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Galleni Moreno

Département des sciences de la vie > Macromolécules biologiques

InBioS

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Main Referenced Co-authors
Frère, Jean-Marie  (122)
Mercuri, Paola  (45)
Matagne, André  (32)
Amicosante, G. (30)
Bebrone, Carine  (29)
Main Referenced Keywords
Kinetics (26); Molecular Sequence Data (19); Amino Acid Sequence (17); Binding Sites (14); Base Sequence (9);
Main Referenced Unit & Research Centers
CIP - Centre d'Ingénierie des Protéines - ULiège [BE] (21)
Center for Education and Research on Macromolecules (CERM) (10)
Centre d'Ingénierie des protéines - Université de Liège (5)
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE] (4)
Center for Cancer and Immunology Research- Université d'Angers (2)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (231)
Microbiology (35)
Chemistry (20)
Pharmacy, pharmacology & toxicology (14)
Veterinary medicine & animal health (13)

Publications (total 292)

The most downloaded
1272 downloads
Gangoue Pieboji, J., Eze, N., Ngongang Djintchui, A., Ngameni, B., Tsabang, N., Pegnyemb, D. E., Biyiti, L., Ngassam, P., Koulla-Shiro, S., & Galleni, M. (2009). The in-vitro antimicrobial activity of some medicinal plants against beta-lactam-resistant bacteria. Journal of Infection in Developing Countries, 3 (9), 671-80. doi:10.3855/jidc.77 https://hdl.handle.net/2268/62988

The most cited

415 citations (Scopus®)

Carfi, A., Pares, S., Duée, E., Galleni, M., Duez, C., Frère, J.-M., & Dideberg, O. (1995). The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO Journal, 14 (20), 4914-4921. doi:10.1002/j.1460-2075.1995.tb00174.x https://hdl.handle.net/2268/3925

Cawez, F., Mercuri, P., Piccirilli, A., Perilli, M., Morales Yánez, F. J., Dumoulin, M., & Galleni, M. (02 June 2023). Selection and characterization of anti-NDM-1 nanobodies [Poster presentation]. 14 th Beta-Lactam and beta-lactamase meeting, L'Aquila, Italy.

Zouaoui, E., Mercuri, P., Radaoui, A., Ben Salah, N., Galleni, M., Ben-Mahrez, K., & Réjiba, S. (2023). High Prevalence of blaNDM Among Carbapenem Non‑Susceptible Klebsiella pneumoniae in a Tunisian Hospital First Report of blaNDM‑9, blaKPC‑20, and blaKPC‑26 Genes. Current Microbiology, 80 (152). doi:10.1007/s00284-023-03268-2
Peer Reviewed verified by ORBi

Cawez, F., Mercuri, P., Morales Yánez, F. J., Maalouf, R., Vandevenne, M., Kerff, F., Guérin, V., Mainil, J., Thiry, D., Saulmont, M., Vanderplasschen, A., Lafaye, P., Aymé, G., Bogaerts, P., Dumoulin, M., & Galleni, M. (2023). Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C b-Lactamases. Antimicrobial Agents and Chemotherapy. doi:10.1128/aac.01499-22
Peer Reviewed verified by ORBi

Gavara, L., Verdirosa, F., Sevaille, L., Legru, A., Corsica, G., Nauton, L., Mercuri, P., Sannio, F., De Luca, F., Hadjadj, M., Cerboni, G., Vo Hoang, Y., Licznar-Fajardo, P., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (11 August 2022). 1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors. Bioorganic and Medicinal Chemistry, 72, 116964. doi:10.1016/j.bmc.2022.116964
Peer Reviewed verified by ORBi

Verdirosa, F.* , Gavara, L.* , Sevaille, L., Tassone, G., Corsica, G., Legru, A., Feller, G., Chelini, G., Mercuri, P., Tanfoni, S., Sannio, F., Benvenuti, M., Cerboni, G., De Luca, F., Bouajila, E., Hoang, Y. V., Licznar-Fajardo, P., Galleni, M., Pozzi, C., ... Hernandez, J.-F.*. (20 January 2022). 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors. ChemMedChem, 17 (7), 202100699. doi:10.1002/cmdc.202100699
Peer reviewed
* These authors have contributed equally to this work.

Lupo, V., Mercuri, P., Frère, J.-M., Joris, B., Galleni, M., Baurain, D.* , & Kerff, F.*. (2022). An Extended Reservoir of Class-D Beta-Lactamases in Non-Clinical Bacterial Strains. Microbiology Spectrum, 10 (2), 0031522. doi:10.1128/spectrum.00315-22
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Guérin, V., Farchi, A., Thiry, D., Cawez, F., Mercuri, P., Galleni, M., Mainil, J., & Saulmont, M. (2022). Seven-Year Evolution of β-Lactam Resistance Phenotypes in Escherichia coli Isolated from Young Diarrheic and Septicaemic Calves in Belgium. Veterinary Sciences. doi:10.3390/vetsci9020045
Peer Reviewed verified by ORBi

de Barsy, M., Mercuri, P., Oueslati, S., Elisée, E., Huang, T.-D., Sacré, P., Iorga, B. I., Naas, T., Galleni, M., & Bogaerts, P. (18 October 2021). Detection and Characterization of VIM-52, a New Variant of VIM-1 from a Klebsiella pneumoniae Clinical Isolate. Antimicrobial Agents and Chemotherapy, 65 (Issue 11), 02660-20. doi:10.1128/AAC.02660-20
Peer Reviewed verified by ORBi

Toncheva-Moncheva, N., Aqil, A., Galleni, M., & Jérôme, C. (June 2021). Conversion of electrospun chitosan into chitin: a robust strategy to tune the properties of 2D biomimetic nanofiber scaffolds. Polysaccharides, 2 (2), 271-286. doi:10.3390/polysaccharides2020019
Peer reviewed

Piccirilli, A., Mercuri, P., Segatore, B., Galleni, M., Brisdelli, F., Kerff, F., Amicosante, G., & Perilli, M. (June 2021). Laboratory Variants GESG170L, GESG170K, and GESG170H Increase Carbapenem Hydrolysis and Confer Resistance to Clavulanic Acid. Antimicrobial Agents and Chemotherapy, 65 (6), 01931-20. doi:10.1128/AAC.01931-20
Peer Reviewed verified by ORBi

Collet, L., Vander Wauven, C., Dutoit, R., Oudjama, Y., & Galleni, M. (2021). Glycoside hydrolase family 5: structural snapshots highlighting the involvement of two conserved residues in catalysis. Acta Crystallographica. Section D, Structural Biology. doi:10.1107/S2059798320015557
Peer Reviewed verified by ORBi

Guérin, V., Thiry, D., Lucas, P., Blanchard, Y., Cawez, F., Mercuri, P., Galleni, M., Saulmont, M., & Mainil, J. (2021). Identification of b-Lactamase-Encoding (bla) Genes in Phenotypically b-Lactam-Resistant Escherichia coli Isolated from Young Calves in Belgium. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease. doi:10.1089/mdr.2020.0472
Peer Reviewed verified by ORBi

Gavara, L., Legru, A., Verdirosa, F., Sevaille, L., Nauton, L., Corsica, G., Mercuri, P., Sannio, F., Feller, G., Coulon, R., De Luca, F., Cerboni, G., Tanfoni, S., Chelini, G., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (2021). 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors. Bioorganic Chemistry, 113. doi:10.1016/j.bioorg.2021.105024
Peer Reviewed verified by ORBi

Piccirilli, A., Criscuolo, E., Brisdelli, F., Mercuri, P., Cherubini, S., De Scicio, M. L., Maccarrone, M., Galleni, M., Amicosante, G., & Perilli, M. (2021). Exploring the Role of L10 Loop in New Delhi Metallo- beta-lactamase (NDM-1): Kinetic and Dynamic Studies. Molecules, 26, 5489. doi:10.3390/molecules26185489
Peer reviewed

Mercuri, P., Esposito, R., Blétard, S., Di Costanzo, S., Perilli, M., Kerff, F., & Galleni, M. (2020). Mutational Effects on Carbapenem Hydrolysis of YEM-1, a New Subclass B2 Metallo-β-Lactamase from Yersinia mollaretii. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.00105-20
Peer Reviewed verified by ORBi

Gavara, L., Sevaille, L., De Luca, F., Mercuri, P., Bebrone, C., Feller, G., Legru, A., Cerboni, G., Tanfoni, S., Baud, D., Cutolo, G., Bestgen, B., Chelini, G., Verdirosa, F., Sannio, F., Pozzi, C., Benvenuti, M., Kwapien, K., Fischer, M., ... Hernandez, J.-F. (2020). 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-beta-lactamase inhibitors. European Journal of Medicinal Chemistry, 208, 112720. doi:10.1016/j.ejmech.2020.112720
Peer Reviewed verified by ORBi

Gavara, L., Verdirosa, F., Legru, A., Mercuri, P., Nauton, L., Sevaille, L., Feller, G., Berthomieu, D., Sannio, F., Marcoccia, F., Tanfoni, S., De Luca, F., Gresh, N., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (2020). 4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-Beta-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition. Biomolecules, 10 (8), 1094. doi:10.3390/biom10081094
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Mack, A. R., Barnes, M. D., Taracila, M. A., Hujer, A. M., Hujer, K. M., Cabot, G., Feldgarden, M., Haft, D. H., Klimke, W., Van Den Akker, F., Vila, A. J., Smania, A., Haider, S., Papp-Wallace, K. M., Bradford, P. A., Rossolini, G. M., Docquier, J.-D., Frère, J.-M., Galleni, M., ... Bonomo, R. A. (2020). A standard numbering scheme for class C β-lactamases. Antimicrobial Agents and Chemotherapy, 64 (3). doi:10.1128/AAC.01841-19
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Ceasar, S. A., Lekeux, G., Motte, P., Xiao, Z., Galleni, M., & Hanikenne, M. (2020). di-Cysteine Residues of the Arabidopsis thaliana HMA4 C-Terminus Are Only Partially Required for Cadmium Transport. Frontiers in Plant Science, 11, 560. doi:10.3389/fpls.2020.00560
Peer Reviewed verified by ORBi

Mercuri, P., Esposito, R., Blétard, S., Di Costanzo, S., Perilli, M., Kerff, F., & Galleni, M. (22 June 2019). Mutational Effects in Carbapenem Hydrolysis of YEM-1, a New Sub-Class B2 Metallo-beta-Lactamase from Yersinia mollaretii [Poster presentation]. asm microbe, San Francisco Ca, United States.

De Franco, S., Vandenameele, J., Brans, A., Verlaine, O., Bendak, K., Damblon, C., Matagne, A., Segal, D., Galleni, M., Mackay, J., & Vandevenne, M. (21 February 2019). Exploring the suitability of RanBP2-type Zinc Fingers for RNA-binding protein design. Scientific Reports, 9 (1), 2484. doi:10.1038/s41598-019-38655-y
Peer Reviewed verified by ORBi

Lekeux, G.* , Crowet, J.-M.* , Nouet, C., Joris, M., Jadoul, A., Bosman, B., Carnol, M., Motte, P., Lins, L., Galleni, M., & Hanikenne, M. (2019). Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase. Journal of Experimental Botany, 70, 329-341. doi:10.1093/jxb/ery353
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Belet, A., Dondelinger, M., Gommes, C., Galleni, M., & Heinrichs, B. (2019). Enzyme Immobilization on Ordered Mesoporous Materials [Paper presentation]. XX International Sol-Gel Conference, Saint- Petersbourg, Russia.

Guérin, V., Thiry, D., Galleni, M., Saulmont, M., & Mainil, J. (26 October 2018). β-lactamase-encoding gene identification by microarrays in phenotypically resistant Escherichia coli from young calves in Wallonia, Belgium [Paper presentation]. 5th FARAH DAY.

Dondelinger, M., Filée, P., Sauvage, E., Quinting, B., Muyldermans, S., Galleni, M., & Vandevenne, M. (16 October 2018). Understanding the significance and implications of antibody numbering and antigen-binding surface/residue definition. Frontiers in Immunology, 9 (OCT). doi:10.3389/fimmu.2018.02278
Peer Reviewed verified by ORBi

Guérin, V., Thiry, D., Galleni, M., Saulmont, M., & Mainil, J. (August 2018). Beta-lactamase-encoding gene identification by micro-arrays in phenotypically resistant pathogenic Escherichia coli from young calves in Wallonia, Belgium [Paper presentation]. The 30th World Buiatric Congress 2018 Sapporo, Sapporo, Japan.

Cawez, F., Duray, E., Hu, Y., Vandenameele, J., Romao, E., Vinckle, C., Dumoulin, M., Galleni, M., Muyldermans, S., & Vandevenne, M. (25 May 2018). Combinatorial Design of a Nanobody that Specifically Targets Structured RNAs. Journal of Molecular Biology, 430 (11), 1652-1670. doi:10.1016/j.jmb.2018.03.032
Peer Reviewed verified by ORBi

Vandevenne, M., Dondelinger, M., Yunus, S., Freichels, A., Freichels, R., Crasson, O., Rhazi, N., Bogaerts, P., Galleni, M., & Filée, P. (2018). The use of a β-lactamase – based conductimetric biosensor assay to detect biomolecular interactions. Journal of Visualized Experiments, (132). doi:10.3791/55414
Peer Reviewed verified by ORBi

Marcoccia, F., Mercuri, P., Galleni, M., Celenza, G., Amicosante, G., & Perilli, M. (2018). A Kinetic Study of the Replacement by Site Saturation Mutagenesis of Residue 119 in NDM-1 Metallo- beta-Lactamase. Antimicrobial Agents and Chemotherapy, 62 (8). doi:10.1128/AAC.02541-17
Peer Reviewed verified by ORBi

Lekeux, G., Laurent, C., Joris, M., Jadoul, A., Jiang, D., Bosman, B., Carnol, M., Motte, P., Xiao, Z., Galleni, M., & Hanikenne, M. (2018). di-Cysteine motifs in the C-terminus of plant HMA4 proteins confer nanomolar affinity for zinc and are essential for HMA4 function in vivo. Journal of Experimental Botany, 69 (22), 5547-5560. doi:10.1093/jxb/ery311
Peer Reviewed verified by ORBi

Pérez-Llarena, F. J., Vázquez-Ucha, J. C., Kerff, F., Zamorano, L., Beceiro, A., Miro, E., Póvoa Cabral, M., Fleites, A., Lantero, M., Martínez-Martínez, L., Martínez-Martínez, A., Galleni, M., Navarro, F., & Bou, G. (2018). Increased antimicrobial resistance in a novel CMY-54 AmpC-type enzyme with a GluLeu217-218 insertion in the Ω-loop. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease. doi:10.1089/mdr.2017.0017
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Piccirilli, A., Mercuri, P., Galleni, M., Aschi, M., Matagne, A., Amicosante, G., & Perilli, M. (2018). P174E Substitution in GES-1 and GES-5 beta-Lactamases Improves Catalytic Efficiency toward Carbapenems. Antimicrobial Agents and Chemotherapy, 62 (5). doi:10.1128/AAC.01851-17
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Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., & Frank, B. (06 September 2017). Protein-polysaccharide complexes, a tool for protein delivery in CaCO3 microparticles [Poster presentation]. Annual Conference of the European Society of Biomaterials, Athens, Greece.

Ramalapa, B., Crasson, O., Vandevenne, M., Emmanuel, G., Alain, G., Galleni, M., Boury, F., & Cordonnier, T. (16 August 2017). Protein–polysaccharide complexes for enhanced protein delivery in hyaluronic acid templated calcium carbonate microparticles. Journal of Materials Chemistry B, 5, 7360-7368. doi:10.1039/C7TB01538K
Peer Reviewed verified by ORBi

Lekeux, G., Laurent, C., Xiao, Z., Crowet, J.-M., Lins, L., Hanikenne, M., & Galleni, M. (24 July 2017). Functional and structural characterisation of the Arabidopsis thaliana HMA4 protein [Poster presentation]. Cell Biology of Metals - Godon Research Conference, West Dover, United States.

Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., & Frank, B. (17 July 2017). Protein-polysaccharide complexes for improved protein delivery within CaCO3 microparticles [Paper presentation]. Controlled Release Society Meeting, Boston, United States.

Rodríguez, M. M., Herman, R., Ghiglione, B., Kerff, F., D'Amico González, G., Bouillenne, F., Galleni, M., Handelsman, J., Charlier, P., Gutkind, G., Sauvage, E., & Power, P. (July 2017). Crystal Structure and Kinetic Analysis of the Class B3 Di-Zinc Metallo-β-Lactamase LRA-12 from an Alaskan Soil Metagenome. PLoS ONE, 12 (7), 0182043. doi:10.1371/journal.pone.0182043
Peer Reviewed verified by ORBi

Amisano, F., Silvestri, M., Mercuri, P., Gagliardi, A., Bini, L., Frère, J.-M., & Galleni, M. (17 June 2017). Study of the outer membrane permeability of Pseudomonas aeruginosa to ß-lactam antibiotics [Poster presentation]. 13th Beta lactamase meeting, Santo Stefano di Sessanio, Italy.

Mercuri, P., Blétard, S., Kerff, F., & Galleni, M. (June 2017). Characterisation of the sub-class B2 metallo-β-lactamase of Yersinia mollaretii Wauters [Poster presentation]. 13th β-lactamase Meeting", Santo Stefano di Sessanio, l'Aquila, Italy.

Piccirilli, A., Perilli, M., Mercuri, P., Aschi, M., Segatore, B., Galleni, M., Celenza, G., & Amicosante, G. (June 2017). Replacement of proline 174 with glutamic acid in GES-1 enzyme improve the flexibility of Ω-loop leading to an increase of catalytic efficiency towards carbapenems [Poster presentation]. 13th β-lactamase Meeting", Santo Stefano di Sessanio, l'Aquila, Italy.

Marcoccia, F., Melchiorre, C., Robert, C., Mercuri, P., Galleni, M., Celenza, G., Amicosante, G., & Perilli, M. (June 2017). NDM-1 could still evolve: analysis of a random mutagenesis in position 123 [Poster presentation]. 13th β-lactamase Meeting", Santo Stefano di Sessanio, l'Aquila, Italy.

Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., & Frank, B. (30 May 2017). Improved encapsulation of proteins within calcium carbonate microparticles by means of protein-polysaccharide complexes [Poster presentation]. Journée Scientifique SFR Santé, Angers, France.

Crasson, O., Courtade, G., Léonard, R., Aachmann, F., Legrand, F., Parente, R., Baurain, D., Galleni, M., Sorlie, M., & Vandevenne, M. (2017). Human chitotriosidase: Catalytic domain or carbohydrate binding module, who's leading HCHT's biological function. Scientific Reports, 7 (1). doi:10.1038/s41598-017-02382-z
Peer Reviewed verified by ORBi

Chevigne, A., Campizi, V., Szpakowska, M., Bourry, D., Dumez, M.-E., Martins, J. C., Matagne, A., Galleni, M., & Jacquet, A. (2017). The Lys-Asp-Tyr Triad within the Mite Allergen Der p 1 Propeptide Is a Critical Structural Element for the pH-Dependent Initiation of the Protease Maturation. International Journal of Molecular Sciences, 18 (5). doi:10.3390/ijms18051087
Peer Reviewed verified by ORBi

Sevaille, L., Gavara, L., Bebrone, C., De Luca, F., Nauton, L., Achard, M., Mercuri, P., Tanfoni, S., Borgianni, L., Guyon, C., Lonjon, P., Turan-Zitouni, G., Dzieciolowski, J., Becker, K., Bénard, L., Condon, C., Maillard, L., Martinez, J., Frère, J.-M., ... Hernandez, J.-F. (2017). 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases. ChemMedChem, 12, 972-985. doi:10.1002/cmdc.201700186
Peer Reviewed verified by ORBi

De Franco, S., Vandenameele, J., Galleni, M., & Vandevenne, M. (29 June 2016). Exploring potentialities of RanbP2-type Zinc Fingers in RNA-binding proteins design [Poster presentation]. RNA 2016- The RNA Society of Japan 18th Annual Meeting and the 21st Annual Meeting of the RNA Society, Kyoto, Japan.

Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., Boury, F., & Cordonnier, T. (22 March 2016). The use of protein-polysaccharide complexes to enhance protein delivery in CaCO3 microparticles [Paper presentation]. FADEX 2016 Nanoparticles for Medicine, Grenoble, France.

Fernea, A., Galleni, M., & Frère, J.-M. (2016). Kinetics of the Interaction between BAL29880 and LK157 and the Class C β-Lactamase CHE-1. Antimicrobial Agents and Chemotherapy, 60, 1747-1750. doi:10.1128/AAC.02062-15
Peer Reviewed verified by ORBi

Marcoccia, F., Bottoni, C., Sabatini, A., Colapietro, M., Mercuri, P., Galleni, M., Kerff, F., Matagne, A., Celenza, G., Amicosante, G., & Perilli, M. (2016). Kinetic Study of Laboratory Mutants of NDM-1 Metallo-beta-Lactamase and the Importance of an Isoleucine at Position 35. Antimicrobial Agents and Chemotherapy, 60 (4), 2366-72. doi:10.1128/AAC.00531-15
Peer Reviewed verified by ORBi

Bottoni, C., Perilli, M., Marcoccia, F., Piccirilli, A., Pellegrini, C., Colapietro, M., Sabatini, A., Celenza, G., Kerff, F., Amicosante, G., Galleni, M., & Mercuri, P. (2016). Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems. Antimicrobial Agents and Chemotherapy, 60 (5), 3123-6. doi:10.1128/AAC.01703-15
Peer Reviewed verified by ORBi

Laurent, C.* , Lekeux, G.* , Ukuwela, A. A., Xiao, Z., Charlier, J.-B., Bosman, B., Carnol, M., Motte, P., Damblon, C., Galleni, M., & Hanikenne, M. (2016). Metal binding to the N-terminal cytoplasmic domain of the PIB ATPase HMA4 is required for metal transport in Arabidopsis. Plant Molecular Biology, 90, 453-466. doi:10.1007/s11103-016-0429-z
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Ramalapa, B., Crasson, O., Vandevenne, M., Galleni, M., Cordonnier, T., & Boury, F. (10 December 2015). Design of new delivery systems for therapeutic proteins based on calcium carbonate microspheres [Poster presentation]. Ecole doctorale biologie santé journées scientifique, Nantes, France.

Lekeux, G., Laurent, C., Hanikenne, M., & Galleni, M. (03 December 2015). Functional and structural characterization of the Arabidopsis thaliana HMA4 protein [Poster presentation]. IAP 7/44 Meeting - Integrative Protein Science: from small molecules to complex biological systems – iPros, Leuven, Belgium.

Crowet, J.-M., Lekeux, G., Hanikenne, M., Brasseur, R., Galleni, M., & Lins, L. (03 December 2015). Molecular modelling of the metal ATPase HMA4 from Arabidopsis halleri [Poster presentation]. IAP 7/44 Meeting: Integrative Protein Science: from small molecules to complex biological systems - iPros.

Crasson, O., Rhazi, N., Jacquin, O., Freichels, A., Jérôme, C., Ruth, N., Galleni, M., Filée, P., & Vandevenne, M. (October 2015). Enzymatic functionalization of a nanobody using protein insertion technology. Protein Engineering, Design and Selection, 28 (10), 451-460. doi:10.1093/protein/gzv020
Peer Reviewed verified by ORBi

Crasson, O., Legrand, F., Léonard, R., Baurain, D., Galleni, M., & Vandevenne, M. (August 2015). The hidden face of the human macrophage chitotriosidase: taking a new look at this enzyme based on the biochemical and phylogenomic analysis of its chitin binding domain [Poster presentation]. Gordon Research Conferences : Cellulosomes, Cellulases & Other Carbohydrate Modifying Enzymes, Andover MA, United States.

Freichels, R., Delmarcelle, M., Colarusso, A., Kerff, F., Wathelet, B., & Galleni, M. (July 2015). SPECIFICITY OF CLASS I TAGATOSE 1,6-BISPHOSPHATE ALDOLASE ENHANCED TOWARD TAGATOSE 1,6-BISPHOPHATE [Poster presentation]. 12th Biotrans, Vienne, Austria.

Lekeux, G., Laurent, C., Galleni, M., & Hanikenne, M. (08 June 2015). Functional and structural analysis of the Arabidopsis thaliana HMA4 protein [Poster presentation]. AIP meeting 2015.

Laurent, C., Lekeux, G., Damblon, C., Hanikenne, M., & Galleni, M. (08 June 2015). Functional and structural characterization of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. IAP meeting.

Galleni, M., Kerff, F., & Rigali, S. (05 February 2015). Résistance aux antibiotiques : le retour à l’ère prébiotique ? [Paper presentation]. Liège Creative.

Fernea, A., Galleni, M., & Frère, J.-M. (2015). Kinetics of the interaction between avibactam and the CHE-1 class C beta-lactamase. Journal of Antimicrobial Chemotherapy, 70 (3), 951-953. doi:10.1093/jac/dku442
Peer Reviewed verified by ORBi

Ghiglione, B., Rodriguez, M. M., Herman, R., Curto, L., Dropa, M., Bouillenne, F., Kerff, F., Galleni, M., Charlier, P., Gutkind, G., Sauvage, E., & Power, P. (2015). Structural and Kinetic Insights into the "Ceftazidimase" Behavior of the Extended-Spectrum beta-Lactamase CTX-M-96. Biochemistry, 54 (32), 5072-82. doi:10.1021/acs.biochem.5b00313
Peer Reviewed verified by ORBi

Pujol, J., Bouillenne, F., Farnir, F., Dufrasne, I., Mainil, J., Galleni, M., Lekeux, P., Bureau, F.* , & Fievez, L.*. (2015). Generation of a soluble recombinant trimeric form of bovine CD40L and its potential use as a vaccine adjuvant in cows. Veterinary Immunology and Immunopathology, 168 (1), 1-13. doi:10.1016/j.vetimm.2015.09.011
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Bouaziz, A., Walgraffe, D., Bouillot, C., Herman, J., FOGUENNE, J., Gothot, A., Louis, R., Hentges, F., Jacquet, A., Mailleux, A.-C., Chevigne, A., Galleni, M., Adam, E., & Dumez, M.-E. (2015). Development of recombinant stable house dust mite allergen Der p 3 molecules for component-resolved diagnosis and specific immunotherapy. Clinical and Experimental Allergy, 45. doi:10.1111/cea.12452
Peer Reviewed verified by ORBi

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (14 November 2014). Structural and functional characterization of the Arabidopsis halleri HMA4 protein [Poster presentation]. Journée doctorale Namur "Industrial researches in structural biological chemistry".

Lekeux, G., Laurent, C., Damblon, C., Galleni, M., & Hanikenne, M. (09 September 2014). Structural and functional analysis of the HMA4 protein [Poster presentation]. Summer school-Chemistry of metals in biological systems.

Freichels, R., Colarusso, A., Delmarcelle, M., Kerff, F., Wathelet, B., & Galleni, M. (01 June 2014). Structural studies of class I tagatose 1,6-bisphosphate aldolase : Enhanced substrate specificity toward tagatose 1,6-bisphosphate [Poster presentation]. EMBO : Enzyme mechanisms by biological systems, Manchester (UK), United Kingdom.

Henrottin, J., Zervosen, A., Lemaire, C., Sapunaric, F., Laurent, S., Galleni, M., Van den Eynde, B., Goldman, S., Plenevaux, A., & Luxen, A. (June 2014). Synthesis of N-fluoroalkyl-tryptophan and study of their biological activity as potential substrates for indoleamine 2,3-dioxygenase [Poster presentation]. French-American Chemical society Symposium - FACS XV.

Crasson, O., Galleni, M., Parente, R. (Other coll.), Vandevenne, M. (Other coll.), & Filée, P. (Other coll.). (15 May 2014). How to build a biological linker dedicated to the engineering of novel drug delivery systems [Poster presentation]. Bioforum.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (15 May 2014). Structural and functional analysis of the Arabidopsis halleri HMA4 protein [Poster presentation]. Bioforum 2014.

Lekeux, G., Laurent, C., Damblon, C., Galleni, M., & Hanikenne, M. (06 May 2014). Structural and functional study of the Arabidopsis halleri HMA4 protein [Poster presentation]. PhytoSYSTEMS day.

Perez, A., Perez-Llarena, F. J., Garcia, P., Kerff, F., Beceiro, A., Galleni, M., & Bou, G. (2014). New mutations in ADC-type beta-lactamases from Acinetobacter spp. affect cefoxitin and ceftazidime hydrolysis. Journal of Antimicrobial Chemotherapy. doi:10.1093/jac/dku163
Peer Reviewed verified by ORBi

Perez-Llarena, F. J., Zamorano, L., Kerff, F., Beceiro, A., Garcia, P., Miro, E., Larrosa, N., Gomez-Bertomeu, F., Mendez, J. A., Gonzalez-Lopez, J. J., Oliver, A., Galleni, M., Navarro, F., & Bou, G. (2014). Genetic and kinetic characterization of the novel AmpC beta-lactamases DHA-6 and DHA-7. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.03144-14
Peer Reviewed verified by ORBi

Ruggiero, M., Kerff, F., Herman, R., Sapunaric, F., Galleni, M., Gutkind, G., Charlier, P., Sauvage, E., & Power, P. (2014). Crystal Structure of the Extended-Spectrum β -Lactamase PER-2 and Insights into the Role of Specific Residues in the Interaction with β -Lactams and β -Lactamase Inhibitors. Antimicrobial Agents and Chemotherapy, 58 (10), 5994-6002. doi:10.1128/AAC.00089-14
Peer Reviewed verified by ORBi

Power, P., Sauvage, E., Herman, R., Gutkin, G., Galleni, M., Charlier, P., & Kerff, F. (2014). The crystal structure of the carbapenemase OXA-24 in complex with tazobactam reveals evidences about the intereaction with beta-lactamase inhibitors and lysine carboxylation [Poster presentation]. 54th Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, United States - District of Columbia.

Herman, J., Thelen, N., Smargiasso, N., Mailleux, A.-C., Luxen, A., Cloes, M., De Pauw, E., Chevigné, A., Galleni, M., & Dumez, M.-E. (2014). Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus. Biochimica et Biophysica Acta - General Subjects, 1840 (3), 1117–1124. doi:10.1016/j.bbagen.2013.11.017
Peer Reviewed verified by ORBi

Achour, N. B., Belhadj, O., Galleni, M., Moussa, M. B., & Mercuri, P. (2014). Study of a Natural Mutant SHV-Type beta-Lactamase, SHV-104, from Klebsiella pneumoniae. International Journal of Microbiology, 2014. doi:10.1155/2014/548656
Peer Reviewed verified by ORBi

Dumez, M.-E., Herman, J., Campizi, V., Galleni, M., Jacquet, A., & Chevigne, A. (2014). Orchestration of an uncommon maturation cascade of the house dust mite protease allergen quartet. Frontiers in Immunology, 5, 138. doi:10.3389/fimmu.2014.00138
Peer Reviewed verified by ORBi

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (15 November 2013). Structural and functional analysis of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. SFMBBM Doctoral School.

Huynen, C., Filée, P., Matagne, A., Galleni, M., & Dumoulin, M. (28 August 2013). Class A β -Lactamases as Versatile Scaffolds to Create Hybrid Enzymes: Applications from Basic Research to Medicine. BioMed Research International, 2013, 16. doi:10.1155/2013/827621
Peer Reviewed verified by ORBi

Van Der Heiden, E., Delmarcelle, M., Lebrun, S., Freichels, R., Brans, A., Vastenavond, C. M., Galleni, M., & Joris, B. (June 2013). A Pathway closely related to the D-tagatose pathway of Gram-Negative Enterobacteria Identified in the Gram-Positive Bacterium Bacillus licheniformis. Applied and Environmental Microbiology, 79 (11), 3511-3515. doi:10.1128/AEM.03918-12
Peer Reviewed verified by ORBi

Van Der Heiden, E., Delmarcelle, M., Lebrun, S., Freichels, R., Brans, A., Vastenavond, C. M., Galleni, M., & Joris, B. (June 2013). A Pathway closely related to the D-tagatose pathway of Gram-Negative Enterobacteria Identified in the Gram-Positive Bacterium Bacillus licheniformis [Poster presentation]. 7th International conference on Gram-positive Microorganisms, Montecatini, Italy.

Henrottin, J., Zervosen, A., Lemaire, C., Galleni, M., & Luxen, A. (May 2013). Automated radiosynthesis of 1-(2-[18F]fluoroethyl)-tryptophan, a potential substrate for indoleamine 2,3-dioxygenase PET imaging [Poster presentation]. The 20th International Symposium on Radiopharmaceutical Sciences - ISRS 2013, Jéju, South Korea.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (18 April 2013). Structural and functional study of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. Bioforum 2013, Liège, Belgium.

Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Wernery, U., Lassaux, P., Steyaert, J., & Galleni, M. (15 March 2013). Allosteric inhibition of VIM metallo-beta-lactamase by a camelid nanobody. Biochemical Journal, 450 (3), 477-486. doi:10.1042/BJ20121305
Peer Reviewed verified by ORBi

Freichels, R., Guarino, C., Delmarcelle, M., Kerff, F., Wathelet, B., & Galleni, M. (26 February 2013). Biochemical and Structural studies of the type I tagatose bisphosphate aldolases [Poster presentation]. IAP meeting "integrative protein science : from small molecules to complex biological systems", Liège, Belgium.

Crasson, O., Rhazi, N., Kinet, M. (Other coll.), Filée, P. (Other coll.), Stordeur, P. (Other coll.), Collard, A. (Other coll.), & Galleni, M. (Other coll.). (26 February 2013). Characterization of monoclonal antibodies against Hemolysin Alpha of Staphylococcus aureus [Poster presentation]. IAP meeting "Integrative Protein Science: from small molecules to complex biological systems", Liège, Belgium.

Lekeux, G., Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (26 February 2013). Structural and functional characterization of the Arabidopsis halleri HMA4 N-terminal domain [Poster presentation]. IAP meeting: "Integrative Protein Science: from small molecules to complex biological systems".

Berlemont, R., Spee, O., Delsaute, M., Lara, Y., Schuldes, J., Simon, C., Power, P., Daniel, R., & Galleni, M. (2013). Novel organic solvent-tolerant esterase isolated by metagenomics: insights into the lipase/esterase classification. Revista Argentina de Microbiologia, (45), 3-12.
Peer Reviewed verified by ORBi

Perilli, M., Celenza, G., Mercuri, P., Galleni, M., Pellegrini, C., Segatore, B., & Amicosante, G. (2013). R164H and V240H replacements by site-directed mutagenesis of TEM-149 extended-spectrum beta-lactamase: kinetic analysis of TEM-149H240 and TEM-149H164-H240 laboratory mutants. Antimicrobial Agents and Chemotherapy, 57 (2), 1047-9. doi:10.1128/AAC.01268-12
Peer Reviewed verified by ORBi

Delsaute, M., Berlemont, R., Dehareng, D., Van Elder, D., Galleni, M., & Bauvois, C. (2013). Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 69 (Pt 8), 828-33. doi:10.1107/S1744309113014565
Peer Reviewed verified by ORBi

Berlemont, R., Jacquin, O., Delsaute, M., La Salla, M., Georis, J., Verte, F., Galleni, M., & Power, P. (2013). Novel Cold-Adapted Esterase MHlip from an Antarctic Soil Metagenome. Biology, 2 (1), 177-88. doi:10.3390/biology2010177
Peer Reviewed verified by ORBi

Dumez, M.-E., Herman, J., Campisi, V., Bouaziz, A., Rosu, F., Luxen, A., Vandenberghe, I., De Pauw, E., Frère, J.-M., Matagne, A., Chevigne, A., & Galleni, M. (2013). The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction. PLoS ONE, 8 (9), 68014. doi:10.1371/journal.pone.0068014
Peer Reviewed verified by ORBi

Delbrück, H., Bogaerts, P., Kupper, M., Rezende de Castro, R., Bennik, S., Glupczynski, Y., Galleni, M., Hoffmann, K., & Bebrone, C. (November 2012). Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases. Antimicrobial Agents and Chemotherapy, 56(11), 5618-5625. doi:10.1128/AAC.01272-12
Peer Reviewed verified by ORBi

Laurent, C., Damblon, C., Hanikenne, M., & Galleni, M. (November 2012). Study of the structural factors that modulate the metal binding affinity of the N-terminal domain of the Arabidospsis halleri HMA4 [Poster presentation]. YBMRS 2012, Spa, Belgium.

Laurent, C., Hanikenne, M., & Galleni, M. (September 2012). Study of the structural factors that modulate the metal binding affinity of the Arabidopsis halleri HMA4 [Poster presentation]. Sofia School of Protein Science :Structure and dynamics of biological macromolecules, Sofia, Bulgaria.

Bouaziz, A., Campisi, V., Herman, J., Walgraffe, D., Jacquet, A., Hentges, F., Emmanuelle, A., Galleni, M., & Dumez, M.-E. (19 June 2012). Analysis of the allergenicity of natural and recombinant Der p 3 [Poster presentation]. 31éme congrès European Academy of allergy and Clinical Immunology, Genève, Switzerland.

Scarafone, N., Pain, C., Fratamico, A., Gaspard, G., yilmaz, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (March 2012). Amyloid-like fibril formation by polyQ proteins: a critical balance between the polyQ length and the constraints imposed by the host protein. PLoS ONE, 7 (3). doi:10.1371/journal.pone.0031253
Peer Reviewed verified by ORBi

Power, P., Mercuri, P., Herman, R., Kerff, F., Gutkind, G., Dive, G., Galleni, M., Charlier, P., & Sauvage, E. (2012). Novel fragments of clavulanate observed in the structure of the class A b-lactamase from Bacillus licheniformis BS3. Journal of Antimicrobial Chemotherapy, 67 (10), 2379-2387. doi:10.1093/jac/dks231
Peer Reviewed verified by ORBi

Moineaux, L., Laurent, S., Reniers, J., Dolusic, E., Galleni, M., Frère, J.-M., Masereel, B., Frederick, R., & Wouters, J. (2012). Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles. European Journal of Medicinal Chemistry, 54, 95-102. doi:10.1016/j.ejmech.2012.04.033
Peer Reviewed verified by ORBi

Ben Achour, N., Power, P., Mercuri, P., Ben Moussa, M., Galleni, M., & Belhadj, O. (2012). First detection of a transferable blaCTX-M-14b gene in a Klebsiella pneumoniae clinical isolate from Tunisia and analysis of its genetic context. Annals of Microbiology, 62, 1737-1742.
Peer Reviewed verified by ORBi

Delsaute, M., Berlemont, R., Bauvois, C., Wei, Q., Cornelis, P., & Galleni, M. (2012). Cellulase involvement in the bacterial cellulose biosynthesis [Poster presentation]. Biomedica 2012: Where Science and Business meet, Liège, Belgium.

Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinivasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2012). Allosteric inhibition of VIMs metallo-β-lactamases by a camelid single-domain antibody fragment [Poster presentation]. Biomedica 2012.

Baldo, A., Chevigné, A., Dumez, M.-E., Mathy, A., Power, P., Tabart, J., Cambier, L., Galleni, M., & Mignon, B. (2012). Inhibition of the keratinolytic subtilisin protease Sub3 from Microsporum canis by its propeptide (proSub3) and evaluation of the capacity of proSub3 to inhibit fungal adherence to feline epidermis. Veterinary Microbiology, 159 (3-4), 479-484. doi:10.1016/j.vetmic.2012.04.041
Peer Reviewed verified by ORBi

Kupper, M., Bauvois, C., Frère, J.-M., Galleni, M., & Bebrone, C. (January 2012). The CphAII protein from Aquifex aeolicus exhibits a metal-dependent phosphodiesterase activity. Extremophiles: Life Under Extreme Conditions, 16(1), 45-55. doi:10.1007/s00792-011-0404-1
Peer Reviewed verified by ORBi

Vandevenne, M., Galleni, M., & Filée, P. (2012). How to make good use of a “bad” enzyme: utilization of efficient β-lactamases for the benefits of biochemical research. In J.-M. Frère (Ed.), β-lactamases (pp. 479-503). Indiana, United States: Nova Science.
Peer reviewed

Laurent, C., Sohier, J., Pardon, E., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., Wyns, L., & Galleni, M. (10 December 2011). Characterization of the inhibition of metallo-β-lactamases of subclass B1 by VHHs cAbVIM4 and cAbBCII10 [Poster presentation]. journée doctorale SFMBBM, Liège, Belgium.

Laurent, C., Hanikenne, M., & Galleni, M. (14 October 2011). Insight into the structural factors that modulate the metal binding affinity of the Arabidospsis halleri HMA4 [Paper presentation]. SFMBBM graduate school 5th annual meeting, bruxelles, Belgium.

Laurent, C., Hanikenne, M., & Galleni, M. (14 October 2011). Insight into the structural factors that modulate the metal binding affinity of the Arabidospsis halleri HMA4 [Poster presentation]. SFMBBM graduate school 5th annual meeting, Bruxelles, Belgium.

El Garch, F., Bogaerts, P., Bebrone, C., Galleni, M., & Glupczynski, Y. (October 2011). OXA-198, an acquired carbapenem-hydrolyzing class D beta-lactamase from Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 55(10), 4828-4833. doi:10.1128/AAC.00522-11
Peer Reviewed verified by ORBi

Pain, C., Scarafone, N., Maruccia, C., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (27 August 2011). Generation of single-domain antidoby fragments raised against proteins containing polyglutamine expansions [Paper presentation]. Amyloid Fibrils, Prions and Precursors: Molecules for Targeted Intervention, Halle, Germany.

Horsfall, L., Izougarhane, Y., Lassaux, P., Selevsek, N., Liénard, B., Poirel, L., Kupper, M., Hoffmann, K., Frère, J.-M., Galleni, M., & Bebrone, C. (April 2011). Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme. FEBS Journal, 278(8), 1252-1263. doi:10.1111/j.1742-4658.2011.08046.x
Peer Reviewed verified by ORBi

Pain, C., Scarafone, N., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (25 January 2011). Generation of camelid single-domain antibody fragments raised against proteins containing polyglutamine expansions [Poster presentation]. Interuniversity Attraction Poles, Liège, Belgium.

Perez-Llarena, F. J., Kerff, F., Abian, O., Mallo, S., Fernandez, M. C., Galleni, M., Sancho, J., & Bou, G. (2011). Distant and new mutations in CTX-M-1 beta-lactamase affect cefotaxime hydrolysis. Antimicrobial Agents and Chemotherapy, 55 (9), 4361-8. doi:10.1128/AAC.00298-11
Peer Reviewed verified by ORBi

Bebrone, C., Delbrück, H., Kupper, M. B., Galleni, M., & Hoffmann, K. (2011). The structure of the C221D mutant of the subclass B2 CphA metallo-beta-lactamase shows a modification of the typical alpha beta beta alpha fold [Poster presentation]. 11th β-lactamase meeting, Leonessa, Italy.
Peer reviewed

Berlemont, R., Pipers, Delsaute, M., Angiono, F., Feller, G., Galleni, M., & Power, P. (2011). Exploring the Antarctic soil metagenome as a source of novel cold-adapted enzymes and genetic mobile elements. Revista Argentina de Microbiologia.
Peer Reviewed verified by ORBi

Vandevenne, M., Campisi, V., Freichels, A., Gillard, C., Gaspard, G., Frère, J.-M., Galleni, M., & Filée, P. (2011). Comparative functional analysis of the human macrophage chitotriosidase. Protein Science: A Publication of the Protein Society. doi:10.1002/pro.676
Peer Reviewed verified by ORBi

Bebrone, C., Kupper, M. B., Dehareng, D., Frère, J.-M., Hoffmann, K., & Galleni, M. (2011). The CphAII protein from Aquifex aeolicus possesses a metal-dependent phosphodiesterase activity [Poster presentation]. 11th β-lactamase meeting, Leonessa, Italy.
Peer reviewed

Bebrone, C., Delbrück, H., Kupper, M. B., Ervenich, D., Hoffmann, K., & Galleni, M. (2011). The C221D mutation leads to a modification of the Metallo-beta-Lactamase fold of CphA [Poster presentation]. IAP P6/19 project: PROFUSA meeting, Liège, Belgium.
Peer reviewed

Dolusic, E., Larrieu, P., Blanc, S., Sapunaric, F., Pouyez, J., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galleni, M., Frère, J.-M., Masereel, B., Van den Eynde, B., Wouters, J., & Frederick, R. (2011). Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. European Journal of Medicinal Chemistry, 46 (7), 3058-65. doi:10.1016/j.ejmech.2011.02.049
Peer Reviewed verified by ORBi

Dolusic, E., Larrieu, P., Blanc, S., Sapunaric, F., Norberg, B., Moineaux, L., Colette, D., Stroobant, V., Pilotte, L., Colau, D., Ferain, T., Fraser, G., Galleni, M., Frère, J.-M., Masereel, B., Van den Eynde, B., Wouters, J., & Frederick, R. (2011). Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. Bioorganic and Medicinal Chemistry, 19 (4), 1550-61. doi:10.1016/j.bmc.2010.12.032
Peer Reviewed verified by ORBi

Lassaux, P., Traoré, D., Loisel, E., Favier, A., Docquier, J.-D., Sohier, J., Laurent, C., Bebrone, C., Frère, J.-M., Ferrer, J.-L., & Galleni, M. (2011). Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01486-09
Peer Reviewed verified by ORBi

El Garch, F., Bogaerts, P., Bebrone, C., Galleni, M., & Glupczynski, G. (2011). Identification of OXA-198, a new carbapenem hydrolyzing class D beta-lactamase, in Pseudomonas aeruginosa [Poster presentation]. 21th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Milan, Italy.
Peer reviewed

Vandevenne, M., GASPARD, G., Belgsir, E. M., Ramnath, M., Cenatiempo, Y., Delneuville, D., Dumoulin, M., Frère, J.-M., Matagne, A., Galleni, M., & Filee, P. (2011). Effects of monopropanediamino-beta-cyclodextrin on the denaturation process of the hybrid protein BlaPChBD. Biochimica et Biophysica Acta. doi:10.1016/j.bbapap.2011.05.007
Peer Reviewed verified by ORBi

Delsaute, M., Berlemont, R., Paulus, V., Bauvois, C., Wei, Q., Cornelis, P., & Galleni, M. (2011). Cellulase involvement in the cellulose biosynthesis of Pseudomonas stutzeri [Poster presentation]. 13th International Conference on Pseudomonas, Sydney, Australia.

Pain, C., Scarafone, N., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (10 December 2010). Generation of camelid single-domain antibody fragments raised against proteins containing polyglutamine expansions [Poster presentation]. Journée des doctorants, Liège, Belgium.

Toncheva, N., Aqil, A., Croisier, F., Dijkstra, P., Feijen, J., van der Werf, K., Bennink, M., Galleni, M., Poumay, Y., Colige, A., & Jérôme, C. (29 November 2010). Chitosan nanofiber membranes for tissue engineering - synthesis, characterization and properties [Poster presentation]. PAI P6/27 Annual Meeting, Brussels, Belgium.

Vercheval, L., Di Paolo, A., Borel, F., Ferrer, J.-L., Sauvage, E., Matagne, A., Frère, J.-M., Charlier, P., Galleni, M., & Kerff, F. (25 November 2010). Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys 70. Biochemical Journal, 432 (3), 495-504. doi:10.1042/BJ20101122
Peer Reviewed verified by ORBi

Pain, C., Scarafone, N., Jaspar, A., Buys, N., Willibal, K., Filée, P., Galleni, M., Matagne, A., Steyaert, J., Pardon, E., & Dumoulin, M. (14 October 2010). Generation of camelid single-domain antibody fragments raised against proteins containing polyglutamine expansions [Poster presentation]. Single Domain Antibodies Come of Age, Ghent, Belgium.

Filée, P., Rhazi, N., Galleni, M., Taminiau, B., Jolois, O., Collard, A., & Jacquet, A. (22 July 2010). A recombinant alpha-hemolysin polypeptide of Staphylococcus aureus, having deletion in the stem domain and heterologous sequences inserted.

Scarafone, N., Pain, C., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (07 June 2010). Interplay between the effects of the length of the polyglutamine tract and its structural context on the aggregation of polyglutamine (polyQ) proteins [Poster presentation]. Conférence Jacques Monod : Protein misfolding and aggregation in ageing and disease, Roscoff, France.

Mallo, S., Pérez-Llarena, F. J., Kerff, F., Fernández-Moreira, E., Soares, N. C., Galleni, M., & Bou, G. (June 2010). A Tripeptide Deletion in the Class C beta-Lactamase FOX-4 Enzyme Impairs Cefoxitin Hydrolysis and Slightly Increases Susceptibility to beta-Lactamase Inhibitors. Journal of Antimicrobial Chemotherapy, 65 (6), 1187-94. doi:10.1093/jac/dkq115
Peer Reviewed verified by ORBi

Bebrone, C., Lassaux, P., Vercheval, L., Sohier, J., Jehaes, A., Sauvage, E., & Galleni, M. (16 April 2010). Current challenges in antimicrobial chemotherapy: focus on beta-lactamase inhibition. Drugs, 70(6), 651-679. doi:10.2165/11318430-000000000-00000
Peer Reviewed verified by ORBi

Berlemont, R., Delsaute, M., & Galleni, M. (22 March 2010). Insights into the metagenomic approach : identification and characterization of cellulases involved in bacterial cellulose synthesis [Paper presentation]. 239th American Chemical Society National Meeting & Exposition, San Francisco, United States - California.

Delsaute, M., Berlemont, R., Renson, T., & Galleni, M. (2010). Cellulase involvement in the cellulose biosynthesis [Poster presentation]. Journée doctorale SFMBBM, Liège, Belgium.

Lassaux, P., Hamel, M., Gulea, M., Delbrück, H., Mercuri, P., Horsfall, L., Dehareng, D., Kupper, M., Frère, J.-M., Hoffmann, K., Galleni, M., & Bebrone, C. (2010). Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-β-lactamases. Journal of Medicinal Chemistry, 53, 4862–4876. doi:10.1021/jm100213c
Peer Reviewed verified by ORBi

Geenen, V., Mottet, M., Dardenne, O., Kermani, H., Martens, H., François, J.-M., Galleni, M., Hober, D., Rahmouni, S., & Moutschen, M. (2010). Thymic self-antigens for the design of a negative/tolerogenic self-vaccination against type 1 diabetes. Current Opinion in Pharmacology, 10, 461-472. doi:10.1016/j.coph.2010.04.005
Peer Reviewed verified by ORBi

Delsaute, M., Berlemont, R., Renson, T., & Galleni, M. (2010). Cellulases catalysed cellulose polymerisation [Poster presentation]. 35th FEBS Congress: Molecules of Life, Göteborg, Sweden.

Baldo, A., Mathy, A., Tabart, J., Camponova, P., Vermout, S., Massart, L., Maréchal, F., Galleni, M., & Mignon, B. (2010). Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis. British Journal of Dermatology, 162 (5), 990-997. doi:10.1111/j.1365-2133.2009.09608.x
Peer Reviewed verified by ORBi

Sohier, J., Laurent, C., Pardon, E., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., Wyns, L., & Galleni, M. (2010). cAbVIM4, a nanobody inhibiting the metallo-β-lactamase VIM-4 [Poster presentation]. 35th FEBS Congress: Molecules of Life, Göteborg, Sweden.

Phichith, D., Bun, S., Padiolleau-Lefevre, S., Guellier, A., Banh, S., Galleni, M., Frère, J.-M., Thomas, D., Friboulet, A., & Avalle, B. (2010). Novel peptide inhibiting both TEM-1 beta-lactamase and penicillin-binding proteins. FEBS Journal, 277 (23), 4965-72. doi:10.1111/j.1742-4658.2010.07906.x
Peer Reviewed verified by ORBi

Berlemont, R., & Galleni, M. (2010). Carbohydrate actives enzymes derived from metagenomes: from microbial ecology to enzymology. In R. W. Li (Ed.), Metagenomics and its Applications in Agriculture, Biomedicine and Environmental Studies (1ère éd). New York, United States: NovaScience.

Chevigne, A., Dumez, M.-E., Dumoulin, M., Matagne, A., Jacquet, A., & Galleni, M. (2010). Comparative study of mature and zymogen mite cysteine protease stability and pH unfolding. Biochimica et Biophysica Acta, 1800 (9), 937-945. doi:10.1016/j.bbagen.2010.05.011
Peer Reviewed verified by ORBi

Lassaux, P., Delbrück, H., Gulea, M., Kupper, M., Hoffmann, K., Galleni, M., & Bebrone, C. (2010). Interactions mediating the positioning of mercapto-phosphonate inhibitors in the active site of metallo-beta-lactamases [Paper presentation]. ECCMID, Vienne, Austria.
Peer reviewed

Sohier, J., Laurent, C., Chevigné, A., Pardon, E., Srinvasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2010). Characterisation of B1 metallo-beta-lactamase inhibition by VHHs.

Sohier, J., Laurent, C., Pardon, E., Srinivasan, V., Lassaux, P., Buys, N., Willibal, K., Steyaert, J., & Galleni, M. (2010). CA1838, A NANOBODY INHIBITING THE METALLO-β-LACTAMASE VIM-4 [Poster presentation]. Single Domain Antibodies Come of Age.

Rodriguez, M. M., Power, P., Sader, H., Galleni, M., & Gutkind, G. (2010). Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. Antimicrobial Agents and Chemotherapy, 54 (7), 3070-1. doi:10.1128/AAC.01615-09
Peer Reviewed verified by ORBi

Minond, D., Saldanha, S. A., Spaargaren, M., Spicer, T., Fotsing, J. R., Weide, T., Fokin, V. V., Sharpless, K. B., Galleni, M., Bebrone, C., Lassaux, P., & Hodder, P. (15 July 2009). Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries. Bioorganic and Medicinal Chemistry, 17, 5027-37. doi:10.1016/j.bmc.2009.05.070
Peer Reviewed verified by ORBi

Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (28 April 2009). Effect of polyQ insertions on the structural, thermodynamic and aggregating properties of the beta-lactamase from B. Licheniformis 749/C (BlaP) [Poster presentation]. Conférence Jacques Monod : Protein folds in infectious and neurodegenerative diseases, Aussois, France.

Bebrone, C., Delbrück, H., Wilmann, C., Galleni, M., Frère, J.-M., & Hoffmann, K. (2009). The structure of the di-zinc form of the subclass B2 CphA metallo-β-lactamase reveals that the second zinc ion binds in the Histidine site [Poster presentation]. “Penicillin-recognizing enzymes: from enzyme kinetics to protein folding” symposium, Liège, Belgium.

Ben Achour, N., Mercuri, P., Ben Moussa, M., Galleni, M., & Belhadj, O. (2009). Characterization of a novel extended-spectrum TEM-type beta-lactamase, TEM-164, in a clinical strain of Klebsiella pneumoniae in Tunisia. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 15 (3), 195-9. doi:10.1089/mdr.2009.0900
Peer Reviewed verified by ORBi

Ben Achour, N., Mercuri, P., Power, P., Belhadj, C., Ben Moussa, M., Galleni, M., & Belhadj, O. (2009). First detection of CTX-M-28 in a Tunisian hospital from a cefotaxime-resistant Klebsiella pneumoniae strain. Pathologie Biologie, 57 (5), 343-8. doi:10.1016/j.patbio.2008.07.016
Peer Reviewed verified by ORBi

Berlemont, R., Delsaute, M., Pipers, D., D'Amico, S., Feller, G., Galleni, M., & Power, P. (2009). Insights into bacterial cellulose biosynthesis by functional metagenomics on Antarctic soil samples. ISME Journal, 3 (9), 1070-1081. doi:10.1038/ismej.2009.48
Peer Reviewed verified by ORBi

Bebrone, C., Delbrück, H., Kupper, M., Schlömer, P., Willmann, C., Frère, J.-M., Fisher, R., Galleni, M., & Hoffmann, K. (2009). The structure of the di-zinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the "histidine" site. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.00288-09
Peer Reviewed verified by ORBi

Gangoue Pieboji, J., Eze, N., Ngongang Djintchui, A., Ngameni, B., Tsabang, N., Pegnyemb, D. E., Biyiti, L., Ngassam, P., Koulla-Shiro, S., & Galleni, M. (2009). The in-vitro antimicrobial activity of some medicinal plants against beta-lactam-resistant bacteria. Journal of Infection in Developing Countries, 3 (9), 671-80. doi:10.3855/jidc.77
Peer Reviewed verified by ORBi

Baurin, S., Vercheval, L., Bouillenne, F., Falzone, C., Brans, A., Jacquamet, L., Ferrer, J.-L., Sauvage, E., Dehareng, D., Frère, J.-M., Charlier, P., Galleni, M., & Kerff, F. (2009). Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48 (47), 11252-63. doi:10.1021/bi901548c
Peer Reviewed verified by ORBi

Pellegrini, C., Mercuri, P., Celenza, G., Galleni, M., Segatore, B., Sacchetti, E., Volpe, R., Amicosante, G., & Perilli, M. (2009). Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location. Journal of Antimicrobial Chemotherapy, 63 (5), 901-8. doi:10.1093/jac/dkp061
Peer Reviewed verified by ORBi

Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (September 2008). Chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Poster presentation]. 20th Faltertage: Folding in vitro, folding in vivo and folding h.c, Wittenberg, Germany.

Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (September 2008). Chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Paper presentation]. 20th Faltertage: Folding in vitro, folding in vivo and folding h.c, Wittenberg, Germany.

Scarafone, N., Filée, Galleni, M., Matagne, A., & Dumoulin, M. (22 July 2008). Creation of chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Paper presentation]. 22nd Annual Symposium of The Protein Society, San Diego, United States.

Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (20 July 2008). Creation of chimeric proteins as models to study the mechanism of aggregation associated with polyglutamine expansions [Poster presentation]. 22nd Annual Symposium of The Protein Society, San Diego, United States.

Lenoir, S., Pagnoulle, C., Galleni, M., Compère, P., Jérôme, R., & Detrembleur, C. (22 May 2008). Polyolefin matrixes with permanent antibacterial activity: preparation, antibacterial activity, and action mode of the active species [Poster presentation]. Belgian Polymer Group (BPG) annual meeting 2008, De Haan, Belgium.

Vandevenne, M., Gaspard, G., Yilmaz, N., Giannotta, F., Frère, J.-M., Galleni, M., & Filée, P. (2008). Rapid and easy development of versatile tools to study protein/ligand interactions. Protein Engineering, Design and Selection. doi:10.1093/protein/gzn021
Peer Reviewed verified by ORBi

Bebrone, C., Delbrück, H., Kupper, M. B., Galleni, M., Frère, J.-M., & Hoffmann, K. (2008). The structure of the di-zinc form of the subclass B2 CphA metallo-β-lactamase reveals that the second zinc binds in the Histidine site [Poster presentation]. International congress on Biocatalysis BIOCAT, Hambourg, Germany.
Peer reviewed

Lienard, B. M. R., Garau, G., Horsfall, L., Karsisiotis, A. I., Damblon, C., Lassaux, P., Papamicael, C., Roberts, G. C. K., Galleni, M., Dideberg, O., Frère, J.-M., & Schofield, C. J. (2008). Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. Organic and Biomolecular Chemistry, 6 (13), 2282-2294. doi:10.1039/b802311e
Peer Reviewed verified by ORBi

Ben Achour, N., Mercuri, P., Belhadj, C., Ben Moussa, M., Galleni, M., & Belhadj, O. (2008). Cefotaxime and ceftriaxon resistant Klebsiella pneumoniae associated with SHV-11 hyperproduction. Annals of Microbiology, 5 (4), 727-730. doi:10.1007/BF03175582
Peer Reviewed verified by ORBi

Lienard, B. M. R., Huting, R., Lassaux, P., Galleni, M., Frère, J.-M., & Schofield, C. J. (2008). Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors. Journal of Medicinal Chemistry, 51 (3), 684-8. doi:10.1021/jm070866g
Peer Reviewed verified by ORBi

Ruth, N., Quinting, B., Mainil, J., Hallet, B., Frère, J.-M., Huygen, K., & Galleni, M. (2008). Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A beta-lactamase. FEBS Journal, 275, 5151-5160. doi:10.1111/j.1742-4658.2008.06646.x
Peer Reviewed verified by ORBi

Javaux, E., Claeys, P., Dehant, V., Galleni, M., Reisse, J., Wilmotte, A., & Nazé, Y. (2008). Astrobiologie. (Geol0263-1, Geol0263-2).

Dumez, M.-E., Teller, N., Mercier, F., Tanaka, T., Vandenberghe, I., Vandenbranden, M., Devreese, B., Luxen, A., Frère, J.-M., Matagne, A., Jacquet, A., Galleni, M., & Chevigne, A. (2008). Activation mechanism of recombinant Der p 3 allergen zymogen - Contribution of cysteine protease Der p 1 and effect of propeptide glycosylation. Journal of Biological Chemistry, 283 (45), 30606-30617. doi:10.1074/jbc.M803041200
Peer Reviewed verified by ORBi

Shimizu-Ibuka, A., Bauvois, C., Sakai, H., & Galleni, M. (2008). Structure of the plasmid-mediated class C beta-lactamase ACT-1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 64 (Pt 5), 334-7. doi:10.1107/S1744309108008531
Peer Reviewed verified by ORBi

Pipers, D., Berlemont, R., Power, P., Collins, T., Feller, G., & Galleni, M. (2008). Isolation of novel hydrolytic genes from an Antarctic metagenomic library [Poster presentation]. 3rd International Conference on Polar and Alpine Microbiology, Banff, Canada.

Zervosen, A., Saegerman, C., Antoniotti, I., Robert, B., Ruth, N., Collard, A., Schynts, F., Galleni, M., & Mercuri, P. (2008). Characterization of the cattle serum antibody responses against TEM beta-lactamase and the nonimmunogenic Escherichia coli heat-stable enterotoxin (STaI). FEMS Immunology and Medical Microbiology, 54 (3), 319-329. doi:10.1111/j.1574-695X.2008.00482.x
Peer Reviewed verified by ORBi

Bebrone, C., Anne, C., Kerff, F., Garau, G., De Vriendt, K., Lantin, R., Devreese, B., Van Beeumen, J., Dideberg, O., Frère, J.-M., & Galleni, M. (2008). Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila. Biochemical Journal, 414 (1), 151-9. doi:10.1042/BJ20080375
Peer Reviewed verified by ORBi

Chevigné, A., Barumandzadeh, R., Groslambert, S., Cloes, B., Dehareng, D., Filée, P., Marx, J.-C., Frère, J.-M., Matagne, A., Jacquet, A., & Galleni, M. (16 November 2007). Relationship between propeptide pH unfolding and inhibitory ability during ProDer p 1 activation mechanism. Journal of Molecular Biology, 374 (1), 170-185. doi:10.1016/j.jmb.2007.08.025
Peer Reviewed verified by ORBi

Lebrun, M., Filée, P., Galleni, M., Mainil, J., Linden, A., & Taminiau, B. (September 2007). Purification of the recombinant beta2 toxin (CPB2) from an enterotoxaemic bovine Clostridium perfringens strain and production of a specific immune serum. Protein Expression and Purification, 55 (1), 119-131. doi:10.1016/j.pep.2007.04.021
Peer Reviewed verified by ORBi

Faure, E., Halusiak, E., Ruth, N., Gabriel, S., Filée, P., Giannotta, F., Frère, J.-M., Galleni, M., Jérôme, C., & Jérôme, R. (31 August 2007). Biosensors based on electrochemically prepared polyanilines and bifunctional hybrid proteins [Poster presentation]. Polymers: Last achievements and prospects, in honour of Professor Jérôme, Liège, Belgium.

Horsfall, L. E., Garau, G., Lienard, B. M., Dideberg, O., Schofield, C. J., Frere, J. A., & Galleni, M. (June 2007). Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila. Antimicrobial Agents and Chemotherapy, 51 (6), 2136-2142. doi:10.1128/AAC.00866-06
Peer Reviewed verified by ORBi

Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (May 2007). Creation of chimeric proteins as models to study the mechanism of aggregation of proteins with expanded polyglutamine repeats [Poster presentation]. VII European Symposium of The Protein Society, Stockholm-Uppsala, Sweden.

Cornaglia, G., Akova, M., Amicosante, G., Canton, R., Cauda, R., Docquier, J.-D., Edelstein, M., Frère, J.-M., Fuzi, M., Galleni, M., Giamarellou, H., Gniadkowski, M., Koncan, R., Libisch, B., Luzzaro, F., Miriagou, V., Navarro, F., Nordmann, P., Pagani, L., ... Rossolini, G. M. (April 2007). Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues. International Journal of Antimicrobial Agents, 29 (4), 380-388. doi:10.1016/j.ijantimicag.2006.10.008
Peer Reviewed verified by ORBi

Chevigné, A., Yilmaz, N., Gaspard, G., Giannotta, F., François, J.-M., Frère, J.-M., Galleni, M., & Filée, P. (30 March 2007). Use of bifunctional hybrid beta-lactamases for epitope mapping and immunoassay development. Journal of Immunological Methods, 320 (1-2), 81-93. doi:10.1016/j.jim.2006.12.009
Peer Reviewed verified by ORBi

Rodriguez, M. M., Power, P., Bauvois, C., Di Conza, J., Ayala, J. A., Galleni, M., & Gutkind, G. (March 2007). Characterisation of KLUA-9, a beta-lactamase from extended-spectrum cephalosporin-susceptible Kluyvera ascorbata, and genetic organisation of bla(KLUA-9). International Journal of Antimicrobial Agents, 29 (3), 332-337. doi:10.1016/j.ijantimicag.2006.09.015
Peer Reviewed verified by ORBi

Lienard, B. M. R., Horsfall, L. E., Galleni, M., Frère, J.-M., & Schofield, C. J. (15 February 2007). Inhibitors of the FEZ-1 metallo-beta-lactamase. Bioorganic and Medicinal Chemistry Letters, 17 (4), 964-968. doi:10.1016/j.bmcl.2006.11.053
Peer Reviewed verified by ORBi

Ishii, Y., Galleni, M., Ma, L., Frère, J.-M., & Yamaguchi, K. (February 2007). Biochemical characterisation of the CTX-M-14 beta-lactamase. International Journal of Antimicrobial Agents, 29 (2), 159-164. doi:10.1016/j.ijantimicag.2006.09.005
Peer Reviewed verified by ORBi

Vandevenne, M., Filée, P., Scarafone, N., Cloes, B., Gaspard, G., Yilmaz, N., Dumoulin, M., François, J.-M., Frère, J.-M., & Galleni, M. (2007). The Bacillus licheniformis BlaP beta-lactamase as a model protein scaffold to study the insertion of protein fragments. Protein Science: A Publication of the Protein Society, 16 (10), 2260-71. doi:10.1110/ps.072912407
Peer Reviewed verified by ORBi

Lebrun, M., Filée, P., Mousset, B., Desmecht, D., Galleni, M., Mainil, J., & Linden, A. (2007). The expression of Clostridium perfringens consensus beta2 toxin is associated with bovine enterotoxaemia syndrome. Veterinary Microbiology, 120 (1-2), 151-157. doi:10.1016/j.vetmic.2006.10.020
Peer Reviewed verified by ORBi

Scarafone, N., Filée, P., Galleni, M., Matagne, A., & Dumoulin, M. (2007). Creation of chimeric proteins as models to study the mechanism of aggregation of proteins with expanded polyglutamine repeats [Poster presentation]. Joint Meeting of the Belgian Physical Society and the Belgian Biophysical Society, Antwerpen, Belgium.

Lassaux, P., Hamel, M., Gulea, M., Mercuri, P., Horsfall, L., Bebrone, C., Gaumont, A.-C., Frère, J.-M., & Galleni, M. (2007). Mercapto-phosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases. International Journal of Antimicrobial Agents, 29 (Supplément 2), 95.
Peer Reviewed verified by ORBi

Gangoue Pieboji, J., Baurin, S., Frère, J.-M., Ngassam, P., Ngameni, B., Azebaze, A., Pegnyemb, D. E., Watchueng, J., Goffin, C., & Galleni, M. (2007). Screening of some medicinal plants from cameroon for beta-lactamase inhibitory activity. Phytotherapy Research, 21 (3), 284-7. doi:10.1002/ptr.2001
Peer Reviewed verified by ORBi

Scarafone, N., Filée, P., Galleni, M., Dumoulin, M., & Matagne, A. (December 2006). Creation of chimeric proteins as models to study the mechanism of aggregation of polyglutamine proteins [Poster presentation]. Young scientists day, 194th Meeting of the Belgian Society of Biochemistry and Molecular Biology, and International Franqui Chair 2005/2006, Gembloux, Belgium.

Giannotta, Filée, P., Galleni, M., Frère, J.-M., Joris, B., Brans, A., & Ruth, N. (25 October 2006). Hybrid proteins of active-site serine beta-lactamase.

chouchani, C., Berlemont, R., masmoudi, A., Galleni, M., Frère, J.-M., belhadj, O., & ben-mahrez, K. (September 2006). A novel extended-spectrum TEM-type beta-lactamase, TEM-138, from Salmonella enterica serovar Infantis. Antimicrobial Agents and Chemotherapy, 50 (9), 3183-5. doi:10.1128/AAC.00388-06
Peer Reviewed verified by ORBi

Lenoir, S., Pagnoulle, C., Galleni, M., Compère, P., Jérôme, R., & Detrembleur, C. (August 2006). Polyolefin matrixes with permanent antibacterial activity : preparation, antibacterial activity, and action mode of the active species. Biomacromolecules, 7 (8), 2291-2296. doi:10.1021/bm050850c
Peer Reviewed verified by ORBi

Power, P., Galleni, M., Ayala, J. A., & Gutkind, G. (March 2006). Biochemical and molecular characterization of three new variants of AmpC beta-lactamases from Morganella morganii. Antimicrobial Agents and Chemotherapy, 50 (3), 962-967. doi:10.1128/AAC.50.3.962-967.2006
Peer Reviewed verified by ORBi

Lenoir, S., Pagnoulle, C., Detrembleur, C., Galleni, M., & Jérôme, R. (01 February 2006). New antibacterial cationic surfactants prepared by Atom Transfer Radical Polymerization. Journal of Polymer Science. Part A, Polymer Chemistry, 44 (3), 1214-1224. doi:10.1002/pola.21229
Peer Reviewed verified by ORBi

De Vriendt, K., Van Driessche, G., Devreese, B., Bebrone, C., Anne, C., Frère, J.-M., Galleni, M., & Van Beeumen, J. (February 2006). Monitoring the zinc affinity of the metallo-beta-lactamase CphA by automated nanoESI-MS. Journal of the American Society for Mass Spectrometry, 17 (2), 180-188. doi:10.1016/j.jasms.2005.10.007
Peer Reviewed verified by ORBi

Sauvage, E., Fonze, E., Quinting, B., Galleni, M., Frère, J.-M., & Charlier, P. (2006). Crystal structure of the Mycobacterium fortuitum class A beta-lactamase: structural basis for broad substrate specificity. Antimicrobial Agents and Chemotherapy, 50 (7), 2516-21. doi:10.1128/AAC.01226-05
Peer Reviewed verified by ORBi

Lenoir, S., Pagnoulle, C., Detrembleur, C., Galleni, M., & Jérôme, R. (26 October 2005). Antimicrobial activity of polyestyrene particles coated by photo-crooslinked block copolymers containing a biocidal polymethacrylate block. e-Polymers, 74, 1-11.
Peer Reviewed verified by ORBi

Piette, A., Derouaux, A., Gerkens, P., Noens, E. E. E., Mazzucchelli, G., Vion, S., Koerten, H. K., Titgemeyer, F., De Pauw, E., Leprince, P., van Wezel, G. P., Galleni, M., & Rigali, S. (September 2005). From dormant to germinating spores of Streptomyces coelicolor A3(2): new perspectives from the crp null mutant. Journal of Proteome Research, 4 (5), 1699-708. doi:10.1021/pr050155b
Peer Reviewed verified by ORBi

Bebrone, C., Anne, C., De Vriendt, K., Devreese, B., Rossolini, G. M., Van Beeumen, J., Frère, J.-M., & Galleni, M. (05 August 2005). Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis. Journal of Biological Chemistry, 280 (31), 28195-28202. doi:10.1074/jbc.M414052200
Peer Reviewed verified by ORBi

Lenoir, S., Pagnoulle, C., Detrembleur, C., Galleni, M., & Jérôme, R. (01 June 2005). ATRP of aminated methacrylates: a route to effective antimicrobial surfactants, coatings and additives [Paper presentation]. Advanced nanomaterials for biofunctional surfaces, Liège, Belgium.

Lenoir, S., Pagnoulle, C., Galleni, M., & Jérôme, R. (19 May 2005). ATRP of aminated methacrylates: a route to effective antimicrobial surfactants, coatings and additives [Paper presentation]. Belgian Polymer Group (BPG) annual meeting 2005, La Roche en Ardenne, Belgium.

Ruth, N., Mainil, J., Roupie, V., Frère, J.-M., Galleni, M., & Huygen, K. (May 2005). DNA vaccination for the priming of neutralizing antibodies against non-immunogenic STa enterotoxin from enterotoxigenic Escherichia coli. Vaccine, 23 (27), 3618-3627. doi:10.1016/j.vaccine.2004.11.080
Peer Reviewed verified by ORBi

Garau, G., Bebrone, C., Anne, C., Galleni, M., Frère, J.-M., & Dideberg, O. (28 January 2005). A metallo-beta-lactamase enzyme in action: Crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. Journal of Molecular Biology, 345 (4), 785-795. doi:10.1016/j.jmb.2004.10.070
Peer Reviewed verified by ORBi

Bauvois, C., Ibuka, A. S., Celso, A., Alba, J., Ishii, Y., Frère, J.-M., & Galleni, M. (2005). Kinetic properties of four plasmid-mediated AmpC beta-lactamases. Antimicrobial Agents and Chemotherapy, 49 (10), 4240-6. doi:10.1128/AAC.49.10.4240-4246.2005
Peer Reviewed verified by ORBi

Douette, P., Navet, R., Gerkens, P., Galleni, M., Lévy, D., & Sluse, F. (2005). Escherichia coli fusion carrier proteins act as solubilizing agents for recombinant uncoupling protein 1 through interactions with GroEL. Biochemical and Biophysical Research Communications, 333, 686-693. doi:10.1016/j.bbrc.2005.05.164
Peer reviewed

Power, P., Galleni, M., Di Conza, J., Ayala, J., & Gutkind, G. (2005). Description of In116, the first blaCTX-M-2-containing complex class 1 integron found in Morganella morganii isolates from Buenos Aires, Argentina. Journal of Antimicrobial Chemotherapy, 55 (4), 461-465. doi:10.1093/jac/dkh556
Peer Reviewed verified by ORBi

Frère, J.-M., Galleni, M., Bush, K., & Dideberg, O. (2005). Is it necessary to change the classification of ß-lactamases? Journal of Antimicrobial Chemotherapy, 55 (6), 1051-1053. doi:10.1093/jac/dki155
Peer Reviewed verified by ORBi

Rodriguez, M. M., Power, P., Radice, M., Vay, C., Famiglietti, A., Galleni, M., Ayala, J. A., & Gutkind, G. (December 2004). Chromosome-encoded CTX-M-3 from Kluyvera ascorbata: a possible origin of plasmid-borne CTX-M-1-derived cefotaximases. Antimicrobial Agents and Chemotherapy, 48 (12), 4895-4897. doi:10.1128/AAC.48.12.4895-4897.2004
Peer Reviewed verified by ORBi

Ignatova, M., Voccia, S., Gilbert, B., Markova, N., Mercuri, P., Galleni, M., Sciannamea, V., Lenoir, S., Cossement, D., Gouttebaron, R., Jérôme, R., & Jérôme, C. (23 November 2004). Synthesis of copolymer brushes endowed with adhesion to stainless steel surfaces and antibacterial properties by controlled nitroxide-mediated radical polymerization. Langmuir, 20 (24), 10718-10726. doi:10.1021/la048347t
Peer Reviewed verified by ORBi

Mercuri, P., Garcia-Saez, I., De Vriendt, K., Thamm, I., Devreese, B., Van Beeumen, J., Dideberg, O., Rossolini, G. M., Frère, J.-M., & Galleni, M. (06 August 2004). Probing the specificity of the subclass B3 FEZ-1 metallo-beta-lactamase by site-directed mutagenesis. Journal of Biological Chemistry, 279 (32), 33630-33638. doi:10.1074/jbc.M403671200
Peer Reviewed verified by ORBi

Garau, G., Garcia-Saez, I., Bebrone, C., Anne, C., Mercuri, P., Galleni, M., Frère, J.-M., & Dideberg, O. (July 2004). Update of the standard numbering scheme for class B beta-lactamases. Antimicrobial Agents and Chemotherapy, 48 (7), 2347-2349. doi:10.1128/AAC.48.7.2347-2349.2004
Peer Reviewed verified by ORBi

Tsang, W. Y., Dhanda, A., Schofield, C. J., Frère, J.-M., Galleni, M., & Page, M. I. (05 April 2004). The inhibition of metallo-beta-lactamase by thioxo-cephalosporin derivatives. Bioorganic and Medicinal Chemistry Letters, 14 (7), 1737-1739. doi:10.1016/j.bmcl.2004.01.047
Peer Reviewed verified by ORBi

Gérard, S., Galleni, M., Dive, G., & Marchand-Brynaert, J. (02 January 2004). Synthesis and evaluation of N1/C4-substituted beta-lactams as PPE and HLE inhibitors. Bioorganic and Medicinal Chemistry, 12 (1), 129-138. doi:10.1016/j.bmc.2003.10.009
Peer Reviewed verified by ORBi

Ibuka, A. S., Ishii, Y., Galleni, M., Ishiguro, M., Yamaguchi, K., Frère, J.-M., Matsuzawa, H., & Sakai, H. (16 September 2003). Crystal structure of extended-spectrum beta-lactamase Toho-1: Insights into the molecular mechanism for catalytic reaction and substrate specificity expansion. Biochemistry, 42 (36), 10634-10643. doi:10.1021/bi0342822
Peer Reviewed verified by ORBi

Alba, J., Bauvois, C., Ishii, Y., Galleni, M., Masuda, K., Ishiguro, M., Ito, M., Frère, J.-M., & Yamaguchi, K. (29 August 2003). A detailed kinetic study of Mox-1, a plasmid-encoded class C beta-lactamase. FEMS Microbiology Letters, 225 (2), 183-188. doi:10.1016/S0378-1097(03)00448-8
Peer Reviewed verified by ORBi

Garcia-Saez, I., Hopkins, J., Papamicael, C., Franceschini, N., Amicosante, G., Rossolini, G. M., Galleni, M., Frère, J.-M., & Dideberg, O. (27 June 2003). The 1.5-angstrom structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril. Journal of Biological Chemistry, 278 (26), 23868-23873.
Peer Reviewed verified by ORBi

Moali, C., Anne, C., Lamotte-Brasseur, J., Groslambert, S., Devreese, B., Van Beeumen, J., Galleni, M., & Frère, J.-M. (April 2003). Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis. Chemistry and Biology, 10 (4), 319-329. doi:10.1016/S1074-5521(03)00070-X
Peer Reviewed verified by ORBi

Docquier, J.-D., Lamotte-Brasseur, J., Galleni, M., Amicosante, G., Frère, J.-M., & Rossolini, G. M. (February 2003). On functional and structural heterogeneity of VIM-type metallo-beta-lactamases. Journal of Antimicrobial Chemotherapy, 51 (2), 257-266. doi:10.1093/jac/dkg067
Peer Reviewed verified by ORBi

Garcia-Saez, I., Mercuri, P., Papamicael, C., Kahn, R., Frère, J.-M., Galleni, M., Rossolini, G. M., & Dideberg, O. (24 January 2003). Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril. Journal of Molecular Biology, 325 (4), 651-660. doi:10.1016/S0022-2836(02)01271-8
Peer Reviewed verified by ORBi

Bebrone, C., Anne, C., & Galleni, M. (2003). Modification of the specificity of the CphA metallo- β-lactamase produced by Aeromonas hydrophila by site-directed mutagenesis [Poster presentation]. Bioforum, Liège, Belgium.

Vanhove, M., Zakhem, M., Devreese, B., Franceschini, N., Anne, C., Bebrone, C., Amicosante, G., Rossolini, G. M., Van Beeumen, J., Frère, J.-M., & Galleni, M. (2003). Role of Cys221 and Asn116 in the zinc-binding sites of the Aeromonas hydrophila metallo-beta-lactamase. Cellular and Molecular Life Sciences, 60 (11), 2501-9. doi:10.1007/s00018-003-3092-x
Peer Reviewed verified by ORBi

Prosperi, C., De Seny, D., Llabres, G., Galleni, M., & Lamotte-Brasseur, J. (December 2002). Active-site mutants of class B beta-lactamases: substrate binding and mechanistic study. Cellular and Molecular Life Sciences, 59 (12), 2136-2143. doi:10.1007/s000180200013
Peer Reviewed verified by ORBi

Wommer, S., Rival, S., Heinz, U., Galleni, M., Frère, J.-M., Franceschini, N., Amicosante, G., Rasmussen, B., Bauer, R., & Adolph, H. W. (05 July 2002). Substrate-activated zinc binding of metallo-beta-lactamases - Physiological importance of the mononuclear enzymes. Journal of Biological Chemistry, 277 (27), 24142-24147. doi:10.1074/jbc.M202467200
Peer Reviewed verified by ORBi

Vessillier, S., Docquier, J.-D., Rival, S., Frère, J.-M., Galleni, M., Amicosante, G., Rossolini, G. M., & Franceschini, N. (June 2002). Overproduction and biochemical characterization of the Chryseobacterium meningosepticum BlaB metallo-beta-lactamase. Antimicrobial Agents and Chemotherapy, 46 (6), 1921-1927. doi:10.1128/AAC.46.6.1921-1927.2002
Peer Reviewed verified by ORBi

Docquier, J.-D., Pantanella, F., Giuliani, F., Thaller, M. C., Amicosante, G., Galleni, M., Frère, J.-M., Bush, K., & Rossolini, G. M. (June 2002). CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome. Antimicrobial Agents and Chemotherapy, 46 (6), 1823-1830. doi:10.1128/AAC.46.6.1823-1830.2002
Peer Reviewed verified by ORBi

De Seny, D., Prosperi, C., Bebrone, C., Rossolini, G. M., Page, M. I., Noel, P., Frère, J.-M., & Galleni, M. (01 May 2002). Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase. Biochemical Journal, 363 (Pt 3), 687-696. doi:10.1042/bj3630687
Peer Reviewed verified by ORBi

Mercuri, P., Ishii, Y., Ma, L., Rossolini, G. M., Luzzaro, F., Amicosante, G., Franceschini, N., Frère, J.-M., & Galleni, M. (2002). Clonal diversity and metallo-beta-lactamase production in clinical isolates of Stenotrophomonas maltophilia. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 8 (3), 193-200. doi:10.1089/107662902760326904
Peer Reviewed verified by ORBi

Matagne, A., Galleni, M., Laraki, N., Amicosante, G., Rossolini, G., & Frère, J.-M. (2002). Beta-lactamases, an old but ever renascent problem. In A. van Broekhoven (Ed.), Novel Frontiers in the Production of Compounds for Biomedical Use. Dordrecht, Netherlands: Kluwer Academic Publishers.
Peer reviewed

Bebrone, C., Anne, C., & Galleni, M. (2002). Molecular evolution of the Aeromonas hydrophila CphA metallo-β-lactamase [Poster presentation]. Engineering enzymes for biocatalysis by using directed evolution, Paris, France.
Peer reviewed

De Seny, D., Heinz, U., Wommer, S., Kiefer, M., Meyer-Klaucke, W., Galleni, M., Frère, J.-M., Bauer, R., & Adolph, H. W. (30 November 2001). Metal Ion Binding and Coordination Geometry for Wild Type and Mutants of Metallo-Beta -Lactamase from Bacillus Cereus 569/H/9 (Bcii): A Combined Thermodynamic, Kinetic, and Spectroscopic Approach. Journal of Biological Chemistry, 276 (48), 45065-78. doi:10.1074/jbc.M106447200
Peer Reviewed verified by ORBi

Vilar, M., Galleni, M., Solmajer, T., Turk, B., Frère, J.-M., & Matagne, A. (August 2001). Kinetic Study of Two Novel Enantiomeric Tricyclic Beta-Lactams Which Efficiently Inactivate Class C Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (8), 2215-23. doi:10.1128/AAC.45.8.2215-2223.2001
Peer Reviewed verified by ORBi

Zervosen, A., Valladares, M. H., Devreese, B., Prosperi, C., Adolph, H.-W., Mercuri, P., Vanhove, M., Amicosante, G., van Beeumen, J., Frère, J.-M., & Galleni, M. (July 2001). Inactivation of Aeromonas Hydrophila Metallo-Beta-Lactamase by Cephamycins and Moxalactam. European Journal of Biochemistry, 268 (13), 3840-50. doi:10.1046/j.1432-1327.2001.02298.x
Peer Reviewed verified by ORBi

Bebrone, C., Moali, C., Mahy, F., Rival, S., Docquier, J.-D., Rossolini, G. M., Fastrez, J., Pratt, R. F., Frère, J.-M., & Galleni, M. (June 2001). Centa as a Chromogenic Substrate for Studying Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (6), 1868-71. doi:10.1128/AAC.45.6.1868-1871.2001
Peer Reviewed verified by ORBi

Mercuri, P., Bouillenne, F., Boschi, L., Lamotte-Brasseur, J., Amicosante, G., Devreese, B., van Beeumen, J., Frère, J.-M., Rossolini, G. M., & Galleni, M. (April 2001). Biochemical Characterization of the Fez-1 Metallo-Beta-Lactamase of Legionella Gormanii Atcc 33297t Produced in Escherichia Coli. Antimicrobial Agents and Chemotherapy, 45 (4), 1254-62. doi:10.1128/AAC.45.4.1254-1262.2001
Peer Reviewed verified by ORBi

Galleni, M., Lamotte-Brasseur, J., Rossolini, G. M., Spencer, J., Dideberg, O., & Frère, J.-M. (March 2001). Standard Numbering Scheme for Class B Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (3), 660-3. doi:10.1128/AAC.45.3.660-663.2001
Peer Reviewed verified by ORBi

Bounaga, S., Galleni, M., Laws, A. P., & Page, M. I. (2001). Cysteinyl peptide inhibitors of Bacillus cereus zinc beta-lactamase. Bioorganic and Medicinal Chemistry, 9 (2), 503-10. doi:10.1016/S0968-0896(00)00257-1
Peer Reviewed verified by ORBi

Mollard, C., Moali, C., Papamicael, C., Damblon, C., Vessilier, S., Amicosante, G., Schofield, C. J., Galleni, M., Frère, J.-M., & Roberts, G. C. (2001). Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. Journal of Biological Chemistry, 276 (48), 45015-23. doi:10.1074/jbc.M107054200
Peer Reviewed verified by ORBi

Bebrone, C., Fastrez, J., Frère, J.-M., & Galleni, M. (2001). Centa as a chromogenic substrate for the study of β-lactamases [Poster presentation]. Bioforum, Liège, Belgium.

Franceschini, N., Boschi, L., Pollini, S., Herman, R., Perilli, M., Galleni, M., Frère, J.-M., Amicosante, G., & Rossolini, G. M. (2001). Characterization of OXA-29 from Legionella (Fluoribacter) gormanii: molecular class D beta-lactamase with unusual properties. Antimicrobial Agents and Chemotherapy, 45 (12), 3509-16. doi:10.1128/AAC.45.12.3509-3516.2001
Peer Reviewed verified by ORBi

Conrath, K. E., Lauwereys, M., Galleni, M., Matagne, A., Frère, J.-M., Kinne, J., Wyns, L., & Muyldermans, S. (2001). Beta-lactamase inhibitors derived from single-domain antibody fragments elicited in the camelidae. Antimicrobial Agents and Chemotherapy, 45 (10), 2807-12. doi:10.1128/AAC.45.10.2807-2812.2001
Peer Reviewed verified by ORBi

Concha, N. O., Janson, C. A., Rowling, P., Pearson, S., Cheever, C. A., Clarke, B. P., Lewis, C., Galleni, M., Frère, J.-M., Payne, D. J., Bateson, J. H., & Abdel-Meguid, S. S. (2000). Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor. Biochemistry, 39 (15), 4288-98. doi:10.1021/bi992569m
Peer Reviewed verified by ORBi

Hernandez Valladares, M., Kiefer, M., Heinz, U., Soto, R. P., Meyer-Klaucke, W., Nolting, H. F., Zeppezauer, M., Galleni, M., Frère, J.-M., Rossolini, G. M., Amicosante, G., & Adolph, H. W. (2000). Kinetic and spectroscopic characterization of native and metal-substituted beta-lactamase from Aeromonas hydrophila AE036. FEBS Letters, 467 (2-3), 221-5. doi:10.1016/S0014-5793(00)01102-9
Peer Reviewed verified by ORBi

Boschi, L., Mercuri, P., Riccio, M. L., Amicosante, G., Galleni, M., Frère, J.-M., & Rossolini, G. M. (2000). The Legionella (Fluoribacter) gormanii metallo-beta-lactamase: a new member of the highly divergent lineage of molecular-subclass B3 beta-lactamases. Antimicrobial Agents and Chemotherapy, 44 (6), 1538-43. doi:10.1128/AAC.44.6.1538-1543.2000
Peer Reviewed verified by ORBi

Chantalat, L., Duee, E., Galleni, M., Frère, J.-M., & Dideberg, O. (2000). Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase. Protein Science: A Publication of the Protein Society, 9 (7), 1402-6. doi:10.1110/ps.9.7.1402
Peer Reviewed verified by ORBi

Franceschini, N., Caravelli, B., Docquier, J.-D., Galleni, M., Frère, J.-M., Amicosante, G., & Rossolini, G. M. (2000). Purification and biochemical characterization of the VIM-1 metallo-beta-lactamase. Antimicrobial Agents and Chemotherapy, 44 (11), 3003-7. doi:10.1128/AAC.44.11.3003-3007.2000
Peer Reviewed verified by ORBi

Rhazi, N., Galleni, M., Page, M. I., & Frère, J.-M. (15 July 1999). Peptidase Activity of Beta-Lactamases. Biochemical Journal, 341 ((Pt 2)), 409-13. doi:10.1042/0264-6021:3410409
Peer Reviewed verified by ORBi

Laraki, N., Galleni, M., Thamm, I., Riccio, M. L., Amicosante, G., Frère, J.-M., & Rossolini, G. M. (April 1999). Structure of In31, a Blaimp-Containing Pseudomonas Aeruginosa Integron Phyletically Related to In5, Which Carries an Unusual Array of Gene Cassettes. Antimicrobial Agents and Chemotherapy, 43 (4), 890-901. doi:10.1128/aac.43.4.890
Peer Reviewed verified by ORBi

Matagne, A., Dubus, A., Galleni, M., & Frère, J.-M. (February 1999). The Beta-Lactamase Cycle: A Tale of Selective Pressure and Bacterial Ingenuity. Natural Product Reports, 16 (1), 1-19. doi:10.1039/a705983c
Peer Reviewed verified by ORBi

Frère, J.-M., Dubus, A., Galleni, M., Matagne, A., & Amicosante, G. (February 1999). Mechanistic Diversity of Beta-Lactamases. Biochemical Society Transactions, 27 (2), 58-63. doi:10.1042/bst0270058
Peer Reviewed verified by ORBi

Prosperi, C., Llabres, G., De Seny, D., Soto, R. P., Valladares, M. H., Laraki, N., Frère, J.-M., & Galleni, M. (25 January 1999). Interaction between Class B Beta-Lactamases and Suicide Substrates of Active-Site Serine Beta-Lactamases. FEBS Letters, 443 (2), 109-11. doi:10.1016/S0014-5793(98)01689-5
Peer Reviewed verified by ORBi

Laraki, N., Franceschini, N., Rossolini, G. M., Santucci, P., Meunier, C., De Pauw, E., Amicosante, G., Frère, J.-M., & Galleni, M. (1999). Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-beta-lactamase IMP-1 produced by Escherichia coli. Antimicrobial Agents and Chemotherapy, 43 (4), 902-6. doi:10.1128/aac.43.4.902
Peer Reviewed verified by ORBi

Paul-Soto, R., Bauer, R., Frère, J.-M., Galleni, M., Meyer-Klaucke, W., Nolting, H., Rossolini, G. M., DE SENY, D., Hernandez-Valladares, M., Zeppezauer, M., & Adolph, H. W. (1999). Mono- and binuclear Zn2+-beta-lactamase. Role of the conserved cysteine in the catalytic mechanism. Journal of Biological Chemistry, 274 (19), 13242-9. doi:10.1074/jbc.274.19.13242
Peer Reviewed verified by ORBi

Damblon, C., Prosperi, C., Lian, L. Y., Barsukov, I., Soto, R. P., Galleni, M., Frère, J.-M., & Roberts, G. C. K. (1999). H-1-N-15 HMQC for the identification of metal-bound histidines in Cd-113-substituted Bacillus cereus zinc beta-lactamase. Journal of the American Chemical Society, 121 (49), 11575-11576. doi:10.1021/ja992896h
Peer Reviewed verified by ORBi

Rossolini, G. M., Franceschini, N., Lauretti, L., Caravelli, B., Riccio, M. L., Galleni, M., Frère, J.-M., & Amicosante, G. (1999). Cloning of a Chryseobacterium (Flavobacterium) meningosepticum chromosomal gene (blaA(CME)) encoding an extended-spectrum class A beta-lactamase related to the Bacteroides cephalosporinases and the VEB-1 and PER beta-lactamases. Antimicrobial Agents and Chemotherapy, 43 (9), 2193-9. doi:10.1128/aac.43.9.2193
Peer Reviewed verified by ORBi

Paul-Soto, R., Zeppezauer, M., Adolph, H. W., Galleni, M., Frère, J.-M., Carfi, A., Dideberg, O., Wouters, J., Hemmingsen, L., & Bauer, R. (1999). Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study. Biochemistry, 38 (50), 16500-6. doi:10.1021/bi9911381
Peer Reviewed verified by ORBi

Carfi, A., Duee, E., Paul-Soto, R., Galleni, M., Frère, J.-M., & Dideberg, O. (1998). X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form. Acta Crystallographica. Section D, Biological Crystallography, 54 (Pt 1), 45-57. doi:10.1107/s090744499700927x
Peer Reviewed verified by ORBi

Charlier, P., Coyette, J., Dehareng, D., Dive, G., Duez, C., Dusart, J., Fonzé, E., Fraipont, C., Frère, J.-M., Galleni, M., Goffin, C., Joris, B., Lamotte-Brasseur, J., & Nguyen-Distèche, M. (1998). Résistance bactérienne aux beta-lactamines. MS. Medecine Sciences, 14 (5), 544-555. doi:10.4267/10608/1092
Peer Reviewed verified by ORBi

Paul-Soto, R., Hernandez-Valladares, M., Galleni, M., Bauer, R., Zeppezauer, M., Frère, J.-M., & Adolph, H. W. (1998). Mono- and binuclear Zn-beta-lactamase from Bacteroides fragilis: catalytic and structural roles of the zinc ions. FEBS Letters, 438 (1-2), 137-40. doi:10.1016/S0014-5793(98)01289-7
Peer Reviewed verified by ORBi

Rossolini, G. M., Franceschini, N., Riccio, M. L., Mercuri, P., Perilli, M., Galleni, M., Frère, J.-M., & Amicosante, G. (1998). Characterization and sequence of the Chryseobacterium (Flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile. Biochemical Journal, 332 ( Pt 1), 145-52. doi:10.1042/bj3320145
Peer Reviewed verified by ORBi

Bounaga, S., Laws, A. P., Galleni, M., & Page, M. I. (1998). The mechanism of catalysis and the inhibition of the Bacillus cereus zinc-dependent beta-lactamase. Biochemical Journal, 331 ( Pt 3), 703-11. doi:10.1042/bj3310703
Peer Reviewed verified by ORBi

Hernandez Valladares, M., Felici, A., Weber, G., Adolph, H. W., Zeppezauer, M., Rossolini, G. M., Amicosante, G., Frère, J.-M., & Galleni, M. (23 September 1997). Zn(Ii) Dependence of the Aeromonas Hydrophila Ae036 Metallo-Beta-Lactamase Activity and Stability. Biochemistry, 36 (38), 11534-41. doi:10.1021/bi971056h
Peer Reviewed verified by ORBi

Quinting, B., Reyrat, J. M., Monnaie, D., Amicosante, G., Pelicic, V., Gicquel, B., Frère, J.-M., & Galleni, M. (14 April 1997). Contribution of Beta-Lactamase Production to the Resistance of Mycobacteria to Beta-Lactam Antibiotics. FEBS Letters, 406 (3), 275-8. doi:10.1016/S0014-5793(97)00286-X
Peer Reviewed verified by ORBi

Quinting, B., Galleni, M., Timm, J., Gicquel, B., Amicosante, G., & Frère, J.-M. (01 April 1997). Purification and Properties of the Mycobacterium Smegmatis Mc(2)155 Beta-Lactamase. FEMS Microbiology Letters, 149 (1), 11-5. doi:10.1016/S0378-1097(97)00041-4
Peer Reviewed verified by ORBi

Felici, A., Perilli, M., Franceschini, N., Rossolini, G. M., Galleni, M., Frère, J.-M., Oratore, A., & Amicosante, G. (1997). Sensitivity of Aeromonas hydrophila carbapenemase to delta3-cephems: comparative study with other metallo-beta-lactamases. Antimicrobial Agents and Chemotherapy, 41 (4), 866-8. doi:10.1128/aac.41.4.866
Peer Reviewed verified by ORBi

Perez-Llarena, F., Martin, J. F., Galleni, M., Coque, J. J., Fuente, J. L., Frère, J.-M., & Liras, P. (1997). The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity. Journal of Bacteriology, 179 (19), 6035-40. doi:10.1128/jb.179.19.6035-6040.1997
Peer Reviewed verified by ORBi

Hernandez Villadares, M., Galleni, M., Frère, J.-M., Felici, A., Perilli, M., Franceschini, N., Rossolini, G. M., Oratore, A., & Amicosante, G. (1996). Overproduction and purification of the Aeromonas hydrophila CphA metallo-beta-lactamase expressed in Escherichia coli. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 2 (2), 253-6. doi:10.1089/mdr.1996.2.253
Peer Reviewed verified by ORBi

Evrard, B., MELIN, P., Galleni, M., ART, M.-C., & De Mol, P. (October 1995). Etude des beta-lactamases de 7 souches hospitalières de Klebsiella pneumoniae [Poster presentation]. Symposium National de la Société Belge de Biologie Clinique, Belgium.

Galleni, M., Lamotte-Brasseur, J., Raquet, X., Dubus, A., Monnaie, D., Knox, J. R., & Frère, J.-M. (11 May 1995). The Enigmatic Catalytic Mechanism of Active-Site Serine Beta-Lactamases. Biochemical Pharmacology, 49 (9), 1171-8. doi:10.1016/0006-2952(94)00502-D
Peer Reviewed verified by ORBi

Lepage, S., Lakaye, B., Galleni, M., Thamm, I., Crine, M., Groslambert, S., & Frère, J.-M. (April 1995). Saturation of Penicillin-Binding Protein 1 by Beta-Lactam Antibiotics in Growing Cells of Bacillus Licheniformis. Molecular Microbiology, 16 (2), 365-72. doi:10.1111/j.1365-2958.1995.tb02308.x
Peer Reviewed verified by ORBi

Galleni, M., Raquet, X., Lamotte-Brasseur, J., Fonze, E., Amicosante, G., & Frère, J.-M. (February 1995). Dd-Peptidases and Beta-Lactamases: Catalytic Mechanisms and Specificities. Journal of Chemotherapy, 7 (1), 3-7. doi:10.1179/joc.1995.7.1.3
Peer Reviewed verified by ORBi

Felici, A., Perilli, M., Segatore, B., Franceschini, N., Setacci, D., Oratore, A., Stefani, S., Galleni, M., & Amicosante, G. (1995). Interactions of biapenem with active-site serine and metallo-beta-lactamases. Antimicrobial Agents and Chemotherapy, 39 (6), 1300-5. doi:10.1128/AAC.39.6.1300
Peer Reviewed verified by ORBi

Matagne, A., Ledent, P., Monnaie, D., Felici, A., Jamin, M., Raquet, X., Galleni, M., Klein, D., Francois, I., & Frère, J.-M. (January 1995). Kinetic Study of Interaction between Brl 42715, Beta-Lactamases, and D-Alanyl-D-Alanine Peptidases. Antimicrobial Agents and Chemotherapy, 39 (1), 227-31. doi:10.1128/aac.39.1.227
Peer Reviewed verified by ORBi

Carfi, A., Pares, S., Duée, E., Galleni, M., Duez, C., Frère, J.-M., & Dideberg, O. (1995). The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO Journal, 14 (20), 4914-4921. doi:10.1002/j.1460-2075.1995.tb00174.x
Peer Reviewed verified by ORBi

Lepage, S., Galleni, M., Lakaye, B., Joris, B., Thamm, I., & Frère, J.-M. (1995). Kinetic properties of the Bacillus licheniformis Penicillin-binding proteins. Biochemical Journal, 309, 49-53. doi:10.1042/bj3090049
Peer Reviewed verified by ORBi

Galleni, M., Franceschini, N., Quinting, B., Fattorini, L., Orefici, G., Oratore, A., Frère, J.-M., & Amicosante, G. (July 1994). Use of the Chromosomal Class a Beta-Lactamase of Mycobacterium Fortuitum D316 to Study Potentially Poor Substrates and Inhibitory Beta-Lactam Compounds. Antimicrobial Agents and Chemotherapy, 38 (7), 1608-14. doi:10.1128/AAC.38.7.1608
Peer Reviewed verified by ORBi

Lakaye, B., Damblon, C., Jamin, M., Galleni, M., Lepage, S., Joris, B., Marchand-Brynaert, J., Frydrychh, C., & Frère, J.-M. (1994). Synthesis, purification and kinetic properties of fluorescein-labelled penicillins. Biochemical Journal, 300, 141-145. doi:10.1042/bj3000141
Peer Reviewed verified by ORBi

Datz, M., Joris, B., Azab, E. A., Galleni, M., Van Beeumen, J., Frère, J.-M., & Martin, H. H. (1994). A common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase. European Journal of Biochemistry, 226 (1), 149-57. doi:10.1111/j.1432-1033.1994.tb20036.x
Peer Reviewed verified by ORBi

Joris, B., Galleni, M., Frère, J.-M., & Labia, R. (1994). Analysis of the penA gene of Pseudomonas cepacia 249. Antimicrobial Agents and Chemotherapy, 38 (2), 407-8. doi:10.1128/AAC.38.2.407
Peer Reviewed verified by ORBi

Granier, B., Jamin, M., Adam, M., Galleni, M., Lakaye, B., Zorzi, W., Grandchamps, J., Wilkin, J.-M., Fraipont, C., Joris, B., Duez, C., Nguyen-Distèche, M., Coyette, J., Leyh-Bouille, M., Dusart, J., Christians, L., Frère, J.-M., & Ghuysen, J.-M. (1994). Serine-Type D-Ala-D-Ala Peptidases and Penicillin-Binding Proteins. Methods in Enzymology, 244, 249-266. doi:10.1016/0076-6879(94)44021-2
Peer Reviewed verified by ORBi

Galleni, M., Lakaye, B., Lepage, S., Jamin, M., Thamm, I., Joris, B., & Frère, J.-M. (01 April 1993). A New, Highly Sensitive Method for the Detection and Quantification of Penicillin-Binding Proteins. Biochemical Journal, 291 ((Pt 1)), 19-21. doi:10.1042/bj2910019
Peer Reviewed verified by ORBi

Franceschini, N., Galleni, M., Frère, J.-M., Oratore, A., & Amicosante, G. (1993). A class-A beta-lactamase from Pseudomonas stutzeri that is highly active against monobactams and cefotaxime. Biochemical Journal, 292 ( Pt 3), 697-700. doi:10.1042/bj2920697
Peer Reviewed verified by ORBi

Adam, M., Damblon, C., Jamin, M., Zorzi, W., Dusart, V., Galleni, M., El Kharroubi, A., Piras, G., Spratt, B. G., Keck, W., Coyette, J., Ghuysen, J.-M., NGuyen-Distèche, M., & Frère, J.-M. (1991). Acyltransferase activities of the high-molecular-mass essential penicillin-binding proteins. Biochemical Journal, 279 (Part 2), 601-604. doi:10.1042/bj2790601
Peer Reviewed verified by ORBi

Frère, J.-M., Joris, B., Jacob, F., Matagne, A., Monnaie, D., Jamin, M., Hadonou, M., Bourguignon-Bellefroid, C., Varetto, L., Wilkin, J.-M., Dubus, A., Damblon, C., Adam, M., Ledent, P., De Meester, F., & Galleni, M. (1991). Mechanism of action of β-lactamases and DD-peptidases. In U. K. Pandit & F. C. Alderweireldt (Eds.), Bioorganic Chemistry in Healthcare and Technology (pp. 161-170). New York, United States - New York: Plenum Press.
Peer reviewed

Galleni, M., Amicosante, G., & Frère, J.-M. (01 October 1988). A Survey of the Kinetic Parameters of Class C Beta-Lactamases. Cephalosporins and Other Beta-Lactam Compounds. Biochemical Journal, 255 (1), 123-9. doi:10.1042/bj2550123
Peer Reviewed verified by ORBi

Galleni, M., & Frère, J.-M. (01 October 1988). A Survey of the Kinetic Parameters of Class C Beta-Lactamases. Penicillins. Biochemical Journal, 255 (1), 119-22. doi:10.1042/bj2550119
Peer Reviewed verified by ORBi

Galleni, M., Lindberg, F., Normark, S., Cole, S., Honore, N., Joris, B., & Frère, J.-M. (15 March 1988). Sequence and Comparative Analysis of Three Enterobacter Cloacae Ampc Beta-Lactamase Genes and Their Products. Biochemical Journal, 250 (3), 753-60. doi:10.1042/bj2500753
Peer Reviewed verified by ORBi

Amicosante, G., Oratore, A., Franceschini, N., Maccarrone, M., Strom, R., Galleni, M., & Frère, J.-M. (1988). Citrobacter diversus ULA-27 beta-lactamases. Improved purification and general properties. Biochemical Journal, 254 (3), 885-90. doi:10.1042/bj2540885
Peer Reviewed verified by ORBi

Amicosante, G., Oratore, A., Joris, B., Galleni, M., Frère, J.-M., & Van Beeumen, J. (1988). Chromosome-encoded beta-lactamases of Citrobacter diversus. Interaction with beta-iodopenicillanate and labelling of the active site. Biochemical Journal, 254 (3), 891-3. doi:10.1042/bj2540891
Peer Reviewed verified by ORBi

Joris, B., De Meester, F., Galleni, M., Frère, J.-M., & Van Beeumen, J. (1987). The K1 beta-lactamase of Klebsiella pneumoniae. Biochemical Journal, 243 (2), 561-7. doi:10.1042/bj2430561
Peer Reviewed verified by ORBi

Joris, B., De Meester, F., Galleni, M., Masson, S., Dusart, J., Frère, J.-M., Van Beeumen, J., Bush, K., & Sykes, R. (1986). Properties of a class C beta-lactamase from Serratia marcescens. Biochemical Journal, 239 (3), 581-6. doi:10.1042/bj2390581
Peer Reviewed verified by ORBi

Joris, B., De Meester, F., Galleni, M., Reckinger, G., Coyette, J., Frère, J.-M., & Van Beeumen, J. (1985). The beta-lactamase of Enterobacter cloacae P99. Chemical properties, N-terminal sequence and interaction with 6 beta-halogenopenicillanates. Biochemical Journal, 228 (1), 241-8. doi:10.1042/bj2280241
Peer Reviewed verified by ORBi

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