Article (Scientific journals)
Towards Precritical Medical Therapy of the Abdominal Aortic Aneurysm.
MUSUMECI, Lucia; Eilenberg, Wolf; Pincemail, Joël et al.
2022In Biomedicines, 10 (12), p. 3066
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Keywords :
AAA; BM-573; ILT; abdominal aortic aneurysm; antagomir; antioxidant; antiplatelet therapy; inflammation; intraluminal thrombus; metformin; microRNAs; polyphenols; thromboxane A2; Medicine (miscellaneous); Biochemistry, Genetics and Molecular Biology (all); General Biochemistry, Genetics and Molecular Biology
Abstract :
[en] Pharmacotherapy for abdominal aortic aneurysm (AAA) can be useful for prevention, especially in people at higher risk, for slowing down AAA progression, as well as for post-surgery adjuvant treatment. Our review focuses on novel pharmacotherapy approaches targeted towards slowing down progression of AAA, known also as secondary prevention therapy. Guidelines for AAA are not specific to slow down the expansion rate of an abdominal aortic aneurysm, and therefore no medical therapy is recommended. New ideas are urgently needed to develop a novel medical therapy. We are hopeful that in the future, pharmacologic treatment will play a key role in the prevention and treatment of AAA.
Precision for document type :
Review article
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
MUSUMECI, Lucia  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique
Eilenberg, Wolf ;  Department of General Surgery, Division of Vascular Surgery, Medical University of Vienna, 1090 Vienna, Austria
Pincemail, Joël ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de chimie clinique
Yoshimura, Koichi;  Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan ; Graduate School of Health and Welfare, Yamaguchi Prefectural University, Yamaguchi 753-8502, Japan
Sakalihasan, Natzi  ;  Centre Hospitalier Universitaire de Liège - CHU > > Service de chirurgie cardio-vasculaire et thoracique
Language :
English
Title :
Towards Precritical Medical Therapy of the Abdominal Aortic Aneurysm.
Publication date :
29 November 2022
Journal title :
Biomedicines
eISSN :
2227-9059
Publisher :
MDPI, Switzerland
Volume :
10
Issue :
12
Pages :
3066
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 11 May 2023

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