Perturbation of Codon-Specific mRNA  Translation Reshapes MHC-II Tumor Antigen Presentation

Seca, Christian

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Doctoral thesis (Dissertations and theses)

Perturbation of Codon-Specific mRNA Translation Reshapes MHC-II Tumor Antigen Presentation

Seca, Christian

2025

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https://hdl.handle.net/2268/334726

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Keywords :

Wobble uridine tRNA modification, mRNA translation, MHC class II, melanoma, T cells.

Disciplines :

Biotechnology

Author, co-author :

Seca, Christian ; Université de Liège - ULiège > Département de pharmacie

Language :

English

Title :

Perturbation of Codon-Specific mRNA Translation Reshapes MHC-II Tumor Antigen Presentation

Original title :

[en] Perturbation of Codon-Specific mRNA Translation Reshapes MHC-II Tumor Antigen Presentation

Defense date :

30 June 2025

Institution :

ULiège - University of Liège [GIGA], Belgium

Degree :

Doctorat en Sciences biomédicales et pharmaceutique

Promotor :

Marichal, Thomas ; Université de Liège - ULiège > GIGA > GIGA Immunobiology - Immunophysiology

Close, Pierre ; Université de Liège - ULiège > Département de pharmacie

Rapino, Francesca ; Université de Liège - ULiège > Département de pharmacie

President :

Chariot, Alain ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale

Jury member :

Michael Hoelzel; University of Bonn

Benoit Van Den Eynde; UCL - Catholic University of Louvain

Nguyen, Laurent ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques

Desmet, Christophe ; Université de Liège - ULiège > Département des sciences fonctionnelles (DSF)

Jerusalem, Guy ; Université de Liège - ULiège > Département des sciences cliniques > Oncologie

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since 23 July 2025

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