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Deroyer Céline

GIGA I3 - Rheumatology

See author's contact details
ORCID
0000-0002-5399-0891
Main Referenced Co-authors
De Seny, Dominique  (31)
Malaise, Michel  (31)
Malaise, Olivier  (28)
Charlier, Edith  (20)
Neuville, Sophie  (19)
Main Referenced Keywords
autophagy (4); Osteoarthritis (4); Fibrosis (3); ceramide (2); Chondrocytes (2);
Main Referenced Unit & Research Centers
Centre Interfacultaire de Recherche du Médicament - CIRM (1)
Giga-Signal Transduction - ULiège [BE] (1)
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE] (1)
Main Referenced Disciplines
Rheumatology (28)
Biochemistry, biophysics & molecular biology (14)
Cardiovascular & respiratory systems (4)
Laboratory medicine & medical technology (3)
General & internal medicine (2)

Publications (total 41)

The most downloaded
143 downloads
Le Goff, C., Garweg, C., Laurent, T., Kaux, J.-F., Deroyer, C., Merville, M.-P., Melon, P., Fillet, M., Legrand, V., & Chapelle, J.-P. (July 2010). Assessment of high sensitive troponin T and I immunoassays in patients with acute chest. Clinical Chemistry, 56 (S6), 127. https://hdl.handle.net/2268/63133

The most cited

265 citations (Scopus®)

Charlier, E., DEROYER, C., Ciregia, F., MALAISE, O., NEUVILLE, S., PLENER, Z., Malaise, M., & de Seny, D. (2019). Chondrocyte dedifferentiation and osteoarthritis (OA). Biochemical Pharmacology, 165, 49-65. doi:10.1016/j.bcp.2019.02.036 https://hdl.handle.net/2268/263525

DE SENY, D., Baiwir, D., BIANCHI, E., COBRAIVILLE, G., DEROYER, C., Poulet, C., MALAISE, O., PAULISSEN, G., KAISER, M.-J., Hauzer, J.-P., Mazzucchelli, G., DELVENNE, P., & MALAISE, M. (2022). New Proteins Contributing to Immune Cell Infiltration and Pannus Formation of Synovial Membrane from Arthritis Diseases. International Journal of Molecular Sciences, 23 (1), 434. doi:10.3390/ijms23010434
Peer Reviewed verified by ORBi

DEROYER, C., Poulet, C., PAULISSEN, G., Ciregia, F., MALAISE, O., PLENER, Z., COBRAIVILLE, G., DANIEL, C., GILLET, P., MALAISE, M., & DE SENY, D. (2022). CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane. Cellular and Molecular Life Sciences. doi:10.1007/s00018-022-04282-6
Peer Reviewed verified by ORBi

MALAISE, O., PAULISSEN, G., DEROYER, C., Cirgea, F., Poulet, C., LECHANTEUR, C., Brondello, J.-M., DE SENY, D., & MALAISE, M. (December 2021). Influence des glucocorticoïdes sur les caractéristiques de la sénescence cellulaire dans les fibroblastes synoviaux d’origine arthrosique. Revue du Rhumatisme, 88 (S1), 157.
Peer reviewed

MALAISE, O.* , PAULISSEN, G.* , DEROYER, C., Ciregia, F., Poulet, C., NEUVILLE, S., PLENER, Z., DANIEL, C., Gillet, P., LECHANTEUR, C., Brondello, J.-M., DE SENY, D.* , & MALAISE, M.*. (16 November 2021). Influence of Glucocorticoids on Cellular Senescence Hallmarks in Osteoarthritic Fibroblast-like Synoviocytes. Journal of Clinical Medicine, 10 (22), 5331. doi:10.3390/jcm10225331
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Ciregia, F., DEROYER, C., COBRAIVILLE, G., PLENER, Z., MALAISE, O., GILLET, P., Fillet, M., MALAISE, M., & DE SENY, D. (2021). Modulation of αVβ6 integrin in osteoarthritis-related synovitis and the interaction with VTN (381-397 a.a.) competing for TGF-β1 activation. Experimental and Molecular Medicine. doi:10.1038/s12276-021-00558-2
Peer Reviewed verified by ORBi

DEROYER, C., CIREGIA, F., MALAISE, O., PAULISSEN, G., Poulet, C., Malaise, M., & DE SENY, D. (2021). Fibrosis in osteoarthritis – Role of Cemip [Paper presentation]. Fibrosis in immune-mediated inflammatory diseases : from pathophysiology to innovative treatment.

RELIC, B., DEROYER, C., MALAISE, O., Plener, Z., Gillet, P., de Seny, D., & Malaise, M. (2021). TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells. Biochemical Journal, 478 (16), 3145-3155. doi:10.1042/BCJ20210174
Peer Reviewed verified by ORBi

CHARLIER, E.* , DEROYER, C.* , NEUVILLE, S., Plener, Z., MALAISE, O., Ciregia, F., Gillet, P., Reuter, G., Salvé, M., Withofs, N., Hustinx, R., de Seny, D., & Malaise, M. (2020). Toward diagnostic relevance of the α(V)β(5), α(V)β(3), and α(V)β(6) integrins in OA: expression within human cartilage and spinal osteophytes. Bone Research, 8, 35. doi:10.1038/s41413-020-00110-4
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

DE SENY, D., BIANCHI, E., Baiwir, D., Mazzucchelli, G., DEROYER, C., CIREGIA, F., MALAISE, O., KAISER, M.-J., Hauzeur, J.-P., DELVENNE, P., & MALAISE, M. (09 December 2019). La protéomique synoviale identifie de nouvelles protéines corrélées au score inflammatoire histologique : comparaison entre arthrose, chondrocalcinose et polyarthrite rhumatöide [Paper presentation]. 32ème Congrès Français de Rhumatologie, Paris, France.

Vaamonde-Garcia, C., MALAISE, O., CHARLIER, E., DEROYER, C., NEUVILLE, S., GILLET, P., Kurth, W., Meijide-Failde, R., MALAISE, M., & DE SENY, D. (2019). 15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts. Biochemical Pharmacology. doi:10.1016/j.bcp.2019.03.039
Peer Reviewed verified by ORBi

Charlier, E., NEUVILLE, S., PLENER, Z., DEROYER, C., RELIC, B., MALAISE, O., REUTER, G., GILLET, P., Salvé, M., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (May 2019). EXPRESSION OF αVβ5, αVβ3 AND β6 INTEGRINS BY OSTEOARTHRITIC CHONDROCYTES AND VERTEBRAL OSTEOPHYTES [Poster presentation]. OARSI, Toronto, Canada.

DE SENY, D., DEROYER, C., Charlier, E., CIREGIA, F., COBRAIVILLE, G., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (May 2019). Increased serological levels of vitronectin(amino acid 381-397) and C3f peptides in osteoarthritis, lupus and scleroderma. Interaction with TGF-β [Poster presentation]. OARSI, Toronto, Canada.

DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., MALAISE, M., & DE SENY, D. (May 2019). CEMIP (KIAA1199) induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2019, Toronto, Canada.

DEROYER, C., CHARLIER, E., NEUVILLE, S., MALAISE, O., GILLET, P., KURTH, W., Chariot, A., MALAISE, M., & DE SENY, D. (2019). CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes. Cell Death and Disease. doi:10.1038/s41419-019-1377-8
Peer Reviewed verified by ORBi

Charlier, E., DEROYER, C., Ciregia, F., MALAISE, O., NEUVILLE, S., PLENER, Z., Malaise, M., & de Seny, D. (2019). Chondrocyte dedifferentiation and osteoarthritis (OA). Biochemical Pharmacology, 165, 49-65. doi:10.1016/j.bcp.2019.02.036
Peer Reviewed verified by ORBi

DEROYER, C., Charlier, E., Malaise, O., Malaise, M., & DE SENY, D. (10 December 2018). CEMIP accompagne l’expression de marqueurs de fibrose par le cartilage et la synoviale arthrosique [Poster presentation]. 31e congrès français de rhumatologie, Paris, France.

DE SENY, D., COBRAIVILLE, G., DEROYER, C., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (10 December 2018). Elévation des taux sériques des peptides C3f et vitronectine (acide aminés 381-397) dans l’arthrose, le lupus et la sclérodermie. Interaction avec le TGF-β [Poster presentation]. 31ème Congrès Français de Rhumatologie, Paris, France.

CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (April 2018). Regulation of α5 and β1 integrin expression by osteogenic or adipogenic differentiation as well as by TGFβ in human hip OA chondrocytes [Poster presentation]. 2018 World Congress on Osteoarthritis.

RELIC, B., CHARLIER, A., DEROYER, C., MALAISE, O., Crine, Y., NEUVILLE, S., GILLET, P., DE SENY, D., & Malaise, M. (2018). Serum starvation raises turnover of phosphorylated p62/SQSTM1 (Serine 349), reveals expression of proteasome and N-glycanase1 interactive protein RAD23B and sensitizes human synovial fibroblasts to BAY 11-7085-induced cell death. Oncotarget, 9 (88), 35830-35843. doi:10.18632/oncotarget.26295
Peer Reviewed verified by ORBi

DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., Malaise, M., & DE SENY, D. (2018). CEMIP induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2018.

CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (10 December 2017). Régulation de l’expression des intégrines a5 et ß1 par la différenciation ostéogénique ou adipogénique ainsi que par le TGFß dans les chondrocytes humains arthrosiques de hanche [Paper presentation]. 30ème Congrès Français de Rhumatologie.

DEROYER, C., Charlier, E., Malaise, O., MALAISE, M., & DE SENY, D. (10 December 2017). Rôle de KIAA1199 dans le développement de l’arthrose [Paper presentation]. 30e congrès français de rhumatologie, Paris, France.

DEROYER, C., NEUVILLE, S., Charlier, E., MALAISE, O., MALAISE, M., & DE SENY, D. (28 April 2017). Role of KIAA1199 in osteoarthritic cartilage degradation [Poster presentation]. OARSI 2017.

CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (April 2017). Regulation of αVβ3 and αVβ5 integrin complexes by osteogenic differentiation of human hip OA chondrocytes [Poster presentation]. 2017 World Congress on Osteoarthritis.

CHARLIER, E., RELIC, B., Deroyer, C., MALAISE, O., NEUVILLE, S., Collée, J., MALAISE, M., & DE SENY, D. (2016). Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis. International Journal of Molecular Sciences. doi:10.3390/ijms17122146
Peer Reviewed verified by ORBi

RELIC, B., CHARLIER, E., Deroyer, C., MALAISE, O., NEUVILLE, S., Desoroux A, Gillet, P., DE SENY, D., & Malaise, M. (26 April 2016). BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget, 7 (17), 23370-82. doi:10.18632/oncotarget.8042
Peer Reviewed verified by ORBi

Charlier, E., DEROYER, C., MALAISE, O., NEUVILLE, S., COBRAIVILLE, G., GILLET, P., KURTH, W., DE SENY, D., & MALAISE, M. (01 April 2016). Insights into the role of Dickkopf 3 (Dkk3) on Wnt/β-catenin and TGFβ ALK1/Smad1/5 signaling pathways as well as on leptin production during human hip OA chondrocytes dedifferentiation [Poster presentation]. OARSI 2016.

CHARLIER, E., MALAISE, O., Deroyer, C., Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., Gillet, P., KURTH, W., De Seny, D., RELIC, B., & Malaise, M. (April 2016). Dickkopf 3 (Dkk3) is increased along human hip OA chondrocytes dedifferentiation and can modulate Wnt/Β-catenin and TGFβ Alk1/Smad1/5 signaling pathways, as well as leptin production [Poster presentation]. OARSI 2016 world congress.

MALAISE, O., RELIC, B., Charlier, E., Zeddou, M., NEUVILLE, S., Deroyer, C., Gillet, P., Louis, E., Malaise, M., & DE SENY, D. (2016). Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts. Arthritis Research and Therapy, 18 (1), 219. doi:10.1186/s13075-016-1119-6
Peer Reviewed verified by ORBi

CHARLIER, E.* , MALAISE, O.* , Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., DEROYER, C., Sanchez, C., Gillet, P., KURTH, W., DE SENY, D., RELIC, B., & MALAISE, M. (2016). Restriction of spontaneous and prednisolone-induced leptin production to dedifferentiated state in human hip OA chondrocytes: role of Smad1 and b-catenin activation. Osteoarthritis and Cartilage. doi:10.1016/j.joca.2015.08.002
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Deroyer, C., Magne, J., Moonen, M., Le Goff, C., Dupont, L., Hulin, A., Radermecker, M., Colige, A., Cavalier, E., Kolh, P., Pierard, L., LANCELLOTTI, P., Merville, M.-P., & Fillet, M. (2015). New biomarkers for primary mitral regurgitation. Clinical Proteomics, 12, 25. doi:10.1186/s12014-015-9097-2
Peer Reviewed verified by ORBi

De Bock, M., BEGUIN, Y., Leprince, P., WILLEMS, E., BARON, F., Deroyer, C., Seidel, L., CAVALIER, E., DE SENY, D., MALAISE, M., GOTHOT, A., MERVILLE, M.-P., & Fillet, M. (July 2014). Comprehensive plasma profiling for the characterization of graft-versus-host disease biomarkers. Talanta, 125, 265-275. doi:10.1016/j.talanta.2014.03.017
Peer Reviewed verified by ORBi

DEROYER, C. (2014). Proteomic study of primary mitral regurgitation. Implication of autophagy in cellular signalling [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/182279

Deroyer, C., Renert, A.-F., Merville, M.-P., & Fillet, M. (2014). New role for Emerin, a key inner nuclear membrane protein, as an enhancer of the autophagosome formation in the C16-ceramide autophagy pathway. Autophagy. doi:10.4161/auto.28777
Peer Reviewed verified by ORBi

Fillet, M., Deroyer, C., COBRAIVILLE, G., LE GOFF, C., Cavalier, E., Chapelle, J.-P., Marée, R., Legrand, V., Pierard, L., Kolh, P., & Merville, M.-P. (2013). Identification of protein biomarkers associated with cardiac ischemia by a proteomic approach. Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 18 (7), 614-24. doi:10.3109/1354750X.2013.838306
Peer Reviewed verified by ORBi

DEROYER, C., Renert, A.-F., Merville, M.-P., & Fillet, M. (25 May 2012). Identification of new emerin partners in ceramide signalling pathway [Paper presentation]. Belgian Society of Biochemistry and Molecular Biology: Proteomics and interactomics in signaling networks.

Merville, M.-P., Deroyer, C., Bruyère, O., & Reginster, J.-Y. (March 2011). Strontium ranelate increases cell viability in IL-1 beta stimulated human chondrocytes [Paper presentation]. 1st IOF-ESCEO Pre-clinical Symposium (2011), European Congress on Osteoporosis and Osteoarthritis ECCEO11-IOF, Valencia, Spain.

Merville, M.-P., Deroyer, C., Bruyère, O., & Reginster, J.-Y. (November 2010). Le ranélate de strontium augmente la viabilité de chondrocytes humains stimulés par IL-1 bêta. Revue du Rhumatisme, 77 (Suppl.3), 222.
Peer Reviewed verified by ORBi

Le Goff, C., Garweg, C., Laurent, T., Kaux, J.-F., Deroyer, C., Merville, M.-P., Melon, P., Fillet, M., Legrand, V., & Chapelle, J.-P. (July 2010). Assessment of high sensitive troponin T and I immunoassays in patients with acute chest. Clinical Chemistry, 56 (S6), 127.
Peer Reviewed verified by ORBi

Le Goff, C., Laurent, T., Garweg, C., Kaux, J.-F., Deroyer, C., Fillet, M., Lancellotti, P., Pierard, L., & Chapelle, J.-P. (July 2010). Does echocardiographic stress test induced release of hsTnT and TnI II? Clinical Chemistry, 56 (S6), 128.
Peer Reviewed verified by ORBi

DEROYER, C. (2007). Etude protéomique de l'insuffisance cardiaque. Recherche et identification de biomarqueurs des maladies coronariennes [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/182277

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