Scale-down assessment of the sensitivity of Yarrowia lipolytica to oxygen transfer and foam management in bioreactors: investigation of the underlying physiological mechanisms
Destain, Jacqueline ; Université de Liège - ULiège > Chimie et bio-industries > Bio-industries
Thonart, Philippe ; Université de Liège - ULiège > Département des sciences de la vie > Biochimie et microbiologie industrielles
Delvigne, Frank ; Université de Liège - ULiège > Chimie et bio-industries > Bio-industries
Language :
English
Title :
Scale-down assessment of the sensitivity of Yarrowia lipolytica to oxygen transfer and foam management in bioreactors: investigation of the underlying physiological mechanisms
Publication date :
2012
Journal title :
Journal of Industrial Microbiology and Biotechnology
A Beopoulos J Cescut R Haddouche JL Uribelarrea C Molina-Jouve JM Nicaud 2009 Yarrowia lipolytica as a model for bio-oil production Prog Lipid Res 48 375 387 19720081 10.1016/j.plipres.2009.08.005 1:CAS:528:DC%2BD1MXht1WmsrvJ
A Beopoulos T Chardot JM Nicaud 2009 Yarrowia lipolytica: a model and tool to understand the mechanisms implicated in lipid accumulation Biochimie 91 692 696 19248816 10.1016/j.biochi.2009.02.004 1:CAS:528:DC%2BD1MXmtVCjt7g%3D
F Delvigne J Destain P Thonart 2006 A methodology for the design of scale-down bioreactors by the use of mixing and circulation stochastic models Biochem Eng J 28 3 256 268 10.1016/j.bej.2005.11.009 1:CAS:528: DC%2BD28XitVKns7o%3D
Delvigne F, Lecomte JP (2010) Foam formation and control in bioreactors. In: Encyclopedia on industrial biotechnology: bioprocess, bioseparation and cell technologies. Wiley, (in press)
J Destain P Fickers F Weeckers B Moreau P Thonart 2005 Utilization of methyloelate in production of microbial lipase Appl Biochem Biotechnol 121-124 269 278 15917605 10.1385/ABAB:121:1-3:0269
SO Enfors M Jahic A Rozkov B Xu M Hecker B Jürgen E Krüger T Schweder G Hamer D O'Beirne N Noisommit-Rizzi M Reuss L Boone C Hewitt C McFarlane A Nienow T Kovacs C Trägardh L Fuchs J Revstedt PC Friberg B Hjertager G Blomsten H Skogman S Hjort F Hoeks HY Lin P Neubauer R van der Lans K Luyben P Vrabel A Manelius 2001 Physiological responses to mixing in large scale bioreactors J Biotechnol 85 175 185 11165362 10.1016/S0168-1656(00)00365-5 1:CAS:528:DC%2BD3MXpsVGrsw%3D%3D
A Etoc F Delvigne JP Lecomte P Thonart 2006 Foam control in fermentation bioprocess: from simple aeration tests to bioreactor Appl Biochem Biotechnol 129-132 392 404 16915656 10.1385/ABAB:130:1:392
P Fickers P-H Benetti Y Wache A Marty S Mauersberger MS Smit J-M Nicaud 2005 Hydrophobic substrate utilisation by the yeast Yarrowia lipolytica and its potential applications FEMS Yeast Res 5 527 543 15780653 10.1016/j.femsyr.2004. 09.004 1:CAS:528:DC%2BD2MXisVChu7w%3D
P Fickers J Destain P Thonart 2005 Methyl oleate modulates LIP2 expression in the lipolytic yeast Yarrowia lipolytica Biotechnol Lett 27 1751 1754 16314965 10.1007/s10529-005-3547-2 1:CAS:528:DC%2BD2MXht1Gqu7zL
ME Guerzoni R Lanciotti L Vannini F Galgano F Favati F Gardini G Suzzi 2001 Variability of the lipolytic activity in Yarrowia lipolytica and its dependence on environmental conditions Int J Food Microbiol 69 79 89 11589563 10.1016/S0168-1605(01)00575-X 1:CAS:528:DC%2BD3MXmsFentro%3D
B Junker 2004 Scale-up methodologies for Escherichia coli and yeast fermentation processes J Biosci Bioeng 97 6 347 364 16233642 1:CAS:528:DC%2BD2cXmvFehsL0%3D
B Junker 2007 Foam and its mitigation in fermentation systems Biotechnol Prog 23 767 784 17567037 1:CAS:528:DC%2BD2sXmtlGgu7s%3D
T Kar F Delvigne M Masson J Destain P Thonart 2008 Investigation of the effect of different extracellular factors on the lipase production by Yarrowia lipolityca on the basis of a scale-down approach J Ind Microbiol Biotechnol 35 9 1053 1059 18546026 10.1007/s10295-008-0382-1 1:CAS:528:DC%2BD1cXhtVSrsr%2FO
T Kar J Destain P Thonart F Delvigne 2010 Impact of scaled-down on dissolved oxygen fluctuations at different levels of the lipase synthesis pathway of Yarrowia lipolytica Biotechnol Agron Soc Environ 14 2 523 529 1:CAS:528:DC%2BC3MXjtFKgug%3D%3D
AR Lara E Galindo OT Ramirez LA Palomares 2006 Living with heterogeneities in bioreactors Mol Biotechnol 34 3 355 381 17284782 10.1385/MB:34:3:355 1:CAS:528:DC%2BD28XhtlWktrvO
S Mansour J Bailly J Delettre P Bonnarme 2009 A proteomic and transcriptomic view of amino acids catabolism in the yeast Yarrowia lipolytica Proteomics 9 20 4714 4725 19764064 10.1002/pmic.200900161 1:CAS:528: DC%2BD1MXht1Ort7vP
S Müller H Harms T Bley 2010 Origin and analysis of microbial population heterogeneity in bioprocesses Curr Opin Biotechnol 21 100 113 20138500 10.1016/j.copbio.2010.01.002
P Neubauer S Junne 2010 Scale-down simulators for metabolic analysis of large-scale bioprocesses Curr Opin Biotechnol 21 114 121 20185293 10.1016/j.copbio.2010.02.001 1:CAS:528:DC%2BC3cXjslSjtL0%3D
PR Patnaik 2006 External, extrinsic and intrinsic noise in cellular systems: analogies and implications for protein synthesis Biotechnol Mol Biol Rev 1 4 121 127
F Vardar-Sukan 1998 Foaming: consequences, prevention and destruction Biotechnol Adv 16 5/6 913 948 10.1016/S0734-9750(98)00010-X 1:CAS:528: DyaK1cXmtlCnu7s%3D
P Vrabel RGJM van der Lans KCAM Luyben L Boon AN Nienow 2000 Mixing in large-scale vessels stirred with multiple radial or radial and axial up-pumping impellers: modelling and measurements Chem Eng Sci 55 5881 5896 10.1016/S0009-2509(00)00175-5 1:CAS:528:DC%2BD3cXot1OisLk%3D
J Zahradnik R Mann M Fialova D Vlaev SD Vlaev V Lossev P Seichter 2001 A network-of-zones analysis of mixing and mass transfer in three industrial bioreactors Chem Eng Sci 56 485 492 10.1016/S0009-2509(00)00252-9 1:CAS:528:DC%2BD3MXht1yktb4%3D
