CHARLIER, E.* , DEROYER, C.* , NEUVILLE, S., Plener, Z., MALAISE, O., Ciregia, F., Gillet, P., Reuter, G., Salvé, M., Withofs, N., Hustinx, R., de Seny, D., & Malaise, M. (2020). Toward diagnostic relevance of the α(V)β(5), α(V)β(3), and α(V)β(6) integrins in OA: expression within human cartilage and spinal osteophytes. Bone Research, 8, 35. doi:10.1038/s41413-020-00110-4 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Vaamonde-Garcia, C., MALAISE, O., CHARLIER, E., DEROYER, C., NEUVILLE, S., GILLET, P., Kurth, W., Meijide-Failde, R., MALAISE, M., & DE SENY, D. (2019). 15-Deoxy-Δ-12, 14-prostaglandin J2 acts cooperatively with prednisolone to reduce TGF-β-induced pro-fibrotic pathways in human osteoarthritis fibroblasts. Biochemical Pharmacology. doi:10.1016/j.bcp.2019.03.039 Peer Reviewed verified by ORBi |
Charlier, E., NEUVILLE, S., PLENER, Z., DEROYER, C., RELIC, B., MALAISE, O., REUTER, G., GILLET, P., Salvé, M., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (May 2019). EXPRESSION OF αVβ5, αVβ3 AND β6 INTEGRINS BY OSTEOARTHRITIC CHONDROCYTES AND VERTEBRAL OSTEOPHYTES [Poster presentation]. OARSI, Toronto, Canada. |
DE SENY, D., DEROYER, C., Charlier, E., CIREGIA, F., COBRAIVILLE, G., MEUWIS, M.-A., LOUIS, E., Fillet, M., & MALAISE, M. (May 2019). Increased serological levels of vitronectin(amino acid 381-397) and C3f peptides in osteoarthritis, lupus and scleroderma. Interaction with TGF-β [Poster presentation]. OARSI, Toronto, Canada. |
DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., MALAISE, M., & DE SENY, D. (May 2019). CEMIP (KIAA1199) induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2019, Toronto, Canada. |
DEROYER, C., CHARLIER, E., NEUVILLE, S., MALAISE, O., GILLET, P., KURTH, W., Chariot, A., MALAISE, M., & DE SENY, D. (2019). CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes. Cell Death and Disease. doi:10.1038/s41419-019-1377-8 Peer Reviewed verified by ORBi |
Charlier, E., DEROYER, C., Ciregia, F., MALAISE, O., NEUVILLE, S., PLENER, Z., Malaise, M., & de Seny, D. (2019). Chondrocyte dedifferentiation and osteoarthritis (OA). Biochemical Pharmacology, 165, 49-65. doi:10.1016/j.bcp.2019.02.036 Peer Reviewed verified by ORBi |
DEROYER, C., Charlier, E., Malaise, O., Malaise, M., & DE SENY, D. (10 December 2018). CEMIP accompagne l’expression de marqueurs de fibrose par le cartilage et la synoviale arthrosique [Poster presentation]. 31e congrès français de rhumatologie, Paris, France. |
CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (April 2018). Regulation of α5 and β1 integrin expression by osteogenic or adipogenic differentiation as well as by TGFβ in human hip OA chondrocytes [Poster presentation]. 2018 World Congress on Osteoarthritis. |
DEROYER, C., Charlier, E., NEUVILLE, S., MALAISE, O., Malaise, M., & DE SENY, D. (2018). CEMIP induces a fibrosis-like process in OA chondrocytes [Poster presentation]. OARSI 2018. |
CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., DE SENY, D., & MALAISE, M. (10 December 2017). Régulation de l’expression des intégrines a5 et ß1 par la différenciation ostéogénique ou adipogénique ainsi que par le TGFß dans les chondrocytes humains arthrosiques de hanche [Paper presentation]. 30ème Congrès Français de Rhumatologie. |
DEROYER, C., Charlier, E., Malaise, O., MALAISE, M., & DE SENY, D. (10 December 2017). Rôle de KIAA1199 dans le développement de l’arthrose [Paper presentation]. 30e congrès français de rhumatologie, Paris, France. |
DEROYER, C., NEUVILLE, S., Charlier, E., MALAISE, O., MALAISE, M., & DE SENY, D. (28 April 2017). Role of KIAA1199 in osteoarthritic cartilage degradation [Poster presentation]. OARSI 2017. |
CHARLIER, E., NEUVILLE, S., RELIC, B., DEROYER, C., MALAISE, O., KURTH, W., GILLET, P., WITHOFS, N., HUSTINX, R., DE SENY, D., & MALAISE, M. (April 2017). Regulation of αVβ3 and αVβ5 integrin complexes by osteogenic differentiation of human hip OA chondrocytes [Poster presentation]. 2017 World Congress on Osteoarthritis. |
CHARLIER, E., RELIC, B., Deroyer, C., MALAISE, O., NEUVILLE, S., Collée, J., MALAISE, M., & DE SENY, D. (2016). Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis. International Journal of Molecular Sciences. doi:10.3390/ijms17122146 Peer Reviewed verified by ORBi |
RELIC, B., CHARLIER, E., Deroyer, C., MALAISE, O., NEUVILLE, S., Desoroux A, Gillet, P., DE SENY, D., & Malaise, M. (26 April 2016). BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget, 7 (17), 23370-82. doi:10.18632/oncotarget.8042 Peer Reviewed verified by ORBi |
Charlier, E., DEROYER, C., MALAISE, O., NEUVILLE, S., COBRAIVILLE, G., GILLET, P., KURTH, W., DE SENY, D., & MALAISE, M. (01 April 2016). Insights into the role of Dickkopf 3 (Dkk3) on Wnt/β-catenin and TGFβ ALK1/Smad1/5 signaling pathways as well as on leptin production during human hip OA chondrocytes dedifferentiation [Poster presentation]. OARSI 2016. |
CHARLIER, E., MALAISE, O., Deroyer, C., Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., Gillet, P., KURTH, W., De Seny, D., RELIC, B., & Malaise, M. (April 2016). Dickkopf 3 (Dkk3) is increased along human hip OA chondrocytes dedifferentiation and can modulate Wnt/Β-catenin and TGFβ Alk1/Smad1/5 signaling pathways, as well as leptin production [Poster presentation]. OARSI 2016 world congress. |
MALAISE, O., RELIC, B., Charlier, E., Zeddou, M., NEUVILLE, S., Deroyer, C., Gillet, P., Louis, E., Malaise, M., & DE SENY, D. (2016). Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts. Arthritis Research and Therapy, 18 (1), 219. doi:10.1186/s13075-016-1119-6 Peer Reviewed verified by ORBi |
CHARLIER, E.* , MALAISE, O.* , Zeddou, M., NEUVILLE, S., COBRAIVILLE, G., DEROYER, C., Sanchez, C., Gillet, P., KURTH, W., DE SENY, D., RELIC, B., & MALAISE, M. (2016). Restriction of spontaneous and prednisolone-induced leptin production to dedifferentiated state in human hip OA chondrocytes: role of Smad1 and b-catenin activation. Osteoarthritis and Cartilage. doi:10.1016/j.joca.2015.08.002 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., LUTTERI, L., LE GOFF, C., MALAISE, D., MALAISE, O., CHAPELLE, J.-P., RELIC, B., & MALAISE, M. (2015). Apolipoprotein-A1 as a damage-associated molecular patterns protein in osteoarthritis: ex vivo and in vitro pro-inflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0122904 Peer Reviewed verified by ORBi |
WITHOFS, N., CHARLIER, E., Simoni, P., Alvarez-Miezentseva, V., Mievis, F., Giacomelli, F., Mella, C., Gambhir, S. S., Malaise, O., DE SENY, D., MALAISE, M., & HUSTINX, R. (2015). (18)F-FPRGD2 PET/CT imaging of musculoskeletal disorders. Annals of Nuclear Medicine, 29 (10), 839-47. doi:10.1007/s12149-015-1011-5 Peer Reviewed verified by ORBi |
MALAISE, O., RELIC, B., QUESADA CALVO, F., Charlier, E., Zeddou, M., NEUVILLE, S., Gillet, P., Louis, E., DE SENY, D., & MALAISE, M. (2015). Selective glucocorticoid receptor modulator compound A, in contrast to prednisolone, does not induce leptin or the leptin receptor in human osteoarthritis synovial fibroblasts. Rheumatology. doi:10.1093/rheumatology/keu428 Peer Reviewed verified by ORBi |
MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & MALAISE, M. (08 December 2014). GILZ (Glucocorticoid-Induced Leuzine Zipper) est un intermédiaire de l’action des corticoïdes sur les cellules arthrosiques : implication dans la sécrétion de leptine et l’expression de son récepteur, mais pas dans les effets anti-inflammatoires [Paper presentation]. Congrès de la Société Française de Rhumatologie. |
MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & Malaise, M. (24 September 2014). Leptin production by osteoarthritic synovial fibroblasts [Paper presentation]. Congrès de la Société Belge de Rhumatologie. |
MALAISE, O., RELIC, B., NEUVILLE, S., Charlier, E., DE SENY, D., & MALAISE, M. (September 2014). Leptin production by osteoarthritis synovial fibroblasts: stimulation by glucocorticoids and mineralocorticoids through the glucocorticoid receptor and GILZ (Glucocorticoid-Induced Leucine Zipper) protein [Paper presentation]. Belgian Congress of Rheumatology, 2014. Peer reviewed |
MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & MALAISE, M. (2014). Leptin Production By Osteoarthritis Synovial Fibroblasts: Stimulation By Glucocorticoids and Mineralocorticoids through the Glucocorticoid Receptor and GILZ (Glucocorticoid-Induced Leucine Zipper) Protein. Arthritis and Rheumatism, 66 (11), 454. Peer Reviewed verified by ORBi |
MALAISE, O., RELIC, B., NEUVILLE, S., CHARLIER, E., DE SENY, D., & Malaise, M. (2014). The glucocorticoid-induced leucine zipper (GILZ) is involved in corticosteroid-induced leptin production by human osteoarthritis synovial fibroblasts in vitro. Osteoarthritis and Cartilage, 22, 449-450. Peer Reviewed verified by ORBi |
DE SENY, D., COBRAIVILLE, G., CHARLIER, E., NEUVILLE, S., Esser, N., MALAISE, D., MALAISE, O., Calvo, F., RELIC, B., & MALAISE, M. (2013). Acute-phase serum amyloid a in osteoarthritis: regulatory mechanism and proinflammatory properties. PLoS ONE. doi:10.1371/journal.pone.0066769 Peer Reviewed verified by ORBi |
MALAISE, O., RELIC, B., CHARLIER, E., zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2013). Compound A, un modulateur du récepteur aux glucocorticoïdes, ne stimule la production de leptine ni chez les fibroblastes synoviaux humains d’origine arthrosique, ni chez les chondrocytes dédifférenciés humains. Revue du Rhumatisme, 80 (1), 352. Peer Reviewed verified by ORBi |
MALAISE, O., RELIC, B., CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & Malaise, M. (2013). Glucocorticoid receptor modulator Compound A does not induce leptin in human osteoarthritic synovial fibroblasts and in dedifferentiated chondrocytes. Arthritis and Rheumatism, 65 (10), 55. Peer Reviewed verified by ORBi |
MALAISE, O., RELIC, B., CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2012). Human chondrocyte dedifferentiation is accompagnied by CD105 endoglin expression, ALK-1/Smad1/5 phosphorylation and leptin production – Stimulation by prednisolone and aldosterone through the glucocorticoid receptor. Arthritis and Rheumatism, 64 (10), 50. Peer Reviewed verified by ORBi |
MALAISE, O.* , RELIC, B.* , CHARLIER, E., Zeddou, M., QUESADA-CALVO, F., NEUVILLE, S., DE SENY, D., & MALAISE, M. (2012). Les minéralocorticoïdes (aldostérone) stimulent la production de leptine des fibroblastes synoviaux d'origine arthrosique : implication du récepteur aux glucocorticoïdes, mais pas du récepteur aux minéralocorticoïdes. Revue du Rhumatisme, 79, 352. Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Zeddou, M., RELIC, B., MALAISE, O., CHARLIER, E., Desouroux, A., BEGUIN, Y., DE SENY, D., & Malaise, M. (2012). Differential signalling through ALK-1 and ALK-5 regulates leptin expression in Mesenchymal Stem Cells. Stem Cells and Development, 21 (11), 1948-54. doi:10.1089/scd.2011.0321 Peer Reviewed verified by ORBi |
CHARLIER, E. (2010). Role of SHIP-1 in the regulation of CD95/APO-1/Fas-induced apoptosis in T lymphocytes [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/263550 |
Charlier, E., Condé, C., Zhang, J., Deneubourg, L., Di Valentin, E., Rahmouni, S., Chariot, A., Agostinis, P., Pang, P.-C., Haslam, S., Dell, A., Penninger, J., Erneux, C., Piette, J., & Gloire, G. (2010). SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity. Leukemia. doi:10.1038/leu.2010.9 Peer Reviewed verified by ORBi |
Gloire, G., Charlier, E., & Piette, J. (2008). Regulation of CD95/APO-1/Fas-induced apoptosis by protein phosphatases. Biochemical Pharmacology. doi:10.1016/j.bcp.2008.06.023 Peer Reviewed verified by ORBi |
Gloire, G., Charlier, E., Rahmouni, S., Volanti, C., Chariot, A., Erneux, C., & Piette, J. (2006). Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress. Oncogene, 25 (40), 5485-94. doi:10.1038/sj.onc.1209542 Peer Reviewed verified by ORBi |