Genomic location of the bovine growth hormone secretagogue receptor (Ghsr) gene and investigation of genetic polymorphism

Colinet, Frédéric; Vanderick, Sylvie; Charloteaux, Benoît; Eggen, André; Gengler, Nicolas; Renaville, Bénédicte; Brasseur, Robert; Portetelle, Daniel; Renaville, Robert

doi:10.1080/10495390802602926

Article (Scientific journals)

Genomic location of the bovine growth hormone secretagogue receptor (Ghsr) gene and investigation of genetic polymorphism

Colinet, Frédéric; Vanderick, Sylvie; Charloteaux, Benoît et al.

2009 • In Animal Biotechnology, 20 (1), p. 28-33

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/16400

DOI
10.1080/10495390802602926

PubMed
19160085

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Keywords :

Cattle; GHSR; Polymorphism

Abstract :

[en] The growth hormone secretagogue receptor (GHSR) is involved in the regulation of energetic homeostasis and GH secretion. In this study, the bovine GHSR gene was mapped to BTA1 between BL26 and BMS4004. Two different bovine GHSR CDS (GHSR1a and GHSR1b) were sequenced. Six polymorphisms (five SNPs and one 3-bp indel) were also identified, three of them leading to amino acid variations L24V, D194N, and Del R242. These variations are located in the extracellular N-terminal end, the exoloop 2, and the cytoloop 3 of the receptor, respectively.

Disciplines :

Animal production & animal husbandry
Genetics & genetic processes

Author, co-author :

Colinet, Frédéric ; Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > Biologie animale et microbienne

Vanderick, Sylvie ; Université de Liège - ULiège > Sciences agronomiques > Zootechnie

Charloteaux, Benoît ; Université de Liège - ULiège > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie moléc. et numér.

Eggen, André; Institut Scientifique de Recherche Agronomique - INRA > UR339 Laboratoire de Génétique Biochimique et Cytogénétique

Gengler, Nicolas ; Université de Liège - ULiège > Sciences agronomiques > Zootechnie

Renaville, Bénédicte; University of Udine > Veterinary Physiology and Nutrition Unit

Brasseur, Robert ; Université de Liège - ULiège > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie moléc. et numér.

Portetelle, Daniel ; Université de Liège - ULiège > Chimie et bio-industries > Biologie animale et microbienne

Renaville, Robert ; Université de Liège - ULiège > Chimie et bio-industries > Biologie animale et microbienne

Language :

English

Title :

Genomic location of the bovine growth hormone secretagogue receptor (Ghsr) gene and investigation of genetic polymorphism

Publication date :

2009

Journal title :

Animal Biotechnology

ISSN :

1049-5398

eISSN :

1532-2378

Publisher :

Taylor & Francis Group, Philadelphia, United States - Pennsylvania

Volume :

Issue :

Pages :

28-33
28-33

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 09 July 2009

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