Profil

Marichal Thomas

Physiologie générale et des systèmes

Département des sciences fonctionnelles (DSF) > GIGA

See author's contact details
ORCID
0000-0003-1688-6291
Main Referenced Co-authors
Bureau, Fabrice  (75)
Desmet, Christophe  (49)
Lekeux, Pierre  (32)
Sabatel, Catherine  (30)
Radermecker, Coraline  (27)
Main Referenced Keywords
Lung (16); Animals (12); Mice (10); Humans (9); Macrophages (8);
Main Referenced Unit & Research Centers
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège [BE] (4)
FARAH. Médecine vétérinaire comparée - ULiège [BE] (2)
Cellular and Molecular Physiology, GIGA-R, University of Liege, Belgium (1)
Main Referenced Disciplines
Life sciences: Multidisciplinary, general & others (68)
Biochemistry, biophysics & molecular biology (49)
Veterinary medicine & animal health (32)
Immunology & infectious disease (25)
Cardiovascular & respiratory systems (6)

Publications (total 154)

The most downloaded
681 downloads
Radermecker, C., Louis, R., Bureau, F., & Marichal, T. (2018). Role of neutrophils in allergic asthma. Current Opinion in Immunology, 54, 28-34. doi:10.1016/j.coi.2018.05.006 https://hdl.handle.net/2268/241113

The most cited

567 citations (Scopus®)

Chakarov, S., Lim, H. Y., Tan, L., Lim, S. Y., See, P., Lum, J., Zhang, X.-M., Foo, S., Nakamizo, S., Duan, K., Kong, W. T., Gentek, R., Balachander, A., Carbajo, D., Bleriot, C., Malleret, B., Tam, J. K. C., Baig, S., Shabeer, M., ... Ginhoux, F. (2019). Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science, 363 (6432). doi:10.1126/science.aau0964 https://hdl.handle.net/2268/234271

The most significant

Vanneste, D., Bai, Q., Hasan, S., Peng, W., Pirottin, D., Schyns, J., Maréchal, P., Ruscitti, C., Meunier, M., Liu, Z., Legrand, C., Fievez, L., Ginhoux, F., Radermecker, C., Bureau, F., & Marichal, T. (March 2023). MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nature Immunology, 24 (5), 827 - 840. doi:10.1038/s41590-023-01468-3
Peer Reviewed verified by ORBi

Radermecker, C.* , Sabatel, C.* , Vanwinge, C., Ruscitti, C., Marechal, P., Perin, F., Schyns, J., Rocks, N., Toussaint, M., Cataldo, D., Johnston, S. L., Bureau, F.* , & Marichal, T.*. (2019). Locally instructed CXCR4(hi) neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps. Nature Immunology. doi:10.1038/s41590-019-0496-9
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Sabatel, C.* , Radermecker, C.* , Fievez, L.* , Paulissen, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., Quatresooz, P., Sirard, J.-C., Cataldo, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T.* , & Bureau, F.*. (2017). Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages. Immunity, 46 (3), 457-473. doi:10.1016/j.immuni.2017.02.016
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marichal, T., Starkl, P., Reber, L. L., Kalesnikoff, J., Oettgen, H. C., Tsai, M., Metz, M., & Galli, S. J. (2013). A Beneficial Role for Immunoglobulin E in Host Defense against Honeybee Venom. Immunity, 39 (5), 963-75. doi:10.1016/j.immuni.2013.10.005
Peer Reviewed verified by ORBi

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K. J., Bureau, F.* , & Desmet, C.*. (August 2011). DNA released from dying host cells mediates aluminum adjuvant activity. Nature Medicine, 17, 996-1002. doi:10.1038/nm.2403
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.


Ruscitti, C.* , Radermecker, C.* , & Marichal, T.*. (01 April 2024). Journey of monocytes and macrophages upon influenza A virus infection. Current Opinion in Virology, 66, 101409. doi:10.1016/j.coviro.2024.101409
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Legrand, C., Vanneste, D., Hego, A., Sabatel, C., Mollers, K., Schyns, J., Maréchal, P., Abinet, J., Tytgat, A., Liégeois, M., Polese, B., Meunier, M., Radermecker, C., Fievez, L., Bureau, F., & Marichal, T. (2024). Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3+ Regulatory T Cells. American Journal of Respiratory Cell and Molecular Biology. doi:10.1165/rcmb.2023-0254OC
Peer Reviewed verified by ORBi

Blanquer, A., Rivas, F., Gérardy, M., Sarlet, M., Moula, N., Ziegler, U., Groschup, M. H., Desmecht, D., Marichal, T., & Garigliany, M.-M. (03 January 2024). Evaluation of Non-Vector Transmission of Usutu Virus in Domestic Canaries (Serinus canaria). Viruses, 16 (1), 79. doi:10.3390/v16010079
Peer Reviewed verified by ORBi

Rizzoli, E., Fastrès, A., Fievez, L., Marichal, T., & Clercx, C. (2023). Generation of a comprehensive molecular cell atlas of the healthy canine lung. Journal of Veterinary Internal Medicine. doi:10.1111/jvim.16930
Peer Reviewed verified by ORBi

Loos, P., Marichal, T., Machiels, B., & Gillet, L. (20 September 2023). Differentiation of Bone Marrow Monocytes into Alveolar Macrophages-like Cells through Co-culture with Lung Epithelial Cells and Group 2 Innate Lymphoid Cells. Bio-protocol, 13 (18), 4818. doi:10.21769/BioProtoc.4818
Peer Reviewed verified by ORBi

Dewals, B. G., Yang, B., Sanchez, G. S., Lavergne, A., Piedfort, O., Peng, G., Aguirre, A. M., Petrellis, G., Katsandegwaza, B., Isterdael, G. V., Duyse, J. V., Bai, Q., Marichal, T., Machiels, B., Nitschke, L., Najafabadi, H., King, I., & Vermijlen, D. (2023). IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells. Research Square. doi:10.21203/rs.3.rs-2747693/v1

Vanneste, D., Bai, Q., Hasan, S., Peng, W., Pirottin, D., Schyns, J., Maréchal, P., Ruscitti, C., Meunier, M., Liu, Z., Legrand, C., Fievez, L., Ginhoux, F., Radermecker, C., Bureau, F., & Marichal, T. (March 2023). MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nature Immunology, 24 (5), 827 - 840. doi:10.1038/s41590-023-01468-3
Peer Reviewed verified by ORBi

Loos, P., Baiwir, J., Maquet, C., Javaux, J., Sandor, R., LALLEMAND, F., Marichal, T., Machiels, B.* , & Gillet, L.*. (24 February 2023). Dampening type 2 properties of group 2 innate lymphoid cells by a gammaherpesvirus infection reprograms alveolar macrophages. Science Immunology, 8 (80), 9041. doi:10.1126/sciimmunol.abl9041
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

August, A., & Marichal, T. (February 2023). Eosinophils and Lung Mucosal Antibody Production: Is Location the Key? American Journal of Respiratory Cell and Molecular Biology, 68 (2), 124 - 126. doi:10.1165/rcmb.2022-0410ED
Editorial reviewed

Rizzoli, E., Fastrès, A., Roels, E., Garigliany, M.-M., Marichal, T., Puré, E., & Clercx, C. (15 December 2022). Expression of fibroblast activation protein in dogs with idiopathic pulmonary fibrosis or lung cancer [Poster presentation]. 9th FARAH Day, Liège, Belgium.
Editorial reviewed

Rizzoli, E., Fastrès, A., Roels, E., Garigliany, M.-M., Marichal, T., Puré, E., & Clercx, C. (03 November 2022). Expression of Fibroblast Activation Protein in lungs of dogs with idiopathic pulmonary fibrosis and dogs with lung cancer. Journal of Veterinary Internal Medicine, 36, 2455–2551.
Peer Reviewed verified by ORBi

Rizzoli, E., Fastrès, A., Roels, E., Garigliany, M.-M., Marichal, T., Puré, E., & Clercx, C. (02 October 2022). Expression of fibroblast activation protein in canine idiopathic pulmonary fibrosis [Poster presentation]. 21st International Colloquium on Lung and Airway Fibrosis (ICLAF), Reykjavik, Iceland.

Pierre, N., Huynh-Thu, V. A., Marichal, T., Allez, M., Bouhnik, Y., Laharie, D., Bourreille, A., Colombel, J.-F., Meuwis, M.-A., Louis, E., & GETAID (Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif). (2022). Distinct blood protein profiles associated with the risk of short-term and mid/long-term clinical relapse in patients with Crohn's disease stopping infliximab: when the remission state hides different types of residual disease activity. Gut, 2022-327321. doi:10.1136/gutjnl-2022-327321
Peer Reviewed verified by ORBi

Janssen, P.* , Tosi, I.* , Hego, A., Maréchal, P., Marichal, T.* , & Radermecker, C.*. (13 July 2022). Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity. Frontiers in Immunology, 13. doi:10.3389/fimmu.2022.921077
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Stakenborg, M., Abdurahiman, S., De Simone, V., Goverse, G., Stakenborg, N., van Baarle, L., Wu, Q., Pirottin, D., Kim, J.-S., Chappell-Maor, L., Pintelon, I., Thys, S., Pollenus, E., Boon, L., Van den Steen, P., Hao, M., Van Ginderachter, J. A., Boeckxstaens, G. E., Timmermans, J.-P., ... Matteoli, G. (June 2022). Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation. Mucosal Immunology, 15 (6), 1296 - 1308. doi:10.1038/s41385-022-00563-2
Peer Reviewed verified by ORBi

Radermecker, C., Hego, A., Vanwinge, C., & Marichal, T. (2022). Methods to Detect Neutrophil Extracellular Traps in Asthma. In Methods in Molecular Biology. Springer Nature. doi:10.1007/978-1-0716-2364-0_20
Peer Reviewed verified by ORBi

Liégeois, M., Bai, Q., Fievez, L., Pirottin, D., Legrand, C., Guiot, J., Schleich, F., Corhay, J.-L., Louis, R., Marichal, T., & Bureau, F. (2022). Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking. American Journal of Respiratory Cell and Molecular Biology, 67 (2), 241 - 252. doi:10.1165/rcmb.2021-0563OC
Peer Reviewed verified by ORBi

Fastrès, A., Roels, E., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (2022). Osteopontin-expressing macrophages in dogs affected with canine idiopathic pulmonary fibrosis, a model for human idiopathic pulmonary fibrosis [Poster presentation]. 21st International Colloquium on Lung and Airway Fibrosis (ICLAF).

Marichal, T. (2021). Lung neutrophils: critical regulators of immune-mediated disorders and homeostasis [Paper presentation]. J2R Journées de Recherche Respiratoire 2021, Brest, France.

Stackowicz, J., Gaudenzio, N., Serhan, N., Conde, E., Godon, O., Marichal, T., Starkl, P., Balbino, B., Roers, A., Bruhns, P., Jönsson, F., Moguelet, P., Georgin-Lavialle, S., Broderick, L., Hoffman, H. M., Galli, S. J., & Reber, L. L. (2021). Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome. The Journal of experimental medicine, 218 (10). doi:10.1084/jem.20201466
Peer reviewed

Marichal, T. (2021). Lung neutrophils: regulators of immune-mediated disorders [Paper presentation]. Nature Café on Type 2 Immunity.

Marichal, T. (2021). Lung neutrophils: critical regulators of immune-mediated disorders and homeostasis [Paper presentation]. Annual congress of the Swiss Society for Allergy and Immunology 2021.

Starkl, P., Gaudenzio, N., Marichal, T., Reber, L. L., Sibilano, R., Watzenboeck, M. L., Fontaine, F., Mueller, A. C., Tsai, M., Knapp, S., & Galli, S. J. (2021). IgE antibodies increase honeybee venom responsiveness and detoxification efficiency of mast cells. Allergy. doi:10.1111/all.14852
Peer Reviewed verified by ORBi

Marichal, T. (2021). Lung neutrophils: critical regulators of immune-mediated disorders and homeostasis [Paper presentation]. Allergy Research Today Annual Meeting.

Radermecker, C., Hego, A., Delvenne, P., & Marichal, T. (2021). Identification and Quantitation of Neutrophil Extracellular Traps in Human Tissue Sections. Bio-protocol, 11 (18), 4159. doi:10.21769/BioProtoc.4159
Peer Reviewed verified by ORBi

Fastrès, A., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (15 December 2020). Identification of pro-fibrotic macrophage populations by single-cell transcriptomic analysis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis. Frontiers in Immunology, 11, 611749. doi:10.3389/fimmu.2020.611749
Peer Reviewed verified by ORBi

Fastrès, A., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (20 November 2020). Identification of pro-fibrotic macrophages populations by single-cell transcriptomic analysis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis [Paper presentation]. 7th FARAH DAY, Liège, Belgium.

Radermecker, C., Detrembleur, N., Guiot, J., Cavalier, E., HENKET, M., D'Emal, C., Vanwinge, C., Cataldo, D., Oury, C., Delvenne, P., & Marichal, T. (November 2020). Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19. Journal of Experimental Medicine, 217 (12). doi:10.1084/jem.20201012
Peer Reviewed verified by ORBi

Fastrès, A., Pirottin, D., Fievez, L., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (30 July 2020). Characterization of the bronchoalveolar lavage fluid by single cell gene expression analysis in healthy dogs: a promising technique. Frontiers in Immunology, 11, 1707. doi:10.3389/fimmu.2020.01707
Peer Reviewed verified by ORBi

Starkl, P., Watzenboeck, M. L., Popov, L. M., Zahalka, S., Hladik, A., Lakovits, K., Radhouani, M., Haschemi, A., Marichal, T., Reber, L. L., Gaudenzio, N., Sibilano, R., Stulik, L., Fontaine, F., Mueller, A. C., Amieva, M. R., Galli, S. J., & Knapp, S. (2020). IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity, 53 (4), 793-804.e9. doi:10.1016/j.immuni.2020.08.002
Peer Reviewed verified by ORBi

Galli, S. J., Metz, M., Starkl, P., Marichal, T., & Tsai, M. (2020). Mast cells and IgE in defense against lethality of venoms: Possible "benefit" of allergy[]. Allergo journal international, 29 (2), 46-62. doi:10.1007/s40629-020-00118-6
Peer reviewed

Marichal, T. (2020). Endothelial cells instruct macrophages on how to Rspond to lung injury. Nature Immunology. doi:10.1038/s41590-020-00806-z

Marichal, T., Boyman, O., & Reber, L. L. (2020). Editorial: Role of Neutrophils in Inflammatory Diseases. Frontiers in Immunology, 11, 627939. doi:10.3389/fimmu.2020.627939

Fastrès, A., Pirottin, D., Fievez, L., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (2020). Characterization of the bronchoalveolar lavage fluid by single cell gene expression analysis in healthy dogs: a promising technique. Journal of Veterinary Internal Medicine, 34 (6). doi:10.1111/jvim.15924

Marichal, T. (2020). Lung NETs in severe Covid-19: does location matter? [Paper presentation]. Neutrophils in Covid-19 Banbury Center of Cold Spring Harbor.

Marichal, T. (2020). Lung neutrophils: regulators of immune-mediated diseases [Paper presentation]. BERS Annual Congress.

Marichal, T. (December 2019). Immunology of asthma : when myeloid cells appear on stage [Paper presentation]. Inserm, Toulouse, France.

Marichal, T. (04 October 2019). Immunology of asthma : when myeloid cells appear on stage [Paper presentation]. Institut Pasteur, Lille, France.

Rocks, N., Vanwinge, C., Radermecker, C., Blacher, S., Gilles, C., Marée, R., Gillard, A., Evrard, B., Pequeux, C., Marichal, T., Noël, A., & Cataldo, D. (08 September 2019). Ozone-primed neutrophils promote early steps of tumor cell metastasis to lungs by enhancing their NET production [Poster presentation]. IASLC 2019 World Conference on Lung Cancer.

Marichal, T. (13 June 2019). Immunology of asthma : when myeloid cells appear on stage [Paper presentation]. Maastricht University, Maastricht, Netherlands.

Rocks, N., Vanwinge, C., Radermecker, C., Blacher, S., Gilles, C., Marée, R., Gillard, A., Evrard, B., Pequeux, C., Marichal, T., Noël, A., & Cataldo, D. (29 May 2019). Ozone-primed neutrophils promote early steps of tumor cell metastasis to lungs by enhancing their NET production. Thorax, 0, 1-12. doi:10.1136/thoraxjnl-2018-211990
Peer Reviewed verified by ORBi

Marichal, T. (20 May 2019). Locally instructed neutrophils mediate environment-driven allergic asthma onset [Paper presentation]. Université d'Orléans, Orleans, France.

Marichal, T. (03 April 2019). Immunology of asthma : when myeloid cells appear on stage [Paper presentation]. Université Paris-Diderot, Paris, France.

Marichal, T. (09 March 2019). Host DNA released by NETS mediate rhinovirus-induced type 2 allergic asthma exacerbations [Paper presentation]. European Respiratory Society (ERS) Lung Science Conference, Estoril, Portugal.

Lee, M. S. J., Natsume-Kitatani, Y., Temizoz, B., Fujita, Y., Konishi, A., Matsuda, K., Igari, Y., Tsukui, T., Kobiyama, K., Kuroda, E., Onishi, M., Marichal, T., Ise, W., Inoue, T., Kurosaki, T., Mizuguchi, K., Akira, S., Ishii, K. J., & Coban, C. (2019). B cell-intrinsic MyD88 signaling controls IFN-γ-mediated early IgG2c class switching in mice in response to a particulate adjuvant. European Journal of Immunology, 49 (9), 1433-1440. doi:10.1002/eji.201848084
Peer Reviewed verified by ORBi

Radermecker, C.* , Sabatel, C.* , Vanwinge, C., Ruscitti, C., Marechal, P., Perin, F., Schyns, J., Rocks, N., Toussaint, M., Cataldo, D., Johnston, S. L., Bureau, F.* , & Marichal, T.*. (2019). Locally instructed CXCR4(hi) neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps. Nature Immunology. doi:10.1038/s41590-019-0496-9
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Schyns, J., Bai, Q., Ruscitti, C., Radermecker, C., De Schepper, S., Chakarov, S., Farnir, F., Pirottin, D., Ginhoux, F., Boeckxstaens, G., Bureau, F., & Marichal, T. (2019). Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung. Nature Communications, 10 (1), 3964. doi:10.1038/s41467-019-11843-0
Peer Reviewed verified by ORBi

Serhan, N., Basso, L., Sibilano, R., Petitfils, C., Meixiong, J., Bonnart, C., Reber, L. L., Marichal, T., Starkl, P., Cenac, N., Dong, X., Tsai, M., Galli, S. J., & Gaudenzio, N. (2019). House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation. Nature Immunology. doi:10.1038/s41590-019-0493-z
Peer Reviewed verified by ORBi

Chakarov, S., Lim, H. Y., Tan, L., Lim, S. Y., See, P., Lum, J., Zhang, X.-M., Foo, S., Nakamizo, S., Duan, K., Kong, W. T., Gentek, R., Balachander, A., Carbajo, D., Bleriot, C., Malleret, B., Tam, J. K. C., Baig, S., Shabeer, M., ... Ginhoux, F. (2019). Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science, 363 (6432). doi:10.1126/science.aau0964
Peer Reviewed verified by ORBi

El Abbas, S., Radermecker, C., Bai, Q., BEGUIN, C., Schyns, J., Meunier, M., Pirottin, D., Desmet, C., Meuwis, M.-A., Art, T., Louis, E., Tam, S.-Y., Tsai, M., Bureau, F., Galli, S. J., & Marichal, T. (2019). Epithelial RABGEF1 deficiency promotes intestinal inflammation by dysregulating intrinsic MYD88-dependent innate signaling. Mucosal Immunology. doi:10.1038/s41385-019-0211-z
Peer Reviewed verified by ORBi

Marichal, T. (25 October 2018). Towards a better understanding of lung interstitial macrophage diversity [Paper presentation]. Mini-Symposium on Tissue Macrophages, Louvain, Belgium.

Marichal, T. (2018). Neutrophils in allergic asthma. In Proceedings of the ECI.
Peer reviewed

Radermecker, C., Sabatel, C., Vanwinge, C., Rocks, N., Toussaint, M., CATALDO, D., Johnston, S., Bureau, F., & Marichal, T. (September 2018). NEUTROPHIL EXTRACELLULAR TRAPS AS MAJOR DETERMINANTS OF ASTHMA [Paper presentation]. European Congress of Immunology.

Radermecker, C., Sabatel, C., Vanwinge, C., Rocks, N., Schyns, J., Ruscitti, C., Maréchal, P., Toussaint, M., CATALDO, D., Johnston, S., Bureau, F., & Marichal, T. (June 2018). NEUTROPHIL EXTRACELLULAR TRAPS AS MAJOR DETERMINANTS OF ASTHMA [Paper presentation]. The Neutrophil 2018.

Schyns, J., Pirottin, D., Bureau, F., & Marichal, T. (28 May 2018). Towards a better understanding of lung interstitial macrophages identity [Poster presentation]. EDT-Immunology Day 2018, Liège, Belgium.

Schyns, J., Bureau, F., & Marichal, T. (11 March 2018). Lung Interstitial Macrophages: Past, Present, and Future. Journal of Immunology Research, 2018. doi:10.1155/2018/5160794
Peer Reviewed verified by ORBi

Marichal, T. (2018). Lung-resident eosinophils contribute to lung immunophysiology [Paper presentation]. AstraZeneca Workshop in pneumology, Liège, Belgium.

Gaudenzio, N., Marichal, T., Galli, S. J., & Reber, L. L. (2018). Genetic and Imaging Approaches Reveal Pro-Inflammatory and Immunoregulatory Roles of Mast Cells in Contact Hypersensitivity. Frontiers in Immunology, 9, 1275. doi:10.3389/fimmu.2018.01275
Peer Reviewed verified by ORBi

Balbino, B., Conde, E., Marichal, T., Starkl, P., & Reber, L. L. (2018). Approaches to target IgE antibodies in allergic diseases. Pharmacology and Therapeutics. doi:10.1016/j.pharmthera.2018.05.015
Peer Reviewed verified by ORBi

Radermecker, C., Louis, R., Bureau, F., & Marichal, T. (2018). Role of neutrophils in allergic asthma. Current Opinion in Immunology, 54, 28-34. doi:10.1016/j.coi.2018.05.006
Peer Reviewed verified by ORBi

Liégeois, M.* , Legrand, C.* , Desmet, C.* , Marichal, T.* , & Bureau, F.*. (2018). The interstitial macrophage: A long-neglected piece in the puzzle of lung immunity. Cellular Immunology, 330, 91-96. doi:10.1016/j.cellimm.2018.02.001
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marichal, T. (15 December 2017). Neutrophil extracellular traps are major determinants of airway allergy [Paper presentation]. Type 2 Immunity Meeting in Bern, Bern, Switzerland.

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

El Abbas, S., Beguin, C., Schyns, J., Pirottin, D., Tsai, M., Tam, S., Galli, S., Bureau, F., & Marichal, T. (2017). Characterization and regulation of the intestinal epithelial cell response to colitogenic triggers. In Proceedings of Annual meeting of the French Society for Immunology (SFI).

El Abbas, S., BEGUIN, C., Schyns, J., Pirottin, D., Tsai, M., Tam, S., Galli, S., Bureau, F., & Marichal, T. (2017). Rab guanine nucleotide exchange factor 1 (Rabgef1) restricts intestinal inflammation by limiting pro-inflammatory signals in Intestinal Epithelial Cells (IECs). In Proceedings: 4th FARAH-DAY. Liège, Belgium: Presses de la Faculté de Médecine vétérinaire.

Marichal, T. (October 2017). Towards a better understanding of lung interstitial macrophage diversity [Paper presentation]. Macrophage Biology in the Single-Cell Era, Gand, Belgium.

Radermecker, C., Sabatel, C., Toussaint, M., Johnston, S., Bureau, F., & Marichal, T. (20 June 2017). Release of Neutrophils Extracellular Traps as a main trigger for asthma onset [Poster presentation]. European Academy of Allergy and Clinical Immunology, Finland.

Marichal, T. (April 2017). Innate danger signals influencing allergic asthma development : focus on bacterial and host DNA [Paper presentation]. 10th Bridging the Gap Symposium, Vienne, Austria.

Bureau, F., Marichal, T., Desmet, C., Sabatel, C., Radermecker, C., Fievez, L., & olivier, S. (09 March 2017). Procédés de différenciation in vitro de monocytes en macrophages régulateurs.

Sabatel, C., Radermecker, C., Fievez, L., PAULISSEN, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., QUATRESOOZ, P., Sirard, J.-C., CATALDO, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (01 February 2017). Bacterial CpG-DNA prevents asthma by expanding lung interstitial regulatory macrophages from local and splenic reservoir monocytes [Paper presentation]. GIGA DAY 2017, Liège, Belgium.

Radermecker, C., Sabatel, C., Toussaint, M., Johnston, S., Bureau, F., & Marichal, T. (24 January 2017). Release of Neutrophils Extracellular Traps as a main trigger for asthma onset [Paper presentation]. 6th NIF Winter School on Advanced Immunology, Singapore, Singapore.

Sabatel, C.* , Radermecker, C.* , Fievez, L.* , Paulissen, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., Quatresooz, P., Sirard, J.-C., Cataldo, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T.* , & Bureau, F.*. (2017). Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages. Immunity, 46 (3), 457-473. doi:10.1016/j.immuni.2017.02.016
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marichal, T., Mesnil, C., & Bureau, F. (2017). Homeostatic Eosinophils: Characteristics and Functions. Frontiers in Medicine, 4, 101. doi:10.3389/fmed.2017.00101
Peer Reviewed verified by ORBi

Toussaint, M., Jackson, D. J., Swieboda, D., Guedan, A., Tsourouktsoglou, T.-D., Ching, Y. M., Radermecker, C., Makrinioti, H., Aniscenko, J., Edwards, M. R., Solari, R., Farnir, F., Papayannopoulos, V., Bureau, F.* , Marichal, T.* , & Johnston, S. L.*. (2017). Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation. Nature Medicine, 23, 681-691. doi:10.1038/nm.4332
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Reber, L. L., Gillis, C. M., Starkl, P., Jonsson, F., Sibilano, R., Marichal, T., Gaudenzio, N., Berard, M., Rogalla, S., Contag, C. H., Bruhns, P., & Galli, S. J. (2017). Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide. Journal of Experimental Medicine, 214 (5), 1249-1258. doi:10.1084/jem.20161238
Peer Reviewed verified by ORBi

Galli, S. J., Starkl, P., Marichal, T., & Tsai, M. (2017). Mast Cells and IgE can Enhance Survival During Innate and Acquired Host Responses to Venoms. Transactions of the American Clinical and Climatological Association, 128, 193-221.
Peer Reviewed verified by ORBi

Radermecker, C., Sabatel, C., Vanwinge, C., Rocks, N., Cataldo, D., Bureau, F., & Marichal, T. (2017). Release of Neutrophils Extracellular Traps as a main trigger for asthma onset [Paper presentation]. Société Française d'immunologie.

Marichal, T. (28 November 2016). Epithelial RabGEF1 regulates skin homeostasis [Paper presentation]. Congrès annuel de la Société Française d'Immunologie (SFI) 2016, Paris, France.

El Abbas, S., Beguin, C., Mesnil, C., Schyns, J., Tsai, M., Tam, S., Galli, S., Pirottin, D., Bureau, F., & Marichal, T. (2016). Epithelial Rab guanine nucleotide exchange factor 1 (Rabgef1) deficiency increases susceptibility to DSS-induced intestinal inflammation in mice. In Proceedings: 3rd FARAH-DAY.

Mesnil, C., Raulier, S., Paulissen, G., Xiao, X., Birrell, M., Pirottin, D., Janss, T., Starkl, P., Ramery, E., HENKET, M., SCHLEICH, F., Radermecker, M., Thielemans, K., Gillet, L., Thiry, M., Belvisi, M., LOUIS, R., Desmet, C., Marichal, T., & Bureau, F. (21 October 2016). Lung resident eosinophils represent a distinct cell subset with homeostatic functions [Paper presentation]. FARAH Day 2016, Liege, Belgium.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Chakarov, S., Toussaint, M., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (2016). CpG-DNA expand immunosuppressive interstitial macrophages from Ly6c+ local precursors. In Proceeding of Cell Symposia: 100 years of phagocytes.
Peer reviewed

El Abbas, S., Beguin, C., Mesnil, C., Schyns, J., Tsai, M., Tam, S., Galli, S., Bureau, F., & Marichal, T. (27 May 2016). Epithelial Rab guanine nucleotide exchange factor 1 (Rabgef1) deficiency increases susceptibility to DSS-induced intestinal inflammation in mice [Poster presentation]. EDT Immunology 1st meeting, Gosselies, Gosselies, Belgium.

Schyns, J., Legrand, C., Bureau, F., & Marichal, T. (27 May 2016). Exploring the role of CD169+ lymph node macrophages in alum adjuvant activity [Poster presentation]. FNRS-Immunology Doctoral School 2016 Immunology Day, Gosselies, Belgium.

Marichal, T. (22 April 2016). Keratinocyte RabGEF1 maintains skin homeostasis in vivo [Paper presentation]. Spring Meeting de la Société belge de physiologie et pharmacologie.

Marichal, T. (21 April 2016). Novel trigger and function of type 2 immunity:Damage-associated host DNA and host defense against venoms [Paper presentation]. LIH INfection & Immunity Lecture series.

Marichal, T., Gaudenzio, N., El Abbas, S., Sibilano, R., Zurek, O., Starkl, P., Reber, L. L., Pirottin, D., Kim, J., Chambon, P., Roers, A., Antoine, N., Kawakami, Y., Kawakami, T., Bureau, F., Tam, S.-Y., Tsai, M., & Galli, S. J. (2016). Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. Journal of Clinical Investigation, 126 (12), 4497-4515. doi:10.1172/JCI86359
Peer Reviewed verified by ORBi

Mesnil, C.* , Raulier, S.* , Paulissen, G., Xiao, X., Birrell, M., Pirottin, D., Janss, T., Starkl, P., Ramery, E., HENKET, M., SCHLEICH, F., Radermecker, C., Thielemans, K., Gillet, L., Thiry, M., Belvisi, M., Louis, R., Desmet, C., Marichal, T.* , & Bureau, F.*. (2016). Lung-resident eosinophils represent a distinct regulatory eosinophil subset. Journal of Clinical Investigation, 126 (9), 3275-3295. doi:10.1172/JCI85664
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Mukai, K., Tsai, M., Starkl, P., Marichal, T., & Galli, S. J. (2016). IgE and mast cells in host defense against parasites and venoms. Seminars in Immunopathology. doi:10.1007/s00281-016-0565-1
Peer Reviewed verified by ORBi

Marichal, T. (2016). Role of double-stranded DNA in allergic airway inflammation [Paper presentation]. Annual Meeting of the Swiss Society for Allergology and Immunology (SSAI) 2016.

Balbino, B., Sibilano, R., Starkl, P., Marichal, T., Gaudenzio, N., Karasuyama, H., Bruhns, P., Tsai, M., Reber, L. L., & Galli, S. J. (2016). Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis. Journal of Allergy and Clinical Immunology. doi:10.1016/j.jaci.2016.05.047
Peer Reviewed verified by ORBi

Janss, T., Mesnil, C., Pirottin, D., Lemaitre, P., Marichal, T., Bureau, F.* , & Desmet, C.*. (2016). Interferon response factor-3 promotes the pro-Th2 activity of mouse lung CD11b+ conventional dendritic cells in response to house dust mite allergens. European Journal of Immunology, 46 (11), 2614-2628. doi:10.1002/eji.201646513
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Janss, T., Mesnil, C., Pirottin, D., Lemaitre, P., Marichal, T., Bureau, F.* , & Desmet, C.*. (2016). Interferon response factor-3 promotes the pro-Th2 activity of mouse myeloid CD11b+ dendritic cells. European Journal of Immunology, 46, 2614-2628.
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Gaudenzio, N., Sibilano, R., Marichal, T., Starkl, P., Reber, L. L., Cenac, N., McNeil, B. D., Dong, X., Hernandez, J. D., Sagi-Eisenberg, R., Hammel, I., Roers, A., Valitutti, S., Tsai, M., Espinosa, E., & Galli, S. J. (2016). Different activation signals induce distinct mast cell degranulation strategies. Journal of Clinical Investigation, 126 (10), 3981-3998. doi:10.1172/JCI85538
Peer Reviewed verified by ORBi

Raulier, S., Mesnil, C., Paulissen, G., Pirottin, D., Janss, T., Desmet, C., Marichal, T., & Bureau, F. (28 September 2015). Identification of a novel lung-resident eosinophil population with immunomodulatory properties in mice [Paper presentation]. ERS 2015 international congress, Amsterdam, Netherlands.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Toussaint, M., Desmet, C., Marichal, T., Bureau, F., & Chakarov, S. (Other coll.). (08 September 2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages [Poster presentation]. 4ème European Congress of Immunology, Vienne, Austria.

Marichal, T. (2015). Novel insights into type 2 immunity : host DNA and protective IgE. In Proceedings of the ECI 2015.
Peer reviewed

Marichal, T. (07 September 2015). Immunoglobulin E enhances host resistance to venoms [Paper presentation]. European Congress of Immunology.

Marichal, T. (06 June 2015). Role of double stranded DNA in allergic inflammation [Paper presentation]. European Respiratory Society Annual Symposium.

Galli, S. J., Starkl, P., Marichal, T., & Tsai, M. (2015). Mast cells and IgE in defense against venoms: Possible "good side" of allergy? Allergology International. doi:10.1016/j.alit.2015.09.002
Peer Reviewed verified by ORBi

Starkl, P.* , Marichal, T.* , Gaudenzio, N., Reber, L. L., Sibilano, R., Tsai, M., & Galli, S. J. (2015). IgE antibodies, FcepsilonRIalpha, and IgE-mediated local anaphylaxis can limit snake venom toxicity. Journal of Allergy and Clinical Immunology. doi:10.1016/j.jaci.2015.08.005
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Chakarov, S., Desmet, C., Ginhoux, F., Toussaint, M., Marichal, T., & Bureau, F. (2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages [Poster presentation]. ERS International congress.

Tsai, M., Starkl, P., Marichal, T., & Galli, S. J. (2015). Testing the 'toxin hypothesis of allergy': mast cells, IgE, and innate and acquired immune responses to venoms. Current Opinion in Immunology, 36, 80-7. doi:10.1016/j.coi.2015.07.001
Peer Reviewed verified by ORBi

Sabatel, C., Radermecker, C., Chakarov, S., Fievez, L., PAULISSEN, G., Toussaint, M., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages. European Respiratory Journal. Supplement, 46 (59), 5098.
Peer Reviewed verified by ORBi

Galli, S. J., Tsai, M., Marichal, T., Tchougounova, E., Reber, L. L., & Pejler, G. (2015). Approaches for analyzing the roles of mast cells and their proteases in vivo. Advances in Immunology, 126, 45-127. doi:10.1016/bs.ai.2014.11.002
Peer Reviewed verified by ORBi

Starkl, P., Marichal, T., Reber, L. L., Gaudenzio, N., Kalesnikoff, J., Oettgen, H. C., Tsai, M., Metz, M., & Galli, S. J. (2014). IgE antibodies and FceRI are critical components of protective type 2 immunity against honeybee and russell's viper venom in mice. In Proceedings of the Type 2 Cell Symposium - Brugge.
Peer reviewed

Marichal, T. (17 November 2014). Recent advances in type 2 immunity: Damage-associated host DNA and Protective Immunoglobulin E [Paper presentation]. Singapore Immunology Network - A*Star, Immunology Seminar, Singapore, Singapore.

Marichal, T. (13 November 2014). Recent advances in type 2 immunity: Damage-associated host DNA and Protective Immunoglobulin E [Paper presentation]. WPI-IFReC Immunology Seminar, Osaka, Japan.

Marichal, T. (October 2014). Novel role for type E Immunoglobulins: host protection against venoms [Paper presentation]. FARAH Seminar, Liege, Belgium.

Marichal, T., Starkl, P., Metz, M., & Galli, S. J. (February 2014). Une reponse allergique pour lutter contre les venins. MS. Medecine Sciences, 30 (2), 127-30. doi:10.1051/medsci/20143002004

Reber, L. L., Marichal, T., Sokolove, J., Starkl, P., Gaudenzio, N., Iwakura, Y., Karasuyama, H., Schwartz, L. B., Robinson, W. H., Tsai, M., & Galli, S. J. (2014). Contribution of mast cell-derived interleukin-1beta to uric acid crystal-induced acute arthritis in mice. Arthritis and Rheumatology, 66 (10), 2881-91. doi:10.1002/art.38747
Peer Reviewed verified by ORBi

Starkl, P., Marichal, T., Reber, L. L., Kalesnikoff, J., Oettgen, H. C., Tsai, M., Metz, M., & Galli, S. J. (2014). IgE antibodies and FceRI are critical mediators of acquired resistance against honeybee and russell's viper venom in mice. In Proceedings of the EAACI Congress 2014.
Peer reviewed

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2014). Resident CD11b+CD64-Ly6C-, but not neo-recruited inflammatory CD11b+CD64+Ly6C+ dendritic cells are able to induce allergic airway sensitization to house dust mite antigens. In proceeding of the 13th International Symposium on Dendritic Cells.
Peer reviewed

Marichal, T., Tsai, M., & Galli, S. J. (November 2013). Mast cells: potential positive and negative roles in tumor biology. Cancer Immunology Research, 1, 269-279. doi:10.1158/2326-6066.CIR-13-0119
Peer Reviewed verified by ORBi

Marichal, T. (November 2013). New concepts in type 2 immunity: Damage-associated signals and Protective IgE [Paper presentation]. Vet in Research Model, Department of Comparative medicine DVM PhDQuarterly meeting, Stanford.

Marichal, T., Reber, L., Tam, S. Y., Tsai, M., & Galli, S. (2013). Keratinocyte-restricted RabGEF-1 expression is a key regulator of skin homeostasis in vivo. In Proceedings of the 15th ICI.
Peer reviewed

Starkl, P.* , Marichal, T.* , & Galli, S. J. (2013). PLA2G3 promotes mast cell maturation and function. Nature Immunology, 14 (6), 527-9. doi:10.1038/ni.2612
* These authors have contributed equally to this work.

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2013). Resident lung CD11b+Ly6C- dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. In Proceeding of International Congress of Immunology 2013.
Peer reviewed

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2013). Resident CD11b+Ly6C-, not neo-recruited inflammatory CD11b+Ly6C+ dendritic cells mediate allergic airway sensitization to house dust mite antigens. In Proceeding of the Abcam symposium on Allergy and Asthma 2013.
Peer reviewed

Reber, L. L., Marichal, T., Mukai, K., Kita, Y., Tokuoka, S. M., Roers, A., Hartmann, K., Karasuyama, H., Nadeau, K. C., Tsai, M., & Galli, S. J. (2013). Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice. Journal of Allergy and Clinical Immunology, 132 (4), 881-8.e1-11. doi:10.1016/j.jaci.2013.06.008
Peer Reviewed verified by ORBi

Marichal, T., Starkl, P., Reber, L. L., Kalesnikoff, J., Oettgen, H. C., Tsai, M., Metz, M., & Galli, S. J. (2013). A Beneficial Role for Immunoglobulin E in Host Defense against Honeybee Venom. Immunity, 39 (5), 963-75. doi:10.1016/j.immuni.2013.10.005
Peer Reviewed verified by ORBi

Marichal, T., Starkl, P., Reber, L. L., Kalesnikoff, J., Oettgen, H. C., Tsai, M., Metz, M., & Galli, S. J. (September 2012). IgE antibodies critically contribute to acquired enhanced resistance to honeybee venom in mice [Paper presentation]. Immunology Asilomar Retreat, Pacific Grove, United States - California.

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2012). Resident non inflammatory CD11b+ lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. In Proceedings Giga Day 2012.

Marichal, T., Reber, L. L., & Galli, S. J. (2012). New models for analyzing mast cell functions in vivo. Trends in Immunology, 33 (12), 613-25. doi:10.1016/j.it.2012.09.008
Peer Reviewed verified by ORBi

Marichal, T., Bureau, F., & Desmet, C. (2012). L'ADN du soi, allie du systeme immunitaire pour la fonction adjuvante de l'alun. MS. Medecine Sciences, 28 (1), 31-3. doi:10.1051/medsci/2012281011

Mesnil, C.* , Sabatel, C.* , Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F.* , & Desmet, C.*. (2012). Resident CD11b(+)Ly6C(-) Lung Dendritic Cells Are Responsible for Allergic Airway Sensitization to House Dust Mite in Mice. PLoS ONE, 7 (12), 53242. doi:10.1371/journal.pone.0053242
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobyiama, K., Lekeux, P., Cevaiyr, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2012). Release and Innate detection of host cell DNA mediates the adjuvant effects of aluminum salts on adaptive responses. In Proceedings of the 1St Winter School Immunology.
Peer reviewed

Mesnil, C., Sabatel, C., Marichal, T., Toussaint, M., Cataldo, D., Drion, P., Lekeux, P., Bureau, F., & Desmet, C. (2012). Resident non inflammatory CD11b+ lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. In Proceeding of the J2R.
Peer reviewed

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K. J., Bureau, F.* , & Desmet, C.*. (August 2011). DNA released from dying host cells mediates aluminum adjuvant activity. Nature Medicine, 17, 996-1002. doi:10.1038/nm.2403
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marichal, T. (2011). Role de l'ADN endogène et d'Interferon Response Factor-3 dans l'induction des réponses immunitaires médiées par les lymphocytes T auxiliaires de type 2 [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/104407

Marichal, T., Bedoret Denis, Mesnil Claire, Pichavant Murielle, Goriely Stanislas, Goldman Michel, Lekeux, P., Bureau, F., & Desmet, C. (2011). Interferon Response Factor-3 is essential for house dust mite-induced airway allergy. In Proceedings of the Belgian Thoracic Society Annual Meeting.
Peer reviewed

Marichal, T., Bedoret, D., Mesnil, C., Goriely, S., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2011). IRF3 is essential for house dust mite-induced airway allergy in mice. In Proceedings GIGA-Day 2011.

Marichal, T., Bedoret, D., Mesnil, C., Pichavant, M., Goriely, S., Trottein, F., Cataldo, D., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (May 2011). Interferon Response Factor 3 is essential for house dust mite-induced airway allergy [Paper presentation]. Gaxo Smith Kline Award in Pneumology, Brussels, Belgium.

Marichal, T., Ohata, K., Bedored, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). IRF3-dependent activation of inflammatory dendritic cells by extracellular host DNA mediates the adjuvant activity of alum on TH2 responses [Paper presentation]. 25th Annual Meeting of the European Macrophage and Dendritic cell Society, Brussels, Belgium.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Release and innate immune detection of host cell DNA mediate the adjuvant activity of aluminum salts [Paper presentation]. 4th International Conference on Crossroads between Innate and Adaptive Immunity, Mykonos, Greece.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Self-DNA release mediates the adjuvant effects of aluminium salts [Poster presentation]. Cold Spring Harbor Laboratory, New-York, United States.

Legutko, A.* , Marichal, T.* , Fievez, L., Bedoret, D., Mayer, A., de Vries, H., Klotz, L., Drion, P., Heirman, C., CATALDO, D., LOUIS, R., Thielemans, K., Andris, F., Leo, O., Lekeux, P., Desmet, C.* , & Bureau, F.*. (2011). Sirtuin 1 Promotes Th2 Responses and Airway Allergy by Repressing Peroxisome Proliferator-Activated Receptor-γ Activity in Dendritic Cells. Journal of Immunology, 187 (9), 4517-4529. doi:10.4049/jimmunol.1101493
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Marichal, T., Ohata, K., Mesnil, C., Kobyiama, K., Lekeux, P., Cevaiyr, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2011). Release and innate detection of host cell DNA mediates the adjuvant effects of aluminum salts. In Proceedings of te 4th International Conference on Crossroads between Innate and Adaptive Immunity.
Peer reviewed

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). IRF3-dependent activation of inflammatory dendritic cells by extracellular host DNA mediates the adjuvant activity of alum on TH2 responses [Poster presentation]. 25th Annual Meeting of the European Macrophage and Dendritic cell Society, Brussels, Belgium.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Release and innate immune detection of host cell DNA mediate the adjuvant activity of aluminum salts [Poster presentation]. 4th International Conference on Crossroads between Innate and Adaptive Immunity, Mykonos, Greece.

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobyiama, K., Lekeux, P., Cevayir, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2011). IRF-3 dependent activation of inflammatory dendritic cells by extracellular host DNA mediates the adjuvant activity of alum on Th2 responses. In Proceedings of the 25th annual meeting of the European Macrophage and Dendritic Cell Society.
Peer reviewed

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobyiama, K., Lekeux, P., Cevayir, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (2011). Self-DNA release mediates the adjuvant effect of aluminum salts. In Proceedings of the 4th meeting on Harnessing immunity to prevent and treat diseases.
Peer reviewed

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Sabatel, C., Kobiyama, K., Lekeux, P., Coban, C., Akira, S., Ishii, K., Bureau, F., & Desmet, C. (2011). Self-DNA release mediates the adjuvant effects of aluminum salts [Poster presentation]. Cold Spring Harbor Laboratory Meeting: 4th meeting on Harnessing immunity to prevent and treat disease, New York, United States.

Marichal, T., Bedoret Denis, Mesnil, C., Goriely Stanislas, Goldman Michel, Lekeux, P., Bureau, F., & Desmet, C. (2010). Interferon Response Factor 3 is required for airway allergy to house dust mite in mice. In Short Book of the Annual Congress of the Euopean Respiratory Society (ERS), Barcelone.
Peer reviewed

Marichal, T., Ohata, K., Bedoret, D., Mesnil, C., Kobyiama, K., Lekeux, P., Cevaiyr, C., Akira, S., Ishii, K. J., Bureau, F., & Desmet, C. (February 2010). Release and innate detection of hot cell DNA mediates the adjuvant effects of aluminium salts on adaptive responses [Paper presentation]. First winter school on Advanced Immunology, Awaji Yumebutai International conference center, Japan.

Marichal, T., Bedoret, D., Mesnil, C., Pichavant, M., Goriely, S., Trottein, F., Cataldo, D., Goldman, M., Lekeux, P., Bureau, F.* , & Desmet, C.*. (2010). Interferon Response Factor 3 is essential for house dust mite-induced airway allergy. Journal of Allergy and Clinical Immunology, 126 (4), 836-844. doi:10.1016/j.jaci.2010.06.009
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Legutko, A., Marichal, T., Fievez, L., Mayer, A., Andris, F., Léo, O., Lekeux, P., & Bureau, F. (2009). Essential role of sirtuins in the pathogenesis of allergic airway inflammation. In Short book of the Annual Congress of the European Respiratory Society (ERS), Vienne.
Peer reviewed

Bedoret, D., Wallemacq, H., Marichal, T., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B. G., Thielen, C., Gustin, P., Vanderplasschen, A., Cataldo, D., Drion, P., Moser, M., Lekeux, P., & Bureau, F. (2009). Lung interstitial macrophages prevent the development of respiratory allergy. In Proceedings of The Keystone Symposia: Allergy and Asthma. Keystone, Colorado, USA.
Peer reviewed

Bedoret, D., Wallemacq, H., Marichal, T., Desmet, C., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B. G., Thielen, C., Gustin, P., de Leval, L., Van Rooijen, N., Le Moine, A., Vanderplasschen, A., Cataldo, D., Drion, P., Moser, M., Lekeux, P., & Bureau, F. (2009). Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. Journal of Clinical Investigation, 119 (12), 3723-38. doi:10.1172/JCI39717
Peer Reviewed verified by ORBi

Bedoret, D., Wallemacq, H., Marichal, T., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B. G., Thielen, C., Gustin, P., Vanderplasschen, A., Cataldo, D., Drion, P., Moser, M., Lekeux, P., & Bureau, F. (2009). A crucial role forlung interstitial macrophages in preventing airway allergy. In Short book of the Annual Congress of the European Respiratory Society (ERS), Vienne.
Peer reviewed

Bedoret, D., Wallemacq, H., Marichal, T., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B. G., Thielen, C., Gustin, P., Vanderplasschen, A., Cataldo, D., Drion, P., Moser, M., Lekeux, P., & Bureau, F. (2009). Interstitial macrophages are essential for maintaining immune homeostasis in the lung. In Proceedings of The Allergy & Asthma Symposium: Bridging Innate and Adaptive Immunity.
Peer reviewed

Marichal, T., Bedoret, D., Goriely, M., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2009). IRF3 is required for the induction of allergic airway inflammation by lung dendritic cells in a mouse model of house dust mite-induced atopic asthma. In Abstracts of the 17th Annual European Respiratory Society Congress, Vienna, Austria.
Peer reviewed

Marichal, T., Bedoret, D., Goriely, M., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2009). IRF3 is required for induction of allergic airway inflammation by dendritic cells [Paper presentation]. Abcam Allergy and Asthma Symposium, Bruges, Belgium.

Marichal, T., Bedoret, D., Goriely, S., Goldman, M., Lekeux, P., Bureau, F., & Desmet, C. (2009). IRF3 is required for induction of allergic airway inflammation by dendritic cells [Poster presentation]. Abcam Allergy and Asthma Symposium, Bruges, Belgium.

Bedoret, D., Wallemacq, H., Marichal, T., Quesada Calvo, F., Henry, E., Closset, R., Dewals, B. G., Thielen, C., Gustin, P., Vanderplasschen, A., Cataldo, D., Drion, P., Moser, M., Lekeux, P., & Bureau, F. (2008). Lung interstitial macrophages prevent lipopolysaccharide-triggered T helper type 2 responses to harmless inhaled antigens. In Proceedings of the Annual BIS-meeting.
Peer reviewed

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