Profil

Tits Monique

Département de pharmacie

See author's contact details
Main Research Fields
Pharmacy, pharmacology & toxicology
Phytobiology (plant sciences, forestry, mycology...)
Chemistry
Biochemistry, biophysics & molecular biology
Anatomy (cytology, histology, embryology...) & physiology
Main Keywords
Strychnos variabilis; Plasmodium falciparum; Ribes nigrum; prodelphinidins; Strychnos usambarensis;
Main Unit & Research Centers
Centre Interfacultaire de Recherche du Médicament (C.I.R.M.)
Centre Interfacultaire de Recherche du Médicament - CIRM
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
CIRM - Laboratoire de Pharmacognosie - Laboratoire de chimie médicale
CORD - Centre de l'Oxygène, Recherche et Développement - ULiège
Main Co-authors
Angenot, Luc 
Frederich, Michel 
Wauters, Jean-Noël 
De Mol, Patrick 
Penelle, Jacques

Publications (total 208)

The most downloaded
2014 downloads
Tits, M. (March 2010). Place et importance de la Phytothérapie en thérapeutique moderne. Paper presented at Plantes médicinales et aromatiques, Oujda, Morocco. https://hdl.handle.net/2268/156944
The most cited
184 citations (SCOPUS)
Bonjean, K., De Pauw-Gillet, M.-C., Defresne, M.-P., Colson, P., Houssier, C., Dassonneville, L., Bailly, C., Greimers, R., Wright, C., Quetin-Leclercq, J., Tits, M., & Angenot, L. (1998). The DNA intercalating alkaloid cryptolepine interferes with topoisomerase II and inhibits primarily DNA synthesis in B16 melanoma cells. Biochemistry, 37 (15), 5136-46. doi:10.1021/bi972927q https://hdl.handle.net/2268/39293

Stankovic, M., Baptista, P., Carillo, P., Păltine, R., Ielciu, I.* , Hangan, D., Nicula, M., Pa, E., Angenot, L., Tits, M., Moca, A., Babotă, M., Frumuzachi, O., Tămaş, M., Crişan, G., & Frederich, M. (2022). Biological Activities of Some Isoquinoline Alkaloids from Fumaria schleicheri Soy. Will. Plants. doi:10.3390/plants11091202
Peer Reviewed verified by ORBi

Kapepula, P. M., Mungitshi, P. M., Tshitenge, D. T., Franck, T., Ngoyi, D. M., Kalenda, P. D. T., Tits, M., Frederich, M., Ngombe, N. K., & Mouithys-Mickalad, A. (2021). Microscopic Characteristics , Chromatographic Profiles and Inhibition of Peroxidase Activity of the Leaves of Manihot esculenta and Manihot glaziovii , Consumed as Traditional Vegetables. Journal of Biosciences and Medicines, 9, 59--73. doi:10.4236/jbm.2021.99006
Peer reviewed

Muganga, R., Bero, J., Quetin-Leclercq, J., Angenot, L., Tits, M., Mouithys-Mickalad, A., Franck, T., & Frederich, M. (2020). In vitro Antileishmanial, Antitrypanosomal, and Anti-inflammatory- like Activity of Terminalia mollis Root Bark. Planta Medica, efirst. doi:10.1055/a-1260-6382
Peer Reviewed verified by ORBi

Ielciu, I.-I., Mouithys-Mickalad, A., Franck, T., Angenot, L., Ledoux, A., Păltinean, R., Cieckiewicz, E., Etienne, D., Tits, M., Crişan, G., & Frederich, M. (2019). Flavonoid composition, cellular antioxidant activity and (myelo)peroxidase inhibition of a Bryonia alba L. (Cucurbitaceae) leaves extract. Journal of Pharmacy and Pharmacology, 71, 230-239. doi:10.1111/jphp.13025
Peer Reviewed verified by ORBi

Assaidi, A., Dib, I., Tits, M., Angenot, L., Bellahcen, S., Bouanani, N., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., Frederich, M., & Ziyyat, A. (2019). Chenopodium ambrosioides induces an endothelium-dependent relaxation of rat isolated aorta. Journal of Integrative Medicine, 17 (2), 115 - 124. doi:10.1016/j.joim.2019.01.006
Peer reviewed

Tits, M., & Angenot, L. (2017). Rembert Dodoens (1517-1585) Histoire des plantes Traduction française suivie d'un petit recueil par Charles de l'Escluse. In F. Libert, C. Charles, & Y. Poumay (Ed.), Balade patrimoniale en médecine, pharmacie et sciences biomédicales (pp. 58-61). Namur, Belgium: Presses universitaires de Namur.

Dib, I., Angenot, L., Ziyyat, A., & Tits, M. (March 2017). Artemisia campestris L.:Ethnomedical, phytochemical and pharmacological review. Journal of Herbal Medicine, 7 (1), 1-10. doi:10.1016/j.hermed.2016.10.005
Peer Reviewed verified by ORBi

Dib, I., Tits, M., Angenot, L., Wauters, J. N., Assaidi, A., Mekhfi, H., Aziz, M., Bnouham, M., Legssyer, A., Frederich, M., & Ziyyat, A. (2017). Antihypertensive and vasorelaxant effects of aqueous extract of Artemisia campestris L. from Eastern Morocco. Journal of Ethnopharmacology, 206, 224-235. doi:10.1016/j.jep.2017.05.036
Peer Reviewed verified by ORBi

Jansen, O., Tchinda, A. T., Loua, J., Esters, V., Cieckiewicz, E., Ledoux, A., Toukam, P. D., Angenot, L., Tits, M., Balde, A. M., & Frederich, M. (2017). Antiplasmodial activity of Mezoneuron benthamianum leaves and identification of its active constituents. Journal of Ethnopharmacology, 203 (March), 20--26. doi:10.1016/j.jep.2017.03.021
Peer Reviewed verified by ORBi

Kapepula, P. M., Kabamba Ngombe, N., Tshisekedi Tshibangu, P., Tsumbu, C., Franck, T., Mouithys-Mickalad, A., Mumba, D., Tshala-Katumbay, D., Serteyn, D., Tits, M., Angenot, L., Kalenda, P. D. T., & Frederich, M. (2017). Comparison of metabolic profiles and bioactivities of the leaves of three edible Congolese Hibiscus species. Natural Product Research, 6419 (March), 1--8. doi:10.1080/14786419.2017.1305382
Peer Reviewed verified by ORBi

Tshisekedi Tshibangu, P., Mutwale Kapepula, P., Kabongo Kapinga, M. J., Tujibikila Mukuta, A., Kalenda, D. T., Tchinda, A. T., Mouithys-Mickalad, A., Jansen, O., Cieckiewicz, E., Tits, M., Angenot, L., & Frederich, M. (2017). Antiplasmodial activity of Heinsia crinita (Rubiaceae) and identification of new iridoids. Journal of Ethnopharmacology, 196, 261-266. doi:10.1016/j.jep.2016.11.041
Peer Reviewed verified by ORBi

Mskhiladze, L., Chincharadze, D., St-Gelais, A., Mshvildadze, V., Pichette, A., Ledoux, A., Tits, M., & Frederich, M. (July 2016). Isolation and Identification of Steroid and Flavonoid Glycosides from the Flowers of Allium gramineum. International Journal of Pharmaceutical Sciences and Drug Research, 8 (4), 240-243.
Peer reviewed

Tchinda Tiabou, A., Loua, J., Esters, V., Cieckiewicz, E., Ledoux, A., Angenot, L., Tits, M., Baldé, A. M., Frederich, M., & Jansen, O. (July 2016). Study of Mezoneuron benthamianum, a plant traditionally used against malaria in Guinea. Poster session presented at 9th Joint Natural Products Conference 2016 Copenhagen, Copenhagen, Denmark.

Tshisekedi Tshibangu, P., Mutwale Kapepula, P., Kabongo Kapinga, M. J., Kabika Lupona, H., Kabamba Ngombe, N., Dibungi T. Kalenda, P., Jansen, O., Wauters, J.-N., Tits, M., Angenot, L., Rozet, E., Hubert, P., Marini Djang'Eing'A, R., & Frederich, M. (09 June 2016). Fingerprinting and validation of a LC-DAD method for the analysis of biflavanones in Garcinia kola-based antimalarial improved traditional medicines. Journal of Pharmaceutical and Biomedical Analysis, 128 (2016), 382-390. doi:10.1016/j.jpba.2016.04.042
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Mutwale Kapepula, P., Mbombo Mungitshi, P., Franck, T., Mouithys-Mickalad, A., Mumba Ngoyi, D., Kalenda, P. D. T., Kabamba Ngombe, N., Serteyn, D., Tits, M., Frederich, M., & Tamfum Muyembe, J.-J. (2016). Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo. Natural Product Research, 1-4. doi:10.1080/14786419.2016.1263844
Peer Reviewed verified by ORBi

Paltinean, R., Toiu, A., Wauters, J.-N., Frederich, M., Tits, M., Angenot, L., Tamas, M., & Crisan, G. (2016). PHYTOCHEMICAL ANALYSIS OF FUMARIA OFFICINALIS L. (FUMARIACEAE). Farmacia, 64 (3), 409-413.
Peer reviewed

Ielciu, I.-I., Frederich, M., Tits, M., Angenot, L., Paltinean, R., Cieckiewicz, E., Crisan, G., & Vlase, L. (2016). BRYONIA ALBA L. AND ECBALLIUM ELATERIUM (L.) A. RICH. - TWO RELATED SPECIES OF THE CUCURBITACEAE FAMILY WITH IMPORTANT PHARMACEUTICAL POTENTIAL. Farmacia, 64 (3), 323-332.
Peer reviewed

Ielciu, I.-I., Păltinean, R., Cieckiewicz, E., Wauters, J.-N., Tits, M., Crişan, G., Vlase, L., & Frederich, M. (14 October 2015). HPLC-DAD IDENTIFICATION OF SOME FLAVONOIDS FROM THE LEAVES AND AERIAL PARTS OF BRYONIA ALBA L. SPECIES SPONTANEOUS IN THE ROMANIAN FLORA. Poster session presented at 2nd International Conference on Natural Products Utilization: From Plants to Pharmacy Shelf, Plovdiv, Bulgaria.

Ledoux, A., Martin, B., De Tullio, P., Tits, M., Wauters, J.-N., Choi, Y. H., Bodson, M., & Frederich, M. (16 July 2015). Metabolomics analysis of Galium odoratum (L.) Scop.: impact of the plant population origin and growth conditions. Poster session presented at 2ème Symposium international AFERP – STOLON, Lyon, France.

Martin, B., Frederich, M., De Tullio, P., Tits, M., Wauters, J.-N., Choi, & Bodson, M. (June 2015). Metabolomics analysis of Galium odoratum (L.) Scop.: impact of the plant population origin and growth conditions. Current Metabolomics, 3.
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Mskhiladze, L., Chincharadze, D., Tits, M., Wauters, J.-N., Bellahcene, A., Castronovo, V., Mouithys-Mickalad, A., Franck, T., & Frederich, M. (2015). Identification of Cytotoxic and Antioxidant Compounds from Allium gramineum Flowers. International Journal of Pharmaceutical Sciences and Drug Research, 7, 78-82.
Peer reviewed

Tshisekedi Tshibangu, P., Kalenda Dibungi, P., Rozet, E., Marini Djang'Eing'A, R., Tits, M., & Frederich, M. (June 2014). INVESTIGATION OF TWO IMPROVED TRADITIONAL MEDICINES: DEVELOPMENT AND VALIDATION OF A LC-UV METHOD FOR THE DOSAGE OF A TRACER COMPOUND. Poster session presented at 10th International Symposium on Drug Analysis / 25th International Symposium on Pharmaceutical and Biomedical Analysis, Liège, Belgium.

Muganga, R., Angenot, L., Tits, M., & Frederich, M. (2014). In Vitro and In Vivo Antiplasmodial Activity of Three Rwandan Medicinal Plants and Identification of Their Active Compounds. Planta Medica, 80 (6), 482-489. doi:10.1055/s-0034-1368322
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Jansen, O., Nyemb, J.-N., Tits, M., Dive, G., Angenot, L., & Frederich, M. (2014). Strychnobaillonine, an Unsymmetrical Bisindole Alkaloid with an Unprecedented Skeleton from Strychnos icaja Baill. Roots. Journal of Natural Products, 77, 1078-1082.
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zidane, A., Tits, M., Angenot, L., Wauters, J.-N., Frederich, M., Dib, I., Mekhfi, H., Aziz, M., Bnouham, M., Abdelkhaleq, L., & Ziyyat, A. (2014). Phytochemical analysis of Tetraclinis articula in relation to its vasorelaxant property. Journal of Materials and Environmental Science, 5 (5), 1368-1375.
Peer Reviewed verified by ORBi

Getia, M., Mshvildadze, V., Dekanosidze, G., Wauters, J.-N., Tits, M., & Frederich, M. (17 June 2013). Some natural products from aerial parts of Scrophularia imerethica. Poster session presented at International Symposium on Medicinal plants and Natural Product, Montreal, Canada.

Tits, M. (30 May 2013). Produits d’hémisynthèse, inspirés de substances naturelles, utilisés en thérapeutique. Paper presented at Premières Journées des Produits synthétiques d'intérêt thérapeutique, Oujda, Morocco.

Esters, V., Karangwa, C., Tits, M., Francotte, P., Pirotte, B., Servais, A.-C., Fillet, M., Crommen, J., Robbrecht, E., MINET, A., Grisar, T., Angenot, L., & Frederich, M. (March 2013). Unusual Amino Acids and Monofluoroacetate from Dichapetalum michelsonii (Umutambasha), a Toxic Plant from Rwanda. Planta Medica, 79, 334-337. doi:10.1055/s-0032-1328283
Peer Reviewed verified by ORBi

Jonville, M.-C., Dive, G., Angenot, L., Bero, J., Tits, M., Ollivier, E., & Frederich, M. (2013). Dimeric bisindole alkaloids from the stem bark of Strychnos nux-vomica L. Phytochemistry, 87, 157-163. doi:10.1016/j.phytochem.2012.11.002
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bournine, L., Bensalem, S., Wauters, J.-N., Iguer-Ouada, M., Maiza-Benabdesselam, F., Bedjou, F., Castronovo, V., Bellahcene, A., Tits, M., & Frederich, M. (2013). Identification and Quantification of the Main Active Anticancer Alkaloids from the Root of Glaucium flavum. International Journal of Molecular Sciences, 14, 23533-23544. doi:10.3390/ijms141223533
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Mangwala Kimpende, P., Lusakibanza, M., Mesia, K., Tona, L., Tits, M., Angenot, L., Frederich, M., & Van Meervelt, L. (2013). Isolation, pharmacological activity and structure determination of physalin B and 5[beta],6[beta]-ep­oxy­physalin B isolated from Congolese Physalis angulata L. Acta Crystallographica. Section C, Structural Chemistry, C69, 1557-1562. doi:10.1107/S010827011303117X
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Bournine, L., Bensalem, S., Peixoto, P., Gonzalez, A., Maiza-Benabdesselam, F., Bedjou, F., Wauters, J.-N., Tits, M., Frederich, M., Castronovo, V., & Bellahcene, A. (2013). Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine, 20 (13), 1211-1218. doi:10.1016/j.phymed.2013.06.007
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Paltinean, R., Toju, A., Wauters, J.-N., Frederich, M., Tits, M., Angenot, L., Tamas, M., & Crisan, G. (2013). Identification and determination of alkaloids in Fumaria Species from Romania. Digest Journal of Nanomaterials and Biostructures, 8 (2), 817-824.
Peer Reviewed verified by ORBi

Paltinean, R., Wauters, J.-N., Tits, M., Frederich, M., Angenot, L., Mircea, T., & Crisan, G. (2013). Comparative morphological studies on some species of the genus Fumaria. Farmacia, 61 (2), 371-377.
Peer reviewed

Harnafi, H., Ramchoun, M., Tits, M., Wauters, J.-N., Frederich, M., Angenot, L., Aziz, M., Alem, C., & Amrani, S. (2013). Phenolic acid-rich extract of sweet basil restores cholesterol and triglycerides metabolism in high fat diet-fed mice: A comparison with fenofibrate. Biomedicine and Preventive Nutrition, 3 (4), 393-397. doi:10.1016/j.bionut.2013.03.005
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Jonville, M., Angenot, L., Tits, M., & Frederich, M. (August 2012). Bisindolomonoterpenic alkaloids from the stem bark of Strychnos nux-vomica exhibiting antiplasmodial activity. Planta Medica, 78 (11), 1047.
Peer Reviewed verified by ORBi

Tshisekedi Tshibangu, P., Kalenda Dibungi T., P., Wauters, J.-N., Tits, M., Frederich, M., Rozet, E., Hubert, P., & Marini Djang'Eing'A, R. (July 2012). DEVELOPMENT AND VALIDATION OF A LC-UV METHOD FOR THE DOSAGE OF A TRACER IN AN IMPROVED TRADITIONAL MEDICINE. Paper presented at Symposium sur les médicaments traditionnels antipaludiques et l’analyse des médicaments et des toxiques, Butare, Rwanda.

Kalume, Losson, B., Angenot, L., Tits, M., Wauters, J.-N., Frederich, M., & Saegerman, C. (2012). Rotenoid content and in vitro acaricidal activity of Tephrosia vogelii leaf extract on the tick Rhipicephalus appendiculatus. Veterinary Parasitology, 190 (1-2), 204-209. doi:10.1016/j.vetpar.2012.06.015
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Jansen, O., Tits, M., Angenot, L., Nicolas, J.-P., De Mol, P., Nikiema, J.-B., & Frederich, M. (2012). Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15- O-acetate as the main active compound. Malaria Journal, 11 (1), 289 (1-9. doi:10.1186/1475-2875-11-289
Peer Reviewed verified by ORBi

Tsumbu, C. N., Dupont, G., Tits, M., Angenot, L., Frederich, M., Kohnen, S., Mouithys-Mickalad, A., Serteyn, D., & Franck, T. (2012). Polyphenol Content and Modulatory Activities of Some Tropical Dietary Plant Extracts on the Oxidant Activities of Neutrophils and Myeloperoxidase. International Journal of Molecular Sciences, 13 (1), 628-650. doi:10.3390/ijms13010628
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Zeraik, M. L., Yariwake, J., Wauters, J.-N., Tits, M., & Angenot, L. (2012). Analysis of Passion Fruit Rinds (Passiflora edulis): Isoorientin Quantification by HPTLC and Evaluation of Antioxidant ( Radical Scavenging) Capacity. Quimica Nova, 35 (3), 541-545. doi:10.1590/S0100-40422012000300019
Peer Reviewed verified by ORBi

Cao, M., Muganga, R., Nistor, I., Tits, M., Angenot, L., & Frederich, M. (2012). LC–SPE–NMR–MS analysis of Strychnos usambarensis fruits from Rwanda. Phytochemistry Letters, 5 (0), 170-173. doi:10.1016/j.phytol.2011.12.003
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Cao, M., Muganga, R., Tits, M., Angenot, L., & Frederich, M. (13 December 2011). 17-O-Actetyl-10-hydroxycorynantheol, a selective antiplasmodial alkaloid isolated from Strychnos usambarensis leaves. Paper presented at 50th Anniversary Meeting of Phytochemical Society of North America, Kohala Coast, United States - Hawaii.

Tsumbu, C. N., Deby-Dupont, G., Tits, M., Angenot, L., Franck, T., Serteyn, D., & Mouithys-Mickalad, A. (16 September 2011). Antioxidant and Antiradical Activities of Manihot esculenta Crantz (Euphorbiaceae) Leaves and Other Selected Tropical Green Vegetables Investigated on Lipoperoxidation and Phorbol-12-myristate-13-acetate (PMA) Activated Monocytes. Nutrients, 3 (9), 818-838. doi:10.3390/nu3090818
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Zeraik, M.-L., Serteyn, D., Deby-Dupont, G., Wauters, J.-N., Tits, M., Yariwake, J., Angenot, L., & Franck, T. (15 September 2011). Evaluation of the antioxidant activity of passion fruit (Passiflora edulis and Passiflora alata) extracts on stimulated neutrophils and myeloperoxidase activity assays. Food Chemistry, 128, 259-265. doi:10.1016/j.foodchem.2011.03.001
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Cao, M., Muganga, R., Tits, M., Angenot, L., & Frederich, M. (August 2011). 17-O-Acetyl,10-hydroxycorynantheol, a Selective Antiplasmodial Alkaloid Isolated from Strychnos usambarensis Leaves. Planta Medica, 77, 2050-2053. doi:10.1055/s-0031-1280124
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Cao, M., Muganga, R., Tits, M., Angenot, L., & Frederich, M. (13 May 2011). 17-O-acetyl, 10-hydroxycorynantheol, a selective antiplasmodial alkaloid isolated from Strychnos usambarensis leaves. Paper presented at 15th Forum of Pharmaceutical Sciences, Spa, Belgium.

Frederich, M., Tits, M., & Angenot, L. (2011). Pharmacognosie volume III. (Les éditions de l'Université de Liège, PHAR0332-1 Pharmacognosie (Partim II)).

Frederich, M., Wauters, J.-N., Tits, M., Jason, C., De Tullio, P., Van der Heyden, Y., Fan, G., & Angenot, L. (2011). Quality Assessment of Polygonum cuspidatum and Polygonum multiflorum by 1H NMR Metabolite Fingerprinting and Profiling Analysis. Planta Medica, 77, 81-86. doi:10.1055/s-0030-1250132
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (2011). Pharmacognosie volume II. (Les éditions de l'Université de Liège, PHAR0332-1 Pharmacognosie (Partim II)).

Cao, M., Tits, M., Muganga, R., Angenot, L., & Frederich, M. (September 2010). LC-SPE-NMR-MS analysis of Strychnos usambarensis fruits from Rwanda. Planta Medica, 76 (12), 1241-1242.
Peer Reviewed verified by ORBi

Yariwake, J., Zeraik, M., Serteyn, D., Deby-Dupont, G., Wauters, J.-N., Tits, M., Angenot, L., & Franck, T. (September 2010). Antioxidant activity of Passiflora edulis and Passiflora alata fruits. Planta Medica, 76 (12), 1274-1275.
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (2010). Pharmacognosie volume I. (PHAR0331-2 Pharmacognosie (Partim I)). Liège, Belgium: Editions de l'Université de Liège.

Tits, M. (March 2010). Place et importance de la Phytothérapie en thérapeutique moderne. Paper presented at Plantes médicinales et aromatiques, Oujda, Morocco.

Lusakibanza, M., Mesia, G., Tona, G., Karemere, S., Lukuka, A., Tits, M., Angenot, L., & Frederich, M. (2010). In vitro and in vivo antimalarial and cytotoxic activity of five plants used in Congolese traditional medicine. Journal of Ethnopharmacology, 129, 398-402. doi:10.1016/j.jep.2010.04.007
Peer Reviewed verified by ORBi

Angenot, L., Tits, M., & Frederich, M. (2010). Pharmacognosie - Volume 2. (ULiège - Université de Liège, PHAR0332-1). Liège, Belgium: Les éditions de l'Université de Liège.

Angenot, L., Tits, M., & Frederich, M. (2010). Pharmacognosie Volume 3. (ULiège - Université de Liège, PHAR0332-1). Liège, Belgium: ULg - Université de Liège.

Jansen, O., Angenot, L., Tits, M., Nicolas, J. P., De Mol, P., Nikiéma, J. B., & Frederich, M. (2010). Evaluation of 13 selected medicinal plants from Burkina Faso for their antiplasmodial properties. Journal of Ethnopharmacology, 130, 143-150. doi:10.1016/j.jep.2010.04.032
Peer Reviewed verified by ORBi

Muganga, R., Angenot, L., Tits, M., & Frederich, M. (2010). Antiplasmodial and cytotoxic activities of Rwandan medicinal plants used in the treatment of malaria. Journal of Ethnopharmacology, 128, 52-55. doi:10.1016/j.jep.2009.12.023
Peer Reviewed verified by ORBi

Frederich, M., Jansen, C., De Tullio, P., Tits, M., Demoulin, V., & Angenot, L. (2010). Metabolomic analysis of Echinacea spp. by (1)H nuclear magnetic resonance spectrometry and multivariate data analysis technique. Phytochemical Analysis, 21 (1), 61-65. doi:10.1002/pca.1156
Peer Reviewed verified by ORBi

Jansen, O., Nikiéma, J.-B., Angenot, L., Tits, M., Nicolas, J.-P., De Mol, P., & Frederich, M. (07 October 2009). Evaluation des potentialités antiplasmodiales de plantes utilisées en médecine traditionnelle au Burkina Faso. Paper presented at 2eme rencontre Internationale de Phytothérapie de Ouagadougou, Ouagadougou, Burkina Faso.

Angenot, L., & Tits, M. (2009). Pharmacognosie Volume 1. (ULiège - Université de Liège, PHAR-0331-2). Liège, Belgium: Les Editions de l'Université de Liège.

Ouattara, B., Jansen, O., Angenot, L., Guissou, P., Frederich, M., Fondu, P., & Tits, M. (March 2009). Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae). Phytomedicine, 16 (2-3), 125-129. doi:10.1016/j.phymed.2008.10.013
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Karangwa, C., Esters, V., Frederich, M., Tits, M., Kadima, J. N., Damas, J., Noirfalise, A., & Angenot, L. (2009). Erratum to “Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp. montana” [J. Ethnopharmacol. 103 (2006) 433–438]. Journal of Ethnopharmacology, 125, 503. doi:10.1016/j.jep.2009.06.035
Peer Reviewed verified by ORBi

Jansen, O., Frederich, M., Tits, M., Angenot, L., Cousineau, S., Bessot, L., Crunet, C., & Nicolas, J.-P. (July 2008). Ethnopharmacologie et paludisme au Burkina Faso : sélection de 13 espèces à potentialités antiplasmodiales méconnues. Ethnopharmacologia, 41, 74-81.
Peer reviewed

Frederich, M., Tits, M., & Angenot, L. (January 2008). Potential antimalarial activity of indole alkaloids. Transactions of the Royal Society of Tropical Medicine and Hygiene, 102 (1), 11-19. doi:10.1016/j.trstmh.2007.10.002
Peer Reviewed verified by ORBi

Jansen, O., Angenot, L., Tits, M., Nicolas, J.-P., De Mol, P., Sacré, P.-Y., Jonville, M., & Frederich, M. (2008). In vitro antiplasmodial activity of ethnobotanically selected plants from Burkina Faso. Planta Medica, 74 (9), 1142-1142.
Peer Reviewed verified by ORBi

Frederich, M., Jansen, C., De Tullio, P., Demoulin, V., Tits, M., & Angenot, L. (2008). Metabolomic analysis of Echinacea sp. by H-1 Nuclear magnetic resonance spectrometry and multivariate analysis techniques. Planta Medica, 74 (9), 1089-1089.
Peer Reviewed verified by ORBi

Jokhadze, M., Eristavi, L., Kutchukhidze, J., Chariot, A., Angenot, L., Tits, M., Jansen, O., & Frederich, M. (July 2007). In vitro cytotoxicity of some medicinal plants from Georgian amaryllidaceae. Phytotherapy Research, 21 (7), 622-624. doi:10.1002/ptr.2130
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Karangwa, C., Esters, V., Tits, M., Minet, A., Boland, A., Seutin, V., Noirfalise, A., Angenot, L., Grisar, T., & Foidart, A. (15 June 2007). Characterization of the neurotoxicity induced by the extract of Magnistipula butayei (Chrysobalanaceae) in rat: Effects of a new natural convulsive agent. Toxicon, 49 (8), 1109-1119. doi:10.1016/j.toxicon.2007.02.001
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Philippe, G., De Mol, P., Angenot, L., Tits, M., & Frederich, M. (May 2007). In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from Strychnos icaja. Planta Medica, 73 (5), 478-479. doi:10.1055/s-2007-967174
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Frederich, M., Philippe, G., Tits, M., & Angenot, L. (2007). Potentialités antipaludiques des alcaloïdes indoliques. Actualités de Chimie Thérapeutique, 33, 1-32.

Jansen, O., Akhmedjanova, V., Angenot, L., Balansard, G., Chariot, A., Ollivier, E., Tits, M., & Frederich, M. (21 April 2006). Screening of 14 alkaloids isolated from Haplophyllum A. Juss. for their cytotoxic properties. Journal of Ethnopharmacology, 105 (1-2), 241-245. doi:10.1016/j.jep.2005.11.001
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Esters, V., Angenot, L., Brandt, V., Frederich, M., Tits, M., Van Nerum, C., Wauters, J.-N., & Hubert, P. (21 April 2006). Validation of a high-performance thin-layer chromatography/densitometry method for the quantitative determination of glucosamine in a herbal dietary supplement. Journal of Chromatography. A, 1112 (1-2), 156-164. doi:10.1016/j.chroma.2006.01.035
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Karangwa, C., Esters, V., Frederich, M., Tits, M., Kadima, J. N., Damas, J., Noirfalise, A., & Angenot, L. (February 2006). Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp montana. Journal of Ethnopharmacology, 103 (3), 433-438. doi:10.1016/j.jep.2005.08.019
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Philippe, G., Nguyen, L., Angenot, L., Frederich, M., Moonen, G., Tits, M., & Rigo, J.-M. (13 January 2006). Study of the interaction of antiplasmodial strychnine derivatives with the glycine receptor. European Journal of Pharmacology, 530 (1-2), 15-22. doi:10.1016/j.ejphar.2005.11.048
Peer Reviewed verified by ORBi

Philippe, G., Angenot, L., De Mol, P., Goffin, E., Hayette, M.-P., Tits, M., & Frederich, M. (21 March 2005). In vitro screening of some Strychnos species for antiplasmodial activity. Journal of Ethnopharmacology, 97 (3), 535-539. doi:10.1016/j.jep.2004.12.011
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Garbacki, N., Tits, M., Angenot, L., & Damas, J. (21 October 2004). Inhibitory Effects of Proanthocyanidins from Ribes Nigrum Leaves on Carrageenin Acute Inflammatory Reactions Induced in Rats. BMC Pharmacology, 4 (1), 1-9. doi:10.1186/1471-2210-4-25
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Philippe, G., Angenot, L., Tits, M., & Frederich, M. (15 September 2004). About the toxicity of some Strychnos species and their alkaloids. Toxicon, 44 (4), 405-416. doi:10.1016/j.toxicon.2004.05.006
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Frederich, M., Tits, M., Goffin, E., Philippe, G., Grellier, P., De Mol, P., Hayette, M.-P., & Angenot, L. (June 2004). In vitro and in vivo antimalarial properties of isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis. Planta Medica, 70 (6), 520-525. doi:10.1055/s-2004-827151
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Ouattara, B., Angenot, L., Guissou, P., Fondu, P., Dubois, J., Frederich, M., Jansen, O., Van Heugen, J.-C., Wauters, J.-N., & Tits, M. (April 2004). LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam. Phytochemistry, 65 (8), 1145-1151. doi:10.1016/j.phytochem.2004.02.025
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Frederich, M., Cristino, A., Choi, Y. H., Verpoorte, R., Tits, M., Angenot, L., Prost, E., Nuzillard, J.-M., & Zèches-Hanrot, M. (January 2004). Chrysopentamine, an antiplasmodial anhydronium base from Strychnos usambarensis leaves. Planta Medica, 70 (1), 72-76. doi:10.1055/s-2004-815461
Peer Reviewed verified by ORBi

Pereira, C. A. M., Yariwake, J. H., Lancas, F. M., Wauters, J. N., Tits, M., & Angenot, L. (2004). A HPTLC densitometric determination of flavonoids from Passiflora alata, P-edulis, P-incarnata and P-caerulea and comparison with HPLC method. Phytochemical Analysis, 15 (4, JUL-AUG), 241-248. doi:10.1002/pca.778
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Goffin, E., da Cunha, A. P., Ziemons, E., Tits, M., Angenot, L., & Frederich, M. (November 2003). Quantification of tagitinin C in Tithonia diversifolia by reversed-phase high-performance liquid chromatography. Phytochemical Analysis, 14 (6), 378-80. doi:10.1002/pca.732
Peer Reviewed verified by ORBi

Frederich, M., Bentires-Alj, M., Tits, M., Angenot, L., Greimers, R., Gielen, J., Bours, V., & Merville, M.-P. (March 2003). Isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis, induces cell cycle arrest and apoptosis in human colon cancer cells. Journal of Pharmacology and Experimental Therapeutics, 304 (3), 1103-1110. doi:10.1124/jpet.102.044867
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Frederich, M., Bentires-Ali, M., Tits, M., Angenot, L., Heinen, E., & De Pauw-Gillet, M.-C. (March 2003). Apoptosis induction in human cancer cells by sungucine from Strychnos icaja root. Naunyn-Schmiedeberg's Archives of Pharmacology, 367 (3), 260-265. doi:10.1007/s00210-003-0691-x
Peer Reviewed verified by ORBi

Philippe, G., Angenot, L., De Mol, P., Goffin, E., Tits, M., & Frederich, M. (February 2003). In vitro screening of Strychnos species for antiplasmodial activity. Poster session presented at 27th Landelijk Overleg Farmacognosie (LOF) Symposium, Antwerpen, Belgium.

Philippe, G., De Mol, P., Zeches-Hanrot, M., Nuzillard, J. M., Tits, M., Angenot, L., & Frederich, M. (February 2003). Indolomonoterpenic alkaloids from Strychnos icaja roots. Phytochemistry, 62 (4), 623-629. doi:10.1016/S0031-9422(02)00612-X
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (2003). Indole alkaloids from Strychnos species and their antiplasmodial and cytotoxic activities. Chemistry of Natural Compounds, 39 (6, NOV-DEC), 513-519. doi:10.1023/B:CONC.0000018100.67335.b5

Garbacki, N., Tits, M., & Damas, J. (2003). Anti-inflammatory effect of natural proanthocyanidins: pharmacological evaluation on in vivo models. Pflügers Archiv: European Journal of Physiology, 446, 5.
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Frederich, M., Philippe, G., Tits, M., & Angenot, L. (30 October 2002). Strychnohexamine from Strychnos icaja, the first naturally occurring indolomonoterpenic trimeric alkaloid. Poster session presented at First International Pharmaceutical Congress, Tbilisi, Georgia.

Angenot, L., Garbacki, N., Damas, J., Bassleer, C., Frederich, M., & Tits, M. (29 October 2002). Effects of prodelphinidins isolated from Ribes nigrum leaves on chondrocyte metabolism and COX activity. Poster session presented at First International Pharmaceutical Congress, Tbilisi, Georgia.

Frederich, M., Jacquier, M. J., Thepenier, P., De Mol, P., Tits, M., Philippe, G., Delaude, C., Angenot, L., & Zeches-Hanrot, M. (October 2002). Antiplasmodial activity of alkaloids from various Strychnos species. Journal of Natural Products, 65 (10), 1381-1386. doi:10.1021/np020070e
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Frederich, M., Philippe, G., Prost, E., Nuzillard, J.-M., Zèches-Hanrot, M., Tits, M., & Angenot, L. (September 2002). Strychnohexamine from Strychnos icaja; the first naturally occurring indolomonoterpenoid trimeric alkaloid. Poster session presented at 2èmes Journées Internationales de l'AFERP, Athènes, Greece.

Lansiaux, A., Bailly, C., Houssier, C., Colson, P., De Pauw-Gillet, M.-C., Frederich, M., Tits, M., & Angenot, L. (July 2002). Apoptosis of HL-60 leukemia cells induced by the bisindole alkaloids sungucine and isosungucine from Strychnos icaja. Planta Medica, 68 (7), 591-595. doi:10.1055/s-2002-32889
Peer Reviewed verified by ORBi

Goffin, E., Ziemons, E., De Mol, P., de Madureira, M. D. C., Martins, A. P., da Cunha, A. P., Philippe, G., Tits, M., Angenot, L., & Frederich, M. (June 2002). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its main active constituent: tagitinin C. Planta Medica, 68 (6), 543-5. doi:10.1055/s-2002-32552
Peer Reviewed verified by ORBi

Garbacki, N., Angenot, L., Bassleer, C., Damas, J., & Tits, M. (June 2002). Effects of prodelphinidins isolated from Ribes nigrum on chondrocyte metabolism and COX activity. Naunyn-Schmiedeberg's Archives of Pharmacology, 365 (6), 434-441. doi:10.1007/s00210-002-0553-y
Peer Reviewed verified by ORBi

Philippe, G., Prost, E., Nuzillard, J. M., Zeches-Hanrot, M., Tits, M., Angenot, L., & Frederich, M. (29 April 2002). Strychnohexamine from Strychnos icaja, a naturally occurring trimeric indolomonoterpenic alkaloid. Tetrahedron Letters, 43 (18), 3387-3390. doi:10.1016/S0040-4039(02)00476-8
Peer Reviewed verified by ORBi

Sahpaz, S., Garbacki, N., Tits, M., & Bailleul, F. (March 2002). Isolation and pharmacological activity of phenylpropanoid esters from Marrubium vulgare. Journal of Ethnopharmacology, 79 (3), 389-392. doi:10.1016/S0378-8741(01)00415-9
Peer Reviewed verified by ORBi

Devia, B., Llabres, G., Wouters, J., Dupont, L., Escribano-Bailon, M. T., de Pascual-Teresa, S., Angenot, L., & Tits, M. (2002). New 3-deoxyanthocyanidins from leaves of Arrabidaea chica. Phytochemical Analysis, 13 (2, Mar-Apr), 114-120. doi:10.1002/pca.632
Peer Reviewed verified by ORBi

Goffin, E., Garbacki, N., Damas, J., Tits, M., Angenot, L., & Frederich, M. (2002). Tagitinin C from Tithonia diversifolia : anti-inflammatory activity and high performance liquid chromatogaphic quantification. Poster session presented at 50th Annual Congress of the Society for Medicinal Plant Research, Barcelona, Spain.

Garbacki, N., Tits, M., Angenot, L., & Damas, J. (2002). In vivo investigation of the anti-inflammatory activity of proanthocyanidins from Ribes nigrum leaves. Poster session presented at 50th Annual Congress of the Society for Medicinal Plant Research, Barcelona, Spain.

Penelle, J., Christen, P., Molgo, J., Tits, M., Brandt, V., Frederich, M., & Angenot, L. (October 2001). 5',6'-Dehydroguiachrysine and 5',6'-Dehydroguiaflavine, Two Curarizing Quaternary Indole Alkaloids from the Stem Bark of Strychnos Guianensis. Phytochemistry, 58 (4), 619-26. doi:10.1016/S0031-9422(01)00255-2
Peer Reviewed verified by ORBi

Goffin, E., Frederich, M., Philippe, G., Ziemons, E., De Mol, P., Proença da Cunha, A., Tits, M., & Angenot, L. (September 2001). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its active constituent: tagitinin C. Poster session presented at Lead Compounds from Higher Plants, Lausanne, Switzerland.

Frederich, M., Tits, M., HAYETTE, M.-P., De Mol, P., & Angenot, L. (September 2001). Reversal of Chloroquine and Mefloquine Resistance in Plasmodium falciparum by two monoindole alkaloids; icajine and isoretuline. Poster session presented at Lead Compounds from Higher Plants, Lausanne, Switzerland.

Frederich, M., Hayette, M.-P., Tits, M., De Mol, P., & Angenot, L. (August 2001). Reversal of Chloroquine and Mefloquine Resistance in Plasmodium Falciparum by the Two Monoindole Alkaloids, Icajine and Isoretuline. Planta Medica, 67 (6), 523-7. doi:10.1055/s-2001-16476
Peer Reviewed verified by ORBi

Brandt, V., Tits, M., Penelle, J., Frederich, M., & Angenot, L. (July 2001). Main Glucosidase Conversion Products of the Gluco-Alkaloids Dolichantoside and Palicoside. Phytochemistry, 57 (5), 653-9. doi:10.1016/S0031-9422(01)00085-1
Peer Reviewed verified by ORBi

Frederich, M., De Pauw-Gillet, M.-C., Prosperi, C., Tits, M., Brandt, V., Penelle, J., Hayette, M.-P., De Mol, P., & Angenot, L. (January 2001). Strychnogucines a and B, Two New Antiplasmodial Bisindole Alkaloids from Strychnos Icaja. Journal of Natural Products, 64 (1), 12-16. doi:10.1021/np000285t
Peer Reviewed verified by ORBi

Garbacki, N., Gloaguen, V., Damas, J., Bodart, P., Tits, M., & Angenot, L. (2001). Anti-inflammatory effects of Centaurea cyanus (Asteraceae) flower-heads. Poster session presented at International Symposium of the Phytochemical Society of Europe, Lead Compounds from Higher Plants, Lausanne, Switzerland.

Sahpaz, S., Garbacki, N., Tits, M., & Bailleul, F. (2001). Polyphénols du Marrube (Marrubium vulgare L.) et évaluation de l'activité anti-inflammatoire sur Cox-1 et Cox-2. Poster session presented at XVe Journées Franco-Belges de Pharmacochimie, Namur, Belgium.

Frederich, M., Tits, M., Penelle, J., Prosperi, C., HAYETTE, M.-P., De Mol, P., & Angenot, L. (September 2000). Strychnogucines A and B, two new antiplasmodial bisindole alkaloids from Strychnos icaja. Poster session presented at Natural Products Research in the new Millenium and Ethnopharmacology 2000, Zurich, Switzerland.

Penelle, J., Tits, M., Christen, P., Molgo, J., Frederich, M., & Angenot, L. (September 2000). Contribution to the study of Strychnos guianensis : purification and structural determination of potentially curarizing quaternary alkaloids. Poster session presented at Natural Products Research in the New Millenium and Ethnopharmacology 2000, Zurich, Switzerland.

De Pauw-Gillet, M.-C., Frederich, M., Tits, M., & Angenot, L. (July 2000). Etude du mécanisme d’action d’alcaloides bisindoliques, isolés du Strychnos icaja, à potentialité anticancéreuse. Poster session presented at Journées internationales de Pharmacognosie, Liege, Belgium.

Penelle, J., Tits, M., Christen, P., Molgo, J., Brandt Viviane, Frederich, M., & Angenot, L. (July 2000). Contribution à l'étude du Strychnos guianensis : purification et détermination de structure d'alcaloïdes quaternaires potentiellement curarisants. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Tits, M., de Leval Xavier, Dierckxsens, Y., Garbacki, N., Brandt Viviane, Penelle, J., Frederich, M., Delarge Jacques, & Angenot, L. (July 2000). Antiinflammatory and chonroprotective activity of prodelphinidins isolated from Ribes nigrum leaves. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Cristino, A., Tits, M., Penelle, J., Frederich, M., Brandt Viviane, & Angenot, L. (July 2000). Nouvelle méthode d'extraction et d'isolement de l'isostrychnopentamine à partir des feuilles de Strychnos usambarensis. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Brandt, V., Tits, M., Penelle, J., Frederich, M., & Angenot, L. (July 2000). Palicoside: précurseur naturel de l'akagérine. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Penelle, J., Tits, M., Christen, P., Molgo, J., Brandt, V., Frederich, M., & Angenot, L. (April 2000). Quaternary Indole Alkaloids from the Stem Bark of Strychnos Guianensis. Phytochemistry, 53 (8), 1057-66. doi:10.1016/S0031-9422(00)00033-9
Peer Reviewed verified by ORBi

Garbacki, N., Gloaguen, V., Damas, J., Hoffmann, L., Tits, M., & Angenot, L. (April 2000). Inhibition of Croton Oil-Induced Oedema in Mice Ear Skin by Capsular Polysaccharides from Cyanobacteria. Naunyn-Schmiedeberg's Archives of Pharmacology, 361 (4), 460-4. doi:10.1007/s002109900206
Peer Reviewed verified by ORBi

Frederich, M., De Pauw-Gillet, M.-C., Llabres, G., Tits, M., Hayette, M.-P., Brandt, V., Penelle, J., De Mol, P., & Angenot, L. (April 2000). New Antimalarial and Cytotoxic Sungucine Derivatives from Strychnos Icaja Roots. Planta Medica, 66 (3), 262-9. doi:10.1055/s-2000-8559
Peer Reviewed verified by ORBi

Tits, M., de Leval, X., Diercksens, Y., Garbacki, N., Brandt, V., Penelle, J., Frederich, M., Delarge, J., & Angenot, L. (2000). Anti-inflammatory and chondroprotective activity of prodelphinidins isolated from Ribes nigrum leaves. Poster session presented at International Congress and 48th Annual Meeting of the Society for Medicinal Plant Research (GA), 6th International Congress on Ethnopharmacology of the International Society for Ethnopharmacology (ISE), Zürich, Switzerland.

Garbacki, N., de Leval, X., Tits, M., Crisan, G., Wéry, B., Dekairelle, C., Wauters, J.-N., Delarge, J., & Angenot, L. (2000). Evaluation de l'activité anti-inflammatoire sur COX-1 et COX-2 de l'actéoside et de plantes médicinales en contenant. Poster session presented at Journées Internationales de Pharmacognosie, Liège, Belgium.

Brandt, V., Geerlings, A., Tits, M., Delaude, C., van der Hejden, R., Verpoorte, R., & Angenot, L. (2000). New strictosidine beta-glucosidase from Strychnos mellodora. Plant Physiology and Biochemistry, 38 (3), 187-192. doi:10.1016/S0981-9428(00)00738-5
Peer Reviewed verified by ORBi

Garbacki, N., Gloaguen, V., Damas, J., Bodart, P., Tits, M., & Angenot, L. (15 December 1999). Anti-Inflammatory and Immunological Effects of Centaurea Cyanus Flower-Heads. Journal of Ethnopharmacology, 68 (1-3), 235-41. doi:10.1016/S0378-8741(99)00112-9
Peer Reviewed verified by ORBi

Frederich, M., Hayette, M.-P., Tits, M., De Mol, P., & Angenot, L. (September 1999). In Vitro Activities of Strychnos Alkaloids and Extracts against Plasmodium Falciparum. Antimicrobial Agents and Chemotherapy, 43 (9), 2328-31. doi:10.1128/aac.43.9.2328
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., Hayette, M.-P., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (July 1999). 10'-hydroxyusambarensine, a new antimalarial bisindole alkaloid from the roots of Strychnos usambarensis. Poster session presented at 2000 Years of Natural Products Research - Past, Present and Future, Amsterdam, Netherlands.

Brandt, V., Geerlings, A., Tits, M., Penelle, J., Frederich, M., van der Heijden, R., Verpoorte, R., & Angenot, L. (July 1999). Kinetic properties of strictosidine glucosidase from Catharanthus roseus and on the new glucosidase from Strychnos mellodora in presence of strictosidine, dolichantoside and palicoside. Poster session presented at 2000 years of Natural Products Research - Past, Present and Future, Amsterdam, Netherlands.

Penelle, J., Tits, M., Christen, P., Frederich, M., & Angenot, L. (July 1999). Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis. Poster session presented at 2000 Years of Natural Products Research - Past, Present and Future, Amsterdam, Netherlands.

Penelle, J., Tits, M., Christen, P., Brandt, V., Frederich, M., & Angenot, L. (June 1999). Guiaflavine, a New Bisindole Quaternary Alkaloid from the Stem Bark of Strychnos Guianensis. Journal of Natural Products, 62 (6), 898-900. doi:10.1021/np9804738
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., HAYETTE, M.-P., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (May 1999). Isolement, détermination de structure et activité antimalarique de la 10'-hydroxyusambarensine: un nouvel alcaloïde bisindolique provenant des racines du Strychnos usambarensis. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Devia, B., Tits, M., Llabres, G., Wauters, J.-N., & Angenot, L. (May 1999). Isolement et confirmation spectroscopique de la structure de la carajurine, pigment rouge provenant des feuilles d'Arrabidaea chica. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Frederich, M., Tits, M., HAYETTE, M.-P., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (May 1999). Isolation, structure determination and antimalarial activity of 10'hydroxyusambarensine: a new bisindole alkaloid from the roots of Strychnos usambarensis. Paper presented at 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Penelle, J., Tits, M., Christen, P., Frederich, M., & Angenot, L. (May 1999). Guiaflavine, un nouvel alcaloïde quaternaire bisindolique isolé à partir de l'écorce de tige du Strychnos guianensis. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Penelle, J., Tits, M., Christen, P., Frederich, M., & Angenot, L. (May 1999). Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis. Paper presented at 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Brandt, V., Tits, M., Geerlings, A., Frederich, M., Penelle, J., Delaude, C., Verpoorte, R., & Angenot, L. (May 1999). Quatre alcaloïdes à noyau bèta-carboline isolés des écorces de tronc du Strychnos mellodora. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Brandt, V., Tits, M., Geerlings, A., Frederich, M., Penelle, J., Delaude, C., Verpoorte, R., & Angenot, L. (May 1999). Beta-Carboline Glucoalkaloids from Strychnos mellodora. Paper presented at 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Frederich, M., Tits, M., Hayette, M.-P., Brandt, V., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (April 1999). 10'-Hydroxyusambarensine, a New Antimalarial Bisindole Alkaloid from the Roots of Strychnos Usambarensis. Journal of Natural Products, 62 (4), 619-21. doi:10.1021/np980375m
Peer Reviewed verified by ORBi

Frederich, M., HAYETTE, M.-P., De Pauw-Gillet, M.-C., Tits, M., Angenot, L., & De Mol, P. (1999). In vitro activity of african Strychnos alkaloids against chloroquine resistant plasmodium falciparum. Poster session presented at 39th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), ASM’s Annual meeting in infectious diseases, San Fransisco, United States.

Garbacki, N., Gloaguen, V., Damas, J., Hoffmann, L., Tits, M., & Angenot, L. (1999). Anti-inflammatory properties of capsular polymers from blue-green algae. Paper presented at 8th International Conference on Applied Algology, Montecatini, Italy.

Garbacki, N., Gloaguen, V., Damas, J., Hoffmann, L., Tits, M., & Angenot, L. (1999). Propriétés anti-inflammatoires de polysaccharides capsulaires extraits de souches d'algues bleues. Poster session presented at 13ème Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Dassonneville, L., Wattez, N., Mahieu, C., Colson, P., Houssier, C., Frederich, M., Tits, M., Angenot, L., & Bailly, C. (1999). The plant alkaloid usambarensine intercalates into DNA and induces apoptosis in human HL60 leukemia cells. Anticancer Research, 19 (6B), 5245-5250.
Peer Reviewed verified by ORBi

Brandt, V., Tits, M., Geerlings, A., Frederich, M., Penelle, J., Delaude, C., Verpoorte, R., & Angenot, L. (1999). beta-carboline glucoalkaloids from Strychnos mellodora. Phytochemistry, 51 (8), 1171-1176. doi:10.1016/S0031-9422(99)00129-6
Peer Reviewed verified by ORBi

Biala, R. G., Tits, M., Penelle, J., Frederich, M., Brandt, V., Prosperi, C., Llabres, G., & Angenot, L. (23 January 1998). Strychnochrysine, a New Bisindole Alkaloid from the Roots of Strychnos Nux-Vomica. Journal of Natural Products, 61 (1), 139-41. doi:10.1021/np9703454
Peer Reviewed verified by ORBi

Frederich, M., Quetin-Leclercq, J., Biala, R. G., Brandt, V., Penelle, J., Tits, M., & Angenot, L. (1998). 3 ',4 ',5 ',6 ' tetradehydrolongicaudatine Y, an anhydronium base from Strychnos usambarensis. Phytochemistry, 48 (7), 1263-1266. doi:10.1016/S0031-9422(97)00944-8
Peer Reviewed verified by ORBi

Bonjean, K., De Pauw-Gillet, M.-C., Defresne, M.-P., Colson, P., Houssier, C., Dassonneville, L., Bailly, C., Greimers, R., Wright, C., Quetin-Leclercq, J., Tits, M., & Angenot, L. (1998). The DNA intercalating alkaloid cryptolepine interferes with topoisomerase II and inhibits primarily DNA synthesis in B16 melanoma cells. Biochemistry, 37 (15), 5136-46. doi:10.1021/bi972927q
Peer Reviewed verified by ORBi

Bonjean, K., De Pauw-Gillet, M.-C., Defresne, M.-P., Colson, P., Houssier, C., Dassonneville, L., Bailly, C., GREIMERS, R., Wright, C., Quetin-Leclercq, J., Tits, M., & Angenot, L. (January 1998). Cryptolepine is a potent DNA intercalating agent which inhibits selectively DNA synthesis in B16 melanoma cells cultured in vitro. Poster session presented at International Symposium Antitumour Products from higher plants, Paris, France.

Frederich, M., Tits, M., & Angenot, L. (1998). Qualitative and quantitative evaluation of bisindole usambarane alkaloids in Strychnos usambarensis roots by high performance liquid chromatography diode-array. Phytochemical Analysis, 9 (2), 63-66. doi:10.1002/(SICI)1099-1565(199803/04)9:2<63::AID-PCA388>3.0.CO;2-9
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (April 1997). Qualitative and quantitative evaluation of bisindole usambarane alkaloids in Strychnos usambarensis roots by HPLC. Paper presented at 7th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Penelle, J., Scuvée-Moreau, J., Tits, M., Dresse, A., & Angenot, L. (April 1997). A pharmacological comparison of Strychnos guianensis and curare compounds on the neuromuscular transmission. Paper presented at 7th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Bonjean, K., De Pauw-Gillet, M.-C., Defresne, M.-P., Colson, P., Houssier, C., Dassonneville, L., Bailly, C., GREIMERS, R., Wright, C., Quetin-Leclercq, J., Tits, M., & Angenot, L. (1997). Cryptolepine is a potent DNA intercalating agent which inhibits selectively DNA synthesis in B16 melanoma cells cultured in vitro. Poster session presented at New Anticancer Agents, Athène, Greece.

Brandt, V., Tits, M., & Angenot, L. (May 1996). Glucoindole alkaloids from stem bark of Strychnos mellodora. Paper presented at 6e Forum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Brandt, V., Tits, M., & Angenot, L. (February 1996). Glucoindole alkaloids from stem bark of Strychnos mellodora. Poster session presented at 6th symposium SLW - discussion group "Secondary metabolism in plant and plantcell, Leiden, Netherlands.

Tits, M., Brandt, V., Wauters, J.-N., Delaude, C., Llabres, G., & Angenot, L. (February 1996). Glucoindole Alkaloids from Stem Bark of Strychnos Mellodora. Planta Medica, 62 (1), 73-4. doi:10.1055/s-2006-957807
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Gadi Biala, R., Tits, M., Wauters, J.-N., & Angenot, L. (1996). A new HPLC method for the assay of alkaloids in Strychnos nux-vomica and Strychnos ignatii. Fitoterapia, 67 (2), 163-165.
Peer Reviewed verified by ORBi

Poukens-Renwart, P., Tits, M., & Angenot, L. (1996). Quantitative Densitometric Evaluation of Harpagoside in the Secondary Roots of Harpagophytum procumbens D.C. Journal of Planar Chromatography, 9 (May/June), 199-202.
Peer reviewed

Franchimont, P., Bassleer, C., Angenot, L., & Tits, M. (07 July 1994). Utilisation de prodelphinidines pour le traitement de l'arthrose.

Bodart, P., Tits, M., & Angenot, L. (May 1994). Activité antiinflammatoire du mucilage de bleuet. Poster session presented at 8èmes Journées franco-Belges de Pharmacochimie, Liège, Belgium.

Bodart, P., Goldsztajn, V., Tits, M., & Angenot, L. (March 1994). Antiinflammatory activity of centaurea cyanus flowers. Poster session presented at 5e forum des sciences pharmaceutiques, Blankenberge, Belgium.

Quarré, M.-N., Tits, M., Wauters, J.-N., & Angenot, L. (March 1994). On the occurrence of (iso-)dolichantoside in Strychnos mellodora. Poster session presented at 5e Foreum des Sciences Pharmaceutiques, Blankenberge, Belgium.

Bodart, P., Damas, J., Goldsztajn, V., Tits, M., & Angenot, L. (February 1994). Antiinflammatory activity of Centaurea cyanus flowers. Journal de Pharmacie de Belgique, 59 (1), 73.
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Wright, C., Allen, D., Cai, Y., Chen, Z., Phillipson, J., Kirby, G., Warhurst, D., Tits, M., & Angenot, L. (1994). Selective Antiprotozoal Activity of Some Strychnos Alkaloids. Phytotherapy Research, 8, 149-152. doi:10.1002/ptr.2650080306
Peer Reviewed verified by ORBi

Poukens-Renwart, P., Tits, M., & Angenot, L. (1993). Semi-Quantitative Salicin Analysis According the German Pharmacopoeia (DABX): Avoidance of Picein Interference. Planta Medica, 59 (Supplement Issue), 629-A630.
Peer Reviewed verified by ORBi

Poukens-Renwart, P., Tits, M., & Angenot, L. (1993). Densitometric Determination of Salicin in Willow Stem Bark. Journal of Planar Chromatography, 6 (november-december), 434-437.
Peer reviewed

Tits, M., Poukens, P., Angenot, L., & Dierckxsens, D. (1993). Thin-Layer chromatographic analysis of proanthocyanidins from Ribes nigrum leaves. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12), 1097-1100. doi:10.1016/0731-7085(91)80128-V
Peer Reviewed verified by ORBi

Tits, M., & Angenot, L. (03 September 1992). Utilisation en thérapeutique de pycnogenols pour la préparation de médicaments à activité anti-inflammatoire.

Poukens-Renwart, P., Tits, M., Wauters, J.-N., & Angenot, L. (September 1992). Densitometric evaluation of spiraeoside after derivatization in flowers of Filipendula ulmaria (L.) Maxim. Poster session presented at 4th International Congress on Phytotherapy, Munich, Germany.

Tits, M., Poukens, P., & Angenot, L. (May 1992). Proanthocyanidins from Ribes nigrum leaves. Poster session presented at 4th International Symposium on Drug Analysis, Liège, Belgium.

Poukens-Renwart, P., Tits, M., Wauters, J.-N., & Angenot, L. (May 1992). Densitometric evaluation of fraxin in leaves of Fraxinus excelsior. Poster session presented at 4th International symposium on Drug Analysis, Liège, Belgium.

Tits, M., Angenot, L., Warin, R., & Dierckxsens, Y. (May 1992). Proanthocyanidins from Ribes nigrum 1 Isolation and structure determination. Poster session presented at 4th International Symposium on Drug Analysis, Liège, Belgium.

Poukens-Renwart, P., Tits, M., Wauters, J.-N., & Angenot, L. (1992). Densitometric Evaluation of Spiraeoside after Derivatization in Flowers of Filipendula Ulmaria (L.) Maxim. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12, Oct-Dec), 1085-8. doi:10.1016/0731-7085(91)80125-S
Peer Reviewed verified by ORBi

Poukens-Renwart, P., Tits, M., Wauters, J.-N., & Angenot, L. (1992). Densitometric Evaluation of fraxin in leaves of Fraxinus excelsior. Journal de Pharmacie de Belgique, 47 (3), 241.
Peer Reviewed verified by ORBi

Poukens-Renwart, P., Tits, M., Wauters, J.-N., & Angenot, L. (1992). Reversed-Phase Hptlc Densitometric Evaluation of Fraxin in Fraxinus Excelsior Leaves. Journal of Pharmaceutical and Biomedical Analysis, 10 (10-12, Oct-Dec), 1089-91. doi:10.1016/0731-7085(91)80126-T
Peer Reviewed verified by ORBi

Tits, M., Angenot, L., Warin, R., & Dierckxsens, Y. (1992). Proanthocyanidins from Ribes nigrum leaves - Isolation and structure determination. In Bulletin de Liaison Groupe Polyphenols (pp. 178-181).
Peer reviewed

Tits, M., Poukens, P., & Angenot, L. (1992). Proanthocyanidins from Ribes nigrum leaves : TLC Analysis. In Bulletin de Liaison - Groupe Polyphenols (pp. 182-185).
Peer reviewed

Poukens-Renwart, P., Tits, M., Wauters, J.-N., & Angenot, L. (1992). Densitometric evaluation of spiraeoside in Filipendula ulmaria flowers after derivatization. Poster session presented at 4th International Symposium on Drug Analysis, Liège, Belgium.

Tits, M., Angenot, L., Poukens, P., Warin, R., & Dierckxsens, D. (1992). Prodelphinidins from Ribes nigrum. Phytochemistry, 31 (3), 971-973. doi:10.1016/0031-9422(92)80050-O
Peer Reviewed verified by ORBi

Quetin-Leclercq, J., Tits, M., Angenot, L., & Bisset, N. G. (October 1991). Alkaloids of Strychnos Usambarensis Stem Bark. Planta Medica, 57 (5), 501. doi:10.1055/s-2006-960185
Peer Reviewed verified by ORBi

Tits, M., Angenot, L., Damas, J., Dierckxsens, Y., & Poukens, P. (1991). Antiinflammatory Prodelphinidins from Black Currant (Ribes nigrum) Leaves. Planta Medica, 57 (Supplement issue 2), 134.
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Tits, M., Damas, J., Quetin-Leclercq, J., & Angenot, L. (1991). From ethnobotanical uses of Strychnos henningsii to antiinflammatories, analgesics and antispasmodics. Journal of Ethnopharmacology, 34, 261-267. doi:10.1016/0378-8741(91)90045-F
Peer Reviewed verified by ORBi

Tits, M., & Angenot, L. (September 1990). Synthesis and antimitotic effects of isoretulinal, a main alkaloid isolated from Strychnos variabilis. Poster session presented at 4mes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Tits, M., Poukens, P., & Angenot, L. (July 1990). Proanthocyanidins from Ribes nigrum 2. TLC Analysis. Poster session presented at XVIes Journées Internationales du Groupe Polyphénols, Lisboa ( Lisbonne), Portugal.

Tits, M., Angenot, L., Warin, R., & Dierckxsens, Y. (July 1990). Proanthocyanidins from Ribes nigrum leaves 1. Isolation and structure determination. Poster session presented at XVIth International conference of the "Groupe Polyphénols", Lisbon ( Lisbonne), Portugal.

Angenot, L., Damas, J., & Tits, M. (June 1990). From ethnobotanical uses of Strychnos henningsii to antinflammatories,analgesics and antispasmodics. Poster session presented at First International Congress on Ethnopharmacology, Strasbourg, France.

Tits, M., Bassleer, R., & Angenot, L. (1990). Synthesis and antimitotic effects of isoretulinal, a main alkaloid isolated from Strychnos variabilis. Journal de Pharmacie de Belgique, 45 (6), 393.
Peer Reviewed verified by ORBi

Angenot, L., Damas, J., & Tits, M. (15 June 1989). Utilisation de composés de la série de la rétuline et de l'isorétuline à titre de composés à activité pharmaceutique, en particulier de médicaments analgésiques, antispasmodiques et antiinflammatoires.

Tavernier, D., Zhang, W., Angenot, L., Tits, M., & Leclercq, J. (1987). The structure of isostrychnopentamine, a bisindole monoterpene alkaloid from Strychnos usambarensis. Phytochemistry, 26 (2), 557-560. doi:10.1016/S0031-9422(00)81453-3
Peer Reviewed verified by ORBi

Angenot, L., Tavernier, D., Tits, M., & Zhang, W. (October 1986). The structure of isostrychnopentamine A, a new bisindole monoterpene alkaloid with antimitotic properties. Poster session presented at 13de symposium farmacognosie en natuurstofchemie, Leuven, Belgium.

Bassleer, R., Clermont, D., Marnette, J. M., Caprasse, M., Tits, M., & Angenot, L. (1985). Effets de la dihydroflavopéreirine et de la sempervirine (alacaloïdes dérivés de la beta-carboline) sur des cellules cancéreuses en culture. Annales Pharmaceutiques Françaises, 43 (1), 83-88.
Peer Reviewed verified by ORBi

Tits, M., Tavernier, D., & Angenot, L. (1985). Strychnozairine, an indole alkaloid from Strychnos variabilis. Phytochemistry, 34 (1), 205-207. doi:10.1016/S0031-9422(00)80847-X
Peer Reviewed verified by ORBi

Tits, M., Tavernier, D., & Angenot, L. (July 1984). The structure of strychnozairine, a new indole alkaloid from Strychnos variabilis. Poster session presented at 32nd Annual Congress for Medicinal Plant research, Antwerp, Belgium.

Tits, M., Desaive, C., Marnette, J. M., Bassleer, R., & Angenot, L. (1984). Antimitotic activity of strychnopentamine, a bisindolic alkaloid. Journal of Ethnopharmacology, 12, 287-292. doi:10.1016/0378-8741(84)90058-8
Peer Reviewed verified by ORBi

Dehaussy, H., Tits, M., & Angenot, L. (September 1983). La guattegaumerine, nouvel alcaloide bisbenzylisoquinoleinique de Guatteria gaumeri. Planta Medica, 49 (9), 25-7. doi:10.1055/s-2007-969803
Peer Reviewed verified by ORBi

Tits, M., Angenot, L., & Tavernier, D. (1983). Didéhydro-16,17 isostrychnobiline, nouvel alcaloÏde bisindolinique asymétrique du Strychnos variabilis. Journal de Pharmacie de Belgique, 38 (5), 241-245.
Peer Reviewed verified by ORBi

Tits, M., Angenot, L., & Tavernier, D. (1983). 12'-Hydroxystrychnobiline, nouvel alcaloïde bisindolinique du Strychnos variabilis. Journal of Natural Products, 46 (5), 638-645. doi:10.1021/np50029a008
Peer Reviewed verified by ORBi

Tits, M., Tavernier, D., & Angenot, L. (16 September 1982). Comparison of stereochemistry for strychnobiline and isostrychnobiline, the main alkaloids isolated from the roots of Strychnos variabilis. Poster session presented at 9e symposium voor Farmacognosie en Natuurstofchemie, Antwerpen, Belgium.

Coune, C., Tits, M., & Angenot, L. (1982). RMN C13 des alcaloïdes des Strychnos : les dérivés de l'usambarine, de la sarpagine et de la mavacurine. Journal de Pharmacie de Belgique, 37 (3), 189-194.
Peer Reviewed verified by ORBi

Tits, M., Franz, M., Tavernier, D., & Angenot, L. (August 1981). Les alcaloides quaternaires majoritaires du Strychnos variabilis du Zaire. Planta Medica, 42 (8), 371-4.
Peer Reviewed verified by ORBi

Angenot, L., & Tits, M. (March 1981). Isolement d'un Nouvel Alcaloide (O-Acetylretuline) et d'un Triterpenoide (Friedeline) à partir du Strychnos henningsii du Zaire. Planta Medica, 41 (3), 240-3. doi:10.1055/s-2007-971709
Peer Reviewed verified by ORBi

Angenot, L., Caprasse, M., Coune, C., & Tits, M. (1981). Se soigner par les plantes. Bruxelles, Belgium: Association des Consommateurs.

Tits, M., Angenot, L., & Tavernier, D. (1980). New indole aldehydic alkaloids of Strychnos variabilis. Tetrahedron Letters, 21, 2439-2442. doi:10.1016/S0040-4039(00)93170-8
Peer Reviewed verified by ORBi

Tits, M., Tavernier, D., & Angenot, L. (1980). Alcaloïdes indoliniques du Strychnos variabilis. Phytochemistry, 19 (7), 1531-1534. doi:10.1016/0031-9422(80)80211-1
Peer Reviewed verified by ORBi

Tits, M., & Angenot, L. (1980). Alcaloïdes des feuilles du Strychnos variabilis. Plantes Médicinales et Phytothérapie, 14 (4), 213-217.
Peer reviewed

Tits, M., Tavernier, D., & Angenot, L. (1979). La 12'-hydroxyisostrychnobiline, nouvel alcaloïde du Strychnos variabilis. Phytochemistry, 18, 515-516.
Peer Reviewed verified by ORBi

Tits, M., & Angenot, L. (1978). Nouveaux alcaloïdes bis-indoliques dans l'écorce des racines du Streychnos variabilis. Planta Medica, 34, 57-61.
Peer Reviewed verified by ORBi

Angenot, L., Coune, C., & Tits, M. (1978). Nouveaux alcaloïdes des feuilles de Strychnos usambarensis. Journal de Pharmacie de Belgique, 33 (1), 11-23.
Peer Reviewed verified by ORBi

Tavernier, D., Anteunis, M. J. O., Tits, M., & Angenot, L. (1978). The 1H NMR spectra of the Strychnos alkaloids Retuline and Isoretuline, and their N-deacetyl compounds. Bulletin de la Société Chimique de Belgique, 87 (8), 595-607.
Peer reviewed

Angenot, L., Coune, C., & Tits, M. (1978). Les alcaloïdes des fruits et des feuilles du Strychnos usambarensis. Journal de Pharmacie de Belgique, 33 (5), 284-286.
Peer Reviewed verified by ORBi

Angenot, L., Coune, C., Tits, M., & Yamada, K. (1978). Alkaloids from Strychnos usambarensis: revised structure for usambarine. Phytochemistry, 17 (9), 1687-1689. doi:10.1016/S0031-9422(00)94682-X
Peer Reviewed verified by ORBi

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