![]() | Ghuysen, J.-M. (1957). Activités bactériolytiques de l’actinomycétine de streptomyces albus G. Unpublished post doctoral thesis (Agrégation de l'enseignement supérieur), ULiège - Université de Liège. Jury: . |
![]() | Ghuysen, J.-M. (1951). Etude de l’hétérogénéité de l’acide ribonucléique de la levure. Unpublished doctoral thesis, ULiège - Université de Liège. Jury: . |
Ghuysen, J.-M., & Hackenbeck, R. (1994). Bacterial cell wall. Amesterdam, Netherlands: Elsevier. |
Ghuysen, J.-M. (1977). E. R. Squibb Lectures on Chemistry of Microbial Products. The Bacterial DD-carboxypeptidase Enzyme System: A New Insight into the Mode of Action of Penicillin. Tokyo, Japan: University of Tokyo Press. |
Ghuysen, J.-M. (1977). The bacterial DD-carboxypeptidase-transpeptidase enzyme system : a new insight into the mode of action of penicillin. Tokyo, Japan: University of Tokyo Press. |
Ghuysen, J.-M. (2004). Zinc D-Ala-D-Ala carboxypeptidase (Streptomyces). In A. J. Barret, N. D. Rawling, ... J. F. Woessner (Eds.), Handbook of Proteolytic Enzymes. vol 2 Cysteine, Serine and Threonine Peptidases (2ème éd, pp. 857-858). Academic Press. |
Ghuysen, J.-M. (2004). Streptomyces K15 D-Ala-D-Ala transpeptidase. In A. J. Barret, N. D. Rawling, ... J. F. Woessner (Eds.), Handbook of Proteolytic Enzymes. vol 2 Cysteine, Serine and Threonine Peptidases (2ème éd, pp. 1956-1959). Academic Press. |
![]() | Ghuysen, J.-M., & Frère, J.-M. (2004). B-Lactam Antibiotics. In Encyclopedic Reference of Molecular Pharmacology (pp. 679-683). Springer. |
![]() | Ghuysen, J.-M. (1998). Zinc D-Ala-D-Ala carboxypeptidase. In A. J. Barrett, N. D. Rawlings, ... J. F. Woessner, Handbook of Proteolytic Enzymes (pp. 1354-1356). Academic Press. |
![]() | Ghuysen, J.-M., & Dive, G. (1994). Biochemistry of the penicilloyl serine transferases. In J.-M. Ghuysen & R. Hackenbeck (Eds.), Bacterial cell wall (pp. 103-129). Amesterdam, Netherlands: Elsevier. doi:10.1016/S0167-7306(08)60409-3 |
Joris, B., Hardt, K., & Ghuysen, J.-M. (1994). Induction of β-lactamase and low-affinity penicillin binding protein 2' synthesis in gram-positive bacteria. In J.-M. Ghuysen & R. Hakenbeck (Eds.), Bacterial Cell Wall. vol 27 (pp. 505-515). Elsevier. doi:10.1016/S0167-7306(08)60427-5 ![]() |
![]() | Englebert, S., El Kharroubi, A., Piras, G., Joris, B., Coyette, J., Nguyen-Distèche, M., & Ghuysen, J.-M. (1993). Modular Design of the Bi(multi?) functional penicillin-binding proteins. In De pedro, J. V. Höltje, ... W. Loffelhardt (Eds.), Bacterial Growth & Lysis Metabolism and Structure of the Bacterial Sacculus (pp. 319-333). New York, United States: Plenum Press. ![]() |
![]() | El Kharroubi, A., Jacques, P., Piras, G., Coyette, J., & Ghuysen, J.-M. (1988). Characterization of the Trypsin-Solubilized Penicillin-Binding Proteins of Enterococcus hirae (Streptococcus faecium). In P. Actor, L. Daneo-Moore, M. L. Higgins, M. R. J. Salton, ... G. D. Schokman (Eds.), Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function (pp. 367-376). Washington, United States - District of Columbia: American Society for Microbiology. |
![]() | Jacques, P., El Kharroubi, A., Joris, B., Dussenne, B., Thonon, F., Piras, G., Coyette, J., & Ghuysen, J.-M. (1988). Purification and Characterization of a β-lactam-Resistant Penicillin-Binding Protein from Enterococcus hirae (Streptococcus faecium). In P. Actor, L. Daneo-Moore, M. L. Higgins, M. R. J. Salton, ... G. D. Shockman (Eds.), Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function (pp. 377-381). Washington, United States - District of Columbia: American Society for Microbiology. |
Ghuysen, J.-M. (1987). The D-alanyl-D-alanine-cleaving peptidases and β-lactamases. Structure and mechanism. In J. M. Cardoso Duarte, L. J. Archer, A. T. Bull, ... G. Holt (Eds.), Perspectives in Biotechnology (pp. 67-95). Springer. doi:10.1007/978-1-4613-1883-5_6 ![]() |
![]() | Ghuysen, J.-M., Nguyen-Distèche, M., & Rousset, A. (1986). β-Lactam-induced Proteus L-forms. In S. Madoff (Ed.), The Bacterial L-Forms, vol. 17 (Department of Medecine and Bacteriology, Massachusetts General Hospital, pp. 127-162). New-York, United States - New York: Marcel Dekker, Inc. |
![]() | Ghuysen, J.-M. (1984). Exploration of active sites of DD-peptidases. In W. Paton (Ed.), J. Mitchel (Ed.), P. Turner (Ed.), C. Padgham (Other coll.), ... E. Aschcroft (Other coll.), Iuphar 9th International Congress of Pharmacology, London 1984. Proceedings. Scientific & Medical Division, Macmillan Press. |
![]() | Coyette, J., Somzé, A., Briquet, J.-J., Ghuysen, J.-M., & Fontana, R. (1983). Function of Penicillin-binding protein 3 in Streptococcus Faecium. In R. Hakenbeck, J.-V. Höltje, ... H. Labischinski (Eds.), The Target Penicillin : the Murein Sacculus of Bacterial Cell Walls Architecture and Growth : Proceedings (pp. 523-529). Walter de Gruyter & Co. |
Charlier, P., Dideberg, O., Dive, G., Dusart, J., Frère, J.-M., Ghuysen, J.-M., Joris, B., Lamotte-Brasseur, J., Leyh-Bouille, M., & Nguyen-Distèche, M. (1983). The active sites of the D-alanyl-D-alanine-cleaving peptidases. In R. Hakenbeck, J.-V. Höltje, ... H. Labischinski (Eds.), The Target Penicillin : the Murein Sacculus of Bacterial Cell Walls Architecture and Growth : Proceedings (pp. 369-386). Berlin, Germany: Walter de Gruyter & Co. ![]() |
![]() | Charlier, P., Dideberg, O., Dive, G., Dusart, J., Frère, J.-M., Ghuysen, J.-M., Joris, B., Lamotte-Brasseur, J., Leyh-Bouille, M., & Nguyen-Distèche, M. (1983). The active site of the D-alanyl-D-Alanine-cleaving peptidase. In R. Hakenbeck, J. V. Höltje, ... H. Labischinski (Eds.), Target of Penicillin: The Murein Sacculus of Bacterial Cell Walls, Architecture and Growth (pp. 369-386). De Gruyter. |
![]() | Ghuysen, J.-M., Charlier, P., Coyette, J., Dideberg, O., Dive, G., Dusart, J., Frère, J.-M., Joris, B., Lamotte-Brasseur, J., Leyh-Bouille, M., & Nguyen-Distèche, M. (1983). Instrinct Resistance to beta-lactam antibiotics at the level of the enzyme sites. Many challenges, some achievements. In B. Wiedemann, J.-M. Guysen, K. H. Spitzy, K. Karrer, S. Brayer, R. Lenzhofer, K. Moser, H. Pichler, ... H. Rainer (Eds.), Symposium Mechanisms of resistance to beta-lactam antibiotics : Proceedings. ![]() |
Ghuysen, J.-M., Frère, J.-M., Ley-Bouille, M., & Dideberg, O. (1981). The d-alanyl-d-Ala peptidases. Mechanism of action of penicillins and delta-3-cephalosporins. In M. Salton & G. D. Shockman (Eds.), Beta-Lactam Antibiotics: Mode of Action, New Development, and Future Prospects (pp. 127-152). New York, United States - New York: Academic Press. |
![]() | Ghuysen, J.-M., Frère, J.-M., Leyh-Bouille, M., Dideberg, O., Lamotte-Brasseur, J., Perkins, H. R., & De Coen, J.-L. (1981). Penicillins and Δ3-cephalosporins as inhibitors and mechanism-based inactivators of D-alanyl-D-Ala peptidases. In A. S. V. Burgen & G. C. K. Roberts (Eds.), Topics in molecular pharmacology (pp. 64-96). Elsevier. ![]() |
![]() | Ghuysen, J.-M., Frère, J.-M., Leyh-Bouille, M., Coyette, J., Duez, C., Joris, B., Dusart, J., Nguyen-Distèche, M., DideberG, O., Charlier, P., Knox, J. R., Kelly, J. A., Moews, P. C., & DeLucia, M. L. (1981). Mechanistic properties and functioning of DD-carboxypeptidase. In S. Mitsuhashi (Ed.), β-Lactam Antbiotics (pp. 185-202). Tokyo, Japan: Japan Scientific Society Press, Springer. |
Ghuysen, J.-M., Frère, J.-M., Leyh-Bouille, M., & Dideberg, O. (1981). Mode of action of penicillins and Δ3-cephalosporins. On the active centers of serine and zinc(2+) D-alanyl-D-Ala peptidases. In R. N. Ondarza & T. P. Singer (Eds.), Molecular basis of drug action: proceedings of the International Symposium on Molecular Basis of Drug Action, held in Querétaro, Mexico, October 13-16, 1980 (pp. 3-30). Elsevier. ![]() |
![]() | Charlier, P., Coyette, J., Dideberg, O., Duez, C., Dusart, J., Frère, J.-M., Ghuysen, J.-M., Joris, B., Leyh-Bouille, M., & Nguyen-Distèche, M. (1980). On the Active Centers of Serine and Zn II DD-carboxyppetidases. In G. I. Gregory (Ed.), Recent advances in the Chemistry of beta-lactam antibiotics (pp. 184-202). London, United Kingdom: The Royal Society of Chemistry. |
Ghuysen, J.-M. (1980). Antibiotics and peptidoglycan metabolism. In P. G. Sammes (Ed.), Topics in Antibiotic Chemistry. vol 5 (pp. 9-117). Ellis Horwood Ltd. |
![]() | Frère, J.-M., Duez, C., Dusart, J., Coyette, J., Leyh-Bouille, M., Ghuysen, J.-M., Dideberg, O., & Knox, J. (1980). Mode of action of B-lactam antibiotics at the molecular level. In M. Sandler, Enzyme inhibitors as drugs (pp. 183-207). Macmillan. ![]() |
![]() | Ghuysen, J.-M. (1979). Interaction between B-lactam antibiotics and the enzymes of the wall peptidoglycan crosslinking system. In J. M. T. Hamilton-Miller, Beta-lactamases (pp. 181-204). Londres, United Kingdom: Academic press. |
![]() | Marquet, A., Nguyen-Distèche, M., Leyh-Bouille, M., & Ghuysen, J.-M. (1978). Purification of DD-carboxypeptidases from Streptomyces strains R61 and K15 by antigen-antibody affinity chromatography. In O. Hoffmann-Ostenhof (Ed.), Affinity chromatography : biospecific sorption, the first extensive compendium on affinity chromatography as applied to biochemistry and immunochemistry (pp. 251-255). Elsevier. ![]() |
![]() | Ghuysen, J.-M. (1977). Biosynthesis and assembly of bacterial cell walls. In G. Poste & G. L. Nicolson (Eds.), The synthesis, assembly and turnover of celle surface components (pp. 463-595). Elsevier. |
![]() | Frère, J.-M., Leyh-Bouille, M., Ghuysen, J.-M., Nieto, M., & Perkins, H. R. (1976). [51] Exocellular dd-carboxypeptidases-transpeptidases from Streptomyces. In L. Lorand (Ed.), Part B: Proteolytic Enzymes (pp. 610-636). Academic Press. doi:10.1016/S0076-6879(76)45054-1 ![]() |
![]() | Frère, J.-M., Leyh-Bouille, M., Dusart, J., Coyette, J., & Ghuysen, J.-M. (1976). Penicillin-transpeptidase interaction. In A. Loffett, J. Christophe, ... M. Svoboda, Peptides 1976: proceedings of the Fourteenth European Peptide Symposium, Wepion, Belgium, April 11-17, 1976 (pp. 385-399). Bruxelles, Belgium: Editions Universelles. ![]() |
![]() | Ghuysen, J.-M. (1975). La paroi bactérienne. In F. Gasser (Ed.), Bactéries, bactériophages : cours de l'Institut Pasteur (pp. 125-148). Ediscience-MacGraw-Hill. |
![]() | Ghuysen, J.-M., Perkins, H., Frère, J.-M., & Nieto, M. (1974). Antibiotic action on enzymes involved in peptidoglycan synthesis. In H. Sund, Protein-ligand interactions : proceedings of a symposium held at the University of Konstanz (pp. 372-384). Konstanz, Germany: De Gruyter. ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Frère, J.-M., Dusart, J., Marquet, A., Perkins, H. R., & Nieto, M. (1974). The penicillin Target in Bacteria. In B. Spencer (Ed.), Industrial Aspects of Biochemistry (FEBS Proceedings) (pp. 579-605). Elsevier. doi:10.1002/food.19750190412 ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Perkins, H.-R., & Nieto, M. (1973). Bacterial Peptidoglycans in Relation to the Membrane and the Mechanism of Action of Penicillin. In Z. Vanek, Z. Hostalek, ... J. Cudlin (Eds.), Genetics of industrial microorganisms. Bacteria (pp. 297-316). Prague, Czechia: Academia. |
![]() | Dusart, J., Marquet, A., & Ghuysen, J.-M. (1973). Exocellular and membrane-bound transpeptidases in Streptomyces. In 1st International Congress for Bacteriology, Jerusalem, 2-7 September, 1973. Abstracts. Vol. II. Free papers (pp. 176-177). |
![]() | Ghuysen, J.-M. (1973). Biosynthesis of Peptidoglycan. In L. Dekker (Ed.), The Bacterial Membranes and Walls (pp. 37-130). New-York, United States: Dekker. |
![]() | Perkins, H. R., Ghuysen, J.-M., Nieto, M., Leyh-Bouille, M., & Frère, J.-M. (1973). DD-carboxypeptidases/Transpeptidases and Penicillin Action. In 1st International Congress for Bacteriology, Jerusalem, 2-7 September, 1973. Abstracts. Vol I. Symposia. |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Frère, J.-M., Dusart, J., Perkins, H. R., & Nieto, M. (1972). The Streptomyces DD-carboxypeptidase-transpeptidase system as a model for the study of penicillin action. In P. Pratesi (Ed.), Medicinal Chemistry : Special contributions - Milan 1972 (pp. 1-11). London, United Kingdom: Butterworths. |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Frère, J.-M., Dusart, J., Johnson, K., Nakel, M., Coyette, J., Perkins, H., & Nieto, M. (1972). Streptomyces DD carboxypeptidases-transpeptidases and mechanism of action of penicillin. In E. Munoz, Molecular mechanisms of antibiotic action on protein biosynthesis and membranes (pp. 406-426). Elsevier. ![]() |
![]() | Ghuysen, J.-M. (1971). Bacterial walls and membranes. In Z. M. Bacq, Functions of Subcellular Structures (pp. 143-152). Oxford, United States - New York: Pergamon Press. |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Nakel, M., Dusart, J., Johnson, K., & Frère, J.-M. (1971). DD-carboxypeptidases and Mechanism of Action of Penicillin. In E. Muñoz, F. García-Ferrandiz, ... D. Vazquez (Eds.), Molecular mechanisms of antibiotic action on protein biosynthesis and membranes. Proceedings of a symposium held at the University of Granada (Spain) June 1st-4th (pp. 51-51). Elsevier. |
![]() | Leyh-Bouille, M., Ghuysen, J.-M., Bonaly, R., Nueto, M., Perkins, H. R., Schliefer, K. H., & Kandler, O. (1970). Extracellular, penicillin-resistant DD-carboxypeptidase from Streptomyces SP [abstract]. In Xe Congresso Internacional de Microbiologica - Resumenes - abstracts - résumés (pp. 33). |
![]() | Ghuysen, J.-M., & Leyh-Bouille, M. (1970). Bacterial Wall Peptidoglycans; Mecanism of Action of Penicillin. In Genetics of Industrial Microorganisms : abstact book (pp. 9-1). |
![]() | Ghuysen, J.-M. (1970). Functions of Subcellular Structures. In Z. M. Bacq (Ed.), Fundamentals of Biochemical Pharmacology (pp. 143-184). Pergamon Press. |
![]() | Guinand, M., Ghuysen, J.-M., Leyh-Bouille, M., Coyette, J., & ven Heijenoort, J. (1969). A streptomyces Carboxypeptidase Active on. In 6th FEBS Meeting Abstracts. |
![]() | Ghuysen, J.-M. (1969). Biochemistry of the wall peptidoglycan in the Procaryotic Cells in relation to the membrane. In 6th FEBS Meeting Abstracts. |
![]() | Ghuysen, J.-M., Leger, G., & Dierickx, L. (1958). Production et isolement du complexe protéolytique de streptomyces spp., Son application à l'épilage et au confitage simultanés des peaux. In XXXIème Congrès International de Chimie Industrielle (pp. 671-674). ![]() |
![]() | Welsch, M., Ghuysen, J.-M., & Castermans, A. (1956). Multiplicity of bacteriolytic agents in actinomycetin. In C. Liébecq (Ed.), Proceedings of the third international congress of biochemistry, Brussels 1955 (pp. 413-415). New York, United States - New York: Academic Press. |
![]() | Goffin, C., & Ghuysen, J.-M. (December 2002). Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: Presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent. Microbiology and Molecular Biology Reviews, 66 (4), 702-738. doi:10.1128/MMBR.66.4.702-738.2002 ![]() |
![]() | Marrec-Fairley, M., Piette, A., Gallet, X., Brasseur, R., Hara, H., Fraipont, C., Ghuysen, J.-M., & Nguyen-Disteche, M. (September 2000). Differential Functionalities of Amphiphilic Peptide Segments of the Cell-Septation Penicillin-Binding Protein 3 of Escherichia Coli. Molecular Microbiology, 37 (5), 1019-1031. doi:10.1046/j.1365-2958.2000.02054.x ![]() |
![]() | Terrak, M., Ghosh, T. K., van Heijenoort, J., Van Beeumen, J., Lampilas, M., Aszodi, J., Ayala, J. A., Ghuysen, J.-M., & Nguyen-Distèche, M. (October 1999). The Catalytic, Glycosyl Transferase and Acyl Transferase Modules of the Cell Wall Peptidoglycan-Polymerizing Penicillin-Binding Protein 1b of Escherichia Coli. Molecular Microbiology, 34 (2), 350-364. doi:10.1046/j.1365-2958.1999.01612.x ![]() |
![]() | Ghuysen, J.-M., & Goffin, C. (October 1999). Lack of Cell Wall Peptidoglycan Versus Penicillin Sensitivity: New Insights into the Chlamydial Anomaly. Antimicrobial Agents and Chemotherapy, 43 (10), 2339-2344. doi:10.1128/aac.43.10.2339 ![]() |
![]() | Ghuysen, J.-M. (03 December 1998). La résistance bactérienne aux antibiotiques, un modèle exemplaire d'évolution moléculaire dirigée. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 60 (4), 287-294. ![]() |
![]() | Goffin, C., & Ghuysen, J.-M. (December 1998). Multimodular Penicillin-Binding Proteins: An Enigmatic Family of Orthologs and Paralogs. Microbiology and Molecular Biology Reviews, 62 (4), 1079-1093. doi:10.1128/mmbr.62.4.1079-1093.1998 ![]() |
![]() | Raze, D., Dardenne, O., Hallut, S., Martinez-Bueno, M., Coyette, J., & Ghuysen, J.-M. (March 1998). The Gene Encoding the Low-Affinity Penicillin-Binding Protein 3r in Enterococcus Hirae S185r Is Borne on a Plasmid Carrying Other Antibiotic Resistance Determinants. Antimicrobial Agents and Chemotherapy, 42 (3), 534-539. doi:10.1128/aac.42.3.534 ![]() |
![]() | Ghuysen, J.-M. (1998). La paroi bactérienne et la résistance à la pénicilline: faits, questions et espoirs. Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique, 153 (4), 235-41. ![]() |
![]() | Ghuysen, J.-M. (1998). La résistance bactérienne aux antibiotiques, un modèle exemplaire d'évolution moléculaire dirigée. Revue Médicale de Liège, 53 (9), 529-531. ![]() |
![]() | Zhao, G., Duez, C., Forceille, C., Rhazi, N., Klein, D., Ghuysen, J.-M., Frère, J.-M., & Lepage, S. (15 October 1997). Site-Directed Mutagenesis of the Actinomadura R39 DD-Peptidase. Biochemical Journal, 327 (2), 377-381. doi:10.1042/bj3270377 ![]() |
![]() | Adam, M., Fraipont, C., Rhazi, N., Nguyen-Disteche, M., Lakaye, B., Frère, J.-M., Devreese, B., Van Beeumen, J., van Heijenoort, Y., van Heijenoort, J., & Ghuysen, J.-M. (October 1997). The Bimodular G57-V577 Polypeptide Chain of the Class B Penicillin-Binding Protein 3 of Escherichia Coli Catalyzes Peptide Bond Formation from Thiolesters and Does Not Catalyze Glycan Chain Polymerization from the Lipid II Intermediate. Journal of Bacteriology, 179 (19), 6005-6009. doi:10.1128/jb.179.19.6005-6009.1997 ![]() |
![]() | Lepage, S., Dubois, P., Ghosh, T.-K., Joris, B., Mahapatra, S., Kundu, M., Basu, J., Chakrabarti, P., Cole, S.-T., Nguyen-Distèche, M., & Ghuysen, J.-M. (July 1997). Dual Multimodular Class a Penicillin-Binding Proteins in Mycobacterium Leprae. Journal of Bacteriology, 179 (14), 4627-4630. doi:10.1128/jb.179.14.4627-4630.1997 ![]() |
![]() | Hardt, K., Joris, B., Lepage, S., Brasseur, R., Lampen, J. O., Frère, J.-M., Fink, A. L., & Ghuysen, J.-M. (1997). The Penicillin sensory transducer, blar, involved in the inducibility of beta-lactamase synthesis in bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle. Molecular Microbiology, 23 (5), 935-944. doi:10.1046/j.1365-2958.1997.2761642.x ![]() |
![]() | Ghuysen, J.-M., Charlier, P., Coyette, J., Duez, C., Fonzé, E., Fraipont, C., Goffin, C., Joris, B., & Nguyen-Distèche, M. (1997). Penicillin-binding proteins. Wall peptidoglycan assembly and resistance to penicillin: facts, doubts and hopes. International Journal of Antimicrobial Agents, 8 (1), 45-60. doi:10.1016/S0924-8579(96)00358-5 ![]() |
![]() | Goffin, C., Fraipont, C., Ayala, J., Terrak, M., Nguyen-Distèche, M., & Ghuysen, J.-M. (September 1996). The non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia Coli is required for folding and/or stability of the penicillin-binding module and the membrane-anchoring module confers cell septation activity on the folded structure. Journal of Bacteriology, 178 (18), 5402-5409. doi:10.1128/jb.178.18.5402-5409.1996 ![]() |
![]() | Mollerach, M. E., Partoune, P., Coyette, J., & Ghuysen, J.-M. (March 1996). Importance of the E-46-D-160 Polypeptide Segment of the Non-Penicillin-Binding Module for the Folding of the Low-Affinity, Multimodular Class B Penicillin-Binding Protein 5 of Enterococcus Hirae. Journal of Bacteriology, 178 (6), 1774-1775. doi:10.1128/jb.178.6.1774-1775.1996 ![]() |
![]() | Basu, J., Mahapatra, S., Kundu, M., Mukhopadhyay, S., Nguyen-Distèche, M., Dubois, P., Joris, B., Van Beeumen, J., Cole, S.-T., Chakrabarti, P., & Ghuysen, J.-M. (March 1996). Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein, PBP1. Journal of Bacteriology, 178 (6), 1707-1711. doi:10.1128/jb.178.6.1707-1711.1996 ![]() |
![]() | Chavagnat, F., Duez, C., Guinand, M., Potin, P., Barbeyron, T., Henrissat, B., Wallach, J., & Ghuysen, J.-M. (1996). Cloning, sequencing and overexpression in Escherichia coli of the alginate lyase-encoding aly gene of Pseudomonas alginovora: identification of three classes of alginate lyases. Biochemical Journal, 319 (Pt 2), 575-583. doi:10.1042/bj3190575 ![]() |
![]() | Ghuysen, J.-M., Knill, C., Kennedy, J., & Hakenbeck, R. (1996). Bacterial cell wall. Carbohydrate Polymers, 29 (3), 294. ![]() |
![]() | Ghuysen, J.-M., Charlier, P., Coyette, J., Duez, C., Fonze, E., Fraipont, C., Joris, B., Nguyen-Distèche, M., & Goffin, C. (1996). Penicillin and Beyond: Evolution, Protein Fold, Multimodular Polypeptides, and Multiprotein Complexes. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 2 (2, Summer), 163-175. doi:10.1089/mdr.1996.2.163 ![]() |
![]() | Malissard, M., Chavagnat, F., Duez, C., Vacheron, M.-J., Guinand, M., Michel, G., & Ghuysen, J.-M. (15 February 1995). Overproduction and properties of the mannuronate alginate lyase AlxMB. FEMS Microbiology Letters, 126 (2), 105-111. doi:10.1016/0378-1097(94)00536-Z ![]() |
![]() | Grandchamps, J., Nguyen-Distèche, M., Damblon, C., Frère, J.-M., & Ghuysen, J.-M. (1995). Streptomyces K15 active-site serine DD-transpeptidase: specificity profile for peptide, thiol ester and ester carbonyl donors and pathways of the transfer reactions. Biochemical Journal, 307 (Pt 2), 335-339. doi:10.1042/bj3070335 ![]() |
Delfosse, P., Ongena, M., Jacques, P., Ghuysen, J.-M., & Thonart, P. (1995). Pyoverdine-mediated uptake of iron in Pseudomonas putida BTP1 : involvement of a 100 KD IROMP. Archives Internationales de Physiologie et de Biochimie, 103 (B39). |
![]() | Ghuysen, J.-M. (October 1994). Molecular Structures of Penicillin-Binding Proteins and Beta-Lactamases. Trends in Microbiology, 2 (10), 372-380. doi:10.1016/0966-842X(94)90614-9 ![]() |
![]() | Duez, C., Piron-Fraipont, C., Joris, B., Dusart, J., Urdea, M.-S., Martial, J., Frère, J.-M., & Ghuysen, J.-M. (15 September 1994). Erratum for : primary structure of the streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene. European Journal of Biochemistry, 224 (3), 1079. doi:10.1111/j.1432-1033.1994.01079.x ![]() |
![]() | Fanuel, L., Granier, B., Wilkin, J.-M., Bellefroid-Bourguignon, C., Joris, B., Knowles, J., Komives, E., Van Beeumen, J., Ghuysen, J.-M., & Frère, J.-M. (29 August 1994). The Precursor of the Streptomyces R61 Dd-Peptidase Containing a C-Terminal Extension Is Inactive. FEBS Letters, 351 (1), 49-52. doi:10.1016/0014-5793(94)00822-1 ![]() |
![]() | Ayala, J., Goffin, C., Nguyen-Distèche, M., & Ghuysen, J.-M. (15 August 1994). Site-directed mutagenesis of penicillin-binding protein 3 of Escherichia coli: role of Val-545. FEMS Microbiology Letters, 121 (2), 251-256. doi:10.1111/j.1574-6968.1994.tb07106.x ![]() |
![]() | Ghuysen, J.-M., Lamotte-Brasseur, J., Joris, B., & Shockman, G. D. (28 March 1994). Binding Site-Shaped Repeated Sequences of Bacterial Wall Peptidoglycan Hydrolases. FEBS Letters, 342 (1), 23-28. doi:10.1016/0014-5793(94)80577-6 ![]() |
![]() | Fraipont, C., Adam, M., Nguyen-Distèche, M., Keck, W., Van Beeumen, J., Ayala, J. A., Granier, B., Hara, H., & Ghuysen, J.-M. (10 February 1994). Engineering and Overexpression of Periplasmic Forms of the Penicillin-Binding Protein 3 of Escherichia Coli. Biochemical Journal, 298 (1), 189-195. doi:10.1042/bj2980189 ![]() |
![]() | Englebert, S., Charlier, P., Fonze, E., To'th, Y., Vermeire, M., Van Beeumen, J., Grandchamps, J., Hoffmann, K., Leyh-Bouille, M., Nguyen-Distèche, M., & Ghuysen, J.-M. (1994). Crystallization and X-ray diffraction study of the Streptomyces K15 penicillin-binding DD-transpeptidase. Journal of Molecular Biology, 241 (2), 295-7. doi:10.1006/jmbi.1994.1504 ![]() |
![]() | Dive, G., Dehareng, D., & Ghuysen, J.-M. (1994). Detailed Study of a Molecule in a Molecule N-Acetyl-L-Tryptophanamide in a Active-Site Model of Alpha-Chymotrypsin. Journal of the American Chemical Society, 116 (6), 2548-2556. doi:10.1021/ja00085a039 ![]() |
![]() | Granier, B., Jamin, M., Adam, M., Galleni, M., Lakaye, B., Zorzi, W., Grandchamps, J., Wilkin, J.-M., Fraipont, C., Joris, B., Duez, C., Nguyen-Distèche, M., Coyette, J., Leyh-Bouille, M., Dusart, J., Christians, L., Frère, J.-M., & Ghuysen, J.-M. (1994). Serine-Type D-Ala-D-Ala Peptidases and Penicillin-Binding Proteins. Methods in Enzymology, 244, 249-266. doi:10.1016/0076-6879(94)44021-2 ![]() |
![]() | Goffin, C., Ayala, J. A., Nguyen-Distèche, M., & Ghuysen, J.-M. (01 November 1993). Site-directed mutagenesis of dicarboxylic acid residues of the penicillin-binding module of the Escherichia coli penicillin-binding protein 3. FEMS Microbiology Letters, 113 (3), 247-251. doi:10.1111/j.1574-6968.1993.tb06522.x ![]() |
![]() | Hourdou, M.-L., Guinand, M., Vacheron, M.-J., Denoroy, L., Duez, C., Englebert, S., Joris, B., Weber, G., Ghuysen, J.-M., & Michel, G. (01 June 1993). Characterization of the Sporulation-Related Gamma-D-Glutamyl-(L)Meso-Diaminopimelic-Acid-Hydrolysing Peptidase I of Bacillus Sphaericus NCTC 9602 as a Member of the Metallo(Zinc) Carboxypeptidase A Family. Modular Design of the Protein. Biochemical Journal, 292 (Pt 2), 563-570. doi:10.1042/bj2920563 ![]() |
![]() | Piras, G., Raze, D., el Kharroubi, A., Hastir, D., Englebert, S., Coyette, J., & Ghuysen, J.-M. (May 1993). Cloning and Sequencing of the Low-Affinity Penicillin-Binding Protein 3r-Encoding Gene of Enterococcus Hirae S185: Modular Design and Structural Organization of the Protein. Journal of Bacteriology, 175 (10), 2844-2852. doi:10.1128/jb.175.10.2844-2852.1993 ![]() |
![]() | Dehareng, D., Dive, G., & Ghuysen, J.-M. (1993). Analytical calculation of the electrostatic interaction energy within the CNDO framework. International Journal of Quantum Chemistry, 46 (6), 711-734. doi:10.1002/qua.560460605 ![]() |
![]() | Malissard, M., Duez, C., Guinand, M., Vacheron, M.-J., Michel, G., Marty, N., Joris, B., Thamm, I., & Ghuysen, J.-M. (1993). Sequence of a gene encoding a (poly ManA) alginate lyase active on Pseudomonas aeruginosa alginate. FEMS Microbiology Letters, 110 (1), 101-106. doi:10.1111/j.1574-6968.1993.tb06302.x ![]() |
![]() | Dehareng, D., Dive, G., & Ghuysen, J.-M. (1993). Polarization-corrected electrostatic potentials of aromatic compounds. Journal of the American Chemical Society, 115 (15), 6877-6882. doi:10.1021/ja00068a052 ![]() |
![]() | Dive, G., Dehareng, D., & Ghuysen, J.-M. (1993). Energy Analysis on Small to Medium Sized H-Bonded Complexes. Theoretica Chimica Acta, 85 (6), 409-421. doi:10.1007/BF01112981 ![]() |
![]() | Palomeque-Messia, P., Quittre, V., Leyh-Bouille, M., Nguyen-Distèche, M., Gershater, C. J., Dacey, I. K., Dusart, J., Van Beeumen, J., & Ghuysen, J.-M. (15 November 1992). Secretion by Overexpression and Purification of the Water-Soluble Streptomyces K15 Dd-Transpeptidase/Penicillin-Binding Protein. Biochemical Journal, 288 (1), 87-91. doi:10.1042/bj2880087 ![]() |
![]() | Zhu, Y., Englebert, S., Joris, B., Ghuysen, J.-M., Kobayashi, T., & Lampen, J.-O. (01 October 1992). Structure, function, and fate of the BlaR signal transducer involved in induction of β-lactamase in Bacillus licheniformis. Journal of Bacteriology, 174 (19), 6171-6178. doi:10.1128/jb.174.19.6171-6178.1992 ![]() |
![]() | Hadonou, A. M., Wilkin, J.-M., Varetto, L., Joris, B., Lamotte-Brasseur, J., Klein, D., Duez, C., Ghuysen, J.-M., & Frère, J.-M. (01 July 1992). Site-Directed Mutagenesis of the Streptomyces R61 Dd-Peptidase. Catalytic Function of the Conserved Residues around the Active Site and a Comparison with Class-a and Class-C Beta-Lactamases. European Journal of Biochemistry, 207 (1), 97-102. doi:10.1111/j.1432-1033.1992.tb17025.x ![]() |
![]() | Bourguignon-Bellefroid, C., Joris, B., Van Beeumen, J., Ghuysen, J.-M., & Frère, J.-M. (01 April 1992). Point Mutations of Two Arginine Residues in the Streptomyces R61 Dd-Peptidase. Biochemical Journal, 283 (1), 123-128. doi:10.1042/bj2830123 ![]() |
![]() | Granier, B., Duez, C., Englebert, S., Dusart, J., Dideberg, O., Van Beeumen, J., Frère, J.-M., Ghuysen, J.-M., & Lepage, S. (15 March 1992). Primary and Predicted Secondary Structures of the Actinomadura R39 Extracellular DD-Peptidase, a Penicillin-Binding Protein (PBP) Related to the Escherichia coli PBP4. Biochemical Journal, 282 (Pt 3), 781-788. doi:10.1042/bj2820781 ![]() |
![]() | Joris, B., Englebert, S., Chu, C.-P., Kariyama, R., Daneo-Moore, L., Shockman, G. D., & Ghuysen, J.-M. (15 March 1992). Modular Design of the Enterococcus Hirae Muramidase-2 and Streptococcus Faecalis Autolysin. FEMS Microbiology Letters, 91 (3), 257-264. doi:10.1016/0378-1097(92)90707-U ![]() |
![]() | Hourdou, M.-L., Duez, C., Joris, B., Vacheron, M.-J., Guinand, M., Michel, G., & Ghuysen, J.-M. (01 March 1992). Cloning and nucleotide sequence of the gene encoding the γ-D-glutamyl-L-diamino acid endopeptidase II of Bacillus sphaericus. FEMS Microbiology Letters, 91 (2), 165-170. doi:10.1016/0378-1097(92)90678-H ![]() |
![]() | Bourguignon-Bellefroid, C., Wilkin, J.-M., Joris, B., Aplin, R. T., Houssier, C., Prendergast, F. G., Van Beeumen, J., Ghuysen, J.-M., & Frère, J.-M. (01 March 1992). Importance of the Two Tryptophan Residues in the Streptomyces R61 Exocellular Dd-Peptidase. Biochemical Journal, 282 (Pt 2), 361-367. doi:10.1042/bj2820361 ![]() |
![]() | Hadonou, A. M., Jamin, M., Adam, M., Joris, B., Dusart, J., Ghuysen, J.-M., & Frère, J.-M. (01 March 1992). Importance of the His-298 Residue in the Catalytic Mechanism of the Streptomyces R61 Extracellular Dd-Peptidase. Biochemical Journal, 282 (Pt 2), 495-500. doi:10.1042/bj2820495 ![]() |
![]() | Lamotte-Brasseur, J., Jacob-Dubuisson, F., Dive, G., Frère, J.-M., & Ghuysen, J.-M. (10 February 1992). Streptomyces albus G serine β-lactamase. Probing of the catalytic mechanism via molecular modelling of mutant enzymes. Biochemical Journal, 282 (Pt 1), 189-195. doi:10.1042/bj2820189 ![]() |
![]() | Dive, G., Dehareng, D., Culot, P., & Ghuysen, J.-M. (1992). Energy hypersurface local properties of the O2HF-1 rearrangement. Chemical Physics Letters, 195 (2-3), 189-193. doi:10.1016/0009-2614(92)86134-4 ![]() |
![]() | Dehareng, D., Dive, G., & Ghuysen, J.-M. (1992). Influence of the Counterpoise Correction on the Optimized Relativi Degrees of Freedom in the H-Bonded Complex Water-Formamide. Theoretica Chimica Acta, 81 (4-5), 281-290. doi:10.1007/BF01118568 ![]() |
![]() | Culot, P., Dive, G., Nguyen, V. H., & Ghuysen, J.-M. (1992). A quasi-Newton algorithm for first-odrer saddle-point location. Theoretica Chimica Acta, 82, 189-205. doi:10.1007/BF01113251 |
![]() | el Kharroubi, A., Jacques, P., Piras, G., Van Beeumen, J., Coyette, J., & Ghuysen, J.-M. (01 December 1991). The Enterococcus Hirae R40 Penicillin-Binding Protein 5 and the Methicillin-Resistant Staphylococcus Aureus Penicillin-Binding Protein 2' Are Similar. Biochemical Journal, 280 (Pt 2), 463-469. doi:10.1042/bj2800463 ![]() |
![]() | Joris, B., Ledent, P., Dideberg, O., Fonze, E., Lamotte-Brasseur, J., Kelly, J. A., Ghuysen, J.-M., & Frère, J.-M. (November 1991). Comparison of the Sequences of Class a β-lactamase and of the Secondary Structure Elements of Penicillin-Recognizing Proteins. Antimicrobial Agents and Chemotherapy, 35 (11), 2294-2301. doi:10.1128/AAC.35.11.2294 ![]() |
![]() | Palomeque-Messia, P., Englebert, S., Leyh-Bouille, M., Nguyen-Distèche, M., Duez, C., Houba, S., Dideberg, O., Van Beeumen, J., & Ghuysen, J.-M. (01 October 1991). Amino Acid Sequence of the Penicillin-Binding Protein/DD-Peptidase of Streptomyces K15. Predicted Secondary Structures of the Low Mr Penicillin-Binding Proteins of Class A. Biochemical Journal, 279 (Pt 1), 223-230. doi:10.1042/bj2790223 ![]() |
![]() | Lamotte-Brasseur, J., Dive, G., Dideberg, O., Charlier, P., Frère, J.-M., & Ghuysen, J.-M. (01 October 1991). Mechanism of acyl transfer by the class A serine β-lactamase of Streptomyces albus G. Biochemical Journal, 279 (Pt 1), 213-221. doi:10.1042/bj2790213 ![]() |
![]() | Jacques, P., el Kharroubi, A., Van Beeumen, J., Piras, G., Coyette, J., & Ghuysen, J.-M. (01 August 1991). Mode of Membrane Insertion and Sequence of a 32-Amino Acid Peptide Stretch of the Penicillin-Binding Protein 4 of Enterococcus Hirae. FEMS Microbiology Letters, 66 (2), 119-123. doi:10.1111/j.1574-6968.1991.tb04851.x ![]() |
![]() | Ambler, R. P., Coulson, A. F. W., Frère, J.-M., Ghuysen, J.-M., Joris, B., Forsman, M., Levesque, R. C., Tiraby, G., & Waley, S. G. (15 May 1991). A standard numbering scheme for the class A beta-lactamases. Biochemical Journal, 276 (Pt 1), 269-270. doi:10.1042/bj2760269 ![]() |
![]() | Ghuysen, J.-M. (March 1991). Recherche fondamentale et médecine. Revue Médicale de Liège, 46 (3), 115-122. ![]() |
![]() | Dehareng, D., Dive, G., & Ghuysen, J.-M. (1991). Polarization correction to the electrostatic potential at the CNDO and the ab initio level. Influence of the basis set expansion. Theoretica Chimica Acta, 79 (2), 141-152. doi:10.1007/BF01127102 ![]() |
![]() | Lamotte, J., Dive, G., & Ghuysen, J.-M. (1991). Conformational analysis of β and γ-lactam antibiotics. European Journal of Medicinal Chemistry, 26 (1), 43-50. doi:10.1016/0223-5234(91)90211-5 ![]() |
![]() | Adam, M., Damblon, C., Jamin, M., Zorzi, W., Dusart, V., Galleni, M., El Kharroubi, A., Piras, G., Spratt, B. G., Keck, W., Coyette, J., Ghuysen, J.-M., NGuyen-Distèche, M., & Frère, J.-M. (1991). Acyltransferase activities of the high-molecular-mass essential penicillin-binding proteins. Biochemical Journal, 279 (Part 2), 601-604. doi:10.1042/bj2790601 ![]() |
![]() | Ghuysen, J.-M. (1991). Serine β-lactamases and penicillin-binding proteins. Annual Review of Microbiology, 45, 37-67. doi:10.1146/annurev.mi.45.100191.000345 ![]() |
![]() | Ghuysen, J.-M. (1991). Protéines liant la pénicilline et les B-lactamases. Mecanisme, structure et évolution. Journal de Pharmacie de Belgique, 46 (1), 7-8. ![]() |
![]() | Piras, G., El Kharroubi, A., van Beeumen, J., Coeme, E., Coyette, J., & Ghuysen, J.-M. (01 December 1990). Characterization of an Enterococcus Hirae Penicillin-Binding Protein 3 with Low Penicillin Affinity. Journal of Bacteriology, 172 (12), 6856-6862. doi:10.1128/jb.172.12.6856-6862.1990 ![]() |
![]() | Urabe, H., Lenzini, M. V., Mukaide, M., Dusart, J., Nakano, M. M., Ghuysen, J.-M., & Ogawara, H. (01 November 1990). β-Lactamase expression in Streptomyces cacaoi. Journal of Bacteriology, 172 (11), 6427-6434. doi:10.1128/jb.172.11.6427-6434.1990 ![]() |
![]() | Jacob, F., Joris, B., Dideberg, O., Dusart, J., Ghuysen, J.-M., & Frère, J.-M. (October 1990). Engineering a Novel β-Lactamase by a Single Point Mutation. Protein Engineering, 4 (1), 79-86. doi:10.1093/protein/4.1.79 ![]() |
![]() | Ghuysen, J.-M. (October 1990). Membrane Topology, Structure, and Functions of the Penicillin-Interactive Proteins. Biotechnology and Applied Biochemistry, 12 (5), 468-472. doi:10.1111/j.1470-8744.1990.tb00114.x ![]() |
![]() | Duez, C., Lakaye, B., Houba, S., Dusart, J., & Ghuysen, J.-M. (01 September 1990). Cloning, Nucleotide Sequence and Amplified Expression of the Gene Encoding the Extracellular Metallo (Zn) Dd-Peptidase of Streptomyces Albus G. FEMS Microbiology Letters, 71 (1-2), 215-219. doi:10.1016/0378-1097(90)90059-Y ![]() |
![]() | Piron-Fraipont, C., Lenzini, M. V., Dusart, J., & Ghuysen, J.-M. (1990). Transcriptional Analysis of the dd-Peptidase/Penicillin-Binding Protein-Encoding dac Gene of Streptomyces R61: Use of the Promoter and Signal Sequences in a Secretion Vector. Molecular and General Genetics, (223), 114-120. doi:10.1007/BF00315803 ![]() |
![]() | Lamotte-Brasseur, J., Dive, G., Dehareng, D., & Ghuysen, J.-M. (24 July 1990). Electrostatic potential maps at the quantum chemistry level of the active sites of the serine peptidases, α-chymotrypsin and subtilisin. Journal of Theoretical Biology, 145 (2), 183-98. doi:10.1016/S0022-5193(05)80124-9 ![]() |
![]() | Joris, B., Ledent, P., Kobayashi, T., Lampen, J.-O., & Ghuysen, J.-M. (15 June 1990). Expression in Escherichia Coli of the Carboxy Terminal Domain of the Blar Sensory-Transducer Protein of Bacillus Licheniformis as a Water-Soluble Mr 26,000 Penicillin-Binding Protein. FEMS Microbiology Letters, 58 (1), 107-113. doi:10.1016/0378-1097(90)90111-3 ![]() |
![]() | Joris, B., Dive, G., Henriques, A., Piggot, P. J., & Ghuysen, J.-M. (March 1990). The Life-Cycle Proteins Roda of Escherichia Coli and Spove of Bacillus Subtilis Have Very Similar Primary Structures. Molecular Microbiology, 4 (3), 513-517. doi:10.1111/j.1365-2958.1990.tb00618.x ![]() |
![]() | Zhu, Y.-F., Curran, I. H. A., Joris, B., Ghuysen, J.-M., & Lampen, J. O. (01 February 1990). Identification of BlaR, the signal transducer for β-lactamase production in Bacillus licheniformis, as a penicillin-binding protein with strong homology to the OXA-2 β-lactamase (class D) of Salmonella typhimurium. Journal of Bacteriology, 172 (2), 1137-1141. doi:10.1128/jb.172.2.1137-1141.1990 ![]() |
![]() | Houba, S., Willem, S., Duez, C., Molitor, C., Dusart, J., Frère, J.-M., & Ghuysen, J.-M. (December 1989). Nucleotide sequence of the gene encoding the active-site serine β-lactamase from Actinomadura R39. FEMS Microbiology Letters, 65 (3), 241-246. doi:10.1111/j.1574-6968.1989.tb03667.x ![]() |
![]() | Laible, G., Hakenbeck, R., Sicard, M. A., Joris, B., & Ghuysen, J.-M. (01 October 1989). Nucleotide sequences of the pbpX genes encoding the penicillin-binding proteins 2x from Streptococcus pneumoniae R6 and a cefotaxime-resistant mutant, C506. Molecular Microbiology, 3 (10), 1337-1348. doi:10.1111/j.1365-2958.1989.tb00115.x ![]() |
![]() | El Kharroubi, A., Piras, G., Jacques, P., Szabo, I., Van Beeumen, J., Coyette, J., & Ghuysen, J.-M. (01 September 1989). Active-Site and Membrane Topology of the Dd-Peptidase/Penicillin-Binding Protein No. 6 of Enterococcus Hirae (Streptococcus Faecium) A.T.C.C. 9790. Biochemical Journal, 262 (2), 457-462. doi:10.1042/bj2620457 ![]() |
![]() | Leyh-Bouille, M., Vanbeeumen, J., Renier-Pirlot, S., Joris, B., Nguyen-Distèche, M., & Ghuysen, J.-M. (1989). The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region. Biochemical Journal, 260 (2), 601-604. doi:10.1042/bj2600601 ![]() |
![]() | Dehareng, D., Dive, G., Lamotte-Brasseur, J., & Ghuysen, J.-M. (1989). Numerical computation of the electrostatic interaction energy between methanol and the dyad water-imidazole. Theoretica Chimica Acta, 76 (2), 85-94. doi:10.1007/BF00532126 ![]() |
![]() | Kelly, J. A., Knox, J. R., Zhao, H. C., Frère, J.-M., & Ghuysen, J.-M. (1989). Crystallographic mapping of β-lactams bound to a D-alanyl-D-alanine peptidase target enzyme. Journal of Molecular Biology, 209 (2), 281-295. doi:10.1016/0022-2836(89)90277-5 ![]() |
![]() | Fraipont, C., Duez, C., Matagne, A., Molitor, C., Dusart, J., Frère, J.-M., & Ghuysen, J.-M. (1989). Cloning and amplified expression in Streptomyces lividans of the gene encoding the extracellular β-lactamase of Actinomadura R39. Biochemical Journal, 262 (3), 849-854. doi:10.1042/bj2620849 ![]() |
![]() | Joris, B., Ghuysen, J.-M., Dive, G., Renard, A., Dideberg, O., Charlier, P., Frère, J.-M., Kelly, J. A., Boyington, J., Moews, P. C., & Knox, J. (01 March 1988). The Active-Site-Serine Penicillin-Recognizing Enzymes as Members of the Streptomyces R61 Dd-Peptidase Family. Biochemical Journal, 250 (2), 313-324. doi:10.1042/bj2500313 ![]() |
Kelly, J. A., Knox, J. R., Moews, P. C., Frère, J.-M., & Ghuysen, J.-M. (01 March 1988). Using X-ray diffraction results and computer graphics to design beta-lactams. Kansenshogaku zasshi, 62 Suppl, 182-191. ![]() |
![]() | Ferreira, L. C., Schwarz, U., Keck, W., Charlier, P., Dideberg, O., & Ghuysen, J.-M. (15 January 1988). Properties and crystallization of a genetically engineered, water-soluble derivative of penicillin-binding protein 5 of Escherichia coli K12. European Journal of Biochemistry, 171 (1-2), 11-16. doi:10.1111/j.1432-1033.1988.tb13751.x ![]() |
![]() | Bartholomé-De Belder, J., Nguyen-Distèche, M., Houba-Herin, N., Ghuysen, J.-M., Maruyama, I. N., Hara, H., Hirota, Y., & Inouye, M. (1988). Overexpression, solubilization and refolding of a genetically engineered derivative of the penicillin-binding protein 3 of Escherichia coli K12. Molecular Microbiology, 2 (4), 519-525. doi:10.1111/j.1365-2958.1988.tb00058.x ![]() |
![]() | Curtis, N. A. C., Bennett, P. M., Nicholas, R., Spratt, B. G., Jacoby, G. A., Levesque, R. C., Tomasz, A., Ghuysen, J.-M., Courvalin, P., Broomesmith, J., Wiedemann, B., Mitsuitashi, S., Richmond, M. H., Franklin, T. J., & Bush, K. (1988). Biochemistry of beta-lactamases and penicillin-binding proteins - Discussion. Reviews of Infectious Diseases, 10 (4), 739-742. ![]() |
![]() | Ghuysen, J.-M. (1988). Bacterial Active-Site Serine Penicillin-Interactive Proteins and Domains: Mechanism, Structure, and Evolution. Reviews of Infectious Diseases, 10 (4), 726-732. doi:10.1093/clinids/10.4.726 ![]() |
Lenzini, M. V., Ishihara, H., Dusart, J., Ogawara, H., Joris, B., Van Beeumen, J., Frère, J.-M., & Ghuysen, J.-M. (1988). Nucleotide sequence of the gene encoding the active-site serine β-lactamase from Streptomyces cacaoi. FEMS Microbiology Letters, 49 (3), 371-376. doi:10.1111/j.1574-6968.1988.tb02760.x ![]() |
![]() | Frère, J.-M., Joris, B., Dideberg, O., Charlier, P., & Ghuysen, J.-M. (1988). Penicillin-recognizing enzymes. Biochemical Society Transactions, 16 (6), 934-938. doi:10.1042/bst0160934 ![]() |
![]() | Varetto, L., Frère, J.-M., & Ghuysen, J.-M. (10 December 1987). The importance of the negative charge of β-lactam compounds for the inactivation of the active-site serine DD-peptidase of Streptomyces R61. FEBS Letters, 225 (1-2), 218-222. doi:10.1016/0014-5793(87)81161-4 ![]() |
![]() | Lenzini, M. V., Nojima, S., Dusart, J., Ogawara, H., Dehottay, P., Frère, J.-M., & Ghuysen, J.-M. (October 1987). Cloning and amplified expression in Streptomyces lividans of the gene encoding the extracellular β-lactamase from Streptomyces cacaoi. Journal of General Microbiology, 133 (10), 2915-2920. ![]() |
![]() | Dehottay, P., Dusart, J., De Meester, F., Joris, B., Van Beeumen, J., Erpicum, T., Frère, J.-M., & Ghuysen, J.-M. (15 July 1987). Nucleotide sequence of the gene encoding the Streptomyces albus G β-lactamase precursor. European Journal of Biochemistry, 166 (2), 345-350. doi:10.1111/j.1432-1033.1987.tb13521.x ![]() |
![]() | Varetto, L., Frère, J.-M., Nguyen-Distèche, M., Ghuysen, J.-M., & Houssier, C. (02 February 1987). The pH dependence of the active-site serine DD-peptidase of Streptomyces R61. European Journal of Biochemistry, 162 (3), 525-531. doi:10.1111/j.1432-1033.1987.tb10671.x ![]() |
![]() | Leyh-Bouille, M., Nguyen-Distèche, M., Bellefroid-Bourguignon, C., & Ghuysen, J.-M. (01 February 1987). Effects of thiol reagents on Streptomyces K15 DD-peptidase-catalysed reactions. Biochemical Journal, 241 (3), 893-897. doi:10.1042/bj2410893 ![]() |
![]() | Duez, C., Fraipont, C., Joris, B., Dusart, J., Urdea, M. S., Martial, J., Frère, J.-M., & Ghuysen, J.-M. (1987). Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene. European Journal of Biochemistry, 162, 509-518. doi:10.1111/j.1432-1033.1987.tb10669.x ![]() |
![]() | Demeester, F., Joris, B., Lenzini, M. V., Dehottay, P., Erpicium, T., Dusart, J., Klein, D., Ghuysen, J.-M., Frère, J.-M., & Vanbeeumen, J. (1987). The active sites of the β-lactamases of Streptomyces cacaoi and Streptomyces albus G. Biochemical Journal, 244 (2), 427-432. doi:10.1042/bj2440427 ![]() |
![]() | Dideberg, O., Charlier, P., Wery, J.-P., Dehottay, P., Dusart, J., Erpicum, T., Frère, J.-M., & Ghuysen, J.-M. (1987). The crystal structure of the β-lactamase of Streptomyces albus G at 0.3 nm resolution. Biochemical Journal, 245 (3), 911-913. doi:10.1042/bj2450911 ![]() |
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Ghuysen, J.-M., Frère, J.-M., Leyh-Bouille, M., Nguyen-Distèche, M., Coyette, J., Dusart, J., Joris, B., Duez, C., Dideberg, O., Charlier, P., Dive, G., & Lamotte-Brasseur, J. (1984). Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics. Scandinavian Journal of Infectious Diseases, 42, 17-37. ![]() |
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Ghuysen, J.-M., Frère, J.-M., Leyh-Bouille, M., Coyette, J., Dusart, J., Nguyen-Distèche, M., Marquet, A., & Duez, C. (1979). Interaction between penicillin and its enzyme target. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 2, 287-300. ![]() |
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![]() | Ghuysen, J.-M. (1975). Paroi bactérienne, membrane cytoplasmique et pénicilline. Microbia, A (2). |
![]() | Johnson, K., Duez, C., Frère, J.-M., & Ghuysen, J.-M. (1975). Beta-lactamases (Actinomycetes species). Methods in Enzymology, XLIII, 687-698. doi:10.1016/0076-6879(75)43134-2 ![]() |
![]() | Ghuysen, J.-M., Frère, J.-M., Leyh-Bouille, M., Dusart, J., Nguyen-Distèche, M., Coyette, J., Perkins, H., Nieto, M., & Marquet, A. (1975). Bacterial transpeptidases and penicillin. Bulletin de l'Institut Pasteur, 73 (1), 101-140. ![]() |
![]() | Frère, J.-M., Leyh-Bouille, M., Ghuysen, J.-M., & Perkins, H. R. (16 December 1974). Interaction between beta-lactam antibiotics and exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61. European Journal of Biochemistry, 50 (1), 203-214. doi:10.1111/j.1432-1033.1974.tb03889.x ![]() |
![]() | Frère, J.-M., Moreno, R., & Ghuysen, J.-M. (01 October 1974). Molecular weight, amino acid composition and physicochemical properties of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39. Biochemical Journal, 143 (1), 233-240. doi:10.1042/bj1430233 ![]() |
![]() | Wietzerbin, J., Das, B. C., Petit, J.-F., Lederer, E., Leyh-Bouille, M., & Ghuysen, J.-M. (13 August 1974). Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria. Biochemistry, 13 (17), 3471-3476. doi:10.1021/bi00714a008 ![]() |
![]() | Marquet, A., Dusart, J., Ghuysen, J.-M., & Perkins, H.-R. (01 August 1974). Membrane-bound transpeptidase and penicillin binding sites in Streptomyces strain R61. European Journal of Biochemistry, 46 (3), 515-523. doi:10.1111/j.1432-1033.1974.tb03645.x ![]() |
![]() | Ghuysen, J.-M., Reynolds, P. E., Perkins, H. R., Frère, J.-M., & Moreno, R. (04 June 1974). Effects of donor and acceptor peptides on concomitant hydrolysis and transfer reactions catalyzed by the exocellular DD-carboxypeptidase-transpeptidase from Streptomyces R39. Biochemistry, 13 (12), 2539-2547. doi:10.1021/bi00709a010 ![]() |
![]() | Coyette, J., Perkins, H. R., Polacheck, I., Shockman, G. D., & Ghuysen, J.-M. (15 May 1974). Membrane-bound DD-carboxypeptidase and LD-transpeptidase of Streptococcus faecalis ATCC 9790. European Journal of Biochemistry, 44 (2), 459-468. doi:10.1111/j.1432-1033.1974.tb03504.x ![]() |
![]() | Pollock, J. J., Nguyen-Distèche, M., Ghuysen, J.-M., Linder, R., & Salton, M. R. (10 May 1974). The DD-carboxypeptidase-transpeptidase system in Escherichia coli mutant strain. Annals of the New York Academy of Sciences, 235, 225-235. doi:10.1111/j.1749-6632.1974.tb43268.x ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Frère, J.-M., Dusart, J., Marquet, A., Perkins, H. R., & Nieto, M. (10 May 1974). The penicillin receptor in Streptomyces. Annals of the New York Academy of Sciences, 235, 236-268. doi:10.1111/j.1749-6632.1974.tb43269.x ![]() |
![]() | Nguyen-Distèche, M., Ghuysen, J.-M., Pollock, J. J., Reynolds, P., Perkins, H. R., Coyette, J., & Salton, M. R. (01 February 1974). Enzymes involved in wall peptide crosslinking in Escherichia coli K12, strain 44. European Journal of Biochemistry, 41 (3), 447-455. doi:10.1111/j.1432-1033.1974.tb03286.x ![]() |
![]() | Nguyen-Distèche, M., Pollock, J. J., Ghuysen, J.-M., Puig, J., Reynolds, P., Perkins, H.-R., Coyette, J., & Salton, M.-R.-J. (01 February 1974). Sensitivity to ampicillin and cephalothin of enzymes involved in wall peptide crosslinking in Escherichia coli K12, strain 44. European Journal of Biochemistry, 41 (3), 457-463. doi:10.1111/j.1432-1033.1974.tb03287.x ![]() |
![]() | Ghuysen, J.-M. (1974). Substrate Requirements of Glycosidases for Lytic Activity on Bacterial Walls. Lysozyme, 185-193. |
![]() | Pollock, J. J., Nguyen-Distèche, M., Ghuysen, J.-M., Coyette, J., Linder, R., Salton, M. R., Kim, K. S., Perkins, H.-R., & Reynolds, P. (1974). Fractionation of the DD-carboxypeptidase-transpeptidase activities solubilized from membranes of Escherichia coli K12, strain 44. European Journal of Biochemistry, 41 (3), 439-446. doi:10.1111/j.1432-1033.1974.tb03285.x ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Frère, J.-M., Dusart, J., Coyette, J., Nguyen-Distèche, M., & Duez, C. (1974). Comment la Pénicilline tue les bactéries. Annales de Microbiologie, 125 B (2), 209-210. ![]() |
![]() | Frère, J.-M., Ghuysen, J.-M., Reynolds, P. E., & Moreno, R. (1974). Binding of beta-lactam antibiotics to the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R39. Biochemical Journal, 143 (1), 241-249. doi:10.1042/bj1430241 ![]() |
![]() | Nieto, M., Perkins, H. R., Frère, J.-M., & Ghuysen, J.-M. (01 November 1973). Fluorescence and circular dichroism studies on the Streptomyces R61 DD-carboxypeptidase-transpeptidase. Penicillin binding by the enzyme. Biochemical Journal, 135 (3), 493-505. doi:10.1042/bj1350493 ![]() |
![]() | Frère, J.-M., Ghuysen, J.-M., Perkins, H. R., & Nieto, M. (01 November 1973). Molecular weight and amino acid composition of the exocellular DD-carboxypeptidase-transpeptidase of Streptomyces R61. Biochemical Journal, 135 (3), 463-468. doi:10.1042/bj1350463 ![]() |
![]() | Frère, J.-M., Ghuysen, J.-M., Perkins, H. R., & Nieto, M. (01 November 1973). Kinetics of concomitant transfer and hydrolysis reactions catalysed by the exocellular DD-carboxypeptidase-transpeptidase of streptomyces R61. Biochemical Journal, 135 (3), 483-492. doi:10.1042/bj1350483 ![]() |
![]() | Martin, J.-P., Fleck, J., Mock, M., & Ghuysen, J.-M. (05 October 1973). The wall peptidoglycans of Neisseria perflava, Moraxella glucidolytica, Pseudomonas alcaligenes and Proteus vulgaris strain P18. European Journal of Biochemistry, 38 (2), 301-306. doi:10.1111/j.1432-1033.1973.tb03062.x ![]() |
![]() | Perkins, H. R., Nieto, M., Frère, J.-M., Leyh-Bouille, M., & Ghuysen, J.-M. (01 April 1973). Streptomyces DD-carboxypeptidases as transpeptidases. The specificity for amino compounds acting as carboxyl acceptors. Biochemical Journal, 131 (4), 707-718. doi:10.1042/bj1310707 ![]() |
![]() | Dusart, J., Marquet, A., Ghuysen, J.-M., Frère, J.-M., Moreno, R., Leyh-Bouille, M., Johnson, K., Lucchi, C., Perkins, H. R., & Nieto, M. (02 February 1973). DD-carboxypeptidase-transpeptidase and killing site of β-lactam antibiotics in Streptomyces strains R39, R61, and K11. Antimicrobial Agents and Chemotherapy, 3 (2), 181-187. doi:10.1128/AAC.3.2.181 ![]() |
![]() | Johnson, K., Dusart, J., Campbell, J. N., & Ghuysen, J.-M. (01 February 1973). Exocellular β-lactamases of Streptomyces albus G and strains R39 and K11. Antimicrobial Agents and Chemotherapy, 3 (2), 289-298. doi:10.1128/AAC.3.2.289 ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Campbell, J. N., Frère, J.-M., Duez, C., Nieto, M., & Perkins, H. R. (1973). Structure of the wall peptidoglycan of streptomyces R39 and the specificity profile of its exocellular DD-carboxypeptidase-transpeptidase for peptide acceptors. Biochemistry, 12 (7), 1243-1251. doi:10.1021/bi00731a001 ![]() |
![]() | Nieto, M., Perkins, H. R., Leyh-Bouille, M., Frère, J.-M., & Ghuysen, J.-M. (01 January 1973). Peptide inhibitors of Streptomyces DD-carboxypeptidases. Biochemical Journal, 131 (1), 163-171. doi:10.1042/bj1310163 ![]() |
![]() | Vacheron, M.-J., Guinand, M., Michel, G., & Ghuysen, J.-M. (18 August 1972). Structural investigations on cell walls of Nocardia sp. The wall lipid and peptidoglycan moieties of Nocardia kirovani. European Journal of Biochemistry, 29 (1), 156-166. doi:10.1111/j.1432-1033.1972.tb01970.x ![]() |
![]() | Leyh-Bouille, M., Nakel, M., Frère, J.-M., Johnson, K., Ghuysen, J.-M., Nieto, M., & Perkins, H. R. (28 March 1972). Penicillin-sensitive DD-carboxypeptidases from Streptomyces strains R39 and K11. Biochemistry, 11 (7), 1290-1298. doi:10.1021/bi00757a027 ![]() |
![]() | Pollock, J. J., Ghuysen, J.-M., Linder, R., Salton, M. R. J., Perkins, H. R., Nieto, M., Leyh-Bouille, M., Frère, J.-M., & Johnson, K. (01 March 1972). Transpeptidase activity of Streptomyces D-alanyl-D carboxypeptidases. Proceedings of the National Academy of Sciences of the United States of America, 69 (3), 662-666. doi:10.1073/pnas.69.3.662 ![]() |
![]() | Nakel, M., Ghuysen, J.-M., & Kandler, O. (25 May 1971). Wall peptidoglycan in Aerococcus viridans strains 201 Evans and ATCC 11563 and in Gaffkya homari strain ATCC 10400. Biochemistry, 10 (11), 2170-2175. doi:10.1021/bi00787a033 ![]() |
![]() | Leyh-Bouille, M., Coyette, J., Ghuysen, J.-M., Idczak, J., Perkins, H. R., & Nieto, M. (25 May 1971). Penicillin-sensitive DD-carboxypeptidase from Streptomyces strain R 61. Biochemistry, 10 (11), 2163-2170. doi:10.1021/bi00787a032 ![]() |
![]() | Wheat, R.-W., & Ghuysen, J.-M. (March 1971). Occurrence of glucomuramic acid in gram-positive bacteria. Journal of Bacteriology, 105 (3), 1219-1221. ![]() |
![]() | Fleck, J., Mock, M., Minck, R., & Ghuysen, J.-M. (1971). The cell envelope in Proteus vulgaris P 18 : Isolation and characterization of the peptidoglycan component. Biochimica et Biophysica Acta. Biomembranes, 223 (3), 489-503. doi:10.1016/0005-2736(71)90149-0 ![]() |
![]() | Leyh-Bouille, M., Ghuysen, J.-M., Bonaly, R., Nieto, M., Perkins, H. R., Schleifer, K. H., & Kandler, O. (21 July 1970). Substrate requirements of the Streptomyces albus G DD carboxypeptidase. Biochemistry, 9 (15), 2961-2970. doi:10.1021/bi00817a005 ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., Bonaly, R., Nieto, M., Perkins, H. R., Schleifer, K. H., & Kandler, O. (21 July 1970). Isolation of DD carboxypeptidase from Streptomyces albus G culture filtrates. Biochemistry, 9 (15), 2955-2961. doi:10.1021/bi00817a004 ![]() |
![]() | Leyh-Bouille, M., Bonaly, R., Ghuysen, J.-M., Tinelli, R., & Tipper, D. (21 July 1970). LL-diaminopimelic acid containing peptidoglycans in walls of Streptomyces sp. and of Clostridium perfringens (type A). Biochemistry, 9 (15), 2944-2952. doi:10.1021/bi00817a002 ![]() |
![]() | Leyh-Bouille, M., Ghuysen, J.-M., Nieto, M., Perkins, H. R., Schleifer, K. H., & Kandler, O. (21 July 1970). On the Streptomyces albus G DD carboxypeptidase mechanism of action of penicillin, vancomycin, and ristocetin. Biochemistry, 9 (15), 2971-2975. doi:10.1021/bi00817a006 ![]() |
![]() | Coyette, J., & Ghuysen, J.-M. (21 July 1970). Structure of the walls of Lactobacillus acidophilus strain 63 AM Gasser. Biochemistry, 9 (15), 2935-2943. doi:10.1021/bi00817a001 ![]() |
![]() | Coyette, J., & Ghuysen, J.-M. (21 July 1970). Wall autolysin of Lactobacillus acidophilus strain 63 AM gasser. Biochemistry, 9 (15), 2952-2955. doi:10.1021/bi00817a003 ![]() |
![]() | Tinelli, R., Shilo, M., Laurent, M., Ghuysen, J.-M., & Prévot, A.-R. (Other coll.). (25 May 1970). De la présence d'un glycopeptide dans la paroi de Bdello-vibrio vacteriovirus. Comptes Rendus de l'Académie des Sciences. Série III. Sciences de la Vie, 270, 2600-2602. ![]() |
![]() | Ghuysen, J.-M., & Leyh-Bouille, M. (1970). Biochemistry of the Bacterial Wall Peptidoglycan in Relation to the Membrane. FEBS Symposium, 20, 59-69. |
![]() | Azuma, I., Thomas, D. W., Adam, A., Ghuysen, J.-M., Bonaly, R., Petit, J.-F., & Lederer, E. (1970). Occurrence of N-glycolylmuramic acid in bacterial cell walls: a preliminary survey. Biochimica et Biophysica Acta - General Subjects, 208 (3), 444-451. doi:10.1016/0304-4165(70)90217-5 ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., & Salton, M. R. J. (01 August 1969). The primary structure of bacterial wall peptidoglycans. Journal of General Microbiology, 57 (3). ![]() |
![]() | Petit, J. F., Adam, A., Wietzerbin-Falszpan, J., Lederer, E., & Ghuysen, J.-M. (22 May 1969). Chemical structure of the cell wall of Mycobacterium smegmatis. I. Isolation and partial characterization of the peptidoglycan. Biochemical and Biophysical Research Communications, 35 (4), 478-485. doi:10.1016/0006-291x(69)90371-4 ![]() |
![]() | Guinand, M., Ghuysen, J.-M., Schleifer, K. H., & Kandler, O. (01 January 1969). The peptidoglycan in walls of Butyribacterium rettgeri. Biochemistry, 8 (1), 200-207. doi:10.1021/bi00829a029 ![]() |
![]() | Van Heijenoort, J., Elbaz, L., Dezelee, P., Petit, J.-F., Bricas, E., & Ghuysen, J.-M. (01 January 1969). Structure of the meso-diaminopimelic acid containing peptidoglycans in Escherichia coli B and Bacillus megaterium KM. Biochemistry, 8 (1), 207-213. doi:10.1021/bi00829a030 ![]() |
Ghuysen, J.-M., Dierickx, L., Coyette, J., Leyh-Bouille, M., Guinand, M., & Campbell, J.-N. (01 January 1969). An improved technique for the preparation of Streptomyces peptidases and N-acetylmuramyl-l-alanine amidase active on bacterial wall peptidoglycans. Biochemistry, 8 (1), 213-222. doi:10.1021/bi00829a031 ![]() |
![]() | Campbell, J. N., Leyh-Bouille, M., & Ghuysen, J.-M. (01 January 1969). Characterization of the Micrococcus lysodeikticus type of peptidoglycan in walls of other Micrococcaceae. Biochemistry, 8 (1), 193-200. doi:10.1021/bi00829a028 ![]() |
![]() | Ghuysen, J.-M. (01 December 1968). Use of bacteriolytic enzymes in determination of wall structure and their role in cell metabolism. Bacteriological Reviews, 32 (4 Pt 2), 425-464. doi:10.1128/mmbr.32.4_pt_2.425-464.1968 ![]() |
![]() | Coyette, J., & Ghuysen, J.-M. (01 June 1968). Structure of the cell wall of Staphylococcus aureus, strain Copenhagen. IX. Teichoic acid and phage adsorption. Biochemistry, 7 (6), 2385-2389. doi:10.1021/bi00846a048 ![]() |
![]() | Ghuysen, J.-M., Bricas, E., Lache, M., & Leyh-Bouille, M. (01 April 1968). Structure of the Cell Walls of Micrococcus lysodeikticus. III. Isolation of a New Peptide Dimer, Nα-[L-Alanyl-γ-(α-D-glutamyl-glycine )]-L-lysyl-D-alanyl-Nα- [L-alanyl-γ-(α-D-glutamyl-glycine)]-L-lysyl-D-alanine. Biochemistry, 7 (4), 1450-1460. doi:10.1021/bi00844a030 ![]() |
![]() | Ghuysen, J.-M. (1968). Bacterial cell walls. New Comprehensive Biochemistry, 26A, 53-104. ![]() |
Ghuysen, J.-M., Munoz, E., Leyh-Bouille, M., Petit, J., & Heymann, H. (1968). Structure and synthesis of the peptide subunits of the cell walls of three gram-positive bacteria. Colloques Internationaux du Centre National de la Recherche Scientifique, 286-292. ![]() |
![]() | Ghuysen, J.-M. (1968). Structure and biosynthesis of the bacterial wall peptidoglycan. Colloques Internationaux du Centre National de la Recherche Scientifique, 175, 283-292. ![]() |
![]() | Munoz, E., Ghuysen, J.-M., & Heymann, H. (01 December 1967). Cell walls of Streptococcus pyogenes, type 14. C polysaccharide-peptidoglycan and G polysaccharide-peptidoglycan complexes. Biochemistry, 6 (12), 3659-2670. doi:10.1021/bi00864a007 ![]() |
![]() | Ghuysen, J.-M., Bricas, E., Leyh-Bouille, M., Lache, M., & Shockman, G. D. (01 August 1967). The peptide N alpha-(L-alanyl-D-isoglutaminyl)-N epsilon-(D-isoasparaginyl)-L-lysyl-D-alanine and the disaccharide N-acetylglucosaminyl-beta-1,4-N-acetylmuramic acid in cell wall peptidoglycan of Streptococcus faecalis strain ATCC 9790. Biochemistry, 6 (8), 2607-2619. doi:10.1021/bi00860a044 ![]() |
![]() | Bricas, E., Ghuysen, J.-M., & Dezelee, P. (01 August 1967). The Cell Wall Peptidoglycan of Bacillus megaterium KM. I. Studies on the Stereochemistry of α,α'-Diaminopimelic Acid. Biochemistry, 6 (8), 2598-2607. doi:10.1021/bi00860a043 ![]() |
![]() | Strominger, J. L., & Ghuysen, J.-M. (14 April 1967). Mechanisms of enzymatic bacteriaolysis. Cell walls of bacteri are solubilized by action of either specific carbohydrases or specific peptidases. Science, 156 (772), 213-221. doi:10.1126/science.156.3772.213 ![]() |
![]() | Tipper, D. J., Katz, W., Strominger, J. L., & Ghuysen, J.-M. (01 March 1967). Substituents on the alpha-carboxyl group of D-glutamic acid in the peptidoglycan of several bacterial cell walls. Biochemistry, 6 (3), 921-929. doi:10.1021/bi00855a036 ![]() |
Munoz, E., Ghuysen, J.-M., Leyh-Bouille, M., Petit, J.-F., & Tinelli, R. (October 1966). Structural variations in bacterial cell wall peptidoglycans studied with Streptomyces F1 endo-N-acetylmuramidase. Biochemistry, 5 (10), 3091–3098. doi:10.1021/bi00874a002 ![]() |
![]() | Leyh-Bouille, M., Ghuysen, J.-M., Tipper, D. J., & Stominger, J. L. (01 October 1966). Structure of the cell wall of Micrococcus lysodeikticus. I. Study of the structure of the glycan. Biochemistry, 5 (10), 3079-3090. doi:10.1021/bi00874a001 ![]() |
![]() | Petit, J.-F., Munoz, E., & Ghuysen, J.-M. (01 August 1966). Peptide cross-links in bacterial cell wall peptidoglycans studied with specific endopeptidases from Streptomyces albus G. Biochemistry, 5 (8), 2764-2776. doi:10.1021/bi00872a037 ![]() |
![]() | Ghuysen, J.-M., Munoz, E., Leyh-Bouille, M., Petit, J.-F., Heymann, H., Bricas, E., & Lefrancier, P. (1966). Peptide subunit. N(super x)-(L-alanyl-D-isoglutaminyl)L-lysyl-D-alanine in cell wall peptidoglycans of Staphylococcus aureus strain Copenhagen, Micrococcus roseus R27, and Streptococcus pyogenes group A, typ 14. Biochemistry, 5 (12), 3748-3764. ![]() |
![]() | Ghuysen, J.-M., Tipper, D. J., & Strominger, J. L. (1966). Enzymes that degrade bacterial cell walls. Methods in Enzymology, 8, 685-699. doi:10.1016/0076-6879(66)08124-2 ![]() |
![]() | Ghuysen, J.-M., Petit, J.-F., Munoz, E., Leyh-Bouille, M., & Dierickx, L. (1966). Action des enzymes bactériolytiques, autres que le lysozyme, sur le peptidoglycane des parois cellulaires bactériennes. Exposés Annuels de Biochimie Médicale, 101-110. ![]() |
![]() | Ghuysen, J.-M., Tipper, D., Birge, C., & Strominger, J. (October 1965). Structure of the Cell Wall of Staphylococcus aureus StrainCopenhagen. VI. The Soluble Glycopeptide and Its Sequential Degradatuib by Peptidases. Biochemistry, 4 (10), 2245-2254. ![]() |
![]() | Ghuysen, J.-M., Dierickx, L., Leyh-Bouille, M., Strominger, J., Bricas, E., & Nicot, C. (October 1965). Structure of the Cell Wall of Staphylococcus aureus StrainCopenhagen. V. Isolation of Peptidases Active on the Peptide Moiety of the Cell Walls of Some Gram-Positive Bacteria. Biochemistry, 4 (10), 2237-2244. ![]() |
Tipper, D. J., Ghuysen, J.-M., & Strominger, J. L. (1965). Structure of the cell wall of Staphylococcus aureus, strain Copenhagen. III. Further studies of the disaccharides. Biochemistry, 4 (3), 468-473. doi:10.1021/bi00879a015 ![]() |
![]() | Ghuysen, J.-M., Tipper, D. J., & Strominger, J. L. (1965). Structure of the Cell Wall of Staphylococcus Aureus, Strain Copenhagen. IV. The Teichoic Acid-Glycopeptide Complex. Biochemistry, 4, 474-485. doi:10.1021/bi00879a016 ![]() |
![]() | Tipper, D. J., Strominger, J. L., & Ghuysen, J.-M. (06 November 1964). Staphylolytic Enzyme from Chalaropsis: Mechanism of Action. Science, 146, 781-782. doi:10.1126/science.146.3645.781 ![]() |
![]() | Ghuysen, J.-M., & Strominger, J. L. (01 September 1963). Structure of the Cell Wall of Staphylococcus Aureus, Strain Copenhagen. II. Separation and Structure of Disaccharides. Biochemistry, 2, 1119-1125. doi:10.1021/bi00905a036 ![]() |
![]() | Ghuysen, J.-M., & Strominger, J. L. (01 September 1963). Structure of the Cell Wall of Staphylococcus Aureus, Strain Copenhagen. I. Preparation of Fragments by Enzymatic Hydrolysis. Biochemistry, 2 (5), 1110-1119. doi:10.1021/bi00905a035 ![]() |
![]() | Strominger, J. L., & Ghuysen, J.-M. (14 August 1963). On the Linkage between Teichoic Acid and the Glycopeptide in the Cell Wall of Staphylococcus Aureus. Biochemical and Biophysical Research Communications, 12 (5), 418-424. doi:10.1016/0006-291X(63)90117-7 ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., & Dierickx, L. (24 September 1962). Structure des parois de Bacillus megaterium KM II. étude des complexes mucopeptidique et phosphomucopolysaccharidique. Biochimica et Biophysica Acta, 63, 297-307. doi:10.1016/0006-3002(62)90683-2 ![]() |
![]() | Dierickx, L., & Ghuysen, J.-M. (26 March 1962). Purification de la [beta]-(1-4)-N-acétylhexosaminidase sécrétée par Streptomyces albus G et active sur les parois de Micrococus lysodeikticus. Biochimica et Biophysica Acta, 58, 7-18. doi:10.1016/0006-3002(62)90811-9 ![]() |
![]() | Ghuysen, J.-M., Leyh-Bouille, M., & Dierickx, L. (1962). Structure des parois de Bacillus megaterium KM I. Isolement de l'amidase et d'un enzyme nouveau sécrétés par Streptomyces albus G et actifs sur les parois de Bacillus megaterium KM et de Micrococcus lysodeikticus. Biochimica et Biophysica Acta, 63 (2), 286-296. doi:10.1016/0006-3002(62)90682-0 ![]() |
![]() | Ghuysen, J.-M. (03 March 1961). Complexe acide téichoique-mucopeptide des parois cellulaires de Bacillus megaterium KM. Biochimica et Biophysica Acta, 50 (3), 413-429. doi:10.1016/0006-3002(61)90001-4 ![]() |
![]() | Ghuysen, J.-M. (1961). Précisions sur la structure des complexes disaccharide-peptide libérés des parois de Micrococcus lysodeikticus sous l'action des β (I → 4) N-acetylhexosaminidases. Biochimica et Biophysica Acta, 47 (3), 561-568. doi:10.1016/0006-3002(61)90551-0 ![]() |
![]() | Salton, M. R. J., & Ghuysen, J.-M. (04 December 1960). Acetylhexosamine compounds enzymically released from Micrococcus lysodeikticus cell walls: III. The structure of di- and tetra-saccharides released from cell walls by lysozyme and Streptomyces F1 enzyme. Biochimica et Biophysica Acta, 45, 355-363. doi:10.1016/0006-3002(60)91458-X ![]() |
![]() | Ghuysen, J.-M. (03 June 1960). Acetylhexosamine compounds enzymically released from micrococcus lysodeikticus cell walls: II. Enzymic sensitivity of purified acetylhexosamine and acetylhexosamine-peptide complexes. Biochimica et Biophysica Acta, 40, 473-480. doi:10.1016/0006-3002(60)91388-3 ![]() |
![]() | Ghuysen, J.-M., & Salton, M. R. J. (03 June 1960). Acetylhexosamine compounds enzymically released from Micrococcus lysodeikticus cell walls: I. Isolation and composition of acetylhexosamine and acetylhexosamine-peptide complexes. Biochimica et Biophysica Acta, 40, 462-472. doi:10.1016/0006-3002(60)91387-1 ![]() |
![]() | Ghuysen, J.-M. (1960). Chimie de la structure des parois cellulaires bactériennes. Industrie Chimique Belge, 9, 1077-1089. |
![]() | Charlier, R., Prost, M., Dierickx, L., Ghuysen, J.-M., Urbain, M., & Singier, J. (01 March 1959). Le carbamate de propynylcyclohexanol étude pharmacologique et biologique. Archives Internationales de Pharmacodynamie et de Thérapie, 119 (1-2), 264-274. ![]() |
![]() | Deltour, G. H., Ghuysen, J.-M., & Claus, A. (1959). Effet de la mescaline, du lsd 25 et de dérivés de l'adrenochrome sur la décarboxlyase glutamique du cerveau. Biochemical Pharmacology, 1 (4), 267-272. doi:10.1016/0006-2952(59)90113-3 ![]() |
![]() | Salton, M. R. J., & Ghuysen, J.-M. (1959). The structure of di- and tetra-saccharides released from cell walls by lysozyme and streptomyces F1 enzyme and the [beta] (1-->4) N-acetylhexosaminidase activity of these enzymes. Biochimica et Biophysica Acta, 36 (2), 552-554. doi:10.1016/0006-3002(59)90205-7 ![]() |
Ghuysen, J.-M. (01 April 1957). Activités bacteriolytiques de l'actinomycetine de Streptomyces albus G. Archives Internationales de Physiologie et de Biochimie, 65 (2), 173-305. ![]() |
![]() | Salton, M. R. J., & Ghuysen, J.-M. (1957). Action de l'actinomycetine sur les parois cellulaires bacteriennes. Biochimica et Biophysica Acta, 24 (1), 160-173. doi:10.1016/0006-3002(57)90159-2 ![]() |
![]() | Ghuysen, J.-M., & Welsch, M. (10 October 1954). Action de l'actinomycetine sur le fibrinogene et la fibrine. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 148 (19-20), 1694-1697. ![]() |
![]() | Ghuysen, J.-M., & Welsch, M. (Other coll.). (01 July 1954). Concentration et purification des principes bacteriolytiques de l'actinomycetine par chromatographie sur corps microbiens. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 148 (13-14), 1283-1287. ![]() |
![]() | Ghuysen, J.-M., Leger, G., & Welsch, M. (Other coll.). (01 April 1954). L'activité antibiotique du type actinomycetine chez les Streptomyces. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 148 (19-20), 1691-1693. ![]() |
![]() | Ghuysen, J.-M., & Welsch, M. (Other coll.). (01 April 1954). Activite pneumolytique de l'actinomycetine. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 148 (7-8), 729-732. ![]() |
![]() | Bergamini, L., Ghuysen, J.-M., & Welsch, M. (01 April 1954). L'activité antibiotique du type actinomycetine chez les Streptomyces. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 148 (7-8), 733-736. ![]() |
![]() | Ghuysen, J.-M., & Welsch, M. (01 August 1953). Influence des ions bivalents et de la témperature sur la production et les activités des principes bacteriolytiques de l'actinomycetine. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 147 (15-18), 1502-1505. ![]() |
![]() | Ghuysen, J.-M. (01 April 1953). Dualité des principes bactériolytiques de l'actinomycetine. Archives Internationales de Physiologie, 61 (2), 259-260. doi:10.3109/13813455309147728 |
![]() | Welsch, M., & Ghuysen, J.-M. (1953). Activité streptolytique de l'actinomycetine. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 147 (19-20), 1659-1662. ![]() |
![]() | Ghuysen, J.-M., & Welsch, M. (Other coll.). (01 November 1952). Analyse et purification de l'actinomycetine par absorption. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 146 (21-22), 1812-1815. ![]() |
Ghuysen, J.-M. (01 August 1952). L'activité staphylolytique de l'actinomycétine. Comptes Rendus des Séances de la Société de Biologie et de ses Filiales, 146 (15-16), 1268-1271. |
![]() | Ghuysen, J.-M., & Desreux, V. (1952). VIII. Analyse chimique et électrotitrimétrique de l'acide ribonucléique de la levure. Bulletin des Sociétés Chimiques Belges, 61, 181-202. ![]() |
![]() | Desreux, V., & Ghuysen, J.-M. (1951). VI. La polydispersité de l'acide ribonucléique de la levure. Bulletin des Sociétés Chimiques Belges, 60 (7-8), 410-423. ![]() |
![]() | Ghuysen, J.-M. (November 1950). Etude de l'homogénéité de l'acide ribonucléique de la levure. Bulletin des Sociétés Chimiques Belges, 59 (août-septembre), 490-507. ![]() |
![]() | Duez, C., Thamm, I., Sapunaric, F., Coyette, J., & Ghuysen, J.-M. (1998). The Division and Cell Wall Gene Cluster of Enterococcus Hirae S185. DNA Sequence: the Journal of DNA Sequencing and Mapping, 9 (3), 149-161. doi:10.3109/10425179809072190 ![]() |
![]() | Fontana, R., Canepari, P., & Ghuysen, J.-M. (1996). Foreword. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 2 (1), 5-R5. doi:10.1089/mdr.1996.2.v ![]() |
![]() | Granier, B., Duez, C., Lepage, S., Englebert, S., Dusart, J., Dideberg, O., Van Baumeen, J., Frère, J.-M., & Ghuysen, J.-M. (1992). Correction: Primary and predicted secondary structure of the actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the escherichia coli PBP4 (Biochemical Journal(1992)282(786)). Biochemical Journal, 282 (Part 3), 981-982. doi:10.1042/bj2860981c ![]() |
![]() | Ghuysen, J.-M. (1989). The rigid matrix of bacterial-cell walls - a citation classic commentary on the use of bacteriolytic enzymes in determination of wall structure and their role in cell-metabolism by Ghuyssen,J.M. Current Contents. Agriculture, Biology and Environmental Sciences, (25), 17. ![]() |
Knox, J. R., DeLucia, M. L., Murthy, N. S., Kelly, J. A., Moews, P. C., Frère, J.-M., & Ghuysen, J.-M. (15 January 1979). Crystallographic data for a penicillin receptor : exocellular DD-carboxypeptidase-transpeptidase from Streptomyces R61 [letter to the editor]. Journal of Molecular Biology, 127 (2), 217-218. doi:10.1016/0022-2836(79)90241-9 ![]() |
![]() | Ghuysen, J.-M. (02 March 1964). Alkaline degradation of the phosphomucopolysaccharide from cell walls of Bacillus megaterium KM. Biochimica et Biophysica Acta, 83 (1), 132-134. doi:10.1016/0926-6526(64)90063-1 ![]() |
![]() | Ghuysen, J.-M. (01 September 1957). Les activités antimicrobiennes des détergents. Revue Médicale de Liège, 12 (17), 457-464. ![]() |
Delfosse, P., Ongena, M., Jacques, P., Ghuysen, J.-M., & Thonart, P. (April 1995). Pyoverdine-Mediated Uptake of iron in Pseudomonas putida BTP1 : involvement of a 100 KD IROMP. Poster session presented at International Conference on Bioiron, Asheville N.C., United States. |