Profil

Colson Thomas

Département de pharmacie > Chimie pharmaceutique

CIRM

See author's contact details
ORCID
0000-0003-4828-1289
Main Referenced Co-authors
Francotte, Pierre  (12)
Pirotte, Bernard  (10)
Lesenfants, Cindy  (8)
Goffin, Eric  (7)
Bay, Y. (6)
Main Referenced Keywords
BPAM121 (6); BPAM344 (6); Alzheimer (5); AMPA (5); GluK1 (5);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (10)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (13)
Chemistry (4)

Publications (total 13)

The most downloaded
38 downloads
Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., De Tullio, P., Beaufour, C., Botez, I., Pickering, D., Frydenvang, K., Danober, L., Skov Kristensen, A., Sandholm Kastrup, J., & Pirotte, B. (09 December 2023). Exploring thienothiadiazine dioxides as isosteric analogues of benzo-and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry, 264, 116036. doi:10.1016/j.ejmech.2023.116036 https://hdl.handle.net/2268/312961

The most cited

9 citations (OpenCitations)

Etse, K. S., Dorosz, J., Mc Lain Christensen, Thomas, J.-Y., Botez Pop, I., Goffin, E., Colson, T., Lestage, P., Danober, L., Pirotte, B., Sandholm Katrup, J., & Francotte, P. (09 July 2021). Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3- hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors. ACS Chemical Neurosciences, 12 (14), 2679-2692. doi:10.1021/acschemneuro.1c00255 https://hdl.handle.net/2268/261395

Lesenfants, C., Goffin, E., Colson, T., Chaaya, N., Leroy, C., Garigliany, M.-M., Chavatte, P., Reboud-Ravaux, M., Pirotte, B., El Amri, C., & Francotte, P. (31 January 2024). RATIONAL DESIGN OF COUMARIN DERIVATIVES WITH A BASIC MOIETY FOR INHIBITING THE SERINE PROTEASE TMPRSS2: AN INNOVATIVE APPROACH TO COMBAT THE ENTRY OF SELECTED RESPIRATORY VIRUSES [Poster presentation]. CIRM Day, Liège, Belgium.
Editorial reviewed

Colson, T., Piette, M., Bay, Y., Pickering, D. S., Kristensen, A. S., Baudino, G., Tchekounang Tchonwa, I. F., Pochet, L., Goffin, E., Lesenfants, C., Kastrup, J. S., Pirotte, B., & Francotte, P. (31 January 2024). Advances in Targeting Kainic Acid Receptors: Developing Selective Positive Allosteric Modulators from the 1,2,4-Benzothiadiazine 1,1-Dioxide scaffold [Poster presentation]. CIRM Day 2024, Liège, Belgium.
Editorial reviewed

Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., De Tullio, P., Beaufour, C., Botez, I., Pickering, D., Frydenvang, K., Danober, L., Skov Kristensen, A., Sandholm Kastrup, J., & Pirotte, B. (09 December 2023). Exploring thienothiadiazine dioxides as isosteric analogues of benzo-and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry, 264, 116036. doi:10.1016/j.ejmech.2023.116036
Peer Reviewed verified by ORBi

Colson, T., Piette, M., Bay, Y., Pickering, D. S., Kristensen, A. S., Baudino, G., Tchekounang Tchonwa, I. F., Leroy, C., Pochet, L., Goffin, E., Lesenfants, C., & Kastrup, J. S. (08 December 2023). Kainic Acid Receptors: Innovating Selective Positive Allosteric Modulators based on 1,2,4-Benzothiadiazine 1,1-Dioxides [Poster presentation]. MedChem 2023, Bruxelles, Belgium.
Editorial reviewed

Lesenfants, C., Leroy, C., Goffin, E., Colson, T., Chaaya, N., Garigliany, M.-M., Chavatte, P., Reboud-Ravaux, M., Pirotte, B., El Amri, C., & Francotte, P. (08 December 2023). EXPLORING COUMARIN DERIVATIVES AS NOVEL ANTIVIRAL AGENTS TARGETING TMPRSS2: A MULTIDISCIPLINARY APPROACH FOR RESPIRATORY VIRAL DISEASE TREATMENT [Poster presentation]. MedChem 2023, Bruxelles, Belgium.
Editorial reviewed

Lesenfants, C., Leroy, C., Goffin, E., Colson, T., Garigliany, M.-M., Chavatte, P., Reboud, M., Pirotte, B., El Amri, C., & Francotte, P. (19 October 2023). Design of original serine protease inhibitors to combat viral respiratory infections: a synthetic pathway for new coumarinic compounds [Poster presentation]. 2023 SRC Scientific Day, Louvain-la-Neuve, Belgium.
Editorial reviewed

Colson, T., Piette, M., Bay, Y., Pickering, D. S., Kristensen, A. S., Goffin, E., Lesenfants, C., Kastrup, J. S., Pirotte, B., & Francotte, P. (19 October 2023). Glutamate Regulation: Synthesis of Selective Positive Allosteric Modulators of the Kainic Acid Receptors belonging to 1,2,4-Benzothiadiazine 1,1-Dioxides [Poster presentation]. SRC 2023 Scientific Day, Louvain-La-Neuve, Belgium.
Editorial reviewed

Colson, T., Valembois, S., Leroy, C., Bay, Y., Pickering, D. S., Kristensen, A. S., Pirotte, B., Kastrup, J. S., & Francotte, P. (07 September 2023). Design of potentiators targeting the allosteric pocket of the kainate subtype glutamate receptors [Poster presentation]. 10th EFMC Young Medicinal Chemist Symposium (EFMC-YMCS), Zagreb, Croatia.
Editorial reviewed

Leka, K., Colson, T., Lesenfants, C., Zhou, D., Garigliany, M.-M., Ledoux, A., & Francotte, P. (01 July 2023). HALOGENATION OF ETHANOL EXTRACT FROM PAEONIA SUFFRUTICOSA: EXPLORING PROMISING PATHWAYS FOR ANTI-SARS-COV-2 MEDICATION DEVELOPMENT [Poster presentation]. 6e Symposium International AFERP – 17 au 19 juillet 2023 –, Orsay, France.
Peer reviewed

Degotte, G., Frederich, M., Francotte, P., Franck, T., Colson, T., Serteyn, D., & Mouithys-Mickalad, A. (02 June 2023). Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and Analogues. Molecules, 28 (11), 4516. doi:10.3390/molecules28114516
Peer reviewed

Colson, T., Bay, Y., Pickering, D. S., Møllerud, S., Frydenvang, K., Pirotte, B., Mulle, C., Kristensen, A. S., Kastrup, J. S., & Francotte, P. (02 February 2022). Design and synthesis of key intermediates giving access to potentiators for the kainate subtype glutamate receptors [Poster presentation]. CIRM Day, Liège, Belgium.
Editorial reviewed

Colson, T., Valembois, S., Bay, Y., Pickering, D. S., Møllerud, S., Frydenvang, K., Pirotte, B., Mulle, C., Kristensen, A. S., Kastrup, J. S., & Francotte, P. (19 November 2021). Design of selective ligands for the kainate subtype receptors [Poster presentation]. MedChem 2021, Liège, Belgium.
Editorial reviewed

Etse, K. S., Dorosz, J., Mc Lain Christensen, Thomas, J.-Y., Botez Pop, I., Goffin, E., Colson, T., Lestage, P., Danober, L., Pirotte, B., Sandholm Katrup, J., & Francotte, P. (09 July 2021). Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3- hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors. ACS Chemical Neurosciences, 12 (14), 2679-2692. doi:10.1021/acschemneuro.1c00255
Peer Reviewed verified by ORBi

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