Profil

Ziemons Eric

Département de pharmacie > Chimie analytique

Département de pharmacie

CIRM

See author's contact details
ORCID
0000-0001-6117-2031

Main Research Fields
Pharmacy, pharmacology & toxicology
Chemistry
Mathematics
Physical, chemical, mathematical & earth Sciences: Multidisciplinary, general & others
Laboratory medicine & medical technology
Main Keywords
Validation; Raman spectroscopy; Near infrared spectroscopy; Process Analytical Technology; Spectroscopie proche infrarouge;
Main Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège
Centre Interfacultaire de Recherche du Médicament - CIRM
C.I.R.M.
Laboratoire de chimie analytique
C.I.R.M
Main Co-authors
Hubert, Philippe 
Sacre, Pierre-Yves 
De Bleye, Charlotte 
Rozet, Eric 
Marini Djang'Eing'A, Roland 

Publications (total 391)

The most downloaded
2250 downloads
Chavez, P.-F., De Bleye, C., Sacre, P.-Y., Rozet, E., Hubert, P., & Ziemons, E. (February 2013). Validation methodologies of near infrared spectroscopy methods in pharmaceutical applications. European Pharmaceutical Review, 18 (1), 3-6. https://hdl.handle.net/2268/143602
The most cited
216 citations (SCOPUS)
Rozet, E., Ceccato, A., Hubert, C., Ziemons, E., Oprean, R., Rudaz, S., Boulanger, B., & Hubert, P. (2007). Analysis of recent pharmaceutical regulatory documents on analytical method validation. Journal of Chromatography. A, 1158 (1-2), 111-25. doi:10.1016/j.chroma.2007.03.111 https://hdl.handle.net/2268/3646

Elderderi, S., Sacre, P.-Y., Wils, L., Chourpa, I., Elbashir, A. A., Hubert, P., Byrne, H. J., Boudesocque-Delaye, L., Ziemons, E., & Bonnier, F. (27 July 2022). Comparison of Vibrational Spectroscopic Techniques for Quantification of Water in Natural Deep Eutectic Solvents. Molecules, 27 (15), 4819. doi:10.3390/molecules27154819
Peer Reviewed verified by ORBi

Hamla, S., Sacre, P.-Y., Derenne, A., Cowper, B., Goormaghtigh, E., Hubert, P., & Ziemons, E. (09 July 2022). A New Alternative Tool to Analyse Glycosylation in Monoclonal Antibodies Based on Drop-Coating Deposition Raman imaging: A Proof of Concept. Molecules, 27 (14), 4405. doi:10.3390/molecules27144405
Peer Reviewed verified by ORBi

Ciza Hamuli, P., Sacre, P.-Y., Waffo Tchounga, C. A., Kimbeni, T. M., Masereel, B., Hubert, P., Ziemons, E., & Marini Djang'Eing'A, R. (July 2022). Comparison of several strategies for the deployment of a multivariate regression model on several handheld NIR instruments. Application to the quality control of medicines. Journal of Pharmaceutical and Biomedical Analysis, 215, 114755. doi:10.1016/j.jpba.2022.114755
Peer Reviewed verified by ORBi

Bielfeldt, S.* , Bonnier, F.* , Byrne, H. J.* , Chourpa, I.* , Dancik, Y.* , Lane, M. E.* , Lunter, D. J.* , Munnier, E.* , Puppels, G.* , Tfayli, A.* , & Ziemons, E.*. (14 June 2022). Monitoring dermal penetration and permeation kinetics of topical products; the role of Raman microspectroscopy. TrAC: Trends in Analytical Chemistry, 156, 116709. doi:10.1016/j.trac.2022.116709
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Waffo Tchounga, C. A.* , Sacre, P.-Y., Ciza Hamuli, P., Ngono Rose, Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R.*. (07 June 2022). DD-SIMCA and PLS regression models applied to NIR spectroscopy for identification and assay of ciprofloxacin tablets. Paper presented at Congrès de Chimiométrie 2022, Brest, France.
Peer reviewed

Hamla, S., Sacre, P.-Y., Derenne, A., Derfoufi, K.-M., Cowper, B., I. Butré, C., Delobel, A., Goormaghtigh, E., Hubert, P., & Ziemons, E. (07 June 2022). Is SVM a black box? Visualization and interpretation of SVR models to analyze glycosylation in pharmaceutical proteins (mAbs, Fc) based on infrared spectroscopy FT-IR. Poster session presented at Congrès CHIMIOMETRIE, Brest, France.
Peer reviewed

De Bleye, C., Lebrun, P., Sacre, P.-Y., Laurent, A., Kemik, K., Hubert, C., Hubert, P., & Ziemons, E. (20 May 2022). Optimisation robuste de la synthèse de nanoparticules d’argent en vue de leur utilisation en spectroscopie Raman exaltée de surface. Paper presented at GFSV 2022, Nivelles, Belgium.

Hamla, S., Sacre, P.-Y., Derenne, A., Goormaghtigh, E., Hubert, P., & Ziemons, E. (18 May 2022). Identification of monoclonal antibodies based on Drop-Coating Deposition Raman imaging (DCDR) combined with Multivariate Curve Resolution Alternating Least Square (MCR-ALS) analysis. Poster session presented at Journées du Groupe Français de Spectroscopie Vibrationnelle, Nivelles, Belgium.
Peer reviewed

Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (2022). Applications de la spectroscopie vibrationnelle pour le contrôle qualité des médicaments de qualité inférieure et falsifiés. Paper presented at Cours sur la falsification des médicaments, Paris, France.

Avohou, T. H.* , Sacre, P.-Y., Hubert, P., & Ziemons, E. (04 March 2022). Interpretable One-Class Classification of Raman Spectra Using Prediction Bands Estimated by Wavelet Regression. Analytical Chemistry, 94, 4183-4191. doi:10.1021/acs.analchem.1c04098
Peer Reviewed verified by ORBi

Coic, L., Sacre, P.-Y., Dispas, A., De Bleye, C., Fillet, M., Ruckebusch, C., Hubert, P., & Ziemons, E. (March 2022). Selection of essential spectra to improve the multivariate curve resolution of minor compounds in complex pharmaceutical formulations. Analytica Chimica Acta, 1198, 339532. doi:10.1016/j.aca.2022.339532
Peer Reviewed verified by ORBi

Hamla, S., Sacre, P.-Y., Derenne, A., Derfoufi, K.-M., Cowper, B., Butré, C. I., Delobel, A., Goormaghtigh, E., Hubert, P., & Ziemons, E. (2022). A new alternative tool to analyse glycosylation in pharmaceutical proteins based on infrared spectroscopy combined with nonlinear support vector regression. Analyst. doi:10.1039/D1AN00697E
Peer Reviewed verified by ORBi

Sacre, P.-Y., Waffo Tchounga, C. A., Ciza Hamuli, P., Avohou, T. H., De Bleye, C., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (02 February 2022). Applications of vibrational spectroscopy and imaging for the analysis of substandard or falsified medicines. Paper presented at CIRM DAY.

Horne, J., De Bleye, C., Laurent, A., Kemik, K., Hubert, C., Hubert, P., & Ziemons, E. (02 February 2022). COMBINING CHARACTERIZATION TOOLS FOR SCREENING OF CRITICAL PARAMETERS LEADING TO REPRODUCIBLE SYNTHESIS OF SILVER NANOPARTICLES. Paper presented at CIRMday 2022, Liege, Belgium.

Kagheni Mbayahi, E., Kitasuvirwa, W., Ciza Hamuli, P., Waffo Tchounga, C. A., Hubert, P., Sacre, P.-Y., Ziemons, E., Kalonji, N. J.-B., & Marini Djang'Eing'A, R. (02 February 2022). Quality control of anti-infective medicines : case of ciprofloxacin and metronidazole formulations in Butembo. Poster session presented at CIRM Day 2022, Liège, Belgium.

Sacre, P.-Y., Alaoui Mansouri, M., De Bleye, C., Coic, L., Hubert, P., & Ziemons, E. (25 January 2022). Evaluation of distributional homogeneity of pharmaceutical formulation using laser direct infrared imaging. International Journal of Pharmaceutics, 612 (121373). doi:10.1016/j.ijpharm.2021.121373
Peer Reviewed verified by ORBi

Koch, N., Jennotte, O., Ziemons, E., Boussard, G., Lechanteur, A., & Evrard, B. (2022). Influence of API physico-chemical properties on amorphization capacity of several mesoporous silica loading methods. International Journal of Pharmaceutics. doi:10.1016/j.ijpharm.2021.121372
Peer Reviewed verified by ORBi

Deidda, R., Dispas, A., De Bleye, C., Hubert, P., & Ziemons, E. (2022). Critical review on recent trends in cannabinoid determination on cannabis herbal samples: From chromatographic to vibrational spectroscopic techniques. Analytica Chimica Acta, 1209, 339184. doi:10.1016/j.aca.2021.339184
Peer Reviewed verified by ORBi

Jambo, H., Dispas, A., Hubert, C., Lecomte, F., Ziemons, E., & Hubert, P. (2022). Generic SFC-MS methodology for the quality control of vitamin D3 oily formulations. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2021.114492
Peer Reviewed verified by ORBi

Sacre, P.-Y., De Bleye, C., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (2022). Interest of Raman spectroscopy for the detection and analysis of poor-quality medicines. Paper presented at 9th International Conference on Advanced Applied Raman Spectroscopy (RamanFest2022), Paris, France.
Editorial reviewed

Coic, L., Sacre, P.-Y., De Bleye, C., Hubert, P., & Ziemons, E. (25 November 2021). La microscopie moyen infrarouge: Théorie et applications dans le domaine pharmaceutique et biomédical. Paper presented at Journées GFSV 2021: Imagerie et Spectroscopie Vibrationnelle.

Waffo Tchounga, C. A., Sacre, P.-Y., Ciza Hamuli, P., Ziemons, E., Hubert, P., Ngono Mballa, R., & Marini Djang'Eing'A, R. (05 October 2021). Development and validation of an LC-UV method for the simultaneous analyses of ciprofloxacin and metronidazole in tablet dosage forms: routine application and confirmation of falsifications. Poster session presented at Congrès de Sciences Séparatives, Paris, France.

Emonts, P., Avohou, T. H., Hubert, P., Ziemons, E., Fillet, M., & Dispas, A. (October 2021). Development of a sensitive MEKC-LIF method for the analysis of synthetic cathinones and amphetamines Paul Emonts. Poster session presented at SEP2021, Paris, France.

Emonts, P., Avohou, T. H., Hubert, P., Ziemons, E., Fillet, M., & Dispas, A. (October 2021). Optimization of a robust and reliable FITC labeling process for CE-LIF analysis of pharmaceutical compounds using design of experiments strategy. Journal of Pharmaceutical and Biomedical Analysis, 205, 114304. doi:10.1016/j.jpba.2021.114304
Peer Reviewed verified by ORBi

Deidda, R., Avohou, T. H., Dumont, E., Hubert, C., Hubert, P., De Bleye, C., & Ziemons, E. (2021). Application of the analytical quality by design principles to the development of a qualitative surface-enhanced Raman scattering method: A proof of concept. Journal of Raman Spectroscopy. doi:10.1002/jrs.6249
Peer Reviewed verified by ORBi

Ciza Hamuli, P., Sacre, P.-Y., Kanyonyo, M. R., Waffo Tchounga, C. A., Borive, M. A., Coic, L., Mbinze, J., Hubert, P., Ziemons, E., & Marini Djang'Eing'A, R. (August 2021). Application of NIR handheld transmission spectroscopy and chemometrics to assess the quality of locally produced antimalarial medicines in the Democratic Republic of Congo. Talanta Open, 3, 100025. doi:10.1016/j.talo.2020.100025
Peer Reviewed verified by ORBi

Kasemiire, A., Avohou, T. H., De Bleye, C., Sacre, P.-Y., Dumont, E., Hubert, P., & Ziemons, E. (11 June 2021). Design of experiments and design space approaches in the pharmaceutical bioprocess optimization. European Journal of Pharmaceutics and Biopharmaceutics, 166 (September), 144-154. doi:10.1016/j.ejpb.2021.06.004
Peer Reviewed verified by ORBi

Sacre, P.-Y., De Bleye, C., Hubert, P., & Ziemons, E. (2021). PAT Applications of NIR Spectroscopy in the Pharmaceutical Industry. In R. A. Crocombe, P. E. Leary, & B. W. Kammrath (Eds.), Portable Spectroscopy and Spectrometry, Volume 1, Technologies and Instrumentation (pp. 67-82). Wiley.
Peer reviewed

Waffo Tchounga, C. A., Sacre, P.-Y., Ciza Hamuli, P., Ngono Mballa, R., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (19 May 2021). Determination of the composition of falsified chloroquine phosphate samples seized in Cameroon, DRC and Niger during covid-19 pandemic. Paper presented at CIRM DAY, Liège, Belgium.

Deidda, R.* , Coppey, F.* , Damergi, D., Schelling, C., Coic, L., Veuthey, J.-L., Sacre, P.-Y., De Bleye, C., Hubert, P., Esseiva, P., & Ziemons, E. (2021). New perspective for the in-field analysis of cannabis samples using handheld near-infrared spectroscopy: A case study focusing on the determination of Δ9-tetrahydrocannabinol. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2021.114150
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Coic, L., Sacre, P.-Y., Dispas, A., De Bleye, C., Fillet, M., Ruckebusch, C., Hubert, P., & Ziemons, E. (22 April 2021). Pixel-based Raman hyperspectral identification of complex pharmaceutical formulations. Analytica Chimica Acta, 1155, 338361. doi:10.1016/j.aca.2021.338361
Peer Reviewed verified by ORBi

Dumont, E., De Bleye, C., Rademaker, G., Coic, L., Horne, J., Sacre, P.-Y., Peulen, O., Hubert, P., & Ziemons, E. (01 March 2021). Development of a prototype device for near real-time surface-enhanced Raman scattering monitoring of biological samples. Talanta, 224, 121866. doi:10.1016/j.talanta.2020.121866
Peer Reviewed verified by ORBi

Sounouvou, A. G. H. T., Defourny, C., Gbaguidi, F., Ziemons, E., Piel, G., Quetin-Leclercq, J., & Evrard, B. (01 March 2021). Development of a highly persistent silicone-based sprayable emulsion containing essential oils for treatment of skin infections. International Journal of Pharmaceutics, 596. doi:10.1016/j.ijpharm.2021.120214
Peer Reviewed verified by ORBi

Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (03 February 2021). Using prediction bands for near-infrared spectra for authentication and verification of drug products. Paper presented at eChimiométrie 2021.

Avohou, T. H., Sacre, P.-Y., Lebrun, P., Hubert, P., & Ziemons, E. (01 February 2021). A probabilistic class-modelling method based on prediction bands for functional spectral data: Methodological approach and application to near-infrared spectroscopy. Analytica Chimica Acta, 1144, 130-149. doi:10.1016/j.aca.2020.11.039
Peer Reviewed verified by ORBi

Coic, L., Sacre, P.-Y., Dispas, A., De Bleye, C., Fillet, M., Ruckebusch, C., Hubert, P., & Ziemons, E. (February 2021). Pixel-based identification of Raman hyperspectral data: application to pharmaceutical tablets impurities detection. Paper presented at e-Chimiométrie 2021.

Alaoui Mansouri, M., Ziemons, E., Sacre, P.-Y., kharbach, M., Barra, I., Cherrah, Y., Hubert, P., Marini Djang'Eing'A, R., & Bouklouze, A. (26 January 2021). Classification of polymorphic forms of fluconazole in pharmaceuticals by FT-IR and FT-NIR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 196, 113022. doi:10.1016/j.jpba.2021.113922
Peer Reviewed verified by ORBi

Emonts, P., Servais, A.-C., Ziemons, E., Hubert, P., Fillet, M., & Dispas, A. (January 2021). Development of a sensitive MEKC‐LIF method for synthetic cathinones analysis. Electrophoresis, 0, 1-8. doi:10.1002/elps.202000331
Peer Reviewed verified by ORBi

Deidda, R., Schelling, C., Roussel, J.-M., Dispas, A., De Bleye, C., Ziemons, E., Hubert, P., & Veuthey, J.-L. (2020). The analysis of cannabinoids in cannabis samples bysupercritical fluid chromatography and ultra-high-performanceliquid chromatography: A comparison study. Analytical Science Advances, 1-13. doi:10.1002/ansa.202000091
Peer Reviewed verified by ORBi

Waffo Tchounga, C. A., Sacre, P.-Y., Ciza Hamuli, P., NGONO Mballa, R., Ziemons, E., HUBERT, P., & Marini Djang'Eing'A, R. (12 November 2020). Composition analysis of falsified chloroquine phosphate samples seized during the COVID-19 pandemic. Journal of Pharmaceutical and Biomedical Analysis, 194, 113761. doi:10.1016/j.jpba.2020.113761
Peer Reviewed verified by ORBi

Hamla, S., Derenne, A., Derfoufi, K.-M., Sacre, P.-Y., Hubert, P., Ziemons, E., & Goormaghtigh, E. (27 October 2020). A new convenient tool to analyse protein glycosylation based on FT-IR spectroscopy. Paper presented at GSK MEETS BELGIAN UNIVERSITIES EVENT, Brussels, Belgium.

Coppey, F., Bécue, A., Sacre, P.-Y., Ziemons, E., Hubert, P., & Esseiva, P. (10 September 2020). Providing illicit drugs results in five seconds using ultra-portable NIR technology: An opportunity for forensic laboratories to cope with the trend toward the decentralization of forensic capabilities. Forensic Science International, 317, 110498. doi:10.1016/j.forsciint.2020.110498
Peer Reviewed verified by ORBi

Coic, L., Sacre, P.-Y., Dispas, A., Dumont, E., Horne, J., De Bleye, C., Fillet, M., Hubert, P., & Ziemons, E. (01 July 2020). Evaluation of the analytical performances of two Raman handheld spectrophotometers for pharmaceutical solid dosage form quantitation. Talanta, 214, 120888. doi:10.1016/j.talanta.2020.120888
Peer Reviewed verified by ORBi

Dumont, E., De Bleye, C., Haouchine, M., Coic, L., Sacre, P.-Y., Hubert, P., & Ziemons, E. (05 June 2020). Effect of the functionalisation agent on the surface-enhanced Raman scattering (SERS) spectrum: Case study of pyridine derivatives. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 233, 118180. doi:10.1016/j.saa.2020.118180
Peer Reviewed verified by ORBi

De Bleye, C., Fontaine, M., Dumont, E., Sacre, P.-Y., Hubert, P., Theys, N., & Ziemons, E. (15 April 2020). Raman imaging as a new analytical tool for the quality control of the monitoring of osteogenic differentiation in forming 3D bone tissue. Journal of Pharmaceutical and Biomedical Analysis, 186, 113319. doi:10.1016/j.jpba.2020.113319
Peer Reviewed verified by ORBi

Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (18 February 2020). A one-class Classification method based on depth statistics : applications to process analytical technology (PAT) and detection of counterfeited drugs. Paper presented at Weekly CIRM Scientific Seminar, Liege, Belgium.

Ciza Hamuli, P., Sacre, P.-Y., Kanyonyo, M., Waffo Tchounga, C. A., Coic, L., mbinze, J., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (28 January 2020). Application of vibrationnal spectroscopy and chemometrics to access the quality of Locally produced antimalarial medicines in the Democratic Republic of Congo. Poster session presented at Conférence Chimiométrie 2020, ULiège - Université de Liège, Belgium.

Emonds-Alt, G., Avohou, T. H., Kasemiire, A., Malherbe, C., Monbaliu, J.-C., Ziemons, E., & Eppe, G. (28 January 2020). In-line monitoring of glyphosate in a microfluidic setup by SERS, development and optimization by DoE. Poster session presented at Chimiométrie XXI, Liège, Belgium.

Deidda, R., Damergi, D., Coppey, F., De Bleye, C., Coic, L., Sacre, P.-Y., Hubert, P., Ziemons, E., Esseiva, P., & Veuthey, J.-L. (28 January 2020). Handheld Near Infrared spectroscopy for cannabis analysis: from the analytical problem to the chemometric solution. Paper presented at Chimiométrie 2020, Liège, Belgium.

Deidda, R., El Morabit, L., De Bleye, C., Sacre, P.-Y., Boccard, J., Hubert, P., Ziemons, E., Vernaz, N., Tobolkina, E., Veuthey, J.-L., & Rudaz, S. (28 January 2020). Near infrared spectroscopy as a screening technique for the quality control of antiretroviral drugs for HIV treatment in Swiss prisons. Poster session presented at Chimiométrie 2020, Liège, Belgium.

Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (28 January 2020). A probabilistic class-modelling method based on Bayesian prediction intervals for functional depth (vs outlyingness) statistics. Paper presented at Chimiométrie 2020, Liège, Belgium.

Hamla, S., Sacre, P.-Y., Derenne, A., Goormaghtigh, E., Hubert, P., & Ziemons, E. (28 January 2020). Partial least squares (PLS) vs support vector machine (SVM) vs artificial neural network (ANN). Which model is the best performer in predicting monosaccharide content of pharmaceutical proteins based on their FT-IR spectrum? Poster session presented at Conférence Chimiométrie 2020, Liège, Belgium.

Cailletaud, J., De Bleye, C., Dumont, E., Sacre, P.-Y., Gut, Y., Leblanc, N., Letellier, P., Ginot, Y.-M., Hubert, P., & Ziemons, E. (25 January 2020). Detection of low dose of piroxicam polymorph in pharmaceutical tablets by surface-enhanced Raman chemical imaging (SER-CI) and multivariate analysis. International Journal of Pharmaceutics, 574, 118913. doi:10.1016/j.ijpharm.2019.118913
Peer Reviewed verified by ORBi

Alaoui Mansouri, M., Sacre, P.-Y., Coic, L., De Bleye, C., Dumont, E., Bouklouze, A., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (15 January 2020). Quantitation of Active Pharmaceutical Ingredient through the Packaging Using Raman Handheld Spectrophotometers: A Comparison Study. Talanta, 207, 120306. doi:10.1016/j.talanta.2019.120306
Peer Reviewed verified by ORBi

Coic, L., Sacre, P.-Y., Dispas, A., Dumont, E., De Bleye, C., Fillet, M., Hubert, P., & Ziemons, E. (January 2020). How to analyse big data in hyperspectral imaging? Application for the elucidation of medicine composition. Poster session presented at Chimiométrie 2020, Liège, Belgium.

Dispas, A., Emonts, P., Avohou, T. H., Ziemons, E., Hubert, P., & Fillet, M. (January 2020). Design of experiments approach to optimize FITC labeling process. Poster session presented at Chimiométrie 2020, Liège, Belgium.

Coic, L., Sacre, P.-Y., Dispas, A., Dumont, E., De Bleye, C., Fillet, M., Hubert, P., & Ziemons, E. (11 December 2019). Which tools can help to thwart “out of memory” issues during analysis of big data? Poster session presented at CIRM Day 2nd edition.

Hamla, S., Sacre, P.-Y., Derenne, A., Goormaghtigh, E., Hubert, P., & Ziemons, E. (11 December 2019). COMPARISON OF THE QUANTITATIVE PERFORMANCES OF FT-IR SPECTROSCOPY IN PREDICTING MONOSACCHARIDES CONTENT OF PHARMACEUTICAL PROTEINS USING PARTIAL LEAST SQUARES (PLS) AND SUPPORT VECTOR MACHINE (SVM) REGRESSION MODELS. Poster session presented at sabrina HAMLA, Liège, Belgium.

Dumont, E., De Bleye, C., Coic, L., Sacre, P.-Y., Hubert, P., & Ziemons, E. (11 December 2019). How to overcome the protein corona problem in surface-enhanced Raman scattering (SERS) analyses of cell culture media. Paper presented at 2nd CIRM Scientific Day, Liège, Belgium.

Dumont, E., De Bleye, C., Cailletaud, J., Coic, L., Sacre, P.-Y., Hubert, P., & Ziemons, E. (29 November 2019). A new way of overcoming the protein corona problem in surface-enhanced Raman scattering (SERS): the use of membrane filters. Poster session presented at Bioforum of BioLiege 2019, Liège, Belgium.

Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (2019). Concept and prototype V4F for classification. Paper presented at Meeting for transfer of knowledge to Biion & Pharmalex, V4F, Mont Saint-Guilbert, Belgium.

Avohou, T. H., Sacre, P.-Y., Lebrun, P., Hubert, P., & Ziemons, E. (15 November 2019). Class-modelling methods based on 𝜷-expectation tolerance regions for functional spectral (NIR and Raman) data. Paper presented at Scientific Workshops, Pharmalex, Mont Sain-Guilbert, Belgium.

Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (24 October 2019). Spectrophotomètres portables :l’analyse chimique à portée de tous? Paper presented at Liège Créative, Liege, Belgium.

Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (2019). Logiciel Vibra4Fake 2020.

De Bleye, C., Cailletaud, J., Dumont, E., Sacré, P.-Y., Gut, Y., Ginot, Y.-M., Hubert, P., & Ziemons, E. (11 October 2019). Application of surface-enhanced Raman chemical imaging (SER-CI) to quantification in pharmaceutical tablets. American Pharmaceutical Review, 22 (6).

Clavaud, M., Lema-Martinez, C., Roggo, Y., Bigalke, M., Guillemain, A., Hubert, P., Ziemons, E., & Allmendinger, A. (24 September 2019). NIR modelling for moisture content determination based on DoE approach. Paper presented at Pharmaceutical freeze drying technology - PDA Exchange Series, Berlin, Germany.

Dumont, E., De Bleye, C., Cailletaud, J., Coic, L., Sacre, P.-Y., Hubert, P., & Ziemons, E. (17 September 2019). Analysing cells and culture media with surface-enhanced Raman scattering (SERS): how to overcome the serum protein problem? Paper presented at 30th International Symposium on Pharmaceutical & Biomedical Analysis - PBA, Tel-Aviv, Israel.

De Bleye, C., Fontaine, M., Sacre, P.-Y., Hubert, P., Theys, N., & Ziemons, E. (16 September 2019). Raman imaging as a new analytical tool for the quality control of the monitoring of osteogenic differentiation in forming 3D bone tissue. Paper presented at 30th International Symposium on Pharmaceutical and Biomedical Analysis, Tel Aviv, Israel.

Beghuin, D., Dumont, E., Emeraud, T., Hubert, P., & Ziemons, E. (02 September 2019). Full field Raman imaging applied to pharmaceutical and biomedical fields: Proof of concept. Paper presented at Full field Raman imaging workshop, Liege, Belgium.

Ciza Hamuli, P.* , Sacre, P.-Y.* , Waffo Tchounga, C., Coic, L., Avohou, T. H., Mbinze, J., Ngono, R., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (01 September 2019). Comparing the qualitative performances of handheld NIR and Raman spectrophotometers for the detection of falsified pharmaceutical products. Talanta, 202, 469-478. doi:10.1016/j.talanta.2019.04.049
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Clavaud, M., Lema-Martinez, C., Roggo, Y., Bigalke, M., Guillemain, A., Hubert, P., Ziemons, E., & Allmendinger, A. (2019). Near-infrared spectroscopy to determine residual moisture in freeze-dried products: Model generation by statistical design of experiments. Journal of Pharmaceutical Sciences. doi:10.1016/j.xphs.2019.08.028
Peer reviewed

Bonnier, F., Chauchard, F., Gut, Y., Michelet, A., Tfayli, A., & Ziemons, E. (July 2019). Chemical Imagnig: An essential mechanism to assess pharmaceutical quality (Part II). STP Pharma Pratiques, 4, 38-55.

Cailletaud, J., De Bleye, C., Gutt, Y., Bultel, L., Leblanc, N., Letellier, P., Ginot, Y.-M., Hubert, P., & Ziemons, E. (25 June 2019). Surface enhanced Raman imaging applied to quality control of solid dosage forms. Paper presented at 7th Annual Conference on Advanced Applied Raman Spectroscopy, Oxford, United Kingdom.

Emonds-Alt, G., Avohou, T. H., Kasemiire, A., Malherbe, C., Monbaliu, J.-C., Ziemons, E., & Eppe, G. (17 June 2019). Integrated microfluidic device for in-line monitoring of glyphosate assisted by Surface Enhanced Raman Spectroscopy. Paper presented at 17th International Conference on Chemistry and the Environment, Thessaloniki, Greece.

Ciza Hamuli, P., Sacre, P.-Y., Waffo Tchounga, C. A., Coic, L., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (14 June 2019). Identification of pharmaceutical products using Handheld NIR and Raman spectrophotometers. Paper presented at Journées Internationales de Recherche en Sciences de la Santé 2019, Lubumbashi, Congo - Brazzaville.

Coic, L.* , Sacre, P.-Y.* , Dispas, A., sakira, A. K., Fillet, M., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (01 June 2019). Comparison of hyperspectral imaging techniques for the elucidation of falsified medicines composition. Talanta, 198, 457-463. doi:10.1016/j.talanta.2019.02.032
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Alaoui Mansouri, M., Sacre, P.-Y., Coic, L., De Bleye, C., Dumont, E., Bouklouze, A., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (20 May 2019). COMPARATIVE STUDY OF ACTIVE PHARMACEUTICAL INGREDIENT QUANTITATION THROUGH THE PACKAGING USING HANDHELD SPECTROPHOTOMETERS BASED ON CONVENTIONAL AND SPATIALLY OFFSET RAMAN SCATTERING. Paper presented at 20th forum of Pharmaceutical Sciences, Brussels, Belgium.

Hamla, S., Sacre, P.-Y., Derenne, A., Goormaghtigh, E., Hubert, P., & Ziemons, E. (20 May 2019). QUALITATIVE AND QUANTITATIVE ANALYSIS OF N-GLYCANS PART OF PHARMACEUTICAL PROTEINS BY FT-IR SPECTROSCOPY. Paper presented at BSPS 20th forum of pharmaceutical sciences.

Deidda, R., Avohou, T. H., Jambo, H., Dispas, A., Orlandini, S., Hubert, P., Ziemons, E., & Hubert, C. (20 May 2019). Principles of Analytical Quality by Design for the development of quality control methods in a pharmaceutical context. Paper presented at 20th Forum of Pharmaceutical Sciences - BSPS, Brussels, Belgium.

Ciza Hamuli, P., Sacre, P.-Y., Waffo Tchounga, C. A., Coic, L., Avohou, T. H., mbinze, J., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (20 May 2019). Detection of falsified pharmaceutical products using Handheld NIR and Raman spectrophotometers. Paper presented at BSPS 2019 Forum of Pharmaceutical Sciences - May 20th 2019 - Brussels, Bruxelles, Belgium.

Coic, L., Sacre, P.-Y., Dispas, A., Fillet, M., Hubert, P., & Ziemons, E. (20 May 2019). HANDHELD RAMAN SPECTROSCOPY: AN ESSENTIAL TOOL TO TACKLE THE SUBSTANDARD MEDICINES ISSUE? Paper presented at BSPS 2019 Forum of Pharmaceutical Sciences, Bruxelles, Belgium.

Waffo Tchounga, C. A., Ciza Hamuli, P., Sacre, P.-Y., Ngono, R., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (20 May 2019). Field survey to evaluate the prevalence of poor quality anti-infective medicines in Cameroon. Paper presented at 20th forum of Pharmaceutical Sciences, Brussels, Belgium.

Bonnier, F., Chauchard, F., Ginot, Y.-M., Gut, Y., Michelet, A., Tfayli, A., & Ziemons, E. (May 2019). Chemical imaging: An essential mechanism to assess pharmaceutical (Part 1). STP Pharma Pratiques, 3, 24-37.

Deidda, R.* , Sacre, P.-Y.* , Clavaud, M., Coic, L., Avohou, T. H., Hubert, P., & Ziemons, E. (May 2019). Vibrational spectroscopy in analysis of pharmaceuticals: Critical review of innovative portable and handheld NIR and Raman spectrophotometers. TrAC: Trends in Analytical Chemistry, 114, 251-259. doi:10.1016/j.trac.2019.02.035
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Hubert, C., Widart, J., Ziemons, E., & Hubert, P. (2019). Process Analysis: Maintenance, Reliability, and Training. In Encyclopedia of Analytical Science 3rd Edition. Elsevier. doi:10.1016/B978-0-12-409547-2.14530-5
Peer reviewed

Ziemons, E., Hubert, C., & Hubert, P. (2019). Process Analysis - Overview. In M. Miro, P. Worsfold (Ed.), A. Townshend (Ed.), & C. Poole (Ed.), Encyclopedia of Analytical Science (3rd Edition, pp. 1-7). Amsterdam, Netherlands: Elsevier. doi:10.1016/B978-0-12-409547-2.14051-X
Peer reviewed

Deidda, R., Avohou, T. H., Kasemiire, A., Dumont, E., De Bleye, C., Hubert, P., Hubert, C., & Ziemons, E. (30 January 2019). Optimisation of a surface enhanced Raman scattering method using design of experiments and Bayesian design space modelling. Poster session presented at Chimiométrie XIX - 2019, Montpellier, France.

Emonts, P., Penoy, N., Rocks, N., Piel, G., Fillet, M., Hubert, P., Ziemons, E., & Evrard, B. (19 January 2019). Update of the progresses and development prospects of the FEDER project Phare. Paper presented at CIRM seminars, Liege, Belgium.

Coic, L., Sacre, P.-Y., Avohou, T. H., Ciza, P., Marini Djang'Eing'A, R., Fillet, M., Hubert, P., & Ziemons, E. (01 January 2019). Authentication of falsified medicine tablets by handheld Raman spectroscopy class modeling. Paper presented at Chimiométrie 2019, Montpellier, France.

Emonts, P., Dispas, A., Ninane, C. (Other coll.), Hubert, P. (Other coll.), Servais, A.-C. (Other coll.), Ziemons, E. (Other coll.), & Fillet, M. (Other coll.). (19 December 2018). Development and optimization of a derivatization protocol for phenethylamine compounds using FITC-CE-LIF method. Poster session presented at 1st CIRM Scientific Day, Liège, Belgium.

Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (19 December 2018). SFC-MS for the quality control of cannabis: addressing the potential adulteration with synthetic cannabinoids. Paper presented at CIRM Day (1st edition).

Dumont, E., De Bleye, C., Cailletaud, J., Sacre, P.-Y., Humblet, S., Vandormael, D., Fleury-Frenette, K., Hubert, P., & Ziemons, E. (19 December 2018). Assessment of the Surface-Enhanced Raman Scattering (SERS) response of solid SERS substrates prepared by innovative techniques. Poster session presented at 1st CIRM Scientific Day, Liège, Belgium.

Coic, L., Sacre, P.-Y., Dispas, A., Fillet, M., Hubert, P., & Ziemons, E. (19 December 2018). Development of graphical user interface (GUI) for database building and for falsification applications. Paper presented at CIRM Day, Belgium.

De Bleye, C., Widart, J., Sacre, P.-Y., Hubert, P., & Ziemons, E. (19 December 2018). Vibra-Santé Hub. Poster session presented at 1st CIRM Scientific Day, Liège, Belgium.

Castiglione, V., Sacre, P.-Y., Cavalier, E., Hubert, P., GADISSEUR, R., & Ziemons, E. (16 November 2018). Raman chemical imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy. Poster session presented at Joint Annual Meeting of the Royal Belgian Society of Laboratory Medicine and the Belgian Thyroid Club.

Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (19 October 2018). SFC-MS as a preventive tool for the quality control of potentially adulterated cannabis with synthetic cannabinoids. Paper presented at SFC 2018, Strasbourg, France.

Cailletaud, J., De Bleye, C., Dumont, E., Sacre, P.-Y., Gut, Y., Bultel, L., Ginot, Y.-M., Hubert, P., & Ziemons, E. (01 October 2018). Towards a spray-coating method for the detection of low-dose compounds in pharmaceutical tablets using surface-enhanced Raman chemical imaging (SER-CI). Talanta, 188, 584-592. doi:10.1016/j.talanta.2018.06.037
Peer Reviewed verified by ORBi

Bonnier, F., Chauchard, F., Ginot, Y.-M., Gut, Y., Michelet, A., Tfayli, A., & Ziemons, E. (18 September 2018). La qualité pharmaceutique passe aussi par l'image: Quelles techniques et savoir-faire utiliser. Paper presented at Session d'Etude SFSTP, Paris, France.

Avohou, T. H., Sacre, P.-Y., Lebrun, P., Hubert, P., & Ziemons, E. (12 September 2018). A novel probabilistic spectral matching strategy based on wavelets regression and Bayesian modeling for product identification and quality verification. Paper presented at 11th International Symposium on Drug Analysis and 29th International Symposium on Pharmaceutical and Biomedical Analysis, DA-PB, Leuven, Belgium.

Dumont, E., De Bleye, C., Cailletaud, J., Deidda, R., Sacre, P.-Y., Van Lerberghe, P.-B., Rogister, B., Hubert, P., & Ziemons, E. (11 September 2018). A simple and easy-to-implement SERS approach overcoming the nanoparticle stabilisation by serum proteins: application to dopamine and PC-12 cells. Paper presented at 11th International Symposium on Drug Analysis - 29th International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2018), Leuven, Belgium.

Clavaud, M., Sacre, P.-Y., Hubert, P., & Ziemons, E. (09 September 2018). Transfer of active pharmaceutical ingredients (API) Raman library from bench top towards handheld spectrometers. Paper presented at International Syposium DA-PBA 2018, Leuven, Belgium.

Cailletaud, J., De Bleye, C., Dumont, E., Sacre, P.-Y., Gut, Y., Ginot, Y.-M., Hubert, P., & Ziemons, E. (September 2018). Detection of low-dose of piroxicam polymorphs in pharmaceutical tablets by surface-enhanced Raman chemical imaging and multivariate analysis. Poster session presented at 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis, Leuven, Belgium.

Ciza Hamuli, P., Waffo Tchounga, C., Coic, L., Mbinze Kindenge, J., Ngono, R., Marini Djang'Eing'A, R., Hubert, P., Sacre, P.-Y., & Ziemons, E. (September 2018). Comparing the qualitative performances of handheld NIR and Raman spectrometers for the analysis of falsified pharmaceutical products. Poster session presented at 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis, Louvain, Belgium.

Coic, L., Sacre, P.-Y., Avohou, T. H., Sakira, K., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (September 2018). Solving composition of falsified artemether/lumefantrine formulation by hyperspectral imaging. Poster session presented at DA-PBA 2018 11th International Symposium on Drug Analysis (DA 2018), 29th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2018).

Sacre, P.-Y., Coic, L., Avohou, T. H., Sakira, K., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (September 2018). Forensic formulation fingerprinting of falsified medicine by Raman hyperspectral imaging. Paper presented at Medicine Quality and Public Health 2018, Oxford, United Kingdom.

Sacre, P.-Y., Avohou, T. H., Lebrun, P., Coic, L., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (September 2018). Bayesian securing of the pharmaceutical supply chain. Paper presented at Medicine Quality and Public Health 2018, Oxford, United Kingdom.

Dumont, E., De Bleye, C., Cailletaud, J., Sacre, P.-Y., Van Lerberghe, P.-B., Rogister, B., Rance, G. A., Aylott, J. W., Hubert, P., & Ziemons, E. (15 August 2018). Development of a SERS strategy to overcome the nanoparticle stabilisation effect in serum-containing samples: Application to the quantification of dopamine in the culture medium of PC-12 cells. Talanta, 186, 8-16. doi:10.1016/j.talanta.2018.04.038
Peer Reviewed verified by ORBi

Castiglione, V., Sacre, P.-Y., CAVALIER, E., Hubert, P., GADISSEUR, R., & Ziemons, E. (03 August 2018). Raman Chemical Imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy. PLoS ONE, 13 (8), 0201460. doi:10.1371/journal.pone.0201460
Peer Reviewed verified by ORBi

Alaoui Mansouri, M., Sacre, P.-Y., Ziemons, E., kharbach, M., Cherrah, Y., Hubert, P., Bouklouze, A., & Marini Djang'Eing'A, R. (26 June 2018). CLASSIFICATION OF FLUCONAZOLE API POLYMORPHIC FORMS IN PHARMACEUTICAL PRODUCTS BY ASSOCIATING FTIR, NIR AND RAMAN TO PLS-DA. Poster session presented at Chemometrics in analytical chemistry XVII, Halifax, Canada.

Nguyen, T. D., Dortu, F., Dispas, A., Hubert, P., Ziemons, E., & Hernandez, Y. (28 May 2018). Terahertz hyper-spectral imaging of lab-prepared versus commercial paracetamol tablets and potential applications. Proceedings of SPIE: The International Society for Optical Engineering, 1067731, 1-7. doi:10.1117/12.2307648
Peer reviewed

Dumont, E., De Bleye, C., Cailletaud, J., Deidda, R., Sacre, P.-Y., Hubert, P., & Ziemons, E. (24 May 2018). About the use of surface-enhanced Raman scattering to monitor the cellular release of neurotransmitters. Paper presented at 11e Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique, Liège, Belgium.

Dumont, E., De Bleye, C., Cailletaud, J., Deidda, R., Sacre, P.-Y., Hubert, P., & Ziemons, E. (17 May 2018). Investigation of solid surface-enhanced Raman scattering (SERS) substrates for the quantification of dopamine in cell culture media. Poster session presented at Bioforum of BioLiège 2018, Liège, Belgium.

De Bleye, C., Cailletaud, J., Deidda, R., Dumont, E., Hubert, P., & Ziemons, E. (16 May 2018). Application of surface-enhanced Raman spectroscopy (SERS) in the biological and the pharmaceutical fields: state of the art and new perspectives. Paper presented at Séminaire mensuel du CIRM, Liège, Belgium.

Coic, L., Castiglione, V., Sacre, P.-Y., Hubert, P., GADISSEUR, R., CAVALIER, E., & Ziemons, E. (May 2018). Elucidation de la structure de la lithiase urinaire par imagerie IR-TF. Poster session presented at 11èmes journées scientifiques du Réseau Français de Métabolomique et Fluxomique, Liege, Belgium.

Nguyen, D., Dortu, F., Dispas, A., Hubert, P., Ziemons, E., & Hernandez, Y. (25 April 2018). Terahertz hyperspectral imaging of lab-prepared versus commercial paracetamol tablets and potential applications. Poster session presented at SPIE Photonics Europe, Strasbourg, France.

Dumont, E., De Bleye, C., Cailletaud, J., Sacre, P.-Y., Hubert, P., & Ziemons, E. (2018). Development of a surface-enhanced Raman scattering strategy to quantify dopamine in cell culture media. (ULiège - Université de Liège, LANG5002-1 Advanced English for Biomedical Science 2).

De Leersnyder, F., Vanhoorne, V., Bekaert, H., Vercruysse, J., Ghijs, M., Bostijn, N., Verstraeten, M., Cappuyns, P., Van Assche, I., Vander Heyden, Y., Ziemons, E., Remon, J. P., Nopens, I., Vervaet, C., & De Beer, T. (20 January 2018). Breakage and drying behaviour of granules in a continuous fluid bed dryer: Influence of process parameters and wet granule transfer. European Journal of Pharmaceutical Sciences, 115, 223-232. doi:10.1016/j.ejps.2018.01.037
Peer Reviewed verified by ORBi

De Leersnyder, F., Peeters, E., Djalabi, H., Vanhoorne, V., Van Snick, B., Hong, K., Hammond, S., Liu, A. Y., Ziemons, E., Vervaet, C., & De Beer, T. (17 January 2018). Development and validation of an in-line NIR spectroscopic method for continuous blend potency determination in the feed frame of a tablet press. Journal of Pharmaceutical and Biomedical Analysis, 151, 274-283. doi:10.1016/j.jpba.2018.01.032
Peer Reviewed verified by ORBi

Avohou, T. H., Cailletaud, J., Clavaud, M., Coic, L., De Bleye, C., Deidda, R., Dumont, E., Sacre, P.-Y., Hubert, P., & Ziemons, E. (15 January 2018). De l'intérêt de la spectroscopie Raman pour l'analyse pharmaceutique. Paper presented at Conférence Universitaire de Suisse Occidentale, Genève, Switzerland.

Cailletaud, J., De Bleye, C., Dumont, E., Sacre, P.-Y., Netchacovitch, L., Gut, Y., Boiret, M., Ginot, Y.-M., Hubert, P., & Ziemons, E. (05 January 2018). Critical review of surface-enhanced Raman spectroscopy applications in the pharmaceutical field. Journal of Pharmaceutical and Biomedical Analysis, 147, 458-472. doi:10.1016/j.jpba.2017.06.056
Peer Reviewed verified by ORBi

De Bleye, C., Dumont, E., Hubert, C., Jambo, H., Lejeune, R., Ziemons, E., & Hubert, P. (2018). Pré-requis aux travaux pratiques de chimie analytique - Deuxième baccalauréat en Sciences pharmaceutiques. (ULiège - Université de Liège, Belgium, CHIM0321-3 Travaux pratiques - Introduction à la chimie analytique).

De Bleye, C., Dumont, E., Hubert, C., Jambo, H., Lejeune, R., Ziemons, E., & Hubert, P. (2018). Travaux Pratiques: Introduction à la Chimie Analytique Pharmaceutique_Présentation.

De Bleye, C., Dumont, E., Hubert, C., Jambo, H., Lejeune, R., Ziemons, E., & Hubert, P. (2018). Notes des travaux pratiques de chimie analytique - Deuxième baccalauréat en Sciences pharmaceutiques. (ULiège - Université de Liège, Belgium, CHIM0321-3 Travaux pratiques - Introduction à la chimie analytique).

Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (2018). Implementation of a generic SFC-MS method for the quality control of potentially counterfeited medicinal cannabis with synthetic cannabinoids. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1092, 332-342. doi:10.1016/j.jchromb.2018.05.049
Peer Reviewed verified by ORBi

Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (2018). Quality control of medicinal cannabis: implementation of a generic sfc-ms method to address counterfeiting with synthetic cannabinoids. Poster session presented at International Symposium DA-PBA 2018, Leuven, Belgium.

Coic, L., Sacre, P.-Y., Avohou, T. H., Deidda, R., De Bleye, C., Dumont, E., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (2018). Recent developments of Raman spectroscopy for the qualitative analysis of falsified and substandard medicines. European Pharmaceutical Review.

Ziemons, E. (22 November 2017). Approches intégrées en Sciences Pharmaceutiques. Paper presented at Semaine de l'Enseignement, Liège, Belgium.

Castiglione, V., Sacre, P.-Y., CAVALIER, E., Hubert, P., GADISSEUR, R., & Ziemons, E. (02 November 2017). Raman Chemical Imaging in Kidney Stone Analysis. Poster session presented at American Society of Nephrology Kidney Week 2017 Annual Meeting, New Orleans, United States.

Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2017). NETTOYAGE DES EQUIPEMENTS ET VALIDATION DE NETTOYAGE - 2017.

Adar, F., Boiret, M., Netchacovitch, L., & Ziemons, E. (10 October 2017). Determination of the crystalline content of an amorphous solid dispersion produced by hot-melt extrusion. Paper presented at SciX - The great SCIentific eXchange, Reno, NV, United States.

Marini Djang'Eing'A, R., Sacre, P.-Y., Ziemons, E., & Hubert, P. (04 October 2017). Poor quality medicines in Africa: how to combat this real scourge. Paper presented at 5th Annual International Scientific Conference Society for the Advancement of Science in Africa (SASA) and 2nd Rwanda Biotechnology Conference, Kigali, Rwanda.

Cailletaud, J., De Bleye, C., Dumont, E., Jambo, H., Sacre, P.-Y., Gut, Y., Bultel, L., Ginot, Y.-M., Hubert, P., & Ziemons, E. (22 September 2017). Towards a covering aerospray method for quantitative analyses of pharmaceutical tablets using surface-enhanced Raman chemical imaging (SER-CI). Paper presented at Recent Developments in Pharmaceutical Analysis - RDPA 2017, Rimini, Italy.

Dumont, E., De Bleye, C., Cailletaud, J., Jambo, H., Sacre, P.-Y., Aylott, J., Hubert, P., & Ziemons, E. (21 September 2017). Towards the development of a dual mode fluorescence/SERS dopamine aptasensor. Poster session presented at Recent Developments in Pharmaceutical Analysis - RDPA 2017, Rimini, Italy.

Avohou, T. H., Cailletaud, J., Clavaud, M., De Bleye, C., Dumont, E., Marini Djang'Eing'A, R., Sacre, P.-Y., Hubert, P., & Ziemons, E. (20 September 2017). Modern spectral analyses fro drug identification and quantification: From PAT to patient protection. Paper presented at Arlenda Day, Bruxelles, Belgium.

Dumont, E., De Bleye, C., Cailletaud, J., Jambo, H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (13 September 2017). Development of SERS nanosensors for the detection of small bioactive molecules by cellular analysis in complex matrices: Application to dopamine. Paper presented at PhD Day of the EDT Sciences Pharmaceutiques, Spa, Belgium.

Andri, B., Dispas, A., Klinkenberg, R., Streel, B., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (27 July 2017). Is supercritical fluid chromatography hyphenated to massspectrometry suitable for the quality control of vitamin D3 oilyformulations? Journal of Chromatography. A, 1515, 209-217. doi:10.1016/j.chroma.2017.07.057
Peer Reviewed verified by ORBi

Clavaud, M., Roggo, Y., Degardin, K., Sacre, P.-Y., Hubert, P., & Ziemons, E. (15 July 2017). Global regression model for moisture content determination using near-infrared spectroscopy. European Journal of Pharmaceutics and Biopharmaceutics, 119, 343-352. doi:10.1016/j.ejpb.2017.07.007
Peer Reviewed verified by ORBi

Clavaud, M., Roggo, Y., Allmendinger, A., Martinez, C., Hubert, P., & Ziemons, E. (11 June 2017). Impact of formulation and process parameters on near-infrared spectra: Application for water determination in biopharmaceuticals. Poster session presented at 18th International Conference on Near Infrared Spectroscopy, Copenhagen, Denmark.

Sacre, P.-Y., Netchacovitch, L., Dumont, E., Cailletaud, J., De Bleye, C., Boiret, M., Hubert, P., & Ziemons, E. (2017). Raman Hyperspectral Imaging: An essential tool in the pharmaceutical field. Eprint/Working paper retrieved from https://orbi.uliege.be/2268/211869.

Clavaud, M., Roggo, Y., Dégardin, K., Lema-Martinez, C., Hubert, P., & Ziemons, E. (2017). Online-Restwasserbestimmung. ChemieXtra: die Fachzeitschrift für die Chemie- und Laborbranche.

Netchacovitch, L., Thiry, J., De Bleye, C., Dumont, E., Cailletaud, J., Sacre, P.-Y., Evrard, B., Hubert, P., & Ziemons, E. (26 April 2017). Global approach for the validation of an in-line Raman spectroscopic method to determine the API content in real-time during a hot-melt extrusion process. Talanta, 171, 45-52. doi:10.1016/j.talanta.2017.04.060
Peer Reviewed verified by ORBi

Marini Djang'Eing'A, R., Ziemons, E., Sacre, P.-Y., & Hubert, P. (2017). Le fléau des faux médicaments. Paper presented at Médicaments ou poisons, Liège, Belgium.

Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Hubert, P., & Ziemons, E. (2017). Raman Hyperspectral Imaging: An essential tool in the pharmaceutical field. Paper presented at Live Webinar, Paris, France.

Andri, B., Dispas, A., Klinkenberg, R., Streel, B., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (28 March 2017). Validation des performances quantitatives d'une méthode SFC-MS pour le contrôle de qualité d'un médicament : le cas de la vitamine D3. Poster session presented at SEP 2017, Paris, France.

Netchacovitch, L., Dumont, E., Cailletaud, J., Thiry, J., De Bleye, C., Sacre, P.-Y., Boiret, M., Evrard, B., Hubert, P., & Ziemons, E. (2017). Development of an analytical method for crystalline content determination in amorphous solid dispersions produced by Hot-Melt Extrusion using transmission Raman spectroscopy: A feasibility study. International Journal of Pharmaceutics, 530 (1-2), 249-255. doi:10.1016/j.ijpharm.2017.07.052
Peer Reviewed verified by ORBi

Andri, B., Lebrun, P., Dispas, A., Klinkenberg, R., Streel, B., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (2017). Optimization and validation of a fast Supercritical Fluid Chromatography method for the quantitative determination of vitamin D3 and its related impurities. Journal of Chromatography. A. doi:10.1016/j.chroma.2017.01.090
Peer Reviewed verified by ORBi

Thiry, J., Lebrun, P., Vinassa, C., Adam, M., Netchacovitch, L., Ziemons, E., Hubert, P., Krier, F., & Evrard, B. (30 December 2016). Continuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination. International Journal of Pharmaceutics, 515 (1-2), 114-124. doi:10.1016/j.ijpharm.2016.10.003
Peer Reviewed verified by ORBi

Dumont, E., De Bleye, C., Cailletaud, J., Sacre, P.-Y., Netchacovitch, L., Van Lerberghe, P.-B., Rogister, B., Hubert, P., & Ziemons, E. (16 November 2016). Development of a quantitative surface-enhanced Raman scattering method for the analysis of dopamine in cell culture media. Poster session presented at The Bioforum 2016 of BioLiège, Liège, Belgium.

Netchacovitch, L., Thiry, J., De Bleye, C., Dumont, E., Sacre, P.-Y., Evrard, B., Hubert, P., & Ziemons, E. (17 October 2016). Determination of the analytical performances of an in-line Raman spectroscopic method monitoring a hot-melt extrusion process. Paper presented at 19th Forum of Pharmaceutical Sciences, Bruxelles, Belgium.

Dispas, A., Lebrun, P., Ziemons, E., & Hubert, P. (07 October 2016). SFC: A green alternative for quantitative analysis in the pharmaceutical field? Paper presented at SFC 2016, Vienna, Austria.

Andri, B., Lebrun, P., Dispas, A., Klinkenberg, R., Streel, B., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (October 2016). A fully validated UHPSFC method for the quality control of vitamin D3 as an alternative to pharmacopeias NPLC methods. Poster session presented at 10th International Conference on Packed-column SFC - SFC2016, Vienna, Austria.

Clavaud, M., Roggo, Y., Dégardin, K., Sacre, P.-Y., Hubert, P., & Ziemons, E. (13 September 2016). Moisture content determination in an antibody-drug conjugate freeze-dried medicine by near-infrared spectroscopy: a case study for release testing. Journal of Pharmaceutical and Biomedical Analysis, 131, 380-390. doi:10.1016/j.jpba.2016.09.014
Peer Reviewed verified by ORBi

De Bleye, C., Dumont, E., Dispas, A., Hubert, C., Sacre, P.-Y., Netchacovitch, L., De Muyt, B., Kevers, C., Dommes, J., Hubert, P., & Ziemons, E. (August 2016). Monitoring of anatabine release by methyl jasmonate elicited BY-2 cells using surface-enhanced Raman scattering. Talanta, 160, 754-760. doi:10.1016/j.talanta.2016.08.027
Peer Reviewed verified by ORBi

Netchacovitch, L., Thiry, J., De Bleye, C., Dumont, E., Dispas, A., Hubert, C., Krier, F., Sacre, P.-Y., Evrard, B., Hubert, P., & Ziemons, E. (July 2016). A simple calibration approach based on film-casting for confocal Raman microscopy to support the development of a Hot-Melt Extrusion process. Talanta, 154, 392-399. doi:10.1016/j.talanta.2016.03.080
Peer Reviewed verified by ORBi

Clavaud, M., Roggo, Y., Degardin, K., Hubert, P., & Ziemons, E. (06 June 2016). MOISTURE CONTENT DETERMINATION OF FREEZE-DRIED PRODUCTS BY NEAR-INFRARED SPECTROSCOPY: A CASE STUDY FOR UNIVERSAL REGRESSION MODEL. Poster session presented at XVI Chemometrics in Analytical Chemistry, Barcelona, Spain.

Sacre, P.-Y., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (Other coll.). (2016). Médicaments usage de faux. Moustique.

De Bleye, C., Dumont, E., Dispas, A., Hubert, C., Sacre, P.-Y., Netchacovitch, L., De Muyt, B., Kevers, C., Dommes, J., Hubert, P., & Ziemons, E. (19 May 2016). Use of SERS to monitor the anatabine release in the culture medium by methyl jasmonate elicited BY-2 cells. Poster session presented at Raman Fest 2016, Berlin, Germany.

Servais, A.-C., & Ziemons, E. (13 May 2016). Approches intégrées en Sciences Pharmaceutiques. Paper presented at 9ème Journée Annuelle de l'IFRES: De solitaire à solidaire, vivre la pédagogie universitaire en équipe, Sart-Tilman, Belgium.

Dumont, E., De Bleye, C., Sacre, P.-Y., Netchacovitch, L., Hubert, P., & Ziemons, E. (15 April 2016). From Near-Infrared and Raman to Surface-Enhanced Raman Spectroscopy: Progress, Limitations, Perspectives in Bioanalysis. Bioanalysis, 8 (10), 1077-1103. doi:10.4155/bio-2015-0030
Peer Reviewed verified by ORBi

Andri, B., Dispas, A., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (2016). First-International In-SCrit - Rapport d'activité 4. (4).

Baldacci-Cresp, F., Sacre, P.-Y., Twyffels, L., Mol, A., Vermeersch, M., Ziemons, E., Hubert, P., Pérez-Morga, D., El Jarizi, M., de Almeida-Engler, J., & Baucher, M. (2016). Poplar-root-knot nematode interaction: a model for perennial woody species. Molecular Plant-Microbe Interactions, 29 (7), 560-572. doi:10.1094/MPMI-01-16-0015-R
Peer Reviewed verified by ORBi

Habyalimana, V., Mbinze Kindenge, J., Kalenda Tshilombo, N., Dispas, A., Yemoa Loconon, A., Sacre, P.-Y., Widart, J., De Tullio, P., Counerotte, S., Kadima Ntokamunda, J.-L., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (02 December 2015). Analytical Tools and Strategic Approach to Detect Poor Quality Medicines, Identify Unknown Components, and Timely Alerts for Appropriate Measures: Case Study of Antimalarial Medicines. American Journal of Analytical Chemistry, 6, 977-994. doi:10.4236/ajac.2015.613093
Peer reviewed

Thiry, J., Lebrun, P., Netchacovitch, L., Ziemons, E., Hubert, P., Krier, F., & Evrard, B. (23 November 2015). Production of Itraconazole/Soluplus® Extrudates: Optimization of Both Formulation and Hot-Melt Extrusion Process Through a Single Design of Experiment. Paper presented at Biopharmacy Day 2015, Leuven, Belgium.

Chavez, P.-F., Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Mantanus, J., Motte, H., Schubert, M., Hubert, P., & Ziemons, E. (01 November 2015). Active content determination of pharmaceutical tablets using near infrared spectroscopy as Process Analytical Technology tool. Talanta, 144, 1352–1359. doi:10.1016/j.talanta.2015.08.018
Peer Reviewed verified by ORBi

Dumont, E., De Bleye, C., Sacre, P.-Y., Netchacovitch, L., Hubert, P., & Ziemons, E. (29 October 2015). Développement de nanosenseurs SERS pour la détection de molécules actives dans des matrices biologiques. Paper presented at Séminaire du CIRM : Présentation des projets des nouveaux chercheurs du centre, Liège, Belgium.

Ziemons, E. (2015). Pour analyser la qualité des médicaments. Eprint/Working paper retrieved from https://orbi.uliege.be/2268/186902.

Thiry, J., Lebrun, P., Netchacovitch, L., Pestieau, A., Ziemons, E., Hubert, P., Krier, F., & Evrard, B. (October 2015). Production of Itraconazole/Soluplus® Extrudates: Optimization of Both Formulation and Hot-Melt Extrusion Process Through a Single Design of Experiment. Poster session presented at AAPS Orlando 2015.

Andri, B., Dispas, A., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (2015). First-International In-SCrit - Rapport d'activité 3. (3).

Netchacovitch, L., Thiry, J., De Bleye, C., Chavez, P.-F., Krier, F., Sacre, P.-Y., Evrard, B., Hubert, P., & Ziemons, E. (September 2015). Vibrational spectroscopy and microspectroscopy analyzing qualitatively and quantitatively pharmaceutical hot melt extrudates. Journal of Pharmaceutical and Biomedical Analysis, 113, 21-33. doi:10.1016/j.jpba.2015.01.051
Peer Reviewed verified by ORBi

De Bleye, C., Dumont, E., Hubert, C., Sacre, P.-Y., Netchacovitch, L., Chavez, P.-F., Hubert, P., & Ziemons, E. (August 2015). A simple approach for ultrasensitive detection of bisphenols by multiplexed surface-enhanced Raman scattering. Analytica Chimica Acta, 888, 118-125. doi:10.1016/j.aca.2015.07.023
Peer Reviewed verified by ORBi

De Bleye, C., Dumont, E., Netchacovitch, L., Chavez, P.-F., Sacre, P.-Y., Hubert, P., & Ziemons, E. (13 July 2015). Development of a simple approach for ultrasensitive detection of bisphenols by multiplexed surface enhanced Raman scattering. Poster session presented at 8th International Conference on Advanced Vibrational Spectroscopy - ICAVS, Vienna, Austria.

Mbinze Kidenge, J.* , Sacre, P.-Y.* , Yemoa, A., Mavar Tayey Mbay, J., Habyalimana, V., Kalenda, N., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (10 July 2015). Development, validation and comparison of NIR and Raman methods for the identification and assay of poor-quality oral quinine drops. Journal of Pharmaceutical and Biomedical Analysis, 111, 21-27. doi:10.1016/j.jpba.2015.02.049
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Chavez, P.-F., Lebrun, P., Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Cuypers, S., Mantanus, J., Motte, H., Schubert, M., Evrard, B., Hubert, P., & Ziemons, E. (30 May 2015). Optimization of a Pharmaceutical Tablet Formulation based on a Design Space Approach and using Vibrational Spectroscopy as PAT Tool. International Journal of Pharmaceutics, 486 (1-2), 13-20. doi:10.1016/j.ijpharm.2015.03.025
Peer Reviewed verified by ORBi

Habyalimana, V., Dispas, A., Sacre, P.-Y., Widart, J., De Tullio, P., Counerotte, S., Kadima, N. J., Ziemons, E., Hubert, P., & Marini Djang'Eing'A, R. (28 May 2015). USE OF SIMPLE AND COMPLEX ANALYTICAL TOOLS TO DETECT POOR QUALITY MEDICINES: CASE OF RWANDA. Paper presented at 18th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Netchacovitch, L., Thiry, J., De Bleye, C., Chavez, P.-F., Krier, F., Sacre, P.-Y., Evrard, B., Hubert, P., & Ziemons, E. (21 May 2015). Analysis of film casting by Raman confocal microscopy: An innovative approach in the framework of drug content and API solid-state determination. Paper presented at Forum des jeunes chercheurs, Namur, Belgium.

Ziemons, E., Hubert, C., Marini Djang'Eing'A, R., Rozet, E., Lebrun, P., Boulanger, B., & Hubert, P. (12 May 2015). Validation des méthodes analytiques: Approche basée sur l'erreur totale. Paper presented at Chimie Analytique et chimie des eaux, Mons, Belgium.

Ziemons, E., Chavez, P.-F., Netchacovitch, L., De Bleye, C., Sacre, P.-Y., & Hubert, P. (29 April 2015). Intérêt de la spectroscopie vibrationnelle dans le cadre de l'analyse pharmaceutique. Paper presented at Séminaire de l'école doctorale thématique en Sciences Pharmaceutiques, Bruxelles, Belgium.

Sacre, P.-Y., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2015). Médicaments: Faux et usage de faux. Athena, (310), p. 19-22.

Sacre, P.-Y., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (April 2015). Médicaments: Faux et usage de faux. Tempo Médical, 377, p. 33-36.

Marini Djang'Eing'A, R., Mbinze, K., Sacre, P.-Y., Ziemons, E., & Hubert, P. (2015). Falsification des médicaments (Falsification des médicaments et conséquences pour la santé publique : cas de l’Afrique subsaharienne ). (ULiège - Université de Liège).

Ziemons, E., Sacre, P.-Y., Marini Djang'Eing'A, R., & Hubert, P. (2015). Falsification des médicaments: Est-il possible d'améliorer la puissance des outils de détection ? Paper presented at Liège Créative, Liège, Belgium.

Andri, B., Dispas, A., Ziemons, E., & Hubert, P. (2015). First International In-Scrit - rapport d'activités 2 ( 08/2014 - 01/2015). (2).

Sacre, P.-Y., Lebrun, P., Chavez, P.-F., De Bleye, C., Netchacovitch, L., Hubert, P., & Ziemons, E. (20 January 2015). Distributional homogeneity index (DHI), a valuable tool during pharmaceutical development. Paper presented at Chimiométrie XVI, Genève, Switzerland.

Clavaud, M., Roggo, Y., Hubert, P., & Ziemons, E. (January 2015). Moisture content determination of a new antibody-drug conjugate lyophilize by Near-Infrared Spectroscopy (NIRS) for release and stability analysis. Poster session presented at Chimiométrie XVI, Genève, Switzerland.

Netchacovitch, L., Thiry, J., De Bleye, C., Chavez, P.-F., Sacre, P.-Y., Krier, F., Evrard, B., Hubert, P., & Ziemons, E. (January 2015). Confocal Raman microscopy to support the development of an extrusion process: a quantitative approach based on film casting. Poster session presented at CHimiometrie XVI, Genève, Switzerland.

Thiry, J., Netchacovitch, L., Krier, F., Ziemons, E., Hubert, P., & Evrard, B. (2015). Determination of the Crystal Content within an Itraconazole-based extrudate : Comparison between Differential Scanning Calorimetry and Raman techniques. Poster session presented at TA Instruments' BeNeLux Users Meeting & Symposium 2015.

Sacre, P.-Y., Netchacovitch, L., De Bleye, C., Chavez, P.-F., Servais, C., Klinkenberg, R., Streel, B., Hubert, P., & Ziemons, E. (2015). Thorough characterization of a Self-Emulsifying Drug Delivery System with Raman hyperspectral imaging: A case study. International Journal of Pharmaceutics, 484, 85-94. doi:10.1016/j.ijpharm.2015.02.052
Peer Reviewed verified by ORBi

Sakira, A. K., Somé, I. T., Ziemons, E., Dejaegher, B., Mertens, D., Hubert, P., & Kauffmann, J.-M. (2015). Determination of arsenic (III) at a nano gold modified solid carbon paste electrode. Electroanalysis, 27, 309-316. doi:10.1002/elan.201400485
Peer Reviewed verified by ORBi

Ziemons, E., Chavez, P.-F., Netchacovitch, L., De Bleye, C., Sacre, P.-Y., & Hubert, P. (13 November 2014). Intérêt de la spectroscopie vibrationnelle dans le cadre du PAT. Paper presented at Séminaire du CIRM, Liège, Belgium.

Chavez, P.-F., Lebrun, P., Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Mantanus, J., Motte, H., Schubert, M., Hubert, P., & Ziemons, E. (13 November 2014). Optimization of a Pharmaceutical Tablet Formulation using a Design Space Approach and Vibrational Spectroscopy as PAT Tool. Paper presented at Séminaire du CIRM, Liège, Belgium.

Netchacovitch, L., De Bleye, C., Chavez, P.-F., Sacre, P.-Y., Hubert, P., & Ziemons, E. (November 2014). Raman hyperspectral imaging: a single tool to characterise pharmaceutical products. European Pharmaceutical Review, 19 (5), 8-11.

Chavez, P.-F., Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Mantanus, J., Motte, H., Schubert, M., Hubert, P., & Ziemons, E. (November 2014). Determination of API Content in Proportional Pharmaceutical Tablet Forms by Near Infrared Spectroscopy. Poster session presented at 2014 AAPS Annual Meeting and Exposition, San Diego, United States - California.

Sacre, P.-Y., De Bleye, C., Chavez, P.-F., Netchacovitch, L., Hubert, P., & Ziemons, E. (October 2014). Data processing of vibrational chemical imaging for pharmaceutical applications. Journal of Pharmaceutical and Biomedical Analysis, 101, 123-140. doi:10.1016/j.jpba.2014.04.012
Peer Reviewed verified by ORBi

Dispas, A., Lebrun, P., Ziemons, E., Marini Djang'Eing'A, R., Rozet, E., & Hubert, P. (August 2014). Evaluation of the quantitative performances of Supercritical Fluid Chromatography : from method development to validation. Journal of Chromatography. A, 1353 (Method Validation), 78-88. doi:10.1016/j.chroma.2014.01.046
Peer Reviewed verified by ORBi

Andri, B., Dispas, A., Ziemons, E., & Hubert, P. (2014). Projet First International In-SCrit - rapport d'activités 1 (02/2014 - 08/2014). (1).

De Bleye, C., Dumont, E., Sacre, P.-Y., Chavez, P.-F., Netchacovitch, L., Piel, G., Hubert, P., & Ziemons, E. (23 June 2014). Development of a multiplexed surface-enhanced Raman scattering quantitative approach for bisphenols detection. Paper presented at Drug Analysis 2014, Liège, Belgium.

Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Chavez, P.-F., Klinkenberg, R., Streel, B., Hubert, P., & Ziemons, E. (June 2014). Application of hyperspectral Raman imaging to the analysis of a self-emulsifying drug delivery system (SEDDS). Poster session presented at Drug Analysis 2014.

Netchacovitch, L., Thiry, J., De Bleye, C., Sacre, P.-Y., Chavez, P.-F., Krier, F., Evrard, B., Hubert, P., & Ziemons, E. (June 2014). Confocal Raman microscopy to support the development of an extrusion process by qualitative and quantitative analyses. Poster session presented at Drug Analysis 2014.

Pestieau, A., Krier, F., Thoorens, G., Dupont, A., Chavez, P.-F., Ziemons, E., Hubert, P., & Evrard, B. (June 2014). Towards a real time release approach for manufacturing tablets using NIR spectroscopy. Poster session presented at Drug Analysis 2014, Liège, Belgium.

Chavez, P.-F., Netchacovitch, L., Sacre, P.-Y., De Bleye, C., Lebrun, P., Motte, H., Schubert, M., Evrard, B., Hubert, P., & Ziemons, E. (June 2014). Optimization of a Pharmaceutical Tablet Formulation using a Design Space Approach and Vibrational Spectroscopy as PAT Tool. Poster session presented at Drug Analysis 2014, Liège, Belgium.

Netchacovitch, L., De Bleye, C., Sacre, P.-Y., Chavez, P.-F., Hubert, P., & Ziemons, E. (15 May 2014). Qualitative and quantitative analyses of a pharmaceutical formulation produced by hot melt extrusion using Raman spectroscopy. Poster session presented at Bioforum 2014, Liège, Belgium.

De Bleye, C., Dumont, E., Sacre, P.-Y., Chavez, P.-F., Netchacovitch, L., Piel, G., Hubert, P., & Ziemons, E. (15 May 2014). Development of an analytical method to detect simultaneously bisphenols using a multiplexed surface-enhanced Raman scattering quantitative approach. Poster session presented at The Bioforum 2014 of BioLiège, Liège, Belgium.

Sacre, P.-Y., Deconinck, E., Marini Djang'Eing'A, R., Ziemons, E., Hubert, P., CHIAP, P., Crommen, J., & De Beer, J. O. (May 2014). Stratégies analytiques pour la détection de contrefaçons de médicaments pour la dysfonction érectile. Spectra Analyse, 43, 37.
Peer reviewed

Pestieau, A., Krier, F., Thoorens, G., Dupont, A., Chavez, P.-F., Ziemons, E., Hubert, P., & Evrard, B. (May 2014). Towards a real time release approach for manufacturing tablets using NIR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 98, 60-67. doi:10.1016/j.jpba.2014.05.002
Peer Reviewed verified by ORBi

Mbinze Kindenge, J., Kalenda Tshilombo, N., Chavez, P.-F., De Bleye, C., Sacre, P.-Y., Mavar Tayey Mbay, J., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (May 2014). La spectroscopie proche infrarouge, une technique non destructive dans la lutte contre la contrefaçon des médicaments. Spectra Analyse, 43, 43.
Peer reviewed

Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Chavez, P.-F., Hubert, P., & Ziemons, E. (08 April 2014). Intérêt de l'imagerie Raman pour l'analyse de préparations pharmaceutiques. Paper presented at CIRM.

Some, I., Guel, B., Hantson, A.-L., Hubert, P., Ziemons, E., Mertens, D., & Kauffmann, J.-M. (19 March 2014). Contribution à l'amélioration de l'accès à une eau potable de qualité pour les populations de la région nord du Burkina Faso. Poster session presented at 7ème Journée de la Coopération, Bruxelles, Belgium.

De Bleye, C.* , Sacre, P.-Y.* , Dumont, E., Netchacovitch, L., Chavez, P.-F., Piel, G., Lebrun, P., Hubert, P., & Ziemons, E. (05 March 2014). Development of a quantitative approach using surface-enhanced Raman chemical imaging: First step for the determination of an impurity in a pharmaceutical model. Journal of Pharmaceutical and Biomedical Analysis, 90, 111-118. doi:10.1016/j.jpba.2013.11.026
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Hubert, C., Lebrun, P., Houari, S., Ziemons, E., Rozet, E., & Hubert, P. (25 January 2014). Improvement of a stability-indicating method by Quality-by-Design versus Quality-by-Testing: A case of a learning process. Journal of Pharmaceutical and Biomedical Analysis, 88, 401-409. doi:10.1016/j.jpba.2013.09.026
Peer Reviewed verified by ORBi

De Bleye, C., Sacre, P.-Y., Dumont, E., Chavez, P.-F., Netchacovitch, L., Piel, G., Rozet, E., Lebrun, P., Hubert, P., & Ziemons, E. (20 January 2014). Quantitative approaches based on Surface-Enhanced Raman Scattering (SERS) and Surface-Enhanced Raman Chemical Imaging (SER-CI). Paper presented at Forum des jeunes chercheurs, Liège, Belgium.

Sacre, P.-Y., Lebrun, P., Chavez, P.-F., De Bleye, C., Netchacovitch, L., Rozet, E., Klinkenberg, R., Streel, B., Hubert, P., & Ziemons, E. (2014). A new criterion to assess distributional homogeneity in hyperspectral images of solid pharmaceutical dosage forms. Analytica Chimica Acta, 818, 7-14. doi:10.1016/j.aca.2014.02.014
Peer Reviewed verified by ORBi

Ginot, Y.-M., Bernard-Moulin, P., Boiret, M., Cinier, R., Despagne, F., Dubost, J. P., Francès, L., Le Page, M., Michelet, A., Meunier, L., & Ziemons, E. (January 2014). Quantitative analysis using near infrared spectroscopy, application to tablet content uniformity test, II. STP Pharma Pratiques, 24 (1), 3-36.

De Bleye, C., Dumont, E., Rozet, E., Sacre, P.-Y., Chavez, P.-F., Netchacovitch, L., Piel, G., Hubert, P., & Ziemons, E. (15 November 2013). Determination of 4-aminophenol in a pharmaceutical formulation using Surface Enhanced Raman scattering: from development to method validation. Talanta, 116, 899-905. doi:10.1016/j.talanta.2013.07.084
Peer Reviewed verified by ORBi

Pestieau, A., Krier, F., Thoorens, G., Dupont, A., Chavez, P.-F., Ziemons, E., Hubert, P., & Evrard, B. (November 2013). Real time release approach in terms of four Pharmacopoeia tests for tablets manufacturing using NIR spectroscopy. Poster session presented at AAPS Annual Meeting and Exposition, San Antonio, United States.

Netchacovitch, L., Sacre, P.-Y., Chavez, P.-F., De Bleye, C., Hubert, P., & Ziemons, E. (17 October 2013). Raman chemical imaging as qualitative and quantitative tool to characterize solid pharmaceutical formulations. Paper presented at 17th Forum of Pharmaceutical Sciences, Spa, Belgium.

De Bleye, C., Sacre, P.-Y., Dumont, E., Chavez, P.-F., Netchacovitch, L., Piel, G., Rozet, E., Lebrun, P., Hubert, P., & Ziemons, E. (17 October 2013). Development of a quantitative approach based on surface-enhanced Raman chemical imaging (SER-CI). Paper presented at Belgian Society of Pharmaceutical Sciences, Spa, Belgium.

Ginot, Y.-M., Bernard-Moulin, P., Boiret, M., Cinier, R., Despagne, F., Dubost, J.-P., Frances, L., Le Page, M., Michelet, A., & Ziemons, E. (03 October 2013). Dosages quantitaifs de principes actifs dans les formes solides par spectroscopie proche infrarouge: Application pratique au test d'uniformité de teneur des comprimés. Paper presented at Session d'études SFSTP, Paris, France.

Ziemons, E., De Bleye, C., Chavez, P.-F., Netchacovitch, L., Sacre, P.-Y., Rozet, E., Lebrun, P., & Hubert, P. (10 September 2013). Vibrational spectroscopy as PAT compliant tools. Paper presented at Chemical Manufacturing and Control (CMC) Seminar, Diepenbeek, Belgium.

Chavez, P.-F., Netchacovitch, L., Sacre, P.-Y., De Bleye, C., Lebrun, P., Motte, H., Evrard, B., Hubert, P., & Ziemons, E. (September 2013). Application of a Design Space Approach for a Pharmaceutical Tablet Formulation Optimization based on a Mixture Design of Experiments and using Vibrational Spectroscopy as PAT Tool. Poster session presented at EuPAT 6 - Sixth pan-European QbD & PAT Science Conference, Porto, Portugal.

Dispas, A., Ziemons, E., & Hubert, P. (2013). Chimie Analytique - Manuel de Travaux Pratiques. (ULiège - Université de Liège, CHIM0330-3 Chimie Analytique (partim 1)).

Sacre, P.-Y., Lebrun, P., Chavez, P.-F., De Bleye, C., Netchacovitch, L., Rozet, E., Hubert, P., & Ziemons, E. (September 2013). A new criterion to assess distributional homogeneity in hyperspectral images of solid pharmaceutical dosage forms. Paper presented at EuPAT 6 (Sixth pan-European QbD & PAT Science Conference), Porto, Portugal.

Ziemons, E., Moonen, F., & Hubert, P. (23 July 2013). Analyzing spectral data for the selection of a calibration model.

De Bleye, C., Sacre, P.-Y., Chavez, P.-F., Netchacovitch, L., Dumont, E., Rozet, E., Piel, G., Hubert, P., & Ziemons, E. (July 2013). Chemical imaging of small molecules from simple to complex matrices: Quantitative approaches based on Surface Enhanced Raman scattering. Paper presented at Symposium on Pharmaceutical and Biomedical Analysis 2013 (PBA 2013), Bologna, Italy.

Hubert, C., Lebrun, P., Houari, S., Dispas, A., Rozet, E., Ziemons, E., & Hubert, P. (July 2013). Innovative strategy based on the quality by design concept for the development of a LC/MS method. Poster session presented at 24th Symposium on Pharmaceutical and Biomedical Analysis, Bologna, Italy.

Chavez, P.-F., Netchacovitch, L., Sacre, P.-Y., De Bleye, C., Pestieau, A., Krier, F., Mantanus, J., Motte, H., Schubert, M., Evrard, B., Hubert, P., & Ziemons, E. (June 2013). Optimization of a Pharmaceutical Tablet Formulation: Screening Experiments using Vibrational Spectroscopy as PAT Tool. Poster session presented at 2013 AAPS Annual Meeting and Exposition, San Antonio, United States - Texas.

Dispas, A., Lebrun, P., Rozet, E., Ziemons, E., Vial, J., Thiébaut, D., & Hubert, P. (June 2013). Optimisation robuste de méthodes SFC par une approche de type design space. Paper presented at 10e congrès francophone de l'Afsep sur les sciences séparatives et les couplages, Paris, France.

Hubert, C., Lebrun, P., Houari, S., Dispas, A., Rozet, E., Ziemons, E., & Hubert, P. (June 2013). Innovative strategy based on the quality by design concept for the development of a LC/MS method. Poster session presented at 10ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Paris, France.

Chavez, P.-F., Sacre, P.-Y., De Bleye, C., Netchacovitch, L., Motte, H., Hubert, P., & Ziemons, E. (June 2013). Qualitative Approaches to Monitor Pharmaceutical Blending Processes using In-line Near-Infrared Spectroscopy. Poster session presented at 24th Symposium on Pharmaceutical and Biomedical Analysis (PBA2013), Bologna, Italy.

De Bleye, C., Dumont, E., Chavez, P.-F., Netchacovitch, L., Piel, G., Rozet, E., Sacre, P.-Y., Hubert, P., & Ziemons, E. (18 April 2013). Development of quantitative approaches based on Surface Enhanced Raman Scattering chemical imaging. Poster session presented at The bioforum 2013 of BioLiège, Liège, Belgium.

Chavez, P.-F., De Bleye, C., Sacre, P.-Y., Rozet, E., Hubert, P., & Ziemons, E. (February 2013). Validation methodologies of near infrared spectroscopy methods in pharmaceutical applications. European Pharmaceutical Review, 18 (1), 3-6.

Rozet, E., Ziemons, E., Marini Djang'Eing'A, R., Boulanger, B., & Hubert, P. (2013). Methodology for the Validation of Analytical Methods involved in Uniformity of Dosage Units tests. Analytica Chimica Acta, 760, 46-52. doi:10.1016/j.aca.2012.11.013
Peer Reviewed verified by ORBi

Rozet, E., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (2013). Usefulness of Information Criteria for the Selection of Calibration Curves. Analytical Chemistry, 85, 6327-6335. doi:10.1021/ac400630k
Peer Reviewed verified by ORBi

Krier, F., Mantanus, J., Sacre, P.-Y., Chavez, P.-F., Thiry, J., Pestieau, A., Rozet, E., Ziemons, E., Hubert, P., & Evrard, B. (2013). PAT tools for the control of co-extrusion implants manufacturing process. International Journal of Pharmaceutics, 458, 15-24. doi:10.1016/j.ijpharm.2013.09.040
Peer Reviewed verified by ORBi

Michelet, A., Boiret, M., Lemhachheche, F., Malec, L., Tfayli, A., & Ziemons, E. (2013). Use of Raman spectrometry in the pharmaceutical field. STP Pharma Pratiques, 23 (2), 97-117.

Tiuca, I., Saponar, A., Bodoki, A., Ziemons, E., Bodoki, E., Hubert, P., & Oprean, R. (2013). ATR-IR and Raman spectroscopic study of interaction between major calixarene derivatives and oral anticoagulants. Farmacia, 61 (5), 874-882.
Peer reviewed

Sacre, P.-Y., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2012). Intérêt de la microscopie vibrationnelle dans la recherche de nouvelles formulations pharma-ceutiques à haute valeur ajoutée. (Rapport d'activité de 12 mois, -). Liège, Belgium: ULg.

Krier, F., mantanus, J., Ziemons, E., Hubert, P., & Evrard, B. (16 October 2012). Comparison of in-line active content determination of polymeric implant by near infrared spectroscopy and Raman spectroscopy. Poster session presented at Congrés annuel de l'AAPS2012.

Ziemons, E., Ceccato, A., & Hubert, P. (2012). Content uniformity determination in silicone-based drug reservoirs by near infrared spectroscopy.

Dispas, A., Lebrun, P., Sassiat, P., Ziemons, E., Thiébaut, D., Vial, J., & Hubert, P. (September 2012). Innovative green supercritical fluid chromatography development for the determination of polar compounds. Journal of Chromatography. A, 1256, 253-260. doi:10.1016/j.chroma.2012.07.043
Peer Reviewed verified by ORBi

Chavez, P.-F., Hubert, P., & Ziemons, E. (2012). Pharmaceutical tablet: Improvement on API content uniformity. ULg - Université de Liège.

Hubert, C., Lebrun, P., Houari, S., Bakima, P., Rozet, E., Ziemons, E., & Hubert, P. (20 June 2012). First Application of an Innovative Design Space Optimization Strategy for the Development of a LC/MS Method. Poster session presented at 38th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Anaheim, United States - California.

Ziemons, E., De Bleye, C., Chavez, P.-F., Rozet, E., Lebrun, P., & Hubert, P. (10 May 2012). Development of near infrared spectroscopic methods using desirability indexes: How to select the most appropriate calibration model. Paper presented at EuPAT 5 - Fith pan-European QbD & PAT Science Conference, Ghent, Belgium.

Chavez, P.-F., Mantanus, J., Cuypers, S., Hubert, P., Ziemons, E., & Motte, H. (May 2012). Use of Near Infrared and Raman spectroscopy for the optimization of API layer of pharmaceutical tablet. Poster session presented at BPS Science Day, Braine-l'Alleud, Belgium.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkerberg, R., Streel, B., Evrard, B., & Hubert, P. (March 2012). AN INNOVATIVE APPROACH TO SELECT THE PREDICTION MODEL IN THE DEVELOPMENT OF NIR SPECTROSCOPIC METHODS. Poster session presented at AGROSTAT 2012, Paris, France.

Rozet, E., Boulanger, B., Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (March 2012). SMALL SAMPLE SIZE CAPABILITY INDEX FOR ASSESSING VALIDITY OF ANALYTICAL METHODS. Poster session presented at AGROSTAT 2012, Paris, France.

Rozet, E., Govaerts, B., Lebrun, P., Boulanger, B., Ziemons, E., & Hubert, P. (March 2012). RELIABILITY OF ANALYTICAL METHODS’ RESULTS: A BAYESIAN APPROACH TO ANALYTICAL METHOD VALIDATION. Paper presented at AGROSTAT 2012, Paris, France.

Rozet, E., Ziemons, E., Marini Djang'Eing'A, R., Boulanger, B., & Hubert, P. (2012). Validation of analytical methods involved in dissolution assays: Acceptance limits and decision methodologies. Analytica Chimica Acta, 751, 44-51. doi:10.1016/j.aca.2012.09.017
Peer Reviewed verified by ORBi

Rozet, E., Ziemons, E., Marini Djang'Eing'A, R., Boulanger, B., & Hubert, P. (2012). Reply to the responses on the comments on “Uncertainty profiles for the validation of analytical methods” by Saffaj and Ihssane. Talanta, 100, 290-292. doi:10.1016/j.talanta.2012.07.047
Peer Reviewed verified by ORBi

Bouabidi, A., Ziemons, E., Marini Djang'Eing'A, R., Hubert, C., Talbi, M., Bourichi, H., El Karbane, M., Boulanger, B., Hubert, P., & Rozet, E. (2012). Usefulness of capability indices in the framework of analytical methods validation. Analytica Chimica Acta, 714, 47-56. doi:10.1016/j.aca.2011.11.019
Peer Reviewed verified by ORBi

Rozet, E., Ziemons, E., Marini Djang'Eing'A, R., Boulanger, B., & Hubert, P. (January 2012). Comments on “Uncertainty profiles for the validation of analytical methods” by Saffaj and Ihssane [letter to the editor]. Talanta, 88, 769-771. doi:10.1016/j.talanta.2011.11.011
Peer Reviewed verified by ORBi

De Bleye, C., Chavez, P.-F., Mantanus, J., Marini Djang'Eing'A, R., Hubert, P., Rozet, E., & Ziemons, E. (2012). Critical Review of Near-Infrared Spectroscopic Methods Validations in Pharmaceutical Applications. Journal of Pharmaceutical and Biomedical Analysis, 69, 125-132. doi:10.1016/j.jpba.2012.02.003
Peer Reviewed verified by ORBi

Rozet, E., Ziemons, E., Marini Djang'Eing'A, R., Boulanger, B., & Hubert, P. (2012). Quality by design compliant analytical method validation. Analytical Chemistry, 84, 106-112. doi:10.1021/ac202664s
Peer Reviewed verified by ORBi

Krier, F., Mantanus, J., Ziemons, E., & Evrard, B. (October 2011). In-line active content determination of polymeric implant by near infrared spectroscopy. Poster session presented at AAPS Annual Meeting and Exposition, Washington, United States.

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (October 2011). Silicone-based drug reservoirs manufacturing process - Critical quality attributes evaluation using NIR and Raman spectroscopy. Poster session presented at AAPS Annual Meeting and Exposition, Washington, United States.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Lamalle, C., Fillet, M., Rudaz, S., & Hubert, P. (September 2011). IMPLEMENTATION OF GENERIC ANALYTICAL METHODS TO FIGHT AGAINST COUNTERFEIT MEDICINES. Paper presented at Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Rozet, E., Marini Djang'Eing'A, R., Lebrun, P., Ziemons, E., Boulanger, B., & Hubert, P. (September 2011). A BAYESIAN PREDICTIVE PROBABILITY CRITERION TO ASSESS ANALYTICAL METHODS VALIDITY. Poster session presented at Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

De Bleye, C., Mantanus, J., Rozet, E., Van Butsele, K., Marini Djang'Eing'A, R., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (September 2011). BUILDING THE QUALITY INTO THE POLYMERIC SOLID DOSAGE FORM MANUFACTURING LINE - CRITICAL QUALITY ATTRIBUTES EVALUATION WITH NIR AND RAMAN PAT TOOLS. Poster session presented at Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

Hubert, C., Ziemons, E., & Hubert, P. (2011). LCA-GE-005- Rapport de validation - VR001_V01.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Krier, F., Evrard, B., & Hubert, P. (June 2011). La spectroscopie vibrationnelle, outil indispensable pour l'industrie pharmaceutique ?

Hubert, C., Ziemons, E., & Hubert, P. (2011). Protocole d'essai LC/MS - P001 - V01.

Mantanus, J., Rozet, E., Lebrun, P., Evrard, B., Hubert, P., & Ziemons, E. (19 May 2011). Une solution analytique verte pour le PAT: la spectroscopie proche infrarouge. Paper presented at Chimie analytique verte: chromatographie en phase supercritique, liquides ioniques, haute température et miniaturisation, Paris, France.

Hubert, C., Ziemons, E., & Hubert, P. (2011). Qualitative analysis of potentials compounds contained in an aged matrix of a pharmaceutical speciality at the RT of an impurity.

Hubert, C., Ziemons, E., & Hubert, P. (2011). Rapport de validation LC/MS - PVR-001 - V02.

Ziemons, E., Frederich, M., Fillet, M., Hubert, P., & Quetin-Leclercq, J. (May 2011). Espectroscopia aplicada. Paper presented at Maestra en Ciencia y Tecnologia de Productos Naturales, Cochabamba, Bolivia.

Hubert, C., Ziemons, E., & Hubert, P. (2011). Comparison between new and old excipients.

Ziemons, E., Rozet, E., & Hubert, P. (2011). Développement d'une méthodologie statistique basée sur l'intervalle de tolérance pour la sélection et l'évaluation de modèles robustes dans le domaine de la spectroscopie et de l'imagerie proche infrarouge. (Evaluation ex-post).

Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2011). Contrôle qualité. 15e Jour du Mois.

Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2011). Le fléau des faux médicaments. Eprint/Working paper retrieved from https://orbi.uliege.be/2268/84930.

Mantanus, J., Rozet, E., Van Butsele, K., De Bleye, C., Ceccato, A., Evrard, B., Hubert, P., & Ziemons, E. (2011). Near infrared and Raman spectroscopy as Process Analytical Technology tools for the manufacturing of silicone-based drug reservoirs. Analytica Chimica Acta, 699, 96-106. doi:10.1016/j.aca.2011.05.006
Peer Reviewed verified by ORBi

Rozet, E., Govaerts, B., Lebrun, P., Michail, K., Ziemons, E., Wintersteiger, R., Rudaz, S., Boulanger, B., & Hubert, P. (2011). Evaluating the reliability of analytical results using a probability criterion: a Bayesian perspective. Analytica Chimica Acta, 705, 193-206. doi:10.1016/j.aca.2011.05.028
Peer Reviewed verified by ORBi

Rozet, E., Marini Djang'Eing'A, R., Ziemons, E., Boulanger, B., & Hubert, P. (2011). Advances in validation, risk and uncertainty assessment of bioanalytical methods. Journal of Pharmaceutical and Biomedical Analysis, 55, 848-858. doi:10.1016/j.jpba.2010.12.018
Peer Reviewed verified by ORBi

Bouabidi, A., Talbi, M., Bouklouze, A., El Karbane, M., Bourichi, H., El Guezzar, M., Ziemons, E., Hubert, P., & Rozet, E. (2011). DO PLACEBO BASED VALIDATION STANDARDS MIMIC REAL BATCH PRODUCTS BEHAVIOUR? CASE STUDIES. Journal of Pharmaceutical and Biomedical Analysis, 55, 583-590. doi:10.1016/j.jpba.2011.02.008
Peer Reviewed verified by ORBi

Ziemons, E., Bourichi, H., Mantanus, J., Rozet, E., Lebrun, P., Essassi, E., Cherrah, Y., Bouklouze, A., & Hubert, P. (2011). Determination of binary polymorphic mixtures of fluconazole using near infrared spectroscopy and X-ray powder diffraction: A comparative study based on the pre-validation stage results. Journal of Pharmaceutical and Biomedical Analysis, 55, 1208-1212. doi:10.1016/j.jpba.2011.02.019
Peer Reviewed verified by ORBi

Krier, F., Brion, M., Debrus, B., Lebrun, P., Driesen, A., Ziemons, E., Evrard, B., & Hubert, P. (2011). Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities. Journal of Pharmaceutical and Biomedical Analysis, 54, 694-700. doi:10.1016/j.jpba.2010.10.022
Peer Reviewed verified by ORBi

Rozet, E., Rudaz, S., Marini Djang'Eing'A, R., Ziemons, E., Boulanger, B., & Hubert, P. (2011). Models to estimate overall analytical measurements uncertainty: assumptions, comparisons and applications. Analytica Chimica Acta, 702, 160-171. doi:10.1016/j.aca.2011.06.055
Peer Reviewed verified by ORBi

Rozet, E., Dewe, W., Rudaz, S., Marini Djang'Eing'A, R., Ziemons, E., Boulanger, B., & Hubert, P. (2011). Total Error and Uncertainty: Friends or Foes? TrAC: Trends in Analytical Chemistry, 30 (5), 797-806. doi:10.1016/j.trac.2010.12.009
Peer Reviewed verified by ORBi

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Moonen, F., Evrard, B., & Hubert, P. (08 December 2010). Vibrational spectroscopy in pharmaceutical industry: From development of the most appropriate predictive model to routine implementation. Poster session presented at BioWin Day 2010, Louvain-la-Neuve, Belgium.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Evrard, B., Moonen, F., & Hubert, P. (02 December 2010). Use of tolerance intervals in the development of near infrared spectroscopic methods: An innovative way to select the most appropriate calibration model. Poster session presented at Chimiométrie 2010, Paris, France.

Rozet, E., Lebrun, P., Boulanger, B., Ziemons, E., & Hubert, P. (02 December 2010). Evaluating analytical results reliability using a Bayesian probability criterion. Poster session presented at Congrès Chimimétrie 2010, Paris, France.

Ziemons, E., & Hubert, P. (2010). Introduction à la spectroscopie Raman. (ULiège - Université de Liège, CHIM0330-1 - Chimie Analytique (Partim I)).

Ziemons, E., Sacre, P.-Y., & Hubert, P. (2010). Spectroscopie vibrationnelle dans le cadre du PAT - Des aspects qualitatifs à la quantification en ligne. (ULiège - Université de Liège, PHIN2022-1 Production industrielle des formes pharmaceutiques).

Ziemons, E., Rozet, E., & Hubert, P. (2010). Développement d'une méthodologie statistique basée sur l'intervalle de tolérance pour la sélection et l'évaluation de modèles robustes dans le domaine de la spectroscopie et de l'imagerie proche infrarouge. (4eme semestre).

Krier, F., Brion, M., Debrus, B., Lebrun, P., Driesen, A., Ziemons, E., Evrard, B., & Hubert, P. (15 November 2010). Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities. Poster session presented at The FIP Pharmaceutical Sciences World Congress 2010 in association with the AAPS Annual Meeting & Exposition, new orléans, United States.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (15 November 2010). NIR monitoring of solid and liquid forms manufacturing – Development and validation of in-line quantitative methods. Poster session presented at FIP Pharmaceutical Sciences 2010 world congress, New Orleans, United States.

Boulanger, B., Govaerts, B., Le Boulengé, E., Lebrun, P., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2010). Plans expérimentaux. (ULiège - Université de Liège).

Tiuca, I., Mantanus, J., Iacob, B., Ede, B., Oprean, R., Hubert, P., & Ziemons, E. (November 2010). Raman spectroscopic study of complex formation between major calixarene derivatives and three pharmaceutical substances. Poster session presented at Jours de l’Université de Médecine et Pharmacie „Iuliu Haţieganu”, Cluj-Napoca, Romania.

Hubert, C., Ziemons, E., & Hubert, P. (2010). Report of the development of a LC-MS method for the assay of an impurity in a pharmaceutical speciality.

Mantanus, J., Lebrun, P., Rozet, E., Evrard, B., Hubert, P., & Ziemons, E. (14 October 2010). La spectroscopie proche infrarouge et Raman: Nouvelles armes vertes dans le contrôle de la qualité du médicament. Poster session presented at Journée Scientifique Annuelle de la Société Royale de Chimie: Chimie Verte, Gembloux, Belgium.

Hubert, P., Ziemons, E., Mantanus, J., Lebrun, P., Boulanger, B., & Rozet, E. (October 2010). RISK MANAGMENT IN THE VALIDATION OF ANALYTICAL METHODS. Paper presented at CNFR 2010 Congress, Targu-Mures, Romania.

Rozet, E., Lebrun, P., Boulanger, B., Ziemons, E., & Hubert, P. (October 2010). Analytical results reliability using a probability criterion: a Bayesian perspective. Poster session presented at Chemometrics in Analytical Chemistry, Antwerpen, Belgium.

Mantanus, J., Ziemons, E., Van Butsele, K., Evrard, B., Ceccato, A., & Hubert, P. (24 September 2010). NIR AND RAMAN SPECTROSCOPY AS PAT TOOLS FOR THE MANUFACTURING OF SILICONE-BASED DRUG RESERVOIRS. Paper presented at Drug Analysis 2010, Anvers, Belgium.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Montes, M. L. A., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Rudaz, S., & Hubert, P. (September 2010). Contribution to fight against counterfeit medecines applying several analytical tools. Poster session presented at International Symposium on Drug Analysis 2010, Anvers, Belgium.

Bouabidi, A., Talbi, M., Bouklouze, A., Ziemons, E., Rozet, E., & Hubert, P. (September 2010). Does placebo based validation standards mimic well real batch products behaviour? A case study. Poster session presented at Drug Analysis 2010, Antwerpen, Belgium.

Rozet, E., Boulanger, B., Dewe, Ziemons, E., Marini Djang'Eing'A, R., & Hubert, P. (September 2010). Total error as natural decision criteria for analytical methods validation and transfer. Paper presented at Drug Analysis 2010, Antwerpen, Belgium.

Ziemons, E., Mantanus, J., Rozet, E., Lebrun, P., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (September 2010). An innovative approach to select the prediction model in the development of NIR spectroscopy methods. Poster session presented at Drug Analysis, Antwerpen, Belgium.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Montes, M. L. A., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Rohrbasser, C., Rudaz, S., & Hubert, P. (September 2010). Analytical tools to fight against counterfeit medicines. Chimica Oggi, 28 (5), 10-14.
Peer Reviewed verified by ORBi

Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2010). Nettoyage des équipements et validation de nettoyage. (ULiège - Université de Liège).

Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2010). Out Of Specification ou Non-Conformité. (ULiège - Université de Liège).

Marini Djang'Eing'A, R., Mbinze Kindende, J., Lecomte, F., Debrus, B., Lebrun, P., Rozet, E., Mantanus, J., Ziemons, E., & Hubert, P. (31 July 2010). La contrefaçon des médicaments : outils pour lutter contre ce fléau. Paper presented at Conférence Scientifique, Kisangani, Province Orientale, Congo - Kinshasa.

Ziemons, E., Rozet, E., & Hubert, P. (2010). Développement d'une méthodologie statistique basée sur l'intervalle de tolérance pour la sélection et l'évaluation de modèles robustes dans le domaine de la spectroscopie et de l'imagerie proche infrarouge. (3eme semestre).

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (05 May 2010). NIR as a PAT tool for solid and liquid forms manufacturing - Development and validation of in-line quantitative methods. Poster session presented at 4th Pan European Pat Science conference, Kuopio, Finland.

Mantanus, J., Ziemons, E., Evrard, B., Van Butsele, K., Ceccato, A., & Hubert, P. (05 May 2010). NIR Real-time monitoring of a silicone-based drug reservoir crosslinking process. Poster session presented at 4th Pan European Pat Science conference, Kuopio, Finland.

Ziemons, E., Ceccato, A., & Hubert, P. (2010). Utilisation de la spectroscopie proche infrarouge dans la cadre de la fabrication d'un dispositif intra-utérin. (3eme semestre & Final).

Ginot, Y. M., Bernard-Moulin, P., Cinier, R., Despagne, F., Dubost, J. P., Francès, L., Le Bihan, M., Le Page, M., Michelet, A., Meunieur, L., Monteillet, G., Quintana, A., Rieutord, A., Storme, I., Thenevot, F., & Ziemons, E. (April 2010). Quantitative analysis using near infrared spectroscopy, Application to tablet content uniformity, I. Methodology. STP Pharma Pratiques, 20 (2), 117-135.

Marini Djang'Eing'A, R., Rozet, E., Hubert, C., Ziemons, E., & Hubert, P. (March 2010). Estimation of uncertainty from the total error strategy: Application to internal and normative methods. Acta Clinica Belgica, 65, 100-104.
Peer Reviewed verified by ORBi

Ziemons, E., Mantanus, J., Lebrun, P., Rozet, E., Evrard, B., & Hubert, P. (2010). Acetaminophen determination in low-dose pharmaceutical syrup by NIR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis, 53, 510-516. doi:10.1016/j.jpba.2010.06.003
Peer Reviewed verified by ORBi

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2010). Active content determination of non-coated pharmaceutical pellets by near infrared spectroscopy: Method development, validation and reliability evaluation. Talanta, 80, 1750-1757. doi:10.1016/j.talanta.2009.10.019
Peer Reviewed verified by ORBi

Hubert, C., Ziemons, E., Rozet, E., Breuer, A., Lambert, A., Jasselette, C., De Bleye, C., Lejeune, R., & Hubert, P. (January 2010). Development and validation of a quantitative method for the selective determination of tin species in tin octoate by differential pulse polarography. Talanta, 80 (3), 1413-1420. doi:10.1016/j.talanta.2009.09.045
Peer Reviewed verified by ORBi

Mantanus, J., Ziemons, E., Rozet, E., Streel, B., Klinkenberg, R., Evrard, B., Rantanen, J., & Hubert, P. (2010). Building the quality into pellet manufacturing environment - feasibility study and validation of an in-line quantitative near infrared (NIR) method. Talanta, 83, 305-311. doi:10.1016/j.talanta.2010.09.009
Peer Reviewed verified by ORBi

Rozet, E., Bouabidi, A., Fillet, M., Ziemons, E., Chapuzet, E., Mertens, B., Klinkenberg, R., Ceccato, A., Talbi, M., Streel, B., Bouklouze, A., Boulanger, B., & Hubert, P. (2010). Critical analysis of several analytical method validation strategies in the framework of the fit for purpose concept. Journal of Chromatography. A, 1217, 3180-3192. doi:10.1016/j.chroma.2009.08.051
Peer Reviewed verified by ORBi

Ziemons, E., & Hubert, P. (2010). Activités de recherche du laboratoire de Chimie Analytique. Paper presented at Forum des Seniors, Liège, Belgium.

Fotsing, L., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2010). Audits de qualités des fournisseurs de produits pharmaceutiques: Aspects théoriques et pratiques. (ULiège - Université de Liège).

Bonnard, E., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2010). Bonnes Pratiques de Fabrication - Good Manufacturing Practice. (ULiège - Université de Liège).

Ziemons, E., Sacre, P.-Y., Evrard, B., & Hubert, P. (2010). Process Analytical Technology (PAT) - Technologie de contrôle des Procédés. (ULiège - Université de Liège, PHIN2022-1 Production industrielle des formes pharmaceutiques).

Ziemons, E., Moonen, F., & Hubert, P. (03 December 2009). Analysing spectral data for the selection of a calibration model.

Ziemons, E., Rozet, E., & Hubert, P. (2009). Développement d'une méthodologie statistique basée sur l'intervalle de tolérance pour la sélection et l'évaluation de modèles robustes dans le domaine de la spectroscopie et de l'imagerie proche infrarouge. (2ème semestre).

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (November 2009). Active content determination of non-coated pharmaceutical pellets by near infrared spectroscopy: Method development, validation and reliability evaluation. Poster session presented at Annual Meeting and Exposition of the American Association of Pharmaceutical Scientists, Los Angeles, United States.

Hubert, C., Ziemons, E., & Hubert, P. (2009). Rapport final de développement et de validation de l'étain dans l'octanoate d'étain.

Marini Djang'Eing'A, R., Rozet, E., Hubert, C., Ziemons, E., & Hubert, P. (October 2009). Estimation de l’incertitude à partir de la stratégie de l’erreur totale : Application pour des méthodes internes et des méthodes normatives. Poster session presented at 4ème journées internationales de Toxicologie, Liège, Belgium.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Rudaz, S., Klinkenberg, R., Streel, B., & Hubert, P. (September 2009). Validation of a near infrared spectroscopy method for the quantitative determination of an active ingredient in non-coated pharmaceutical pellets. Poster session presented at 13th International Meeting of Recent Developments in Pharmaceutical Analysis, Milan, Italy.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (September 2009). Production line real time near infrared (NIR) monitoring. Paper presented at 3rd Annual Pharmaceutical Solid State Research Cluster Symposium, Copenhagen, Denmark.

Hubert, P., Ziemons, E., & Rozet, E. (2009). Validation des méthodes d'analyse pharmaceutique et biopharmaceutique. (ULiège - Université de Liège, PHAR0713-A-a).

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (August 2009). Quantitative in-line monitoring of pharmaceutical pellets active content using near infrared spectroscopy. Poster session presented at 3rd Annual Pharmaceutical Solid State Research Cluster Symposium, Copenhagen, Denmark.

Mantanus, J., Ziemons, E., Streel, B., Klinkenberg, R., Evrard, B., Hubert, P., & Rantanen, J. (June 2009). Interfacing near infrared (NIR) spectroscopy with production line - Role of sample movement and density. Poster session presented at Premier European Platform for Advancing Pharmaceutical Sciences, Nice, France.

Ziemons, E., Rozet, E., & Hubert, P. (2009). Développement d'une méthodologie statistique basée sur l'intervalle de tolérance pour la sélection et l'évaluation de modèles robustes dans le domaine de la spectroscopie et de l'imagerie proche infrarouge. (1er semestre).

Ziemons, E., Ceccato, A., & Hubert, P. (2009). Utilisation de la spectroscopie proche infrarouge dans la cadre de la fabrication d'un dispositif intra-utérin. (2ème semestre).

Hubert, C., Ziemons, E., & Hubert, P. (2009). Développement et validation d'une méthode de dosage de la glucosamine dans le plasma cannin par SPE/LC/MS.

Mantanus, J., Ziemons, E., & Hubert, P. (2009). Etablissement d'interfaces proche infrarouge adaptées à la nature du mouvement des pellets pharmaceutiques. (1).

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2009). Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: method development and validation. Analytica Chimica Acta, 642 (1-2), 186-92. doi:10.1016/j.aca.2008.12.031
Peer Reviewed verified by ORBi

Rozet, E., Fillet, M., Bouabidi, A., Ziemons, E., Talbi, M., Bouklouze, A., Boulanger, B., & Hubert, P. (2009). Critical analysis of several analytical method validation strategies in the framework of the fit for purpose concept. Poster session presented at HPLC.

Rozet, E., Boulanger, B., Marini Djang'Eing'A, R., Ziemons, E., Rudaz, S., & Hubert, P. (2009). Validation of bioanalytical methods using total error. Paper presented at 21st International Symposium on Pharmaceutical and Biomedical Analysis.

Rozet, E., Boulanger, B., Rudaz, S., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Total Error for the validation of bioanalytical methods. Paper presented at TIAFT - The International Association of Forensic Toxicologists.

Rozet, E., Boulanger, B., Rudaz S, Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Total Error for the Valildation of Bioanalytical methods. Annales de Toxicologie Analytique, 21 (S1), 35.
Peer Reviewed verified by ORBi

Rozet, E., Boulanger, B., Rudaz, S., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Universal applicability of Total Error for the validation of bioanalytical methods. Paper presented at 4èmes JOURNEES INTERNATIONALES de toxicologie, liege, Belgium.

Rozet, E., Mantanus, J., Ziemons, E., Boulanger, B., Dewe, W., Crommen, J., & Hubert, P. (2009). Practical Implementation of Total Error for the Validation of Chromatographic and Ligand Binding Assays. Paper presented at PharmSciFair.

Rozet, E., Dewé, W., Ziemons, E., Bouklouze, A., Boulanger, B., & Hubert, P. (2009). Methodologies for the transfer of analytical methods: A review. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877, 2214-2223. doi:10.1016/j.jchromb.2008.12.049
Peer Reviewed verified by ORBi

Ziemons, E., & Hubert, P. (2009). Good Laboratory Practice: How to avoid pitfalls of quantitative analysis. (ULiège - Université de Liège).

Ziemons, E., Rozet, E., & Hubert, P. (2008). Développement d'un logiciel basé sur l'intervalle de tolérance pour l'estimation de l'incertitude. (Questionnaire d'évaluation des projets de recherche).

Ziemons, E., Rozet, E., & Hubert, P. (2008). Développement d'un logiciel basé sur l'intervalle de tolérance pour l'estimation de l'incertitude. (4eme semestre).

Ziemons, E., Ceccato, A., & Hubert, P. (2008). Utilisation de la spectroscopie proche infrarouge dans la cadre de la fabrication d'un dispositif intra-utérin. (1er semestre).

Ziemons, E., Mantanus, J., & Hubert, P. (2008). Détermination de la teneur en eau et de principes actifs dans des formulations pharmaceutiques à base de pellets par spectroscopie dans le proche infrarouge. (2).

Ziemons, E., Bourichi, H., Mantanus, J., Lebrun, P., Bouklouze, A., Cherrah, Y., & Hubert, P. (October 2008). Analyse quantitative de mélanges binaires de deux formes cristallines du fluconazole par la spectroscopie proche infrarouge et par diffraction des rayons X: comparaison des deux méthodes. Paper presented at 2ème Congrès des Sciences Analytiques, Casablanca, Morocco.

Hubert, P., Habyalimana, V., Marini Djang'Eing'A, R., & Ziemons, E. (2008). Préparation des échantillons pharmaceutiques. (ULiège - Université de Liège, PHAR0713-A-a).

Ziemons, E., Rozet, E., & Hubert, P. (2008). Développement d'un logiciel basé sur l'intervalle de tolérance pour l'estimation de l'incertitude. (3eme semestre).

Ziemons, E., Mantanus, J., & Hubert, P. (2008). Détermination de la teneur en eau et de principes actifs dans des formulations pharmaceutiques à base de pellets par spectroscopie dans le proche infrarouge. (1).

Barillaro, V., Dive, G., Ziemons, E., Bertholet, P., Evrard, B., Delattre, L., & Piel, G. (10 February 2008). Theoretical and Experimental Vibrational Study of Miconazole and Its Dimers with Organic Acids: Application to the IR Characterization of Its Inclusion Complexes with Cyclodextrins. International Journal of Pharmaceutics, 350 (1-2), 155-165. doi:10.1016/j.ijpharm.2007.08.048
Peer Reviewed verified by ORBi

Barillaro, V., Dive, G., Bertholet, P., Evrard, B., Delattre, L., Frederich, M., Ziemons, E., & Piel, G. (22 January 2008). Theoretical and Experimental Investigations of Organic Acids/Cyclodextrin Complexes and Their Consequences Upon the Formation of Miconazole/Cyclodextrin/Acid Ternary Inclusion Complexes. International Journal of Pharmaceutics, 347 (1-2), 62-70. doi:10.1016/j.ijpharm.2007.06.030
Peer Reviewed verified by ORBi

Ginot, Y. M., Bernard-Moulin, P., Cinier, R., Despagne, F., Dubost, J. P., Francès, L., Le Bihan, M., Le Page, M., Michelet, A., Meunier, L., Monteillet, G., Quintana, A., Rieutord, A., Storme, I., Thenevot, F., & Ziemons, E. (2008). Analyse quantitative par spectroscopie proche infrarouge: Application au test d'unifomité de teneur des comprimés. Paper presented at Session d'étude SFSTP, Paris, France.

Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Hubert, C., Moonen, F., & Hubert, P. (2008). Simultaneous improvement of the predictive character of the validation data and estimation of measurement uncertainty. Paper presented at Agrostat, Louvain-la-Neuve, Belgium.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., Evrard, B., & Hubert, P. (2008). Determination of moisture content in pharmaceutical pellets using near infrared spectroscopy: Method development and validation. Paper presented at PAT Workshop, Gent, Belgium.

Mantanus, J., Ziemons, E., Lebrun, P., Rozet, E., Klinkenberg, R., Streel, B., & Hubert, P. (2008). Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: model selection, evaluation and validation. Poster session presented at 11th Conference on Chemometrics in Analytical Chemistry, Montpellier, France.

Ziemons, E., Lejeune, R., & Hubert, P. (2008). Supports visuels réalisés dans le cadre des travaux pratiques de Chimie Analytique (Partie II). (ULiège - Université de Liège, CHIM0321-2 - Travaux pratiques - Introduction à la Chimie Analytique).

Rozet, E., Dewé, W., Morello, R., Chiap, P., Lecomte, F., Ziemons, E., Boos, K. S., Boulanger, B., Crommen, J., & Hubert, P. (2008). Risk-Based Approach for the Transfer of Quantitative Methods: Bioanalytical Applications. Journal of Chromatography. A, 1189, 32-41. doi:10.1016/j.chroma.2007.11.029
Peer Reviewed verified by ORBi

Ziemons, E., Mantanus, J., Lebrun, P., Rozet, E., & Hubert, P. (2008). Reflexions, La Chimie Analytique Verte. (Planet'ULg, ULiège - Université de Liège). Reflexions.

Ziemons, E., Mantanus, J., & Hubert, P. (2008). PlanetULg, La Chimie Analytique Verte. (ULiège - Université de Liège).

Ziemons, E., Rozet, E., & Hubert, P. (2007). Développement d'un logiciel basé sur l'intervalle de tolérance pour l'estimation de l'incertitude. (2ème semestre).

Bodson, C., Rozet, E., Ziemons, E., Evrard, B., Hubert, P., & Delattre, L. (18 October 2007). Validation of manufacturing process of Diltiazem HCl tablets by NIR spectrophotometry (NIRS). Journal of Pharmaceutical and Biomedical Analysis, 45 (2), 356-361. doi:10.1016/j.jpba.2007.05.015
Peer Reviewed verified by ORBi

Rozet, E., Hubert, C., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (27 July 2007). Using tolerance intervals in pre-study validation of analytical methods to predict in-study results - The fit-for-future-purpose concept. Journal of Chromatography. A, 1158 (1-2), 126-137. doi:10.1016/j.chroma.2007.03.102
Peer Reviewed verified by ORBi

Ziemons, E., Rozet, E., & Hubert, P. (2007). Développement d'un logiciel basé sur l'intervalle de tolérance pour l'estimation de l'incertitude. (1 semestre).

Ziemons, E., Mbakop, N. W., Rozet, E., Lejeune, R., Angenot, L., Thunus, L., & Hubert, P. (April 2007). Optimisation of SFE method on-line coupled to FT-IR spectroscopy for the real-time monitoring of the extraction of tagitinin C in T-diversifolia. Journal of Supercritical Fluids, 40 (3), 368-375. doi:10.1016/j.supflu.2006.07.009
Peer Reviewed verified by ORBi

Ziemons, E., Rozet, E., Lejeune, R., Angenot, L., & Hubert, P. (20 March 2007). Dosage en ligne d'une molécule d'origine naturelle dans le CO2 supercritique à l'aide d'une cellule à haute pression équipée de fibres optiques couplant un spectrophotomère IRTF à un extracteur à fluide supercritique. Poster session presented at SEP 2007, Grenoble, France.

Hubert, C., Rozet, E., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (March 2007). Validation versus routine : Evaluation de l'aspect prédictif de l'intervalle de tolérance. Poster session presented at 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Grenoble, France.

Ziemons, E., Barillaro, V., Rozet, E., Mbakop, N. W., Lejeune, R., Angenot, L., Thunus, L., & Hubert, P. (15 February 2007). Direct determination of tagitinin C in Tithonia diversifolia leaves by on-line coupling of supercritical carbon dioxide extraction to FT-IR spectroscopy by means of optical fibres. Talanta, 71 (2), 911-917. doi:10.1016/j.talanta.2006.05.076
Peer Reviewed verified by ORBi

Ziemons, E., Dive, G., Debrus, B., Barillaro, V., Frederich, M., Lejeune, R., Angenot, L., Delattre, L., Thunus, L., & Hubert, P. (February 2007). Study of the physicochemical properties in aqueous medium and molecular modeling of tagitinin C/cyclodextrin complexes. Journal of Pharmaceutical and Biomedical Analysis, 43 (3), 910-919. doi:10.1016/j.jpba.2006.09.011
Peer Reviewed verified by ORBi

Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Marini Djang'Eing'A, R., Moonen, F., & Hubert, P. (2007). LA PREDICTION DES RISQUES ASSOCIES AUX DONNEES DU CYCLE DE VIE DES METHODES DE DOSAGE. Paper presented at VI Colloquium Chemometricum Mediterraneum.

Rozet, E., Dewe, W., Morello, R., Chiap, P., Ziemons, E., Boos, K. S., Boulanger, B., & Hubert, P. (2007). GESTION DU RISQUE LORS DU TRANSFERT DE METHODES ANALYTIQUES – CAS D’UNE METHODE BIOANALYTIQUE. Paper presented at SEP07.

Ziemons, E., & Hubert, P. (2007). La spectroscopie infrarouge (Mid-IR & NIR). (ULiège - Université de Liège, CHIM0330-1 - Chimie Analytique (Partim I)).

Barillaro, V., Dive, G., Bertholet, P., Evrard, B., Delattre, L., Ziemons, E., & Piel, G. (2007). Theoretical and experimental investigations on miconazole/cyclodextrin/acid complexes: Molecular modeling studies. International Journal of Pharmaceutics, 342 (1-2), 152-160. doi:10.1016/j.ijpharm.2007.05.003
Peer Reviewed verified by ORBi

Rozet, E., Ceccato, A., Hubert, C., Ziemons, E., Oprean, R., Rudaz, S., Boulanger, B., & Hubert, P. (2007). Analysis of recent pharmaceutical regulatory documents on analytical method validation. Journal of Chromatography. A, 1158 (1-2), 111-25. doi:10.1016/j.chroma.2007.03.111
Peer Reviewed verified by ORBi

Marini Djang'Eing'A, R., Rozet, E., Vanderheyden, Y., Ziemons, E., Boulanger, B., Bouklouze, A., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (2007). Robustness testing of a chiral NACE method for R-timolol determination in S-timolol maleate and uncertainty assessment from quantitative data. Journal of Pharmaceutical and Biomedical Analysis, 44 (3), 640-51. doi:10.1016/j.jpba.2006.08.018
Peer Reviewed verified by ORBi

Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Hubert, C., Marini Djang'Eing'A, R., Moonen, F., & Hubert, P. (2007). PREDICTION OF THE RISKS LINKED TO THE DATA GENERATED DURING THE LIFE CYCLE OF QUANTITATIVE ANALYTICAL METHODS. Paper presented at 13eme Forum des Sciences Pharmaceutiques, Spa, Belgium.

Ziemons, E., Houbart, V., Lejeune, R., & Hubert, P. (2007). Supports visuels réalisés dans le cadre des travaux pratiques de Chimie Analytique (Partie I). (ULiège - Université de Liège, CHIM0321-2 - Travaux pratiques - Introduction à la Chimie Analytique).

Ziemons, E., & Hubert, P. (2007). L'extraction de matrices solides. (ULiège - Université de Liège, CHIM0331-1 - Chimie Analytique (Partim II)).

Hubert, C., Ziemons, E., & Hubert, P. (2006). Val06-004 - Validation du dosage du LNG contenu dans les réservoirs du Levosert-20.

Ziemons, E. (2006). Etude en temps réel du processus d'extraction de la tagitinine C en fonction des caractéristiques physico-chimiques du CO2 supercritique à l'aide de fibres optiques couplant un spectrophotomètre IRTF à un extracteur à fluide supercritique. Unpublished doctoral thesis, ULiège - Université de Liège.
Jury: Thunus, L. (Promotor), Angenot, L. (Promotor), Delattre, L., Hubert, P., Lejeune, R., Dive, G., Tilquin, B., Thiebaut, D., & Frederich, M.

Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS. Paper presented at A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium.

Hubert, C., Lambert, A., Ziemons, E., Hubert, P., & Lejeune, R. (May 2006). Speciation analysis of Sn(II) and Sn(IV) in stannous octoate using differential pulse polarography. Poster session presented at Drug Analysis 2006, Namur, Belgium.

Rozet, E., Ziemons, E., Eppe, G., Dewe, W., Boulanger, B., & Hubert, P. (2006). SIMULTANEOUS ESTIMATION OF MEASUREMENT UNCERTAINTY AND IMPLEMENTATION OF CONTROL CHART USING QUALITY CONTROL STANDARDS. Poster session presented at Drug Analysis.

Ziemons, E., Lejeune, R., Angenot, L., Thunus, L., & Hubert, P. (2006). Etude en temps réel du processus d'extraction de la tagitinine C en fonction des caractéristiques physico-chimiques du CO2 supercritique à l'aide de fibres optiques couplant un spectrophotomètre IRTF à un extracteur à fluide supercritique. Poster session presented at Forum Labo & Forum Biotech, Paris, France.

Ziemons, E., Barillaro, V., Rozet, E., Wandij Mbakop, N., Lejeune, R., Angenot, L., Thunus, L., & Hubert, P. (2006). Use of the accuracy profile for the validation of a direct determination of tagitinin C in Tithonia diversifolia leaves by on-line coupling of supercritical CO2 extraction to FT-IR spectroscopy by means of optical fibres. Poster session presented at Drug Analysis, Namur, Belgium.

Ziemons, E., Otte, X., Lejeune, R., Rozet, E., Thunus, L., & Hubert, P. (2005). Determination of fenofibrate, ciprofibrate and bezafibrate in mixtures by FTIR spectroscopy. Poster session presented at 11th meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy.

Ziemons, E., Goffin, E., Lejeune, R., Proença da Cunha, A. P., Angenot, L., & Thunus, L. (January 2005). Supercritical carbon dioxide extraction of tagitinin C from Tithonia diversifolia. Journal of Supercritical Fluids, 33 (1), 53-59. doi:10.1016/j.supflu.2004.04.001
Peer Reviewed verified by ORBi

Barillaro, V., Bertholet, P., Henry de Hassonville, S., Ziemons, E., Evrard, B., Delattre, L., & Piel, G. (30 November 2004). Effect of acidic ternary compounds on the formation of miconazole/cyclodextrin inclusion complexes by means of supercritical carbon dioxide. Journal of Pharmacy & Pharmaceutical Sciences : A Publication of the Canadian Society for Pharmaceutical Sciences, 7 (3), 378-388.
Peer reviewed

Ziemons, E., Goffin, E., Lejeune, R., Angenot, L., & Thunus, L. (06 February 2004). FT-IR measurement of tagitinin C after solvent extraction from Tithonia diversifolia. Talanta, 62 (2), 383-387. doi:10.1016/j.talanta.2003.08.007
Peer Reviewed verified by ORBi

Goffin, E., da Cunha, A. P., Ziemons, E., Tits, M., Angenot, L., & Frederich, M. (November 2003). Quantification of tagitinin C in Tithonia diversifolia by reversed-phase high-performance liquid chromatography. Phytochemical Analysis, 14 (6), 378-80. doi:10.1002/pca.732
Peer Reviewed verified by ORBi

Ziemons, E., Goffin, E., Lejeune, R., Angenot, L., & Thunus, L. (2003). Comparison of extraction yield and selectivity between supercritical fluid and classical methods of tagitinin C extraction. Paper presented at 11th Forum of Pharmaceutical Sciences, Spa, Belgium.

Ziemons, E., Goffin, E., Lejeune, R., Angenot, L., & Thunus, L. (2003). Supercritical fluid extraction of tagitinin C from Tithonia diversifolia: Comparison of extraction yield and selectivity between supercritical fluid and classical methods of extraction. Paper presented at 6th International Symposium on Supercritical fluids, Versailles, France.

Goffin, E., Ziemons, E., De Mol, P., de Madureira, M. D. C., Martins, A. P., da Cunha, A. P., Philippe, G., Tits, M., Angenot, L., & Frederich, M. (June 2002). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its main active constituent: tagitinin C. Planta Medica, 68 (6), 543-5. doi:10.1055/s-2002-32552
Peer Reviewed verified by ORBi

Ziemons, E. (2002). Extraction de lactones sesquiterpéniques par le CO2 supercritique et quantification de l'une d'elles: la tagitinine C par IRTF. Unpublished DEA/DES thesis, ULiège - Université de Liège.
Jury: Thunus, L. (Promotor), Delattre, L. (Promotor), Angenot, L. (Promotor), Lejeune, R. (Promotor), & Liégeois, J.-F. (Promotor).

Goffin, E., Frederich, M., Philippe, G., Ziemons, E., De Mol, P., Proença da Cunha, A., Tits, M., & Angenot, L. (September 2001). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its active constituent: tagitinin C. Poster session presented at Lead Compounds from Higher Plants, Lausanne, Switzerland.

Ziemons, E., Goffin, E., Angenot, L., & Thunus, L. (2001). Extraction of sesquiterpenic lactones with CO2 supercritical fluid and quantification of the extract by FTIR spectroscopy. Paper presented at 10th Forum of Pharmaceutical Sciences, Montréal, Canada.

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