Article (Scientific journals)
Strychnohexamine from Strychnos icaja, a naturally occurring trimeric indolomonoterpenic alkaloid
Philippe, Geneviève; Prost, E.; Nuzillard, J. M. et al.
2002In Tetrahedron Letters, 43 (18), p. 3387-3390
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Keywords :
strychnohexamine; Strychnos icaja; indolomonoterpenic alkaloid; trimer
Abstract :
[en] A reinvestigation of Strychnos icaja roots has resulted in the isolation, from the EtOAC extract, of one tertiary trisindole alkaloid, named strychnohexamine. Its structure has been investigated by means of spectroscopic data interpretation (UV. IR. HRESIMS. 1D and 2D NMR). This is the first time that a natural trimeric indolomonoterpenic alkaloid has been isolated directly from a plant species. This compound is one of the largest alkaloids ever discovered. (C) 2002 Elsevier Science Ltd. All rights reserved.
Disciplines :
Pharmacy, pharmacology & toxicology
Phytobiology (plant sciences, forestry, mycology...)
Chemistry
Author, co-author :
Philippe, Geneviève  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Prost, E.
Nuzillard, J. M.
Zeches-Hanrot, M.
Tits, Monique ;  Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Frederich, Michel  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
Strychnohexamine from Strychnos icaja, a naturally occurring trimeric indolomonoterpenic alkaloid
Publication date :
29 April 2002
Journal title :
Tetrahedron Letters
ISSN :
0040-4039
Publisher :
Pergamon-Elsevier Science Ltd, Oxford, United Kingdom
Volume :
43
Issue :
18
Pages :
3387-3390
Peer reviewed :
Peer Reviewed verified by ORBi
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