Article (Scientific journals)
Report of a case of Streptococcus agalactiae mycotic aneurysm and review of the literature.
Chandrikakumari, Kavitha; Giot, Jean-Baptiste; de Leval, Laurence et al.
2008In International Journal of Surgical Pathology, 16 (3), p. 314-9
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Keywords :
Aged; Aneurysm, Infected/diagnosis/microbiology/therapy; Anti-Infective Agents/therapeutic use; Aorta, Abdominal/microbiology/pathology/surgery; Aortic Aneurysm, Abdominal/microbiology/pathology/therapy; Aza Compounds/therapeutic use; Humans; Male; Quinolines/therapeutic use; Streptococcal Infections/complications/pathology/therapy; Streptococcus agalactiae/isolation & purification; Tomography, X-Ray Computed; Treatment Outcome
Abstract :
[en] A unique case of mycotic aneurysm of the abdominal aorta caused by Streptococcus agalactiae in an afebrile patient presenting with abdominal pain is described. Although this bacterium is associated with a variety of infections in human beings, aortitis is uncommon. Chronic alcoholism and diabetes mellitus are the 2 major predisposing conditions for group B Streptococci infection and both were present in this case. The abdominal pain and elevated inflammatory markers in the absence of fever were elusive in presentation; however, the diagnosis of mycotic aneurysm was established by abdominal computed tomography scan. The patient was treated successfully by resection of the diseased aorta and aortic allograft replacement. Culture of the excised tissue grew Streptococcus agalactiae sensitive to penicillin G and (other commonly tested antibiotics) fluoroquinolones. A prolonged course of moxifloxacin (for 6 months) was administered due to the persistence of elevated inflammatory markers and was remarkably well tolerated. Sixteen months after stopping the antibiotics, the patient is doing well, and the control imaging studies are satisfactory.
Disciplines :
Immunology & infectious disease
Author, co-author :
Chandrikakumari, Kavitha;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
Giot, Jean-Baptiste ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
de Leval, Laurence ;  Centre Hospitalier Universitaire de Liège - CHU > Anatomie pathologique
Creemers, Etienne ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire
Leonard, Philippe ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale
Mukeba, Didier
Moutschen, Michel  ;  Université de Liège - ULiège > Département des sciences cliniques > Immunopathologie - Transplantation
Frippiat, Frédéric  ;  Centre Hospitalier Universitaire de Liège - CHU > Maladies infectieuses et médecine interne générale - Direction médicale
Language :
English
Title :
Report of a case of Streptococcus agalactiae mycotic aneurysm and review of the literature.
Publication date :
2008
Journal title :
International Journal of Surgical Pathology
ISSN :
1066-8969
Publisher :
Westminster Publications, Glen Head, United States - New York
Volume :
16
Issue :
3
Pages :
314-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 January 2009

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