Poster (Scientific congresses and symposiums)
An anticancer molecule stemming from a plant root produced in a bioreactor
Vassaux, Antoine; Tarayre, Cédric; Delvigne, Frank et al.
2017Terra Innovation Game
 

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Keywords :
Astin C; Anticancer molecule; Heterologous expression; Support culture; Filamentous fungus; Villosirosea asteris
Abstract :
[en] Secondary metabolites produced by plants or their symbionts have already shown specific properties: anticancer, anti-inflammatory, antibacterial, antifungal effects, etc. Astin C is a non-ribosomal peptide (secondary metabolite) produced by the fungus Villosirosea asteris, endosymbiont of the medicinal plant Aster tataricus, which has shown an interesting anticancer activity. The current challenge is the production of the molecule on a large scale and in higher quantities, either from the original fungus through fermentation technologies, or by a heterologous yeast strain having integrated the genes involved in the astin C biosynthesis pathway. The purpose of this workshop is to highlight the implementation possibilities of a strain producing a metabolite of interest.
Disciplines :
Biotechnology
Author, co-author :
Vassaux, Antoine ;  Université de Liège - ULiège > Doct. sc. agro. & ingé. biol. (Paysage)
Tarayre, Cédric ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Microbial, food and biobased technologies
Delvigne, Frank  ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Microbial, food and biobased technologies
Fickers, Patrick ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Microbial, food and biobased technologies
Jacques, Philippe 
Vandenbol, Micheline ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Microbial, food and biobased technologies
Leclere, Valérie
Language :
English
Title :
An anticancer molecule stemming from a plant root produced in a bioreactor
Publication date :
24 May 2017
Number of pages :
A0
Event name :
Terra Innovation Game
Event date :
24 mai 2017
Audience :
International
Name of the research project :
Astinprod
Funders :
Programme ERA-IB
Available on ORBi :
since 29 May 2017

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