Assessing dynamical correlations between functional and structural brain connectivity

The link between resting­‐state functional connectivity (FC), measured by the correlations of the fMRI BOLD time courses, and structural connectivity (SC) has been repeatedly investigated recently. Meanwhile, the importance of considering the dynamics of neuronal processes has also been highlighted. In this work we show how the classical static (i.e. considered as constant) relationship between SC and FC could be enriched when the FC dynamics are taken into account.
We use a sliding window approach to explore these dynamics and show that the window width should be chosen in a particular range in order to unveil statistically significant (i.e. not due to noise) fluctuations of the FC-­‐SC correlation.