Avohou, T. H. (2022). Bayesian one-class classification models: Application to pharmaceutical quality control using vibrational spectroscopy [Doctoral thesis, ULiège - University of Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/294487 |
Avohou, T. H., Sacre, P.-Y., Hamla, S., Lebrun, P., Hubert, P., & Ziemons, E. (05 September 2022). Optimizing the soft independent modeling of class analogy (SIMCA) using statistical prediction regions. Analytica Chimica Acta, 1229, 340339. doi:10.1016/j.aca.2022.340339 Peer Reviewed verified by ORBi |
Emonds-Alt, G., Malherbe, C., Kasemiire, A., Avohou, T. H., Hubert, P., Ziemons, E., Monbaliu, J.-C., & Eppe, G. (03 June 2022). Development and validation of an integrated microfluidic device with an in-line Surface Enhanced Raman Spectroscopy (SERS) detection of glyphosate in drinking water. Talanta, 249, 123640. doi:10.1016/j.talanta.2022.123640 Peer Reviewed verified by ORBi |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (04 March 2022). Interpretable One-Class Classification of Raman Spectra Using Prediction Bands Estimated by Wavelet Regression. Analytical Chemistry, 94, 4183-4191. doi:10.1021/acs.analchem.1c04098 Peer Reviewed verified by ORBi |
Sacre, P.-Y., Waffo Tchounga, C. A., Ciza Hamuli, P., Avohou, T. H., De Bleye, C., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (02 February 2022). Applications of vibrational spectroscopy and imaging for the analysis of substandard or falsified medicines [Paper presentation]. CIRM DAY. |
Sacre, P.-Y., Waffo Tchounga, C. A., Ciza Hamuli, P., Avohou, T. H., De Bleye, C., Hubert, P., Marini Djang'Eing'A, R., & Ziemons, E. (2022). Applications of vibrational spectroscopy and hyperspectral imaging for the analysis of substandard and falsified medicines [Paper presentation]. 12th International Symposium on Drug Analysis and the 32nd International Symposium on Pharmaceutical and Biomedical Analysis, Mons, Belgium. Peer reviewed |
Emonts, P., Avohou, T. H., Hubert, P., Ziemons, E., Fillet, M., & Dispas, A. (October 2021). Optimization of a robust and reliable FITC labeling process for CE-LIF analysis of pharmaceutical compounds using design of experiments strategy. Journal of Pharmaceutical and Biomedical Analysis, 205, 114304. doi:10.1016/j.jpba.2021.114304 Peer Reviewed verified by ORBi |
Emonts, P., Avohou, T. H., Hubert, P., Ziemons, E., Fillet, M., & Dispas, A. (October 2021). Development of a sensitive MEKC-LIF method for the analysis of synthetic cathinones and amphetamines Paul Emonts [Poster presentation]. SEP2021, Paris, France. |
Deidda, R., Avohou, T. H., Dumont, E., Hubert, C., Hubert, P., De Bleye, C., & Ziemons, E. (2021). Application of the analytical quality by design principles to the development of a qualitative surface-enhanced Raman scattering method: A proof of concept. Journal of Raman Spectroscopy. doi:10.1002/jrs.6249 Peer Reviewed verified by ORBi |
Kasemiire, A., Avohou, T. H., De Bleye, C., Sacre, P.-Y., Dumont, E., Hubert, P., & Ziemons, E. (11 June 2021). Design of experiments and design space approaches in the pharmaceutical bioprocess optimization. European Journal of Pharmaceutics and Biopharmaceutics, 166 (September), 144-154. doi:10.1016/j.ejpb.2021.06.004 Peer Reviewed verified by ORBi |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (03 February 2021). Using prediction bands for near-infrared spectra for authentication and verification of drug products [Paper presentation]. eChimiométrie 2021. |
Avohou, T. H., Sacre, P.-Y., Lebrun, P., Hubert, P., & Ziemons, E. (01 February 2021). A probabilistic class-modelling method based on prediction bands for functional spectral data: Methodological approach and application to near-infrared spectroscopy. Analytica Chimica Acta, 1144, 130-149. doi:10.1016/j.aca.2020.11.039 Peer Reviewed verified by ORBi |
NEEMA UFOYMUNGU, Y., JUAKALI SIHALIKYOLO, J. J., Marini Djang'Eing'A, R., KATENGA BOSUNGA, G., Avohou, T. H., LEDUC, S., BOEMER, F., & BATINA AGASA, S. (2020). Performance of Sickle SCAN® in the Screening of Sickle Cell Disease in Kisangani Pregnant Women and Attitude towards Results. Open Journal of Blood Diseases. doi:10.4236/ojbd.2020.102003 Peer reviewed |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (18 February 2020). A one-class Classification method based on depth statistics : applications to process analytical technology (PAT) and detection of counterfeited drugs [Paper presentation]. Weekly CIRM Scientific Seminar, Liege, Belgium. |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (28 January 2020). A probabilistic class-modelling method based on Bayesian prediction intervals for functional depth (vs outlyingness) statistics [Paper presentation]. Chimiométrie 2020, Liège, Belgium. |
Emonds-Alt, G., Avohou, T. H., Kasemiire, A., Malherbe, C., Monbaliu, J.-C., Ziemons, E., & Eppe, G. (28 January 2020). In-line monitoring of glyphosate in a microfluidic setup by SERS, development and optimization by DoE [Poster presentation]. Chimiométrie XXI, Liège, Belgium. |
Dispas, A., Emonts, P., Avohou, T. H., Ziemons, E., Hubert, P., & Fillet, M. (January 2020). Design of experiments approach to optimize FITC labeling process [Poster presentation]. Chimiométrie 2020, Liège, Belgium. |
Avohou, T. H., Lebrun, P., Rozet, E., & Boulanger, B. (2020). Bayesian methods in design and analysis of stability studies. In E. Lesaffre, G. Baio, ... B. Boulanger, Bayesian methods in pharmaceutical research (pp. 391-405). Boca Raton, United States: CRC Press. Peer reviewed |
Penoy, N., Avohou, T. H., Lebrun, P., Evrard, B., & Piel, G. (11 December 2019). A quality by design approach for liposomes production by innovative method using supercritical fluids: which parameters use to obtain good physicochemical characteristics? [Paper presentation]. Second CIRM Scientific Day, Liège, Belgium. |
Penoy, N., Avohou, T. H., Lebrun, P., Evrard, B., & Piel, G. (11 December 2019). A quality by design approach for liposomes production by innovative method using supercritical fluids: which parameters use to obtain good physicochemical characteristics? [Paper presentation]. Second CIRM Scientific Day, Liège, Belgium. |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (2019). Concept and prototype V4F for classification [Paper presentation]. Meeting for transfer of knowledge to Biion & Pharmalex, V4F, Mont Saint-Guilbert, Belgium. |
Avohou, T. H., Sacre, P.-Y., Lebrun, P., Hubert, P., & Ziemons, E. (15 November 2019). Class-modelling methods based on 𝜷-expectation tolerance regions for functional spectral (NIR and Raman) data [Paper presentation]. Scientific Workshops, Pharmalex, Mont Sain-Guilbert, Belgium. |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (24 October 2019). Spectrophotomètres portables :l’analyse chimique à portée de tous? [Paper presentation]. Liège Créative, Liege, Belgium. |
Avohou, T. H., Sacre, P.-Y., Hubert, P., & Ziemons, E. (2019). Logiciel Vibra4Fake 2020. |
Ciza Hamuli, P.* , Sacre, P.-Y.* , Waffo Tchounga, C., Coic, L., Avohou, T. H., Mbinze, J., Ngono, R., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (01 September 2019). Comparing the qualitative performances of handheld NIR and Raman spectrophotometers for the detection of falsified pharmaceutical products. Talanta, 202, 469-478. doi:10.1016/j.talanta.2019.04.049 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Emonds-Alt, G., Avohou, T. H., Kasemiire, A., Malherbe, C., Monbaliu, J.-C., Ziemons, E., & Eppe, G. (17 June 2019). Integrated microfluidic device for in-line monitoring of glyphosate assisted by Surface Enhanced Raman Spectroscopy [Paper presentation]. 17th International Conference on Chemistry and the Environment, Thessaloniki, Greece. |
Ciza Hamuli, P., Sacre, P.-Y., Waffo Tchounga, C. A., Coic, L., Avohou, T. H., mbinze, J., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (20 May 2019). Detection of falsified pharmaceutical products using Handheld NIR and Raman spectrophotometers [Paper presentation]. BSPS 2019 Forum of Pharmaceutical Sciences - May 20th 2019 - Brussels, Bruxelles, Belgium. |
Penoy, N., Bigazzi, W., Avohou, T. H., Lebrun, P., Evrard, B., & Piel, G. (20 May 2019). LIPOSOME PRODUCTION BY INNOVATIVE METHOD USING SUPERCRITICAL FLUIDS [Paper presentation]. 20th Forum of Pharmaceutical Sciences, Bruxelles, Belgium. |
Deidda, R., Avohou, T. H., Jambo, H., Dispas, A., Orlandini, S., Hubert, P., Ziemons, E., & Hubert, C. (20 May 2019). Principles of Analytical Quality by Design for the development of quality control methods in a pharmaceutical context [Paper presentation]. 20th Forum of Pharmaceutical Sciences - BSPS, Brussels, Belgium. |
Deidda, R.* , Sacre, P.-Y.* , Clavaud, M., Coic, L., Avohou, T. H., Hubert, P., & Ziemons, E. (May 2019). Vibrational spectroscopy in analysis of pharmaceuticals: Critical review of innovative portable and handheld NIR and Raman spectrophotometers. TrAC: Trends in Analytical Chemistry, 114, 251-259. doi:10.1016/j.trac.2019.02.035 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Deidda, R., Avohou, T. H., Kasemiire, A., Dumont, E., De Bleye, C., Hubert, P., Hubert, C., & Ziemons, E. (30 January 2019). Optimisation of a surface enhanced Raman scattering method using design of experiments and Bayesian design space modelling [Poster presentation]. Chimiométrie XIX - 2019, Montpellier, France. |
Deidda, R., Avohou, T. H., Baronti, R., Davolio, P. L., Pasquini, B., Del Bubba, M., Hubert, C., Hubert, P., Orlandini, S., & Furlanetto, S. (2019). Analytical quality by design: development and control strategy for a LC method to evaluate the cannabinoids content in cannabis olive oil extracts. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2019.01.032 Peer Reviewed verified by ORBi |
Huat, J., Dossou-Yovo, E., Guindo, M., Avohou, T. H., Furlan, T., Sanogo, F., & Touré, A. (2019). A spatial database of lowland cropping systems in Benin, Mali and Sierra Leone. Data in Brief, 24. doi:10.1016/j.dib.2019.103876 Peer Reviewed verified by ORBi |
Coic, L., Sacre, P.-Y., Avohou, T. H., Ciza, P., Marini Djang'Eing'A, R., Fillet, M., Hubert, P., & Ziemons, E. (01 January 2019). Authentication of falsified medicine tablets by handheld Raman spectroscopy class modeling [Paper presentation]. Chimiométrie 2019, Montpellier, France. |
Deidda, R., Avohou, T. H., Orlandini, S., Baronti, R., Pasquini, B., Furlanetto, S., Hubert, P., & Hubert, C. (19 December 2018). Control strategy applied to a LC-DAD quality control method as part of the analytical quality by design approach: one year of routine use [Paper presentation]. 1st CIRM Scientific Day, Liège, Belgium. |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (19 December 2018). SFC-MS for the quality control of cannabis: addressing the potential adulteration with synthetic cannabinoids [Paper presentation]. CIRM Day (1st edition). |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (19 October 2018). SFC-MS as a preventive tool for the quality control of potentially adulterated cannabis with synthetic cannabinoids [Paper presentation]. SFC 2018, Strasbourg, France. |
Avohou, T. H., Sacre, P.-Y., Lebrun, P., Hubert, P., & Ziemons, E. (12 September 2018). A novel probabilistic spectral matching strategy based on wavelets regression and Bayesian modeling for product identification and quality verification [Paper presentation]. 11th International Symposium on Drug Analysis and 29th International Symposium on Pharmaceutical and Biomedical Analysis, DA-PB, Leuven, Belgium. |
Deidda, R., Avohou, T. H., Orlandini, S., Baronti, R., Pasquini, B., Furlanetto, S., Hubert, P., & Hubert, C. (September 2018). Analytical Quality by Design: development and control strategy for a RP-HPLC method implemented in routine to evaluate the cannabinoids content in cannabis olive oil extracts [Poster presentation]. International Symposium DA-BPA 2018, Leuven, Belgium. |
Sacre, P.-Y., Coic, L., Avohou, T. H., Sakira, K., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (September 2018). Forensic formulation fingerprinting of falsified medicine by Raman hyperspectral imaging [Paper presentation]. Medicine Quality and Public Health 2018, Oxford, United Kingdom. |
Coic, L., Sacre, P.-Y., Avohou, T. H., Sakira, K., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (September 2018). Solving composition of falsified artemether/lumefantrine formulation by hyperspectral imaging [Poster presentation]. DA-PBA 2018 11th International Symposium on Drug Analysis (DA 2018), 29th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2018). |
Sacre, P.-Y., Avohou, T. H., Lebrun, P., Coic, L., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (September 2018). Bayesian securing of the pharmaceutical supply chain [Paper presentation]. Medicine Quality and Public Health 2018, Oxford, United Kingdom. |
Dispas, A., Avohou, T. H., Lebrun, P., Hubert, P., & Hubert, C. (April 2018). ‘Quality by Design’ approach for the analysis of impurities in pharmaceutical drug products and drug substances. TrAC: Trends in Analytical Chemistry, 101, 24-33. doi:10.1016/j.trac.2017.10.028 Peer Reviewed verified by ORBi |
Salvé, M., Avohou, T. H., Monbaliu, J.-C., Lebrun, P., Lemaire, C., Damblon, C., De Tullio, P., Hubert, P., Hustinx, R., & Luxen, A. (12 February 2018). NOTA‐PRGD2 and NODAGA‐PRGD2: Bioconjugation, characterization, radiolabelling, and design space. Journal of Labelled Compounds and Radiopharmaceuticals, 61, 487-500. doi:10.1002/jlcr.3613 Peer Reviewed verified by ORBi |
Avohou, T. H., Cailletaud, J., Clavaud, M., Coic, L., De Bleye, C., Deidda, R., Dumont, E., Sacre, P.-Y., Hubert, P., & Ziemons, E. (15 January 2018). De l'intérêt de la spectroscopie Raman pour l'analyse pharmaceutique [Paper presentation]. Conférence Universitaire de Suisse Occidentale, Genève, Switzerland. |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (2018). Quality control of medicinal cannabis: implementation of a generic sfc-ms method to address counterfeiting with synthetic cannabinoids [Poster presentation]. International Symposium DA-PBA 2018, Leuven, Belgium. |
Avohou, T. H., Hubert, C., Debrus, B., Lebrun, P., Rudaz, S., Boulanger, B., & Hubert, P. (2018). Statistical methods in Quality by Design approach to Liquid Chromatography method development. In S. Fekete & I. Molnar, Software-Assisted Method Development for Modeling High Performance Liquid Chromatography (pp. 109-150). London, United Kingdom: World Scientific Publishing. doi:10.1142/q0161 Peer reviewed |
Coic, L., Sacre, P.-Y., Avohou, T. H., Deidda, R., De Bleye, C., Dumont, E., Marini Djang'Eing'A, R., Hubert, P., & Ziemons, E. (2018). Recent developments of Raman spectroscopy for the qualitative analysis of falsified and substandard medicines. European Pharmaceutical Review. |
Jambo, H., Dispas, A., Avohou, T. H., André, S., Hubert, C., Lebrun, P., Ziemons, E., & Hubert, P. (2018). Implementation of a generic SFC-MS method for the quality control of potentially counterfeited medicinal cannabis with synthetic cannabinoids. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1092, 332-342. doi:10.1016/j.jchromb.2018.05.049 Peer Reviewed verified by ORBi |
Avohou, T. H., Cailletaud, J., Clavaud, M., De Bleye, C., Dumont, E., Marini Djang'Eing'A, R., Sacre, P.-Y., Hubert, P., & Ziemons, E. (20 September 2017). Modern spectral analyses fro drug identification and quantification: From PAT to patient protection [Paper presentation]. Arlenda Day, Bruxelles, Belgium. |
Avohou, T. H., Lambert, P., Govaerts, B., & Lebrun, P. (24 April 2017). Bayesian predictions of probabilities of out-of-specification drug products during a stability analysis [Poster presentation]. 6th International Biometric Society Channel Network Conference, Hasselt, Belgium. |
Mitchodigni, I. M., Amoussa Hounkpatin, W., Ntandou-Bouzitou, G., Avohou, T. H., Termote, C., Kennedy, G., & Hounhouigan1, J. D. (2017). Complementary feeding practices: determinants of dietary diversity and meal frequency among children aged 6–23 months in Southern Benin. Food Security, 9, 1117–1130. doi:10.1007/s12571-017-0722-y Peer Reviewed verified by ORBi |