[en] Long COVID is a complex condition characterized by persistent symptoms, including cognitive difficulties and fatigue, which significantly impact daily functioning. Although various intervention strategies inspired by approaches used in the rehabilitation of other neurological conditions have been developed to address these issues, evidence of their efficacy in Long COVID populations remains limited. This study aimed to compare the effectiveness for cognitive complaints of two psychoeducational interventions-one focused on cognitive difficulties and the other on affective symptoms in Long COVID patients with cognitive problems. COVCOG (Long COVID: treatment of cognitive difficulties) is a randomized controlled trial using a parallel two-group design. Long COVID patients underwent neuropsychological assessments at pre-, 2- and 8-month post-intervention. The intervention comprised four 90-min sessions of either a cognitive-focused or an affective-focused psychoeducational programme. The effects were measured on cognitive complaints (primary outcome), cognitive performance, fatigue, sleep difficulties, quality of life, psychological distress, and impact on work and daily activities (secondary outcomes). Linear mixed models (LMMs) were used. One hundred and thirty Long COVID patients were randomized. One hundred and twenty-two (mean age: 47 ± 10; 69.7% female) were included (63 in the cognitive group and 59 in the affective group). The low dropout rate (12% at 2 months and 9% at 8 months post-intervention) and the patients' substantial active engagement-92% attended all intervention sessions-assured the feasibility of both interventions. LMM analysis revealed a statistically significant improvement with time in subjective cognitive complaints, objective cognitive performance (attention, working memory and long-term memory), quality of life, fatigue, sleep, some psychological distress subscales and work impairment (all Ps < 0.03, with small to moderate effect sizes), but no group-by-time interaction, suggesting that trajectories did not differ between arms. However, some improvements are specific to one intervention or the other. Designed specifically for this population, both psychoeducative interventions provide insights into improving the management of Long COVID patients with cognitive problems. Longer treatment may be needed for more meaningful improvements. Clinicaltrials.gov: NCT05167266.
Disciplines :
Treatment & clinical psychology
Author, co-author :
Cabello Fernandez, Carmen ; Université de Liège - ULiège > Psychologie et Neuroscience Cognitives (PsyNCog)
Didone, Vincent ; Université de Liège - ULiège > Psychologie et Neuroscience Cognitives (PsyNCog)
Lesoinne, Alexia ; Université de Liège - ULiège > Département de Psychologie > Neuropsychologie de l'adulte
Slama, Hichem; Department of Neuropsychology and Speech Therapy, Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B.), Brussels 1070, Belgium ; UR2NF-Neuropsychology and Functional Neuroimaging Research Group at CRCN-Research Centre in Cognitive Neurosciences Institute, Université Libre de Bruxelles (ULB), Brussels 1050, Belgium
Fery, Patrick; Department of Neuropsychology and Speech Therapy, Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B.), Brussels 1070, Belgium
Rousseau, Anne-Françoise ; Department of Intensive Care and Burn Centre, Centre Hospitalier Universitaire de Liège, Liège 4000, Belgium
Moutschen, Michel ; Université de Liège - ULiège > GIGA > GIGA Immunobiology - Immunology & Infectious Diseases
COVCOG group
Collette, Fabienne ✱; Université de Liège - ULiège > Département de Psychologie
Willems, Sylvie ✱; Université de Liège - ULiège > Psychologie et Neuroscience Cognitives (PsyNCog)
✱ These authors have contributed equally to this work.
Language :
English
Title :
Cognitive and affective psychoeducation for Long COVID: a randomized controlled trial.
Salamanna F, Veronesi F, Martini L, Landini MP, Fini M. Post-COVID-19 syndrome: The persistent symptoms at the post-viral stage of the disease. A systematic review of the current data. Front Med (Lausanne). 2021; 8: 653516.
Post COVID-19 condition (long COVID). Accessed 4 September 2025. https://www.who.int/news-room/fact-sheets/detail/post-covid-19-condition-(long-covid)
Peluso MJ, Deeks SG. Mechanisms of long COVID and the path toward therapeutics. Cell. 2024; 187 (20): 5500-5529.
Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: Major findings, mechanisms and recommendations. Nat Rev Microbiol. 2023; 21 (3): 133-146.
Miskowiak KW, Pedersen JK, Gunnarsson DV, et al. Cognitive impairments among patients in a long-COVID clinic: Prevalence, pattern and relation to illness severity, work function and quality of life. J Affect Disord. 2023; 324: 162-169.
Liu TC, Yoo SM, Sim MS, Motwani Y, Viswanathan N, Wenger NS. Perceived cognitive deficits in patients with symptomatic SARS-CoV-2 and their association with post-COVID-19 condition. JAMA Netw Open. 2023; 6 (5): e2311974.
Kirchberger I, Peilstöcker D, Warm TD, et al. Subjective and objective cognitive impairments in non-hospitalized persons 9 months after SARS-CoV-2 infection. Viruses. 2023; 15 (1): 256.
Wahlgren C, Forsberg G, Divanoglou A, et al. Two-year follow-up of patients with post-COVID-19 condition in Sweden: A prospective cohort study. Lancet Reg Health Eur. 2023; 28: 100595.
Fernandez-de-las-Peñas C, Notarte KI, Macasaet R, et al. Persistence of post-COVID symptoms in the general population two years after SARS-CoV-2 infection: A systematic review and meta-analysis. J Infect. 2024; 88 (2): 77-88.
Carmona-Cervelló M, León-Gómez BB, Dacosta-Aguayo R, et al. Long COVID: Cognitive, balance, and retina manifestations. Front Med (Lausanne). 2024; 11: 1-12.
Cabello Fernandez C, Didone V, Slama H, et al. Profiles of individuals with long COVID reporting persistent cognitive complaints. Arch Clin Neuropsychol. 2025; 00: 1-18. doi: 10.1093/arclin/acaf064
Tavares-Júnior JWL, de Souza ACC, Borges JWP, et al. COVID-19 associated cognitive impairment: A systematic review. Cortex. 2022; 152: 77-97.
Bertuccelli M, Ciringione L, Rubega M, Bisiacchi P, Masiero S, Del Felice A. Cognitive impairment in people with previous COVID-19 infection: A scoping review. Cortex. 2022; 154: 212-230.
Evans RA, McAuley H, Harrison EM, et al. Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): A UK multicentre, prospective cohort study. Lancet Respir Med. 2021; 9 (11): 1275-1287.
Song X, Song W, Cui L, et al. A comprehensive review of the global epidemiology, clinical management, socio-economic impacts, and national responses to long COVID with future research directions. Diagnostics. 2024; 14 (11): 1-17.
Kohn L, Dauvrin M, Detollenaere J, et al. Long COVID and return to work: A qualitative study. Occup Med (Chic Ill). 2024; 74 (1): 29-36.
Mathern R, Senthil P, Vu N, Thiyagarajan T. Neurocognitive rehabilitation in COVID-19 patients: A clinical review. South Med J. 2022; 115 (3): 227-231.
Cicerone KD, Goldin Y, Ganci K, et al. Evidence-based cognitive rehabilitation: Systematic review of the literature from 2009 through 2014. Arch Phys Med Rehabil. 2019; 100 (8): 1515-1533.
Jeffay E, Ponsford J, Harnett A, et al. INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury, part III: Executive functions. J Head Trauma Rehabil. 2023; 38 (1): 52-64.
Ponsford J, Velikonja D, Janzen S, et al. INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury, part II: Attention and information processing speed. J Head Trauma Rehabil. 2023; 38 (1): 38-51.
Velikonja D, Ponsford J, Janzen S, et al. INCOG 2.0 guidelines for cognitive rehabilitation following traumatic brain injury, part V: Memory. J Head Trauma Rehabil. 2023; 38 (1): 83-102.
Fine JS, Ambrose AF, Didehbani N, et al. Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of cognitive symptoms in patients with post-acute sequelae of SARS-CoV-2 infection (PASC). PM R. 2022; 14 (1): 96-111.
Möller M, Borg K, Janson C, Lerm M, Normark J, Niward K. Cognitive dysfunction in post-COVID-19 condition: Mechanisms, management, and rehabilitation. J Intern Med. 2023; 294 (5): 563-581.
Heslot C, Azouvi P, Perdrieau V, Granger A, Lefèvre-Dognin C, Cogné M. A systematic review of treatments of post-concussion symptoms. J Clin Med. 2022; 11 (20): 6224.
De Boussard CN, Holm LW, Cancelliere C, et al. Nonsurgical interventions after mild traumatic brain injury: A systematic review. Results of the international collaboration on mild traumatic brain injury prognosis. Arch Phys Med Rehabil. 2014; (3 SUPPL): S257-S264.
Braga LW, Oliveira SB, Moreira AS, et al. Long COVID neuropsychological follow-up: Is cognitive rehabilitation relevant? NeuroRehabilitation. 2023; 53 (4): 517-534.
Hasting AS, Herzig S, Obrig H, Schroeter ML, Villringer A, Thöne-Otto AIT. The Leipzig treatment program for interdisciplinary diagnosis and therapy of neurocognitive post-COVID symptoms experiences and preliminary results. Zeitschrift fur Neuropsychologie. 2023; 34 (2): 71-83.
Assunção PF, Takahasi EHM, Amorim JAM, de Reis RL. Rehabilitation interventions in long COVID: A case report. Dement Neuropsychol. 2024; 18: e20230105.
Dutra LS, Shigaeff N. Proposed protocol for post COVID-19 cognitive rehabilitation for attention and memory. Dement Neuropsychol. 2024; 18: e20230109.
Herrera E, Blanco C, Álvarez-Mundiñano B, González-Nosti M. Neuropsychological rehabilitation improves memory and action naming in patients with post-COVID-19 syndrome. Am J Speech Lang Pathol. 2024; 33 (2): 791-799.
García-Molina A, García-Carmona S, Espiña-Bou M, Rodríguez-Rajo P, Sánchez-Carrión R, Enseñat-Cantallops A. Neuropsychological rehabilitation for post-COVID-19 syndrome: Results of a clinical programme and six-month follow up. Neurología (Engl Ed). 2024; 39 (7): 592-603.
De Groot MH, Phillips SJ, Eskes GA. Fatigue associated with stroke and other neurologic conditions: Implications for stroke rehabilitation. Arch Phys Med Rehabil. 2003; 84 (11): 1714-1720.
Brode WM, Melamed E. A practical framework for Long COVID treatment in primary care. Life Sci. 2024; 354: 122977.
Managing fatigue in adults after acquired brain injury | 48 | Neuropsy. Accessed 19 March 2025. https://www.taylorfrancis.com/chapters/edit/10.4324/9781315629537-48/managing-fatigue-adults-acquired-brain-injury-donna-malley
Ghali A, Lacombe V, Ravaiau C, et al. The relevance of pacing strategies in managing symptoms of post-COVID-19 syndrome. J Transl Med. 2023; 21 (1): 375.
Parker M, Sawant HB, Flannery T, et al. Effect of using a structured pacing protocol on post-exertional symptom exacerbation and health status in a longitudinal cohort with the post-COVID-19 syndrome. J Med Virol. 2023; 95 (1): e28373.
Kuut TA, Müller F, Csorba I, et al. Efficacy of cognitive-behavioral therapy targeting severe fatigue following coronavirus disease 2019: Results of a randomized controlled trial. Clin Infect Dis. 2023; 77 (5): 687-695.
Taquet M, Geddes JR, Husain M, Luciano S, Harrison PJ. 6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: A retrospective cohort study using electronic health records. Lancet Psychiatry. 2021; 8 (5): 416-427.
Huang L, Yao Q, Gu X, et al. 1-year outcomes in hospital survivors with COVID-19: A longitudinal cohort study. The Lancet. 2021; 398 (10302): 747-758.
Seighali N, Abdollahi A, Shafiee A, et al. The global prevalence of depression, anxiety, and sleep disorder among patients coping with post COVID-19 syndrome (long COVID): A systematic review and meta-analysis. BMC Psychiatry. 2024; 24 (1): 1-13.
Dotson VM. Unique and interactive effect of anxiety and depressive symptoms on cognitive and brain function in young and older adults. J Depress Anxiety. 2014; S1 (01): 1-23.
Poletti S, Palladini M, Mazza MG, et al. Long-term consequences of COVID-19 on cognitive functioning up to 6 months after discharge: Role of depression and impact on quality of life. Eur Arch Psychiatry Clin Neurosci. 2022; 272 (5): 773-782.
Terpstra AR, Cairncross M, Yeates KO, et al. Psychological mediators of avoidance and endurance behavior after concussion. Rehabil Psychol. 2021; 66 (4): 470-478.
Al Sayegh A, Sandford D, Carson AJ. Psychological approaches to treatment of postconcussion syndrome: A systematic review. J Neurol Neurosurg Psychiatry. 2010; 81 (10): 1128-1134.
Sullivan KA, Kaye SA, Blaine H, et al. Psychological approaches for the management of persistent postconcussion symptoms after mild traumatic brain injury: A systematic review. Disabil Rehabil. 2020; 42 (16): 2243-2251.
Ponsford J, Lee NK, Wong D, et al. Efficacy of motivational interviewing and cognitive behavioral therapy for anxiety and depression symptoms following traumatic brain injury. Psychol Med. 2016; 46 (5): 1079-1090.
Gómez-De-Regil L, Estrella-Castillo DF, Vega-Cauich J. Psychological intervention in traumatic brain injury patients. Behav Neurol. 2019; 2019: 1-8.
Huth D, Bräscher AK, Tholl S, et al. Cognitive-behavioral therapy for patients with post-COVID-19 condition (CBT-PCC): A feasibility trial. Psychol Med. 2024; 54 (6): 1122-1132.
Koller K, Kastel-Hoffmann S, Herold R, et al. A prospective non-randomized controlled trial testing the effectiveness of psychotherapeutic inpatient treatment of post-COVID-19 syndrome - Study protocol. BMC Psychol. 2024; 12 (1): 486.
Skilbeck L. Patient-led integrated cognitive behavioural therapy for management of long COVID with comorbid depression and anxiety in primary care - A case study. Chronic Illn. 2022; 18 (3): 691-701.
Compagno S, Palermi S, Pescatore V, et al. Physical and psychological reconditioning in long COVID syndrome: Results of an out-of-hospital exercise and psychological - Based rehabilitation program. Int J Cardiol Heart Vasc. 2022; 41: 101080.
Ferrario SR, Panzeri A, Cerutti P, Sacco D. The psychological experience and intervention in post-acute COVID-19 inpatients. Neuropsychiatr Dis Treat. 2021; 17: 413-422.
Hausswirth C, Schmit C, Rougier Y, Coste A. Positive impacts of a four-week neuro-meditation program on cognitive function in post-acute sequelae of COVID-19 patients: A randomized controlled trial. Int J Environ Res Public Health. 2023; 20 (2): 1-16.
Willems S, Didone V, Cabello Fernandez C, et al. COVCOG: Immediate and long-term cognitive improvement after cognitive versus emotion management psychoeducation programs - A randomized trial in COVID patients with neuropsychological difficulties. BMC Neurol. 2023; 23 (1): 307.
Randolph C, Tierney MC, Mohr E, Chase TN. The repeatable battery for the assessment of neuropsychological status (RBANS): Preliminary clinical validity. J Clin Exp Neuropsychol. 1998; 20 (3): 310-319.
Benedict RHB, Groninger L, Schretlen D, Dobraski M, Shpritz B. Revision of the brief visuospatial memory test: Studies of normal performance, reliability, and validity. Psychol Assess. 1996; 8 (2): 145-153.
Zimmermann P, Fimm B. A test battery for attentional performance. Applied neuropsychology of attention. Psychology Press; 2011.
Brickenkamp R, Schmidt-Atzert L, Liepmann D. D2-R: Test d'attention concentrée révisé. Accessed 20 March 2025. https://www.hogrefe.com/fr/shop/test-d-attention-concentree.html.
Azouvi P, Vallat-Azouvi C, Joseph PA, et al. Executive functions deficits after severe traumatic brain injury: The GREFEX study. J Head Trauma Rehabil. 2016; 31 (3): E10-E20.
Geurten M, Vincent E, Van Der Linden M, et al. Working memory assessment: Construct validity of the Brown-Peterson test. Can J Behav Sci/Revue canadienne des sciences. 2016; 48 (4): 328-336.
Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal cognitive assessment, MoCA: A brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005; 53 (4): 695-699.
Waid-Ebbs JK, Wen PS, Heaton SC, et al. The item level psychometrics of the behaviour rating inventory of executive function-adult (BRIEF-A) in a TBI sample. Brain Inj. 2012; 26 (13-14): 1646-1657.
Troyer AK, Rich JB. Psychometric properties of a new metamemory questionnaire for older adults. J Gerontol B Psychol Sci Soc Sci. 2002; 57 (1): 19-27.
Multiple Sclerosis Council for Clinical Practice Guidelines. Fatigue and multiple sclerosis: Evidence-based management strategies for fatigue in multiple sclerosis. Paralyzed Veterans of America; 1998.
Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh sleep quality Index: A new instrument for psychiatric practice and research. Psychiatry Res. 1989; 28: 193-213.
Lambert MJ, Burlingame GM, Umphress V, et al. The reliability and validity of the outcome questionnaire. Clin Psychol Psychother. 1996; 3 (4): 249-258.
Duquette RL, Dupuis G, Perrault J. A new approach for quality of life assessment in cardiac patients: Rationale and validation of the quality of life systemic inventory. Can J Cardiol. 1994; 10 (1): 106-112.
EuroQol Research Foundation. EQ-5D-5L user guide, 2019. Accessed 20 March 2025. https://euroqol.org/publications/user-guides
Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993; 4 (5): 353-365.
Levine B, Robertson IH, Clare L, et al. Rehabilitation of executive functioning: An experimental-clinical validation of goal management training. J Int Neuropsychol Soc. 2000; 6 (3): 299-312.
Cantin JF, Ouellet MC, Turcotte N, Lessard J, Potvin I, Boutin N. Le guide de l'énergie vers une meilleure gestion de la fatigue: guide de l'intervenant, outils d'évaluation. Institut de réadaptation en déficience physique de Québec; 2014. Accessed 20 March 2025. https://www.cassetete22.com/wp-content/uploads/2017/06/Guide-de-l%C3%A9nergie-Guide-de-lintervenant-Par-l%E2%80%99-IRDPQ-Quebec.pdf
Fasotti L, Kovacs F, Eling PATM, Brouwer WH. Time pressure management as a compensatory strategy training after closed head injury. Neuropsychol Rehabil. 2000; 10 (1): 47-65.
Kaplan SJ. The private practice of behavior therapy: A guide for behavioral practitioners. Springer Nature; 1986.
Dugas MJ, Gagnon F, Ladouceur R, Freeston MH. Generalized anxiety disorder: A preliminary test of a conceptual model. Behav Res Ther. 1998; 36 (2): 215-226.
Fanget F, Rouchouse B. Affirmation de soi (L'): Une méthode de thérapie. Odile Jacob; 2007.
Blairy S, Baeyens C, Wagener A. L'activation comportementale: Traitement des évitements comportementaux et de la rumination mentale. Mardaga; 2020.
Cohen J. Statistical power analysis for the behavioral sciences. Routledge; 2013.
R Core Team. R: A language and environment for statistical computing. (Version 4.1); 2021. Accessed 20 March 2025. Retrieved from https://www.R-project.org/
Maronna RA, Zamar RH. Robust estimates of location and dispersion for high-dimensional datasets. Technometrics. 2002; 44 (4): 307-317.
Gnanadesikan R, Kettenring JR. Robust estimates, residuals, and outlier detection with multiresponse data. Biometrics. 1972; 28: 81-124.
Badinlou F, Abzhandadze T, Rahimian F, Jansson-Fröjmark M, Hedman-Lagerlöf M, Lundgren T. Investigating the trajectory of post-COVID impairments: A longitudinal study in Sweden. Front Psychol. 2024; 15: 1402750.
Diana L, Regazzoni R, Sozzi M, et al. Monitoring cognitive and psychological alterations in COVID-19 patients: A longitudinal neuropsychological study. J Neurol Sci. 2023; 444: 120511.
Potter SDS, Brown RG, Fleminger S. Randomised, waiting list controlled trial of cognitive-behavioural therapy for persistent postconcussional symptoms after predominantly mild-moderate traumatic brain injury. J Neurol Neurosurg Psychiatry. 2016; 87 (10): 1075-1083.
Uiterwijk D, Stargatt R, Humphrey S, Crowe SF. The relationship between cognitive functioning and symptoms of depression, anxiety, and post-traumatic stress disorder in adults with a traumatic brain injury: A meta-analysis. Neuropsychol Rev. 2022; 32 (4): 758-806.
Navas-Otero A, Calvache-Mateo A, Calles-Plata I, et al. A lifestyle adjustments program in long COVID-19 improves symptomatic severity and quality of life. A randomized control trial. Patient Educ Couns. 2024; 122: 108180.
Ito D, Watanabe A, Takeichi S, Ishihara A, Yamamoto K. A preliminary study of work-focused cognitive behavioural group therapy for Japanese workers. Behav Cogn Psychother. 2019; 47 (2): 251-256.
Liu EN, Yang JH, Patel L, et al. Longitudinal analysis and treatment of neuropsychiatric symptoms in post-acute sequelae of COVID-19. J Neurol. 2023; 270 (10): 4661-4672.
Rass V, Beer R, Schiefecker AJ, et al. Neurological outcomes 1 year after COVID-19 diagnosis: A prospective longitudinal cohort study. Eur J Neurol. 2022; 29 (6): 1685-1696.
Davis HE, Assaf GS, McCorkell L, et al. Characterizing long COVID in an international cohort: 7 months of symptoms and their impact. EClinicalMedicine. 2021; 38: 101019.
Deng J, Zhou F, Hou W, et al. The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: A meta-analysis. Ann N Y Acad Sci. 2021; 1486 (1): 90-111.
Kerksieck P, Ballouz T, Haile SR, et al. Post COVID-19 condition, work ability and occupational changes in a population-based cohort. Lancet Reg Health - Eur. 2023; 31: 100671.
Audrit H, Beauchamp M, Tinawi S, et al. Multidimensional psychoeducative and counseling intervention (SAAM) for symptomatic patients with mild traumatic brain injury: A pilot randomized controlled trial. J Head Trauma Rehabil. 2021; 36 (4): E249-E261.
Azariah A, Watanabe T. Postconcussion syndrome assessment, management, and treatment. Elsevier Inc.; 2020.
Garrido Ardila EM, Rodríguez Mansilla J, Jiménez Palomares M, Torres Piles ST, González López-Arza MV. Cognitive rehabilitation in fibromyalgia and chronic fatigue syndrome: Current advances. In: Columbus AM, ed. Advances in psychology research. Nova Science Publishers; 2017: 1-14.
Sacks-Zimmerman A, Bergquist TF, Farr EM, Cornwell MA, Kanellopoulos D. Rehabilitation of neuropsychiatric symptoms in patients with Long COVID: Position statement. Arch Phys Med Rehabil. 2023; 104 (2): 350-354.
Espinoza C, Martella D. Cognitive functions in COVID-19 survivors, approaches strategies, and impact on health systems: A qualitative systematic review. Springer Berlin Heidelberg; 2023.
Floridia M, Giuliano M, Weimer LE, et al. Symptom profile, case and symptom clustering, clinical and demographic characteristics of a multicentre cohort of 1297 patients evaluated for long-COVID. BMC Med. 2024; 22 (1): 532.
Voruz P, Cionca A, De Alcântara I J, et al. Functional connectivity underlying cognitive and psychiatric symptoms in post-COVID-19 syndrome: Is anosognosia a key determinant? Brain Commun. 2022; 4 (2): 1-15.
Voruz P, de Alcântara IJ, Nuber-Champier A, et al. Persistence and emergence of new neuropsychological deficits following SARS-CoV-2 infection: A follow-up assessment of the Geneva COVID-COG cohort. J Glob Health. 2024; 14: 05008.
Gómez Bravo R, Infanti A, Billieux J, et al. Unmasking the psychological landscape of Long COVID: A cluster-analytical approach. Biopsychosoc Sci Med. 2025; 87 (3): 162-172.
Amsterdam D, Kupershmidt A, Avinir A, et al. Long COVID-19 Enigma: Unmasking the role of distinctive personality profiles as risk factors. J Clin Med. 2024; 13 (10): 2886.
Gloeckl R, Leitl D, Schneeberger T, Jarosch I, Koczulla AR. Rehabilitative interventions in patients with persistent post COVID-19 symptoms - A review of recent advances and future perspectives. Eur Arch Psychiatry Clin Neurosci. 2023; 274 (8): 1819-1828.
Duff EP, Zetterberg H, Heslegrave A, et al. Plasma proteomic evidence for increased Alzheimer's disease-related brain pathology after SARS-CoV-2 infection. Nat Med. 2024; 31: 797-806.
Levine KS, Leonard HL, Blauwendraat C, et al. Virus exposure and neurodegenerative disease risk across national biobanks. Neuron. 2023; 111 (7): 1086-1093.e2.
Bird M, Ouellette C, Whitmore C, et al. Preparing for patient partnership: A scoping review of patient partner engagement and evaluation in research. Health Expect. 2020; 23 (3): 523-539.
Beglinger LJ, Gaydos B, Tangphao-Daniels O, et al. Practice effects and the use of alternate forms in serial neuropsychological testing. Arch Clin Neuropsychol. 2005; 20 (4): 517-529.
Arentsen TJ, Boone KB, Lo TTY, et al. Effectiveness of the Comalli Stroop test as a measure of negative response bias. Clin Neuropsych. 2013; 27 (6): 1060-1076.
Sugarman MA, Axelrod BN. Embedded measures of performance validity using verbal fluency tests in a clinical sample. Appl Neuropsychol. 2015; 22 (2): 141-146.
Chafetz M. Reducing the probability of false positives in malingering detection of social security disability claimants detection of social security disability claimants. Clin Neuropsychol. 2011; 25: 1239-1252.
Bertrand JA, Chartrand JP, Gauthier AK, Kennepohl S. Validité de performance aux tests neuropsychologiques: Prise de position de l 'association québécoise des neuropsychologues. Neuropsychologie clinique et appliquée 2023; 5: 1-16. ().
de Erausquin GA, Zwir JI, Snyder HM, et al. Cognitive sequealae of COVID-19 is not predicted by SARS-CoV-2 variants. Alzheimer's Dement. 2023; 19 (S24): 1-2.
Saigal A, Nagoda Niklewicz C, Naidu SB, et al. Cross-sectional study evaluating the impact of SARS-CoV-2 variants on Long COVID outcomes in UK hospital survivors. BMJ Open Respir Res. 2023; 10 (1): 1-12.
Charlton BG. Medical practice and the double-blind, randomized controlled trial. Br J Gen Pract. 1991; 41 (350): 355-356.
Carey TA, Stiles WB. Some problems with randomized controlled trials and some viable alternatives. Clin Psychol Psychother. 2016; 23 (1): 87-95.
Brewin C, Bradley C. Patient preferences and randomised controlled trials. Bmj. 1989; 299: 313-315.
