Profil

Frederich Michel

Département de pharmacie > Pharmacognosie

CIRM

See author's contact details
ORCID
0000-0002-0770-9990

Main Research Fields
Pharmacy, pharmacology & toxicology
Phytobiology (plant sciences, forestry, mycology...)
Chemistry
Biochemistry, biophysics & molecular biology
Food science
Main Keywords
Malaria; Strychnos; malaria; Plasmodium falciparum; antiplasmodial activity;
Main Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Centre Interfacultaire de Recherche du Médicament - CIRM
Food Science and Formulations
AgricultureIsLife, TERRA Teaching and Research Centre - TERRA
TERRA Teaching and Research Centre - TERRA
Main Co-authors
Angenot, Luc 
Tits, Monique 
Jansen, Olivia 
Ledoux, Allison 
De Mol, Patrick 

Publications (total 398)

The most downloaded
18817 downloads
Frederich, M. (20 January 2014). « Les plantes qui nous soignent : de la tradition à la médecine moderne ». Paper presented at Les grandes conférences de l'Université de Liège à Verviers. https://hdl.handle.net/2268/163401
The most cited
122 citations (SCOPUS)
Bero, J., Frederich, M., & Quetin-Leclercq, J. (2009). Antimalarial compounds isolated from plants used in traditional medicine. Journal of Pharmacy and Pharmacology, 61 (11), 1401-33. doi:10.1211/jpp.61.11.0001 https://hdl.handle.net/2268/28405

Degotte, G., Pirotte, B., Francotte, P., & Frederich, M. (In press). Potential of caffeic acid derivatives as antimalarial leads. Letters in Drug Design and Discovery.
Peer Reviewed verified by ORBi

Bonnet, O., Beniddir, M. A., Champy, P., Degotte, G., Coelho Cristino Mamede, L. C., Desdemoustier, P., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (13 July 2022). Identification of new alkaloids active against malaria by molecular networking based on in vitro antiplasmodial activities of 28 Strychnos species. Paper presented at Journées virtuelles de l'AFERP 2022 (Virtual days of AFERP 2022).

Degotte, G., Strharsky, T., Kos, J., Francotte, P., Frederich, M., & Jampilek, J. (July 2022). Antimalarial Activity of Novel Substituted N-Arylcinnamamides. Poster session presented at 3rd MMCS: Shaping Medicinal Chemistry for the New Decade, Roma, Italy.

Bonnet, O., Beniddir, M. A., Champy, P., Kagisha, V., Nyirimigabo, A., Hamann, C., Jgerenaia, G., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (2022). Exploration by molecular networking of Strychnos alkaloids reveals the unexpected occurrence of strychnine in seven Strychnos species. Toxicon. doi:10.1016/j.toxicon.2022.06.002
Peer Reviewed verified by ORBi

Jgerenaia, G., Sulakvelidze, M., Novikova, Z., Gogitidze, N., Mushkiashvili, N., Mulkijanyan, K., Frederich, M., & Mskhiladze, L. (2022). PHARMACOLOGICAL ASSESSMENT OF CONSTITUENTS OF SPECIES ALLIUM SAXATILE AND ALLIUM PONTICUM GROWING IN GEORGIA. EXPERIMENTAL & CLINICAL MEDICINE GEORGIA. doi:10.52340/jecm.2022.06.04
Editorial reviewed

Stankovic, M., Baptista, P., Carillo, P., Păltine, R., Ielciu, I.* , Hangan, D., Nicula, M., Pa, E., Angenot, L., Tits, M., Moca, A., Babotă, M., Frumuzachi, O., Tămaş, M., Crişan, G., & Frederich, M. (2022). Biological Activities of Some Isoquinoline Alkaloids from Fumaria schleicheri Soy. Will. Plants. doi:10.3390/plants11091202
Peer Reviewed verified by ORBi

Leka, K., Hamann, C., Desdemoustier, P., Frederich, M., Garigliany, M.-M., & Ledoux, A. (2022). In vitro antiviral activity against SARS-CoV-2 of common herbal medicinal extracts and their bioactive compounds. Phytotherapy Research. doi:10.1002/ptr.7463
Peer Reviewed verified by ORBi

Fall, F., Coelho Cristino Mamede, L. C., Schioppa, L., Ledoux, A., De Tullio, P., Michels, P., Frederich, M., & Quetin-Leclercq, J. (19 March 2022). Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery. Metabolomics, 18 (4), 20. doi:10.1007/s11306-022-01880-0
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Schoumacher, M., Cirillo, A., Fall, F., Bugli, C., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (02 February 2022). Exploration of untargeted metabolomic extraction methods of in vitro malaria samples by 1H NMR analysis - follow up. Poster session presented at CIRM Day, Liège, Belgium.

Hamann, C., Jansen, O., Desdemoustier, P., Marotte, A., Bonnet, O., Maquoi, E., & Frederich, M. (02 February 2022). Preliminary study of the phytochemical composition and biological activity of 5 varieties of hemp cultivated in Wallonia. Poster session presented at CIRMDay2022.

Bonnet, O., Derbré, S., Beniddir, M. A., Champy, P., Hamann, C., & Frederich, M. (02 February 2022). Dereplication of Strychnos species: NMR data and MixONat software as complementary tools to MS analyses. Poster session presented at 4th CIRM Day, Liège, Belgium.

Bonnet, O., Beniddir, M. A., Champy, P., Kagisha, V., Nyirimigabo, A., Hamann, C., Jgerenaia, G., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (02 February 2022). Chemometric study of Strychnos species by molecular networking: example of the occurrence of strychnine. Paper presented at 4th CIRM Day, Liège, Belgium.

Ledoux, A., Leka, K., Bonnet, O., Blanquer, A., Tiabou Tchinda, A., Mirowski, P., Figueiredo, P., Desmecht, D., Garigliany, M.-M., & Frederich, M. (10 January 2022). In vitro antiviral activity against SARS-CoV-2 of 28 Strychnos extracts. Phytotherapy Research, 1 (3). doi:10.1002/ptr.7394
Peer Reviewed verified by ORBi

Danthine, S., Aman, P., Jansen, O., Ducrey, A., Richel, A., Lognay, G., Maesen, P., Mutwale Kapepula, P., Mouithys-Mickalad, A., Franck, T., & Frederich, M. (2022). Prunella vulgaris L. seeds: a promising source of lipids, proteins, and original phenolic compounds presenting high antioxidant and anti-inflammatory activity. Biotechnologie, Agronomie, Société et Environnement, 26 (1), 1-15. doi:10.25518/1780-4507.19412
Peer Reviewed verified by ORBi

Taouba, H., Vitello, R., Lumb, J.-P., Seutin, V., Frederich, M., & Liégeois, J.-F. (19 November 2021). A NEW APPROACH FOR THE TREATMENT OF MALARIA THROUGH SK CHANNEL MODULATION ? Poster session presented at MedChem 2021, Liège, Belgium.

Degotte, G., Pirotte, B., Pendeville-Samain, H., Frederich, M., & Francotte, P. (19 November 2021). Pharmacomodulation of Ellagic Acid to Identify New Antimalarial Candidates. Poster session presented at MedChem 2021, Liège, Belgium.

Coelho Cristino Mamede, L. C., Schoumacher, M., Cirillo, A., Fall, F., Bugli, C., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (November 2021). Exploration of untargeted metabolomic extraction methods for in vitro malaria samples by 1H NMR analysis. Poster session presented at 14èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique, Aussois, France.

Degotte, G., Pirotte, B., Frederich, M., & Francotte, P. (2021). Polyhydroxybenzoic acid derivatives as potential new antimalarial agents. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft. doi:10.1002/ardp.202100190
Peer reviewed

Bonnet, O., Beniddir, M. A., Champy, P., Hamann, C., & Frederich, M. (15 July 2021). Chemoinformatics analyses of species of the Strychnos genus by molecular networking: investigation of strychnine. Poster session presented at Journées virtuelles de l'AFERP 2021.

Ledoux, A., Bériot, D., Coelho Cristino Mamede, L. C., Desdemoustier, P., Detroz, F., Jansen, O., Frederich, M., & Maquoi, E. (2021). Cytotoxicity of Poupartone B, an Alkyl Cyclohexenone Derivative from Poupartia borbonica, against Human Cancer Cell Lines. Planta Medica. doi:10.1055/a-1532-2384
Peer Reviewed verified by ORBi

Degotte, G., Pirotte, B., Pendeville-Samain, H., Duwez, L., Frederich, M., & Francotte, P. (28 May 2021). Gallic acid dimerization to open the way for new antimalarial drugs. Paper presented at One-Day FNRS Med Chem Meeting, Louvain-La-Neuve, Belgium.

Taouba, H., Vitello, R., Lumb, J.-P., Seutin, V., Frederich, M., & Liégeois, J.-F. (26 May 2021). Could Bis-THIQ compounds inhibit plasmodial growth through SK channel interaction ? Poster session presented at CIRM-day, LIEGE, Belgium.

Degotte, G., Pirotte, B., Pendeville-Samain, H., Duwez, L., Frederich, M., & Francotte, P. (26 May 2021). Gallic acid dimerization to open the way for new antimalarial drugs. Poster session presented at 3rd CIRMDay, Liège, Belgium.

Bonnet, O., Beniddir, M. A., Champy, P., Hamann, C., & Frederich, M. (26 May 2021). Exploration of Strychnos alkaloids: study of strychnine in trunk barks of Strychnos densiflora. Poster session presented at 3rd CIRM Day, Liège, Belgium.

Tomani, J. C. D., Bonnet, O., Nyirimigabo, A., Deschamps, W., Tchinda, A. T., Jansen, O., Ledoux, A., Mukazayire, M.-J., Vanhamme, L., Frederich, M., Muganga, R., & Souopgui, J. (10 May 2021). In Vitro Antiplasmodial and Cytotoxic Activities of Compounds from the Roots of Eriosema montanum Baker f. (Fabaceae). Molecules, 26 (9), 2795. doi:10.3390/molecules26092795
Peer Reviewed verified by ORBi

Kowa, T., Jansen, O., Ledoux, A., Coelho Cristino Mamede, L. C., Wabo, H., Tchinda Tiabou, A., Genta-Jouve, G., & Frederich, M. (2021). Bioassay-guided isolation of vilasinin–type limonoids and phenyl alkene from the leaves of Trichilia gilgiana and their antiplasmodial activities. Natural Product Research. doi:10.1080/14786419.2021.1920017
Peer Reviewed verified by ORBi

Degotte, G., Pirotte, B., Francotte, P., & Frederich, M. (2021). Overview of natural antiplasmodials from the last decade to inspire medicinal chemistry. Current Medicinal Chemistry. doi:10.2174/0929867328666210329112354
Peer Reviewed verified by ORBi

Toukam, P. D., Kom, C. W., Tchamgoué, A. D., Doupno, E. A. K., Lame, Y., Yamthé, L. R. T., Kopa Kowa, T., Tchinda, A. T., Frederich, M., Mbafor, J. T., & De Théodore Atchadé, A. (2021). A new isoquinoline and ceramide from the stem barks of Discoglypremna caloneura (Pax) Prain (Euphorbiaceae) with antiproteinase and cytotoxic activities. Natural Product Research, 1-9. doi:10.1080/14786419.2021.1890073
Peer Reviewed verified by ORBi

Nea, F., Bitchi, B. M., Genva, M., Ledoux, A., Tchinda Tiabou, A., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (15 January 2021). Phytochemical investigation and biological activities from Lantana rhodesiensis Moldenke. Poster session presented at Les Journées Jeunes Chercheurs Condorcet - J2C2.

Kagisha, V., Marini Djang'Eing'A, R., Muganga, R., Bonnet, O., Tchinda, A. T., Jansen, O., Tomani, J. C., Njakarinala, R., Ledoux, A., Nyirimigabo, A., & Frederich, M. (2021). Pentas longiflora Oliv. (Rubiaceae), a plant used in the treatment of Pityriasis Versicolor in Rwanda: Chemical composition and standardization of leaves and roots. Fitoterapia, 153, 104974. doi:10.1016/j.fitote.2021.104974
Peer Reviewed verified by ORBi

Kapepula, P. M., Mungitshi, P. M., Tshitenge, D. T., Franck, T., Ngoyi, D. M., Kalenda, P. D. T., Tits, M., Frederich, M., Ngombe, N. K., & Mouithys-Mickalad, A. (2021). Microscopic Characteristics , Chromatographic Profiles and Inhibition of Peroxidase Activity of the Leaves of Manihot esculenta and Manihot glaziovii , Consumed as Traditional Vegetables. Journal of Biosciences and Medicines, 9, 59--73. doi:10.4236/jbm.2021.99006
Peer reviewed

Ma'mag, L. K., Zintchem, A. A. A., Théodora, K. K., Théodore, A. A. D., lauve, T. Y., Frederich, M., Bikobo, D. S. N., & Pegnyemb, D. E. (2021). Antiplasmodial and antileishmanial inhibitory activity of triterpenes and steroidal alkaloid from the leaves of Funtumia elastica (Preuss) Stapf (Apocynaceae). Fitoterapia, 104869. doi:10.1016/j.fitote.2021.104869
Peer Reviewed verified by ORBi

Nea, F., Bitchi, M. B., Genva, M., Ledoux, A., Tchinda Tiabou, A., Damblon, C., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (2021). Phytochemical investigation and biological activities of Lantana rhodesiensis. Molecules, 26 (4), 846. doi:10.3390/molecules26040846
Peer Reviewed verified by ORBi

Kagisha, V., Frederich, M., muganga, R., Marini Djang'Eing'A, R., Maeva, J., Uwambajimana, C., & Umumararungu, A. (09 December 2020). FROM MEDICINAL PLANT TO THE IMPROVED HERBAL MEDICINE. Poster session presented at Fete de la Science, Huye, Rwanda.

Kagisha, V., Muganga, R., Marini Djang'Eing'A, R., & Frederich, M. (27 September 2020). HPLC-UV method for standardization of Neorautanenia mitis, an African plant used in an anti-scabies ointment. Paper presented at Michel Frederich, Kigali, Rwanda.

Saive, M.* , Genva, M.* , Istasse, T., Frederich, M., Maes, C., & Fauconnier, M.-L. (18 September 2020). Identification of a proanthocyanidin from Litchi chinensis Sonn. root with anti-tyrosinase and antioxidant activity. Biomolecules, 10 (9), 1347. doi:10.3390/biom10091347
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Salabao, L., Frederich, M., Lepoint, G., Verheye, M., & Schon, I. (August 2020). How the Genus Eusirus amphipods evolved and speciated in the Antarctic. Paper presented at SCAR Online Conference 2020.

Kagisha, V., Frederich, M., Ledoux, A., Jansen, O., NYIRIMIGABO, A., MUGANGA, R., & Marini Djang'Eing'A, R. (10 June 2020). HPLC-UV Method for Standardization of Neorautanenia mitis, an African Plant Used in an Anti-Scabies Ointment. Revista Brasileira de Farmacognosia, 30 (4), 582-587. doi:10.1007/s43450-020-00070-0
Peer reviewed

Ledoux, A., Coelho Cristino Mamede, L. C., Palazzo, C., Furst, T., Jansen, O., De Tullio, P., Kagisha, V., Pendeville-Samain, H., Fillet, M., Piel, G., & Frederich, M. (18 May 2020). Heparin-Coated Liposomes Improve Antiplasmodial Activity and Reduce the Toxicity of Poupartone B. Planta Medica International Open, 7 (e), 73–80. doi:10.1055/a-1158-0569
Peer Reviewed verified by ORBi

Degotte, G., Pirotte, B., Frederich, M., & Francotte, P. (20 February 2020). Pharmacomodulation of natural compounds: medicinal chemistry in antimalarial purposes. Poster session presented at ChemCys 2020, Blankenberg, Belgium.

Catteau, L., Schioppa, L., Beaufay, C., Girardi, C., Hérent, M.-F., Frederich, M., & Quetin-Leclercq, J. (2020). Antiprotozoal activities of Triterpenic Acids and Ester Derivatives Isolated from the Leaves of Vitellaria paradoxa. Planta Medica. doi:10.1055/a-1286-1879
Peer Reviewed verified by ORBi

Mavungu Landu, D. J., Marini Djang'Eing'A, R., Hubert, P., Frederich, M., Michel, B., Gretry, L., Messina Ndzomo, J. P., Bruyère, O., Reginster, J.-Y., & Manzambi Kuwekita, J. (2020). Les déterminants de l’accès à des médicaments antipaludiques de qualité en territoires périurbains africains : résultats d’une enquête menée à Kinshasa (Congo). Journal d’Épidémiologie et de Santé Publique, 21, 85-100.
Peer reviewed

Mavungu Landu, D. J., Frederich, M., Manzambi Kuwekita, J., Bongo-Pasi Nswe, C., Mbinze Kindenge, J., Liégeois, S., Kalenda Tshilombo, N., Mineze Kwete Minga, Ciza Hamuli, P., Hubert, P., & Marini Djang'Eing'A, R. (2020). Quality of antimalarials in Kinshasa peri-urban areas with regard to local pharmaceutical legislation and regulation. International Health, 12 (4), 253–263. doi:10.1093/inthealth/ihz070
Peer reviewed

Gerometta, E., Grondin, I., Smadja, J., Frederich, M., & Gauvin-Bialecki, A. (2020). A review of traditional uses, phytochemistry and pharmacology of the genus Indigofera. Journal of Ethnopharmacology, 253, 112608. doi:10.1016/j.jep.2020.112608
Peer Reviewed verified by ORBi

Mahadeo, K., Grondin, I., Herbette, G., Palama, T. L., Bouchemal, N., Soulange, J., Laulloo, S. J., Sadeyen, J., Humeau, L., Frederich, M., Gauvin-Bialecki, A., & Kodja, H. (2020). A 1H NMR-based metabolomic approach to study the production of antimalarial compounds from Psiadia arguta leaves (pers.) voigt. Phytochemistry, 176, 112401. doi:10.1016/j.phytochem.2020.112401
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Ledoux, A., Jansen, O., & Frederich, M. (2020). Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents. Planta Medica, 86 (9), 585-618. doi:10.1055/a-1148-9000
Peer Reviewed verified by ORBi

Tanoh, A. E., Blanchard Boué, G., Nea, F., Genva, M., Wognin, E. L., Ledoux, A., Martin, H., Tonzibo, Z. F., Frederich, M., & Fauconnier, M.-L. (2020). Seasonal effect on the chemical composition, insecticidal properties and other biological activities of Zanthoxylum leprieurii Guill. & Perr. essential oils. Foods, 9 (5), 550. doi:10.3390/foods9050550
Peer Reviewed verified by ORBi

Muganga, R., Bero, J., Quetin-Leclercq, J., Angenot, L., Tits, M., Mouithys-Mickalad, A., Franck, T., & Frederich, M. (2020). In vitro Antileishmanial, Antitrypanosomal, and Anti-inflammatory- like Activity of Terminalia mollis Root Bark. Planta Medica, efirst. doi:10.1055/a-1260-6382
Peer Reviewed verified by ORBi

Saive, M., Frederich, M., & Fauconnier, M.-L. (2020). Plants used in traditional medicine in the Comoros archipelago: a review. Biotechnologie, Agronomie, Société et Environnement, 24 (2), 117-141. doi:10.25518/1780-4507.18553
Peer Reviewed verified by ORBi

Kowa, T., Tchokouaha, L., Nyemb, J.-N., Wabo, H., Tchinda, A., Appiah-Opong, R., Agbor, G., Tane, P., & Frederich, M. (January 2020). Antipromastigote and cytotoxic activities of some chemical constituents of Hypericum lanceolatum Lam. Journal of Applied Pharmaceutical Science, 10, 26-32. doi:10.7324/JAPS.2020.101004
Peer Reviewed verified by ORBi

Tomani, J. C. D., Kagisha, V., Tchinda, A. T., Jansen, O., Ledoux, A., Vanhamme, L., Frederich, M., Muganga, R., & Souopgui, J. (2020). The Inhibition of NLRP3 Inflammasome and IL-6 Production by Hibiscus noldeae Baker f. Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials. Molecules, 25 (20), 4693. doi:10.3390/molecules25204693
Peer Reviewed verified by ORBi

Degotte, G., Lempereur, D., Adubofour, Y., Pirotte, B., Frederich, M., & Francotte, P. (11 December 2019). Dimerisation of gallic acid for malaria treatment. Poster session presented at CIRMDay, Liège, Belgium.

Clain, M.-E., Gils, M., Ledoux, A., Desdemoustier, P., Turki, C., Jérusalem, M., Frederich, M., & Castillo Cabello, G. (11 December 2019). Antiplasmodial activity and chemical composition of Belgian mushrooms. Poster session presented at 2nd CIRM Scientific Day.

Gils, M., Ledoux, A., Davoine, C., Desdemoustier, P., Clain, M.-E., Castillo Cabello, G., Frederich, M., & Fillet, M. (11 December 2019). Affinity capillary electrophoresis as a tool for the discovery of new antimalarial natural compounds. Poster session presented at 2nd CIRM Scientific Day.

Turki, C., Ledoux, A., Desdemoustier, P., Bonnet, O., & Frederich, M. (11 December 2019). Contribution to the phytochemical study of Casearia coriaceae Vent. Poster session presented at 2nd CIRM Scientific Day.

Ledoux, A., & Frederich, M. (11 December 2019). Antiplasmodial and antimalarial models for the detection of promising natural compounds. Paper presented at Mission de Coopération au Développement, Butare, Rwanda.

Bonnet, O., Bovy, M., Beniddir, M. A., Champy, P., & Frederich, M. (11 December 2019). Investigation of the alkaloid composition of Strychnos genus using molecular networking, a mapping method for molecules. Poster session presented at 2nd CIRM Day, Liège, Belgium.

Frederich, M. (06 December 2019). Ethnopharmacology and antimalarial compounds from tropical plants. Paper presented at Biodiversity and health in the tropics, Bruxelles, Belgium.

Degotte, G., Pirotte, B., Frederich, M., & Francotte, P. (22 November 2019). Total synthesis approach: development of new antimalarial compounds. Poster session presented at MedChem 2019, Bruxelles, Belgium.

Degotte, G., Pirotte, B., Frederich, M., & Francotte, P. (05 September 2019). Pharmacomodulation of ellagic acid: a total synthesis approach. Poster session presented at EFMC Young Medicinal Chemist, Athènes, Greece.

Kpadonou, D., Kpoviessi, S., Bero, J., Agbani, P., Gbaguidi, F., Kpadonou-Kpoviessi, B., Sinsin, B., Frederich, M., & Quetin-Leclercq, J. (September 2019). Chemical composition, in vitro antioxidant and antiparasitic properties of the essential oils of three plants used in traditional medicine in Benin. Journal of Medicinal Plant Research, 13 (6), 384-395. doi:10.5897/JMPR2019.6791
Peer Reviewed verified by ORBi

Jansen, O., Desdemoustier, P., Ledoux, A., Marotte, A., DJIERRO, K., Hamann, C., & Frederich, M. (August 2019). SCREENING OF 25 EUPHORBIACEAE FOR THEIR IN VITRO ANTIPLASMODIAL PROPERTIES. Poster session presented at Natural Products in Drug Discovery and Human Health, LISBONNE, Portugal.
Editorial reviewed

Kagisha, V., Frederich, M., Marini Djang'Eing'A, R., & Muganga, R. (20 May 2019). ESTABLISHMENT AND VALIDATION OF CHROMATOGRAPHIC METHODS FOR STANDARDIZATION OF NEORAUTANENIA MITIS, A MEDICINAL PLANT USED IN AN ANTI-SCABIES OINTMENT IN RWANDA. Paper presented at 20 th Forum of Pharmaceutical Sciences, Brussels, Belgium.

Ledoux, A., Coelho Cristino Mamede, L. C., Jansen, O., Desdemoustier, P., Palazzo, C., Hamann, C., Piel, G., & Frederich, M. (17 May 2019). Natural compound-containing liposomes: a strategy for targeted activities toward artemisinin-resistant Plasmodium falciparum isolate. Poster session presented at 4th Phytoday, Belgium.
Peer reviewed

Bonnet, O., Beniddir, M. A., Champy, P., & Frederich, M. (17 May 2019). Exploring the chemical space of Strychnos species through a multi-informative molecular network. Poster session presented at 4th Phytoday, Bruxelles, Belgium.

Kagisha, V., Frederich, M., Marini Djang'Eing'A, R., MUGANGA, R., Ledoux, A., Jansen, O., & katembezi, A. (17 May 2019). ESTABLISHMENT AND VALIDATION OF CHROMATOGRAPHIC METHODS FOR STANDARDIZATION OF NEORAUTANENIA MITIS, A MEDICINAL PLANT USED IN AN ANTI-SCABIES OINTMENT IN RWANDA. Poster session presented at 4e' edition du Phytoday, Bruxelles, Belgium.

Ranarivelo, N., Randriamialinoro, F., Rakotondrafara, A., Rakotonandrasana, S., Michel, S., Deguin, B., Ratsimbason, M., Ranarivelo, L., Rasoarahona, J., Frederich, M., & Ralambonirina, S. (17 May 2019). Triterpenoid and steroid coumponds isolated from leaves of Hyperacanthus thouvenotii (Rubiaceae), endemic plant from Madagascar. Paper presented at Phytoday 2019, 4th edition, Brussels, Belgium.

Degotte, G., Alson, S., Hans, A., Jansen, O., Cieckiewicz, E., Rakotoarimanana, H., Rafatro, H., Randimbivololona, F., Francotte, P., & Frederich, M. (2019). Antiplasmodial activity of polyphenolic derivatives. Pharmaceuticals.
Peer Reviewed verified by ORBi

Nouet, C., Liénard, A., Colinet, G., Scholl, G., De Pauw, E., Bodson, B., Frederich, M., & Hanikenne, M. (May 2019). Phytomanagement of industrial wasteland during pre- and post-remediation periods: ECOSOL, a case study in the Walloon region. Poster session presented at 15th International Conference on the Biogeochemistry of Trace Elements (ICOBTE), Nanjing, China.

Degotte, G., Halleux, A., Pirotte, B., Francotte, P., & Frederich, M. (May 2019). Design of new antimalarials inspired by ellagic acid through a total synthesis approach. Poster session presented at Phytoday, Bruxelles, Belgium.

Frederich, M., & BARTSCH, P. (2019). 1. Qu'est-ce que le tabac? D'où vient-il ? Quelle est son histoire ? In V. Seutin, J'arrête de fumer. Comprendre son addiction pour mieux la vaincre. Editions Mardaga.
Peer reviewed

Campos, P.-E., Pichon, E., Moriou, C., Clerc, P., Trépos, R., Frederich, M., De Voogd, N., Hellio, C., Gauvin-Bialecki, A., & Al-Mourabit, A. (2019). New Antimalarial and Antimicrobial Tryptamine Derivatives from the Marine Sponge Fascaplysinopsis reticulata. Marine Drugs, 17 (3), 167. doi:10.3390/md17030167
Peer Reviewed verified by ORBi

Ielciu, I.-I., Mouithys-Mickalad, A., Franck, T., Angenot, L., Ledoux, A., Păltinean, R., Cieckiewicz, E., Etienne, D., Tits, M., Crişan, G., & Frederich, M. (2019). Flavonoid composition, cellular antioxidant activity and (myelo)peroxidase inhibition of a Bryonia alba L. (Cucurbitaceae) leaves extract. Journal of Pharmacy and Pharmacology, 71, 230-239. doi:10.1111/jphp.13025
Peer Reviewed verified by ORBi

Kowa, T. K., Tchokouaha, L. R. Y., Cieckiewicz, E., Philips, T. J., Dotse, E., Wabo, H. K., Tchinda, A. T., Tane, P., & Frederich, M. (2019). Antileishmanial and cytotoxic activities of a new limonoid and a new phenyl alkene from the stem bark of Trichilia gilgiana (Meliaceae). Natural Product Research, 0 (0), 1-7. doi:10.1080/14786419.2018.1553879
Peer Reviewed verified by ORBi

Assaidi, A., Dib, I., Tits, M., Angenot, L., Bellahcen, S., Bouanani, N., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., Frederich, M., & Ziyyat, A. (2019). Chenopodium ambrosioides induces an endothelium-dependent relaxation of rat isolated aorta. Journal of Integrative Medicine, 17 (2), 115 - 124. doi:10.1016/j.joim.2019.01.006
Peer reviewed

Mahadeo, K., Herbette, G., Grondin, I., Jansen, O., Kodja, H., Soulange, J., Jhaumeer-Laulloo, S., Clerc, P., Gauvin-Bialecki, A., & Frederich, M. (2019). Antiplasmodial Diterpenoids from Psiadia arguta. Journal of Natural Products, 82 (5), 1261-1266. doi:10.1021/acs.jnatprod.8b00698
Peer Reviewed verified by ORBi

Mutwale Kapepula, P., Baku Ngumbi, P., Kasongo Kawayidiko, M., Duki Mpanzu, A., Franck, T., Mouithys-Mickalad, A., Frederich, M., Ngombe Kabamba, N., & Masiala Tsobo, C. (2019). Anti-inflammatory and antioxidant activities of Rungia congoensis, a traditional vegetable consumed by Yombe people from Kongo Central area (DR. Congo). Natural Product Research, 1-5. doi:10.1080/14786419.2018.1425847
Peer Reviewed verified by ORBi

Ielciu, I., Frederich, M., Hanganu, D., Angenot, L., Olah, N.-K., Ledoux, A., Crișan, G., & Păltinean, R. (2019). Flavonoid Analysis and Antioxidant Activities of the Bryonia alba L. Aerial Parts. Antioxidants, 8 (4 108). doi:10.3390/antiox8040108
Peer Reviewed verified by ORBi

Fox Ramos, A. E., Le Pogam, P., Fox Alcover, C., Otogo N'Nang, E., Cauchie, G., Hazni, H., Awang, K., Breard, D., Echavarren, A. M., Frederich, M., Gaslonde, T., Girardot, M., Grougnet, R., Kirillova, M. S., Kritsanida, M., Lemus, C., Le Ray, A.-M., Lewin, G., Litaudon, M., & Beniddir, M. A. (2019). Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research. Scientific Data, 6 (1), 15. doi:10.1038/s41597-019-0028-3
Peer Reviewed verified by ORBi

Huang, Y., Jansen, O., Frederich, M., Mouithys-Mickalad, A., Nys, G., Servais, A.-C., Crommen, J., Jiang, Z., & Fillet, M. (2019). Capillary electrophoresis, high-performance liquid chromatography, and thin-layer chromatography analyses of phenolic compounds from rapeseed plants and evaluation of their antioxidant activity. Journal of Separation Science, 1-10. doi:10.1002/jssc.201800712
Peer Reviewed verified by ORBi

Coelho Cristino Mamede, L. C., Ledoux, A., Desdemoustier, P., Jansen, O., Piel, G., Fillet, M., De Tullio, P., & Frederich, M. (19 December 2018). Quantitative analysis of a natural compound and heparin by HPLC-DAD and 1H NMR for the characterization of a liposomal formulation. Poster session presented at The first CIRM scientific Day, Liège, Belgium.

Degotte, G., Halleux, A., Hans, A., Jansen, O., Ledoux, A., Desdemoustier, P., Pirotte, B., Francotte, P., & Frederich, M. (December 2018). Preparation of ellagic acid derivatives through a total synthesis approach to improve bioavailability. Poster session presented at 1st CIRM Day, Liège, Belgium.

Degotte, G., Francotte, P., Frederich, M., Halleux, A., Hans, A., Jansen, O., Ledoux, A., Desdemoustier, P., & Pirotte, B. (November 2018). Pharmacomodulation of ellagic acid, a promising antiplasmodial agent, to improve its bioavailability. Poster session presented at 30th International Symposium on the Chemistry of Natural Products and the 10th International Conference on Biodiversity, Athens, Greece.

Coelho Cristino Mamede, L. C., Degotte, G., Ledoux, A., Jansen, O., Desdemoustier, P., & Frederich, M. (November 2018). Antiplasmodial activity and interaction between cannabidiol and artemisinin. Poster session presented at 30th International Symposium on the Chemistry of Natural Products and the 10th International Conference on Biodiversity, Athens, Greece.

Ranarivelo, N., Randriamialinoro, F., Rakotondrafara, A., Michel, S., Deguin, B., Ranarivelo, L., Frederich, M., Rasoarahona, J., & Ralambonirina, S. (25 September 2018). Triterpénoïdes et stéroïdes isolés des feuilles de Hyperacanthus thouvenotii (Rubiaceae), une plante endémique de Madagascar. Poster session presented at Colloque Qualité et Valorisation des Produits Agricoles (QVPA 2018), Antananarivo, Madagascar.
Peer reviewed

Tomani, J., Nyirimigabo, A., Tchouate, O., Frederich, M., Muganga, R., & Souopgui, J. (19 September 2018). Antiinflammatory and antileukemic-like activities of R01Yob, a medicinal plant of the rwandese pharmacopeia. Poster session presented at 11th conference of AfSHG (African Society of Human Genetics), Kigali, Rwanda.

Mahadeo, K., Grondin, I., Kodja, H., Thomas, H., Clerc, P., Frederich, M., & Gauvin-Bialecki, A. (03 July 2018). A chemotaxonomic study of 11 species of the genus Psiadia endemic to La Reunion by 1H NMR and GC-MS based metabolomic approach. Paper presented at The International Conference on Pure and Applied Chemistry (ICPAC-2018), Réduit, Mauritius.

Beaufay, C., Ledoux, A., Frederich, M., Quetin-Leclercq, J., Zhao, S., Teijaro, C., Andrade, R., & Jansen, O. (July 2018). Antimalarial and antitrypanosomal activity of strychnogucine B, a bisindole alkaloid from Strychnos icaja. Poster session presented at 3eme symposium international AFERP STOLON.

Degotte, G., Alson, S. G., Hans, A., Jansen, O., Cieckiewicz, E., Rakotoarimanana, H., Rafatro, H., Randimbivololona, F., Francotte, P., & Frederich, M. (12 June 2018). Antiplasmodial activity of polyphenolic derivatives. Poster session presented at 32èmes Journées Franco-Belges de Chimie Thérapeutique et 26èmes Conférences Européennes des Pharmacochimistes de l'Arc Atlantique, Asnelles sur mer, France.

Frederich, M. (07 June 2018). L'ethnopharmacologie, à l'origine de nombreux médicaments : recherches dans le domaine des antipaludiques. Paper presented at 8e Journées Scientifiques du Médicament, Grenoble, France.

Ledoux, A., Coelho Cristino Mamede, L. C., Jansen, O., Hae Choi, Y., & Frederich, M. (23 May 2018). NMR Metabolomic analysis as a tool to identify antiplasmodial compounds in Poupartia borbonica extracts. Poster session presented at 11èmes journées scientifiques du RFMF, Liège, Belgium.

Alson, S. G., Jansen, O., Cieckiewicz, E., Rakotoarimanana, H., Rafatro, H., Degotte, G., Francotte, P., & Frederich, M. (2018). In-vitro and in-vivo antimalarial activity of caffeic acid and some of its derivatives. Journal of Pharmacy and Pharmacology, 70 (10), 1349-1356. doi:10.1111/jphp.12982
Peer Reviewed verified by ORBi

Saive, M., Frederich, M., & Fauconnier, M.-L. (2018). Plants used in traditional medicine and cosmetics in Mayotte Island (France): An ethnobotanical study. Indian Journal of Traditional Knowledge, 17 (4), 645-653.
Peer Reviewed verified by ORBi

Mahadeo, K., Grondin, I., Kodja, H., Soulange Govinden, J., Jhaumeer Laulloo, S., Frederich, M., & Gauvin-Bialecki, A. (2018). The genus Psiadia: Review of traditional uses, phytochemistry and pharmacology. Journal of Ethnopharmacology, 210, 48-68. doi:10.1016/j.jep.2017.08.023
Peer Reviewed verified by ORBi

Ielciu, I., Hanganu, D., Ramona, P., Vlase, L., Frederich, M., Gheldiu, A.-M., Benedec, D., & Cri, G. (2018). Antioxidant capacity and polyphenolic content of the Echinocystis lobata (Michx.) Torr. et A.Gray flowers. Pakistan Journal of Pharmaceutical Sciences, 31 (2), 677-684.
Peer Reviewed verified by ORBi

Tomani, J. C. D., Gainkam, L. O. T., Nshutiyayesu, S., Mukazayire, M. J., Ribeiro, S. O., Stevigny, C., Frederich, M., Muganga, R., & Souopgui, J. (2018). An ethnobotanical survey and inhibitory effects on NLRP3 inflammasomes/Caspase-1 of herbal recipes' extracts traditionally used in Rwanda for asthma treatment. Journal of Ethnopharmacology, 227, 29-40. doi:10.1016/j.jep.2018.08.016
Peer Reviewed verified by ORBi

Ledoux, A., Cao, M., Jansen, O., Coelho Cristino Mamede, L. C., Campos, P.-E., Payet, B., Clerc, P., Grondin, I., Girard-Valenciennes, E., Hermann, T., Litaudon, M., Vanderheydt, C., Delang, L., Neyts, J., Leyssen, P., Frederich, M., & Smadja, J. (2018). Antiplasmodial, Anti-chikungunya virus and Antioxidant Activities of 64 endemic Plants from the Mascarene Islands. International Journal of Antimicrobial Agents, 52 (5), 622-628. doi:10.1016/j.ijantimicag.2018.07.017
Peer Reviewed verified by ORBi

Beaufays, C.* , Ledoux, A.* , Jansen, O., bordignon, A., Zhao, S., Teijaro, C., Andrade, R., Quetin-Leclercq, J., & Frederich, M. (2018). In vivo antimalarial and antitrypanosomal activity of strychnogucine B, a bisindole alkaloid from Strychnos icaja. Planta Medica, 84, 881-885. doi:10.1055/a-0644-2723
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Apel, C., Bignon, J., Garcia-Alvarez, M. C., Ciccone, S., Clerc, P., Grondin, I., Girard-Valenciennes, E., Smadja, J., Lopes, P., Frederich, M., Roussi, F., Meinnel, T., Giglione, C., & Litaudon, M. (2018). N-myristoyltransferases inhibitory activity of ellagitannins from Terminalia bentzoe (L.) L. f. subsp. bentzoe. Fitoterapia, 131, 91-95. doi:10.1016/j.fitote.2018.10.014
Peer Reviewed verified by ORBi

Gbaweng, A. J. Y., Dairou, H., Zingue, S., Emmanuel, T., Tchinda, A. T., Frederich, M., & Mbafor, J. T. (2018). Excelsanone, a new isoflavonoid from Erythrina excelsa (Fabaceae), with in vitro antioxidant and in vitro cytotoxic effects on prostate cancer cells lines. Natural Product Research, 1-9. doi:10.1080/14786419.2018.1495639
Peer Reviewed verified by ORBi

Campos, Pichon, E., Illien, B., Clerc, P., Moriou, C., de Voogd, N., Hellio, C., Trépos, R., Frederich, M., Al-mourabit, A., & Gauvin-Bialecki, A. (2018). (2S*,5S*,6Z)-2,5-Epoxydocosan-6-en-21-ynoic Acid, New Fatty Acid from the Marine Sponge Haliclona fascigera. Natural Products Chemistry and Research, 6 (5), 336. doi:10.4172/2329-6836.1000336
Peer reviewed

Douanla, P. D., Tchuendem, M. H. K., Tchinda, A. T., Kuiate, T., Zofou, D., Cieckiewicz, E., Frederich, M., & Nkengfack, A. E. (2018). Chemical Constituents of the Leaves of Caloncoba welwitschii Gilg. Phytochemistry Letters, 23 (October 2017), 5--8. doi:10.1016/J.PHYTOL.2017.10.019
Peer Reviewed verified by ORBi

Frederich, M. (06 December 2017). Les plantes tropicales, sources potentielles de médicaments antipaludiques . Paper presented at Conférence à l'Académie Nationale de Pharmacie, Paris, Paris, France.

Cao, M., Karim, R., CATALDO, D., Frederich, M., Evrard, B., & Piel, G. (December 2017). Pulmonary delivery of a liposome formulation encapsulating a natural flavonoid in the treatment of lung cancer. Poster session presented at Martine Cao, Bordeaux, France.

Mavungu Landu, D. J., Frederich, M., Hubert, P., Manzambi Kuwekita, J., Reginster, J.-Y., Michel, B., Gretry, L., Mbongo Pasi, C., Mavungu Nsiona, J., Mbinze, J., & Marini Djang'Eing'A, R. (23 November 2017). Consommation des médicaments antipaludiques : Analyse des échantillons et caractéristiques des pharmacies en territoires périurbains de Kinshasa. Paper presented at Premier Congrès sur la Gestion Intégrée du Risque Sanitaire (COGIRS I), Kinshasa, Congo - Kinshasa.

Frederich, M. (20 November 2017). Traitement de la drépanocytose par des phytomédicaments traditionnels : le cas du Zanthoxylum zanthoxyloïdes au Burkina faso . Paper presented at Journée d’étude autour des maladies génétiques : enjeux et défis interdisciplinaires dans un monde globalisé.

Mavungu Landu, D. J., Mbuyi Kaluka Tshibanda, J., Dasnoy, C., Gretry, L., Mikobi Mikobi, C., Kayembe, J. M., Longo Mbenza, B., Marini Djang'Eing'A, R., Hubert, P., Reginster, J.-Y., Michel, B., Manzambi Kuwekita, J., Jansen, O., & Frederich, M. (10 November 2017). Processus d’intégration de la Médecine traditionnelle dans le système national de soins de la République Démocratique du Congo : Cas de trois zones de santé de Kinshasa. Paper presented at Médecines en Afrique, entre tradition et modernité, Liège, Belgium.

Frederich, M. (10 November 2017). L’ethnopharmacologie, à l’origine de nombreux médicaments. Paper presented at Colloque du PACODEL-ULiège : «  Médecines en Afrique, entre tradition et modernité », Musée Curtius, Liège, Belgium.

Mavungu Landu, D. J., Mikobi Mikobi, C., Beya, R., Pipo Tshiasuma, M., Kayembe, J. M., Gretry, L., Marini Djang'Eing'A, R., Hubert, P., Reginster, J.-Y., Michel, B., Manzambi Kuwekita, J., & Frederich, M. (10 November 2017). Expérience de l’intégration des cours de Médecine traditionnelle dans la Faculté de Médecine de l’Université Notre-Dame du Kasayi à Kananga. Paper presented at Médecines en Afrique, entre tradition et modernité, Liège, Belgium.

Mavungu Landu, D. J., Liégeois, S., Manzambi Kuwekita, J., Mbinze Kindenge, J., Mavungu Nsiona, J., Hubert, P., Michel, B., Reginster, J.-Y., Frederich, M., Marini Djang'Eing'A, R., & Gretry, L. (13 October 2017). The quality of artemether-lumefantrine combination and characteristics of pharmacies in the periurban areas of kinshasa (Kwete Minga, M., Trans.). Tropical Medicine and International Health, 22 (1), 76.
Peer Reviewed verified by ORBi

Marini Djang'Eing'A, R., Batina Agasa, S., Gulbis, B., BOURS, V., Razy, E., Frederich, M., Guillaume, M., Etienne, A.-M., Mbinze Kindenge, J., Kimoni Kicha, ALWORONG’A OPARA ATIM-NEDI, J.-P., BORIVE AMANI, M., KASONGO MALOBA, P., OPESA LOHATA, A., BANSANDJA LONGEMBE, E., MAVINGA TANA, A., & Hubert, P. (06 October 2017). Drepakis : Contribution to the management of Sickle cell disease in the city of Kisangani (D.R. Congo). Paper presented at 5th Annual International Scientific Conference Society for the Advancement of Science in Africa (SASA) and 2nd Rwanda Biotechnology Conference, Kigali, Rwanda.

Katemo Muhoya, F., Kadima Ntokamunda, J., Njakarinala Ranarivelo, Frederich, M., Hubert, P., & Marini Djang'Eing'A, R. (05 October 2017). Investigation of content of Panda oleosa (Pierre), a plant used in Kisangani areas for its antihyperglycemic activity. Paper presented at 5th Annual International Scientific Conference Society for the Advancement of Science in Africa (SASA) and 2nd Rwanda Biotechnology Conference, Kigali, Rwanda.

Katemo Muhoya, F., Kadima Ntokamunda, J., Njakarinala Ranarivelo, Frederich, M., Hubert, P., & Marini Djang'Eing'A, R. (11 September 2017). Preliminary Phytochemical Content and Antidiabetic Potential Investigations of Panda oleosa (Pierre) Used in Kisangani Areas. American Journal of Analytical Chemistry, 8, 564-581. doi:10.4236/ajac.2017.89041
Peer reviewed

Bordignon, A., Frederich, M., Ledoux, A., Campos, P.-É., Clerc, P., Hermann, T., Quetin-Leclercq, J., & Cieckiewicz, E. (2017). In vitro antiplasmodial and cytotoxic activities of sesquiterpene lactones from Vernonia fimbrillifera Less. (Asteraceae). Natural Product Research, 1-4. doi:10.1080/14786419.2017.1350665
Peer Reviewed verified by ORBi

Habyarimana, J. B. A., Baise, E., Douny, C., Weber, M., BOEMER, F., De Tullio, P., Franck, T., Marcillaud-Pitel, C., Frederich, M., Mouithys-Mickalad, A., Richard, E., Scippo, M.-L., Votion, D., & Gustin, P. (2017). Development of an HPTLC method for determination of hypoglycin A in aqueous extracts of seedlings and samaras of Acer species. Eprint/Working paper retrieved from https://orbi.uliege.be/2268/212226. doi:10.1101/148262

Paul, A., Frederich, M., Caparros Megido, R., Alabi, T., Malik, P., Uyttenbroeck, R., Francis, F., Blecker, C., Haubruge, E., Lognay, G., & Danthine, S. (June 2017). Insect fatty acids: A comparison of lipids from three Orthopterans and Tenebrio molitor L. larvae. Journal of Asia-Pacific Entomology, 20 (2), 337-340. doi:10.1016/j.aspen.2017.02.001
Peer Reviewed verified by ORBi

Ielciu, I.-I., Vlase, L., Frederich, M., Hanganu, D., Păltinean, R., Cieckiewicz, E., Olah, N.-K., Gheldiu, A.-M., & Crişan, G. (03 May 2017). Polyphenolic profile and biological activities of the leaves and aerial parts of Echinocystis lobata (Michx.) Torr. et A.Gray (Cucurbitaceae). Farmacia, 65 (2), 179-183.
Peer reviewed

Campos, P.-E., Wolfender, J.-L., Quieroz, E. F., Marcourt, L., Al-Mourabit, A., Frederich, M., Bordignon, A., De Voogd, N., Illien, B., & Gauvin-Bialeki, A. (10 April 2017). Unguiculin A and Ptilomycalins E-H, Antimalarial Guanidine Alkaloids from the Marine Sponge Monanchora unguiculata. Journal of Natural Products, 80, 1404-1410. doi:10.1021/acs.jnatprod.6b01079
Peer Reviewed verified by ORBi

Nouet, C., Bodson, B., Colinet, G., De Pauw, E., Frederich, M., Nguyen, B. K., & Hanikenne, M. (16 March 2017). Attractiveness, greening and valorization of industrial wasteland during pre- and post-sanitation periods. Poster session presented at Intersol 2017, Lyon, France.

Issac, M., Aknin, M., Gauvin-Bialecki, A., De Voogd, N., Ledoux, A., Frederich, M., Kashman, Y., & Carmeli, S. (16 February 2017). Cyclotheonellazoles A–C, Potent Protease Inhibitors from the Marine Sponge Theonella aff. swinhoei. Journal of Natural Products, 80, 1110-1116. doi:10.1021/acs.jnatprod.7b00028
Peer Reviewed verified by ORBi

Dib, I., Tits, M., Angenot, L., Wauters, J. N., Assaidi, A., Mekhfi, H., Aziz, M., Bnouham, M., Legssyer, A., Frederich, M., & Ziyyat, A. (2017). Antihypertensive and vasorelaxant effects of aqueous extract of Artemisia campestris L. from Eastern Morocco. Journal of Ethnopharmacology, 206, 224-235. doi:10.1016/j.jep.2017.05.036
Peer Reviewed verified by ORBi

Jansen, O., Tchinda, A. T., Loua, J., Esters, V., Cieckiewicz, E., Ledoux, A., Toukam, P. D., Angenot, L., Tits, M., Balde, A. M., & Frederich, M. (2017). Antiplasmodial activity of Mezoneuron benthamianum leaves and identification of its active constituents. Journal of Ethnopharmacology, 203 (March), 20--26. doi:10.1016/j.jep.2017.03.021
Peer Reviewed verified by ORBi

Kapepula, P. M., Kabamba Ngombe, N., Tshisekedi Tshibangu, P., Tsumbu, C., Franck, T., Mouithys-Mickalad, A., Mumba, D., Tshala-Katumbay, D., Serteyn, D., Tits, M., Angenot, L., Kalenda, P. D. T., & Frederich, M. (2017). Comparison of metabolic profiles and bioactivities of the leaves of three edible Congolese Hibiscus species. Natural Product Research, 6419 (March), 1--8. doi:10.1080/14786419.2017.1305382
Peer Reviewed verified by ORBi

Mahadeo, K., Grondin, I., Kodja, H., Soulange Govinden, J., Jhaumeer Laulloo, S., Herbette, G., Frederich, M., & Bialecki, A. (2017). Metabolomic study and pharmacological valorisation of species of the genus Psiadia endemic to Reunion and Mauritius islands. Poster session presented at BioHealF 2017 -International Conference on Biodiversity, Health and Food, Saint-Denis, Réunion.

Ebralidze, L., Mskhiladze, L., Ledoux, A., Frederich, M., Bellahcene, A., Bero, J., Quetin-Leclercq, J., & Bakuridze, A. (2017). ANTICANCER, ANTIPLASMODIAL AND ANTITRYPANOSOMAL ACTIVITIES OF CRUDE EXTRACTS OF PLATANUS ORIENTALIS. World Journal of Pharmaceutical Research, 6 (3), 170-175. doi:10.20959/wjpr20173-7985
Peer reviewed

Ledoux, A., St-Gelais, A., Cieckiewicz, E., Jansen, O., Bordignon, A., Illien, B., Di Giovanni, N., Marvilliers, A., Hoareau, F., Pendeville-Samain, H., Leclercq, J., & Frederich, M. (2017). Antimalarial Activities of Alkyl Cyclohexenone Derivatives Isolated from the Leaves of Poupartia borbonica. Journal of Natural Products, 80 (6), 1750-1757. doi:10.1021/acs.jnatprod.6b01019
Peer Reviewed verified by ORBi

Tshisekedi Tshibangu, P., Mutwale Kapepula, P., Kabongo Kapinga, M. J., Tujibikila Mukuta, A., Kalenda, D. T., Tchinda, A. T., Mouithys-Mickalad, A., Jansen, O., Cieckiewicz, E., Tits, M., Angenot, L., & Frederich, M. (2017). Antiplasmodial activity of Heinsia crinita (Rubiaceae) and identification of new iridoids. Journal of Ethnopharmacology, 196, 261-266. doi:10.1016/j.jep.2016.11.041
Peer Reviewed verified by ORBi

Gianfrancesco, M., Dehairs, J., Bloch, K., L’homme, L., Jansen, O., Frederich, M., Piette, J., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (2017). Implication du remodelage de la membrane plasmique par les acides gras dans la régulation de l’activité de l’inflammasome NLRP3 dans des macrophages humains. Nutrition Clinique et Metabolisme, 31 (3), 255. doi:10.1016/j.nupar.2017.06.002
Peer Reviewed verified by ORBi

Bahati, L. M., Kapepula, P. M., Kabamba, N. N., Moni, B., Kafuti, G. M., Mungitshi, M., Pambu, A., Bongo, G., Mukuta, A. T., Kabengele, J. K., Mutunda, C. M., Frederich, M., & Fundu, T. M. (2017). Microscopic Features , Chromatographic Fingerprints and Antioxidant Property of Some Unconventional Green Leafy Vegetables Consumed in Bandundu , DR Congo. Pharmacognosy Communications, 7 (4), 158--163.
Peer reviewed

Govinden-Soulange, J., Lobine, D., Frederich, M., Kodja, H., Coetzee, M. P. A., & Ranghoo-Sanmukhiya, V. M. (2017). Metabolomic and molecular signatures of Mascarene Aloes using a multidisciplinary approach. South African Journal of Botany, 108, 137-143. doi:10.1016/j.sajb.2016.10.002
Peer Reviewed verified by ORBi

Mavungu Landu, D. J., Liégeois, S., Manzambi Kuwekita, J., Mbinze Kindenge, J., Hubert, P., Michel, B., Reginster, J.-Y., Frederich, M., & Marini Djang'Eing'A, R. (14 December 2016). Qualité des médicaments antipaludéens et caractéristiques des pharmacies des territoires périurbains de Kinshasa. Poster session presented at CONGRES INTERNATIONAL DE LA PATHOLOGIE INFECTIEUSE ET PARASITAIRE, Kinshasa, Congo - Kinshasa.

Paul, A., Frederich, M., Uyttenbroeck, R., Malik, P., Filocco, S., Richel, A., Heuskin, S., Alabi, T., Caparros Megido, R., Franck, T., Bindelle, J., Maesen, P., Francis, F., Lognay, G., Blecker, C., Haubruge, E., & Danthine, S. (December 2016). Nutritional Composition and Rearing Potential of the Meadow Grasshopper (Chorthippus parallelus Zetterstedt). Journal of Asia-Pacific Entomology, 19 (4), 1111-1116. doi:10.1016/j.aspen.2016.09.012
Peer Reviewed verified by ORBi

Frederich, M., & Ledoux, A. (16 November 2016). Potential Antimalarials from Tropical Plants and Natural Products. Paper presented at CIRM seminar.

Paul, A., Danthine, S., Mutwale Kapepula, P., Jansen, O., Blecker, C., Heuskin, S., Mouithys-Mickalad, A., Franck, T., Lognay, G., & Frederich, M. (20 September 2016). Valorization of Seeds from Some Field Border Flowering Seeds. Poster session presented at 14th Euro Fed Lipid Congress, Ghent, Belgium.

Bordignon, A., Frederich, M., Cieckiewicz, E., Quetin-Leclercq, J., Smadja, J., & Campos, P.-E. (25 July 2016). Study of the antiplasmodial potential of Vernonia fimbrillifera Less. (Asteraceae) leaves, an endemic plant from Reunion Island. Poster session presented at 9th Joint Natural Product Conference 2016, Copenhagen, Denmark.

Mskhiladze, L., Chincharadze, D., St-Gelais, A., Mshvildadze, V., Pichette, A., Ledoux, A., Tits, M., & Frederich, M. (July 2016). Isolation and Identification of Steroid and Flavonoid Glycosides from the Flowers of Allium gramineum. International Journal of Pharmaceutical Sciences and Drug Research, 8 (4), 240-243.
Peer reviewed

Tchinda Tiabou, A., Loua, J., Esters, V., Cieckiewicz, E., Ledoux, A., Angenot, L., Tits, M., Baldé, A. M., Frederich, M., & Jansen, O. (July 2016). Study of Mezoneuron benthamianum, a plant traditionally used against malaria in Guinea. Poster session presented at 9th Joint Natural Products Conference 2016 Copenhagen, Copenhagen, Denmark.

Ledoux, A., Jansen, O., St-Gelais, A., Cieckiewicz, E., Ielciu, I.-I., Bialecki, A., Bero, J., & Frederich, M. (July 2016). New antimalarial compounds isolated from Poupartia borbonica, a Mascarene Islands endemic plant. Planta Medica, 82 (S01), 1-S381.
Peer Reviewed verified by ORBi

Tshisekedi Tshibangu, P., Mutwale Kapepula, P., Kabongo Kapinga, M. J., Kabika Lupona, H., Kabamba Ngombe, N., Dibungi T. Kalenda, P., Jansen, O., Wauters, J.-N., Tits, M., Angenot, L., Rozet, E., Hubert, P., Marini Djang'Eing'A, R., & Frederich, M. (09 June 2016). Fingerprinting and validation of a LC-DAD method for the analysis of biflavanones in Garcinia kola-based antimalarial improved traditional medicines. Journal of Pharmaceutical and Biomedical Analysis, 128 (2016), 382-390. doi:10.1016/j.jpba.2016.04.042
Peer Reviewed verified by ORBi

Saive, M., Frederich, M., & Fauconnier, M.-L. (01 June 2016). Screening of mahoran plants for cosmetic applications. Poster session presented at 6th International Congress of Aromatic and Medicinal Plants, Coimbra, Portugal.

Kengne, A. B. O., Tene, M., Tchinda Tiabou, A., Tane, P., & Frederich, M. (10 March 2016). Terpenoids from Phaulopsis imbricata (Acanthaceae). Journal of Medicinal Plant Research, 10 (10), 122-129.
Peer Reviewed verified by ORBi

Hamaïdia, M., Barez, P.-Y., Carpentier, A., Lebecque, S., Miazek, K., Paul, A., Neelature Sriramareddy, S., Staumont, B., Danthine, S., Deleu, M., Frederich, M., De Pauw, E., Delaplace, P., Delvigne, F., Goffin, D., Ongena, M., DUYSINX, B., LOUIS, R., cosse, J.-P., & Willems, L. (27 February 2016). From Valeriana officinalis to cancer therapy: the success of a bio-sourced compound. Biotechnologie, Agronomie, Société et Environnement, 20 (S1), 314-320.
Peer Reviewed verified by ORBi

Marquise, N., Chevallier, F., Nassar, E., Frederich, M., Ledoux, A., Halauko, Y. S., Ivashkevich, O. A., Matulis, V. E., Roisnel, T., Dorcet, V., & Mongin, F. (February 2016). Substituted azafluorenones: access from dihalogeno diaryl ketones by palladium-catalyzed auto-tandem processes and evaluation of their antibacterial, antifungal, antimalarial and antiproliferative activities. Tetrahedron, 72 (6), 825-836. doi:10.1016/j.tet.2015.12.050
Peer Reviewed verified by ORBi

Talla, E., Yaya Gbaweng, J., Mokale, L., Abdou, J.-P., Tchinda Tiabou, A., Frederich, M., & Mbafor, J. (2016). Chemical constituents from Erythrina droogmansiana (Fabaceae), radical scavenging and antibacterial potential of some extracts and compounds. Natural Products: An Indian Journal, 12 (1), 12-20.
Peer Reviewed verified by ORBi

Mutwale Kapepula, P., Mbombo Mungitshi, P., Franck, T., Mouithys-Mickalad, A., Mumba Ngoyi, D., Kalenda, P. D. T., Kabamba Ngombe, N., Serteyn, D., Tits, M., Frederich, M., & Tamfum Muyembe, J.-J. (2016). Antioxidant potentiality of three herbal teas consumed in Bandundu rural areas of Congo. Natural Product Research, 1-4. doi:10.1080/14786419.2016.1263844
Peer Reviewed verified by ORBi

Frederich, M., Pirotte, B., Fillet, M., & De Tullio, P. (2016). Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine. Journal of Medicinal Chemistry, 59 (19), 8649–8666. doi:10.1021/acs.jmedchem.5b01335
Peer Reviewed verified by ORBi

Tshilanda, D. D., Mutwale Kapepula, P., Onyamboko, D. V. N., Frederich, M., Ngbolua, K.-T.-N., & Mpiana, P. T. (2016). Chemical Fingerprint and Anti-Sickling Activity of Rosmarinic Acid and Methanolic Extracts from Three Species of Ocimum from DR Congo. Journal of Biosciences and Medicines, 04 (January), 59--68. doi:10.4236/jbm.2016.41008
Peer reviewed

Messi, A. N., Ngo Mbing, J., Ndongo, J. T., Nyegue, M. A., Tchinda, A. T., Yemeda, F. L., Frederich, M., & Pegnyemb, D. E. (2016). Phenolic compounds from the roots of Ochna schweinfurthiana and their antioxidant and antiplasmodial activities. Phytochemistry Letters, 17, 119-125. doi:10.1016/j.phytol.2016.07.011
Peer Reviewed verified by ORBi

Paltinean, R., Toiu, A., Wauters, J.-N., Frederich, M., Tits, M., Angenot, L., Tamas, M., & Crisan, G. (2016). PHYTOCHEMICAL ANALYSIS OF FUMARIA OFFICINALIS L. (FUMARIACEAE). Farmacia, 64 (3), 409-413.
Peer reviewed

Ielciu, I.-I., Frederich, M., Tits, M., Angenot, L., Paltinean, R., Cieckiewicz, E., Crisan, G., & Vlase, L. (2016). BRYONIA ALBA L. AND ECBALLIUM ELATERIUM (L.) A. RICH. - TWO RELATED SPECIES OF THE CUCURBITACEAE FAMILY WITH IMPORTANT PHARMACEUTICAL POTENTIAL. Farmacia, 64 (3), 323-332.
Peer reviewed

Paul, A., Frederich, M., Uyttenbroeck, R., Hatt, S., Malik, P., Lebecque, S., Hamaïdia, M., Miazek, K., Goffin, D., Willems, L., Deleu, M., Fauconnier, M.-L., Richel, A., De Pauw, E., Blecker, C., Monty, A., Francis, F., Haubruge, E., & Danthine, S. (2016). Grasshoppers as a food source? A review. Biotechnologie, Agronomie, Société et Environnement, 20 (AgricultureIsLife), 337-352.
Peer Reviewed verified by ORBi

Miazek, K., Lebecque, S., Hamaïdia, M., Paul, A., Danthine, S., Willems, L., Frederich, M., De Pauw, E., Deleu, M., Richel, A., & Goffin, D. (2016). Sphingolipids: Promising lipid-class molecules with potential applications for industry. A review. Biotechnologie, Agronomie, Société et Environnement, 20 (S1), 321-336.
Peer Reviewed verified by ORBi

Uyttenbroeck, R., Hatt, S., Paul, A., Boeraeve, F., Piqueray, J., Francis, F., Danthine, S., Frederich, M., Dufrêne, M., Bodson, B., & Monty, A. (2016). Pros and cons of flowers strips for farmers. A review. Biotechnologie, Agronomie, Société et Environnement, 20 (s1), 225-235.
Peer Reviewed verified by ORBi

Ielciu, I.-I., Păltinean, R., Cieckiewicz, E., Wauters, J.-N., Tits, M., Crişan, G., Vlase, L., & Frederich, M. (14 October 2015). HPLC-DAD IDENTIFICATION OF SOME FLAVONOIDS FROM THE LEAVES AND AERIAL PARTS OF BRYONIA ALBA L. SPECIES SPONTANEOUS IN THE ROMANIAN FLORA. Poster session presented at 2nd International Conference on Natural Products Utilization: From Plants to Pharmacy Shelf, Plovdiv, Bulgaria.

Bordignon, A., Cieckiewicz, E., Jansen, O., Ledoux, A., Campos, P.-E., Smaja, J., Quetin-Leclercq, J., & Frederich, M. (14 October 2015). Isolation, caracterisation and antiplasmodial activity evaluation of compounds from Reunion Island endemic plants. Poster session presented at 2nd International conference on natural products utilization : from plants to pharmacy shelf (ICNPU), Plovdiv, Bulgaria.

Frederich, M., Jansen, O., Muganga, R., & Kodja, H. (24 September 2015). Medicinal plants, malaria and biotechnology. Paper presented at Applied Biotechnology in Africa, Kigali, Rwanda.

Frederich, M., & Jansen, O. (01 September 2015). Ethnopharmacologie et développement de nouveaux médicaments d’origine naturelle. Paper presented at Conférence à la Faculté de Pharmacie de l'Université de Ouagadougou.

Ledoux, A., Martin, B., De Tullio, P., Tits, M., Wauters, J.-N., Choi, Y. H., Bodson, M., & Frederich, M. (16 July 2015). Metabolomics analysis of Galium odoratum (L.) Scop.: impact of the plant population origin and growth conditions. Poster session presented at 2ème Symposium international AFERP – STOLON, Lyon, France.

Bordignon, A., Cieckiewicz, E., Jansen, O., Ledoux, A., Campos, P.-E., Smaja, J., Quetin-Leclercq, & Frederich, M. (16 July 2015). Isolation and identification of potential antimalarial compounds from endemic plants of Reunion Island. Poster session presented at 2ème symposium international AFERP-STOLON -Biodiversité et substances naturelles-, Lyon, France.

Frederich, M., Jansen, O., Muganga, R., & Tchinda Tiabou, A. (12 July 2015). Ethnopharmacology and malaria in Africa. Paper presented at Traditional medicines: Science meets culture, Mons, Belgium.

Ledoux, A., Bordignon, A., Campos, P.-É., Grondin, I., Smadja, J., & Frederich, M. (July 2015). Screening of medicinal plants from Reunion Island for antimalarial activity. Poster session presented at Joint meeting of the GP-TCM Research Association, the TCM Chemistry Specialty Committee and the TCM Pharmaceutical Analysis Specialty Committee of the World Federation of Chinese Medicine Societies, Mons, Belgium.

Martin, B., Frederich, M., De Tullio, P., Tits, M., Wauters, J.-N., Choi, & Bodson, M. (June 2015). Metabolomics analysis of Galium odoratum (L.) Scop.: impact of the plant population origin and growth conditions. Current Metabolomics, 3.
Peer Reviewed verified by ORBi

Ledoux, A., Jansen, O., Campos, P.-É., Grondin, I., Smadja, J., & Frederich, M. (May 2015). Identification of antiplasmodial compounds isolated from endemic plants of Reunion Island. Paper presented at 18th Forum of Pharmaceutical Sciences.

Ledoux, A., Mareatefau, H., Jansen, O., Etienne, D., quetin-Leclercq, J., Clerc, P., Smadja, J., & Frederich, M. (April 2015). Phytochemical Profile and Biological Activity Evaluation of Zanthoxylum heterophyllum Leaves against Malaria. Planta Medica Letters, 2, 10-e11.
Peer Reviewed verified by ORBi

Paul, A., Frederich, M., Uyttenbroeck, R., Malik, P., Alabi, T., Heuskin, S., Blecker, C., Richel, A., Monty, A., Francis, F., Haubruge, E., Lognay, G., & Danthine, S. (15 March 2015). Food Compounds from Meadow Grasshoppers. Poster session presented at Troisièmes Journées Scientifiques de l'Agro-Alimentaire, Hammamet, Tunisia.

Frederich, M. (23 February 2015). Les plantes qui nous soignent : de la tradition à la médecine moderne. Paper presented at Les conférences de la section des Sciences de l’Institut Grand-Ducal, Luxembourg, Luxembourg.

Sauri, J., Sistare, E., Frederich, M., Tchinda Tiabou, A., Parella, T., Williamson, R. T., & Martin, G. E. (February 2015). Multiplicity editing in long-range heteronuclear correlation NMR experiments: Application to natural products. Poster session presented at 56th Experimental Nuclear Magnetic Resonance Conference, Pacific Grove, California, United States.

Mskhiladze, L., Chincharadze, D., Tits, M., Wauters, J.-N., Bellahcene, A., Castronovo, V., Mouithys-Mickalad, A., Franck, T., & Frederich, M. (2015). Identification of Cytotoxic and Antioxidant Compounds from Allium gramineum Flowers. International Journal of Pharmaceutical Sciences and Drug Research, 7, 78-82.
Peer reviewed

Gros, E., Martin, M.-T., Sorres, J., Moriou, C., Vacelet, J., Frederich, M., Aknin, M., Kashman, Y., Gauvin-Bialecki, A., & Al-Mourabit, A. (2015). Netamines O-S, Five New Tricyclic Guanidine Alkaloids from the Madagascar Sponge Biemna laboutei, and Their Antimalarial Activities. Chemistry and Biodiversity, 12 (11), 1725-33. doi:10.1002/cbdv.201400350
Peer Reviewed verified by ORBi

Sauri, J., Frederich, M., Tchinda, A. T., Parella, T., Williamson, R. T., & Martin, G. E. (2015). Carbon Multiplicity Editing in Long-Range Heteronuclear Correlation NMR Experiments: A Valuable Tool for the Structure Elucidation of Natural Products. Journal of Natural Products, 78 (9), 2236-41. doi:10.1021/acs.jnatprod.5b00447
Peer Reviewed verified by ORBi

Halleux, J.-M., Courtejoie, F., Dawance, S., Fagel, N., Frederich, M., Lebailly, P., Poncelet, M., Rubbers, B., & Bogaert, J. (2015). Territoires périurbains : développement, enjeux et perspectives dans les pays du Sud. Une introduction générale. In J. Bogaert & J.-M. Halleux, Territoires périurbains Développement, enjeux et perspectives dans les pays du Sud (pp. 21-29). Gembloux, Belgium: Presses Agronomiques de Gembloux.
Peer reviewed

Tchinda, A. T., Mouokeu, S. R., Ngono, R. A. N., Ebelle, M. R. E., Mokale, A. L. K., Nono, D. K., & Frederich, M. (2015). A new ent-clerodane diterpenoid from Crassocephalum bauchiense Huch. (Asteraceae). Natural Product Research, 29 (21), 1990-1994. doi:10.1080/14786419.2015.1022541
Peer Reviewed verified by ORBi

Fillet, M., & Frederich, M. (2015). The emergence of metabolomics as a key discipline in the drug discovery process. Drug Discovery Today. Technologies, 13, 19-24. doi:10.1016/j.ddtec.2015.01.006
Peer reviewed

Habyarimana, J. B. A., BOEMER, F., Amory, H., Baise, E., Carlier, J., De Tullio, P., Douny, C., Gault, G., Gustin, P., Fanck, T., Frederich, M., Marcillaud-Pitel, C., Richard, E., Patarin, F., Weber, M., & Votion, D. (2015). Les nouveaux outils de diagnostic et de pronostic de la myopathie atypique. In Proceeding de la 41ème Journée de la Recherche équine.
Peer reviewed

Douanla, P. D., Tabopda, T. K., Tchinda, A. T., Cieckiewicz, E., Frederich, M., Boyom, F. F., Tsabang, N., Yeboah, S., Nkengfack, A. E., & Tchuendem, M. H. K. (2015). Antrocarines A-F, antiplasmodial ergostane steroids from the stem bark of Antrocaryon klaineanum. Phytochemistry, 117, 521-6. doi:10.1016/j.phytochem.2015.07.011
Peer Reviewed verified by ORBi

Paul, A., Frederich, M., Uyttenbroeck, R., Filocco, S., Hatt, S., Malik, P., Monty, A., Francis, F., Blecker, C., & Danthine, S. (2015). PROXIMATE ANALYSIS OF SEEDS FROM SOME FIELD BORDER FLOWERING STRIPS. Scientific Bulletin. Series F, Biotechnologies, XIX.
Peer reviewed

Leenders, J., Frederich, M., & De Tullio, P. (2015). Nuclear magnetic resonance: a key metabolomics platform in the drug discovery process. Drug Discovery Today. Technologies, 13, 39-46. doi:10.1016/j.ddtec.2015.06.005
Peer reviewed

Leverrier, A., Bero, J., Cabrera, J., Frederich, M., Quetin-Leclercq, J., & Palermo, J. A. (2015). Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with in vitro antiplasmodial and antitrypanosomal activities. European Journal of Medicinal Chemistry, 100, 10-7. doi:10.1016/j.ejmech.2015.05.044
Peer Reviewed verified by ORBi

Cieckiewicz, E., Mathieu, V., Angenot, L., Gras, T., Dejaegher, B., De Tullio, P., Pirotte, B., & Frederich, M. (2015). Semisynthesis and in Vitro Photodynamic Activity Evaluations of Halogenated and Glycosylated Derivatives of Pheophorbide a. European Journal of Organic Chemistry, 2015 (27), 6061-6074. doi:10.1002/ejoc.201500387
Peer Reviewed verified by ORBi

Mskhiladze, L., Chincharadze, D., Mshvildadze, V., Pichette, A., Frederich, M., Ollivier, E., & Elias, R. (2015). Steroidal Glycosides from the Flowers of Allium leucanthum. Chemistry of Natural Compounds, 51 (5), 900-904. doi:10.1007/s10600-015-1444-z
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Tsala, D. E., Nnanga, N., Cieckiewicz, E., Kiss, R., Connolly, J. D., & Frederich, M. (November 2014). Two new aromadendrane sesquiterpenes from the stem bark of Alafia multiflora. Natural Product Communications, 9 (12), 1673-1675. doi:10.1177/1934578x1400901202
Peer Reviewed verified by ORBi

Frederich, M., & Lempereur, F. (18 October 2014). L’apport de la médecine traditionnelle à la découverte de nouveaux medicaments. Enjeux, problèmes et exemples”. Paper presented at Conférence au centre d’études d’histoire de la pharmacie et du medicament, Woluwe St Lambert, Belgium.

Tshisekedi Tshibangu, P., Kalenda Dibungi, P., Rozet, E., Marini Djang'Eing'A, R., Tits, M., & Frederich, M. (June 2014). INVESTIGATION OF TWO IMPROVED TRADITIONAL MEDICINES: DEVELOPMENT AND VALIDATION OF A LC-UV METHOD FOR THE DOSAGE OF A TRACER COMPOUND. Poster session presented at 10th International Symposium on Drug Analysis / 25th International Symposium on Pharmaceutical and Biomedical Analysis, Liège, Belgium.

Danthine, S., Blecker, C., Paul, A., Caparros Megido, R., Haubruge, E., Alabi, T., Lognay, G., Fauconnier, M.-L., Frederich, M., & Francis, F. (16 May 2014). Mealworms: Alternate Source of Lipids. Paper presented at International Conference: Insects to Feed the World, Ede, Netherlands.

Paul, A., Frederich, M., Blecker, C., Haubruge, E., Francis, F., Caparros Megido, R., Uyttenbroeck, R., Alabi, T., Heuskin, S., Lognay, G., & Danthine, S. (14 May 2014). Belgian Grasshoppers: A Nutritious Food Source. Poster session presented at International Conference: Insects to Feed the World, Ede, Netherlands.

Paul, A., Frederich, M., Uyttenbroeck, R., Hatt, S., Blecker, C., Francis, F., Monty, A., Haubruge, E., & Danthine, S. (08 May 2014). Locusts and Grasshoppers: Future Foods? Paper presented at 4th International Conference on Updating Food Technology: A challenge towards Public Health Nutrition, New Delhi, India.

Gros, E., Al-Mourabit, A., Martin, M.-T., Sorres, J., Vacelet, J., Frederich, M., Aknin, M., Kashman, Y., & Gauvin-Bialecki, A. (April 2014). Netamines H-N, Tricyclic Alkaloids from the Marine Sponge Biemna laboutei and Their Antimalarial Activity. Journal of Natural Products, 77 (4), 818-23. doi:10.1021/np4009283
Peer Reviewed verified by ORBi

Paul, A., Frederich, M., Cieckiewicz, E., Blecker, C., Heuskin, S., Lognay, G., & Danthine, S. (April 2014). Chemical analyses of the seeds from Prunella vulgaris: A chemotaxonomic approach. Poster session presented at 2nd Scientific Meeting of the Food: JSAA 2014, Tunisia.

Paul, A., Danthine, S., Blecker, C., Heuskin, S., Lognay, G., & Frederich, M. (05 March 2014). Some Interesting Sources of Plant Seed Oil. Poster session presented at ENVITAM PhD Day 2014, Louvain-la-Neuve, Belgium.

Paul, A., Danthine, S., Heuskin, S., Lognay, G., & Frederich, M. (07 February 2014). Field bordering flower strips as source of lipids. Poster session presented at 19th National Symposium on Applied Biological Sciences, Gembloux, Belgium.

Uyttenbroeck, R., Hatt, S., Paul, A., Boeraeve, F., Francis, F., Danthine, S., Frederich, M., Dufrêne, M., Bodson, B., & Monty, A. (07 February 2014). Biodiversity and ecosystem services: think functional! Poster session presented at National Symposium on Applied Biological Sciences, Gembloux, Belgium.

Frederich, M. (20 January 2014). « Les plantes qui nous soignent : de la tradition à la médecine moderne ». Paper presented at Les grandes conférences de l'Université de Liège à Verviers.

Kpoviessi, S., Bero, J., Agbani, P., Gbaguidi, F., Kpadonou-Kpoviessi, B., Sinsin, B., Accrombessi, G., Frederich, M., Moudachirou, M., & Quetin-Leclercq, J. (2014). Chemical composition, cytotoxicity and in vitro antitrypanosomal and antiplasmodial activity of the essential oils of four Cymbopogon species from Benin. Journal of Ethnopharmacology, 151, 652-659. doi:10.1016/j.jep.2013.11.027
Peer Reviewed verified by ORBi

Yaya, A., Feumba, R., Emmanuel, T., Tchinda Tiabou, A., Frederich, M., Oben, J., & Mbafor, J. (2014). Antioxidant Activity of Compounds Isolated from the Root Woods of Erythrina droogmansiana. International Journal of Pharmaceutical Sciences and Drug Research, 6 (2), 160-163.
Peer reviewed

Perera, W., Wauters, J.-N., Kevers, C., Frederich, M., & Dommes, J. (2014). Caffeoylquinic acid derivatives from Cuban species of Pluchea Cass. (Asteraceae). Poster session presented at XXIII Simposio de plantas medicinas do Brasil.

Kpadonou Kpoviessi, B. G. H., Kpoviessi, S. D. S., Yayi Ladekan, E., Gbaguidi, F., Frederich, M., Moudachirou, M., Quetin-Leclercq, J., Accrombessi, G. C., & Bero, J. (2014). In vitro antitrypanosomal and antiplasmodial activities of crude extracts and essential oils of Ocimum gratissimum Linn from Benin and influence of vegetative stage. Journal of Ethnopharmacology, 155 (3), 1417-23. doi:10.1016/j.jep.2014.07.014
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Agbor, G., Tsala, D., Yaya, A., Nga, E., Talla, E., Wauters, J.-N., & Frederich, M. (2014). Antioxidant Activity of Flavonoids Isolated From the Fruits of Xylopia parviflora (A. Rich.) Benth. International Journal of Pharmaceutical Sciences and Drug Research, 6, 253-258.
Peer reviewed

Muganga, R., Angenot, L., Tits, M., & Frederich, M. (2014). In Vitro and In Vivo Antiplasmodial Activity of Three Rwandan Medicinal Plants and Identification of Their Active Compounds. Planta Medica, 80 (6), 482-489. doi:10.1055/s-0034-1368322
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Jansen, O., Nyemb, J.-N., Tits, M., Dive, G., Angenot, L., & Frederich, M. (2014). Strychnobaillonine, an Unsymmetrical Bisindole Alkaloid with an Unprecedented Skeleton from Strychnos icaja Baill. Roots. Journal of Natural Products, 77, 1078-1082.
Peer Reviewed verified by ORBi

Matheus, N., Hansen, S., Rozet, E., Peixoto, P., Maquoi, E., LAMBERT, V., Noël, A., Frederich, M., Mottet, D., & De Tullio, P. (January 2014). An Easy, Convenient Cell and Tissue Extraction Protocol for Nuclear Magnetic Resonance Metabolomics. Phytochemical Analysis, 25, 342-349. doi:10.1002/pca.2498
Peer Reviewed verified by ORBi

Perera Cordoba, W. H., Wauters, J.-N., Kevers, C., Frederich, M., & Dommes, J. (2014). Antioxidant fractions and phenolic constituents from leaves of Pluchea carolinensis and Pluchea rosea. Free Radicals and Antioxidants, 4 (2), 1-7. doi:10.5530/fra.2014.2.1
Peer reviewed

Kopa, T. K., Tchinda Tiabou, A., Tala, M. F., Zofou, D., Jumbam, R., Wabo, H. K., Titanji, V. P. K., Frederich, M., Tan, N. H., & Tane, P. (January 2014). Antiplasmodial anthraquinones and hemisynthetic derivatives from the leaves of Tectona grandis (Verbenaceae). Phytochemistry Letters, 8, 41-45. doi:10.1016/j.phytol.2014.01.010
Peer Reviewed verified by ORBi

zidane, A., Tits, M., Angenot, L., Wauters, J.-N., Frederich, M., Dib, I., Mekhfi, H., Aziz, M., Bnouham, M., Abdelkhaleq, L., & Ziyyat, A. (2014). Phytochemical analysis of Tetraclinis articula in relation to its vasorelaxant property. Journal of Materials and Environmental Science, 5 (5), 1368-1375.
Peer Reviewed verified by ORBi

Ledoux, A., Groeber, S., Gallé, J.-B., Jansen, O., Frederich, M., & Nicolas, J.-P. (19 December 2013). Approche ethnobotanique des savoirs traditionnels et de l’utilisation des plantes médicinales appliqués à la période périnatale dans le Sud-Ouest de Madagascar. Poster session presented at Territoires périurbains dans les pays du Sud, Colloque Pacodel.

Danthine, S., Blecker, C., Paul, A., Frederich, M., Alabi, T., Lognay, G., Fauconnier, M.-L., & Francis, F. (December 2013). Physicochemical properties of lipids extracted from Tenebrio molitor larvae. Poster session presented at 7th INTERNATIONAL FOOD CONVENTION(IFCON), India.

Paul, A., Danthine, S., Frederich, M., Uyttenbroeck, R., & Francis, F. (December 2013). Grasshoppers: Food Security & Nutrition. Paper presented at International Conference on Food Technology: Impact on Nutrition and Health (ICFIN-2013), New Delhi, India.

Frederich, M., & Lempereur, F. (17 September 2013). L'apport de la médecine traditionnelle à la découverte de nouveaux médicaments. Enjeux, problèmes et exemples. Paper presented at Cours du Collège Belgique de l'Académie Royale de Médecine.

Getia, M., Mshvildadze, V., Dekanosidze, G., Wauters, J.-N., Tits, M., & Frederich, M. (17 June 2013). Some natural products from aerial parts of Scrophularia imerethica. Poster session presented at International Symposium on Medicinal plants and Natural Product, Montreal, Canada.

Frederich, M. (25 May 2013). Les substances naturelles dans la lutte contre le paludisme. Paper presented at Conférences de l'Académie Royale de Médecine de Belgique, Bruxelles, Belgium.

Marini Djang'Eing'A, R., Fillet, M., Vancauwenberghe, R., Crommen, J., Frederich, M., & Hubert, P. (24 April 2013). Falsification des médicaments: mythe ou réalité ? Paper presented at Cours-conférences 2013 Sciences Biologiques et Médicales, Namur, Belgium.

Esters, V., Karangwa, C., Tits, M., Francotte, P., Pirotte, B., Servais, A.-C., Fillet, M., Crommen, J., Robbrecht, E., MINET, A., Grisar, T., Angenot, L., & Frederich, M. (March 2013). Unusual Amino Acids and Monofluoroacetate from Dichapetalum michelsonii (Umutambasha), a Toxic Plant from Rwanda. Planta Medica, 79, 334-337. doi:10.1055/s-0032-1328283
Peer Reviewed verified by ORBi

Denooz, R., VAN HEUGEN, J.-C., Frederich, M., De Tullio, P.* , & Charlier, C.*. (March 2013). Identification and structure elucidation of four cannabimimetic compounds in seized products. Journal of Analytical Toxicology, 37 (2), 56-63. doi:10.1093/jat/bks095
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* These authors have contributed equally to this work.

Jonville, M.-C., Dive, G., Angenot, L., Bero, J., Tits, M., Ollivier, E., & Frederich, M. (2013). Dimeric bisindole alkaloids from the stem bark of Strychnos nux-vomica L. Phytochemistry, 87, 157-163. doi:10.1016/j.phytochem.2012.11.002
Peer Reviewed verified by ORBi

Denooz, R., Frederich, M., Charlier, C., & De Tullio, P. (2013). Application de la résonance magnétique nucléaire (RMN) en toxicologie judiciaire. Acta Clinica Belgica, 68 (6), 470.
Peer Reviewed verified by ORBi

bournine, L., Bensalem, S., Wauters, J.-N., Iguer-Ouada, M., Maiza-Benabdesselam, F., Bedjou, F., Castronovo, V., Bellahcene, A., Tits, M., & Frederich, M. (2013). Identification and Quantification of the Main Active Anticancer Alkaloids from the Root of Glaucium flavum. International Journal of Molecular Sciences, 14, 23533-23544. doi:10.3390/ijms141223533
Peer Reviewed verified by ORBi

Bero, J., Herent, M.-F., Schmeda-Hirschmann, G., Frederich, M., & Quetin-Leclercq, J. (2013). In vivo antimalarial activity of Keetia leucantha twigs extracts and in vitro antiplasmodial effect of their constituents. Journal of Ethnopharmacology, 149 (1), 176-83. doi:10.1016/j.jep.2013.06.018
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Mouton, J., Jansen, O., Frederich, M., & van der Kooy, F. (2013). Is artemisinin the only antiplasmodial compound in the Artemisia annua tea infusion? An in vitro study. Planta Medica, 79 (6), 468-70. doi:10.1055/s-0032-1328324
Peer Reviewed verified by ORBi

Mangwala Kimpende, P., Lusakibanza, M., Mesia, K., Tona, L., Tits, M., Angenot, L., Frederich, M., & Van Meervelt, L. (2013). Isolation, pharmacological activity and structure determination of physalin B and 5[beta],6[beta]-ep­oxy­physalin B isolated from Congolese Physalis angulata L. Acta Crystallographica. Section C, Structural Chemistry, C69, 1557-1562. doi:10.1107/S010827011303117X
Peer Reviewed verified by ORBi

Bournine, L., Bensalem, S., Peixoto, P., Gonzalez, A., Maiza-Benabdesselam, F., Bedjou, F., Wauters, J.-N., Tits, M., Frederich, M., Castronovo, V., & Bellahcene, A. (2013). Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine, 20 (13), 1211-1218. doi:10.1016/j.phymed.2013.06.007
Peer Reviewed verified by ORBi

Leverrier, A., Bero, J., Frederich, M., Quetin-Leclercq, J., & Palermo, J. (2013). Antiparasitic hybrids of Cinchona alkaloids and bile acids. European Journal of Medicinal Chemistry, 66, 355-63. doi:10.1016/j.ejmech.2013.06.004
Peer Reviewed verified by ORBi

Paltinean, R., Toju, A., Wauters, J.-N., Frederich, M., Tits, M., Angenot, L., Tamas, M., & Crisan, G. (2013). Identification and determination of alkaloids in Fumaria Species from Romania. Digest Journal of Nanomaterials and Biostructures, 8 (2), 817-824.
Peer Reviewed verified by ORBi

Paltinean, R., Wauters, J.-N., Tits, M., Frederich, M., Angenot, L., Mircea, T., & Crisan, G. (2013). Comparative morphological studies on some species of the genus Fumaria. Farmacia, 61 (2), 371-377.
Peer reviewed

Harnafi, H., Ramchoun, M., Tits, M., Wauters, J.-N., Frederich, M., Angenot, L., Aziz, M., Alem, C., & Amrani, S. (2013). Phenolic acid-rich extract of sweet basil restores cholesterol and triglycerides metabolism in high fat diet-fed mice: A comparison with fenofibrate. Biomedicine and Preventive Nutrition, 3 (4), 393-397. doi:10.1016/j.bionut.2013.03.005
Peer Reviewed verified by ORBi

Frederich, M., Jonville, M.-C., Grondin, I., & Kodja, H. (06 November 2012). Plantes Médicinales Antipaludiques de l'île de la Réunion. Paper presented at 7e CIPAM - Plantes médicinales aromatiques et médicinales, Saint Denis de la Réunion, France.

Jonville, M., Angenot, L., Tits, M., & Frederich, M. (August 2012). Bisindolomonoterpenic alkaloids from the stem bark of Strychnos nux-vomica exhibiting antiplasmodial activity. Planta Medica, 78 (11), 1047.
Peer Reviewed verified by ORBi

Béro, J., Frederich, M., & Quetin-Leclercq, J. (August 2012). In vivo antimalarial activity of twigs extracts from Keetia leucantha. Planta Medica, 78 (11), 1188.
Peer Reviewed verified by ORBi

Cieckiewicz, E., Angenot, L., Gras, T., Kiss, R., & Frederich, M. (August 2012). Potential anticancer activity of young Carpinus betulus leaves. Planta Medica, 78 (11), 1178. doi:10.1055/s-0032-1320840
Peer Reviewed verified by ORBi

Frederich, M. (05 July 2012). Investigation of African plants traditionally used to treat malaria. Paper presented at Colloque international sur l'analyse des médicaments et des toxiques et sur les plantes utilisées en Médecine Traditionnelle, Butare, Rwanda.

Tshisekedi Tshibangu, P., Kalenda Dibungi T., P., Wauters, J.-N., Tits, M., Frederich, M., Rozet, E., Hubert, P., & Marini Djang'Eing'A, R. (July 2012). DEVELOPMENT AND VALIDATION OF A LC-UV METHOD FOR THE DOSAGE OF A TRACER IN AN IMPROVED TRADITIONAL MEDICINE. Paper presented at Symposium sur les médicaments traditionnels antipaludiques et l’analyse des médicaments et des toxiques, Butare, Rwanda.

Frederich, M. (16 May 2012). Découverte de substances naturelles antipaludiques et métabolomique. Paper presented at Conférence à l'Université Médicale de Tbilissi, Tbilissi, Georgia.

Timmermans, C., De Tullio, P., Lambert, V., Frederich, M., Rousseau, R., & von Sachs, R. (2012). Advantages of the Bagidis methodology for metabonomics analyses: application to a spectroscopic study of Age-related Macular Degeneration. In Proceedings of the 12th European Symposium on Statistical Methods for the Food Industry.
Peer reviewed

Cieckiewicz, E., Angenot, L., Gras, T., Kiss, R., & Frederich, M. (15 February 2012). Potential anticancer activity of young Carpinus betulus leaves. Phytomedicine, 19 (3/4), 278-284. doi:10.1016/j.phymed.2011.09.072
Peer Reviewed verified by ORBi

Kalume, Losson, B., Angenot, L., Tits, M., Wauters, J.-N., Frederich, M., & Saegerman, C. (2012). Rotenoid content and in vitro acaricidal activity of Tephrosia vogelii leaf extract on the tick Rhipicephalus appendiculatus. Veterinary Parasitology, 190 (1-2), 204-209. doi:10.1016/j.vetpar.2012.06.015
Peer Reviewed verified by ORBi

Ndontsa, B., Tchinda Tiabou, A., Teponno, R., Mpetga, J., Frederich, M., & Tane, P. (2012). Ardisikivuoside, a new triterpenoid saponin from Ardisia kivuensis (Mysinaceae). Natural Product Communications, 7.
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Tamze, V., Ngono, A. R. N., Ayimele, G. A., Cao, M., Angenot, L., & Frederich, M. (2012). Alkaloids from the stem bark of Strychnos icaja. Phytochemistry Letters, 5 (1), 108-113. doi:10.1016/j.phytol.2011.11.004
Peer Reviewed verified by ORBi

Ganfon, Bero, J., Tchinda Tiabou, A., Gbaguidi, F., Gbenou, J., Moudachirou, M., Frederich, M., & Quetin-Leclercq", J. (2012). Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum D.C. Journal of Ethnopharmacology, 141 (0), 411-417. doi:10.1016/j.jep.2012.03.002
Peer Reviewed verified by ORBi

Jansen, O., Tits, M., Angenot, L., Nicolas, J.-P., De Mol, P., Nikiema, J.-B., & Frederich, M. (2012). Anti-plasmodial activity of Dicoma tomentosa (Asteraceae) and identification of urospermal A-15- O-acetate as the main active compound. Malaria Journal, 11 (1), 289 (1-9. doi:10.1186/1475-2875-11-289
Peer Reviewed verified by ORBi

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Crommen, J., & Fillet, M. (2012). Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic cyclodextrin derivatives and basic drug enantiomers in a methanolic background electrolyte. Journal of Chromatography. A, 1232, 59-64. doi:10.1016/j.chroma.2011.10.010
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Ngono, A. R., Tamze, V., Jonville, M., Cao, M., Angenot, L., & Frederich, M. (2012). Antiplasmodial Alkaloids from the Stem Bark of Strychnos malacoclados. Planta Medica, 78, 377-382. doi:10.1055/s-0031-1280473
Peer Reviewed verified by ORBi

Tsumbu, C. N., Dupont, G., Tits, M., Angenot, L., Frederich, M., Kohnen, S., Mouithys-Mickalad, A., Serteyn, D., & Franck, T. (2012). Polyphenol Content and Modulatory Activities of Some Tropical Dietary Plant Extracts on the Oxidant Activities of Neutrophils and Myeloperoxidase. International Journal of Molecular Sciences, 13 (1), 628-650. doi:10.3390/ijms13010628
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Zime Diawara, H., Dive, G., Piel, G., Moudachirou, M., Quetin-Leclercq, J., Frederich, M., & Evrard, B. (2012). UNDERSTANDING THE INTERACTIONS BETWEEN ARTEMISININ AND CYCLODEXTRINS: SPECTROSCOPIC STUDIES AND MOLECULAR MODELING. Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, 74 (1), 305-315. doi:10.1007/s10847-012-0117-9
Peer Reviewed verified by ORBi

Cao, M., Muganga, R., Nistor, I., Tits, M., Angenot, L., & Frederich, M. (2012). LC–SPE–NMR–MS analysis of Strychnos usambarensis fruits from Rwanda. Phytochemistry Letters, 5 (0), 170-173. doi:10.1016/j.phytol.2011.12.003
Peer Reviewed verified by ORBi

Wabo, H. K., Kowa, T. K., Lonfouo, A. H., Tchinda Tiabou, A., Tane, P., Kikuchi, H., Frederich, M., & Oshima, Y. (2012). Phenolic Compounds and Terpenoids from Hypericum lanceolatum. Records of Natural Products, 6 (2), 94-100.
Peer reviewed

Cao, M., Muganga, R., Tits, M., Angenot, L., & Frederich, M. (13 December 2011). 17-O-Actetyl-10-hydroxycorynantheol, a selective antiplasmodial alkaloid isolated from Strychnos usambarensis leaves. Paper presented at 50th Anniversary Meeting of Phytochemical Society of North America, Kohala Coast, United States - Hawaii.

Cao, M., Muganga, R., Tits, M., Angenot, L., & Frederich, M. (August 2011). 17-O-Acetyl,10-hydroxycorynantheol, a Selective Antiplasmodial Alkaloid Isolated from Strychnos usambarensis Leaves. Planta Medica, 77, 2050-2053. doi:10.1055/s-0031-1280124
Peer Reviewed verified by ORBi

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Crommen, J., & Fillet, M. (June 2011). Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic CD derivatives and basic drug enantiomers in a methanolic background electrolyte. Poster session presented at 36th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2011), Budapest, Hungary.

Frederich, M. (18 May 2011). Introduction à la métabolomique. Paper presented at Second Belgian Symposium on Metabolomics and Metabonomics, Liège, Belgium.

Cao, M., Muganga, R., Tits, M., Angenot, L., & Frederich, M. (13 May 2011). 17-O-acetyl, 10-hydroxycorynantheol, a selective antiplasmodial alkaloid isolated from Strychnos usambarensis leaves. Paper presented at 15th Forum of Pharmaceutical Sciences, Spa, Belgium.

Ziemons, E., Frederich, M., Fillet, M., Hubert, P., & Quetin-Leclercq, J. (May 2011). Espectroscopia aplicada. Paper presented at Maestra en Ciencia y Tecnologia de Productos Naturales, Cochabamba, Bolivia.

Servais, A.-C., Rousseau, A., Dive, G., Frederich, M., Pirotte, B., Crommen, J., & Fillet, M. (23 March 2011). Systèmes génériques pour la séparation d’énantiomères de molécules basiques et acides à l’aide de cyclodextrines en électrophorèse capillaire en milieu non aqueux. Paper presented at 9ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP 11), Toulouse, France.

Frederich, M., Tits, M., & Angenot, L. (2011). Pharmacognosie volume III. (Les éditions de l'Université de Liège, PHAR0332-1 Pharmacognosie (Partim II)).

Frederich, M., Wauters, J.-N., Tits, M., Jason, C., De Tullio, P., Van der Heyden, Y., Fan, G., & Angenot, L. (2011). Quality Assessment of Polygonum cuspidatum and Polygonum multiflorum by 1H NMR Metabolite Fingerprinting and Profiling Analysis. Planta Medica, 77, 81-86. doi:10.1055/s-0030-1250132
Peer Reviewed verified by ORBi

Tistaert, C., Thierry, L., Szandrach, A., Dejaegher, B., Fan, G., Frederich, M., & Vander Heyden, Y. (2011). Quality control of Citri reticulatae pericarpium: Exploratory analysis and discrimination. Analytica Chimica Acta, 705 (1-2), 111-22. doi:10.1016/j.aca.2011.04.024
Peer Reviewed verified by ORBi

Jonville, M., Kodja, H., Strasberg, D., Pichette, A., Ollivier, E., Frederich, M., Angenot, L., & Legault, J. (2011). Antiplasmodial, anti-inflammatory and cytotoxic activities of various plant extracts from the Mascarene Archipelago. Journal of Ethnopharmacology, 136, 525-531. doi:10.1016/j.jep.2010.06.013
Peer Reviewed verified by ORBi

Nistor, I., Cao, M., Debrus, B., Lebrun, P., Lecomte, F., Rozet, E., Angenot, L., Frederich, M., Oprean, R., & Hubert, P. (2011). Application of a new optimization strategy for the separation of tertiary alkaloids extracted from Strychnos usambarensis leaves. Journal of Pharmaceutical and Biomedical Analysis, 56, 30-37. doi:10.1016/j.jpba.2011.04.027
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (2011). Pharmacognosie volume II. (Les éditions de l'Université de Liège, PHAR0332-1 Pharmacognosie (Partim II)).

Melilo de Magalhaes, P., Schneider, Y. J., Dupont, I., Frederich, M., & Jonville, M. (03 October 2010). New strategy to in vitro evaluation of antimalarial drugs demonstre advantage of Artemisia annua crude extract on antimalarial effect by its tools to cross intestinal barrier.

Cao, M., Tits, M., Muganga, R., Angenot, L., & Frederich, M. (September 2010). LC-SPE-NMR-MS analysis of Strychnos usambarensis fruits from Rwanda. Planta Medica, 76 (12), 1241-1242.
Peer Reviewed verified by ORBi

Nistor, I., Debrus, B., Lebrun, P., Cao, M., Frederich, M., Angenot, L., Oprean, R., & Hubert, P. (September 2010). Application of experimental design and design space for the separation of compounds extracted from the leaves of Strychnos usambarensis. Paper presented at Drug Analysis 2010, Antwerpen, Belgium.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (September 2010). Application of experimental design and design for the separation of compounds extracted from the leaves of Strychnos Usambarensis. Poster session presented at Drug analysis 2010, Antwerpen, Belgium.

Jonville, M., Baghdikian, B., Ollivier, E., Angenot, L., Frederich, M., & Legault, J. (September 2010). Anti-inflammatory potency of the traditionally used antimalarial plant Fagraea fragrans. Planta Medica, 76 (12), 1171.
Peer Reviewed verified by ORBi

Tchinda Tiabou, A., Tamze, V., Frederich, M., & Angenot, L. (September 2010). Bioassay-guided isolation of antiplasmodial Strychnos alkaloids from the stem-bark of Strychnos icaja BAILLON. Planta Medica, 76 (12), 1305.
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (2010). Pharmacognosie volume I. (PHAR0331-2 Pharmacognosie (Partim I)). Liège, Belgium: Editions de l'Université de Liège.

Frederich, M. (07 July 2010). Sélection par ethnopharmacologie de plantes à potentialités antipaludéennes au Congo, Rwanda, Burkina-Faso et sur l'île de la Réunion. Paper presented at Colloque international sur les plantes antipaludiques utilisés en Médecine Traditionnelle, Abomey-Calavi, Benin.

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Martine, C., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (26 January 2010). Optimisation de la séparation des alcaloïdes extraits des feuilles de Strychnos usambarensis au moyen du design space. Paper presented at Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium.

Lusakibanza, M., Mesia, G., Tona, G., Karemere, S., Lukuka, A., Tits, M., Angenot, L., & Frederich, M. (2010). In vitro and in vivo antimalarial and cytotoxic activity of five plants used in Congolese traditional medicine. Journal of Ethnopharmacology, 129, 398-402. doi:10.1016/j.jep.2010.04.007
Peer Reviewed verified by ORBi

Liu, N. Q., Cao, M., Frederich, M., Choi, Y. H., Verpoorte, R., & van der Kooy, F. (2010). Metabolomic investigation of the ethnopharmacological use of Artemisia afra with NMR Spectroscopy and Multivariate Data Analysis. Journal of Ethnopharmacology, 128, 230-235. doi:10.1016/j.jep.2010.01.020
Peer Reviewed verified by ORBi

Gillotin, F., Chiap, P., Frederich, M., Van Heugen, J.-C., Francotte, P., Lebrun, P., Pirotte, B., & De Tullio, P. (2010). Coupling of Liquid Chromatography/Tandem Mass Spectrometry and Liquid Chromatography/Solid-Phase Extraction/NMR Techniques for the Structural Identification of Metabolites following In Vitro Biotransformation of SUR1-Selective ATP-Sensitive Potassium Channel Openers. Drug Metabolism and Disposition: the Biological Fate of Chemicals, 38 (2), 232-240. doi:10.1124/dmd.109.028928
Peer Reviewed verified by ORBi

Angenot, L., Tits, M., & Frederich, M. (2010). Pharmacognosie - Volume 2. (ULiège - Université de Liège, PHAR0332-1). Liège, Belgium: Les éditions de l'Université de Liège.

Angenot, L., Tits, M., & Frederich, M. (2010). Pharmacognosie Volume 3. (ULiège - Université de Liège, PHAR0332-1). Liège, Belgium: ULg - Université de Liège.

Jansen, O., Angenot, L., Tits, M., Nicolas, J. P., De Mol, P., Nikiéma, J. B., & Frederich, M. (2010). Evaluation of 13 selected medicinal plants from Burkina Faso for their antiplasmodial properties. Journal of Ethnopharmacology, 130, 143-150. doi:10.1016/j.jep.2010.04.032
Peer Reviewed verified by ORBi

Castagne, D., Dive, G., Evrard, B., Frederich, M., & Piel, G. (2010). Spectroscopic studies and molecular modeling for understanding the interactions between cholesterol and cyclodextrins. Journal of Pharmacy and Pharmaceutical Sciences, 13 (2), 362-377. doi:10.18433/j3bs34
Peer Reviewed verified by ORBi

Muganga, R., Angenot, L., Tits, M., & Frederich, M. (2010). Antiplasmodial and cytotoxic activities of Rwandan medicinal plants used in the treatment of malaria. Journal of Ethnopharmacology, 128, 52-55. doi:10.1016/j.jep.2009.12.023
Peer Reviewed verified by ORBi

Frederich, M., Jansen, C., De Tullio, P., Tits, M., Demoulin, V., & Angenot, L. (2010). Metabolomic analysis of Echinacea spp. by (1)H nuclear magnetic resonance spectrometry and multivariate data analysis technique. Phytochemical Analysis, 21 (1), 61-65. doi:10.1002/pca.1156
Peer Reviewed verified by ORBi

Ranghoo-Sanmukhiya, M., Govinden-Soulange, J., Lavergne, C., Khoyratty, S., Da Silva, D., Frederich, M., & Kodja, H. (2010). Molecular biology, phytochemistry and bioactivity of three endemic Aloe species from Mauritius and Reunion Islands. Phytochemical Analysis. doi:10.1002/pca.1234
Peer Reviewed verified by ORBi

Verpoorte, R., Frederich, M., Delaude, C., Angenot, L., Dive, G., Thépenier, P., Jacquier, M.-J., Zèches-Hanrot, M., Lavaud, C., & Nuzillard, J.-M. (2010). Moandaensine, a dimeric indole alkaloid from Strychnos moandaensis (Loganiaceae). Phytochemistry Letters, 3, 100-103. doi:10.1016/j.phytol.2010.02.005
Peer Reviewed verified by ORBi

Balde, E.-H. S., Mégalizzi, V., Angenot, L., Cao, M., Kiss, R., Van Damme, M., & Frederich, M. (2010). Isostrychnopentamine, an Indolomonoterpenic Alkaloid from Strychnos usambarensis, with Potential Antitumor Activity against Apoptosis-Resistant Cancer Cells. International Journal of Oncology, 36, 961-965. doi:10.3892/ijo_00000575
Peer Reviewed verified by ORBi

Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (December 2009). Application de la planification expérimentale et du design space pour la séparation des composés extraits des feuilles de Strychnos usambarensis. Poster session presented at 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France.

Frederich, M. (08 October 2009). A la découverte de médicaments d'origine naturelle pour lutter contre le paludisme.

Jansen, O., Nikiéma, J.-B., Angenot, L., Tits, M., Nicolas, J.-P., De Mol, P., & Frederich, M. (07 October 2009). Evaluation des potentialités antiplasmodiales de plantes utilisées en médecine traditionnelle au Burkina Faso. Paper presented at 2eme rencontre Internationale de Phytothérapie de Ouagadougou, Ouagadougou, Burkina Faso.

Castagne, D., Frederich, M., Evrard, B., Nusgens, B., Dive, G., & Piel, G. (June 2009). Studies for understanding the interactions between biological membranes and cyclodextrins and their effects at the cell level. Poster session presented at 2nd PharmSciFair, Nice, France.

Ouattara, B., Jansen, O., Angenot, L., Guissou, P., Frederich, M., Fondu, P., & Tits, M. (March 2009). Antisickling properties of divanilloylquinic acids isolated from Fagara zanthoxyloides Lam. (Rutaceae). Phytomedicine, 16 (2-3), 125-129. doi:10.1016/j.phymed.2008.10.013
Peer Reviewed verified by ORBi

Frederich, M. (28 January 2009). Métabolomique - Identification de métabolites (biomarqueurs) par RMN 2D et LC-NMR. Paper presented at 1ères Journées de Métabolomique, Mons, Belgium.

Frederich, M. (27 January 2009). A la découverte de médicaments d'origine naturelle pour lutter contre le paludisme.

Murebwayire, S., Ingkaninan, K., Changwijit, K., Frederich, M., & Duez, P. (2009). Triclisia sacleuxii (Pierre) Diels (Menispermaceae), a potential source of acetylcholinesterase inhibitors. Journal of Pharmacy and Pharmacology, 61 (1), 103-7. doi:10.1211/jpp/61.01.0014
Peer Reviewed verified by ORBi

Frederich, M., Delvaux, D., Gigliobianco, T., GANGOLF, M., Dive, G., Mazzucchelli, G., Elias, B., De Pauw, E., Angenot, L., Wins, P., & Bettendorff, L. (2009). Thiaminylated adenine nucleotides — chemical synthesis, structural characterization and natural occurrence. FEBS Journal, 276 (12), 3256–3268. doi:10.1111/j.1742-4658.2009.07040.x
Peer Reviewed verified by ORBi

Bero, J., Ganfon, H., Jonville, M., Frederich, M., Gbaguidi, F., De Mol, P., Moudachirou, M., & Quetin-Leclercq, J. (2009). In vitro antiplasmodial activity of plants used in Benin in traditional medicine to treat malaria. Journal of Ethnopharmacology, 122, 439-444. doi:10.1016/j.jep.2009.02.004
Peer Reviewed verified by ORBi

Frederich, M., Marcowycz, A., Cieckiewicz, E., Megalizzi, V., Angenot, L., & Kiss, R. (2009). In Vitro Anticancer Potential of Tree Extracts from the Walloon Region Forest. Planta Medica, 75 (15), 1634-1637. doi:10.1055/s-0029-1185867
Peer Reviewed verified by ORBi

Bero, J., Frederich, M., & Quetin-Leclercq, J. (2009). Antimalarial compounds isolated from plants used in traditional medicine. Journal of Pharmacy and Pharmacology, 61 (11), 1401-33. doi:10.1211/jpp.61.11.0001
Peer Reviewed verified by ORBi

Karangwa, C., Esters, V., Frederich, M., Tits, M., Kadima, J. N., Damas, J., Noirfalise, A., & Angenot, L. (2009). Erratum to “Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp. montana” [J. Ethnopharmacol. 103 (2006) 433–438]. Journal of Ethnopharmacology, 125, 503. doi:10.1016/j.jep.2009.06.035
Peer Reviewed verified by ORBi

Castagne, D., Frederich, M., Dive, G., Evrard, B., & Piel, G. (November 2008). Etude par modélisation moléculaire et spectroscopie RMN des interactions entre le cholestérol et les cyclodextrines afin de comprendre leurs effets sur les membranes cellulaires. Paper presented at 11èmes Journées du Club français des Cyclodextrines, Rouen, France.

Jonville, M., Capel, M., Frederich, M., Angenot, L., Dive, G., Faure, R., Azas, N., & Ollivier, E. (November 2008). Fagraldehyde, a Secoiridoid Isolated from Fagraea fragrans. Journal of Natural Products, 71 (12), 2038-2040. doi:10.1021/np800291d
Peer Reviewed verified by ORBi

Lambert, V., Frederich, M., Rousseau, R., Detry, B., Peulen, O., Rakic, J.-M., Noël, A., Pirotte, B., Govaert, B., & De Tullio, P. (August 2008). 1H NMR metabolomic approach of the laser-induced choroidal neovascularization in mice. Poster session presented at 20th International Symposium on Medicinal Chemistry, Vienne, Austria.

Jansen, O., Frederich, M., Tits, M., Angenot, L., Cousineau, S., Bessot, L., Crunet, C., & Nicolas, J.-P. (July 2008). Ethnopharmacologie et paludisme au Burkina Faso : sélection de 13 espèces à potentialités antiplasmodiales méconnues. Ethnopharmacologia, 41, 74-81.
Peer reviewed

Frederich, M. (19 June 2008). A la recherche de substances naturelles à potentialités antiplasmodiales et cytotoxiques.

Barillaro, V., Dive, G., Bertholet, P., Evrard, B., Delattre, L., Frederich, M., Ziemons, E., & Piel, G. (22 January 2008). Theoretical and Experimental Investigations of Organic Acids/Cyclodextrin Complexes and Their Consequences Upon the Formation of Miconazole/Cyclodextrin/Acid Ternary Inclusion Complexes. International Journal of Pharmaceutics, 347 (1-2), 62-70. doi:10.1016/j.ijpharm.2007.06.030
Peer Reviewed verified by ORBi

Jonville, M., Kodja, H., Humeau, L., Fournel, J., De Mol, P., Cao, M., Angenot, L., & Frederich, M. (2008). Screening of medicinal plants from Reunion Island for antimalarial and cytotoxic activity. Journal of Ethnopharmacology, 120 (3), 382-6. doi:10.1016/j.jep.2008.09.005
Peer Reviewed verified by ORBi

Murebwayire, S., Frederich, M., Hannaert, V., Jonville, M., & Duez, P. (2008). Antiplasmodial and antitrypanosomal activity of Triclisia sacleuxii (Pierre) Diels. Phytomedicine, 15 (9), 728-733. doi:10.1016/j.phymed.2007.10.005
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (January 2008). Potential antimalarial activity of indole alkaloids. Transactions of the Royal Society of Tropical Medicine and Hygiene, 102 (1), 11-19. doi:10.1016/j.trstmh.2007.10.002
Peer Reviewed verified by ORBi

Bero, J., Frederich, M., De Mol, P., & Quetin-Leclercq, J. (2008). In vitro antiplasmodial activity of five plants used in Benin in traditional medicine to treat malaria. Planta Medica, 74 (9), 1002-1002.
Peer Reviewed verified by ORBi

Ganfon, H., Gbaguidi, F., Frederich, M., Moudachirou, M., & Quetin-Leclercq, J. (2008). In vitro evaluation of antiplasmodial activity of plant samples used in traditional medicine in Benin. Planta Medica, 74 (9), 1140-1140.
Peer Reviewed verified by ORBi

Jansen, O., Angenot, L., Tits, M., Nicolas, J.-P., De Mol, P., Sacré, P.-Y., Jonville, M., & Frederich, M. (2008). In vitro antiplasmodial activity of ethnobotanically selected plants from Burkina Faso. Planta Medica, 74 (9), 1142-1142.
Peer Reviewed verified by ORBi

Jonville, M., Kodja, H., Humeau, L., Fournel, J., Chariot, A., De Mol, P., Cao, M.-C., Angenot, L., & Frederich, M. (2008). Evaluation of medicinal plants from Reunion Island for antimalarial and cytotoxic activities. Planta Medica, 74 (9), 1002-1002.
Peer Reviewed verified by ORBi

Frederich, M., Jansen, C., De Tullio, P., Demoulin, V., Tits, M., & Angenot, L. (2008). Metabolomic analysis of Echinacea sp. by H-1 Nuclear magnetic resonance spectrometry and multivariate analysis techniques. Planta Medica, 74 (9), 1089-1089.
Peer Reviewed verified by ORBi

Frederich, M. (10 December 2007). A la recherche de substances naturelles antiplasmodiales et cytotoxiques. Paper presented at Séminaires des Sciences Pharmaceutiques de l'UCL, Louvain la Neuve, Belgium.

Francotte, P., Gillotin, F., Van Heuguen, J. C., Frederich, M., Lebrun, P., CHIAP, P., Pirotte, B., & De Tullio, P. (October 2007). Application of LC-SPE-NMR to the structural determination of metabolites of KATP channel openers belonging to 3-alkylamino-4H-1,2,4-arylthiadiazine 1,1-dioxides. Paper presented at 13th Forum of Pharmaceutical Sciences, Spa, Belgium.

Jokhadze, M., Eristavi, L., Kutchukhidze, J., Chariot, A., Angenot, L., Tits, M., Jansen, O., & Frederich, M. (July 2007). In vitro cytotoxicity of some medicinal plants from Georgian amaryllidaceae. Phytotherapy Research, 21 (7), 622-624. doi:10.1002/ptr.2130
Peer Reviewed verified by ORBi

Frederich, M. (2007). Contribution à l'étude de substances naturelles à potentialités antiplasmodiales et cytotoxiques. Isolement, détermination de structure par résonance magnétique nucléaire à haut champ et évaluation pharmacologique. Unpublished post doctoral thesis (Agrégation de l'enseignement supérieur), ULiège - Université de Liège.
Jury: Angenot, L. (Promotor).

Philippe, G., De Mol, P., Angenot, L., Tits, M., & Frederich, M. (May 2007). In vivo antimalarial activity of isosungucine, an indolomonoterpenic alkaloid from Strychnos icaja. Planta Medica, 73 (5), 478-479. doi:10.1055/s-2007-967174
Peer Reviewed verified by ORBi

Ziemons, E., Dive, G., Debrus, B., Barillaro, V., Frederich, M., Lejeune, R., Angenot, L., Delattre, L., Thunus, L., & Hubert, P. (February 2007). Study of the physicochemical properties in aqueous medium and molecular modeling of tagitinin C/cyclodextrin complexes. Journal of Pharmaceutical and Biomedical Analysis, 43 (3), 910-919. doi:10.1016/j.jpba.2006.09.011
Peer Reviewed verified by ORBi

Gillotin, F., De Tullio, P., VAN HEUGEN, J.-C., Francotte, P., Frederich, M., Lebrun, P., Kremers, P., Pirotte, B., & CHIAP, P. (2007). Coupling of the LC-MS/MS and the LC-SPE-NMR for the structural identification of pancreatic KATP channel openers metabolites following in vitro biotransformation. Poster session presented at HPLC 2007, Gent, Belgium.

Bettendorff, L., Wirtzfeld, B., Makarchikov, A. F., Mazzucchelli, G., Frederich, M., Gigliobianco, T., Gangolf, M., De Pauw, E., Angenot, L., & Wins, P. (2007). Discovery of a natural thiamine adenine nucleotide. Nature Chemical Biology, 3 (4), 211-212. doi:10.1038/nchembio867
Peer Reviewed verified by ORBi

Gnoula, C., Guissou, P., Duez, P., Frederich, M., & Dubois, J. (2007). Nematocidal compounds from the seeds of Balanites aegyptiaca isolation and structure elucidation. International Journal of Pharmacology, 3 (3), 280-284. doi:10.3923/ijp.2007.280.284
Peer Reviewed verified by ORBi

Frederich, M., Philippe, G., Tits, M., & Angenot, L. (2007). Potentialités antipaludiques des alcaloïdes indoliques. Actualités de Chimie Thérapeutique, 33, 1-32.

De Tullio, P., Chiap, P., Francotte, P., Van Heugen, J.-C., Florence, X., Frederich, M., Gillotin, F., Kremers, P., Lebrun, P., & Pirotte, B. (18 November 2006). In vitro metabolisation study of several 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers : combined use of LC-Q-TOF MS/MS and LC-SPE-NMR. Poster session presented at Réunion de la Société Belge de Physiologie et de Pharmacologie Fondamentales et Cliniques, Bruxelles, Belgium.

De Tullio, P., Frederich, M., Chiap, P., Kremers, P., Francotte, P., Lebrun, P., & Pirotte, B. (17 November 2006). Application of LC-SPE-NMR to the structural determination of KATP channel openers metabolites belonging to the 3-alkylamino-4H-1,2,4-arylthiadiazine 1,1-dioxide derivatives. Paper presented at 5th YBMRS, Bruxelles, Belgium.

De Tullio, P., Gillotin, F., Francotte, P., Van Heugen, J.-C., Frederich, M., Lebrun, P., Chiap, P., & Pirotte, B. (August 2006). Combined use of LC-SPE-NMR and LC-MS for the metabolites characterization of ATP-sensitive potassium channel openers belonging to 3-alkylamino-4H-1,2,4-arylthiadiazine 1,1-dioxides. Poster session presented at XIXth International Symposium on Medicinal Chemistry, Istanbul, Turkey.

De Tullio, P., Chiap, P., Francotte, P., Van Heugen, J.-C., Florence, X., Frederich, M., Gillotin, F., Kremers, P., Lebrun, P., & Pirotte, B. (June 2006). Application de la LC-SPE-RMN et de la LC-MS à la détermination structurale des métabolites d’activateurs des canaux KATP de la classe des 3-alkylamino-4H-arylthiadiazine 1,1-dioxydes. Poster session presented at 20èmes Journées Franco-Belges de Pharmacochimie, Lille, France.

Gillotin, F., De Tullio, P., Van Heugen, J.-C., Francotte, P., Frederich, M., Lebrun, P., Kremers, P., Chiap, P., & Pirotte, B. (17 May 2006). Application of LC-SPE-NMR and LC-Q-TOF MS/MS to the structural determination of KATP channel openers metabolites belonging to the 3-alkylamino-4H-1,2,4-arylthiadiazine 1,1-dioxides. Poster session presented at 10th Bioforum, Liège, Belgium.

Frederich, M. (16 May 2006). Structure elucidation of secondary metabolites in crude extracts by 2D-NMR and LC-NMR. Paper presented at Drug Analysis, Namur, Belgium.

Jansen, O., Akhmedjanova, V., Angenot, L., Balansard, G., Chariot, A., Ollivier, E., Tits, M., & Frederich, M. (21 April 2006). Screening of 14 alkaloids isolated from Haplophyllum A. Juss. for their cytotoxic properties. Journal of Ethnopharmacology, 105 (1-2), 241-245. doi:10.1016/j.jep.2005.11.001
Peer Reviewed verified by ORBi

Esters, V., Angenot, L., Brandt, V., Frederich, M., Tits, M., Van Nerum, C., Wauters, J.-N., & Hubert, P. (21 April 2006). Validation of a high-performance thin-layer chromatography/densitometry method for the quantitative determination of glucosamine in a herbal dietary supplement. Journal of Chromatography. A, 1112 (1-2), 156-164. doi:10.1016/j.chroma.2006.01.035
Peer Reviewed verified by ORBi

Frederich, M. (07 April 2006). Application of NMR to Identification of Metabolites. Paper presented at Metabolomics courses, Leiden, Netherlands.

Kenmogne, M., Prost, E., Harakat, D., Jacquier, M.-J., Frederich, M., Sondengam, L. B., Zèches, M., & Waffo-Téguo, P. (March 2006). Five labdane diterpenoids from the seeds of Aframomum zambesiacum. Phytochemistry, 67 (5), 433-438. doi:10.1016/j.phytochem.2005.10.015
Peer Reviewed verified by ORBi

Karangwa, C., Esters, V., Frederich, M., Tits, M., Kadima, J. N., Damas, J., Noirfalise, A., & Angenot, L. (February 2006). Chemical and biological investigations of a toxic plant from Central Africa, Magnistipula butayei subsp montana. Journal of Ethnopharmacology, 103 (3), 433-438. doi:10.1016/j.jep.2005.08.019
Peer Reviewed verified by ORBi

Philippe, G., Nguyen, L., Angenot, L., Frederich, M., Moonen, G., Tits, M., & Rigo, J.-M. (13 January 2006). Study of the interaction of antiplasmodial strychnine derivatives with the glycine receptor. European Journal of Pharmacology, 530 (1-2), 15-22. doi:10.1016/j.ejphar.2005.11.048
Peer Reviewed verified by ORBi

Jokhadze, M., Kutchukhidze, J., Murtazashvilia, T., Frederich, M., & Angenot, L. (2006). Extraction and fractionation of cytotoxic metabolites from Galanthus lagodechianus Kem.-Nath. Allergology and Immunology (Moscou), 7, 649-650.
Peer reviewed

Otshudi, A. L., Apers, S., Pieters, L., Claeys, M., Pannecouque, C., De Clercq, E., Van Zeebroeck, A., Lauwers, S., Frederich, M., & Foriers, A. (31 October 2005). Biologically active bisbenzylisoquinoline alkaloids from the root bark of Epinetrum villosum. Journal of Ethnopharmacology, 102 (1), 89-94. doi:10.1016/j.jep.2005.05.021
Peer Reviewed verified by ORBi

Frederich, M. (22 August 2005). Metabolomic analysis of Strychnos species extracts by 1 H nuclear magnetic resonance spectrometry and multivariate analysis techniques. Paper presented at 53rd annual congress from the Society for Medicinal Plant Research, Florence, Italy.

Frederich, M. (13 June 2005). Metabolomic analysis of Strychnos species extracts by 1 H nuclear magnetic resonance spectrometry and multivariate analysis techniques. Paper presented at Pharmscifair 2005, Nice, France.

Philippe, G., Angenot, L., De Mol, P., Goffin, E., Hayette, M.-P., Tits, M., & Frederich, M. (21 March 2005). In vitro screening of some Strychnos species for antiplasmodial activity. Journal of Ethnopharmacology, 97 (3), 535-539. doi:10.1016/j.jep.2004.12.011
Peer Reviewed verified by ORBi

Philippe, G., Angenot, L., Tits, M., & Frederich, M. (15 September 2004). About the toxicity of some Strychnos species and their alkaloids. Toxicon, 44 (4), 405-416. doi:10.1016/j.toxicon.2004.05.006
Peer Reviewed verified by ORBi

Frederich, M., Choi, Y. H., Angenot, L., Harnischfeger, G., Lefeber, A. W. M., & Verpoorte, R. (July 2004). Metabolomic analysis of Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extracts by H-1 nuclear magnetic resonance spectrometry and multivariate analysis techniques. Phytochemistry, 65 (13), 1993-2001. doi:10.1016/j.phytochem.2004.06.015
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., Goffin, E., Philippe, G., Grellier, P., De Mol, P., Hayette, M.-P., & Angenot, L. (June 2004). In vitro and in vivo antimalarial properties of isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis. Planta Medica, 70 (6), 520-525. doi:10.1055/s-2004-827151
Peer Reviewed verified by ORBi

Ouattara, B., Angenot, L., Guissou, P., Fondu, P., Dubois, J., Frederich, M., Jansen, O., Van Heugen, J.-C., Wauters, J.-N., & Tits, M. (April 2004). LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam. Phytochemistry, 65 (8), 1145-1151. doi:10.1016/j.phytochem.2004.02.025
Peer Reviewed verified by ORBi

De leval, X., Julémont, F., Benoit, V., Frederich, M., Pirotte, B., & Dogné, J.-M. (2004). First and second generations of COX-2 selective inhibitors. Mini Reviews in Medicinal Chemistry, 4, 597-601. doi:10.2174/1389557043403693
Peer Reviewed verified by ORBi

Choi, Y. H., Hazekamp, A., Peltenburg-Looman, A. M. G., Frederich, M., Erkelens, C., Lefeber, A. W. M., & Verpoorte, R. (2004). NMR assignments of the major Cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa. Phytochemical Analysis, 15 (6, NOV-DEC), 345-354. doi:10.1002/pca.787
Peer Reviewed verified by ORBi

Frederich, M., Cristino, A., Choi, Y. H., Verpoorte, R., Tits, M., Angenot, L., Prost, E., Nuzillard, J.-M., & Zèches-Hanrot, M. (January 2004). Chrysopentamine, an antiplasmodial anhydronium base from Strychnos usambarensis leaves. Planta Medica, 70 (1), 72-76. doi:10.1055/s-2004-815461
Peer Reviewed verified by ORBi

El-Sayed, M., Choi, Y. H., Frederich, M., Roytrakul, S., & Verpoorte, R. (2004). Alkaloid accumulation in Catharanthus roseus cell suspension cultures fed with stemmadenine. Biotechnology Letters, 26 (10), 793-798. doi:10.1023/B:BILE.0000025879.53632.f2
Peer Reviewed verified by ORBi

Dogné, J.-M., De leval, X., Hanson, J., Frederich, M., Lambermont, B., Ghuysen, A., Casini, A., Masereel, B., Ruan, K. E., Pirotte, B., & Kolh, P. (2004). New developments on thromboxane and prostacyclin modulators. Part I: thromboxane modulators. Current Medicinal Chemistry, 11, 1223-1241. doi:10.2174/0929867043365260
Peer Reviewed verified by ORBi

Frederich, M., Choi, Y. H., & Verpoorte, R. (December 2003). Quantitative analysis of strychnine and brucine in Strychnos nux-vomica using H-1-NMR. Planta Medica, 69 (12), 1169-1171. doi:10.1055/s-2003-818014
Peer Reviewed verified by ORBi

Goffin, E., da Cunha, A. P., Ziemons, E., Tits, M., Angenot, L., & Frederich, M. (November 2003). Quantification of tagitinin C in Tithonia diversifolia by reversed-phase high-performance liquid chromatography. Phytochemical Analysis, 14 (6), 378-80. doi:10.1002/pca.732
Peer Reviewed verified by ORBi

Frederich, M. (14 March 2003). Antiplasmodial and cytotoxic alkaloids from Strychnos species. Paper presented at 13th Symposium from the ALW-Discussion Group, "Secondary Metabolism in Plant and Plant Cell", Utrecht, Netherlands.

Frederich, M., Bentires-Alj, M., Tits, M., Angenot, L., Greimers, R., Gielen, J., Bours, V., & Merville, M.-P. (March 2003). Isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis, induces cell cycle arrest and apoptosis in human colon cancer cells. Journal of Pharmacology and Experimental Therapeutics, 304 (3), 1103-1110. doi:10.1124/jpet.102.044867
Peer Reviewed verified by ORBi

Frederich, M., Bentires-Ali, M., Tits, M., Angenot, L., Heinen, E., & De Pauw-Gillet, M.-C. (March 2003). Apoptosis induction in human cancer cells by sungucine from Strychnos icaja root. Naunyn-Schmiedeberg's Archives of Pharmacology, 367 (3), 260-265. doi:10.1007/s00210-003-0691-x
Peer Reviewed verified by ORBi

Philippe, G., Angenot, L., De Mol, P., Goffin, E., Tits, M., & Frederich, M. (February 2003). In vitro screening of Strychnos species for antiplasmodial activity. Poster session presented at 27th Landelijk Overleg Farmacognosie (LOF) Symposium, Antwerpen, Belgium.

Philippe, G., De Mol, P., Zeches-Hanrot, M., Nuzillard, J. M., Tits, M., Angenot, L., & Frederich, M. (February 2003). Indolomonoterpenic alkaloids from Strychnos icaja roots. Phytochemistry, 62 (4), 623-629. doi:10.1016/S0031-9422(02)00612-X
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (2003). Indole alkaloids from Strychnos species and their antiplasmodial and cytotoxic activities. Chemistry of Natural Compounds, 39 (6, NOV-DEC), 513-519. doi:10.1023/B:CONC.0000018100.67335.b5

Frederich, M., Philippe, G., Tits, M., & Angenot, L. (30 October 2002). Strychnohexamine from Strychnos icaja, the first naturally occurring indolomonoterpenic trimeric alkaloid. Poster session presented at First International Pharmaceutical Congress, Tbilisi, Georgia.

Angenot, L., Garbacki, N., Damas, J., Bassleer, C., Frederich, M., & Tits, M. (29 October 2002). Effects of prodelphinidins isolated from Ribes nigrum leaves on chondrocyte metabolism and COX activity. Poster session presented at First International Pharmaceutical Congress, Tbilisi, Georgia.

Frederich, M. (17 October 2002). Les substances naturelles dans la lutte contre le paludisme. Paper presented at Colloques du jeudi de la Fondation Léon Frédéricq, Liège, Belgium.

Frederich, M., Jacquier, M. J., Thepenier, P., De Mol, P., Tits, M., Philippe, G., Delaude, C., Angenot, L., & Zeches-Hanrot, M. (October 2002). Antiplasmodial activity of alkaloids from various Strychnos species. Journal of Natural Products, 65 (10), 1381-1386. doi:10.1021/np020070e
Peer Reviewed verified by ORBi

Gerkens, P., Frederich, M., Mshvildadze, V., Dekanosidze, G., Balansard, G., Elias, R., Angenot, L., Jolois, O., & De Pauw-Gillet, M.-C. (September 2002). Activités cytotoxiques et apoptotiques de gigantéosides D et E isolés de Cephalaria gigantea. Poster session presented at Journées AFERP, Athène, Greece.

Frederich, M., Philippe, G., Prost, E., Nuzillard, J.-M., Zèches-Hanrot, M., Tits, M., & Angenot, L. (September 2002). Strychnohexamine from Strychnos icaja; the first naturally occurring indolomonoterpenoid trimeric alkaloid. Poster session presented at 2èmes Journées Internationales de l'AFERP, Athènes, Greece.

Frederich, M., Dogné, J.-M., Angenot, L., & De Mol, P. (August 2002). New trends in anti-malarial agents. Current Medicinal Chemistry, 9 (15), 1435-1456. doi:10.2174/0929867023369691
Peer Reviewed verified by ORBi

Lansiaux, A., Bailly, C., Houssier, C., Colson, P., De Pauw-Gillet, M.-C., Frederich, M., Tits, M., & Angenot, L. (July 2002). Apoptosis of HL-60 leukemia cells induced by the bisindole alkaloids sungucine and isosungucine from Strychnos icaja. Planta Medica, 68 (7), 591-595. doi:10.1055/s-2002-32889
Peer Reviewed verified by ORBi

Goffin, E., Ziemons, E., De Mol, P., de Madureira, M. D. C., Martins, A. P., da Cunha, A. P., Philippe, G., Tits, M., Angenot, L., & Frederich, M. (June 2002). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its main active constituent: tagitinin C. Planta Medica, 68 (6), 543-5. doi:10.1055/s-2002-32552
Peer Reviewed verified by ORBi

Frederich, M. (31 May 2002). A la recherche d’alcaloïdes indolomonoterpéniques et autres substances naturelles à propriétés antiplasmodiales ou antitumorales. Paper presented at 16èmes Journées Franco-Belges de Pharmacochimie, "De la conception à la réalisation en Pharmacochimie", Caen, France.

Philippe, G., Prost, E., Nuzillard, J. M., Zeches-Hanrot, M., Tits, M., Angenot, L., & Frederich, M. (29 April 2002). Strychnohexamine from Strychnos icaja, a naturally occurring trimeric indolomonoterpenic alkaloid. Tetrahedron Letters, 43 (18), 3387-3390. doi:10.1016/S0040-4039(02)00476-8
Peer Reviewed verified by ORBi

Goffin, E., Garbacki, N., Damas, J., Tits, M., Angenot, L., & Frederich, M. (2002). Tagitinin C from Tithonia diversifolia : anti-inflammatory activity and high performance liquid chromatogaphic quantification. Poster session presented at 50th Annual Congress of the Society for Medicinal Plant Research, Barcelona, Spain.

Penelle, J., Christen, P., Molgo, J., Tits, M., Brandt, V., Frederich, M., & Angenot, L. (October 2001). 5',6'-Dehydroguiachrysine and 5',6'-Dehydroguiaflavine, Two Curarizing Quaternary Indole Alkaloids from the Stem Bark of Strychnos Guianensis. Phytochemistry, 58 (4), 619-26. doi:10.1016/S0031-9422(01)00255-2
Peer Reviewed verified by ORBi

Goffin, E., Frederich, M., Philippe, G., Ziemons, E., De Mol, P., Proença da Cunha, A., Tits, M., & Angenot, L. (September 2001). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its active constituent: tagitinin C. Poster session presented at Lead Compounds from Higher Plants, Lausanne, Switzerland.

Frederich, M., Tits, M., HAYETTE, M.-P., De Mol, P., & Angenot, L. (September 2001). Reversal of Chloroquine and Mefloquine Resistance in Plasmodium falciparum by two monoindole alkaloids; icajine and isoretuline. Poster session presented at Lead Compounds from Higher Plants, Lausanne, Switzerland.

Frederich, M., Hayette, M.-P., Tits, M., De Mol, P., & Angenot, L. (August 2001). Reversal of Chloroquine and Mefloquine Resistance in Plasmodium Falciparum by the Two Monoindole Alkaloids, Icajine and Isoretuline. Planta Medica, 67 (6), 523-7. doi:10.1055/s-2001-16476
Peer Reviewed verified by ORBi

Brandt, V., Tits, M., Penelle, J., Frederich, M., & Angenot, L. (July 2001). Main Glucosidase Conversion Products of the Gluco-Alkaloids Dolichantoside and Palicoside. Phytochemistry, 57 (5), 653-9. doi:10.1016/S0031-9422(01)00085-1
Peer Reviewed verified by ORBi

Frederich, M., De Pauw-Gillet, M.-C., Prosperi, C., Tits, M., Brandt, V., Penelle, J., Hayette, M.-P., De Mol, P., & Angenot, L. (January 2001). Strychnogucines a and B, Two New Antiplasmodial Bisindole Alkaloids from Strychnos Icaja. Journal of Natural Products, 64 (1), 12-16. doi:10.1021/np000285t
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., Penelle, J., Prosperi, C., HAYETTE, M.-P., De Mol, P., & Angenot, L. (September 2000). Strychnogucines A and B, two new antiplasmodial bisindole alkaloids from Strychnos icaja. Poster session presented at Natural Products Research in the new Millenium and Ethnopharmacology 2000, Zurich, Switzerland.

Penelle, J., Tits, M., Christen, P., Molgo, J., Frederich, M., & Angenot, L. (September 2000). Contribution to the study of Strychnos guianensis : purification and structural determination of potentially curarizing quaternary alkaloids. Poster session presented at Natural Products Research in the New Millenium and Ethnopharmacology 2000, Zurich, Switzerland.

De Pauw-Gillet, M.-C., Frederich, M., Tits, M., & Angenot, L. (July 2000). Etude du mécanisme d’action d’alcaloides bisindoliques, isolés du Strychnos icaja, à potentialité anticancéreuse. Poster session presented at Journées internationales de Pharmacognosie, Liege, Belgium.

Frederich, M., De Mol, P., & Angenot, L. (July 2000). A la recherche de nouveaux alcaloïdes antipaludiques à partir du genre Strychnos. Paper presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Penelle, J., Tits, M., Christen, P., Molgo, J., Brandt Viviane, Frederich, M., & Angenot, L. (July 2000). Contribution à l'étude du Strychnos guianensis : purification et détermination de structure d'alcaloïdes quaternaires potentiellement curarisants. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Tits, M., de Leval Xavier, Dierckxsens, Y., Garbacki, N., Brandt Viviane, Penelle, J., Frederich, M., Delarge Jacques, & Angenot, L. (July 2000). Antiinflammatory and chonroprotective activity of prodelphinidins isolated from Ribes nigrum leaves. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Cristino, A., Tits, M., Penelle, J., Frederich, M., Brandt Viviane, & Angenot, L. (July 2000). Nouvelle méthode d'extraction et d'isolement de l'isostrychnopentamine à partir des feuilles de Strychnos usambarensis. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Brandt, V., Tits, M., Penelle, J., Frederich, M., & Angenot, L. (July 2000). Palicoside: précurseur naturel de l'akagérine. Poster session presented at 1es Journées Internationales de Pharmacognosie, Liège, Belgium.

Penelle, J., Tits, M., Christen, P., Molgo, J., Brandt, V., Frederich, M., & Angenot, L. (April 2000). Quaternary Indole Alkaloids from the Stem Bark of Strychnos Guianensis. Phytochemistry, 53 (8), 1057-66. doi:10.1016/S0031-9422(00)00033-9
Peer Reviewed verified by ORBi

Frederich, M., De Pauw-Gillet, M.-C., Llabres, G., Tits, M., Hayette, M.-P., Brandt, V., Penelle, J., De Mol, P., & Angenot, L. (April 2000). New Antimalarial and Cytotoxic Sungucine Derivatives from Strychnos Icaja Roots. Planta Medica, 66 (3), 262-9. doi:10.1055/s-2000-8559
Peer Reviewed verified by ORBi

Frederich, M. (2000). ISOLEMENT ET DETERMINATION DE STRUCTURE D’ALCALOÏDES INDOLIQUES. ETUDE DE LEUR ACTIVITE SUR PLASMODIUM FALCIPARUM. Unpublished doctoral thesis, ULiège - Université de Liège.
Jury: Angenot, L. (Promotor).

Tits, M., de Leval, X., Diercksens, Y., Garbacki, N., Brandt, V., Penelle, J., Frederich, M., Delarge, J., & Angenot, L. (2000). Anti-inflammatory and chondroprotective activity of prodelphinidins isolated from Ribes nigrum leaves. Poster session presented at International Congress and 48th Annual Meeting of the Society for Medicinal Plant Research (GA), 6th International Congress on Ethnopharmacology of the International Society for Ethnopharmacology (ISE), Zürich, Switzerland.

Frederich, M., Hayette, M.-P., Tits, M., De Mol, P., & Angenot, L. (September 1999). In Vitro Activities of Strychnos Alkaloids and Extracts against Plasmodium Falciparum. Antimicrobial Agents and Chemotherapy, 43 (9), 2328-31. doi:10.1128/aac.43.9.2328
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., Hayette, M.-P., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (July 1999). 10'-hydroxyusambarensine, a new antimalarial bisindole alkaloid from the roots of Strychnos usambarensis. Poster session presented at 2000 Years of Natural Products Research - Past, Present and Future, Amsterdam, Netherlands.

Brandt, V., Geerlings, A., Tits, M., Penelle, J., Frederich, M., van der Heijden, R., Verpoorte, R., & Angenot, L. (July 1999). Kinetic properties of strictosidine glucosidase from Catharanthus roseus and on the new glucosidase from Strychnos mellodora in presence of strictosidine, dolichantoside and palicoside. Poster session presented at 2000 years of Natural Products Research - Past, Present and Future, Amsterdam, Netherlands.

Penelle, J., Tits, M., Christen, P., Frederich, M., & Angenot, L. (July 1999). Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis. Poster session presented at 2000 Years of Natural Products Research - Past, Present and Future, Amsterdam, Netherlands.

Penelle, J., Tits, M., Christen, P., Brandt, V., Frederich, M., & Angenot, L. (June 1999). Guiaflavine, a New Bisindole Quaternary Alkaloid from the Stem Bark of Strychnos Guianensis. Journal of Natural Products, 62 (6), 898-900. doi:10.1021/np9804738
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., HAYETTE, M.-P., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (May 1999). Isolement, détermination de structure et activité antimalarique de la 10'-hydroxyusambarensine: un nouvel alcaloïde bisindolique provenant des racines du Strychnos usambarensis. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Frederich, M., Tits, M., HAYETTE, M.-P., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (May 1999). Isolation, structure determination and antimalarial activity of 10'hydroxyusambarensine: a new bisindole alkaloid from the roots of Strychnos usambarensis. Paper presented at 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Penelle, J., Tits, M., Christen, P., Frederich, M., & Angenot, L. (May 1999). Guiaflavine, un nouvel alcaloïde quaternaire bisindolique isolé à partir de l'écorce de tige du Strychnos guianensis. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Penelle, J., Tits, M., Christen, P., Frederich, M., & Angenot, L. (May 1999). Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis. Paper presented at 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Brandt, V., Tits, M., Geerlings, A., Frederich, M., Penelle, J., Delaude, C., Verpoorte, R., & Angenot, L. (May 1999). Quatre alcaloïdes à noyau bèta-carboline isolés des écorces de tronc du Strychnos mellodora. Poster session presented at 13èmes Journées Franco-Belges de Pharmacochimie, Liège, Belgium.

Brandt, V., Tits, M., Geerlings, A., Frederich, M., Penelle, J., Delaude, C., Verpoorte, R., & Angenot, L. (May 1999). Beta-Carboline Glucoalkaloids from Strychnos mellodora. Paper presented at 8th Forum of Pharmaceutical Sciences, Spa, Belgium.

Frederich, M., Tits, M., Hayette, M.-P., Brandt, V., Penelle, J., De Mol, P., Llabres, G., & Angenot, L. (April 1999). 10'-Hydroxyusambarensine, a New Antimalarial Bisindole Alkaloid from the Roots of Strychnos Usambarensis. Journal of Natural Products, 62 (4), 619-21. doi:10.1021/np980375m
Peer Reviewed verified by ORBi

Frederich, M., HAYETTE, M.-P., De Pauw-Gillet, M.-C., Tits, M., Angenot, L., & De Mol, P. (1999). In vitro activity of african Strychnos alkaloids against chloroquine resistant plasmodium falciparum. Poster session presented at 39th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), ASM’s Annual meeting in infectious diseases, San Fransisco, United States.

Quetin-Leclercq, J., Schomer, G., Van Bambeke, F., De Pauw-Gillet, M.-C., Frederich, M., Angenot, L., & Mingeot-Leclercq, M.-P. (1999). Lysosomal phospholipases inhibition by emetine, strychnopentamine and usambarensine. Poster session presented at 2000 Years of Natural Product Research, -Past, Present and Future, Joint Meeting of the ASP, AFERP, GA and PSE, Amsterdam, Netherlands.

Dassonneville, L., Wattez, N., Mahieu, C., Colson, P., Houssier, C., Frederich, M., Tits, M., Angenot, L., & Bailly, C. (1999). The plant alkaloid usambarensine intercalates into DNA and induces apoptosis in human HL60 leukemia cells. Anticancer Research, 19 (6B), 5245-5250.
Peer Reviewed verified by ORBi

Brandt, V., Tits, M., Geerlings, A., Frederich, M., Penelle, J., Delaude, C., Verpoorte, R., & Angenot, L. (1999). beta-carboline glucoalkaloids from Strychnos mellodora. Phytochemistry, 51 (8), 1171-1176. doi:10.1016/S0031-9422(99)00129-6
Peer Reviewed verified by ORBi

Biala, R. G., Tits, M., Penelle, J., Frederich, M., Brandt, V., Prosperi, C., Llabres, G., & Angenot, L. (23 January 1998). Strychnochrysine, a New Bisindole Alkaloid from the Roots of Strychnos Nux-Vomica. Journal of Natural Products, 61 (1), 139-41. doi:10.1021/np9703454
Peer Reviewed verified by ORBi

Frederich, M., Quetin-Leclercq, J., Biala, R. G., Brandt, V., Penelle, J., Tits, M., & Angenot, L. (1998). 3 ',4 ',5 ',6 ' tetradehydrolongicaudatine Y, an anhydronium base from Strychnos usambarensis. Phytochemistry, 48 (7), 1263-1266. doi:10.1016/S0031-9422(97)00944-8
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (1998). Qualitative and quantitative evaluation of bisindole usambarane alkaloids in Strychnos usambarensis roots by high performance liquid chromatography diode-array. Phytochemical Analysis, 9 (2), 63-66. doi:10.1002/(SICI)1099-1565(199803/04)9:2<63::AID-PCA388>3.0.CO;2-9
Peer Reviewed verified by ORBi

Frederich, M., Tits, M., & Angenot, L. (April 1997). Qualitative and quantitative evaluation of bisindole usambarane alkaloids in Strychnos usambarensis roots by HPLC. Paper presented at 7th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

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