Replacement of proline 174 with glutamic acid in GES-1 enzyme improve the flexibility of Ω-loop leading to an increase of catalytic efficiency towards carbapenems

Piccirilli, Alessandra; Perilli, Mariagrazia; Mercuri, Paola; Aschi, M.; Segatore, B; Galleni, Moreno; Celenza, G; Amicosante, Gianfranco

Poster (Scientific congresses and symposiums)

Piccirilli, Alessandra; Perilli, Mariagrazia; Mercuri, Paola et al.

2017 • 13th β-lactamase Meeting"

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https://hdl.handle.net/2268/217182

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Keywords :

GES-1 beta-lactamase

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Piccirilli, Alessandra

Perilli, Mariagrazia

Mercuri, Paola ; Université de Liège - ULiège > Département des sciences de la vie > Macromolécules biologiques

Aschi, M.

Segatore, B

Galleni, Moreno ; Université de Liège - ULiège > Département des sciences de la vie > Macromolécules biologiques

Celenza, G

Amicosante, Gianfranco

Language :

English

Title :

Replacement of proline 174 with glutamic acid in GES-1 enzyme improve the flexibility of Ω-loop leading to an increase of catalytic efficiency towards carbapenems

Publication date :

June 2017

Event name :

13th β-lactamase Meeting"

Event organizer :

University of L'Aquila, Prof. Perilli

Event place :

Santo Stefano di Sessanio, l'Aquila, Italy

Event date :

du 16 juin au 19 Juin 2017

Audience :

International

Available on ORBi :

since 18 December 2017

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