[en] The gene encoding the extracellular, active-site serine beta-lactamase of Actinomadura R39, previously cloned into Streptomyces lividans, has the information for the synthesis of a 304 amino acid protein, the amino terminal region of which has the characteristic features of a signal peptide. The Actinomadura R39 beta-lactamase is another member of the class A beta-lactamases. In particular, it shows high homology with the beta-lactamase of Bacillus licheniformis.
Disciplines :
Microbiology
Author, co-author :
Houba, Simone; Université de Liège - ULiège > Institut de Chimie > Service de Microbiologie
Willem, Sabine; Université de Liège - ULiège > Institut de Chimie > Service de Microbiologie
Duez, Colette ; Université de Liège - ULiège > Institut de Chimie > Service de Microbiologie
Molitor, Chantal; Université de Liège - ULiège > Institut de chimie > Service de Microbiologie
Dusart, Jean; Université de Liège - ULiège > Institut de chimie > Service de Microbiologie
Frère, Jean-Marie ; Université de Liège - ULiège > Institut de chimie > Service de Microbiologie
Ghuysen, Jean-Marie ; Université de Liège - ULiège > Institut de chimie > Service de Microbiologie
Language :
English
Title :
Nucleotide sequence of the gene encoding the active-site serine β-lactamase from Actinomadura R39
Publication date :
December 1989
Journal title :
FEMS Microbiology Letters
ISSN :
0378-1097
eISSN :
1574-6968
Publisher :
Oxford University Press, United Kingdom
Volume :
65
Issue :
3
Pages :
241-246
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
FRSM - Fonds de la Recherche Scientifique Médicale
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