Chapter 11 - Validation of Supercritical Fluid Chromatography Methods

[en] Method validation is the process of proving that an analytical method is acceptable for its intended purpose. The present chapter defines the validation criteria described in regulatory documents. Despite the abundance of guidelines, the conclusion about method validity remains confused. In this context, the state-of-the-art validation methodology named total error approach is briefly explained as the methodology that should be followed for all method validations. Finally, a review of literature presents quantitative development and validation of supercritical fluid chromatography (SFC) methods considering a wide range of applications and analytical fields.

Research Center/Unit :

CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège

Disciplines :

Pharmacy, pharmacology & toxicology
Chemistry

Author, co-author :

Dispas, Amandine ; Université de Liège > Département de pharmacie > Chimie analytique

Lebrun, Pierre ; Université de Liège > Département de pharmacie > Chimie analytique

Hubert, Philippe ; Université de Liège > Département de pharmacie > Chimie analytique

Language :

English

Title :

Chapter 11 - Validation of Supercritical Fluid Chromatography Methods

Publication date :

2017

Main work title :

Supercritical Fluid Chromatography - Handbook in Separation Science

Editor :

Poole, Colin

Publisher :

Elsevier

Peer reviewed :

Peer reviewed

Available on ORBi :

since 20 March 2017

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