofera aspalathoides against Dalton's ascitic lymphoma. Fitoterapia 74 (2003), 280–283, 10.1016/S0367-326X(03)00038-8.
Cock, I.E., Selesho, M.I., Van Vuuren, S.F., A review of the traditional use of southern African medicinal plants for the treatment of selected parasite infections affecting humans. J. Ethnopharmacol. 220 (2018), 250–264, 10.1016/j.jep.2018.04.001.
Coe, F.G., Rama midwifery in eastern Nicaragua. J. Ethnopharmacol. 117 (2008), 136–157, 10.1016/j.jep.2008.01.027.
Coe, F.G., Anderson, G.J., Snakebite ethnopharmacopoeia of eastern Nicaragua. J. Ethnopharmacol. 96 (2005), 303–323, 10.1016/j.jep.2004.09.026.
Coelho-Ferreira, M., Medicinal knowledge and plant utilization in an Amazonian coastal community of Marudá, Pará State (Brazil). J. Ethnopharmacol. 126 (2009), 159–175, 10.1016/j.jep.2009.07.016.
Cola-Miranda, M., Barbastefano, V., Hiruma-Lima, C.A., Calvo, T.R., Vilegas, W., Brito, A.R.M.S., Antiulcerogenic activity of Indigofera truxillensis Kunth. Biota Neotropica, 6, 2006, 10.1590/S1676-06032006000300004.
Cooke, A., The toxic constituent of Indigofera endecaphylla. 1954, 114–120.
Cope, R., Ossedryver, S., Poisonous plants of Australia and New Zealand. Veterinary Toxicology, 2018, Elsevier, 911–934, 10.1016/B978-0-12-811410-0.00063-5.
Cos, P., Hermans, N., De Bruyne, T., Apers, S., Sindambiwe, J.B., Vanden Berghe, D., Pieters, L., Vlietinck, A.J., Further evaluation of Rwandan medicinal plant extracts for their antimicrobial and antiviral activities. J. Ethnopharmacol. 79 (2002), 155–163, 10.1016/S0378-8741(01)00362-2.
Cos, P., Hermans, N., De Bruyne, T., Apers, S., Sindambiwe, J.B., Witvrouw, M., De Clercq, E., Vanden Berghe, D., Pieters, L., Vlietinck, A.J., Antiviral activity of Rwandan medicinal plants against human immunodeficiency virus type-1 (HIV-1). Phytomedicine 9 (2002), 62–68, 10.1078/0944-7113-00083.
Cos, P., Hermans, N., Van Poel, B., De Bruyne, T., Apers, S., Sindambiwe, J.B., Vanden Berghe, D., Pieters, L., Vlietinck, A.J., Complement modulating activity of Rwandan medicinal plants. Phytomedicine 9 (2002), 56–61, 10.1078/0944-7113-00085.
Cragg, G.M., Newman, D.J., Plants as a source of anti-cancer agents. J. Ethnopharmacol. 100 (2005), 72–79, 10.1016/j.jep.2005.05.011.
da Silva, I.B., Lima, I.R., Santana, M.A.N., Leite, R.M.P., Leite, S.P., Indigofera suffruticosa Mill (Fabaceae): hepatic responses in mice bearing sarcoma 180. Int. J. Morphol. 32 (2014), 1228–1233, 10.4067/S0717-95022014000400017.
Dahot, M.U., Antibacterial and antifungal activity of small protein of Indigofera oblongifolia leaves. J. Ethnopharmacol. 64 (1999), 277–282, 10.1016/S0378-8741(98)00136-6.
de Albuquerque, U.P., de Medeiros, P.M., de Almeida, A.L.S., Monteiro, J.M., de Freitas Lins Neto, E.M., de Melo, J.G., dos Santos, J.P., Medicinal plants of the caatinga (semi-arid) vegetation of NE Brazil: a quantitative approach. J. Ethnopharmacol. 114 (2007), 325–354, 10.1016/j.jep.2007.08.017.
de, A., Carli, C.B., Quilles, M.B., Maia, D.C.G., Lopes, F.C.M., Santos, R., Pavan, F.R., Fujimura Leite, C.Q., Calvo, T.R., Vilegas, W., Carlos, I.Z., Antimycobacterial activity of Indigofera suffruticosa with activation potential of the innate immune system. Pharmaceut. Biol. 48 (2010), 878–882, 10.3109/13880200903303471.
De Montellano, B.R.O., Browner, C.H., Chemical bases for medicinal plant use in Oaxaca, Mexico. J. Ethnopharmacol. 13 (1985), 57–88, 10.1016/0378-8741(85)90062-5.
Deshpande, P., Dhodi, J., Gawali, N., Kothavade, P., Chowdhury, A., Juvekar, A., Indigofera cordifolia seeds attenuate the oxidative stress and inflammation associated with streptozotocin induced type 2 diabetes mellitus. Cytokine, 70, 2014, 37, 10.1016/j.cyto.2014.07.044.
Devi Prasad, A., Chaturvedi, V., Kumar, Jk, Phytochemical screening of five medicinal legumes and their evaluation for in vitro anti-tubercular activity. AYU Int. Q. J. Res. Ayurveda, 35, 2014, 98, 10.4103/0974-8520.141952.
Dey, A., Gorai, P., Mukherjee, A., Dhan, R., Modak, B.K., Ethnobiological treatments of neurological conditions in the Chota Nagpur plateau, India. J. Ethnopharmacol. 198 (2017), 33–44, 10.1016/j.jep.2016.12.040.
Dkhil, M.A., Lubbad, M., Al-Shaebi, E., Delic, D., Al-Quraishy, S., The antiplasmodial and spleen protective role of crude Indigofera oblongifolia leaf extract traditionally used in the treatment of malaria in Saudi Arabia. Drug Des. Dev. Ther., 2015, 6235, 10.2147/DDDT.S94673.
Dkhil, M.A., Moneim, A.E.A., Al-Quraishy, S., Indigofera oblongifolia ameliorates lead acetate-induced testicular oxidative damage and apoptosis in a rat model. Biol. Trace Elem. Res. 173 (2016), 354–361, 10.1007/s12011-016-0689-0.
Dominguez, X., Martinez, C., Calero, A., Dominguez, X. Jr., Hinojosa, M., Zamudio, A., Louisfieserone, an unusual flavanone derivative from Indigofera suffruticosa Mill. Tetrahedron Lett. 5 (1978), 429–432.
Dorla, E., Grondin, I., Hue, T., Clerc, P., Dumas, S., Gauvin-Bialecki, A., Laurent, P., Traditional uses, antimicrobial and acaricidal activities of 20 plants selected among Reunion Island's flora. South Afr. J. Bot., 2018, 10.1016/j.sajb.2018.04.014.
Dutt, H.C., Bhagat, N., Pandita, S., Oral traditional knowledge on medicinal plants in jeopardy among Gaddi shepherds in hills of northwestern Himalaya, J&K, India. J. Ethnopharmacol. 168 (2015), 337–348, 10.1016/j.jep.2015.03.076.
Dzoyem, J.P., McGaw, L.J., Eloff, J.N., In vitro antibacterial, antioxidant and cytotoxic activity of acetone leaf extracts of nine under-investigated Fabaceae tree species leads to potentially useful extracts in animal health and productivity. BMC Compl. Alternative Med., 14, 2014, 10.1186/1472-6882-14-147.
Elegami, A.A., Almagboul, A.Z., Omer, M.E.A., El Tohami, M.S., Sudanese plants used in folkloric medicine: screening for antibacterial activity. Part X. Fitoterapia 72 (2001), 810–817.
Elmi, A., Spina, R., Abdoul-Latif, F., Yagi, S., Fontanay, S., Risler, A., Duval, R.E., Laurain-Mattar, D., Rapid screening for bioactive natural compounds in Indigofera caerulea Rox fruits. Ind. Crop. Prod. 125 (2018), 123–130, 10.1016/j.indcrop.2018.08.089.
Fogaça, M.V., Cândido-Bacani, P. de M., Benicio, L.M., Zapata, L.M., Cardoso, P. de F., de Oliveira, M.T., Calvo, T.R., Varanda, E.A., Vilegas, W., de Syllos Cólus, I.M., Effects of indirubin and isatin on cell viability, mutagenicity, genotoxicity and BAX/ERCC1 gene expression. Pharmaceut. Biol., 55, 2017, 10.1080/13880209.2017.1354387 2005–2014.
Frei, B., Baltisberger, M., Sticher, O., Heinrich, M., Medical ethnobotany of the Zapotecs of the Isthmus-Sierra (Oaxaca, Mexico): Documentation and assessment of indigenous uses. J. Ethnopharmacol. 62 (1998), 149–165, 10.1016/S0378-8741(98)00051-8.
Funayama, S., Cordell, G., Alkaloids derived from tryptophan. Alkaloids: A Treasury of Poisons and Medicines, 2015, Academic Press, 63–102, 10.1016/B978-0-12-417302-6.00002-7.
Gairola, S., Sharma, J., Bedi, Y.S., A cross-cultural analysis of Jammu, Kashmir and Ladakh (India) medicinal plant use. J. Ethnopharmacol. 155 (2014), 925–986, 10.1016/j.jep.2014.06.029.
Gakuya, D.W., Itonga, S.M., Mbaria, J.M., Muthee, J.K., Musau, J.K., Ethnobotanical survey of biopesticides and other medicinal plants traditionally used in Meru central district of Kenya. J. Ethnopharmacol. 145 (2013), 547–553, 10.1016/j.jep.2012.11.028.
Garcez, W.S., Garcez, F.R., Honda, N.K., da Silva, A.J.R., A nitropropanoyl-glucopyranoside from Indigofera suffruticosa. Phytochemistry 28 (1989), 1251–1252, 10.1016/0031-9422(89)80220-1.
Garcez, W.S., Garcez, F.R., Barison, A., Additional 3-nitropropanoyl esters of glucose from Indigofera suffruticosa (Leguminosae). Biochem. Systemat. Ecol. 31 (2003), 207–209, 10.1016/S0305-1978(02)00087-X.
Ghorbani, A., Langenberger, G., Feng, L., Sauerborn, J., Ethnobotanical study of medicinal plants utilised by Hani ethnicity in Naban river Watershed National nature reserve, Yunnan, China. J. Ethnopharmacol. 134 (2011), 651–667, 10.1016/j.jep.2011.01.011.
Giday, Mirutse, Asfaw, Zemede, Woldu, Zerihun, Medicinal plants of the Meinit ethnic group of Ethiopia: an ethnobotanical study. J. Ethnopharmacol. 124 (2009), 513–521, 10.1016/j.jep.2009.05.009.
Gupta, M., Manikandan, L., Senthil, G.P., Anticancer activity of Indigofera aspalathoides and Wedelia calendulaceae in Swiss Albino mice. Iran. J. Pharm. Res. (IJPR) 6 (2007), 141–145.
Guruvaiah, P., Arunachalam, A., Velan, L.P.T., Evaluation of phytochemical constituents and antioxidant activities of successive solvent extracts of leaves of Indigofera caerulea Roxb using various in vitro antioxidant assay systems. Asian Pac. J. Trop. Dis. 2 (2012), S118–S123, 10.1016/S2222-1808(12)60136-4.
Gyamfi, M.A., Yonamine, M., Aniya, Y., Free-radical scavenging action of medicinal herbs from Ghana Thonningia sanguinea on experimentally-induced liver injuries. Gen. Pharmacol., 7, 1999.
Hamill, F.A., Apio, S., Mubiru, N.K., Mosango, M., Bukenya-Ziraba, R., Maganyi, O.W., Soejarto, D.D., Traditional herbal drugs of southern Uganda, I. J. Ethnopharmacol. 70 (2000), 281–300, 10.1016/S0378-8741(00)00180-X.
Hamill, F., Apio, S., Mubiru, N., Bukenya-Ziraba, R., Mosango, M., Maganyi, O., Soejarto, D., Traditional herbal drugs of Southern Uganda, II: literature analysis and antimicrobial assays. J. Ethnopharmacol. 84 (2003), 57–78, 10.1016/S0378-8741(02)00289-1.
Hamza, O.J.M., van den Bout-van den Beukel, C.J.P., Matee, M.I.N., Moshi, M.J., Mikx, F.H.M., Selemani, H.O., Mbwambo, Z.H., Van der Ven, A.J.A.M., Verweij, P.E., Antifungal activity of some Tanzanian plants used traditionally for the treatment of fungal infections. J. Ethnopharmacol. 108 (2006), 124–132, 10.1016/j.jep.2006.04.026.
Han, J., Traditional Chinese medicine and the search for new antineoplastic drugs. J. Ethnopharmacol. 24 (1988), 1–17, 10.1016/0378-8741(88)90135-3.
Hasan, A., Waterman, P., Iftikhar, N., The use of new chromatographic techniques for the isolation and purification of phenolic acids from Indigofera heterantha. J. Chromatogr. 466 (1989), 399–402.
Hasan, A., Farman, M., Iftikhar, A., Flavonoid glycosides from Indigofera hebepetala. Phytochemistry 35 (1994), 275–276.
Hasan, A., Ahmad, I., Khan, M.A., Chudhary, M.I., Two flavonol triglycosides from flowers of Indigofera hebepetala. Phytochemistry 43 (1996), 1115–1118, 10.1016/S0031-9422(96)00416-5.
Hassan, H., Sule, M., Musa, A., Musa, K., Abubakar, M., Hassan, A., Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants. Afr. J. Tradit., Complementary Altern. Med., 9, 2012, 10.4314/ajtcam.v9i2.10.
Hassan-Abdallah, A., Merito, A., Hassan, S., Aboubaker, D., Djama, M., Asfaw, Z., Kelbessa, E., Medicinal plants and their uses by the people in the Region of Randa, Djibouti. J. Ethnopharmacol. 148 (2013), 701–713, 10.1016/j.jep.2013.05.033.
Hemalatha, S., Subramanian, N., Ravichandran, V., Chinnaswamy, K., Wound-healing activity of Indigofera enneaphylla Linn. Indian J. Pharmaceut. Sci., 2001, 331–333.
Hilonga, S., Otieno, J.N., Ghorbani, A., Pereus, D., Kocyan, A., de Boer, H., Trade of wild-harvested medicinal plant species in local markets of Tanzania and its implications for conservation. South Afr. J. Bot., 2018, 10.1016/j.sajb.2018.08.012.
Hutchings, A., van Staden, J., Plants used for stress-related ailments in traditional Zulu, Xhosa and Sotho medicine. Part 1: plants used for headaches. J. Ethnopharmacol. 43 (1994), 89–124, 10.1016/0378-8741(94)90008-6.
Hutt, M., Houghton, P., A survey from the literature of plants used to treat scorpion stings. J. Ethnopharmacol. 60 (1998), 97–110, 10.1016/S0378-8741(97)00138-4.
Ijaz, F., Iqbal, Z., Rahman, I.U., Alam, J., Khan, S.M., Shah, G.M., Khan, K., Afzal, A., Investigation of traditional medicinal floral knowledge of Sarban Hills, Abbottabad, KP, Pakistan. J. Ethnopharmacol. 179 (2016), 208–233, 10.1016/j.jep.2015.12.050.
Inoue, S., Moriya, T., Morita, R., Kuwata, K., Thul, S.T., Sarangi, B.K., Minami, Y., Characterization of UDP-glucosyltransferase from Indigofera tinctoria. Plant Physiol. Biochem. 121 (2017), 226–233, 10.1016/j.plaphy.2017.11.002.
Jain, A., Katewa, S.S., Chaudhary, B.L., Galav, P., Folk herbal medicines used in birth control and sexual diseases by tribals of southern Rajasthan, India. J. Ethnopharmacol. 90 (2004), 171–177, 10.1016/j.jep.2003.09.041.
Josabad Alonso-Castro, A., Jose Maldonado-Miranda, J., Zarate-Martinez, A., Jacobo-Salcedo, M., del, R., Fernández-Galicia, C., Alejandro Figueroa-Zuñiga, L., Abel Rios-Reyes, N., Angel de León-Rubio, M., Andrés Medellín-Castillo, N., Reyes-Munguia, A., Méndez-Martínez, R., Carranza-Alvarez, C., Medicinal plants used in the Huasteca Potosina, México. J. Ethnopharmacol. 143 (2012), 292–298, 10.1016/j.jep.2012.06.035.
Junsongduang, A., Balslev, H., Inta, A., Jampeetong, A., Wangpakapattanawong, P., Karen and Lawa medicinal plant use: uniformity or ethnic divergence?. J. Ethnopharmacol. 151 (2014), 517–527, 10.1016/j.jep.2013.11.009.
Kamagaju, L., Bizuru, E., Minani, V., Morandini, R., Stévigny, C., Ghanem, G., Duez, P., An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation. J. Ethnopharmacol. 150 (2013), 708–717, 10.1016/j.jep.2013.09.031.
Kamal, R., Mangla, M., In vivo and in vitro investigations on rotenoids from Indigofera tinctoria and their bioefficacy against the larvae of Anopheles stephensi and adults of Callosobruchus chinensis. J. Biosci. 18 (1993), 93–101, 10.1007/BF02703041.
Kamatenesi-Mugisha, M., Oryem-Origa, H., Medicinal plants used to induce labour during childbirth in western Uganda. J. Ethnopharmacol. 109 (2007), 1–9, 10.1016/j.jep.2006.06.011.
Kankanamalage, T.N.M., Dharmadasa, R.M., Abeysinghe, D.C., Wijesekara, R.G.S., A survey on medicinal materials used in traditional systems of medicine in Sri Lanka. J. Ethnopharmacol. 155 (2014), 679–691, 10.1016/j.jep.2014.06.016.
Kankara, S.S., Ibrahim, M.H., Mustafa, M., Go, R., Ethnobotanical survey of medicinal plants used for traditional maternal healthcare in Katsina state, Nigeria. South Afr. J. Bot. 97 (2015), 165–175, 10.1016/j.sajb.2015.01.007.
Karakousi, C.-V., Gabrieli, C., Kokkalou, E., Chemical composition and biological activities of Indigofera hirsuta aerial parts' methanol fractions. Nat. Prod. Res., 2018, 1–5, 10.1080/14786419.2018.1489390.
Kaushik, N.K., Bagavan, A., Rahuman, A.A., Zahir, A.A., Kamaraj, C., Elango, G., Jayaseelan, C., Kirthi, A.V., Santhoshkumar, T., Marimuthu, S., Rajakumar, G., Tiwari, S.K., Sahal, D., Evaluation of antiplasmodial activity of medicinal plants from North Indian Buchpora and South Indian Eastern Ghats. Malar. J., 14, 2015, 65, 10.1186/s12936-015-0564-z.
Kaushik, N.K., Guha, R., Thomas, B.M., Antiviral potential and mode of action of Indigofera heterantha against HSV-2 by targeting the early stages of infection. Antivir. Ther. 22 (2016), 381–391, 10.3851/IMP3118.
Kayani, S., Ahmad, M., Sultana, S., Khan Shinwari, Z., Zafar, M., Yaseen, G., Hussain, M., Bibi, T., Ethnobotany of medicinal plants among the communities of Alpine and Sub-alpine regions of Pakistan. J. Ethnopharmacol. 164 (2015), 186–202, 10.1016/j.jep.2015.02.004.
Khatoon, S.S., Rehman, M., Rahman, A., The role of natural products in Alzheimer's and Parkinson's disease. Studies in Natural Products Chemistry, 2018, Elsevier, 69–127, 10.1016/B978-0-444-64058-1.00003-0.
Kidane, B., van Andel, T., van der Maesen, L., Asfaw, Z., Use and management of traditional medicinal plants by Maale and Ari ethnic communities in southern Ethiopia. J. Ethnobiol. Ethnomed., 10, 2014, 46, 10.1186/1746-4269-10-46.
Kittakoop, P., Anticancer drugs and potential anticancer leads inspired by natural products. Studies in Natural Products Chemistry, 2015, Elsevier, 251–307, 10.1016/B978-0-444-63460-3.00005-5.
Krishnamoorthy, J.R., Ranjith, M.S., Gokulshankar, S., Mohanty, B.K., Sumithra, R., Ranganathan, S., Babu, K., An overview of management of URTI and a novel approach towards RSV infection. Ghanei, M., (eds.) Respiratory Diseases, 2012, InTech, 10.5772/31134.
Kshirsagar, R.D., Singh, N.P., Some less known ethnomedicinal uses from Mysore and Coorg districts, Karnataka state, India. J. Ethnopharmacol. 75 (2001), 231–238, 10.1016/S0378-8741(01)00199-4.
Kulakkattolickal, A.T., Piscicidal plants of Nepal: preliminary toxicity screening using grass carp (Ctenopharyngodon idella) fingerlings. J. Ethnopharmacol., 1987, 1–9.
Kumar, B., Vijayakumar, M., Govindarajan, R., Pushpangadan, P., Ethnopharmacological approaches to wound-healing—exploring medicinal plants of India. J. Ethnopharmacol. 114 (2007), 103–113, 10.1016/j.jep.2007.08.010.
Kumar, R.S., Rajkapoor, B., Perumal, P., Antitumour and cytotoxic activities of methanol extract of Indigofera linnaei Ali. Asian Pac. J. Cancer Prev. APJCP 12 (2011), 613–618.
Kumar, R.S., Rajkapoor, B., Perumal, P., In vitro and in vivo anticancer activity of Indigofera cassioides Rottl. Ex. DC. Asian Pac. J. Trop. Med. 4 (2011), 379–385, 10.1016/S1995-7645(11)60108-9.
Kumar, D., Kumar, A., Prakash, O., Potential antifertility agents from plants: a comprehensive review. J. Ethnopharmacol. 140 (2012), 1–32, 10.1016/j.jep.2011.12.039.
Kumar, R.S., Rajkapoor, B., Perumal, P., Antioxidant activities of Indigofera cassioides Rottl. Ex. DC. using various in vitro assay models. Asian Pac. J. Trop. Biomed. 2 (2012), 256–261, 10.1016/S2221-1691(12)60019-7.
Kumar, S.S., Rao, M.R.K., Balasubramanian, M.P., Antiproliferative role of Indigofera aspalathoides on 20 methylcholanthrene induced fibrosarcoma in rats. Asian Pac. J. Trop. Biomed. 2 (2012), 966–974, 10.1016/S2221-1691(13)60008-8.
Kumar, R., Moorthy, K., Vinodhini, R., Punitha, T., Antimicrobial efficacy and phytochemical analysis of Indigofera trita Linn. Afr. J. Tradit., Complementary Altern. Med., 10, 2013, 10.4314/ajtcam.v10i3.20.
Kumar, R.S., Rajkapoor, B., Perumal, P., Anti-inflammatory and anti-nociceptive activities of methanolic leaf extract of Indigofera cassioides Rottl. Ex. DC. J. Acute Dis. 2 (2013), 322–326, 10.1016/S2221-6189(13)60152-3.
Kumar, K., Sharma, Y.P., Manhas, R.K., Bhatia, H., Ethnomedicinal plants of Shankaracharya Hill, Srinagar, J&K, India. J. Ethnopharmacol. 170 (2015), 255–274, 10.1016/j.jep.2015.05.021.
Labib, S., Berdai, M.-A., Bendadi, A., Achour, S., Harandou, M., Intoxication mortelle à l'Indigofera. Arch. Pediatr. 19 (2012), 59–61, 10.1016/j.arcped.2011.10.011.
Larsen, B.H.V., Soelberg, J., Jäger, A.K., COX-1 inhibitory effect of medicinal plants of Ghana. South Afr. J. Bot. 99 (2015), 129–131, 10.1016/j.sajb.2015.04.004.
Lasure, A., Van Poel, B., De Clerck, L.S., Bridts, C.H., Stevens, W.J., Rwangabo, P.C., Peters, L., Vlietinck, A.J., Screening of Rwandese plant extracts for their influence on lymphocyte proliferation. Phytomedicine 1 (1995), 303–307, 10.1016/S0944-7113(11)80007-3.
Ledoux, A., Cao, M., Jansen, O., Mamede, L., Campos, P.-E., Payet, B., Clerc, P., Grondin, I., Girard-Valenciennes, E., Hermann, T., Litaudon, M., Vanderheydt, C., Delang, L., Neyts, J., Leyssen, P., Frédérich, M., Smadja, J., Antiplasmodial, anti-chikungunya virus and antioxidant activities of 64 endemic plants from the Mascarene Islands. Int. J. Antimicrob. Agents 52 (2018), 622–628, 10.1016/j.ijantimicag.2018.07.017.
Leite, S.P., de Medeiros, P.L., da Silva, E.C., de Souza Maia, M.B., de Menezes Lima, V.L., Saul, D.E., Embryotoxicity in vitro with extract of Indigofera suffruticosa leaves. Reprod. Toxicol. 18 (2004), 701–705, 10.1016/j.reprotox.2004.04.004.
Leite, S.P., Vieira, J.R.C., de Medeiros, P.L., Leite, R.M.P., de Menezes Lima, V.L., Xavier, H.S., de Oliveira Lima, E., Antimicrobial activity of Indigofera suffruticosa. Evid. base Compl. Alternative Med. 3 (2006), 261–265, 10.1093/ecam/nel010.
Lev, E., Amar, Z., “Fossils” of practical medical knowledge from medieval Cairo. J. Ethnopharmacol. 119 (2008), 24–40, 10.1016/j.jep.2008.05.042.
Lima, I.R., Silva, I.B., Leite, R.M.P., Maia, M.B., Leite, S.P., Indican from Anil (Indigofera suffruticosa Miller) as an herbal protective agent to the liver. Anal. Quant. Cytopathol. Histopathol. 36 (2014), 41–45.
Lin, Y.-K., Chen, H.-W., Yang, S.-H., Leu, Y.-L., Huang, Y.-H., Yen, H.-C., Protective effect of indigo naturalis extract against oxidative stress in cultured human keratinocytes. J. Ethnopharmacol. 139 (2012), 893–896, 10.1016/j.jep.2011.12.037.
Liu, C.-X., He, W.-G., Leukogenic effect of complex indigo powder. J. Ethnopharmacol. 34 (1991), 83–86.
Lopes, F.C.M., Calvo, T.R., Colombo, L.L., Vilegas, W., Carlos, I.Z., Immunostimulatory and cytotoxic activities of Indigofera suffruticosa (Fabaceae). Nat. Prod. Res. 25 (2011), 1796–1806, 10.1080/14786419.2010.488624.
Lubbad, M.Y., Al-Quraishy, S., Dkhil, M.A., Antimalarial and antioxidant activities of Indigofera oblongifolia on Plasmodium chabaudi-induced spleen tissue injury in mice. Parasitol. Res. 114 (2015), 3431–3438, 10.1007/s00436-015-4568-y.
Luiz-Ferreira, A., Cola, M., Barbastefano, V., Farias-Silva, E., Calvo, T.R., de Almeida, A.B.A., Pellizzon, C.H., Hiruma-Lima, C.A., Vilegas, W., Souza-Brito, A.R.M., Indigofera suffruticosa Mill as new source of healing agent: involvement of prostaglandin and mucus and heat shock proteins. J. Ethnopharmacol. 137 (2011), 192–198, 10.1016/j.jep.2011.05.006.
Luiz-Ferreira, A., Cola, M., Barbastefano, V., de-Faria, F., Almeida, A., Farias-Silva, E., Calvo, T., Hiruma-Lima, C., Vilegas, W., Souza-Brito, A., Healing, antioxidant and cytoprotective properties of Indigofera truxillensis in different models of gastric ulcer in rats. Int. J. Mol. Sci. 13 (2012), 14973–14991, 10.3390/ijms131114973.
Machaba, T.C., Mahlo, S.M., McGaw, L.J., Biological activity of medicinal plants used in Venda for the treatment of fungal infections. South Afr. J. Bot., 115, 2018, 294, 10.1016/j.sajb.2018.02.067.
Madakkannu, B., Ravichandran, R., In vivo immunoprotective role of Indigofera tinctoria and Scoparia dulcis aqueous extracts against chronic noise stress induced immune abnormalities in Wistar albino rats. Toxicol. Rep. 4 (2017), 484–493, 10.1016/j.toxrep.2017.09.001.
Madhan Mohan, E., Krishna Mohan, C., Amudha, P., Effect of Indigofera tinctoria extracts on neurotransmitters concentrations in rat brain after induction of seizure. Int. J. Phytopharm. 1 (2010), 23–27.
Madikizela, B., Ndhlala, A.R., Finnie, J.F., Staden, J.V., In vitro antimicrobial activity of extracts from plants used traditionally in South Africa to treat tuberculosis and related symptoms. Evid. base Compl. Alternative Med. 2013 (2013), 1–8, 10.1155/2013/840719.
Madikizela, B., Ndhlala, A.R., Finnie, J.F., Van Staden, J., Antimycobacterial, anti-inflammatory and genotoxicity evaluation of plants used for the treatment of tuberculosis and related symptoms in South Africa. J. Ethnopharmacol. 153 (2014), 386–391, 10.1016/j.jep.2014.02.034.
Mahajan, P., Gnana Oli, R., Jachak, S.M., Bharate, S.B., Chaudhuri, B., Antioxidant and antiproliferative activity of indigocarpan, a pterocarpan from Indigofera aspalathoides. J. Pharm. Pharmacol. 68 (2016), 1331–1339, 10.1111/jphp.12609.
Mahmood, Adeel, Mahmood, Aqeel, Malik, R.N., Shinwari, Z.K., Indigenous knowledge of medicinal plants from Gujranwala district, Pakistan. J. Ethnopharmacol. 148 (2013), 714–723, 10.1016/j.jep.2013.05.035.
Majak, W., Benn, M., McEwan, D., Pass, M., Three nitropropanoyl esters of glucose from Indigofera linnaei. Phytochemistry 31 (1992), 2393–2395.
Malla, B., Gauchan, D.P., Chhetri, R.B., An ethnobotanical study of medicinal plants used by ethnic people in Parbat district of western Nepal. J. Ethnopharmacol. 165 (2015), 103–117, 10.1016/j.jep.2014.12.057.
Manandhar, N.P., Native phytotherapy among the Raute tribes of Dadeldhura district, Nepal. J. Ethnopharmacol. 60 (1998), 199–206, 10.1016/S0378-8741(97)00150-5.
Maregesi, S.M., Ngassapa, O.D., Pieters, L., Vlietinck, A.J., Ethnopharmacological survey of the Bunda district, Tanzania: plants used to treat infectious diseases. J. Ethnopharmacol. 113 (2007), 457–470, 10.1016/j.jep.2007.07.006.
Maregesi, S.M., Pieters, L., Ngassapa, O.D., Apers, S., Vingerhoets, R., Cos, P., Berghe, D.A.V., Vlietinck, A.J., Screening of some Tanzanian medicinal plants from Bunda district for antibacterial, antifungal and antiviral activities. J. Ethnopharmacol. 119 (2008), 58–66, 10.1016/j.jep.2008.05.033.
Marles, R.J., Farnsworth, N.R., Antidiabetic plants and their active constituents. Phytomedicine 2 (1995), 137–189, 10.1016/S0944-7113(11)80059-0.
Marquiafável, F.S., Ferreira, M.D.S., de Pádua Teixeira, S., Novel reports of glands in neotropical species of Indigofera L. (Leguminosae, Papilionoideae). Flora - Morphology, distribution. Funct. Ecol. Plant 204 (2009), 189–197, 10.1016/j.flora.2008.01.012.
Masondo, N.A., Stafford, G.I., Aremu, A.O., Makunga, N.P., Acetylcholinesterase inhibitors from southern African plants: an overview of ethnobotanical, pharmacological potential and phytochemical research including and beyond Alzheimer's disease treatment. South Afr. J. Bot., 2018, 10.1016/j.sajb.2018.09.011.
Mathabe, M.C., Nikolova, R.V., Lall, N., Nyazema, N.Z., Antibacterial activities of medicinal plants used for the treatment of diarrhoea in Limpopo Province, South Africa. J. Ethnopharmacol. 105 (2006), 286–293, 10.1016/j.jep.2006.01.029.
McGaw, L.J., Lall, N., Meyer, J.J.M., Eloff, J.N., The potential of South African plants against Mycobacterium infections. J. Ethnopharmacol. 119 (2008), 482–500, 10.1016/j.jep.2008.08.022.
Meenakshisundaram, A., Harikrishnan, T.J., Anna, T., Anthelmintic activity of Indigofera tinctoria against gastrointestinal nematodes of sheep. Vet. World 9 (2016), 101–106, 10.14202/vetworld.2016.101-106.
Meijer, L., Shearer, J., Bettayeb, K., Ferandin, Y., Diversity of the intracellular mechanisms underlying the anti-tumour properties of indirubins. Int. Congr. 1304 (2007), 60–74, 10.1016/j.ics.2007.07.041.
Mesfin, A., Giday, M., Animut, A., Teklehaymanot, T., Ethnobotanical study of antimalarial plants in Shinile District, Somali Region, Ethiopia, and in vivo evaluation of selected ones against Plasmodium berghei. J. Ethnopharmacol. 139 (2012), 221–227, 10.1016/j.jep.2011.11.006.
Mohagheghzadeh, A., Faridi, P., Shams-Ardakani, M., Ghasemi, Y., Medicinal smokes. J. Ethnopharmacol. 108 (2006), 161–184, 10.1016/j.jep.2006.09.005.
Molander, M., Nielsen, L., Søgaard, S., Staerk, D., Rønsted, N., Diallo, D., Chifundera, K.Z., van Staden, J., Jäger, A.K., Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa. J. Ethnopharmacol. 157 (2014), 171–180, 10.1016/j.jep.2014.09.027.
Moneim, A., Dkhil, M., Al-Khalifa, M., Al-Quraishy, S., Zrieq, R., Indigofera oblongifolia mitigates lead-acetate-induced kidney damage and apoptosis in a rat model. Drug Des. Dev. Ther., 1847, 2016, 10.2147/DDDT.S105511.
Moreno-Salazar, S.F., Robles-Zepeda, R.E., Johnson, D.E., Plant folk medicines for gastrointestinal disorders among the main tribes of Sonora, Mexico. Fitoterapia 79 (2008), 132–141, 10.1016/j.fitote.2007.07.009.
Moteetee, A., Moffett, R.O., Seleteng-Kose, L., A review of the ethnobotany of the Basotho of Lesotho and the free State Province of South Africa (South Sotho). South Afr. J. Bot., 2018, 10.1016/j.sajb.2017.12.012.
Mugisha, M.K., Asiimwe, S., Namutebi, A., Borg-Karlson, A.-K., Kakudidi, E.K., Ethnobotanical study of indigenous knowledge on medicinal and nutritious plants used to manage opportunistic infections associated with HIV/AIDS in western Uganda. J. Ethnopharmacol. 155 (2014), 194–202, 10.1016/j.jep.2014.05.012.
Mukazayire, M.-J., Minani, V., Ruffo, C.K., Bizuru, E., Stévigny, C., Duez, P., Traditional phytotherapy remedies used in Southern Rwanda for the treatment of liver diseases. J. Ethnopharmacol. 138 (2011), 415–431, 10.1016/j.jep.2011.09.025.
Muthee, J.K., Gakuya, D.W., Mbaria, J.M., Kareru, P.G., Mulei, C.M., Njonge, F.K., Ethnobotanical study of anthelmintic and other medicinal plants traditionally used in Loitoktok district of Kenya. J. Ethnopharmacol. 135 (2011), 15–21, 10.1016/j.jep.2011.02.005.
Mutheeswaran, S., Pandikumar, P., Chellappandian, M., Ignacimuthu, S., Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India. J. Ethnopharmacol. 137 (2011), 523–533, 10.1016/j.jep.2011.06.003.
Mutheeswaran, S., Kumar, P.S., Yuvaraj, P., Duraipandiyan, V., Abdullah Al-Dhabi, N., Balakrishna, K., Ignacimuthu, S., Screening of some medicinal plants for anticariogenic activity: an investigation on bioactive constituents from Jatropha gossypifolia (L.) root. Biocatal. Agric. Biotechnol. 10 (2017), 161–166, 10.1016/j.bcab.2017.03.006.
Nadembega, P., Boussim, J.I., Nikiema, J.B., Poli, F., Antognoni, F., Medicinal plants in Baskoure, Kourittenga Province, Burkina Faso: an ethnobotanical study. J. Ethnopharmacol. 133 (2011), 378–395, 10.1016/j.jep.2010.10.010.
Namukobe, J., Kasenene, J.M., Kiremire, B.T., Byamukama, R., Kamatenesi-Mugisha, M., Krief, S., Dumontet, V., Kabasa, J.D., Traditional plants used for medicinal purposes by local communities around the Northern sector of Kibale National Park, Uganda. J. Ethnopharmacol. 136 (2011), 236–245, 10.1016/j.jep.2011.04.044.
Narender, T., Khaliq, T., Puri, A., chander, R., Antidyslipidemic activity of furano-flavonoids isolated from Indigofera tinctoria. Bioorg. Med. Chem. Lett 16 (2006), 3411–3414, 10.1016/j.bmcl.2006.04.001.
Neuwinger, H.D., Plants used for poison fishing in tropical Africa. Toxicon 44 (2004), 417–430, 10.1016/j.toxicon.2004.05.014.
Ngezahayo, J., Havyarimana, F., Hari, L., Stévigny, C., Duez, P., Medicinal plants used by Burundian traditional healers for the treatment of microbial diseases. J. Ethnopharmacol. 173 (2015), 338–351, 10.1016/j.jep.2015.07.028.
Okatch, H., Ngwenya, B., Raletamo, K.M., Andrae-Marobela, K., Determination of potentially toxic heavy metals in traditionally used medicinal plants for HIV/AIDS opportunistic infections in Ngamiland District in Northern Botswana. Anal. Chim. Acta 730 (2012), 42–48, 10.1016/j.aca.2011.11.067.
Omprakash, K., Subash Chandran, G., Velpandian, V., Indigofera aspalathoides Vahl ex. DC (Sivanar Vembu): a phytopharmacological review. Int. J. Pharmaceut. Sci. Res. 4 (2013), 3775–3781.
Paksoy, M.Y., Diraz, E., Diğrak, M., Tutar, E., Karaman, Ş., Essential oil composition and antimicrobial activity of two endemic Kundmannia SCOP. species from Turkey. Ind. Crop. Prod. 79 (2016), 39–46, 10.1016/j.indcrop.2015.10.027.
Palani, S., Kumar, R., Kumar, B., Effect of the ethanolic extract of Indigofera barberi (L.) in acute acetaminophen induced nephrotoxic rats. N. Biotech., 25S, 2009, 14.
Pan, L., Chai, H., Kinghorn, A.D., The continuing search for antitumour agents from higher plants. Phytochem. Lett. 3 (2010), 1–8, 10.1016/j.phytol.2009.11.005.
Panda, S.K., Ethno-medicinal uses and screening of plants for antibacterial activity from Similipal Biosphere Reserve, Odisha, India. J. Ethnopharmacol. 151 (2014), 158–175, 10.1016/j.jep.2013.10.004.
Paramashivam, S.K., Natarajan, B., Ramamoorthy, M., Balasubramanian, S., Elayaperumal, K., Dhiraviam, K.N., In silico pharmacokinetic and molecular docking studies of small molecules derived from Indigofera aspalathoides Vahl targeting receptor tyrosine kinases. Bioinformation 11 (2015), 73–84, 10.6026/97320630011073.
Philips, A., Philip, S., Arul, V., Padmakeerthiga, B., Renju, V., Santha, S., Sethupathy, S., Free radical scavenging activity of leaf extracts of Indigofera aspalathoides – an in vitro analysis. J. Pharmaceut. Sci. Res. 2 (2010), 322–328.
Pistelli, L., Secondary metabolites of genus Astragalus: structure and biological activity. Studies in Natural Products Chemistry, 2002, Elsevier, 443–545, 10.1016/S1572-5995(02)80043-6.
Ponmari, G., Annamalai, A., Gopalakrishnan, V.K., Lakshmi, P.T.V., Guruvayoorappan, C., NF-κB activation and proinflammatory cytokines mediated protective effect of Indigofera caerulea Roxb. on CCl4 induced liver damage in rats. Int. Immunopharm. 23 (2014), 672–680, 10.1016/j.intimp.2014.10.021.
Poullain, C., Girard-Valenciennes, E., Smadja, J., Plants from reunion island: evaluation of their free radical scavenging and antioxidant activities. J. Ethnopharmacol. 95 (2004), 19–26, 10.1016/j.jep.2004.05.023.
Prabhu, S., Vijayakumar, S., Yabesh, J.E.M., Ravichandran, K., Sakthivel, B., Documentation and quantitative analysis of the local knowledge on medicinal plants in Kalrayan hills of Villupuram district, Tamil Nadu, India. J. Ethnopharmacol. 157 (2014), 7–20, 10.1016/j.jep.2014.09.014.
Priya, S., Kumar, N.S., Hemalatha, S., Antiviral phytocompounds target envelop protein to control Zika virus. Comput. Biol. Chem. 77 (2018), 402–412, 10.1016/j.compbiolchem.2018.08.008.
Puri, A., Khaliq, T., Rajendran, S.M., Bhatia, G., Chandra, R., Narender, T., Antidyslipidemic activity of Indigofera tinctoria. J. Herb. Pharmacother. 7 (2007), 57–64, 10.1300/J157v07n01_05.
Qiu, L., Liang, Y., Tang, G.-H., Yuan, C.-M., Zhang, Y., Hao, X.-Y., Hao, X.-J., He, H.-P., Two new flavonols, including one flavan dimer, from the roots of Indigofera stachyodes. Phytochem. Lett. 6 (2013), 368–371, 10.1016/j.phytol.2013.04.010.
Rahman, T.U., Uddin, G., Nisa, R.U., Ludwig, R., Liaqat, W., Mahmood, T., Mohammad, G., Choudhary, M.I., Ayub, K., Spectroscopic and density functional theory studies of 7-hydroxy-3′-methoxyisoflavone: a new isoflavone from the seeds of Indigofera heterantha (Wall). Spectrochim. Acta Mol. Biomol. Spectrosc. 148 (2015), 375–381, 10.1016/j.saa.2015.04.018.
Rahman, I.U., Ijaz, F., Afzal, A., Iqbal, Z., Ali, N., Khan, S.M., Contributions to the phytotherapies of digestive disorders: traditional knowledge and cultural drivers of Manoor Valley, Northern Pakistan. J. Ethnopharmacol. 192 (2016), 30–52, 10.1016/j.jep.2016.06.049.
Rahman, I.U., Ijaz, F., Iqbal, Z., Afzal, A., Ali, N., Afzal, M., Khan, M.A., Muhammad, S., Qadir, G., Asif, M., A novel survey of the ethno medicinal knowledge of dental problems in Manoor Valley (Northern Himalaya), Pakistan. J. Ethnopharmacol. 194 (2016), 877–894, 10.1016/j.jep.2016.10.068.
Rahman, T.U., Zeb, M.A., Liaqat, W., Sajid, M., Hussain, S., Choudhary, M.I., Phytochemistry and pharmacology of genus Indigofera: a review. Record Nat. Prod. 12 (2017), 1–13, 10.25135/rnp.13.16.12.585.
Rajaperumal, S., Nimmi, M., Kumari, B.D.R., In vitro studies on antimicrobial and antioxidant effect of methanolic extract of Indigofera aspalathoides (Vahl ex DC) and its cytotoxic property against human lung cancer cell line NCI H460. Eur. J. Exp. Biol. 3 (2013), 18–29.
Rajendra Kopalli, S., Koppula, S., Young Shin, K., Noh, S.-J., Jin, Q., Yeon Hwang, B., Suh, Y.-H., SF-6 attenuates 6-hydroxydopamine-induced neurotoxicity: an in vitro and in vivo investigation in experimental models of Parkinson's disease. J. Ethnopharmacol. 143 (2012), 686–694, 10.1016/j.jep.2012.07.032.
Rajkapoor, B., Jayakar, B., Murugesh, N., Antitumour activity of Indigofera aspalathoides on Erlich ascites carcinoma in mice. Indian J. Pharmacol. 36 (2004), 38–40.
Rajkapoor, B., Murugesh, N., Chodon, D., Sakthisekaran, D., Chemoprevention of N-nitrosodiethylamine induced phenobarbitol promoted liver tumours in rat by extract of Indigofera aspalathoides. Biol. Pharm. Bull. 28 (2005), 364–366, 10.1248/bpb.28.364.
Rajkapoor, B., Kavimani, S., Ravichandiran, V., Sekhar, K., Kumar, R.S., Kumar, M.R., Pradeepkumar, M., Einstein, J.W., Kumar, E.P., Effect of Indigofera aspalathoides on complete Freund's adjuvant-induced arthritis in rats. Pharmaceut. Biol. 47 (2009), 553–557, 10.1080/13880200902902489.
Ramos, A., Visozo, A., Piloto, J., Garcı́a, A., Rodrı́guez, C.A., Rivero, R., Screening of antimutagenicity via antioxidant activity in Cuban medicinal plants. J. Ethnopharmacol. 87 (2003), 241–246, 10.1016/S0378-8741(03)00156-9.
Ranjarisoa, L.N., Razanamihaja, N., Rafatro, H., Use of plants in oral health care by the population of Mahajanga, Madagascar. J. Ethnopharmacol. 193 (2016), 179–194, 10.1016/j.jep.2016.07.076.
Rehman, A., Malik, A., Mehmood, S., Jahan, E., Ahmad, H., Phytochemical studies on Indigofera hetrantha. J. Chem. Soc. Pakistan 27 (2005), 440–442.
Remigio, A.C., Piloto, J., Vega, Y., Rodriguez, C., Carballo, C., Garcia, A., Guerra, M., Sanchez, E., Positive genotoxic activity of plants used in Cuba. Toxicol. Lett., 180, 2008, 241.
Renukadevi, K.P., Suhani Sultana, S., Determination of antibacterial, antioxidant and cytotoxicity effect of Indigofera tinctoria on lung cancer cell line NCI-h69. Int. J. Pharmacol. 7 (2011), 356–362.
Risa, J., Risa, A., Adsersen, A., Gauguin, B., Stafford, G.I., van Staden, J., Jäger, A.K., Screening of plants used in southern Africa for epilepsy and convulsions in the GABAA-benzodiazepine receptor assay. J. Ethnopharmacol. 93 (2004), 177–182, 10.1016/j.jep.2004.01.021.
Rodrigues de Almeida, E., Leal de Almeida Luna, R., Roberto da Silva, A., Cavalcanti Aragão-Neto, A., Luiz Soares da Silva, L., Bosco Lindoso Couto, G., Anticonvulsant effect of Indigofera suffruticosa Mill: Indication of involvement of the GABAergic system. Afr. J. Pharm. Pharmacol. 7 (2013), 622–628, 10.5897/AJPP12.1262.
Rüegg, T., Calderón, A.I., Queiroz, E.F., Solís, P.N., Marston, A., Rivas, F., Ortega-Barría, E., Hostettmann, K., Gupta, M.P., 3-Farnesyl-2-hydroxybenzoic acid is a new anti-helicobacter pylori compound from Piper multiplinervium. J. Ethnopharmacol. 103 (2006), 461–467, 10.1016/j.jep.2005.09.014.
Rupani, R., Chavez, A., Medicinal plants with traditional use: ethnobotany in the Indian subcontinent. Clin. Dermatol. 36 (2018), 306–309, 10.1016/j.clindermatol.2018.03.005.
Saganuwan, S.A., Tropical plants with fertility and infertility value. Maturitas 81 (2015), 195–196, 10.1016/j.maturitas.2015.02.280.
Salam Abdullah, A., Rajion, M.A., Dietary factors affecting entero-hepatic function of ruminants in the tropics. Anim. Feed Sci. Technol. 69 (1997), 79–90, 10.1016/S0377-8401(97)81624-0.
Salihu Shinkafi, T., Bello, L., Wara Hassan, S., Ali, S., An ethnobotanical survey of antidiabetic plants used by Hausa–Fulani tribes in Sokoto, Northwest Nigeria. J. Ethnopharmacol. 172 (2015), 91–99, 10.1016/j.jep.2015.06.014.
Samuelsson, G., Farah, M.H., Claeson, P., Hagos, M., Thulin, M., Hedberg, O., Warfa, A.M., Hassan, A.O., Elmi, A.H., Abdurahman, A.D., Elmi, A.S., Abdi, Y.A., Alin, M.H., Inventory of plants used in traditional medicine in Somalia. III. Plants of the families Lauraceae-Papilionaceae. J. Ethnopharmacol. 37 (1992), 93–112, 10.1016/0378-8741(92)90068-3.
Saravana Kumar, A., Gandhimathi, R., Mohana Lakshmi, S., Rahul, N., Ashok Kumar, C.K., Evaluation of the antinociceptive properties from Indigofera tinctoria leaves extracts. J. Pharmaceut. Sci. Res. 1 (2009), 31–37.
Saritha, B., Brindha, P., Evaluation of wound-healing activity of Indigofera aspalathoides Vahl. ex DC. - a traditional Siddha drug. Int. J. Pharm. Pharmaceut. Sci. 4 (2012), 40–44.
Sathasivampillai, S.V., Rajamanoharan, P.R.S., Munday, M., Heinrich, M., Plants used to treat diabetes in Sri Lankan Siddha Medicine – an ethnopharmacological review of historical and modern sources. J. Ethnopharmacol. 198 (2017), 531–599, 10.1016/j.jep.2016.07.053.
Savithramma, N., Sulochana, C., Rao, K.N., Ethnobotanical survey of plants used to treat asthma in Andhra Pradesh, India. J. Ethnopharmacol. 113 (2007), 54–61, 10.1016/j.jep.2007.04.004.
Schrire, B., A review of tribe Indigofereae (Leguminosae–Papilionoideae) in Southern Africa (including South Africa, Lesotho, Swaziland & Namibia; excluding Botswana). South Afr. J. Bot. 89 (2013), 281–283, 10.1016/j.sajb.2013.06.014.
Schrire, B.D., Lavin, M., Barker, N.P., Forest, F., Phylogeny of the tribe Indigofereae (Leguminosae-Papilionoideae): geographically structured more in succulent-rich and temperate settings than in grass-rich environments. Am. J. Bot. 96 (2009), 816–852, 10.3732/ajb.0800185.
Selvam, C., Jachak, S.M., Gnana Oli, R., Thilagavathi, R., Chakraborti, A.K., Bhutani, K.K., A new cyclooxygenase (COX) inhibitory pterocarpan from Indigofera aspalathoides: structure elucidation and determination of binding orientations in the active sites of the enzyme by molecular docking. Tetrahedron Lett. 45 (2004), 4311–4314, 10.1016/j.tetlet.2004.04.010.
Sen, A., Banerjee, N., A water-soluble galactomannan from the seeds of Indigofera tinctoria Linn. Carbohydr. Res. 157 (1986), 251–256.
Shah, U., Shah, R., Acharya, S., Acharya, N., Novel anticancer agents from plant sources. Chin. J. Nat. Med. 11 (2013), 16–23, 10.1016/S1875-5364(13)60002-3.
Shah, A., Bharati, K.A., Ahmad, J., Sharma, M.P., New ethnomedicinal claims from Gujjar and Bakerwals tribes of Rajouri and Poonch districts of Jammu and Kashmir, India. J. Ethnopharmacol. 166 (2015), 119–128, 10.1016/j.jep.2015.01.056.
Shah, S.A., Shah, N.A., Ullah, Shafi, Alam, M.M., Badshah, H., Ullah, Sana, Mumtaz, A.S., Documenting the indigenous knowledge on medicinal flora from communities residing near Swat River (Suvastu) and in high mountainous areas in Swat-Pakistan. J. Ethnopharmacol. 182 (2016), 67–79, 10.1016/j.jep.2016.02.008.
Sharif, A., Ahmed, E., Malik, A., Riaz, N., Afza, N., Nawaz, S.A., Arshad, M., Shah, M.R., Choudhary, M.I., Lipoxygenase inhibitory constituents fromIndigofera oblongifolia. Arch Pharm. Res. (Seoul) 28 (2005), 761–764, 10.1007/BF02977339.
Sharma, V., Agarwal, A., Physicochemical and antioxidant assays of methanol and hydromethanol extract of aerial parts of Indigofera tinctoria Linn. Indian J. Pharmaceut. Sci. 77 (2015), 729–734.
Sharma, J., Gairola, S., Gaur, R.D., Painuli, R.M., The treatment of jaundice with medicinal plants in indigenous communities of the Sub-Himalayan region of Uttarakhand, India. J. Ethnopharmacol. 143 (2012), 262–291, 10.1016/j.jep.2012.06.034.
Shcherbukhin, V.D., Galactomannans from seeds of the leguminous plants found in the Soviet Union. Food Hydrocolloids 6 (1992), 3–7, 10.1016/S0268-005X(09)80054-4.
Sher, H., Aldosari, A., Ali, A., de Boer, H.J., Indigenous knowledge of folk medicines among tribal minorities in Khyber Pakhtunkhwa, northwestern Pakistan. J. Ethnopharmacol. 166 (2015), 157–167, 10.1016/j.jep.2015.03.022.
Silambarasan, R., Ayyanar, M., An ethnobotanical study of medicinal plants in Palamalai region of Eastern Ghats, India. J. Ethnopharmacol. 172 (2015), 162–178, 10.1016/j.jep.2015.05.046.
Silva, A.R., Fagundes, C.M.S., Andrade-da-Costa, B.L.S., Rodrigues, M.C.A., Anticonvulsant properties of Indigofera suffruticosa in the intrahippocampal pilocarpine model in rats. Epilepsy Behav. 38 (2014), 212–213, 10.1016/j.yebeh.2014.08.104.
Singh, R., Sharma, S., Sharma, V., Comparative and quantitative analysis of antioxidant and scavenging potential of Indigofera tinctoria Linn. extracts. J. Integr. Med. 13 (2015), 269–278, 10.1016/S2095-4964(15)60183-2.
Sivagamy, M., Jeganathan, N., Manavalan, R., Senthamarai, R., Wound-healing activity of Indigofera enneaphylla Linn. Int. J. Adv. Pharm. 1 (2012), 211–214.
Sivasankari, B., Anandharaj, M., Gunasekaran, P., An ethnobotanical study of indigenous knowledge on medicinal plants used by the village peoples of Thoppampatti, Dindigul district, Tamilnadu, India. J. Ethnopharmacol. 153 (2014), 408–423, 10.1016/j.jep.2014.02.040.
Soelberg, J., Asase, A., Akwetey, G., Jäger, A.K., Historical versus contemporary medicinal plant uses in Ghana. J. Ethnopharmacol. 160 (2015), 109–132, 10.1016/j.jep.2014.11.036.
Srinivasan, S., Loganathan, S., Wankhar, W., Rathinasamy, S., Rajan, R., Stress effect on humoral and cell mediated immune response: Indispensable part of corticosterone and cytokine in neutrophil function. Trials Vaccinol. 5 (2016), 61–70, 10.1016/j.trivac.2016.04.002.
Srinivasan, S., Wankhar, W., Rathinasamy, S., Rajan, R., Free radical scavenging potential and HPTLC analysis of Indigofera tinctoria linn (Fabaceae). J. Pharmaceut. Anal. 6 (2016), 125–131, 10.1016/j.jpha.2015.04.003.
Ssegawa, P., Kasenene, J.M., Medicinal plant diversity and uses in the Sango bay area, Southern Uganda. J. Ethnopharmacol. 113 (2007), 521–540, 10.1016/j.jep.2007.07.014.
Stangeland, T., Alele, P.E., Katuura, E., Lye, K.A., Plants used to treat malaria in Nyakayojo sub-county, western Uganda. J. Ethnopharmacol. 137 (2011), 154–166, 10.1016/j.jep.2011.05.002.
Steenkamp, V., Traditional herbal remedies used by South African women for gynaecological complaints. J. Ethnopharmacol. 86 (2003), 97–108, 10.1016/S0378-8741(03)00053-9.
Su, Y., Lü, M., Yang, F., Li, C., Di, L., Wu, D., Guo, Z., Lü, J., Guo, D., Six new glucose esters of 3-nitropropanoic acid from Indigofera kirilowii. Fitoterapia 79 (2008), 451–455, 10.1016/j.fitote.2008.04.006.
Suleman, S., Beyene Tufa, T., Kebebe, D., Belew, S., Mekonnen, Y., Gashe, F., Mussa, S., Wynendaele, E., Duchateau, L., De Spiegeleer, B., Treatment of malaria and related symptoms using traditional herbal medicine in Ethiopia. J. Ethnopharmacol. 213 (2018), 262–279, 10.1016/j.jep.2017.10.034.
Sultan, S., Osborne, S.A., Addepalli, R., Netzel, G., Netzel, M.E., Fletcher, M.T., Indospicine cytotoxicity and transport in human cell lines. Food Chem. 267 (2018), 119–123, 10.1016/j.foodchem.2017.08.029.
Suma, T.S., Ravikumar, K., Somashekhar, B.S., Ved, D.K., Zaman, R., Rajalakshmi, G., Nair, S.N.V., Kukkupuni, S.K., Documentation of ‘plant drugs’ dispensed via local weekly shanties of Madurai city, India. J. Ayurveda Integr. Med. 9 (2018), 104–112, 10.1016/j.jaim.2017.05.008.
Sundarrajan, S., Arumugam, M., Documentation of traditional Siddha medicines for skin diseases from Katpadi taluk, Vellore district, Tamil Nadu, India. Eur. J. Integr. Med. 9 (2017), 52–62, 10.1016/j.eujim.2016.08.163.
Sundarrajan, S., Arumugam, M., A systems pharmacology perspective to decipher the mechanism of action of Parangichakkai chooranam, a Siddha formulation for the treatment of psoriasis. Biomed. Pharmacother. 88 (2017), 74–86, 10.1016/j.biopha.2016.12.135.
Tabuti, J.R., Lye, K., Dhillion, S., Traditional herbal drugs of Bulamogi, Uganda: plants, use and administration. J. Ethnopharmacol. 88 (2003), 19–44, 10.1016/S0378-8741(03)00161-2.
Tapsoba, H., Deschamps, J.-P., Use of medicinal plants for the treatment of oral diseases in Burkina Faso. J. Ethnopharmacol. 104 (2006), 68–78, 10.1016/j.jep.2005.08.047.
Techer, S., Criblage d'activités biologiques de plantes endémiques ou indigènes de La Réunion - Recherche de molécules antivirales ciblant le virus du chikungunya. 2013, Université de La Réunion.
Teklehaymanot, T., An ethnobotanical survey of medicinal and edible plants of Yalo Woreda in Afar regional state, Ethiopia. J. Ethnobiol. Ethnomed., 13, 2017, 10.1186/s13002-017-0166-7.
Teklehaymanot, T., Giday, M., Quantitative ethnobotany of medicinal plants used by Kara and Kwego semi-pastoralist people in lower Omo river valley, Debub Omo Zone, Southern Nations, nationalities and peoples regional State, Ethiopia. J. Ethnopharmacol. 130 (2010), 76–84, 10.1016/j.jep.2010.04.013.
Thangadurai, D., Ramesh, N., Viswanathan, M., Prasad, D.X., A novel xanthene from Indigofera longeracemosa stem. Fitoterapia 72 (2001), 92–94, 10.1016/S0367-326X(00)00236-7.
Thas, J.J., Siddha Medicine—background and principles and the application for skin diseases. Clin. Dermatol. 26 (2008), 62–78, 10.1016/j.clindermatol.2007.11.010.
Upadhyay, B., Parveen Dhaker, A.K., Kumar, A., Ethnomedicinal and ethnopharmaco-statistical studies of Eastern Rajasthan, India. J. Ethnopharmacol. 129 (2010), 64–86, 10.1016/j.jep.2010.02.026.
Vásquez, J., Alarcón, J.C., Jiménez, S.L., Jaramillo, G.I., Gómez-Betancur, I.C., Rey-Suárez, J.P., Jaramillo, K.M., Muñoz, D.C., Marín, D.M., Romero, J.O., Main plants used in traditional medicine for the treatment of snake bites n the regions of the department of Antioquia, Colombia. J. Ethnopharmacol. 170 (2015), 158–166, 10.1016/j.jep.2015.04.059.
Verma, S.M., Suresh, K.B., Verma, A., Antidiabetic activity of leaves of Indigofera tinctoria Linn (Fabaceae). Int. J. Toxicol. Pharmacol. Res. 1 (2009), 42–43.
Vieira, J.R.C., de Souza, I.A., do Nascimento, S.C., Leite, S.P., Indigofera suffruticosa: an alternative anticancer therapy. Evid. base Compl. Alternative Med. 4 (2007), 355–359, 10.1093/ecam/nel102.
Vieira, J.R.C., Leite, R.M.P., Lima, I.R., Navarro, D. do A.F., Bianco, E.M., Leite, S.P., Oviposition and embryotoxicity of Indigofera suffruticosa on early development of Aedes aegypti (Diptera: Culicidae). Evid. base Compl. Alternative Med. 2012 (2012), 1–5, 10.1155/2012/741638.
Vlietinck, A.J., Van Hoof, L., Totté, J., Lasure, A., Berghe, D.V., Rwangabo, P.C., Mvukiyumwami, J., Screening of hundred Rwandese medicinal plants for antimicrobial and antiviral properties. J. Ethnopharmacol. 46 (1995), 31–47, 10.1016/0378-8741(95)01226-4.
Wagh, V.V., Jain, A.K., Status of ethnobotanical invasive plants in western Madhya Pradesh, India. South Afr. J. Bot. 114 (2018), 171–180, 10.1016/j.sajb.2017.11.008.
Whistler, W.A., Herbal medicine in the Kingdom of Tonga. J. Ethnopharmacol. 31 (1991), 339–372, 10.1016/0378-8741(91)90020-E.
Yazbek, P.B., Tezoto, J., Cassas, F., Rodrigues, E., Plants used during maternity, menstrual cycle and other women's health conditions among Brazilian cultures. J. Ethnopharmacol. 179 (2016), 310–331, 10.1016/j.jep.2015.12.054.
Zhang, X.-X., Zhang, Z.-X., Chen, L., Su, Y.-F., New aliphatic nitro-compounds from Indigofera carlesii. Fitoterapia 77 (2006), 15–18, 10.1016/j.fitote.2005.06.015.
Zhang, Y.-F., Zhu, Z.-X., Sun, H., Yao, H.-N., Chen, X.-N., Liu, L., Zhang, S.-L., Zhao, Y.-F., Tu, P.-F., Li, J., Stachyodin A, a pterocarpan derivative with unusual spirotetrahydrofuran ring from the roots of Indigofera stachyodes. Tetrahedron Lett. 59 (2018), 4514–4516, 10.1016/j.tetlet.2018.11.024.
