  | Guiot, J., André, B., Potjewijd, J., JACQUERIE, P., Cremers, S., Henket, M., Idoufkir, L., Remacle, C., Tobal, R., GILTAY, L., Moermans, C., GESTER, F., Polese, B., Hamaïdia, M., Struman, I., Louis, E., Malaise, M., de Seny, D., van Paassen, P., ... Njock, M.-S. (2025). Association of fibrotic-related extracellular vesicle microRNAs with lung involvement in systemic sclerosis. European Respiratory Journal, 2400276. doi:10.1183/13993003.00276-2024  Peer Reviewed verified by ORBi |
  | Paulissen, G., Malaise, O., Deroyer, C., Charlier, E., Thirion, T., Daniel, C., Ribbens, C., & de Seny, D. (2024). Le tofacitinib et le baricitinib réduisent in vitro le catabolisme, l’inflammation et la fibrose dans les chondrocytes, les fibroblastes synoviaux et les explants de membrane synoviale de patients arthrosiques. Revue du Rhumatisme. Peer reviewed |
 | Paulissen, G.* , Malaise, O.* , Deroyer, C., Charlier, E., Thirion, T., Daniel, C., Ribbens, C., & de Seny, D. (19 September 2024). Tofacitinib and baricitinib alleviate metabolic dysregulation, inflammation and fibrosis in osteoarthritis: insights from human joint cells and synovium [Paper presentation]. Belgian Congress of Rheumatology 2024. Peer reviewed* These authors have contributed equally to this work. |
Nix, C., Sulejman, S., Cobraiville, G., Njock, M.-S., Paulissen, G., de Seny, D., & Fillet, M. (2024). Development of complementary analytical methods to characterize extracellular vesicles [Paper presentation]. CIRM Day, Liege, Belgium. |
Gendebien, Z., Deroyer, C., Poulet, C., Paulissen, G., Cobraiville, G., Daniel, C., Thirion, T., Bianchi, E., Delvenne, P., Ribbens, C., & de Seny, D. (2024). Secretion of endoplasmic reticulum chaperone proteins by subintimal synoviocytes is involved in synovitis [Poster presentation]. EULAR. |
 | JACQUERIE, P., André, B., de Seny, D., Henket, M., GILTAY, L., Ernst, M., Louis, R., Malaise, M., Ribbens, C., & Guiot, J. (03 November 2023). Reproducibility of pulmonary function tests in patients with systemic sclerosis. Scientific Reports, 13 (1), 18960. doi:10.1038/s41598-023-45881-y Peer Reviewed verified by ORBi |
 | Fusi, G., Constantinides, M., Fissoun, C., Pichard, L., Pers, Y.-M., Ferreira-Lopez, R., Pantesco, V., Poulet, C., Malaise, O., de Seny, D., Lemaitre, J.-M., Jorgensen, C., & Brondello, J.-M. (14 July 2023). Senescence-Driven Inflammatory and Trophic Microenvironment Imprints Mesenchymal Stromal/Stem Cells in Osteoarthritic Patients. Biomedicines, 11 (7), 1994. doi:10.3390/biomedicines11071994 Peer Reviewed verified by ORBi |
Nix, C., Ciregia Frederica, Cobraiville, G., de Seny, D., & Fillet, M. (24 May 2023). Microfluidic liquid chromatography coupled to drift-tube ion mobility and high-resolution mass spectrometry for the analysis of fibroblast-like synoviocytes stimulated with SAA variants [Paper presentation]. 39th International Symposium on Microscale Separation and Bioanalysis (MSB), Tallahassee, United States. Peer reviewed |
Nix, C., Ciregia, F., Cobraiville, G., de Seny, D., & Fillet, M. (01 February 2023). Micropillar array column coupled to drift-tube ion mobility and mass spectrometry for the analysis of fibroblast-like synoviocytes [Paper presentation]. CIRM Day, Liege, Belgium. |
Nix, C., Nys, G., Cobraiville, G., de Seny, D., & Fillet, M. (11 September 2022). Quantification of serum amyloid A variants in plasma, synovial fluid and cell culture medium to better understand rheumatoid arthritis [Poster presentation]. 12th International Symposium on Drug Analysis and the 32nd International Symposium on Pharmaceutical and Biomedical Analysis (DA-PBA 2022, Mons, Belgium. Peer reviewed |
 | DEROYER, C., Poulet, C., PAULISSEN, G., Ciregia, F., MALAISE, O., PLENER, Z., COBRAIVILLE, G., DANIEL, C., GILLET, P., MALAISE, M., & DE SENY, D. (2022). CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane. Cellular and Molecular Life Sciences. doi:10.1007/s00018-022-04282-6 Peer Reviewed verified by ORBi |
 | DE SENY, D., Baiwir, D., BIANCHI, E., COBRAIVILLE, G., DEROYER, C., Poulet, C., MALAISE, O., PAULISSEN, G., KAISER, M.-J., Hauzer, J.-P., Mazzucchelli, G., DELVENNE, P., & MALAISE, M. (2022). New Proteins Contributing to Immune Cell Infiltration and Pannus Formation of Synovial Membrane from Arthritis Diseases. International Journal of Molecular Sciences, 23 (1), 434. doi:10.3390/ijms23010434 Peer Reviewed verified by ORBi |
 | Papagiannopoulos, O. D., Papaloukas, C., Pezoulas, V. C., Van De Werken, H. J. G., Poulet, C., Mueller, Y. M., Katsikis, P. D., de Seny, D., & Fotiadis, D. I. (2022). Comparison of Proteomic Approaches in Autoinflammatory Disease Classification. In BHI-BSN 2022 - IEEE-EMBS International Conference on Biomedical and Health Informatics and IEEE-EMBS International Conference on Wearable and Implantable Body Sensor Networks, Symposium Proceedings. Institute of Electrical and Electronics Engineers Inc. doi:10.1109/BHI56158.2022.9926877 Editorial reviewed |
 | MALAISE, O., PAULISSEN, G., DEROYER, C., Cirgea, F., Poulet, C., LECHANTEUR, C., Brondello, J.-M., DE SENY, D., & MALAISE, M. (December 2021). Influence des glucocorticoïdes sur les caractéristiques de la sénescence cellulaire dans les fibroblastes synoviaux d’origine arthrosique. Revue du Rhumatisme, 88 (S1), 157. doi:10.1016/j.rhum.2021.10.248 Peer reviewed |
 | MALAISE, O.* , PAULISSEN, G.* , DEROYER, C., Ciregia, F., Poulet, C., NEUVILLE, S., PLENER, Z., DANIEL, C., Gillet, P., LECHANTEUR, C., Brondello, J.-M., DE SENY, D.* , & MALAISE, M.*. (16 November 2021). Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes. Journal of Clinical Medicine, 10 (22), 5331. doi:10.3390/jcm10225331 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | CIREGIA, F., Nys, G., Cobraiville, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Fillet, M., Malaise, M., & de Seny, D. (2021). A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis. Frontiers in Immunology. doi:10.3389/fimmu.2021.638814 Peer Reviewed verified by ORBi |
 | JACQUERIE, P., HENKET, M., André, B., MOERMANS, C., DE SENY, D., GESTER, F., LOUIS, R., MALAISE, M., & GUIOT, J. (21 May 2021). Inflammatory profile of induced sputum composition in systemic sclerosis and comparison with healthy volunteers. Scientific Reports, 11 (1), 10679. doi:10.1038/s41598-021-87701-1 Peer Reviewed verified by ORBi |
 | Ciregia, F., DEROYER, C., COBRAIVILLE, G., PLENER, Z., MALAISE, O., GILLET, P., Fillet, M., MALAISE, M., & DE SENY, D. (2021). Modulation of αVβ6 integrin in osteoarthritis-related synovitis and the interaction with VTN (381-397 a.a.) competing for TGF-β1 activation. Experimental and Molecular Medicine. doi:10.1038/s12276-021-00558-2 Peer Reviewed verified by ORBi |
 | GUIOT, J., NJOCK, M.-S., ANDRE, B., GESTER, F., HENKET, M., DE SENY, D., MOERMANS, C., MALAISE, M., & LOUIS, R. (2021). Serum IGFBP-2 in systemic sclerosis as a prognostic factor of lung dysfunction. Scientific Reports, 11 (1), 10882. doi:10.1038/s41598-021-90333-0 Peer Reviewed verified by ORBi |
DEROYER, C., CIREGIA, F., MALAISE, O., PAULISSEN, G., Poulet, C., Malaise, M., & DE SENY, D. (2021). Fibrosis in osteoarthritis – Role of Cemip [Paper presentation]. Fibrosis in immune-mediated inflammatory diseases : from pathophysiology to innovative treatment. |
 | RELIC, B., DEROYER, C., MALAISE, O., Plener, Z., Gillet, P., de Seny, D., & Malaise, M. (2021). TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells. Biochemical Journal, 478 (16), 3145-3155. doi:10.1042/BCJ20210174 Peer Reviewed verified by ORBi |
 | MALAISE, O., DE SENY, D., & RINKIN, C. (2020). Polyarthrite rhumatoïde : le CHU de Liège à la pointe de la recherche et de l'innovation. La Libre Belgique. |
 | CIREGIA, F., Nys, G., COBRAIVILLE, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Fillet, M., Malaise, M., & DE SENY, D. (December 2020). Caractérisation de l’expression des alarmines et des variants A-SAA dans la polyarthrite rhumatoïde débutante. Revue du Rhumatisme, 87 (S1), 126. doi:10.1016/j.rhum.2020.10.218 Peer reviewed |
 | DE SENY, D., BIANCHI, E., Baiwir, D., COBRAIVILLE, G., Collin, C., Deliège, M., KAISER, M.-J., Mazzucchelli, G., Hauzeur, J.-P., DELVENNE, P., & MALAISE, M. (May 2020). Proteins involved in the endoplasmic reticulum stress are key players in synovitis of osteoarthritis, chronic pyrophosphate arthropathy and rheumatoid arthritis, and correlate with the histological inflammatory score [Poster presentation]. OARSI, Vienna, Austria. |
 | de Seny, D., Bianchi, E., Baiwir, D., COBRAIVILLE, G., Collin, C., Deliège, M., Kaiser, M.-J., Mazzucchelli, G., Hauzeur, J.-P., Delvenne, P., & Malaise, M. (2020). Proteins involved in the endoplasmic reticulum stress are modulated in synovitis of osteoarthritis, chronic pyrophosphate arthropathy and rheumatoid arthritis, and correlate with the histological inflammatory score. Scientific Reports, 10 (1). doi:10.1038/s41598-020-70803-7 Peer Reviewed verified by ORBi |
 | Ciregia, F., Baiwir, D., COBRAIVILLE, G., DEWAEL, T., Mazzucchelli, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Malaise, M., & de Seny, D. (2020). Glycosylation deficiency of lipopolysaccharide-binding protein and corticosteroid-binding globulin associated with activity and response to treatment for rheumatoid arthritis. Journal of Translational Medicine, 18 (1). doi:10.1186/s12967-019-02188-9 Peer Reviewed verified by ORBi |
 | CHARLIER, E.* , DEROYER, C.* , NEUVILLE, S., Plener, Z., MALAISE, O., Ciregia, F., Gillet, P., Reuter, G., Salvé, M., Withofs, N., Hustinx, R., de Seny, D.* , & Malaise, M.*. (2020). Toward diagnostic relevance of the α(V)β(5), α(V)β(3), and α(V)β(6) integrins in OA: expression within human cartilage and spinal osteophytes. Bone Research, 8, 35. doi:10.1038/s41413-020-00110-4 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | CIREGIA, F., Baiwir, D., COBRAIVILLE, G., DEWAEL, T., Mazzucchelli, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Malaise, M., & DE SENY, D. (09 December 2019). Le déficit de la N-glycosylation de la corticosteroid–binding globulin et de la lipopolysaccharide–binding protein est associé à l'activité de la maladie et à la réponse au traitement dans la polyarthrite rhumatoïde [Paper presentation]. 32ème Congrès Français de Rhumatologie, Paris, France. |
 | DE SENY, D., BIANCHI, E., Baiwir, D., Mazzucchelli, G., DEROYER, C., CIREGIA, F., MALAISE, O., KAISER, M.-J., Hauzeur, J.-P., DELVENNE, P., & MALAISE, M. (09 December 2019). La protéomique synoviale identifie de nouvelles protéines corrélées au score inflammatoire histologique : comparaison entre arthrose, chondrocalcinose et polyarthrite rhumatöide [Paper presentation]. 32ème Congrès Français de Rhumatologie, Paris, France. |
 | Nys, G., COBRAIVILLE, G., Servais, A.-C., Malaise, M., DE SENY, D., & Fillet, M. (2019). Targeted proteomics reveals serum amyloid A variants and alarmins S100A8-S100A9 as key plasma biomarkers of rheumatoid arthritis. Talanta. doi:10.1016/j.talanta.2019.06.044 Peer reviewed |
 | Vaamonde-Garcia, C., MALAISE, O., CHARLIER, E., DEROYER, C., NEUVILLE, S., GILLET, P., Kurth, W., Meijide-Failde, R., MALAISE, M., & DE SENY, D. (2019). 15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts. Biochemical Pharmacology. doi:10.1016/j.bcp.2019.03.039 Peer Reviewed verified by ORBi |
 | MALAISE, O., & DE SENY, D. (2019). Therapeutic advances in arthritis diseases. Biochemical Pharmacology. doi:10.1016/j.bcp.2019.04.014 Peer Reviewed verified by ORBi |
 | Charlier, E., NEUVILLE, S., PLENER, Z., DEROYER, C., RELIC, B., MALAISE, O., REUTER, G., GILLET, P., Salvé, M., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (May 2019). EXPRESSION OF αVβ5, αVβ3 AND β6 INTEGRINS BY OSTEOARTHRITIC CHONDROCYTES AND VERTEBRAL OSTEOPHYTES [Poster presentation]. OARSI, Toronto, Canada. |
 | DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., MALAISE, M., & DE SENY, D. (May 2019). CEMIP (KIAA1199) induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2019, Toronto, Canada. |
 | DE SENY, D., DEROYER, C., Charlier, E., CIREGIA, F., COBRAIVILLE, G., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (May 2019). Increased serological levels of vitronectin(amino acid 381-397) and C3f peptides in osteoarthritis, lupus and scleroderma. Interaction with TGF-β [Poster presentation]. OARSI, Toronto, Canada. |
 | DEROYER, C., CHARLIER, E., NEUVILLE, S., MALAISE, O., GILLET, P., KURTH, W., Chariot, A., MALAISE, M., & DE SENY, D. (2019). CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes. Cell Death and Disease. doi:10.1038/s41419-019-1377-8 Peer Reviewed verified by ORBi |
 | Charlier, E., DEROYER, C., Ciregia, F., MALAISE, O., NEUVILLE, S., PLENER, Z., Malaise, M., & de Seny, D. (2019). Chondrocyte dedifferentiation and osteoarthritis (OA). Biochemical Pharmacology, 165, 49-65. doi:10.1016/j.bcp.2019.02.036 Peer Reviewed verified by ORBi |
 | BONHOMME, O., ANDRE, B., GESTER, F., DE SENY, D., MOERMANS, C., Struman, I., Louis, R., MALAISE, M., & GUIOT, J. (2019). Biomarkers in systemic sclerosis-associated interstitial lung disease: review of the literature. Rheumatology. doi:10.1093/rheumatology/kez230 Peer Reviewed verified by ORBi |
DEROYER, C., Charlier, E., Malaise, O., Malaise, M., & DE SENY, D. (10 December 2018). CEMIP accompagne l’expression de marqueurs de fibrose par le cartilage et la synoviale arthrosique [Poster presentation]. 31e congrès français de rhumatologie, Paris, France. |
 | DE SENY, D., COBRAIVILLE, G., DEROYER, C., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (10 December 2018). Elévation des taux sériques des peptides C3f et vitronectine (acide aminés 381-397) dans l’arthrose, le lupus et la sclérodermie. Interaction avec le TGF-β [Poster presentation]. 31ème Congrès Français de Rhumatologie, Paris, France. |
CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (April 2018). Regulation of α5 and β1 integrin expression by osteogenic or adipogenic differentiation as well as by TGFβ in human hip OA chondrocytes [Poster presentation]. 2018 World Congress on Osteoarthritis. |
 | Fosse, P., KAISER, M.-J., Namur, G., DE SENY, D., Malaise, M., & Hustinx, R. (2018). (18)F- FDG PET/CT joint assessment of early therapeutic response in rheumatoid arthritis patients treated with rituximab. European Journal of Hybrid Imaging, 2 (1), 6. doi:10.1186/s41824-017-0022-y Peer Reviewed verified by ORBi |
DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., Malaise, M., & DE SENY, D. (2018). CEMIP induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2018. |
 | RELIC, B., CHARLIER, A., DEROYER, C., MALAISE, O., Crine, Y., NEUVILLE, S., GILLET, P., DE SENY, D., & Malaise, M. (2018). Serum starvation raises turnover of phosphorylated p62/SQSTM1 (Serine 349), reveals expression of proteasome and N-glycanase1 interactive protein RAD23B and sensitizes human synovial fibroblasts to BAY 11-7085-induced cell death. Oncotarget, 9 (88), 35830-35843. doi:10.18632/oncotarget.26295 Peer Reviewed verified by ORBi |
 | CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (10 December 2017). Régulation de l’expression des intégrines a5 et ß1 par la différenciation ostéogénique ou adipogénique ainsi que par le TGFß dans les chondrocytes humains arthrosiques de hanche [Paper presentation]. 30ème Congrès Français de Rhumatologie. |
 | DE SENY, D., Baiwir, D., Collin, C., Deliège, M., DELVENNE, P., De Pauw, E., Hauzeur, J.-P., & MALAISE, M. (10 December 2017). Analyse protéomique de biopsies synoviales: comparaison entre arthrose, arthrose avec chondrocalcinose et polyarthrite rhumatoïde [Paper presentation]. 30ème Congrès Français de Rhumatologie, Paris, France. |
 | DEROYER, C., Charlier, E., Malaise, O., MALAISE, M., & DE SENY, D. (10 December 2017). Rôle de KIAA1199 dans le développement de l’arthrose [Paper presentation]. 30e congrès français de rhumatologie, Paris, France. |
 | Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique. |
Nys, G., COBRAIVILLE, G., DE SENY, D., & Fillet, M. (14 November 2017). Targeted analysis of potential biomarkers of rheumatoid arthritis by LC-MS/MS [Paper presentation]. CIRM seminar, Liège, Belgium. |
DEROYER, C., NEUVILLE, S., Charlier, E., MALAISE, O., MALAISE, M., & DE SENY, D. (28 April 2017). Role of KIAA1199 in osteoarthritic cartilage degradation [Poster presentation]. OARSI 2017. |
CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (April 2017). Regulation of αVβ3 and αVβ5 integrin complexes by osteogenic differentiation of human hip OA chondrocytes [Poster presentation]. 2017 World Congress on Osteoarthritis. |
 | Ourradi, K., Xu, Y., DE SENY, D., Kirwan, J., Blom, A., & Sharif, M. (2017). Development and validation of novel biomarker assays for osteoarthritis. PLoS ONE, 12 (7), 0181334. doi:10.1371/journal.pone.0181334 Peer Reviewed verified by ORBi |
 | COBRAIVILLE, G., Fillet, M., Sharif, M., Ourradi, K., Nys, G., Malaise, M., & DE SENY, D. (2017). Validation of a new method by nano-liquid chromatography on chip tandem mass spectrometry for combined quantitation of C3f and the V65 vitronectin fragment as biomarkers of diagnosis and severity of osteoarthritis. Talanta, 169, 170-180. doi:10.1016/j.talanta.2017.03.078 Peer Reviewed verified by ORBi |
 | CHARLIER, E., RELIC, B., Deroyer, C., MALAISE, O., NEUVILLE, S., Collée, J., MALAISE, M., & DE SENY, D. (2016). Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis. International Journal of Molecular Sciences. doi:10.3390/ijms17122146 Peer Reviewed verified by ORBi |
 | DE SENY, D., COBRAIVILLE, G., Leprince, P., Fillet, M., Collin, C., Mathieu, M., HAUZEUR, J.-P., Gangji, V., & Malaise, M. (2016). Biomarkers of inflammation and innate immunity in atrophic nonunion fracture. Journal of Translational Medicine. doi:10.1186/s12967-016-1019-1 Peer Reviewed verified by ORBi |
| RELIC, B., CHARLIER, E., Deroyer, C., MALAISE, O., NEUVILLE, S., Desoroux A, Gillet, P., DE SENY, D., & Malaise, M. (26 April 2016). BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget, 7 (17), 23370-82. doi:10.18632/oncotarget.8042 Peer Reviewed verified by ORBi |
Charlier, E., DEROYER, C., MALAISE, O., NEUVILLE, S., COBRAIVILLE, G., GILLET, P., KURTH, W., DE SENY, D., & MALAISE, M. (01 April 2016). Insights into the role of Dickkopf 3 (Dkk3) on Wnt/β-catenin and TGFβ ALK1/Smad1/5 signaling pathways as well as on leptin production during human hip OA chondrocytes dedifferentiation [Poster presentation]. OARSI 2016. |
 | CHARLIER, E., MALAISE, O., Deroyer, C., Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., Gillet, P., KURTH, W., De Seny, D., RELIC, B., & Malaise, M. (April 2016). Dickkopf 3 (Dkk3) is increased along human hip OA chondrocytes dedifferentiation and can modulate Wnt/Β-catenin and TGFβ Alk1/Smad1/5 signaling pathways, as well as leptin production [Poster presentation]. OARSI 2016 world congress. |
 | MALAISE, O., RELIC, B., Charlier, E., Zeddou, M., NEUVILLE, S., Deroyer, C., Gillet, P., Louis, E., Malaise, M., & DE SENY, D. (2016). Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts. Arthritis Research and Therapy, 18 (1), 219. doi:10.1186/s13075-016-1119-6 Peer Reviewed verified by ORBi |
 | CHARLIER, E.* , MALAISE, O.* , Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., DEROYER, C., Sanchez, C., Gillet, P., KURTH, W., DE SENY, D., RELIC, B., & MALAISE, M. (2016). Restriction of spontaneous and prednisolone-induced leptin production to dedifferentiated state in human hip OA chondrocytes: role of Smad1 and b-catenin activation. Osteoarthritis and Cartilage. doi:10.1016/j.joca.2015.08.002 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., LUTTERI, L., LE GOFF, C., MALAISE, D., MALAISE, O., CHAPELLE, J.-P., RELIC, B., & MALAISE, M. (2015). Apolipoprotein-A1 as a damage-associated molecular patterns protein in osteoarthritis: ex vivo and in vitro pro-inflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0122904 Peer Reviewed verified by ORBi |
 | WITHOFS, N., CHARLIER, E., Simoni, P., Alvarez-Miezentseva, V., Mievis, F., Giacomelli, F., Mella, C., Gambhir, S. S., Malaise, O., DE SENY, D., MALAISE, M., & HUSTINX, R. (2015). (18)F-FPRGD2 PET/CT imaging of musculoskeletal disorders. Annals of Nuclear Medicine, 29 (10), 839-47. doi:10.1007/s12149-015-1011-5 Peer Reviewed verified by ORBi |
 | MALAISE, O., RELIC, B., QUESADA CALVO, F., Charlier, E., Zeddou, M., NEUVILLE, S., Gillet, P., Louis, E., DE SENY, D., & MALAISE, M. (2015). Selective glucocorticoid receptor modulator compound A, in contrast to prednisolone, does not induce leptin or the leptin receptor in human osteoarthritis synovial fibroblasts. Rheumatology. doi:10.1093/rheumatology/keu428 Peer Reviewed verified by ORBi |
| MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & MALAISE, M. (08 December 2014). GILZ (Glucocorticoid-Induced Leuzine Zipper) est un intermédiaire de l’action des corticoïdes sur les cellules arthrosiques : implication dans la sécrétion de leptine et l’expression de son récepteur, mais pas dans les effets anti-inflammatoires [Paper presentation]. Congrès de la Société Française de Rhumatologie. |
| MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & Malaise, M. (24 September 2014). Leptin production by osteoarthritic synovial fibroblasts [Paper presentation]. Congrès de la Société Belge de Rhumatologie. |
| MALAISE, O., RELIC, B., NEUVILLE, S., Charlier, E., DE SENY, D., & MALAISE, M. (September 2014). Leptin production by osteoarthritis synovial fibroblasts: stimulation by glucocorticoids and mineralocorticoids through the glucocorticoid receptor and GILZ (Glucocorticoid-Induced Leucine Zipper) protein [Paper presentation]. Belgian Congress of Rheumatology, 2014. Peer reviewed |
 | De Bock, M., BEGUIN, Y., Leprince, P., WILLEMS, E., BARON, F., Deroyer, C., Seidel, L., CAVALIER, E., DE SENY, D., MALAISE, M., GOTHOT, A., MERVILLE, M.-P., & Fillet, M. (July 2014). Comprehensive plasma profiling for the characterization of graft-versus-host disease biomarkers. Talanta, 125, 265-275. doi:10.1016/j.talanta.2014.03.017 Peer Reviewed verified by ORBi |
| MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & MALAISE, M. (2014). Leptin Production By Osteoarthritis Synovial Fibroblasts: Stimulation By Glucocorticoids and Mineralocorticoids through the Glucocorticoid Receptor and GILZ (Glucocorticoid-Induced Leucine Zipper) Protein. Arthritis and Rheumatism, 66 (11), 454. Peer Reviewed verified by ORBi |
| MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & Malaise, M. (2014). The glucocorticoid-induced leucine zipper (GILZ) is involved in corticosteroid-induced leptin production by human osteoarthritis synovial fibroblasts in vitro. Osteoarthritis and Cartilage, 22, 449-450. Peer Reviewed verified by ORBi |
 | DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., Esser, N., MALAISE, D., MALAISE, O., Calvo, F., RELIC, B., & MALAISE, M. (2013). Acute-phase serum amyloid a in osteoarthritis: regulatory mechanism and proinflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0066769 Peer Reviewed verified by ORBi |
| MALAISE, O., RELIC, B., CHARLIER, E., zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2013). Compound A, un modulateur du récepteur aux glucocorticoïdes, ne stimule la production de leptine ni chez les fibroblastes synoviaux humains d’origine arthrosique, ni chez les chondrocytes dédifférenciés humains. Revue du Rhumatisme, 80 (1), 352. Peer Reviewed verified by ORBi |
| MALAISE, O., RELIC, B., CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & Malaise, M. (2013). Glucocorticoid receptor modulator Compound A does not induce leptin in human osteoarthritic synovial fibroblasts and in dedifferentiated chondrocytes. Arthritis and Rheumatism, 65 (10), 55. Peer Reviewed verified by ORBi |
| MALAISE, O., RELIC, B., CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2012). Human chondrocyte dedifferentiation is accompagnied by CD105 endoglin expression, ALK-1/Smad1/5 phosphorylation and leptin production – Stimulation by prednisolone and aldosterone through the glucocorticoid receptor. Arthritis and Rheumatism, 64 (10), 50. Peer Reviewed verified by ORBi |
| MALAISE, O.* , RELIC, B.* , CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2012). Les minéralocorticoïdes (aldostérone) stimulent la production de leptine des fibroblastes synoviaux d'origine arthrosique : implication du récepteur aux glucocorticoïdes, mais pas du récepteur aux minéralocorticoïdes. Revue du Rhumatisme, 79, 352. Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Zeddou, M., RELIC, B., MALAISE, O., CHARLIER, E., Desouroux, A., BEGUIN, Y., DE SENY, D., & Malaise, M. (2012). Differential signalling through ALK-1 and ALK-5 regulates leptin expression in Mesenchymal Stem Cells. Stem Cells and Development, 21 (11), 1948-54. doi:10.1089/scd.2011.0321 Peer Reviewed verified by ORBi |
 | DE SENY, D., Sharif, M., Fillet, M., COBRAIVILLE, G., Meuwis, M.-A., Marée, R., HAUZEUR, J.-P., Wehenkel, L., Louis, E., Merville, M.-P., Kirwan, J., Ribbens, C., & Malaise, M. (2011). Discovery and biochemical characterisation of four novel biomarkers for osteoarthritis. Annals of the Rheumatic Diseases, 70 (6), 1144-52. doi:10.1136/ard.2010.135541 Peer Reviewed verified by ORBi |
 | De Bock, M., De Seny, D., Meuwis, M.-A., Servais, A.-C., Minh, T. Q., Closset, J., Chapelle, J.-P., Louis, E., Malaise, M., Merville, M.-P., & Fillet, M. (2010). Comparison of three methods for fractionation and enrichment of low molecular weight proteins for SELDI-TOF-MS differential analysis. Talanta, 82, 245-254. doi:10.1016/j.talanta.2010.04.029 Peer Reviewed verified by ORBi |
 | De Seny, D., Ribbens, C., Cobraiville, G., Meuwis, M.-A., Marée, R., Geurts, P., Wehenkel, L., Louis, E., Merville, M.-P., Fillet, M., & Malaise, M. (2009). Protéomique par SELDI-TOF-MS des maladies inflammatoires articulaires: identification des protéines S100 comme protéines d'intérêt. Revue Médicale de Liège, 64 (Spec No), 29-35. Peer reviewed |
 | Relic, B., Zeddou, M., Desoroux, A., Beguin, Y., De Seny, D., & Malaise, M. (2009). Genistein induces adipogenesis but inhibits leptin induction in human synovial fibroblasts. Laboratory Investigation, 89 (7), 811-822. doi:10.1038/labinvest.2009.41 Peer Reviewed verified by ORBi |
 | De Bock, M., De Seny, D., Meuwis, M.-A., Chapelle, J.-P., Louis, E., Malaise, M., Merville, M.-P., & Fillet, M. (2009). Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS. Journal of Biomedicine and Biotechnology. doi:10.1155/2010/906082 Peer Reviewed verified by ORBi |
 | Quesada Calvo, F.* , Fillet, M.* , De Seny, D., Meuwis, M.-A., Marée, R., Crahay, C., Paulissen, G., Rocks, N., Guéders, M., Wehenkel, L., Merville, M.-P., Louis, R., Foidart, J.-M., Noël, A., & Cataldo, D. (2009). Biomarker discovery in asthma-related inflammation and remodeling. Proteomics, 9 (8), 2163-2170. doi:10.1002/pmic.200800643 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Meuwis, M.-A.* , Fillet, M.* , Lutteri, L., Marée, R., Geurts, P., De Seny, D., Malaise, M., Chapelle, J.-P., Wehenkel, L., Belaiche, J., Merville, M.-P.* , & Louis, E.*. (2008). Proteomics for prediction and characterization of response to infliximab in Crohn's disease: a pilot study. Clinical Biochemistry, 41 (12), 960-7. doi:10.1016/j.clinbiochem.2008.04.021 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | De Seny, D., Fillet, M., Ribbens, C., Marée, R., Meuwis, M.-A., Lutteri, L., Chapelle, J.-P., Wehenkel, L., Louis, E., Merville, M.-P., & Malaise, M. (2008). Monomeric calgranulins measured by SELDI-TOF mass spectrometry and calprotectin measured by ELISA as biomarkers in arthritis. Clinical Chemistry, 54, 1066-1075. doi:10.1373/clinchem.2007.099549 Peer Reviewed verified by ORBi |
 | Meuwis, M.-A.* , Fillet, M.* , Geurts, P., De Seny, D., Lutteri, L., Chapelle, J.-P., Bours, V., Wehenkel, L., Belaiche, J., Malaise, M., Louis, E., & Merville, M.-P. (2007). Biomarker discovery for inflammatory bowel disease, using proteomic serum profiling. Biochemical Pharmacology, 73 (9), 1422-1433. doi:10.1016/j.bcp.2006.12.019 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | De Seny, D.* , Fillet, M.* , Meuwis, M.-A., Geurts, P., Lutteri, L., Ribbens, C., Bours, V., Wehenkel, L., Piette, J., Malaise, M., & Merville, M.-P. (2005). Discovery of new rheumatoid arthritis biomarkers using the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry ProteinChip approach. Arthritis and Rheumatism, 52 (12), 3801-12. doi:10.1002/art.21607 Peer Reviewed verified by ORBi* These authors have contributed equally to this work. |
 | Geurts, P., Fillet, M., De Seny, D., Meuwis, M.-A., Malaise, M., Merville, M.-P., & Wehenkel, L. (2005). Proteomic mass spectra classification using decision tree based ensemble methods. Bioinformatics, 21 (14), 3138-45. doi:10.1093/bioinformatics/bti494 Peer Reviewed verified by ORBi |
De Seny, D., Fillet, M., Meuwis, M.-A., Lutteri, L., Geurts, P., Wehenkel, L., Bours, V., Piette, J., Malaise, M., & Merville, M.-P. (September 2004). Discovery of new rheumatoid arthritis biomarkers using SELDI-TOF-MS ProteinChip approach. Arthritis and Rheumatism, 50 (9, Suppl. S), 124. |
 | Prosperi, C., De Seny, D., Llabres, G., Galleni, M., & Lamotte-Brasseur, J. (December 2002). Active-site mutants of class B beta-lactamases: substrate binding and mechanistic study. Cellular and Molecular Life Sciences, 59 (12), 2136-2143. doi:10.1007/s000180200013 Peer Reviewed verified by ORBi |
 | De Seny, D., Prosperi, C., Bebrone, C., Rossolini, G. M., Page, M. I., Noel, P., Frère, J.-M., & Galleni, M. (01 May 2002). Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase. Biochemical Journal, 363 (Pt 3), 687-696. doi:10.1042/bj3630687 Peer Reviewed verified by ORBi |
 | De Seny, D., Heinz, U., Wommer, S., Kiefer, M., Meyer-Klaucke, W., Galleni, M., Frère, J.-M., Bauer, R., & Adolph, H. W. (30 November 2001). Metal Ion Binding and Coordination Geometry for Wild Type and Mutants of Metallo-Beta -Lactamase from Bacillus Cereus 569/H/9 (Bcii): A Combined Thermodynamic, Kinetic, and Spectroscopic Approach. Journal of Biological Chemistry, 276 (48), 45065-78. doi:10.1074/jbc.M106447200 Peer Reviewed verified by ORBi |
 | Prosperi, C., Llabres, G., De Seny, D., Soto, R. P., Valladares, M. H., Laraki, N., Frère, J.-M., & Galleni, M. (25 January 1999). Interaction between Class B Beta-Lactamases and Suicide Substrates of Active-Site Serine Beta-Lactamases. FEBS Letters, 443 (2), 109-11. doi:10.1016/S0014-5793(98)01689-5 Peer Reviewed verified by ORBi |
 | Paul-Soto, R., Bauer, R., Frère, J.-M., Galleni, M., Meyer-Klaucke, W., Nolting, H., Rossolini, G. M., DE SENY, D., Hernandez-Valladares, M., Zeppezauer, M., & Adolph, H. W. (1999). Mono- and binuclear Zn2+-beta-lactamase. Role of the conserved cysteine in the catalytic mechanism. Journal of Biological Chemistry, 274 (19), 13242-9. doi:10.1074/jbc.274.19.13242 Peer Reviewed verified by ORBi |
Dataset: