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MUSUMECI Lucia

Département de chirurgie > Service de chirurgie cardio-vasculaire et thoracique

See author's contact details
ORCID
0000-0002-6942-5299
Main Referenced Co-authors
Oury, Cécile  (20)
Rahmouni, Souad  (17)
Lancellotti, Patrizio  (16)
Mustelin, Tomas (12)
Moutschen, Michel  (8)
Main Referenced Keywords
Humans (4); abdominal aortic aneurysm (3); cancer (2); LMPTP (2); platelets (2);
Main Referenced Unit & Research Centers
Biomolecular Science Center and Department of Molecular Biology and Microbiology, University of Central Florida (UCF), Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University (1)
Department of Orthopaedic Surgery and Institute for Genetic Medicine, University of Southern California Keck School of Medicine (1)
Dipartimento di Scienze Biomediche e Biotecnologie, Universita` degli Studi di Cagliari (1)
Division of Cellular Biology, Department of Molecular and Experimental Medicine, The Scripps Research Institute (1)
Fellowship for the Interpretation of Genomes, Center for Microbial Sciences, San Diego State University (1)
Main Referenced Disciplines
Cardiovascular & respiratory systems (12)
Immunology & infectious disease (9)
Biochemistry, biophysics & molecular biology (9)
Genetics & genetic processes (4)
Microbiology (4)

Publications (total 43)

The most downloaded
812 downloads
Musumeci, L., Arthur, J., Cheung, F., Hoque, A., Lippman, S., & Reichardt, J. (January 2010). Single nucleotide differences (SNDs) in the dbSNP database may lead to errors in genotyping and haplotyping studies. Human Mutation, 31 (1), 63-73. doi:10.1002/humu.21137 https://hdl.handle.net/2268/175667

The most cited

1389 citations (OpenAlex)

Bottini, N., Musumeci, L., Alonso, A., Rahmouni, S., Nika, K., Rostamkhani, M., MacMurray, J., Meloni, G. F., Lucarelli, P., Pellecchia, M., Eisenbarth, G. S., Comings, D., & Mustelin, T. (2004). A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nature Genetics, 36 (4), 337-8. doi:10.1038/ng1323 https://hdl.handle.net/2268/4854

Leeten, K., Jacques, N., Esquembre, L. A., Schneider, D. C., Straetener, J., Henriksen, C., MUSUMECI, L., Putters, F., Melo, S., Sánchez-López, E., Giera, M., Penoy, N., Piel, G., Verlaine, O., Amoroso, A., Joris, B., Slavetinsky, C. J., Goffin, E., Pirotte, B., ... Oury, C. (2024). Ticagrelor alters the membrane of Staphylococcus aureus and enhances the activity of vancomycin and daptomycin without eliciting cross-resistance. MBio, 0132224. doi:10.1128/mbio.01322-24
Peer Reviewed verified by ORBi

Praca, C., Sakalihasan, N., Defraigne, J.-O., Labropoulos, N., Albert, A., Seidel, L., & MUSUMECI, L. (17 June 2024). Endovascular Treatment of Abdominal Aortic Aneurysm: Impact of Diabetes on Endoleaks and Reintervention. Journal of Clinical Medicine, 13 (12), 3551. doi:10.3390/jcm13123551
Peer Reviewed verified by ORBi

Brüls, S., MUSUMECI, L., Courtois, A., Hustinx, R., SAKALIHASAN, S., Namur, G., Defraigne, J.-O., & Sakalihasan, N. (22 April 2024). Can Biomarkers and PET Imaging Predict Abdominal Aortic Aneurysm Growth Rate? Journal of Clinical Medicine, 13 (8), 2448. doi:10.3390/jcm13082448
Peer Reviewed verified by ORBi

Khbouz, B., MUSUMECI, L., Grahammer, F., & Jouret, F. (2024). The Dual-specificity Phosphatase 3 (DUSP3): A Potential Target Against Renal Ischemia/Reperfusion Injury. Transplantation. doi:10.1097/TP.0000000000005009
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Sakalihasan, N., Brüls, S., Hustinx, R., Tchana-Sato, V., SAKALIHASAN, S., Hultgren, R., Labropoulos, N., Colige, A., Durieux, R., Drion, P., Albert, A., Defraigne, J.-O., & MUSUMECI, L. (09 March 2024). Association between PET/CT Scan Findings, Treatment, and Cancer Incidence in a Cohort of AAA Patients. Journal of Clinical Medicine, 13 (6), 1569. doi:10.3390/jcm13061569
Peer Reviewed verified by ORBi

Pincemail, J.* , Tchana-Sato, V.* , Courtois, A., MUSUMECI, L., CHERAMY-BIEN, J.-P., Munten, J., Labropoulos, N., Defraigne, J.-O., & Sakalihasan, N. (16 May 2023). Alteration of Blood Oxidative Stress Status in Patients with Thoracic Aortic Dissection: A Pilot Study. Antioxidants, 12 (5), 1106. doi:10.3390/antiox12051106
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* These authors have contributed equally to this work.

Lancellotti, P., Aqil, A., MUSUMECI, L., Jacques, N., Ditkowski, B., Debuisson, M., Thiry, M., Dupont, J., Gougnard, A., Sandersen, C., CHERAMY-BIEN, J.-P., Sakalihasan, N., Nchimi Longang, A., Detrembleur, C., Jérôme, C., & Oury, C. (2023). Bioactive surface coating for preventing mechanical heart valve thrombosis. Journal of Thrombosis and Haemostasis. doi:10.1016/j.jtha.2023.05.004
Peer reviewed

Oury, C., Meyers, S., Jacques, N., Leeten, K., Jiang, Z., MUSUMECI, L., Lox, M., Debuisson, M., Goffin, E., Pirotte, B., Delvenne, P., Nchimi Longang, A., Hubert, C., Heptia, M., Hubert, P., Kuijpers, M. J. E., Vanassche, T., Martinod, K., Verhamme, P., & Lancellotti, P. (2023). Protective Effect of Ticagrelor Against Infective Endocarditis Induced by Virulent Staphylococcus aureus in Mice. JACC: Basic to Translational Science. doi:10.1016/j.jacbts.2023.02.003
Peer Reviewed verified by ORBi

MUSUMECI, L., Eilenberg, W., Pincemail, J., Yoshimura, K., & Sakalihasan, N. (29 November 2022). Towards Precritical Medical Therapy of the Abdominal Aortic Aneurysm. Biomedicines, 10 (12), 3066. doi:10.3390/biomedicines10123066
Peer Reviewed verified by ORBi

LANCELLOTTI, P., Oury, C., Pirotte, B., MUSUMECI, L., Jacques, N., & Goffin, E. (23 September 2021). Preparation of pyrimidine derivatives for prevention and treatment of Gram-negative bacterial infection, contamination and fouling.

Oury, C., Pirotte, B., MUSUMECI, L., Jacques, N., Goffin, E., & LANCELLOTTI, P. (22 October 2020). New pyrimidine derivatives for prevention and treatment of gram negative bacterial infection, contamination and fouling.

Musumeci, L., Oury, C., & Lancellotti, P. (2020). When your heart depends on your gut feelings. Revista Española de Cardiología (English Edition). doi:10.1016/j.rec.2020.03.006
Peer Reviewed verified by ORBi

Goffin, E., Jacques, N., Musumeci, L., Nchimi Longang, A., Oury, C., Lancellotti, P., & Pirotte, B. (2020). Synthesis of ticagrelor analogues belonging to 1,2,3-triazolo[4,5-d]pyrimidines and study of their antiplatelet and antibacterial activity. European Journal of Medicinal Chemistry, 208, 112767. doi:10.1016/j.ejmech.2020.112767
Peer Reviewed verified by ORBi

Lancellotti, P., Musumeci, L., & Oury, C. (2019). Are Antiplatelet Agents Beneficial in Prevention of Infective Endocarditis?-Reply. JAMA Cardiology. doi:10.1001/jamacardio.2019.3089
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Lancellotti, P., Musumeci, L., Jacques, N., Servais, L., Goffin, E., Pirotte, B., & Oury, C. (2019). Antibacterial Activity of Ticagrelor in Conventional Antiplatelet Dosages Against Antibiotic-Resistant Gram-Positive Bacteria. JAMA Cardiology. doi:10.1001/jamacardio.2019.1189
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Oury, C., Musumeci, L., Jacques, N., & LANCELLOTTI, P. (2019). Activité antibiotique de l'antiplaquettaire ticagrelor : une nouvelle piste contre l'antibiorésistance. Vaisseaux, Coeur, Poumons, 24 (7), 8-13.
Peer reviewed

Musumeci, L., Jacques, N., Hego, A., Nchimi Longang, A., Lancellotti, P., & Oury, C. (2018). Prosthetic Aortic Valves: Challenges and Solutions. Frontiers in Cardiovascular Medicine, 5, 46. doi:10.3389/fcvm.2018.00046
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Delierneux, C., Donis, N., Servais, L., Wéra, O., LECUT, C., Vandereyken, M., Musumeci, L., Rahmouni, S., Schneider, J., Eble, J., LANCELLOTTI, P., & Oury, C. (May 2017). Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides. Journal of Thrombosis and Haemostasis, 15 (5), 983-997. doi:10.1111/jth.13669
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Vandereyken, M., Singh, P., Wathieu, C., Jacques, S., Zurashvili, T., Dejager, L., Amand, M., Musumeci, L., Singh, M., MOUTSCHEN, M., Libert, C., & Rahmouni, S. (2017). Dual-Specificity Phosphatase Deletion Protects Female, but Not Male, Mice from Endotoxemia- and Polymicrobial-Induced Septic Shock. Journal of Immunology. doi:10.4049/jimmunol.1602092
Peer Reviewed verified by ORBi

Dubois, N., Willems, M., Kroonen, J., Berendsen, S., Van Hecke, W., Bredel, M., Musumeci, L., Poulet, C., Chakravarti, A., Bours, V., & Robe, P. (09 September 2016). Involvement of Ikbζ in glioblastomas and its potential implication in radioresistance [Poster presentation]. Annual Mini Symposium - EDT-Cancérologie Expérimentale, Bruxelles, Belgium.

Rahmouni, S., Hego, A., Delierneux, C., Wéra, O., Musumeci, L., Tautz, L., & Oury, C. (2016). Functional analysis of protein tyrosine phosphatases in thrombosis and haemostasis. In Protein Tyrosine Phosphatases: Methods and Protocols (pp. 301-30). New York, United States: Springer Science.
Peer reviewed

Dubois, N., Willems, M., Kroonen, J., Berendsen, S., Van Hecke, W., Bredel, M., Musumeci, L., Poulet, C., Chakravarti, A., Bours, V., & Robe, P. (2016). Involvement of Ikbζ in glioblastomas and its potential implication in radioresistance [Poster presentation]. 28th EORTC-NCI-AACR symposium on "Molecular targets and cancer therapeutics", Munich, Germany.

Willems, M., Dubois, N., Musumeci, L., Bours, V., & Robe, P. (2016). IkappaBzeta: an emerging player in cancer. Oncotarget, 7 (40), 66310-66322. doi:10.18632/oncotarget.11624
Peer Reviewed verified by ORBi

Rahmouni, S., MUSUMECI, L., Kuijpers, M. J., Gilio, K., Hego, A., Theatre, E., Senis, Y., Heemskerk, J., Thiry, M., Tautz, L., & Oury, C. (24 June 2015). DUSP3 Phosphatase Deficiency or Inhibition Limits Platelet Activation and Arterial Thrombosis [Paper presentation]. ISTH 2015 Congress, Toronto, Canada.

Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., MUSUMECI, L., Rahmouni, S., BOURS, V., Lancellotti, P., & Oury, C. (22 June 2015). CLEC-2 is required for the activation of mouse platelets by bacterial DNA mimetics [Paper presentation]. ISTH 2015 Congress, Toronto, Canada.

Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., MUSUMECI, L., Rahmouni, S., BOURS, V., LANCELLOTTI, P., & Oury, C. (22 June 2015). CLEC-2 is required for the activation of mouseplatelets by bacterial DNA mimetics [Paper presentation]. ISTH 2015 Congress, Toronto, Canada.

Singh, P.* , Dejager, L.* , Amand, M.* , Theatre, E., Vandereyken, M., Zurashvili, T., Singh, M., Mack, M., Timmermans, S., Musumeci, L., Dejardin, E., Mustelin, T., Van Ginderachter, J. A., Moutschen, M., Oury, C., Libert, C.* , & Rahmouni, S.*. (15 May 2015). DUSP3 genetic deletion confers M2-like−macrophage-dependent tolerance to septic shock. Journal of Immunology, 194 (10), 4951-62. doi:10.4049/jimmunol.1402431
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Musumeci, L., Kuijpers, M., Gilio, K., Hego, A., Theatre, E., Maurissen, L., Vandereyken, M., Diogo, C., LECUT, C., Guilmain, W., Bobkova, E., Eble, J., Dahl, R., Drion, P., Rascon, J., Mostofi, Y., Yuan, H., Sergienko, E., Chung, T., ... Rahmouni, S.*. (17 February 2015). DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis. Circulation, 131 (7), 656-68. doi:10.1161/CIRCULATIONAHA.114.010186
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., Musumeci, L., Rahmouni, S., Thiry, M., Compère, P., BOURS, V., Lancellotti, P., & Oury, C. (27 January 2015). Bacterial DNA mimetics activate platelets and promote thrombosis via CLEC-2 [Poster presentation]. GIGA-DAY: Current advances in medical genetics and genomics, Liège, Belgium.

Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., MARTIN, M., Dequiedt, F., Drion, P., Singh, P., Vandereyken, M., Musumeci, L., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (27 January 2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase [Poster presentation]. GIGA Day 2014, Liège, Belgium.

Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., Martin, M., Dequiedt, F., Drion, P., Singh, P., Zurashvili, T., Vandereyken, M., Musumeci, L., Mustelin, T., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Molecular Cancer. doi:10.1186/1476-4598-13-108
Peer Reviewed verified by ORBi

Musumeci, L., Maurissen, L., Kuijpers, M. J., Senis, Y., MOUTSCHEN, M., Mustelin, T., Heemskerk, J. W., Oury, C., & Rahmouni, S. (02 July 2013). Genetic deletion of Vaccinia H1-related (VHR) phosphatase inhibits collagen-induced platelet activation and thrombus formation without affecting bleeding time in mice [Paper presentation]. XXIVth Congress of the ISTH, Amsterdam, Netherlands.

Rahmouni, S., Singh, P., Dejager, L., Singh, M., Amand, M., Musumeci, L., Moutschen, M., Mustelin, T., & Libert, C. (2013). Dual-specificity phosphatase 3 knockout female mice are resistant to LPS and to polymicrobial induced septic shock in TNF dependent manner. Journal of Immunology.
Peer Reviewed verified by ORBi

Tautz, L., Vang, T., Liu, W., Delacroix, L., Wu, S., Vasile, S., Dahl, R., Yang, L., MUSUMECI, L., Francis, D., Landskron, J., Tasken, K., Tremblay, M., Lie, B., Page, R., Mustelin, T., Rahmouni, S., & Rickert, R. (April 2012). Dynamic interaction between lymphoid tyrosine phosphatase and C-terminal Src kinase controls T cell activation. FASEB Journal, 26.
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Vang, Liu, W. H., Delacroix, L., Wu, S., Vasile, S., Dahl, R., Yang, L., Musumeci, L., Francis, D., Landskron, J., Tasken, T., Tremblay, M. L., Lie, B. A., Page, R., Mustelin, T., Rahmouni, S., Rickert, R. C., & Tautz, L. (2012). LYP inhibits T-cell activation when dissociated from CSK. Nature Chemical Biology. doi:10.1038/nchembio.916
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Singh, M., Singh, P., Gaudray, G., Musumeci, L., Thielen, C., VAIRA, D., Vandergeeten, C., Delacroix, L., Van Gulck, E., Vanham, G., de Leval, L., Rahmouni, S., & MOUTSCHEN, M. (2012). An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses. PLoS ONE, 7 (6), 38491. doi:10.1371/journal.pone.0038491
Peer Reviewed verified by ORBi

Musumeci, L., Arthur, J., Cheung, F., Hoque, A., Lippman, S., & Reichardt, J. (January 2010). Single nucleotide differences (SNDs) in the dbSNP database may lead to errors in genotyping and haplotyping studies. Human Mutation, 31 (1), 63-73. doi:10.1002/humu.21137
Peer Reviewed verified by ORBi

Musumeci, L., Bongiorni, C., Tautz, L., Edwards, R., Osterman, A., Perego, M., Mustelin, T., & Bottini, N. (July 2005). Low-Molecular-Weight Protein Tyrosine Phosphatases of Bacillus subtilis. Journal of Bacteriology, 187 (14), 4945-4956. doi:10.1128/JB.187.14.4945-4956.2005
Peer Reviewed verified by ORBi

Mijakovic, I., Musumeci, L., Tautz, L., Petranovic, D., Edwards, R., Jensen, P. R., Mustelin, T., Deutscher, J., & Bottini, N. (May 2005). In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE. Journal of Bacteriology, 187 (10), 3384-90. doi:10.1128/JB.187.10.3384-3390.2005
Peer Reviewed verified by ORBi

Vang, T., Congia, M., Macis, M. D., Musumeci, L., Orru, V., Zavattari, P., Nika, K., Tautz, L., Tasken, K., Cucca, F., Mustelin, T., & Bottini, N. (2005). Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nature Genetics, 37 (12), 1317-9. doi:10.1038/ng1673
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Bottini, N., Musumeci, L., Alonso, A., Rahmouni, S., Nika, K., Rostamkhani, M., MacMurray, J., Meloni, G. F., Lucarelli, P., Pellecchia, M., Eisenbarth, G. S., Comings, D., & Mustelin, T. (2004). A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nature Genetics, 36 (4), 337-8. doi:10.1038/ng1323
Peer Reviewed verified by ORBi

Huynh, H., Bottini, N., Williams, S., Cherepanov, V., Musumeci, L., Saito, K., Bruckner, S., Vachon, E., Wang, X., Kruger, J., Chow, C.-W., Pellecchia, M., Monosov, E., Greer, P. A., Trimble, W., Downey, G. P., & Mustelin, T. (2004). Control of vesicle fusion by a tyrosine phosphatase. Nature Cell Biology, 6 (9), 831-9. doi:10.1038/ncb1164
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Junqueira, D.* , Cilenti, L.* , Musumeci, L., Sedivy, J., & Zervos, A. (January 2003). Random mutagenesis of PDZOmi domain and selection of mutants that specifically bind the Myc proto-oncogene and induce apoptosis. Oncogene, 22, 2772–2781. doi:10.1038/sj.onc.1206359
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

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