[en] Objectives: To determine effects of training and racing on muscle oxidative phosphorylation (OXPHOS) and electron transport system (ETS) capacities in horses with high-resolution respirometry (HRR).
Research Center/Unit :
CORD - Centre de l'Oxygène, Recherche et Développement - ULiège Centre Européen du Cheval de Mont-le-Soie
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Votion, Dominique ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Fraipont, Audrey ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie
Amory, Hélène ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Médecine interne des équidés
Ceusters, Justine ; Université de Liège - ULiège > Centre de l'oxygène : Recherche et développement (C.O.R.D.)
de la Rebière de Pouyade, Geoffroy ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Franck, Thierry ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Mouithys-Mickalad, Ange ; Université de Liège - ULiège > Centre de l'oxygène : Recherche et développement (C.O.R.D.)
Niesten, Ariane ; Université de Liège - ULiège > Centre de l'oxygène : Recherche et développement (C.O.R.D.)
Serteyn, Didier ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Language :
English
Title :
Alterations in mitochondrial respiratory function in response to endurance training and endurance racing
Alternative titles :
[fr] Modification de la fonction mitochondriale musculiare équine en réponse à l'entraînement et aux courses d'endurance
Publication date :
2010
Journal title :
Equine Veterinary Journal
ISSN :
0425-1644
eISSN :
2042-3306
Publisher :
Equine Veterinary Journal Ltd, Newmarket Suffolk, United Kingdom
Volume :
42
Issue :
38
Pages :
268-274
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
DGA - Région wallonne. Direction générale de l'Agriculture
D'Angelis, F.H., Ferraz, G.C., Boleli, I.C., Lacerda-Neto, J.C. and Queiroz-Neto, A. (2005) Aerobic training, but not creatine supplementation, alters the gluteus medius muscle. J. anim. Sci. 83, 579-585.
Essen-Gustavsson, B. and Jensen-Waern, M. (2002) Effect of an endurance race on muscle amino acids, pro- and macroglycogen and triglycerides. Equine vet. J., Suppl. 33, 209-213.
Essen-Gustavsson, B., Karlstrom, K. and Lindholm, A. (1984) Fibre types, enzyme activities and substrate utilisation in skeletal muscles of horses competing in endurance rides. Equine vet. J. 16, 197-202.
Essén-Gustavsson, B., Gottlieb-Vedi, M. and Lindholm, A. (1999) Muscle adenine nucleotide degradation during submaximal treadmill exercise to fatigue. Equine vet. J., Suppl. 30, 298-302.
Evans, D.L. and Golland, L.C. (1996) Accuracy of Accusport for measurement of lactate concentrations in equine blood and plasma. Equine vet. J. 28, 398-402.
Gnaiger, E. (2003) Oxygen conformance of cellular respiration. A perspective of mitochondrial physiology. Adv. expt. Med. Biol. 543, 39-55.
Gnaiger, E. (2009) Capacity of oxidative phosphorylation in human skeletal muscle: new perspectives of mitochondrial physiology. Int. J. Biochem. Cell Biol. 41, 1837-1845.
Gnaiger, E., Kuznetsov, A.V., Schneeberger, S., Seiler, R., Brandacher, G., Steurer, W. and Margreiter, R. (2000) Mitochondria in the cold. In: Life in the Cold, Eds: G. Heldmaier and M. Klingenspor, Springe Heidelberg, New York. pp 431-442.
Kim, J.S., Hinchcliff, K.W., Yamaguchi, M., Beard, L.A., Markert, C.D. and Devor, S.T. (2005) Exercise training increases oxidative capacity and attenuates exercise-induced ultrastructural damage in skeletal muscle of aged horses. J. appl. Physiol. 98, 334-342.
Kline, K.H. and Bechtel, P.J. (1988) Changes in the metabolic profile of the equine gluteus medius as a function of sampling depth. Comp. Biochem. Physiol. A Comp. Physiol. 91, 815-819.
Kuznetsov, A., Schneeberger, S., Seiler, R., Brandacher, G., Mark, W., Steurer, W., Saks, V., Usson, Y., Margreiter, R. and Gnaiger, E. (2004) Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion. Am. J. Physiol. Heart Circ. Physiol. 286, H1633-H1641.
Letellier, T., Malgat, M., Coquet, M., Moretto, B., Parrot-Roulaud, F. and Mazat, J.P. (1992) Mitochondrial myopathy studies on permeabilized muscle fibers. Pediatr. Res. 32, 17-22.
Lindholm, A. and Piehl, K. (1974) Fibre composition, enzyme activity and concentrations of metabolites and electrolytes in muscles of Standardbred horses. Acta vet. Scand. 15, 287-309.
Lindner, A., Dag, S., Marti-Korff, S., Quiroz-Rothe, E., Lopez Rivero, J.L. and Drommer, W. (2002) Effects of repeated biopsying on muscle tissue in horses. Equine vet. J. 34, 619-624.
Lopez-Rivero, J.L., Morales-Lopez, J.L., Galisteo, A.M. and Aguera, E. (1991) Muscle fibre type composition in untrained and endurance-trained Andalusian and Arab horses. Equine vet. J. 23, 91-93.
Lopez-Rivero, J.L., Agüera, E., Monterde, J.G., Vivo, J. and Rodríguez-Barbudo, M.V. (1992) Skeletal muscle fiber size in untrained and endurance-trained horses. Am. J. vet. Res. 53, 847-850.
Rivero, J.L.L. (1996) Muscle biopsy as a tool for assessing muscular adaptation to training in horses. Am. J. vet. Res. 57, 1412-1416.
Rivero, J.L.L. (2007) A scientific background for skeletal muscle conditioning in equine practice. J. vet. Med. A Physiol. Pathol. Clin. Med. 54, 321-332.
Rivero, J.L.L., Ruz, M.C., Serrano, A.L. and Diz, A.M. (1995) Effects of a 3 months endurance Training programme on skeletal muscle histochemistry in Andalusian Arabian and Anglo-Arabian horses. Equine vet. J. 27, 51-59.
Robert, C., Goachet, A.-G., Fraipont, A., Votion, D.-M., Van Erck, E. and Leclerc, J.-L. (2010) Hydration and electrolyte balance in horses during an endurance season. Equine vet. J., Suppl. (in press).
Serrano, A.L., Petrie, J.L., Rivero, J.L. and Hermanson, J.W. (1996) Myosin isoforms and muscle fiber characteristics in equine gluteus medius muscle. Anat. Rec. 244, 444-451.
Serrano, A.L., Quiroz-Rothe, E. and Rivero, J.L.L. (2000) Early and long-term changes of equine skeletal muscle in response to endurance training and detraining. Pflugers. Arch. 441, 263-274.
Snow, D.H. and Guy, P.S. (1976) Percutaneous needle muscle biopsy in the horse. Equine vet. J. 8, 150-155.
Van Den Hoven, R., Wensing, T., Breukink, H.J., Meijer, A.E. and Kruip, T.A. (1985) Variation of fiber types in the triceps brachii, longissimus dorsi, gluteus medius, and biceps femoris of horses. Am. J. vet. Res. 46, 939-941.
Veksler, V.I., Kuznetsov, A.V., Sharov, V.G., Kapelko, V.I. and Saks, V.A. (1987) Mitochondrial respiratory parameters in cardiac tissue: a novel method of assessment by using saponin-skinned fibers. Biochim. Biophys. Acta 892, 191-196.
Votion, D.M., Navet, R., Lacombe, V.A., Sluse, F., Essen-Gustavsson, B., Hinchcliff, K.W., Rivero, J.L.L., Serteyn, D. and Valberg, S. (2007) Muscle energetics in exercising horses. Equine comp. Exerc. Physiol. 4, 105-118.
