Profil

Rademaker Gilles

GIGA Cancer - Metastases Research Laboratory

Département des sciences biomédicales et précliniques > Biologie dans le domaine des sc. médicales et biomédicales

See author's contact details
ORCID
0000-0003-0170-781X
Main Referenced Co-authors
Peulen, Olivier  (33)
Bellahcene, Akeila  (30)
Castronovo, Vincenzo  (27)
Agirman, Ferman  (17)
Costanza, Brunella  (17)
Main Referenced Keywords
Myoferlin (25); Cancer (14); Pancreas (14); Colon (5); Metabolism (5);
Main Referenced Unit & Research Centers
d‐BRU - Dental Biomaterials Research Unit - ULiège (16)
Giga-Cancer - ULiège (15)
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège (5)
GIGA-LRM - GIGA Cancer-Metastases Research Laboratory - ULiège (2)
GIGA‐R - Giga‐Research - ULiège (1)
Main Referenced Disciplines
Oncology (25)
Biochemistry, biophysics & molecular biology (19)
Gastroenterology & hepatology (2)
Laboratory medicine & medical technology (1)
Pharmacy, pharmacology & toxicology (1)

Publications (total 40)

The most downloaded
1209 downloads
Rademaker, G.* , Boumahd, Y.* , Peiffer, R., Anania, S., Wissocq, T., Liégeois, M., Luis, G., Sounni, N. E., Agirman, F., Maloujahmoum, N., De Tullio, P., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (July 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Redox Biology, 53, 102324. doi:10.1016/j.redox.2022.102324 https://hdl.handle.net/2268/289926

The most cited

64 citations (OpenAlex)

Costanza, B., Rademaker, G., Tiamiou, A., De Tullio, P., Leenders, J., Blomme, A., Bellier, J., Bianchi, E., Turtoi, A., Delvenne, P., Bellahcene, A., Peulen, O.* , & Castronovo, V.*. (2019). TGFBI, an ECM interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration. International Journal of Cancer. doi:10.1002/ijc.32247 https://hdl.handle.net/2268/233211

Lemaitre, F., Chakrama, F., O'Grady, T., Peulen, O., Rademaker, G., Deward, A., Chabot, B., Piette, J., Colige, A., Lambert, C., Dequiedt, F., & Habraken, Y. (30 May 2023). The transcription factor c-Jun mediates specific reprogramming of pre-mRNA splicing during platinum-based therapy via RBM39 [Poster presentation]. 28th Annual International Conference of the RNA society RNA 2023, Singapore.

Lemaitre, F.* , Chakrama, F.* , O'Grady, T., Peulen, O., Rademaker, G., Deward, A., Chabot, B., Piette, J., Colige, A., Lambert, C., Dequiedt, F.* , & Habraken, Y.*. (09 December 2022). The transcription factor c-Jun inhibits RBM39 to reprogram pre-mRNA splicing during genotoxic stress. Nucleic Acids Research, 50 (22), 12768 - 12789. doi:10.1093/nar/gkac1130
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Rademaker, G.* , Boumahd, Y.* , Peiffer, R., Anania, S., Wissocq, T., Liégeois, M., Luis, G., Sounni, N. E., Agirman, F., Maloujahmoum, N., De Tullio, P., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (July 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Redox Biology, 53, 102324. doi:10.1016/j.redox.2022.102324
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Boumahd, Y., Rademaker, G., Peiffer, R., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., & Peulen, O. (22 June 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells [Poster presentation]. EACR 2022.
Peer reviewed

Rademaker, G., Costanza, B., Pyr Dit Ruys, S., Peiffer, R., Agirman, F., Maloujahmoum, N., Vertommen, D., Turtoi, A., Bellahcene, A., Castronovo, V.* , & Peulen, O.*. (2022). Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination. Oncogenesis, 11, 42. doi:10.1038/s41389-022-00416-4
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Boumahd, Y., Rademaker, G., Peiffer, R., Anania, S., Gullo, C., Agirman, F., Maloujahmoum, N., Bellahcene, A., & Peulen, O. (2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Investigation on the involvement of STAT3 [Paper presentation]. GIGA Day 2022, Liège, Belgium.

Boumahd, Y., Rademaker, G., Peiffer, R., Anania, S., Maloujahmoum, N., Agirman, F., Bellahcene, A., & Peulen, O. (14 December 2021). Myoferlin targeting primes ferroptosis in pancreatic cancer cells [Poster presentation]. GIGA cancer day.

Dumont, E., De Bleye, C., Rademaker, G., Coic, L., Horne, J., Sacre, P.-Y., Peulen, O., Hubert, P., & Ziemons, E. (01 March 2021). Development of a prototype device for near real-time surface-enhanced Raman scattering monitoring of biological samples. Talanta, 224, 121866. doi:10.1016/j.talanta.2020.121866
Peer Reviewed verified by ORBi

Anania, S., Peiffer, R., Rademaker, G., Hego, A., Thiry, M., Deldicque, L., Francaux, M., Maloujahmoum, N., Agirman, F., Bellahcene, A., Castronovo, V., & Peulen, O. (21 June 2020). Myoferlin is a yet unknown interactor of the mitochondrial dynamics’ machinery in pancreas cancer cells. Cancers, 12 (6), 1643. doi:10.3390/cancers12061643
Peer Reviewed verified by ORBi

Bellier, J., Nokin, M.-J., Caprasse, M., Tiamiou, A., Blomme, A., Scheijen, J. L., KOOPMANSCH, B., MacKay, G. M., Chiavarina, B., Costanza, B., Rademaker, G., Durieux, F., Agirman, F., Maloujahmoum, N., Cusumano, P. G., LOVINFOSSE, P., Leung, H. Y., LAMBERT, F., Bours, V., ... Bellahcene, A. (04 February 2020). Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Reports, 30 (5), 1400-1416.e6. doi:10.1016/j.celrep.2020.01.012
Peer Reviewed verified by ORBi

Anania, S., Rademaker, G., Peiffer, R., Hego, A., Deldicque, L., Maloujahmoum, N., Agirman, F., Bellahcene, A., Castronovo, V., & Peulen, O. (February 2020). Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer [Poster presentation]. BACR Annual Meeting 2020 - Cancer metastases: from bedside to bench, Brussels, Belgium.

Rademaker, G. (30 January 2020). WJ460, a new drug targeting myoferlin, leads to ferroptosis and mitophagy in pancreatic cancer cells [Paper presentation]. 14th Meeting of the FRS-FNRS Contact Group on Oxidative Processes and Antioxidants.

Anania, S., Rademaker, G., Bellahcene, A., Castronovo, V., & Peulen, O. (December 2019). Role of myoferlin in mitochondrial dynamics and metabolic fitness of Pancreatic Ductal Adenocarcinoma [Poster presentation]. Second CIRM Scientific Day, Liège, Belgium.

Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (December 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic cancer cells by enhancing the migratory capacity through the control of oxidative phosphorylation [Poster presentation]. Cirm Annual meeting.

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (26 November 2019). Myoferlin depletion induces DNA damage response and p53- dependent cell cycle arrest and apoptosis in colon cancer [Poster presentation]. Metabolism in Cancer and Stromal Cells (2nd edition), Leuven, Belgium.

Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (November 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic cancer cells by enhancing the migratory capacity through the control of oxidative phosphorylation [Poster presentation]. Bioforum Uliège.

Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (23 October 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity Through the Control of Oxidative Phosphorylation [Poster presentation]. Pancreatic Cancer Symposium, Toulouse, France.

Anania, S., Rademaker, G., Wissocq, T., Bellahcene, A., Castronovo, V., & Peulen, O. (October 2019). Role of myoferlin in mitochondrial dynamics and metabolic fitness of PDAC [Poster presentation]. PANCREATIC CANCER SYMPOSIUM, Toulouse, France.

Costanza, B., Rademaker, G., Turtoi, A., Bellahcene, A., Castronovo, V., & Peulen, O. (October 2019). TGFBI, an ECM interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration [Poster presentation]. Pancreatic Cancer Symposium 2019, Toulouse, France.

Anania, S., Rademaker, G., Wissocq, T., Bellahcene, A., Castronovo, V., & Peulen, O. (06 September 2019). Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer [Poster presentation]. EDT Cancerology 2019, Bruxelles, Belgium.

Peulen, O., Rademaker, G., Anania, S., Turtoi, A., Bellahcene, A., & Castronovo, V. (August 2019). Ferlin overview: from membrane to cancer biology. Cells, 8, 954. doi:10.3390/cells8090954
Peer Reviewed verified by ORBi

Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (13 June 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity Through the Control of Oxidative Phosphorylation [Poster presentation]. Belgian Society for Cell and Developmental Biology - Spring Meeting, Liège, Belgium.

Rademaker, G., Costanza, B., Anania, S., Agirman, F., Maloujahmoum, N., Di Valentin, E., Goval, J.-J., Bellahcene, A., Castronovo, V., & Peulen, O. (June 2019). Myoferlin contributes to the metastatic phenotype of pancreatic cancer cells by enhancing their migratory capacity through the control of oxidative phosphorylation. Cancers, 11 (6). doi:10.3390/cancers11060853
Peer Reviewed verified by ORBi

Rademaker, G. (June 2019). Myoferlin Contributes to the Metastatic Phenotype of Pancreatic cancer cells by enhancing the migratory capacity through the control of oxidative phosphorylation [Paper presentation]. Giga Cancer Seminar.

Costanza, B., Rademaker, G., Tiamiou, A., De Tullio, P., Leenders, J., Blomme, A., Bellier, J., Bianchi, E., Turtoi, A., Delvenne, P., Bellahcene, A., Peulen, O.* , & Castronovo, V.*. (2019). TGFBI, an ECM interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration. International Journal of Cancer. doi:10.1002/ijc.32247
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., CHARLOTEAUX, B., Verbeke, L., van Laere, S., RONCARATI, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21(1, 11. doi:10.1186/s13058-018-1095-7
Peer Reviewed verified by ORBi

Rademaker, G. (2019). Human colon cancer overexpress myoferlin to maintain a fit mitochondrial network and escape p53 dependent apoptosis [Paper presentation]. EDT Biologie Moléculaire.

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Peiffer, R., Agirman, F., Maloujahmoum, N., Habraken, Y., Delvenne, P., Bellahcene, A., Castronovo, V.* , & Peulen, O.*. (2019). Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis. Oncogenesis. doi:10.1038/s41389-019-0130-6
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (2019). Human colon cancer overexpress myoferlin to maintain a fit mitochondrial network and escape p53 dependent apoptosis [Poster presentation]. Belgian Association for Cancer Research Congress, Anvers, Belgium.

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Herfs, M., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (01 July 2018). Myoferlin controls mitochondrial structure and metabolism in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness [Poster presentation]. EACR 25 50 Years, Amsterdam, Netherlands.

Rademaker, G., Hennequière, V., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Bettendorff, L., Deroanne, C., Thiry, M., Delvenne, P., Hustinx, R., Bellahcene, A., Castronovo, V., & Peulen, O. (April 2018). Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene, 37 ((32)), 4398-4412. doi:10.1038/s41388-018-0287-z
Peer Reviewed verified by ORBi

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., Bellier, J., Costanza, B., Herfs, M., Bettendorff, L., Deroanne, C., Delvenne, P., HUSTINX, R., Bellahcene, A., Castronovo, V., & Peulen, O. (2018). Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma and affects tumor aggressiveness [Poster presentation]. Bioforum Uliège.

Rademaker, G. (2018). Myoferlin controls mitochondrial structure and activity in pancreatic cancer and affects tumor aggressiveness [Paper presentation]. Giga Cancer ULiège.

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Anania, S., Bettendorff, L., Deroanne, C., Thiry, M., Delvenne, P., HUSTINX, R., Bellahcene, A., Castronovo, V., & Peulen, O. (2018). Myoferlin controls mitochondrial structure and activity in pancreatic cancer and affects tumor aggressiveness [Poster presentation]. Belgian Association for Cancer Research Congress.

Rademaker, G., Costanza, B., Bellier, J., Herfs, M., Agirman, F., Maloujahmoum, N., Bellahcene, A., Castronovo, V., & Peulen, O. (2018). Myoferlin depletion induces DNA damage response and p53 dependent cell cycle arrest and apoptosis in colon cancer [Poster presentation]. Third Symposium of UBRC, Bruxelles, Belgium.

Rademaker, G. (2018). Myoferlin depletion induces DNA damage response and p53 dependent cell cycle arrest and apoptosis in colon cancer [Paper presentation]. Giga Cancer Day.

Rademaker, G., Hennequière, V., Brohée, L., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Bettendorff, L., Deroanne, C., Delvenne, P., Hustinx, R., Bellahcene, A., Castronovo, V., & Peulen, O. (22 September 2017). Myoferlin controls mitochondrial structure in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness [Poster presentation]. Second U-CRC Symposium, Bruxelles, Belgium.

Rademaker, G. (June 2017). Myoferlin a key protein in mitochondrial function, the case of pancreatic cancer [Paper presentation]. Giga-Cancer.

Rademaker, G., Hennequière, V., Peixoto, P., Bellahcene, A., Castronovo, V., & Peulen, O. (01 February 2017). Myoferlin, a new autophagy player in pancreatic cancer cells [Poster presentation]. Giga-Day, Liège, Belgium.

Rademaker, G. (2016). Validation of a Multiplex HPLC MS/MS assay for the measurement of steroid hormones [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/211494

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