Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39

Frère, Jean-Marie; Ghuysen, Jean-Marie; Degelaen, Jacques; Loffet, Albert; Perkins, Harold R.

doi:10.1038/258168a0

Article (Scientific journals)

Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39

Frère, Jean-Marie; Ghuysen, Jean-Marie; Degelaen, Jacques et al.

1975 • In Nature, 258 (5531), p. 168-170

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/85186

DOI
10.1038/258168a0

PubMed
1186898

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Keywords :

carboxypeptidases/*metabolism; muramoylpentapeptide carboxypeptidase/*metabolism; penicillin g/*metabolism; streptomyces/*enzymology; structure-activity relationship

Disciplines :

Microbiology
Biochemistry, biophysics & molecular biology

Author, co-author :

Frère, Jean-Marie ; Université de Liège - ULiège > Faculté de Médecine, Institut de Botanique > Service de Microbiologie

Ghuysen, Jean-Marie ; Université de Liège - ULiège > Faculté de Médecine, Institut de Botanique > Service de Microbiologie

Degelaen, Jacques; Université Catholique de Louvain - UCL > Laboratoire de Chimie Physique et de Cristallographie

Loffet, Albert; UCB > Division Pharmaceutique

Perkins, Harold R.; University of Liverpool > Department of Microbiology

Language :

English

Title :

Fragmentation of benzylpenicillin after interaction with the exocellular DD-carboxypeptidase-transpeptidases of Streptomyces R61 and R39

Publication date :

13 November 1975

Journal title :

Nature

ISSN :

0028-0836

eISSN :

1476-4687

Publisher :

Nature Publishing Group, Basingstoke, United Kingdom

Volume :

258

Issue :

5531

Pages :

168-170

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

FRFC - Fonds de la Recherche Fondamentale Collective

Available on ORBi :

since 17 February 2011

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Bibliography

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Frère, J. M., et al, Biochem. J., 143, 233-240 (1974).
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Schmid, R., and Plapp, R., Arch. Mikrobiol., 83, 246-260 (1972).
Blumberg, P. M., Yocum R. R., Willoughby, E., and Strominger, J. L., J. moiec. Biol., 249, 6828-6835 (1974).