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Lassaux Patricia

GIGA Cardiovascular Sciences - MBPEL

Département des sciences biomédicales et précliniques

See author's contact details
Main Referenced Co-authors
Galleni, Moreno  (14)
Bebrone, Carine  (8)
Sohier, Jean  (7)
Frère, Jean-Marie  (6)
Laurent, Clémentine  (6)
Main Referenced Keywords
inhibition (3); metallo-beta-lactamase (3); beta-lactamase (2); coating (2); Crystallography, X-Ray (2);
Main Referenced Unit & Research Centers
CIP - Centre d'Ingénierie des Protéines - ULiège [BE] (3)
CESAM - Complex and Entangled Systems from Atoms to Materials - ULiège [BE] (1)
Center for Education and Research on Macromolecules (CERM) (1)
Center for Education and Research on Macromolecules (CERM), Belgium (1)
Complex and Entangled Systems from Atoms to Materials (CESAM) Research Unit (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (18)
Chemistry (4)
Materials science & engineering (2)
Immunology & infectious disease (2)
Microbiology (1)

Publications (total 24)

The most downloaded
501 downloads
Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Wernery, U., Lassaux, P., Steyaert, J., & Galleni, M. (15 March 2013). Allosteric inhibition of VIM metallo-beta-lactamase by a camelid nanobody. Biochemical Journal, 450 (3), 477-486. doi:10.1042/BJ20121305 https://hdl.handle.net/2268/149489

The most cited

135 citations (Scopus®)

Bebrone, C., Lassaux, P., Vercheval, L., Sohier, J., Jehaes, A., Sauvage, E., & Galleni, M. (16 April 2010). Current challenges in antimicrobial chemotherapy: focus on beta-lactamase inhibition. Drugs, 70(6), 651-679. doi:10.2165/11318430-000000000-00000 https://hdl.handle.net/2268/3887

Czuba, U., Moreno-Caranjou, M., Collard, D., De Pauw-Gillet, M.-C., Quintana, R., Lassaux, P., Detrembleur, C., & Choquet, P. (November 2020). Controlled co‐immobilization ofbiomolecules on quinone‐bearing plasma polymer films for multifunctional biomaterial surfaces. Plasma Processes and Polymers, 17 (11), 2000090. doi:10.1002/ppap.202000090
Peer Reviewed verified by ORBi

Czuba, U., Quintana, R., Lassaux, P., Bombera, R., Ceccone, G., Bañuls-Ciscar, J., Moreno-Couranjou, M., Detrembleur, C., & Choquet, P. (01 June 2019). Anti-biofouling activity of Ranaspumin-2 bio-surfactant immobilized on catechol-functional PMMA thin layers prepared by atmospheric plasma deposition. Colloids and Surfaces B: Biointerfaces, 178, 120-128. doi:10.1016/j.colsurfb.2019.02.049
Peer Reviewed verified by ORBi

Champion Olivia, O., Gourlay, L., Scott, A., Lassaux, P., Conejero, L., Perletti, L., Hemsley, C., Prior, J., Bancroft, G., Bolognesi, M., & Titball, R. W. (2016). Immunisation with proteins expressed during chronic murine melioidosis provides enhanced protection against disease. Vaccine. doi:10.1016/j.vaccine.2016.02.038
Peer Reviewed verified by ORBi

Nithichanon, A., Rinchai, D., Gori, A., Lassaux, P., Peri, C., Conchillio-Solé, O., Ferrer-Navarro, M., Gourlay, L., Nardini, M., Vila, J., Daura, X., Colombo, G., Bolognesi, M., & Lertmemonkolchai, G. (2015). Sequence- and Structure-Based Immunoreactive Epitope Discovery for Burkholderia pseudomallei Flagellin. PLoS Neglected Tropical Diseases. doi:10.1371/journal.pntd.0003917
Peer Reviewed verified by ORBi

Lassaux, P., Conchillo-Sole, O., Manjasetty, B. A., Yero, D., Perletti, L., Belrhali, H., Daura, X., Gourlay, L. J., & Bolognesi, M. (2014). Redefining the PF06864 Pfam family based on Burkholderia pseudomallei PilO2(Bp) S-SAD crystal structure. PLoS ONE, 9 (4), 94981. doi:10.1371/journal.pone.0094981
Peer Reviewed verified by ORBi

Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Wernery, U., Lassaux, P., Steyaert, J., & Galleni, M. (15 March 2013). Allosteric inhibition of VIM metallo-beta-lactamase by a camelid nanobody. Biochemical Journal, 450 (3), 477-486. doi:10.1042/BJ20121305
Peer Reviewed verified by ORBi

Gourlay, L. J., Peri, C., Ferrer-Navarro, M., Conchillo-Sole, O., Gori, A., Rinchai, D., Thomas, R. J., Champion, O. L., Michell, S. L., Kewcharoenwong, C., Nithichanon, A., Lassaux, P., Perletti, L., Longhi, R., Lertmemongkolchai, G., Titball, R. W., Daura, X., Colombo, G., & Bolognesi, M. (2013). Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chemistry and Biology, 20 (9), 1147-56. doi:10.1016/j.chembiol.2013.07.010
Peer Reviewed verified by ORBi

Lassaux, P., Peri, C., Ferrer-Navarro, M., Gourlay, L. J., Gori, A., Conchillo-Sole, O., Rinchai, D., Lertmemongkolchai, G., Longhi, R., Daura, X., Colombo, G., & Bolognesi, M. (2013). A structure-based strategy for epitope discovery in Burkholderia pseudomallei OppA antigen. Structure, 21 (1), 167-75. doi:10.1016/j.str.2012.10.005
Peer Reviewed verified by ORBi

Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2012). Allosteric inhibition of VIMs metallo-β-lactamases by a camelid single-domain antibody fragment [Poster presentation]. Biomedica 2012.

Laurent, C., Sohier, J., Pardon, E., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., Wyns, L., & Galleni, M. (10 December 2011). Characterization of the inhibition of metallo-β-lactamases of subclass B1 by VHHs cAbVIM4 and cAbBCII10 [Poster presentation]. journée doctorale SFMBBM, Liège, Belgium.

Horsfall, L., Izougarhane, Y., Lassaux, P., Selevsek, N., Liénard, B., Poirel, L., Kupper, M., Hoffmann, K., Frère, J.-M., Galleni, M., & Bebrone, C. (April 2011). Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme. FEBS Journal, 278(8), 1252-1263. doi:10.1111/j.1742-4658.2011.08046.x
Peer Reviewed verified by ORBi

Lassaux, P., Traoré, D., Loisel, E., Favier, A., Docquier, J.-D., Sohier, J., Laurent, C., Bebrone, C., Frère, J.-M., Ferrer, J.-L., & Galleni, M. (2011). Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01486-09
Peer Reviewed verified by ORBi

Lassaux, P. (2010). Caractérisation biochimique et structurale de la métallo-β-lactamase VIM-4. Sélection de nouveaux inhibiteurs de métallo-β-lactamase [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/314950

Bebrone, C., Lassaux, P., Vercheval, L., Sohier, J., Jehaes, A., Sauvage, E., & Galleni, M. (16 April 2010). Current challenges in antimicrobial chemotherapy: focus on beta-lactamase inhibition. Drugs, 70(6), 651-679. doi:10.2165/11318430-000000000-00000
Peer Reviewed verified by ORBi

Lassaux, P., Hamel, M., Gulea, M., Delbrück, H., Mercuri, P., Horsfall, L., Dehareng, D., Kupper, M., Frère, J.-M., Hoffmann, K., Galleni, M., & Bebrone, C. (2010). Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-β-lactamases. Journal of Medicinal Chemistry, 53, 4862–4876. doi:10.1021/jm100213c
Peer Reviewed verified by ORBi

Sohier, J., Laurent, C., Pardon, E., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., Wyns, L., & Galleni, M. (2010). cAbVIM4, a nanobody inhibiting the metallo-β-lactamase VIM-4 [Poster presentation]. 35th FEBS Congress: Molecules of Life, Göteborg, Sweden.

Sohier, J., Laurent, C., Pardon, E., Srinivasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2010). CA1838, A NANOBODY INHIBITING THE METALLO-β-LACTAMASE VIM-4 [Poster presentation]. Single Domain Antibodies Come of Age.

Lassaux, P., Delbrück, H., Gulea, M., Kupper, M., Hoffmann, K., Galleni, M., & Bebrone, C. (2010). Interactions mediating the positioning of mercapto-phosphonate inhibitors in the active site of metallo-beta-lactamases [Paper presentation]. ECCMID, Vienne, Austria.
Peer reviewed

Minond, D., Saldanha, S. A., Spaargaren, M., Spicer, T., Fotsing, J. R., Weide, T., Fokin, V. V., Sharpless, K. B., Galleni, M., Bebrone, C., Lassaux, P., & Hodder, P. (15 July 2009). Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries. Bioorganic and Medicinal Chemistry, 17, 5027-37. doi:10.1016/j.bmc.2009.05.070
Peer Reviewed verified by ORBi

Beck, J., Vercheval, L., Bebrone, C., Herteg-Fernea, A., Lassaux, P., & Marchand-Brynaert, J. (01 July 2009). Discovery of novel lipophilic inhibitors of OXA-10 enzyme (class D beta-lactamase) by screening amino analogs and homologs of citrate and isocitrate. Bioorganic and Medicinal Chemistry Letters, 19, 3593-7. doi:10.1016/j.bmcl.2009.04.149
Peer Reviewed verified by ORBi

Beck, J., Gharbi, S., Herteg-Fernea, A., Vercheval, L., Bebrone, C., Lassaux, P., Zervosen, A., & Marchand-Brynaert, J. (2009). Aminophosphonic Acids and Aminobis(phosphonic acids) as Potential Inhibitors of Penicillin-Binding Proteins. European Journal of Organic Chemistry, (1), 85-97. doi:10.1002/ejoc.200800812
Peer Reviewed verified by ORBi

Lienard, B. M. R., Huting, R., Lassaux, P., Galleni, M., Frère, J.-M., & Schofield, C. J. (2008). Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors. Journal of Medicinal Chemistry, 51 (3), 684-8. doi:10.1021/jm070866g
Peer Reviewed verified by ORBi

Lienard, B. M. R., Garau, G., Horsfall, L., Karsisiotis, A. I., Damblon, C., Lassaux, P., Papamicael, C., Roberts, G. C. K., Galleni, M., Dideberg, O., Frère, J.-M., & Schofield, C. J. (2008). Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. Organic and Biomolecular Chemistry, 6 (13), 2282-2294. doi:10.1039/b802311e
Peer Reviewed verified by ORBi

Lassaux, P., Hamel, M., Gulea, M., Mercuri, P., Horsfall, L., Bebrone, C., Gaumont, A.-C., Frère, J.-M., & Galleni, M. (2007). Mercapto-phosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases. International Journal of Antimicrobial Agents, 29 (Supplément 2), 95.
Peer Reviewed verified by ORBi

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