[en] Background: Literature about the lung microbiota (LM) in dogs is sparse. Influence of breed and living conditions
on the LM in healthy dogs is currently unknown, as well as the influence of chronic respiratory diseases such as
canine idiopathic pulmonary fibrosis (CIPF) in West highland white terriers (WHWTs). Aims of this study were (1) to
assess the characteristics of the healthy LM according to breed and living conditions, and (2) to study LM changes
associated with CIPF in WHWTs. Forty-five healthy dogs divided into 5 groups: domestic terriers (n = 10), domestic
shepherds (n = 11), domestic brachycephalic dogs (n = 9), domestic WHWTs (n = 6) (H-WHWTs) and experimental
beagles (n = 9) and 11 diseased WHWTs affected with CIPF (D-WHWTs) were included in the study to achieve those
objectives.
Results: In healthy domestic dogs, except in H-WHWTs, the presence of few discriminant genera in each type of
breed was the only LM modification. LM of experimental dogs displayed a change in b-diversity and an increased
richness compared with domestic dogs. Moreover, Prevotella_7 and Dubosiella genera were more abundant and 19
genera were discriminant in experimental dogs. LM of both H-WHWTs and D-WHWTs revealed increased abundance of
6 genera (Brochothrix, Curvibacter, Pseudarcicella, Flavobacteriaceae genus, Rhodoluna and Limnohabitans) compared
with other healthy domestic dogs. Brochothrix and Pseudarcicella were also discriminant in D-WHWTs compared with
H-WHWTs and other healthy domestic dogs.
Conclusions: In domestic conditions, except for H-WHWT, the breed appears to have minor influence on the LM. LM
modifications were found in experimental compared with domestic living conditions. LM modifications in H-WHWTs
and D-WHWTs compared with other healthy domestic dogs were similar and seemed to be linked to the breed.
Whether this breed difference might be related with the high susceptibility of WHWTs for CIPF requires further studies.
Disciplines :
Veterinary medicine & animal health Microbiology
Author, co-author :
Fastrès, Aline ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Médecine interne des animaux de compagnie
Roels, Elodie ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Pathologie médicale des petits animaux
Vangrinsven, Emilie ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Pathologie médicale des petits animaux
Taminiau, Bernard ; Université de Liège - ULiège > Département de sciences des denrées alimentaires (DDA) > Microbiologie des denrées alimentaires
Jabri, Hiba ; Université de Liège - ULiège > Département de sciences des denrées alimentaires (DDA) > Microbiologie des denrées alimentaires
Bolen, Géraldine ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Imagerie médicale
Merveille, Anne-Christine ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Pathologie médicale des petits animaux
Tutunaru, Alexandru-Cosmin ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Anesthésiologie gén. et pathologie chirurg. des grds animaux
Moyse, Evelyne ; Université de Liège - ULiège > Dpt. de gestion vétérinaire des Ressources Animales (DRA) > Biostatistiques et bioinformatique appliquées aux sc. vétér.
Daube, Georges ; Université de Liège - ULiège > Département de sciences des denrées alimentaires (DDA) > Microbiologie des denrées alimentaires
Clercx, Cécile ; Université de Liège - ULiège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Pathologie médicale des petits animaux
Language :
English
Title :
Assessment of the lung microbiota in dogs: influence of the type of breed, living conditions and canine idiopathic pulmonary fibrosis
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