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Matching an oscillator model to a phase response curve
Sacré, Pierre; Sepulchre, Rodolphe
2011In Proceedings of the Joint 50th IEEE Conference on Decision and Control and European Control Conference
Peer reviewed
 

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Keywords :
Biological systems; Nonlinear systems
Abstract :
[en] The Phase Response Curve (PRC) has proven a useful tool for the reduction of complex oscillator models. It is also an information often experimentally available to the biologist. This paper introduces a numerical tool based on the sensitivity analysis of the PRC to adapt initial model parameters in order to match a particular PRC shape. We illustrate the approach on a simple biochemical model of circadian oscillator.
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Author, co-author :
Sacré, Pierre  ;  Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation
Sepulchre, Rodolphe ;  Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation
Language :
English
Title :
Matching an oscillator model to a phase response curve
Publication date :
December 2011
Event name :
50th IEEE Conference on Decision and Control and European Control Conference
Event organizer :
IEEE Control Systems Society (CSS)
Event place :
Orlando, United States - Florida
Event date :
12-15 Dec 2011
Audience :
International
Main work title :
Proceedings of the Joint 50th IEEE Conference on Decision and Control and European Control Conference
Pages :
3909-3914
Peer reviewed :
Peer reviewed
Available on ORBi :
since 01 March 2012

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