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Lesenfants Cindy

Département de pharmacie > Chimie pharmaceutique

CIRM

See author's contact details
ORCID
0009-0005-1673-5014
Main Referenced Co-authors
Colson, Thomas  (10)
Francotte, Pierre  (10)
Goffin, Eric  (10)
Pirotte, Bernard  (10)
El Amri, Chahrazade (5)
Main Referenced Keywords
AMPA (5); BPAM344 (5); 1,2,4-benzothiadiazine 1,1-dioxides (4); Allosteric (4); Alzheimer (4);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège (8)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (12)
Chemistry (5)

Publications (total 12)

The most downloaded
140 downloads
Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., De Tullio, P., Beaufour, C., Botez, I., Pickering, D., Frydenvang, K., Danober, L., Skov Kristensen, A., Sandholm Kastrup, J., & Pirotte, B. (09 December 2023). Exploring thienothiadiazine dioxides as isosteric analogues of benzo-and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry, 264, 116036. doi:10.1016/j.ejmech.2023.116036 https://hdl.handle.net/2268/312961

The most cited

2 citations (OpenAlex)

Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., De Tullio, P., Beaufour, C., Botez, I., Pickering, D., Frydenvang, K., Danober, L., Skov Kristensen, A., Sandholm Kastrup, J., & Pirotte, B. (09 December 2023). Exploring thienothiadiazine dioxides as isosteric analogues of benzo-and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry, 264, 116036. doi:10.1016/j.ejmech.2023.116036 https://hdl.handle.net/2268/312961

Lesenfants, C., Soualmia, F., Chaaya, N., Goffin, E., Colson, T., Garigliany, M.-M., Chavatte, P., Snoek, R., Andrei, G., Reboud-Ravaux, M., El Amri, C., Pirotte, B., & Francotte, P. (03 September 2024). RATIONAL DESIGN OF COUMARIN DERIVATIVES AS NEW INHIBITORS OF TRANSMEMBRANE SERINE PROTEASES TO TREAT RESPIRATORY VIRAL INFECTIONS [Poster presentation]. EFMC-ISMC, Rome, Italy.
Editorial reviewed

Colson, T., Baudino, G., Bay, Y., Pickering, D. S., Kristensen, A. S., Piette, M., Tchekounang Tchonwa, I. F., Pressia, J., Pochet, L., Goffin, E., Lesenfants, C., Kastrup, J. S., & Pirotte, B. (03 September 2024). Developing selective positive allosteric modulators for kainic acid receptors using the 1,2,4-benzothiadiazine 1,1-dioxide scaffold [Poster presentation]. EFMC-ISMC, Rome, Italy.
Editorial reviewed

Lesenfants, C., Goffin, E., Colson, T., Chaaya, N., Leroy, C., Garigliany, M.-M., Chavatte, P., Reboud-Ravaux, M., Pirotte, B., El Amri, C., & Francotte, P. (31 January 2024). RATIONAL DESIGN OF COUMARIN DERIVATIVES WITH A BASIC MOIETY FOR INHIBITING THE SERINE PROTEASE TMPRSS2: AN INNOVATIVE APPROACH TO COMBAT THE ENTRY OF SELECTED RESPIRATORY VIRUSES [Poster presentation]. CIRM Day, Liège, Belgium.
Editorial reviewed

Colson, T., Piette, M., Bay, Y., Pickering, D. S., Kristensen, A. S., Baudino, G., Tchekounang Tchonwa, I. F., Pochet, L., Goffin, E., Lesenfants, C., Kastrup, J. S., Pirotte, B., & Francotte, P. (31 January 2024). Advances in Targeting Kainic Acid Receptors: Developing Selective Positive Allosteric Modulators from the 1,2,4-Benzothiadiazine 1,1-Dioxide scaffold [Poster presentation]. CIRM Day 2024, Liège, Belgium.
Editorial reviewed

Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., De Tullio, P., Beaufour, C., Botez, I., Pickering, D., Frydenvang, K., Danober, L., Skov Kristensen, A., Sandholm Kastrup, J., & Pirotte, B. (09 December 2023). Exploring thienothiadiazine dioxides as isosteric analogues of benzo-and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry, 264, 116036. doi:10.1016/j.ejmech.2023.116036
Peer Reviewed verified by ORBi

Colson, T., Piette, M., Bay, Y., Pickering, D. S., Kristensen, A. S., Baudino, G., Tchekounang Tchonwa, I. F., Leroy, C., Pochet, L., Goffin, E., Lesenfants, C., & Kastrup, J. S. (08 December 2023). Kainic Acid Receptors: Innovating Selective Positive Allosteric Modulators based on 1,2,4-Benzothiadiazine 1,1-Dioxides [Poster presentation]. MedChem 2023, Bruxelles, Belgium.
Editorial reviewed

Lesenfants, C., Leroy, C., Goffin, E., Colson, T., Chaaya, N., Garigliany, M.-M., Chavatte, P., Reboud-Ravaux, M., Pirotte, B., El Amri, C., & Francotte, P. (08 December 2023). EXPLORING COUMARIN DERIVATIVES AS NOVEL ANTIVIRAL AGENTS TARGETING TMPRSS2: A MULTIDISCIPLINARY APPROACH FOR RESPIRATORY VIRAL DISEASE TREATMENT [Poster presentation]. MedChem 2023, Bruxelles, Belgium.
Editorial reviewed

Lesenfants, C., Leroy, C., Goffin, E., Colson, T., Garigliany, M.-M., Chavatte, P., Reboud, M., Pirotte, B., El Amri, C., & Francotte, P. (19 October 2023). Design of original serine protease inhibitors to combat viral respiratory infections: a synthetic pathway for new coumarinic compounds [Poster presentation]. 2023 SRC Scientific Day, Louvain-la-Neuve, Belgium.
Editorial reviewed

Colson, T., Piette, M., Bay, Y., Pickering, D. S., Kristensen, A. S., Goffin, E., Lesenfants, C., Kastrup, J. S., Pirotte, B., & Francotte, P. (19 October 2023). Glutamate Regulation: Synthesis of Selective Positive Allosteric Modulators of the Kainic Acid Receptors belonging to 1,2,4-Benzothiadiazine 1,1-Dioxides [Poster presentation]. SRC 2023 Scientific Day, Louvain-La-Neuve, Belgium.
Editorial reviewed

Leka, K., Colson, T., Lesenfants, C., Zhou, D., Garigliany, M.-M., Ledoux, A., & Francotte, P. (01 July 2023). HALOGENATION OF ETHANOL EXTRACT FROM PAEONIA SUFFRUTICOSA: EXPLORING PROMISING PATHWAYS FOR ANTI-SARS-COV-2 MEDICATION DEVELOPMENT [Poster presentation]. 6e Symposium International AFERP – 17 au 19 juillet 2023 –, Orsay, France.
Peer reviewed

Pirotte, B., Francotte, P., El Amri, C., Reboud-Ravaux, M., Chaaya, N., & Lesenfants, C. (2023). Substituted aryl esters of coumarin-3-carboxylic acid and their use as transmembrane serine protease 2 inhibitors and pharmaceutical composition.

Lesenfants, C., Goffin, E., Pirotte, B., Dammicco, S., & Francotte, P. (02 February 2022). Contribution to the synthesis of positive allosteric modulators of AMPA receptors for potential use in the early diagnosis of neurodegenerative diseases [Poster presentation]. CIRM Day, Liège, Belgium.
Editorial reviewed

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