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NEUVILLE Sophie

Département de médecine interne > Service de rhumatologie

See author's contact details
Main Referenced Co-authors
De Seny, Dominique  (31)
Malaise, Michel  (31)
Malaise, Olivier  (31)
Charlier, Edith  (29)
Relic, Biserka  (22)
Main Referenced Keywords
Osteoarthritis (4); Fibrosis (3); osteoarthritis (3); Chondrocytes (2); Glucocorticoids (2);
Main Referenced Unit & Research Centers
Laboratory of Rheumatology, GIGA Research, University of Liège, CHU Liège, Liège, Belgium (1)
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE] (1)
Main Referenced Disciplines
Rheumatology (29)
Biochemistry, biophysics & molecular biology (6)
Gastroenterology & hepatology (1)
Radiology, nuclear medicine & imaging (1)

Publications (total 31)

The most downloaded
211 downloads
DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., Esser, N., MALAISE, D., MALAISE, O., Calvo, F., RELIC, B., & MALAISE, M. (2013). Acute-phase serum amyloid a in osteoarthritis: regulatory mechanism and proinflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0066769 https://hdl.handle.net/2268/163374

The most cited

265 citations (Scopus®)

Charlier, E., DEROYER, C., Ciregia, F., MALAISE, O., NEUVILLE, S., PLENER, Z., Malaise, M., & de Seny, D. (2019). Chondrocyte dedifferentiation and osteoarthritis (OA). Biochemical Pharmacology, 165, 49-65. doi:10.1016/j.bcp.2019.02.036 https://hdl.handle.net/2268/263525

MALAISE, O.* , PAULISSEN, G.* , DEROYER, C., Ciregia, F., Poulet, C., NEUVILLE, S., PLENER, Z., DANIEL, C., Gillet, P., LECHANTEUR, C., Brondello, J.-M., DE SENY, D.* , & MALAISE, M.*. (16 November 2021). Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes. Journal of Clinical Medicine, 10 (22), 5331. doi:10.3390/jcm10225331
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

CHARLIER, E.* , DEROYER, C.* , NEUVILLE, S., Plener, Z., MALAISE, O., Ciregia, F., Gillet, P., Reuter, G., Salvé, M., Withofs, N., Hustinx, R., de Seny, D., & Malaise, M. (2020). Toward diagnostic relevance of the α(V)β(5), α(V)β(3), and α(V)β(6) integrins in OA: expression within human cartilage and spinal osteophytes. Bone Research, 8, 35. doi:10.1038/s41413-020-00110-4
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Vaamonde-Garcia, C., MALAISE, O., CHARLIER, E., DEROYER, C., NEUVILLE, S., GILLET, P., Kurth, W., Meijide-Failde, R., MALAISE, M., & DE SENY, D. (2019). 15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts. Biochemical Pharmacology. doi:10.1016/j.bcp.2019.03.039
Peer Reviewed verified by ORBi

Charlier, E., NEUVILLE, S., PLENER, Z., DEROYER, C., RELIC, B., MALAISE, O., REUTER, G., GILLET, P., Salvé, M., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (May 2019). EXPRESSION OF αVβ5, αVβ3 AND β6 INTEGRINS BY OSTEOARTHRITIC CHONDROCYTES AND VERTEBRAL OSTEOPHYTES [Poster presentation]. OARSI, Toronto, Canada.

DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., MALAISE, M., & DE SENY, D. (May 2019). CEMIP (KIAA1199) induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2019, Toronto, Canada.

DEROYER, C., CHARLIER, E., NEUVILLE, S., MALAISE, O., GILLET, P., KURTH, W., Chariot, A., MALAISE, M., & DE SENY, D. (2019). CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes. Cell Death and Disease. doi:10.1038/s41419-019-1377-8
Peer Reviewed verified by ORBi

Charlier, E., DEROYER, C., Ciregia, F., MALAISE, O., NEUVILLE, S., PLENER, Z., Malaise, M., & de Seny, D. (2019). Chondrocyte dedifferentiation and osteoarthritis (OA). Biochemical Pharmacology, 165, 49-65. doi:10.1016/j.bcp.2019.02.036
Peer Reviewed verified by ORBi

CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (April 2018). Regulation of α5 and β1 integrin expression by osteogenic or adipogenic differentiation as well as by TGFβ in human hip OA chondrocytes [Poster presentation]. 2018 World Congress on Osteoarthritis.

RELIC, B., CHARLIER, A., DEROYER, C., MALAISE, O., Crine, Y., NEUVILLE, S., GILLET, P., DE SENY, D., & Malaise, M. (2018). Serum starvation raises turnover of phosphorylated p62/SQSTM1 (Serine 349), reveals expression of proteasome and N-glycanase1 interactive protein RAD23B and sensitizes human synovial fibroblasts to BAY 11-7085-induced cell death. Oncotarget, 9 (88), 35830-35843. doi:10.18632/oncotarget.26295
Peer Reviewed verified by ORBi

DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., Malaise, M., & DE SENY, D. (2018). CEMIP induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2018.

CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (10 December 2017). Régulation de l’expression des intégrines a5 et ß1 par la différenciation ostéogénique ou adipogénique ainsi que par le TGFß dans les chondrocytes humains arthrosiques de hanche [Paper presentation]. 30ème Congrès Français de Rhumatologie.

DEROYER, C., NEUVILLE, S., Charlier, E., MALAISE, O., MALAISE, M., & DE SENY, D. (28 April 2017). Role of KIAA1199 in osteoarthritic cartilage degradation [Poster presentation]. OARSI 2017.

CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (April 2017). Regulation of αVβ3 and αVβ5 integrin complexes by osteogenic differentiation of human hip OA chondrocytes [Poster presentation]. 2017 World Congress on Osteoarthritis.

CHARLIER, E., RELIC, B., Deroyer, C., MALAISE, O., NEUVILLE, S., Collée, J., MALAISE, M., & DE SENY, D. (2016). Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis. International Journal of Molecular Sciences. doi:10.3390/ijms17122146
Peer Reviewed verified by ORBi

RELIC, B., CHARLIER, E., Deroyer, C., MALAISE, O., NEUVILLE, S., Desoroux A, Gillet, P., DE SENY, D., & Malaise, M. (26 April 2016). BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget, 7 (17), 23370-82. doi:10.18632/oncotarget.8042
Peer Reviewed verified by ORBi

Charlier, E., DEROYER, C., MALAISE, O., NEUVILLE, S., COBRAIVILLE, G., GILLET, P., KURTH, W., DE SENY, D., & MALAISE, M. (01 April 2016). Insights into the role of Dickkopf 3 (Dkk3) on Wnt/β-catenin and TGFβ ALK1/Smad1/5 signaling pathways as well as on leptin production during human hip OA chondrocytes dedifferentiation [Poster presentation]. OARSI 2016.

CHARLIER, E., MALAISE, O., Deroyer, C., Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., Gillet, P., KURTH, W., De Seny, D., RELIC, B., & Malaise, M. (April 2016). Dickkopf 3 (Dkk3) is increased along human hip OA chondrocytes dedifferentiation and can modulate Wnt/Β-catenin and TGFβ Alk1/Smad1/5 signaling pathways, as well as leptin production [Poster presentation]. OARSI 2016 world congress.

MALAISE, O., RELIC, B., Charlier, E., Zeddou, M., NEUVILLE, S., Deroyer, C., Gillet, P., Louis, E., Malaise, M., & DE SENY, D. (2016). Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts. Arthritis Research and Therapy, 18 (1), 219. doi:10.1186/s13075-016-1119-6
Peer Reviewed verified by ORBi

CHARLIER, E.* , MALAISE, O.* , Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., DEROYER, C., Sanchez, C., Gillet, P., KURTH, W., DE SENY, D., RELIC, B., & MALAISE, M. (2016). Restriction of spontaneous and prednisolone-induced leptin production to dedifferentiated state in human hip OA chondrocytes: role of Smad1 and b-catenin activation. Osteoarthritis and Cartilage. doi:10.1016/j.joca.2015.08.002
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., LUTTERI, L., LE GOFF, C., MALAISE, D., MALAISE, O., CHAPELLE, J.-P., RELIC, B., & MALAISE, M. (2015). Apolipoprotein-A1 as a damage-associated molecular patterns protein in osteoarthritis: ex vivo and in vitro pro-inflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0122904
Peer Reviewed verified by ORBi

MALAISE, O., RELIC, B., QUESADA CALVO, F., Charlier, E., Zeddou, M., NEUVILLE, S., Gillet, P., Louis, E., DE SENY, D., & MALAISE, M. (2015). Selective glucocorticoid receptor modulator compound A, in contrast to prednisolone, does not induce leptin or the leptin receptor in human osteoarthritis synovial fibroblasts. Rheumatology. doi:10.1093/rheumatology/keu428
Peer Reviewed verified by ORBi

MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & MALAISE, M. (08 December 2014). GILZ (Glucocorticoid-Induced Leuzine Zipper) est un intermédiaire de l’action des corticoïdes sur les cellules arthrosiques : implication dans la sécrétion de leptine et l’expression de son récepteur, mais pas dans les effets anti-inflammatoires [Paper presentation]. Congrès de la Société Française de Rhumatologie.

MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & Malaise, M. (24 September 2014). Leptin production by osteoarthritic synovial fibroblasts [Paper presentation]. Congrès de la Société Belge de Rhumatologie.

MALAISE, O., RELIC, B., NEUVILLE, S., Charlier, E., DE SENY, D., & MALAISE, M. (September 2014). Leptin production by osteoarthritis synovial fibroblasts: stimulation by glucocorticoids and mineralocorticoids through the glucocorticoid receptor and GILZ (Glucocorticoid-Induced Leucine Zipper) protein [Paper presentation]. Belgian Congress of Rheumatology, 2014.
Peer reviewed

MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & MALAISE, M. (2014). Leptin Production By Osteoarthritis Synovial Fibroblasts: Stimulation By Glucocorticoids and Mineralocorticoids through the Glucocorticoid Receptor and GILZ (Glucocorticoid-Induced Leucine Zipper) Protein. Arthritis and Rheumatism, 66 (11), 454.
Peer Reviewed verified by ORBi

MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & Malaise, M. (2014). The glucocorticoid-induced leucine zipper (GILZ) is involved in corticosteroid-induced leptin production by human osteoarthritis synovial fibroblasts in vitro. Osteoarthritis and Cartilage, 22, 449-450.
Peer Reviewed verified by ORBi

DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., Esser, N., MALAISE, D., MALAISE, O., Calvo, F., RELIC, B., & MALAISE, M. (2013). Acute-phase serum amyloid a in osteoarthritis: regulatory mechanism and proinflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0066769
Peer Reviewed verified by ORBi

MALAISE, O., RELIC, B., CHARLIER, E., zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2013). Compound A, un modulateur du récepteur aux glucocorticoïdes, ne stimule la production de leptine ni chez les fibroblastes synoviaux humains d’origine arthrosique, ni chez les chondrocytes dédifférenciés humains. Revue du Rhumatisme, 80 (1), 352.
Peer Reviewed verified by ORBi

MALAISE, O., RELIC, B., CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & Malaise, M. (2013). Glucocorticoid receptor modulator Compound A does not induce leptin in human osteoarthritic synovial fibroblasts and in dedifferentiated chondrocytes. Arthritis and Rheumatism, 65 (10), 55.
Peer Reviewed verified by ORBi

MALAISE, O., RELIC, B., CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2012). Human chondrocyte dedifferentiation is accompagnied by CD105 endoglin expression, ALK-1/Smad1/5 phosphorylation and leptin production – Stimulation by prednisolone and aldosterone through the glucocorticoid receptor. Arthritis and Rheumatism, 64 (10), 50.
Peer Reviewed verified by ORBi

MALAISE, O.* , RELIC, B.* , CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2012). Les minéralocorticoïdes (aldostérone) stimulent la production de leptine des fibroblastes synoviaux d'origine arthrosique : implication du récepteur aux glucocorticoïdes, mais pas du récepteur aux minéralocorticoïdes. Revue du Rhumatisme, 79, 352.
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

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