[en] Four Fumaria species (F. vaillantii Loisel, F. parviflora Lam., F. rostellata Knaf and F. jankae Hausskn.) were analysed in order to determine the presence of the isoquinoline alkaloids allocryptopine, chelidonine, protopine, bicuculline, sanguinarine, cheleritrine, stylopine, and hydrastine through an HPLC-DAD method. Protopine and sanguinarine were present in all extracts. Bicuculline and stylopine were found in F. vaillantii and F. parviflora, whilst chelidonine was identified only in F. vaillantii and hydrastine in F. jankae, so they represent potential taxonomic markers that differentiate the four plants. The richest species in isoquinoline alkaloids was F. parviflora. Our study showed significant differences between the four Fumaria species, both qualitative and quantitative.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Paltinean, Ramona
Toju, A
Wauters, Jean-Noël ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
Frederich, Michel ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Tits, Monique ; Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
Tamas, M
Crisan, G
Language :
English
Title :
Identification and determination of alkaloids in Fumaria Species from Romania
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