[en] We studied the effect of mild hypothermic cardiopulmonary bypass (30 degrees C) on the EEG Bispectral Index in 10 patients undergoing elective CABG. BIS was recorded at 11 event-related time points during the procedure. After a significant decrease at the induction of anaesthesia, BIS was not further modified during the procedure. BIS was neither affected by surgical stimulation nor by CPB and mild hypothermia. We conclude that we did not find any reason to preclude the use of BIS to assess the hypnotic effects of anaesthetics during normothermic or mild hypothermic CPB.
Disciplines :
Anesthesia & intensive care
Author, co-author :
DEWANDRE, Pierre-Yves ; Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
Hans, Pol ; Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Bonhomme, Vincent ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Brichant, Jean-François ; Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Lamy, Maurice ; Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Language :
English
Title :
Effects of Mild Hypothermic Cardiopulmonary Bypass on Eeg Bispectral Index
Doi M., Gairai R. J., Mantzaridis H., Kenny G. N. C., Effects of cardiopulmonary bypass and hypothermia on electroencephalographic variables, ANESTHESIA, 52, 1048-1055, 1997.
Dowd N. P., Cheng D. C., Karski J. M., Wong D. T., Carrol Munro J. A., Sandler A. N., Intraoperative awareness in fast-track cardiac anesthesia, ANESTHESIOLOGY, 89, 1068-1073, 1998.
England M. R., McColl S. H., Manberg P. J., Clinical utility of bispectral index (BIS) during cardiac surgery. ANESTH. ANALG., 82, S 101, 1996.
England M. R., Murphy M. C., Court M., How much is enough: Titrating to the bispectral index during cardiac anesthesia, ANESTH. ANALG., 84, S73, 1997.
Gravlee G. P., Anesthetic management of cardiopulmonary bypass, ASA ANNUAL REFRESHER COURSE LECTURES, 142, 1-7, 1998.
Hager P., Schmidlin D., Schmid E. R., Bispectral index EEG during hypothermic and normothermic cardiopulmonary bypass, BR. J. ANAESTH., 80, A74, 1998.
Hayashida M., Chinzei M., Uchida K., Hanaoka K., Bispectral index as an indicator of cerebral function during profound hypothermia, ANESTHESIOLOGY, 91, A611, 1999.
Kochs E., Electrophysiological monitoring and mild hypothermia, J. NEUROSURG. ANESTH., 7, 222-228, 1995.
Laussen P. C., Mc Gowan F. X., Sullivan L. J., Murphy J. A., Bispectral index monitoring in children during mild hypothermic cardiopulmonary bypass, ANESTHESIOLOGY, 89: A925, 1998.
Muravchick S., Deep body thermometry during general anesthesia, ANESTHESIOLOGY, 58, 271-275, 1983.
Phillips A. A., Mc Lean R. F., Devitt J. H., et al., Recall of intraoperative events after general anesthesia and cardiopulmonary bypass, CAN. J. ANAESTH., 40, 922-926, 1993.
Robinson J., Charlton J., Seal R., Spady D., Joffres M. R., Oesophageal, rectal, axillary, tympanic and pulmonary artery temperatures during cardiac surgery, CAN. J. ANESTH., 45, 317-323, 1998.
Rosow C., Manberg P. J., Bispectral Index Monitoring, ANESTH. CLIN. NORTH. AM., 2, 89-107, 1998.
Sebel P. S., Central nervous system monitoring during open heart surgery an update, J. CARDIOTHOR. VASC. ANESTH., 12 (suppl.), 3-8, 1998.
Stone J. G., Young W. L., Smith C. R., Solomon R. A., Wald A., Ostapkovieh N., Shrebniek D. B., Do standard monitoring sites reflect true brain temperature when profound hypothermia is rapidly induced and reversed ?, ANESTHESIOLOGY, 82: 344-351, 1995.
Whitby J. D., Dankin L. J., Cerebral,oesophageal and nasopharyogeal temperature, BR. J. ANAESTH., 43: 673-676, 1971.