Reference : Mapping and polymorphism of bovine ghreline gene
Scientific congresses and symposiums : Poster
Life sciences : Genetics & genetic processes
Life sciences : Animal production & animal husbandry
http://hdl.handle.net/2268/70275
Mapping and polymorphism of bovine ghreline gene
English
Colinet, Frédéric mailto [Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > > Biologie animale et microbienne > >]
Eggen, André [Institut Scientifique de Recherche Agronomique - INRA > > Laboratoire de Génétique Biochimique et Cytogénétique (LGBC - UR339) > >]
Halleux, Caroline [Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > > Biologie animale et microbienne > >]
Arnould, Valérie mailto [Faculté Universitaire des Sciences Agronomiques de Gembloux - FUSAGx > > Biologie animale et microbienne > >]
Portetelle, Daniel mailto [Université de Liège - ULiège > Chimie et bio-industries > Biologie animale et microbienne >]
Renaville, Robert mailto [Université de Liège - ULiège > Chimie et bio-industries > Biologie animale et microbienne >]
Aug-2006
A0
No
No
International
30th Conference of the International Society of Animal Genetics
du 20 août 2006 au 25 août 2006
Colégio Brasileiro de Reprodução Animal
Porto Seguro
Brésil
[en] Ghrelin ; Mapping ; Polymorphism
[en] Bovine ghrelin, a 27-amino-acid peptide has been identified in bovine oxyntic
glands of the abomasum. It is an endogenous growth hormone secretagogue.
Total mRNA was extracted from abomasum and complete ghrelin mRNA was
sequenced by rapid amplification of cDNA ends. The gene contains five exons
and four introns with a short noncoding first exon of 17 bp similar to mouse and
human ghrelin gene. Using a radiation hybrid panel, the gene was mapped to
chromosome 22 near microsatellite markers UWCA49, BM4102, BMS1932,
BM2613 and URB035 with good LOD Score. Some studies detected different
QTLs near these markers like for milk fat percent, milk protein percent and
somatic cell score. So, it would be interesting to study the polymorphism on
the bovine ghrelin gene. Screening for polymorphisms in the five exons and the
introns II and IV on ten Belgian Blue bulls, ten Holsteins bulls and ten
Limousin bulls revealed a total of three single nucleotide polymorphisms. In
order to evaluate if ghrelin could be involved in genetic variation for milk fat
percent, milk protein percent and somatic cell score an association study
between SNPs on ghrelin gene and these traits could be performed in a major
cattle population.
Researchers
http://hdl.handle.net/2268/70275

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
ISAG 2006 Poster_Colinet_F.pdfAuthor postprint177.54 kBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.