[en] The fast pace of changes occurring in the pharmaceutical world emphasizes the need for powerful technologies that allow checking the quality of pharmaceutical products. Infrared and Raman spectroscopies have shown great potentialities for drug analysis in the last decades and consequently caught the attention of the scientific world as well as of industrial developers, leading to major technological advancements. These fast, eco-friendly, and non-destructive techniques help gather essential information about the samples under examination with consistent advantages. This review focuses on the application of portable/handheld NIR and Raman spectrophotometers in the analysis of pharmaceutical products for both in-process and quality control tests. Moreover, several analytical methods developed by several authors are described in order to illustrate the applications explored until now.
Research center :
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Deidda, Riccardo ✱; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Sacre, Pierre-Yves ✱; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Clavaud, Matthieu
Coic, Laureen ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Avohou, Tonakpon Hermane ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Hubert, Philippe ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
Ziemons, Eric ; Université de Liège - ULiège > Département de pharmacie > Chimie analytique
✱ These authors have contributed equally to this work.
Language :
English
Title :
Vibrational spectroscopy in analysis of pharmaceuticals: Critical review of innovative portable and handheld NIR and Raman spectrophotometers
Publication date :
May 2019
Journal title :
TrAC: Trends in Analytical Chemistry
ISSN :
0165-9936
eISSN :
1879-3142
Publisher :
Elsevier, Amsterdam, Netherlands
Volume :
114
Pages :
251-259
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
DGTRE - Région wallonne. Direction générale des Technologies, de la Recherche et de l'Énergie [BE] FEDER - Fonds Européen de Développement Régional [BE]
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