Tielens, S.* , Boutin Camille* , Huysseune, S.* , Thelen, N., Charlet-Briart, M., Reyskens, C., Oskera, L., Boutsen, A., Mateo Sanchez, S., Delacroix, L., Labedan Paul, Thiry, M., Malgrange, B., Chariot, A., Tissir Fadel, Creppe, C., Seuntjens, E., Laguesse, S.* , & Nguyen, L.*. (23 September 2024). Elp3 controls the maturation tempo of brain ependymal cells via NOTCH signaling [Poster presentation]. 25th Biennial meeting of the International Society for Developmental Neuroscience, Montpellier, France.  Editorial reviewed* These authors have contributed equally to this work. |
  | Li, C., Moro, S., Shostak, K., O'Reilly, F. J., Donzeau, M., Graziadei, A., McEwen, A. G., Desplancq, D., Poussin-Courmontagne, P., Bachelart, T., Fiskin, M., Berrodier, N., Pichard, S., Brillet, K., Orfanoudakis, G., Poterszman, A., Torbeev, V., Rappsilber, J., Davey, N. E., ... Zanier, K. (03 September 2024). Molecular mechanism of IKK catalytic dimer docking to NF-κB substrates. Nature Communications, 15 (1), 7692. doi:10.1038/s41467-024-52076-0 Peer Reviewed verified by ORBi |
 | Wathieu, C., Lavergne, A., Xu, X., Rolot, M., Nemazanyy, I., Shostak, K., El Hachem, N., Maurizy, C., Leemans, C., Close, P., Nguyen, L., Desmet, C., Tielens, S.* , Dewals, B. G.* , & Chariot, A.*. (2024). Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis. EMBO Journal. doi:10.1038/s44318-024-00184-4 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | El Hachem, N., Leclercq, M., Susaeta Ruiz, M., Vanleyssem, R., Shostak, K., Körner, P.-R., Capron, C., Martin Morales, L., RONCARATI, P., Lavergne, A., Blomme, A., Turchetto, S., Goffin, E., Thandapani, P., Tarassov, I., Nguyen, L., Pirotte, B., Chariot, A., Marine, J.-C., ... Close, P. (2024). Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nature Cell Biology. doi:10.1038/s41556-024-01439-2 Peer Reviewed verified by ORBi |
Tielens, S., Krusy, N., Stern, D., Van Hees, L., Reyskens, C., Laguesse, S., Chariot, A., & Nguyen, L. (28 September 2023). Unveiling the embryonic basis of neurodegeneration linked to impaired nucleocytoplasmic transport [Poster presentation]. Axon2023, Alicante, Spain. Editorial reviewed |
 | Petrellis, G., Rolot, M., Preure, A., Wathieu, C., Dougal, A., Chetty, A., Chariot, A., Horsnell, W., & Dewals, B. G. (01 May 2023). IL-4 RECEPTOR SIGNALING REGULATES LUNG MACROPHAGES DURING HELMINTH COINFECTION RESULTING IN ENHANCED GAMMAHERPESVIRUS PERMISSIVENESS. Journal of Immunology, 210 (1_Supplement), 72.36-72.36. doi:10.4049/jimmunol.210.supp.72.36 Peer Reviewed verified by ORBi |
Tielens, S., Krusy, N., Stern, D., Van Hees, L., Turchetto, S., Maurizy, C., Stoufflet, J., Laguesse, S., Chariot, A., & Nguyen, L. (06 September 2022). Unveilling the embryonic basis of neurodegeneration linked to impaired nucleocytoplasmic transport [Poster presentation]. GIGA day, Liège, Belgium. |
Lion, Q., Wen, X., Shostak, K., Vanleyssem, R., Close, P., Dejardin, E., & Chariot, A. (06 September 2022). ROLE OF THE tRNA-MODIFYING ENZYME ELONGATOR IN LIVER [Poster presentation]. GIGA DAY 2022. |
 | Chen, D., Nemazanyy, I., Peulen, O., Shostak, K., Xu, X., Tang, S. C., Wathieu, C., Turchetto, S., Tielens, S., Nguyen, L., Close, P., Desmet, C., Klein, S., Florin, A., Büttner, R., Petrellis, G., Dewals, B. G., & Chariot, A. (2022). Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization. EMBO Journal, 109353. doi:10.15252/embj.2021109353 Peer Reviewed verified by ORBi |
Wathieu, C., Tielens, S., Lavergne, A., Shostak, K., Rolot, M., El Hachem, N., Xu, X., Close, P., Nguyen, L., Desmet, C., Dewals, B. G., & CHARIOT, A. (10 May 2022). A role for the tRNA-modifying enzyme Elp3 in tuft cell differentiation and in the immune response in the intestine [Paper presentation]. Type 2 Immunity in Early Life Symposium, Liège, Belgium. |
Petrellis, G., Rolot, M., Preure, A., Wathieu, C., Dougall, A., Chetty, A., CHARIOT, A., Hornsell, W., & Dewals, B. G. (09 May 2022). IL-4rα-dependent Lung Macrophage Responses To Helminths Increase Permissiveness To Gammaherpesvirus Infection [Paper presentation]. Type 2 Immunity in Early Life, Liège, Belgium. |
  | Tang, S. C., Lion, Q., Peulen, O., Chariot, P., Lavergne, A., Mayer, A., Allepuz Fuster, P., Close, P., Klein, S., Florin, A., Büttner, R., Nemazanyy, I., Shostak, K., & Chariot, A. (29 January 2022). The E3 ligase COP1 promotes ERα signaling and suppresses EMT in breast cancer. Oncogene, 41, 173-190. doi:10.1038/s41388-021-02038-3 Peer Reviewed verified by ORBi |
Petrellis, G., Rolot, M., Preure, A., Wathieu, C., Dougall, A., Chetty, A., Chariot, A., Hornsell, W., & Dewals, B. G. (30 November 2021). Il-4rα-dependent Lung Macrophage Response To Helminth Increases Permissiveness To Gammaherpesvirus Infection [Paper presentation]. Belgian Society of Parasitology & Protistology Annual scientific meeting, Antwerp, Belgium. |
Petrellis, G., Rolot, M., Preure, A., Wathieu, C., Dougall, A., Chetty, A., Chariot, A., Horsnell, W., & Dewals, B. G. (November 2021). IL-4 receptor signaling regulates lung macrophages during helminth coinfection resulting in enhanced gammaherpesvirus permissiveness [Poster presentation]. Translational Immunology, Ghent, Belgium. |
 | Jeschke, J., Collignon, E., Al Wardi, C., Krayem, M., Bizet, M., Jia, Y., Garaud, S., Wimana, Z., Calonne, E., Hassabi, B., Morandini, R., Deplus, R., Putmans, P., Dube, G., Singh, N. K., Koch, A., Shostak, K., Rizzotto, L., Ross, R. L., ... Fuks, F. (June 2021). Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors. Nature Cancer, 2 (6), 611-628. doi:10.1038/s43018-021-00223-7 Peer reviewed |
 | Rosu, A., El Hachem, N., Rapino, F., Rouault-Pierre, K., Jorssen, J., SOMJA, J., Ramery, E., Thiry, M., Nguyen, L., Jacquemyn, M., Daelemans, D., Adams, C. M., Bonnet, D., Chariot, A., Close, P., Bureau, F., & Desmet, C. (2021). Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis. Journal of Experimental Medicine, 218 (3). doi:10.1084/jem.20200662 Peer reviewed |
 | Rapino, F.* , ZHOU, Z.* , RONCERO SANCHEZ, A. M.* , Joiret, M., Seca, C., El Hachem, N., Valenti, G., Latini, S., Shostak, K., Geris, L., Li, P., Huang, G., Mazzucchelli, G., Baiwir, D., Desmet, C., Chariot, A., Georges, M., & Close, P. (2021). Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nature Communications, 12 (1), 2170. doi:10.1038/s41467-021-22254-5 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Even, A.* , Morelli, G.* , Turchetto, S.* , Shilian, M., Le Bail, R., Laguesse, S., Krusy, N., Brisker, A., Brandis, A., Inbar, S., Chariot, A., Saudou, F., Dietrich, P., Dragatsis, I., Brone, B., Broix, L., Rigo, J.-M., Weil, M., & Nguyen, L. (2021). ATP-citrate lyase promotes axonal transport across species. Nature Communications, 12 (1), 5878. doi:10.1038/s41467-021-25786-y Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Shostak, K., Wathieu, C., Tielens, S., & Chariot, A. (2021). NF-κB Signaling in Ex-Vivo Mouse Intestinal Organoids. Methods in Molecular Biology, 2366, 283-292. doi:10.1007/978-1-0716-1669-7_17 Peer reviewed |
 | Lemaitre, P., Bai, Q., Legrand, C., Chariot, A., Close, P., Bureau, F., & Desmet, C. (2021). Loss of the Transfer RNA Wobble Uridine-Modifying Enzyme Elp3 Delays T Cell Cycle Entry and Impairs T Follicular Helper Cell Responses through Deregulation of Atf4. Journal of immunology (Baltimore, Md. : 1950). doi:10.4049/jimmunol.2000521 Peer reviewed |
 | Shostak, K., Jiang, Z., CHARLOTEAUX, B., Mayer, A., Habraken, Y., Tharun, L., Klein, S., Xu, X., Duong, H. Q., Vislovukh, A., Close, P., Florin, A., Rambow, F., Marine, J.-C., Büttner, R., & Chariot, A. (09 March 2020). The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage. Nature Communications, 11 (1). doi:10.1038/s41467-020-15003-7 Peer Reviewed verified by ORBi |
 | Balthazart, J., Blanpain, C., Bureau, F., Cani, P., Chariot, A., Drion, P., Engel, V., Hanson, J., de Kerchove d'Exaerde, A., Malgrange, B., Muraille, E., Nguyen, L., Servais, O., Seutin, V., & Tissir, F. (2019). L’expérimentation animale : toujours une nécessité pour la santé animale et humaine. Le Soir. |
 | DEROYER, C., CHARLIER, E., NEUVILLE, S., MALAISE, O., GILLET, P., KURTH, W., Chariot, A., MALAISE, M., & DE SENY, D. (2019). CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes. Cell Death and Disease. doi:10.1038/s41419-019-1377-8 Peer Reviewed verified by ORBi |
 | Freeman, S.* , Mateo Sánchez, S.* , Pouyo, R., Van Lerberghe, P.-B., Hanon, K., Thelen, N., Thiry, M., Morelli, G., Van Hees, L., Laguesse, S., Chariot, A., Nguyen, L., Delacroix, L.* , & Malgrange, B.*. (2019). Proteostasis is essential during cochlear development for neuron survival and hair cell polarity. EMBO Reports, 20 (9). doi:10.15252/embr.201847097 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Wathieu, C., Tielens, S., Rolot, M., Shostak, K., Close, P., Dewals, B. G., & CHARIOT, A. (16 October 2018). A role for the tRNA-modifying enzyme Elp3 in tuft cell differentiation and in the immune response in the intestine [Poster presentation]. EMBO workshop "From epigenome towards epitranscriptome in cell fate choice", Capri, Italy. |
 | Rapino, F., Delaunay, S., Rambow, F., Zhou, Z., Tharun, L., De Tullio, P., Sin, O., Shostak, K., Schmitz, S., Piepers, J., Guesquière, B., Karim, L., Charloteaux, B., Jamart, D., Florin, A., Lambert, C., RORIVE, A., JERUSALEM, G., Leucci, E., ... Close, P. (28 June 2018). Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature, 558, 605-609. doi:10.1038/s41586-018-0243-7 Peer Reviewed verified by ORBi |
 | Duong, H. Q., Nemazanyy, I., Rambow, F., Tang, S. C., Delaunay, S., Tharun, L., Florin, A., Büttner, R., VAN DAELE, D., Close, P., Marine, J.-C., Shostak, K., & Chariot, A. (2018). The endosomal protein CEMIP links Wnt signaling to MEK1-ERK1/2 activation in Selumetinib-resistant intestinal organoids. Cancer Research, 10.1158/0008-5472.CAN-17-3149. doi:10.1158/0008-5472.CAN-17-3149 Peer Reviewed verified by ORBi |
Laguesse, S., Huysseune, S., Boutin, C., Tielens, S., Franco, B., Mateo Sánchez, S., Delacroix, L., Boutin, P., Malgrange, B., CHARIOT, A., Goffinet, A., Tissir, F., Creppe, C., Seuntjens, E., & Nguyen, L. (13 June 2018). Loss of Elp3 induces postnatal hydrocephalus by inducing endoplasmic reticulum stress and dysregulation of Notch signaling [Poster presentation]. BSCDB spring meeting, Liege, Belgium. |
 | Bento-Abreu, A., Jager, G., Swinnen, B., Rué, L., Hendrickx, S., Jones, A., Staats, K. A., Taes, I., Eykens, C., Nonneman, A., Nuyts, R., Timmers, M., Silva, L., Chariot, A., Nguyen, L., Ravits, J., Lemmens, R., Cabooter, D., Van Den Bosch, L., ... Robberecht, W. (2018). Elongator subunit 3 (ELP3) modifies ALS through tRNA modification. Human Molecular Genetics, 27 (7), 1276-1289. doi:10.1093/hmg/ddy043 Peer Reviewed verified by ORBi |
 | Close, P., Debojit, B., Chariot, A., & Leidel, S. (2018). Dynamic regulation of tRNA modifications in Cancer. In Translational Epigenetics (édition revue et corrigée, pp. 163-186). Elsevier. doi:10.1016/B978-0-12-811022-5.00010-3 Peer reviewed |
 | Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique. |
 | Boerboom, A., Reusch, C., Pieltain, A., Chariot, A., & Franzen, R. (October 2017). KIAA1199: a novel regulator of MEK/ERK-induced Schwann cell dedifferentiation. Glia, 65 (10), 1682-1696. doi:10.1002/glia.23188 Peer Reviewed verified by ORBi |
 | Boerboom, A., Dion, V., CHARIOT, A., & Franzen, R. (2017). Molecular Mechanisms Involved in Schwann Cell Plasticity. Frontiers in Molecular Neuroscience. doi:10.3389/fnmol.2017.00038 Peer Reviewed verified by ORBi |
 | Rapino, F., Zhou, Z., Delaunay, S., Chariot, A., & Close, P. (2017). tRNA modification: is cancer having a wobble? Trends in Cancer, 3, 249-252. doi:10.1016/j.trecan.2017.02.004 Peer Reviewed verified by ORBi |
 | Laguesse, S., Close, P., Van Hees, L., Chariot, A., Malgrange, B., & Nguyen, L. (2017). Loss of Elp3 Impairs the Acetylation and Distribution of Connexin-43 in the Developing Cerebral Cortex. Frontiers in Cellular Neuroscience, 11, 122. doi:10.3389/fncel.2017.00122 Peer Reviewed verified by ORBi |
 | Delaunay, S., Rapino, F., Tharun, L., Zhou, Z., Heukamp, L., Termathe, M., Shostak, K., Klevernic, I., Florin, A., Desmecht, H., Desmet, C., Nguyen, L., Leiden, S. A., Willis, A. E., Buettner, R., Chariot, A., & Close, P. (October 2016). ELP3 links tRNA modification to IRES-dependent translation of LEF-1 to promote metastasis in breast cancer. Journal of Experimental Medicine, 213, 2503-2523. doi:10.1084/jem.20160397 Peer Reviewed verified by ORBi |
Tielens, S., Huysseune, S., Godin, J., CHARIOT, A., Malgrange, B., & Nguyen, L. (12 May 2016). Elongator controls cortical interneuron migration by regulating actomyosin dynamics [Poster presentation]. ISDN, France. |
Delaunay, S., Rapino, F., Tharun, L., Zhou, Z., Heukamp, L., Termathe, M., Shostak, K., Klevernic, I., Florin, A., Desmecht, H., Nguyen, L., Leidel, S., Willis, A., Chariot, A., & Close, P. (May 2016). tRNA modification: Elogator sustains Breast cancer metastasis [Paper presentation]. Invitation pour une présentation au Stem Cell Institute - Cambridge University, Cambridge, United Kingdom. |
 | Boerboom, A., Dion, V., Pieltain, A., Shostak, K., Chariot, A., & Franzen, R. (May 2016). KIAA1199 links ErbB signalling to Schwann cell development and plasticity [Poster presentation]. Gordon seminar + conference Myelin. |
 | Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Delrez, S., Chariot, A., Nguyen, L., & Malgrange, B. (25 January 2016). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. GIGA-Day. |
Delaunay, S., Rapino, F., Zhou, Z., Shostak, K., LADANG, A., Chariot, A., & Close, P. (25 January 2016). tRNA modification: Elogator promotes metastasis in breast cancer [Paper presentation]. GIGA-DAY 2016, Liège, Belgium. |
 | Dion, V., Boerboom, A., Pieltain, A., Chariot, A., & Franzen, R. (2016). Remyelination in the adult central nervous system: A possible role for Elongator [Poster presentation]. Gordon Research Conferences - Myelin. |
 | Göktuna, S., Shostak, K., Chau, T.-L., Heukamp, L., Hennuy, B., Duong, H. Q., LADANG, A., Close, P., Klevernic, I., Olivier, F., Florin, A., Ehx, G., Baron, F., Vandereyken, M., Rahmouni, S., Vereecke, L., van Loo, G., Büttner, R., Greten, F., & Chariot, A. (2016). The Prosurvival IKK-Related Kinase IKK« Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine. Cancer Research, 76, 2587-99. doi:10.1158/0008-5472.CAN-15-1473 Peer Reviewed verified by ORBi |
 | Tielens, S.* , Huysseune, S.* , Godin, J. D., Chariot, A., Malgrange, B., & Nguyen, L. (2016). Elongator controls cortical interneuron migration by regulating actomyosin dynamics. Cell Research. doi:10.1038/cr.2016.112 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Delrez, S., Chariot, A., Nguyen, L., & Malgrange, B. (23 November 2015). UNRAVELLING THE ROLES OF LYSINE ACETYLATION BY ELP3 DURING INNER EAR DEVELOPMENT [Poster presentation]. Belgian Society for Cell and Developmental Biology (BSCDB). |
 | LADANG, A.* , Rapino, F.* , Heukamp, L., Tharun, L., Shostak, K., Hermand, D., Delaunay, S., Klevernic, I., Jiang, Z., Jacques, N., Jamart, D., Migeot, V., Florin, A., Göktuna, S., Malgrange, B., Samson, O., Nguyen, L., Buettner, R., Close, P., & Chariot, A. (16 November 2015). Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine. Journal of Experimental Medicine, 212 (12), 2057-75. doi:10.1084/jem.20142288 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
Czajkowski, A., Chariot, A., Delacroix, L., & Malgrange, B. (November 2015). Unravelling Cemip expression and functions in the auditory portion of the inner ear [Poster presentation]. BSCDB - BELGIAN SOCIETY FOR CELL AND DEVELOPMENTAL BIOLOGY. |
 | Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Delrez, S., Chariot, A., Nguyen, L., & Malgrange, B. (06 June 2015). UNRAVELLING THE ROLES OF LYSINE ACETYLATION BY ELP3 DURING INNER EAR DEVELOPMENT [Poster presentation]. Belgian Society for Cell and Developmental Biology (BSCDB). |
 | Shostak, K., & Chariot, A. (June 2015). EGFR and NF-kB: partners in cancer. Trends in Molecular Medicine, 21, 385-393. doi:10.1016/j.molmed.2015.04.001 Peer Reviewed verified by ORBi |
 | Czajkowski, A., Chariot, A. (Other coll.), Delacroix, L. (Other coll.), & Malgrange, B. (Other coll.). (29 May 2015). Unravelling Cemip expression and functions in the auditory portion of the inner ear [Poster presentation]. BSCDB - BELGIAN SOCIETY FOR CELL AND DEVELOPMENTAL BIOLOGY. |
Czajkowski, A., Chariot, A., Delacroix, L., & Malgrange, B. (22 May 2015). Unravelling Cemip expression and functions in the auditory portion of the inner ear [Poster presentation]. 11th meeting of the Belgian Neuroscience Society, Mons, Belgium. |
 | Boerboom, A., Dion, V., Pieltain, A., Chariot, A., & Franzen, R. (May 2015). KIAA1199 is involved in Schwann cell survival and differentiation [Poster presentation]. Belgian Society for Neuroscience 2015. |
Delaunay, S., Rapino, F., Zhou, Z., LADANG, A., Shostak, K., Chariot, A., & Close, P. (09 March 2015). Elongator: mcm5s2 modification fosters breast cancer metastasis [Paper presentation]. MRC toxicology meeting, Leicester, United Kingdom. |
 | Delaunay, S., Rapino, F., Heukamp, L., LADANG, A., Jiang, Z., Nguyen, L., Buettner, R., Chariot, A., & Close, P. (March 2015). Elongator promotes breast cancer metastasis [Poster presentation]. EMBO meeting, Frontiers in stem cells, Heidelberg, Germany. |
 | Mateo Sanchez, S., Delacroix, L., Freeman, S., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (27 January 2015). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. GIGA-Day. |
 | Lamour, V., Henry, A., Kroonen, J., Nokin, M.-J., von Marschall, Z., Fisher, L., Chau, T.-L., Chariot, A., Sanson, M., Delattre, J.-Y., Turtoi, A., Peulen, O., Rogister, B., Castronovo, V., & Bellahcene, A. (2015). Targeting osteopontin suppresses glioblastoma stem-like cell character and tumorigenicity in vivo. International Journal of Cancer. doi:10.1002/ijc.29454 Peer Reviewed verified by ORBi |
Creppe, C., Laguesse, S., Nedialkova, D., Prevot, P.-P., Borgs, L., Huysseune, S., Franco, B., Duysens, G., Kruzy, N., Lee, G., Thelen, N., Thiry, M., Close, P., Chariot, A., Leidel, S., Godin, J., & Nguyen, L. (2015). A dynamic Unfolded Protein Response controls cortical neurogenesis [Poster presentation]. FENS Featured Regional Meeting 2015, Thessaloniki, Greece. |
 | Laguesse, S.* , Creppe, C.* , Nedialkova, D., Prevot, P.-P., Borgs, L., Huysseune, S., Franco, B., Duysens, G., Krusy, N., Lee, G., Thelen, N., Thiry, M., Close, P., Chariot, A., Malgrange, B., Leidel, S., Godin, J., & Nguyen, L. (2015). A dynamic unfolded protein response contributes to the control of cortical neurogenesis. Developmental Cell, 35, 553-567. doi:10.1016/j.devcel.2015.11.005 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Chau, T.-L., Göktuna, S., Rammal, A., Casanova Bustos, T. R., Duong, H. Q., GATOT, J.-S., Close, P., Dejardin, E., Desmecht, D., Shostak, K., & Chariot, A. (2015). A role for APPL1 in tlr3/4-dependent TBK1 and IKKε activation in macrophages. Journal of Immunology. doi:10.4049/jimmunol.1401614 Peer Reviewed verified by ORBi |
Dion, V., Boerboom, A., Pieltain, A., Chariot, A., & Franzen, R. (2015). Role of Elongator in central nervous system remyelination [Poster presentation]. Belgian Society for Neuroscience 2015. |
Creppe, C., Laguesse, S., Nedialkova, D., Prevot, P.-P., Borgs, L., Huysseune, S., Franco, B., Duysens, G., Krusy, N., Lee, G., Thelen, N., Thiry, M., Close, P., CHARIOT, A., Malgrange, B., Leidel, S., Godin, J., & Nguyen, L. (2015). A dynamic Unfolded Protein Response controls cortical neurogenesis [Poster presentation]. BSCDB meeting "Neural stem cells and cortical development", Liege, Belgium. |
Tielens, S., Huysseune, S., Malgrange, B., CHARIOT, A., Godin, J., & Nguyen, L. (08 July 2014). Deciphering the role of Elp3 in interneuron migration in cortical development [Poster presentation]. FENS, Milano, Italy. |
 | Delaunay, S., Heukamp, L., Zhou, Z., Shostak, K., LADANG, A., Jiang, Z., Nguyen, L., Chariot, A., & Close, P. (08 May 2014). Elongator drives breast cancer initiation and metastasis formation [Poster presentation]. ENBDC meeting 2014, Weggis, Switzerland. |
 | Shostak, K.* , Patrascu, F.* , Göktuna, S., Close, P., Borgs, L., Nguyen, L., Olivier, F., Rammal, A., Brinkhaus, H., Bentires-Alj, M., Marine, J.-C., & Chariot, A. (May 2014). MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradation. Cell Death and Differentiation, 5 (21), 811-24. doi:10.1038/cdd.2014.2 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Volvert, M.-L., Prevot, P.-P., Close, P., Laguesse, S., Pirotte, S., Hemphill, J., Rogister, F., Krusy, N., SACHELI, R., MOONEN, G., Deiters, A., Merkenschlager, M., CHARIOT, A., Malgrange, B., Godin, J., & Nguyen, L. (May 2014). MicroRNA Targeting of CoREST controls polarization of migrating cortical neurons. Cell Reports, 7 (4), 1168-83. doi:10.1016/j.celrep.2014.03.075 Peer Reviewed verified by ORBi |
 | Mateo Sanchez, S., Delacroix, L., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (27 January 2014). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Paper presentation]. GIGA-Day. |
 | Shostak, K., Zhang, X., Hubert, P., Göktuna, S., Jiang, Z., Klevernic, I., Hildebrand, J., Roncarati, P., Hennuy, B., Ladang, A., SOMJA, J., Gothot, A., Close, P., Delvenne, P., & Chariot, A. (2014). NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Nature Communications, 5, 5232. doi:10.1038/ncomms6232 Peer Reviewed verified by ORBi |
| Mateo Sanchez, S., Delacroix, L., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (2014). Unravelling the roles of lysine acetyl-transferase activity of Elongator complex during inner ear development [Paper presentation]. Inner Ear Biology meeting (IEB). |
 | Göktuna, S., Canli, O., Bollrath, J., Fingerle, A. A., Horst, D., Diamanti, M. A., Pallangyo, C., Bennecke, M., Nebelsiek, T., Mankan, A. K., Lang, R., Artis, D., Hu, Y., Patzelt, T., Ruland, J., Kirchner, T., Taketo, M. M., Chariot, A., Arkan, M. C., & Greten, F. R. (2014). IKKalpha promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells. Cell Reports, 7 (6), 1914-25. doi:10.1016/j.celrep.2014.05.006 Peer Reviewed verified by ORBi |
 | Stellzig, J., Chariot, A., Shostak, K., Göktuna, S., Renner, F., Acker, T., Pagenstecher, A., & Schmitz, M. (11 November 2013). Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways. Observatoire (L'), e79. doi:10.1038/oncsis.2013.42 Peer reviewed |
| Mateo Sanchez, S., Delacroix, L., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (18 October 2013). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. Belgian Society for Cell and Developmental Biology (BSCDB). |
Ladang, A., Heukamp, L., Buettner, R., Jiang, Z., Jamart, D., Close, P., & Chariot, A. (18 September 2013). Elp3 is required for initiation of colon cancer [Poster presentation]. Experimental models of human diseases. |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (June 2013). p27(Kip1) as a master regulator of cortical neuron migration [Paper presentation]. EMBO fellow meeting. |
 | Mateo Sanchez, S., Delacroix, L., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (31 May 2013). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. BSN Congress. |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., MOONEN, G., Malgrange, B., Chariot, A., Métin, C., Besson, A., & Nguyen, L. (March 2013). p27(Kip1) as a Microtubule-Associated Protein that Promotes Microtubule Polymerization during Neuron Migration [Paper presentation]. Microtubule cytoskeleton in development and disease conference. |
Mateo Sanchez, S., Delacroix, L., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (28 January 2013). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. GIGA-DAY. |
Delacroix, L., Mateo Sanchez, S., Nguyen, L., Chariot, A., & Malgrange, B. (2013). Unravelling the role of lysine acetylation by Elongator complex during inner ear development [Poster presentation]. Molecular Biology of Hearing and Deafness Conference, San Francisco, United States - California. |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (2013). p27(Kip1) as a master regulator of cortical neuron migration [Poster presentation]. annual meeting of the american society for cell biology. |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (2013). p27 Is a Microtubule-Associated Protein that Promotes Microtubule Polymerization during Neuron Migration [Poster presentation]. annual meeting of the belgium society for neuroscience. |
 | Boerboom, A., Chaballe, L., Close, P., Schoenen, J., Chariot, A., & Franzen, R. (October 2012). Acetylation and Wallerian degeneration [Poster presentation]. Belgian Brain Congress 2012. |
 | Close, P., Gillard, M., Ladang, A., Jiang, Z., Papuga, J., Hawkes, N., Nguyen, L., CHAPELLE, J.-P., Bouillenne, F., Svejstrup, J., Fillet, M., & Chariot, A. (2012). DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator. Journal of Biological Chemistry. doi:10.1074/jbc.M112.402727 Peer Reviewed verified by ORBi |
Mateo Sanchez, S., Delacroix, L., Laguesse, S., Huysseune, S., Chariot, A., Nguyen, L., & Malgrange, B. (04 May 2012). Unravelling the roles of lysine acetylation by Elp3 during inner ear development [Poster presentation]. GIGA-DAY. |
 | Close, P., East, P., Svejstrup, B., Hartmann, H., Heron, M., Maslen, S., Chariot, A., Söding, J., Skehel, M., & Svejstrup, J. (2012). DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation. Nature. doi:10.1038/nature10925 Peer Reviewed verified by ORBi |
 | Ortis, F., Miani, M., Colli, M., Cunha, D., Gurzov, E., Allagnat, F., Chariot, A., & Eizirik, D. L. (05 April 2012). Differential usage of NF-kB activating signals by IL-1b and TNF-a in pancreatic beta cells. FEBS Letters, 586, 984-989. Peer Reviewed verified by ORBi |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (2012). p27(Kip1) Is a Microtubule-Associated Protein that Promotes Microtubule Polymerization during Neuron Migration [Poster presentation]. Federation of European Neuroscience Societies (FENS). |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (2012). p27(Kip1) as a master regulator of cortical neuron migration [Poster presentation]. EMBO Workshop on Cortical interneurons in health and disease. |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (2012). p27(Kip1) as a master regulator of cortical neuron migration [Poster presentation]. EMBO Conference Series Microtubules Structure, Regulation and Functions. |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (2012). Cortical interneurons tangential migration : p27(Kip1) as a novel master regulator [Poster presentation]. Cortical development conference. |
 | Godin, J.* , Thomas, N.* , Laguesse, S.* , Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Chariot, A., Metin, C., Besson, A., & Nguyen, L. (2012). p27(Kip1) Is a Microtubule-Associated Protein that Promotes Microtubule Polymerization during Neuron Migration. Developmental Cell, 23 (4), 729-44. doi:10.1016/j.devcel.2012.08.006 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Ganeff, C., Remouchamps, C., Boutaffala, L., Benezech, C., Galopin, G., Vandepaer, S., Bouillenne, F., Ormenese, S., Chariot, A., Schneider, P., Caamano, J., Piette, J., & Dejardin, E. (30 November 2011). Induction of the Alternative NF-{kappa}B Pathway by Lymphotoxin {alpha}{beta} (LT{alpha}{beta}) Relies on Internalization of LT{beta} Receptor. Molecular and Cellular Biology, 21, 4319-4334. doi:10.1128/MCB.05033-11 Peer Reviewed verified by ORBi |
 | Shostak, K., & Chariot, A. (26 July 2011). NF-kB, stem cells and breast cancer: the links get stronger. Breast Cancer Research, 13 (4), 214. doi:10.1186/bcr2886 Peer Reviewed verified by ORBi |
Godin, J., Thomas, N., Laguesse, S., Malinouskaya, L., Close, P., MALAISE, O., Purnelle, A., Raineteau, O., Campbell, K., Fero, M., Moonen, G., Malgrange, B., Métin, C., Chariot, A., & Nguyen, L. (June 2011). p27(Kip1) as a master regulator of cortical neuron migration [Paper presentation]. cancéropole - Toulouse - France. |
Close, P., Gillard, M., Ladang, A., Jiang, Z., Fillet, M., & Chariot, A. (12 March 2011). DERP6 and C3orf75 regulate the invasive potential of melanoma cells as subunits of the elongator complex [Poster presentation]. Stem Cells, Cancer and Metastasis, United States. |
 | Chaballe, L., Close, P., SEMPELS, M., DELSTANCHE, S., FANIELLE, J., Moons, L., Carmeliet, P., Schoenen, J., Chariot, A., & Franzen, R. (March 2011). Involvement of placental growth factor in Wallerian degeneration. Glia, 59 (3), 379-396. doi:10.1002/glia.21108 Peer Reviewed verified by ORBi |
| Chaballe, L., Close, P., Sempels, M., Delstanche, S., Fanielle, J., Moons, L., Carmeliet, P., Schoenen, J., Chariot, A., & Franzen, R. (September 2010). Involvement of Placental growth factor in Wallerian degeneration [Poster presentation]. Belgian Brain Congress, Bruxelles, Belgium. |
 | Keutgens, A., Shostak, K., Close, P., Zhang-Shao, X., Hennuy, B., Aussems, M., Chapelle, J.-P., Viatour, P., Gothot, A., Fillet, M., & Chariot, A. (August 2010). The repressing function of the oncoprotein BCL-3 requires CtBP while its polyubiquitination and degradation involve the E3 ligase TBLR1. Molecular and Cellular Biology, 30, 4006-4021. doi:10.1128/MCB.01600-09 Peer Reviewed verified by ORBi |
 | Close, P., Creppe, C., Gillard, M., LADANG, A., Chapelle, J.-P., Nguyen, L., & Chariot, A. (April 2010). The emerging role of lysine acetylation of non-nuclear proteins. Cellular and Molecular Life Sciences, 67 (8), 1255-1264. doi:10.1007/s00018-009-0252-7 Peer Reviewed verified by ORBi |
 | creppe, C., malinouskaya, L., Volvert, M.-L., Close, P., Laguesse, S., Gillard, M., Chariot, A., & Nguyen, L. (2010). Elongator orchestrates cerebral cortical neurogenesis. MS. Medecine Sciences. doi:10.1051/medsci/2010262135 |
 | Heng, J., Chariot, A., & Nguyen, L. (2010). Molecular Layers underlying cytoskeletal remodelling during cortical development. Trends in Neurosciences, 33, 38-47. doi:10.1016/j.tins.2009.09.003 Peer Reviewed verified by ORBi |
 | Keutgens, A., Zhang-Shao, X., Shostak, K., Robert, I., Olivier, S., Vanderplasschen, A., Chapelle, J.-P., Viatour, P., Merville, M.-P., Bex, F., Gothot, A., & Chariot, A. (2010). BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1. Journal of Biological Chemistry, 285 (33), 25831–25840. doi:10.1074/jbc.M110.112128 Peer Reviewed verified by ORBi |
Ganeff, C., Galopin, G., Remouchamps, C., Benezech, C., Boutaffala, L., de trez, C., Bouillenne, F., Ormenese, S., CHARIOT, A., Norris, P., Ware, C., Schneider, P., Caamano, J., Piette, J., & Dejardin, E. (January 2010). TNFL–Induced p100 processing (TIPP) relies on the internalization of the cognate TNFR [Paper presentation]. Inflammation 2010, Luxembourg, Luxembourg. |
 | Nguyen, L., Humbert, S., Saudou, F., & Chariot, A. (January 2010). Elongator - an emerging role in neurological disorders. Trends in Molecular Medicine, 16, 1-6. doi:10.1016/j.molmed.2009.11.002 Peer Reviewed verified by ORBi |
| Charlier, E., Condé, C., Zhang, J., Deneubourg, L., Di Valentin, E., Rahmouni, S., Chariot, A., Agostinis, P., Pang, P.-C., Haslam, S., Dell, A., Penninger, J., Erneux, C., Piette, J., & Gloire, G. (2010). SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity. Leukemia. doi:10.1038/leu.2010.9 Peer Reviewed verified by ORBi |
 | Chariot, A. (August 2009). The NF-κ B-independent functions of IKK subunits in immunity and cancer. Trends in Cell Biology, 19, 404-413. doi:10.1016/j.tcb.2009.05.006 Peer Reviewed verified by ORBi |
 | Robert, I., Aussems, M., Keutgens, A., Zhang-Shao, X., Hennuy, B., Viatour, P., Vanstraelen, G., Merville, M.-P., Chapelle, J.-P., de Leval, L., LAMBERT, F., Dejardin, E., Gothot, A., & Chariot, A. (02 April 2009). Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-κB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes. Oncogene, 28 (13), 1626-1638. doi:10.1038/onc.2009.6 Peer Reviewed verified by ORBi |
 | Creppe, C., Malinouskaya, L., Volvert, M.-L., Gillard, M., Close, P., Malaise, O., Laguesse, S., Cornez, I., Rahmouni, S., Ormenese, S., Belachew, S., Malgrange, B., Chapelle, J.-P., Siebenlist, U., Moonen, G., Chariot, A., & Nguyen, L. (06 February 2009). Elongator controls the migration and differentiation of cortical neurons through acetylation of a tubulin. Cell, 136, 551-564. doi:10.1016/j.cell.2008.11.043 Peer Reviewed verified by ORBi |
 | Claudio, E., Sonder, S. U., Saret, S., Carvalho, G., Ramalingam, T. R., Wynn, T. A., Chariot, A., Garcia-Perganeda, A., Leonardi, A., Paun, A., Chen, A., Ren, N. Y., Wang, H., & Siebenlist, U. (2009). The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation. Journal of Immunology, 182, 1617-1639. doi:10.4049/jimmunol.182.3.1617 Peer Reviewed verified by ORBi |
 | Ortis, F., Pirot, P., Naamane, N., Kreins, A. Y., Rasschaert, J., Moore, F., Theatre, E., Verhaeghe, C., Magnusson, N. E., Chariot, A., Orntoft, T. F., & Eizirik, D. L. (July 2008). Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells. Diabetologia, 51, 1213-1225. doi:10.1007/s00125-008-0999-7 Peer Reviewed verified by ORBi |
 | Cornez, I., Creppe, C., Gillard, M., Hennuy, B., Chapelle, J.-P., Dejardin, E., Merville, M.-P., Close, P., & Chariot, A. (June 2008). Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells. Biochemical Pharmacology, 75, 2122-2134. doi:10.1016/j.bcp.2008.03.006 Peer Reviewed verified by ORBi |
 | Verstrepen, L., Bekaert, T., Chau, T.-L., Tavernier, J., Chariot, A., & Beyaert, R. (2008). TLR-4, IL-1R and TNF-R signaling to NF-kB: variations on a common theme. Cellular and Molecular Life Sciences, 65, 2964-2978. doi:10.1007/s00018-008-8064-8 Peer Reviewed verified by ORBi |
 | Jonville, M., Kodja, H., Humeau, L., Fournel, J., Chariot, A., De Mol, P., Cao, M.-C., Angenot, L., & Frederich, M. (2008). Evaluation of medicinal plants from Reunion Island for antimalarial and cytotoxic activities. Planta Medica, 74 (9), 1002-1002. Peer Reviewed verified by ORBi |
 | Chau, T.-L., Gioia, R., GATOT, J.-S., Patrascu, F. A., Carpentier, I., Chapelle, J.-P., O'Neill, L., Beyaert, R., Piette, J., & Chariot, A. (2008). Are the IKKs and IKK-related kinases TBK1 and IKK-ε similarly activated ? Trends in Biochemical Sciences, 33, 171-180. doi:10.1016/j.tibs.2008.01.002 Peer Reviewed verified by ORBi |
Gioia, R., GATOT, J.-S., Chau, T.-L., Warnier, M., Chapelle, J.-P., Piette, J., Dejardin, E., & Chariot, A. (December 2007). Insight into the TBK1/IKK-dependent signalling pathways required in innate immunity through identification of the TANK/I-TRAF interactome [Poster presentation]. Journée Télévie, ULB GOsselies, Belgium. |
 | GATOT, J.-S., Gioia, R., Chau, T.-L., Patrascu, F. A., Warnier, M., Close, P., Chapelle, J.-P., Muraille, E., Brown, K., Siebenlist, U., Piette, J., Dejardin, E., & Chariot, A. (26 October 2007). Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKK epsilon-dependent lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. Journal of Biological Chemistry, 282 (43), 31131-31146. doi:10.1074/jbc.M701690200 Peer Reviewed verified by ORBi |
 | Lambert, C., Oury, C., Dejardin, E., Chariot, A., Piette, J., Malaise, M., Merville, M.-P., & Franchimont, N. (September 2007). Further insights in the mechanisms of interleukin-1beta stimulation of osteoprotegerin in osteoblast-like cells. Journal of Bone and Mineral Research, 22 (9), 1350-1361. doi:10.1359/jbmr.070508 Peer Reviewed verified by ORBi |
 | Gloire, G., Horion, J., El Mjiyad, N., Bex, F., Chariot, A., Dejardin, E., & Piette, J. (20 July 2007). Promoter-dependent effect of IKK alpha on NF-kappa B/p65 DNA binding. Journal of Biological Chemistry, 282 (29), 21308-21318. doi:10.1074/jbc.M610728200 Peer Reviewed verified by ORBi |
 | Jokhadze, M., Eristavi, L., Kutchukhidze, J., Chariot, A., Angenot, L., Tits, M., Jansen, O., & Frederich, M. (July 2007). In vitro cytotoxicity of some medicinal plants from Georgian amaryllidaceae. Phytotherapy Research, 21 (7), 622-624. doi:10.1002/ptr.2130 Peer Reviewed verified by ORBi |
 | Lambert, F., Heimann, P., Herens, C., Chariot, A., & Bours, V. (July 2007). Consultations in molecular diagnostics - A case of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia with a rare FIP1L1 breakpoint. Journal of Molecular Diagnostics, 9 (3), 414-419. doi:10.2353/jmoldx.2007.060196 Peer Reviewed verified by ORBi |
 | Verhaeghe, C., Remouchamps, C., Hennuy, B., Vanderplasschen, A., Chariot, A., Tabruyn, S. P., Oury, C., & Bours, V. (15 June 2007). Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. Biochemical Pharmacology, 73 (12), 1982-1994. doi:10.1016/j.bcp.2007.03.019 Peer Reviewed verified by ORBi |
Creppe, C., Close, P., Cornez, I., Rahmouni, S., Merville, M.-P., Chapelle, J.-P., Nusgens, C., Deroanne, C., & Chariot, A. (March 2007). A role for the transcriptional complex elongator in cell migration and spreading [Poster presentation]. Colloque "Chromatin Dynamics and Epigenetics" Société belge de biologie cellulaire et du développement, Liège, Belgium. |
GATOT, J.-S., Gioia, R., Chau, T.-L., Warnier, M., Chapelle, J.-P., Merville, M.-P., Brown, K., Siebenlist, U., Muraille, E., Dejardin, E., Piette, J., & Chariot, A. (March 2007). Polyubiquitination of the scaffold protein tank/I-traf: implications for the TLR-mediated signalling pathways [Poster presentation]. Colloque "Chromatin Dynamics and Epigenetics" Société belge de biologie cellulaire et du développement, Liège, Belgium. |
 | Keutgens, A., Robert, I., Viatour, P., & Chariot, A. (30 October 2006). Deregulated NF-kappa B activity in haematological malignancies. Biochemical Pharmacology, 72 (9), 1069-1080. doi:10.1016/j.bcp.2006.06.011 Peer Reviewed verified by ORBi |
 | Chariot, A. (30 October 2006). 20 years of NF-kappa B. Biochemical Pharmacology, 72 (9), 1051-1053. doi:10.1016/j.bcp.2006.08.023 |
 | Benoit, V., de Moraes, E., Dar, N. A., Taranchon, E., Bours, V., Hautefeuille, A., Taniere, P., Chariot, A., Scoazec, J. Y., Gallo, C. V. D., Merville, M.-P., & Hainaut, P. (21 September 2006). Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappaB. Oncogene, 25 (42), 5708-5718. doi:10.1038/sj.onc.1209579 Peer Reviewed verified by ORBi |
 | Close, P., Hawkes, N., Cornez, I., Creppe, C., Lambert, C. A., Rogister, B., Siebenlist, U., Merville, M.-P., Slaugenhaupt, S. A., Bours, V., Svejstrup, J. Q., & Chariot, A. (May 2006). Transcription impairment and cell migration defects in elongator-depleted cells: Implication for familial dysautonomia. Molecular Cell, 22 (4), 521-531. doi:10.1016/j.molcel.2006.04.017 Peer Reviewed verified by ORBi |
 | Olivier, S., Close, P., Castermans, E., de Leval, L., Tabruyn, S., Chariot, A., Malaise, M., Merville, M.-P., Bours, V., & Franchimont, N. (May 2006). Raloxifene-induced myeloma cell apoptosis: a study of nuclear factor-kappaB inhibition and gene expression signature. Molecular Pharmacology, 69 (5), 1615-1623. doi:10.1124/mol.105.020479 Peer Reviewed verified by ORBi |
 | Jansen, O., Akhmedjanova, V., Angenot, L., Balansard, G., Chariot, A., Ollivier, E., Tits, M., & Frederich, M. (21 April 2006). Screening of 14 alkaloids isolated from Haplophyllum A. Juss. for their cytotoxic properties. Journal of Ethnopharmacology, 105 (1-2), 241-245. doi:10.1016/j.jep.2005.11.001 Peer Reviewed verified by ORBi |
Chariot, A., Hawkes, N., Cornez, I., Creppe, C., Lambert, C., Rogister, B., Siebenlist, U., Merville, M., Slaugenhaupt, S., Bours, V., Svejstrup, J., & Close, P. (23 March 2006). News from a lost friend: IKAP depletion causes defective transcript elongation of genes involved in cell migration throught NFkB-independent meachanisms: implications for familial dysautonomia [Poster presentation]. Keystone Symposia, Banff, Alberta, Canada. |
 | Gloire, G., Charlier, E., Rahmouni, S., Volanti, C., Chariot, A., Erneux, C., & Piette, J. (2006). Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress. Oncogene, 25 (40), 5485-94. doi:10.1038/sj.onc.1209542 Peer Reviewed verified by ORBi |
Lambert, F., Schioppa, A., Castermans, S., Lopez, M.-J., Chariot, A., & Bours, V. (2006). Accurate genotyping of the V617F janus kinase (JAK) 2 mutation combining ARMS PCR and capillary electrophoresis. Acta Clinica Belgica, 61 (2, MAR-APR), 108. Peer Reviewed verified by ORBi |
 | Robe, P., Martin, D., Albert, A., Deprez, M., Chariot, A., & Bours, V. (2006). A phase 1-2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668]. BMC Cancer, 6, 29. doi:10.1186/1471-2407-6-29 Peer Reviewed verified by ORBi |
 | Bonif, M., Meuwis, M.-A., Close, P., Benoit, V., Heyninck, K., Chapelle, J.-P., Bours, V., Merville, M.-P., Piette, J., Beyaert, R., & Chariot, A. (2006). TNFa and IKKb-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKg and NF-kB activation. Biochemical Journal, 394, 593-603. doi:10.1042/BJ20051659 Peer Reviewed verified by ORBi |
Close, P., Hawkes, N., Cornez, I., Creppe, C., Lambert, C., Rogister, B., Siebenlist, U., Merville, M., Slaugnhaupt, S., Bours, V., Svejstrup, J., & Chariot, A. (15 November 2005). Elongator depletion causes defective transcript elongation of genes that regulate cell motility [Poster presentation]. Chromatin structure and function, Nassau, Bahamas. |
Olivier, S., Close, P., Castermans, E., de Leval, L., Tabruyn, S., Chariot, A., Malaise, M., Merville, M.-P., Bours, V., & Franchimont, N. (September 2005). SERMs-induced myeloma cell apoptosis: A study of NF-kappa B inhibition and gene expression signature. Journal of Bone and Mineral Research, 20 (9, Suppl. 1), 213. |
 | Lechanteur, C., Jacobs, N., Greimers, R., Benoit, V., Deregowski, V., Chariot, A., Merville, M.-P., & Bours, V. (03 March 2005). Low daunomycin concentrations protect colorectal cancer cells from hypoxia-induced apoptosis. Oncogene, 24 (10), 1788-1793. doi:10.1038/sj.onc.1208436 Peer Reviewed verified by ORBi |
 | Franchimont, N., Lambert, C., Huynen, P., Ribbens, C., Relic, B., Chariot, A., Bours, V., Piette, J., Merville, M.-P., & Malaise, M. (2005). Interleukin-6 receptor shedding is enhanced by interleukin-1beta and tumor necrosis factor alpha and is partially mediated by tumor necrosis factor alpha-converting enzyme in osteoblast-like cells. Arthritis and Rheumatism, 52 (1), 84-93. doi:10.1002/art.20727 Peer Reviewed verified by ORBi |
 | Viatour, P., Merville, M.-P., Bours, V., & Chariot, A. (January 2005). Phosphorylation of NF-kappa B and I kappa B proteins: implications in cancer and inflammation [letter to the editor]. Trends in Biochemical Sciences, 30 (1), 43-52. doi:10.1016/j.tibs.2004.11.009 Peer Reviewed verified by ORBi |
 | Viatour, P., Merville, M.-P., Bours, V., & Chariot, A. (December 2004). Protein phosphorylation as a key mechanism for the regulation of BCL-3 activity. Cell Cycle, 3 (12), 1498-1501. doi:10.4161/cc.3.12.1328 Peer Reviewed verified by ORBi |
 | Viatour, P., Dejardin, E., Warnier, M., Lair, F., Claudio, E., Bureau, F., Marine, J. C., Merville, M.-P., Maurer, U., Green, D., Piette, J., Siebenlist, U., Bours, V., & Chariot, A. (08 October 2004). GSK3-Mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity. Molecular Cell, 16 (1), 35-45. doi:10.1016/j.molcel.2004.09.004 Peer Reviewed verified by ORBi |
 | Adam, E., Quivy, V., Bex, F., Chariot, A., Collette, Y., Vanhulle, C., Haterte, S., Goffin, V., Nguyen, T. L.-A., Gloire, G., Carrard, G., Friguet, B., de Launoit, Y., Burny, A., Bours, V., Piette, J., & Van Lint, C. (August 2004). Erratum: Potentiation of tumor necrosis factor-induced NF-κb activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of IκBα (Molecular and Cellular Biology (2003) 23, 17 (6200-6209)). Molecular and Cellular Biology, 24 (15), 6890. doi:10.1128/MCB.24.15.6890.2004 |
 | Benoit, V., Relic, B., de Leval, L., Chariot, A., Merville, M.-P., & Bours, V. (February 2004). Regulation of HER-2 oncogene expression by cyclooxygenase-2 and prostaglandin E2. Oncogene, 23 (8), 1631-1635. doi:10.1038/sj.onc.1207295 Peer Reviewed verified by ORBi |
 | Benoit, V., Chariot, A., Delacroix, L., Deregowski, V., Jacobs, N., Merville, M.-P., & Bours, V. (2004). Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappa B through c-FLIP-L expression. Cancer Research, 64 (8), 2684-2691. doi:10.1158/0008-5472.CAN-03-2914 Peer Reviewed verified by ORBi |
 | Viatour, P., Legrand-Poels, S., van Lint, C., Warnier, M., Merville, M.-P., Gielen, J.-L., Piette, J., Bours, V., & Chariot, A. (21 November 2003). Cytoplasmic I kappa B alpha increases NF-kappa B-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3. Journal of Biological Chemistry, 278 (47), 46541-46548. doi:10.1074/jbc.M306381200 Peer Reviewed verified by ORBi |
 | Mauro, C., Vito, P., Mellone, S., Pacifico, F., Chariot, A., Formisano, S., & Leonardi, A. (12 September 2003). Role of the adaptor protein CIKS in the activation of the IKK complex. Biochemical and Biophysical Research Communications, 309 (1), 84-90. doi:10.1016/S0006-291X(03)01532-8 Peer reviewed |
 | Adam, E., Quivy, V., Bex, F., Chariot, A., Collette, Y., Vanhulle, C., Haterte, S., Goffin, V., Nguyen, T. L.-A., Gloire, G., Carrard, G., Friguet, B., de Launoit, Y., Burny, A., Bours, V., Piette, J., & Van Lint, C. (September 2003). Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. Molecular and Cellular Biology, 23 (17), 6200-6209. doi:10.1128/MCB.23.17.6200-6209.2003 Peer Reviewed verified by ORBi |
 | Viatour, P., Bentires-Alj, M., Chariot, A., Deregowski, V., de Leval, L., Merville, M.-P., & Bours, V. (July 2003). NF-kappa B2/p100 induces Bcl-2 expression. Leukemia, 17 (7), 1349-1356. doi:10.1038/sj.leu.2402982 Peer Reviewed verified by ORBi |
| Chariot, A., Meuwis, M.-A., Bonif, M., Leonardi, A., Merville, M.-P., Gielen, J.-L., Piette, J., Siebenlist, U., & Bours, V. (April 2003). NF-kappa B activating scaffold proteins as signaling molecules and putative therapeutic targets. Current Medicinal Chemistry, 10 (7), 593-602. doi:10.2174/0929867033457926 Peer Reviewed verified by ORBi |
 | Bentires-Alj, M., Barbu, V., Fillet, M., Chariot, A., Relic, B., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (2003). NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 22, 90-97. doi:10.1038/sj.onc.1206056 Peer Reviewed verified by ORBi |
 | Viatour, P., Legrand-Poels, S., Van Lint, C., Warnier, M., Merville, M.-P., Gielen, J., Piette, J., BOURS, V., & Chariot, A. (2003). Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histones deacetylases (HDAC1 and HDAC3). Journal of Biological Chemistry. Peer Reviewed verified by ORBi |
 | Quivy, V., Adam, E., Collette, Y., Demonte, D., Chariot, A., Vanhulle, C., Berkhout, B., Castellano, R., de Launoit, Y., Burny, A., Piette, J., Bours, V., & Van Lint, C. (November 2002). Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappa B and inhibitors of deacetylases: Potential perspectives for the development of therapeutic strategies. Journal of Virology, 76 (21), 11091-11103. doi:10.1128/JVI.76.21.11091-11103.2002 Peer Reviewed verified by ORBi |
 | Chariot, A., Leonardi, A., Muller, J.-N., Bonif, M., Brown, K., & Siebenlist, U. (04 October 2002). Association of the adaptor TANK with the IκB kinase (IKK) regulator NEMO connects IKK complexes with IKKε and TBK1 kinases. Journal of Biological Chemistry, 277 (40), 37029-37036. doi:10.1074/jbc.M205069200 Peer Reviewed verified by ORBi |
 | Leonardi, A., Chariot, A., Claudio, E., Cunningham, K., & Siebenlist, U. (12 September 2000). CIKS, a connection to Ikappa B kinase and stress-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America, 97 (19), 10494-10499. doi:10.1073/pnas.190245697 Peer Reviewed verified by ORBi |
 | Chariot, A., Gielen, J., Merville, M.-P., & Bours, V. (December 1999). The homeodomain-containing proteins: an update on their interacting partners. Biochemical Pharmacology, 58, 1851-1857. doi:10.1016/S0006-2952(99)00234-8 Peer Reviewed verified by ORBi |
 | Chariot, A., Princen, F., Gielen, J., Merville, M.-P., Franzoso, G., Brown, K., Siebenlist, U., & Bours, V. (10 February 1999). Ikappab-Alpha Enhances Transactivation by the Hoxb7 Homeodomain-Containing Protein. Journal of Biological Chemistry, 274 (9), 5318-25. doi:10.1074/jbc.274.9.5318 Peer Reviewed verified by ORBi |
 | Chariot, A., Van Lint, C., Chapelier, M., Gielen, J., Merville, M.-P., & Bours, V. (1999). CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein. Oncogene, 18, 4007-4012. doi:10.1038/sj.onc.1202776 Peer Reviewed verified by ORBi |
Chariot, A., Senterre-Lesenfants, S., Sobel, M. E., & Castronovo, V. (01 October 1998). Molecular Cloning of a Mutated Hoxb7 Cdna Encoding a Truncated Transactivating Homeodomain-Containing Protein. Journal of Cellular Biochemistry, 71 (1), 46-54. doi:10.1002/(SICI)1097-4644(19981001)71:1<46::AID-JCB5>3.0.CO;2-1 Peer Reviewed verified by ORBi |
 | Chariot, A., & Gielen, J. (1998). The HOXC6 homeodomain-containing proteins. International Journal of Biochemistry and Cell Biology, 30, 651-655. doi:10.1016/S1357-2725(97)00136-2 Peer Reviewed verified by ORBi |
 | Chariot, A., & Castronovo, V. (11 May 1996). Detection of Hoxa1 Expression in Human Breast Cancer. Biochemical and Biophysical Research Communications, 222 (2), 292-7. doi:10.1006/bbrc.1996.0737 Peer reviewed |
 | Chariot, A., Castronovo, V., Le, P., Gillet, C., Sobel, M. E., & Gielen, J. (1996). Cloning and expression of a new HOXC6 transcript encoding a repressing protein. Biochemical Journal, 319, 91-97. doi:10.1042/bj3190091 Peer Reviewed verified by ORBi |
 | Chariot, A., Moreau, L., Senterre, G., Sobel, M. E., & Castronovo, V. (13 October 1995). Retinoic Acid Induces Three Newly Cloned Hoxa1 Transcripts in Mcf7 Breast Cancer Cells. Biochemical and Biophysical Research Communications, 215 (2), 713-20. doi:10.1006/bbrc.1995.2522 Peer reviewed |
 | Charlier, C., Chariot, A., Antoine, N., Merville, M.-P., Gielen, J., & Castronovo, V. (January 1995). Tamoxifen and its active metabolite inhibit growth of estrogen receptor-negative MDA-MB-435 cells. Biochemical Pharmacology, 49, 351-358. doi:10.1016/0006-2952(94)00492-5 Peer Reviewed verified by ORBi |
Castronovo, V., Kusaka, M., Chariot, A., Gielen, J.-L., & Sobel, M. (13 January 1994). Homeobox Genes: Potential Candidates for the Transcriptional Control of the Transformed and Invasive Phenotype. Biochemical Pharmacology, 47 (1), 137-43. doi:10.1016/0006-2952(94)90447-2 Peer Reviewed verified by ORBi |