[en] Moandaensine contains a rare anhydronium base subunit. It presents a moderate antiplasmodial activity with IC values of 11.2 microM and 9.2 microM against , respectively, the chloroquino sensitive FCA 20 GHA and chloroquino resistant W2 strains of Plasmodium falciparum
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Verpoorte, Robert
Frederich, Michel ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Delaude, Clément ; Université de Liège - ULiège > Relations académiques et scientifiques (Sciences)
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Dive, Georges ; Université de Liège - ULiège > Centre d'ingénierie des protéines
Thépenier, Philippe
Jacquier, Marie-José
Zèches-Hanrot, Monique
Lavaud, Catherine
Nuzillard, Jean-Marc
Language :
English
Title :
Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae)
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