In vitro approach to evaluate the fermentation pattern of inulin-rich food in obese individuals.

[en] Alterations of the gut microbiome have been associated with obesity and metabolic disorders. The gut microbiota can be influenced by the intake of dietary fibres with prebiotic properties, such as inulin-type fructans. This study tested the hypothesis that obese individuals subjected for 12 weeks to a inulin-enriched versus inulin-poor diet have differential faecal fermentation patterns. The fermentation of cellulose and inulin hydrolysates, of six different inulin-rich and inulin-poor vegetables of both groups was analysed in vitro on faecal inocula. The results showed that the microbiota from obese patients who received fructan-rich diet for three weeks produce more gas and total short-chain fatty acid (SCFA) compared to the microbiota taken of the same individuals before the treatment. Obese individuals fed with a low-fructan diet produce less gas and less SCFA compared to the treated group. This study highlighted profound changes in microbiota fermentation capacity obtained by prebiotic intervention in obese individuals, which favors the production of specific bioactive metabolites.

Disciplines :

Agriculture & agronomy

Author, co-author :

Kalala Bolokango, Gaetan ; Université de Liège - ULiège > Form. doct. sc. agro. & ingé. biol. (paysage)

Kambashi, Bienvenu

Taminiau, Bernard ; Université de Liège - ULiège > Département de sciences des denrées alimentaires (DDA) > Microbiologie des denrées alimentaires

Schroyen, Martine ; Université de Liège - ULiège > Département GxABT > Département GxABT

Everaert, Nadia ; Université de Liège - ULiège > Département GxABT > Ingénierie des productions animales et nutrition

Beckers, Yves ; Université de Liège - ULiège > Département GxABT > Ingénierie des productions animales et nutrition

Richel, Aurore ; Université de Liège - ULiège > Département GxABT > SMARTECH

Njeumen Lemotio, Georges Patrick

Pachikian, Barbara

Neyrinck, Audrey M.

More authors (7 more)

Language :

English

Title :

In vitro approach to evaluate the fermentation pattern of inulin-rich food in obese individuals.

Publication date :

2019

Journal title :

British Journal of Nutrition

ISSN :

0007-1145

eISSN :

1475-2662

Pages :

1-19

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 17 February 2020

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