[en] Our data strongly suggest that myoferlin interacts with MFN. Indeed, if myoferlin is a part of the mitochondrial fusion machinery, its silencing together with an unopposed fission would lead to mitochondrial fragmentation.
Research Center/Unit :
Giga-Cancer - ULiège d‐BRU - Dental Biomaterials Research Unit - ULiège
Disciplines :
Oncology
Author, co-author :
Anania, Sandy ; Université de Liège - ULiège > Cancer-Metastases Research Laboratory
Rademaker, Gilles ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire
Wissocq, Tom ; Université de Liège - ULiège > Cancer-Metastases Research Laboratory
Bellahcene, Akeila ; Université de Liège - ULiège > Cancer-Metastases Research Laboratory
Castronovo, Vincenzo ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire
Peulen, Olivier ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Language :
English
Title :
Role of myoferlin in mitochondrial dynamics and metabolic fitness of PDAC
Publication date :
October 2019
Number of pages :
A0
Event name :
PANCREATIC CANCER SYMPOSIUM
Event organizer :
AFRCP
Event place :
Toulouse, France
Event date :
du 23 au 24 octobre 2019
Audience :
International
Name of the research project :
Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreatic cancer
Funders :
FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture ULiège - Université de Liège Fondation Léon Fredericq
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