Matching an oscillator model to a phase response curve

Sacré, Pierre; Sepulchre, Rodolphe

doi:10.1109/CDC.2011.6161168

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Matching an oscillator model to a phase response curve

Sacré, Pierre; Sepulchre, Rodolphe

2011 • In Proceedings of the Joint 50th IEEE Conference on Decision and Control and European Control Conference

Peer reviewed

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https://hdl.handle.net/2268/113174

DOI
10.1109/CDC.2011.6161168

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Keywords :

Biological systems; Nonlinear systems

Abstract :

[en] The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a numerical tool based on the sensitivity analysis of the PRC to adapt initial model parameters in order to match a particular PRC shape. We illustrate the approach on a simple biochemical model of circadian oscillator.

Disciplines :

Engineering, computing & technology: Multidisciplinary, general & others

Author, co-author :

Sacré, Pierre ; Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation

Sepulchre, Rodolphe ; Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation

Language :

English

Title :

Matching an oscillator model to a phase response curve

Publication date :

December 2011

Event name :

50th IEEE Conference on Decision and Control and European Control Conference

Event organizer :

IEEE Control Systems Society (CSS)

Event place :

Orlando, United States - Florida

Event date :

12-15 Dec 2011

Audience :

International

Main work title :

Proceedings of the Joint 50th IEEE Conference on Decision and Control and European Control Conference

Pages :

3909-3914

Peer reviewed :

Peer reviewed

Available on ORBi :

since 01 March 2012

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