Article (Scientific journals)
Structure of the Cell Wall of Staphylococcus Aureus, Strain Copenhagen. II. Separation and Structure of Disaccharides
Ghuysen, Jean-Marie; Strominger, Jack L.
1963In Biochemistry, 2, p. 1119-1125
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Keywords :
amino acids; chemical phenomena; chemistry; disaccharides; staphylococcus; streptomyces
Abstract :
[en] The disaccharides, β-1,6-N-acetylglucosamimyl-N-acetylmuramic acid and β-1,6-N-acetyl-glucosaminyl-N,4-O-diacetylmuramic acid, have been identified as products of hydrolysis of the cell wall of S. aureus by an acetylmuramidase and an amidase from Streptomyces albus G. N-acetylmuramic acid and N,4-O-diacetylmuramic acid were formed from these compounds after hydrolysis with a β-acetylglucosarninidase. The data obtained do not exclude the presence of a small percentage of disaccharides with other linkages, however. Several bases for the resistance of cell walls of S. aureus to hydrolysis by egg white lysozyme have been discussed.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Ghuysen, Jean-Marie ;  Université de Liège - ULiège > Service de Batériologie
Strominger, Jack L.;  Washington University School of Medecine > Service of Pharmacology
Language :
English
Title :
Structure of the Cell Wall of Staphylococcus Aureus, Strain Copenhagen. II. Separation and Structure of Disaccharides
Publication date :
01 September 1963
Journal title :
Biochemistry
ISSN :
0006-2960
eISSN :
1520-4995
Publisher :
American Chemical Society, Washington, United States - District of Columbia
Volume :
2
Pages :
1119-1125
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
NSF - National Science Foundation [US-VA]
U.S. Public Health Service - United States Public Health Service
Available on ORBi :
since 07 July 2011

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