METZOON : Development of a quantitative microbial risk assessment for human salmonellosis through household consumption of fresh minced pork méat in Belgium.
[en] A quantitative microbial risk assessment according to the Codex Alimentarius Principles is conducted
to evaluate the risk on human salmonellosis through household consumption of fresh
minced pork meat in Belgium. The quantitative exposure assessment is carried out by building
a modular risk model, called the METZOON-model, which covers the pork production
from farm to fork. In the METZOON-model, the food production pathway is split up in six
consecutive modules: (1) primary production, (2) transport & lairage, (3) slaughterhouse, (4)
post-processing, (5) distribution & storage and (6) preparation & consumption. All the modules
are developed to resemble as closely as possible the Belgian situation making use of the
available national data. Several statistical refinements and improved modeling techniques are
proposed. The model produces highly realistic results. The baseline predicted number of annual
salmonellosis cases is 20513 [st. dev. 9061.45]. The risk is estimated higher for the susceptible
population [est. 4.713 × 10−5; st. dev. 1.466 × 10−5] compared to the normal population [est.
7.704 × 10−6; st. dev. 5.414 × 10−6] and is mainly due to cross contamination via cook’s hands
and only for a small extent to undercooking.
Disciplines :
Microbiology
Author, co-author :
Bollaerts, Kaatje; Universiteit Hasselt - UH
Messens, Winy; Instituut voor Landbouw- en Visserijonderzoek = Institute for Agricultural and Fisheries Research
Delhalle, Laurent ; Université de Liège - ULiège > Département de sciences des denrées alimentaires > Microbiologie des denrées alimentaires
Aerts, Marc; Universiteit Hasselt - UH
Van de Stede, Yves; Centre d'Etudes et de Recherches Vétérinaires Agronomiques = Centrum voor Onderzoek in Diergeneeskunde en Agrochemie - CERVA=CODA
Dewulf, Jeroen; Universiteit Gent - Ugent
de Busser, Elisabeth; Universiteit Gent - Ugent
Daube, Georges ; Université de Liège - ULiège > Département de sciences des denrées alimentaires > Microbiologie des denrées alimentaires
Maes, Dominique; Universiteit Gent - Ugent
Mintiens, Koen; Centre d'Etudes et de Recherches Vétérinaires Agronomiques = Centrum voor Onderzoek in Diergeneeskunde en Agrochemie - CERVA=CODA
Grijspeerdt, Koen; Instituut voor Landbouw- en Visserijonderzoek = Institute for Agricultural and Fisheries Research
Language :
English
Title :
METZOON : Development of a quantitative microbial risk assessment for human salmonellosis through household consumption of fresh minced pork méat in Belgium.
Publication date :
2009
Journal title :
Risk Analysis
ISSN :
0272-4332
eISSN :
1539-6924
Publisher :
Blackwell Publishing, Malden, United States - Massachusetts
Volume :
29
Issue :
6
Pages :
820-840
Peer reviewed :
Peer Reviewed verified by ORBi
Name of the research project :
METZOON
Funders :
SPF Santé - Service Public Fédéral Santé publique. Sécurité de la Chaîne alimentaire et Environnement
(2003) Official Journal of the European Union, , Directive 2003/99/EC of the European Parliament and of the Council of 17 November 2003 on the monitoring of zoonoses and zoonotic agents, amending Council Decision 90/424/EEC and repealing Council Directive 92/117/EEC. 12.12.2003. L 325/31
Collard, J.M., Bertrand, S., Dierick, K., Godard, C., Wildemauve, G., Vermeersch, K., Duculot, J., Quinet, C., Drastic decrease in Salmonella enteritidis isolated from humans in Belgium in 2005, shift in phage types and influence on foodborne outbreaks (2008) Epidemiological Infection, 136, pp. 771-781
Trends and sources of zoonoses, zoonotic agents and antimicrobial resistance in the European Union in 2004 (2004) EFSA Journal, 310, pp. 1-278. , European Food Safety Authority
(2009) EFSA Journal, 310, pp. 1-278. , The Community Summary report on trends and sources of zoonoses, zoonotic agents and antimicrobial resistance in the European Union in 2007
Official Journal of the European Union, p. 12122003. , Regulation (EC) No 2160/2003 of the European Parliament and of the Council of 17 November 2003 on the control of Salmonella and other specified food-borne zoonotic agents. 2003, L 325/1
Boone, I., Van Der Stede, Y., Bollaerts, K., Vose, D., Maes, D., Dewulf, J., Daube, G., Mintiens, K., NUSAP method for evaluating the data quality in a quantitative microbial risk assessment model for Salmonella in the pork production chain (2009) Risk Analysis, 29, pp. 502-517. , DOI:
Boone, I., Van Der Stede, Y., Bollaerts, K., Messens, W., Vose, D., Daube, G., Aerts, M., Mintiens, K., Expert Judgement in A Risk Assessment Model for Salmonella Spp. in Pork: On the Performance of Different Weighting Schemes, , Preventive Veterinary Medicine
Bollaerts, K., Aerts, M., Faes, C., Grijspeerdt, K., Dewulf, J., Mintiens, K., Human salmonellosis: Estimation of dose-illness form outbreak data (2008) Risk Analysis, 28, pp. 427-440
Bollaerts, K., Aerts, M., Ribbens, S., Van Der Stede, Y., Boone, I., Mintiens, K., Identification of Salmonella high risk pig herds in Belgium using semi-parametric quantile regression (2008) Journal of Royal Statistical Society, Series A, 171, pp. 1-16
Delhalle, L., Desadeleer, L., Bollaerts, K., Farnir, F., Saegerman, C., Korsak, N., De Zutter, L., Daube, G., Exploration of the risk factors for Salmonella and hygiene indicators in the ten largest Belgian pig slaughterhouses (2008) Journal of Food Protection, 71, pp. 1320-1329
Delhalle, L., Saegerman, C., Farnir, F., Korsak, N., Maes, D., Messens, W., De Zutter, L., Daube, G., Salmonella surveillance and control in the post-harvest pork meat chain (2009) Food Microbiology, 26, pp. 265-271
De Busser, E.V., Dewulf, J., Nollet, N., Houf, K., Schwarzer, K., De Sadeleer, L., De Zutter, L., Maes, D., Effect of organic acids in drinking water during the last two weeks prior to slaughter on Salmonella shedding by slaughter pigs and contamination of carcasses (2009) Zoonosis and Public Health, 56, pp. 129-136
Hill, A.A., England, T.J., Snary, E.L., Kelly, L.A., Cook, A.J.C., Wooldridge, M., (2003) A "farm-to-consumption" Risk Assessment for the Adverse Effects to Human Health of Salmonella Typhimurium in Pigs, , Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency. UK report
Van Der Gaag, M.A., (2004) Epidemiological and Economic Simulation of Salmonella Control in the Pork Supply Chain, , PhD thesis. Wageningen, The Netherlands
Alban, L., Stark, K.D.C., Where should the effort be put to reduce the Salmonella prevalence in the slaughtered swine carcass effectively? (2005) Preventive Veterinary Medicine, 68 (1), pp. 63-79. , DOI 10.1016/j.prevetmed.2005.01.001
Ranta, J., Tuominen, P., Rautiainen, E., Miajala, R., (2004) Salmonella in Pork Production in Finland - A Quantitative Risk Assessment., , National Veterinary and Food Research Institute, EELA. Finland report
Nauta, M.J., Microbiological risk assessment models for partitioning and mixing during food handling (2005) International Journal of Food Microbiology, 100 (1-3), pp. 311-322. , DOI 10.1016/j.ijfoodmicro.2004.10.027, Fourth International Conference on Predictive Modelling in Foods
(1999) Principles and Guidelines for the Conduct of Microbiological Risk Assessment, , Codex Alimentarius Commission
Section de bactériologie, Centre National de Réfé rence des Salmonella et des Shigella (2006) Rapport Annuel des Souches de Salmonella et Shigella Isolées en Belgique en, , Scientific Institute of Public Health
Mead, P.S., Slutsker, L., Dietz, V., McCaig, L.F., Bresee, J.S., Shapiro, C., Griffin, P.M., Tauxe, R.V., Food-related illness and death in the United States (1999) Emerging Infectious Diseases, 5 (5), pp. 607-625
Van Pelt, W., Van De Giessen, A.W., Van Leeuwen, W.J., Wannet, W., Henken, A.M., Evers, E.G., De Wit, M.A., Van Duynhoven, Y.T., Deel 1: Oorsprong, omvang en kosten van humane salmonellose met betrekking tot varken, rund, kip, ei en overige bronnen (1999) Infectious Bulletin, 10, pp. 240-243
Walker, W.E., Harremoës, P., Rotmans, J., Van Der Sluis, J.P., Van Asselt, M.B.A., Janssen, P., Krayer Von Krauss, M.P., Defining uncertainty - A conceptual basis for uncertainty management in model-based decision support (2003) Integrated Assessment, 4 (1), pp. 5-17
Devriese, S., Huybrechts, I., Moreau, M., Van Oyen, H., De Belgische voedselconsumptiepeiling 1 - 2004 (2006) Afdeling Epidemiologie, , Wetenschappelijk Instituut Volksgezondheid. Belgium report
Van Der Stede, Y., Boone, I., Bollaerts, K., Herr, C., Abrahantes, K.J.C., Aerts, M., Hooyberghs, J., Mintiens, K., (2008) Implementing A Salmonella Surveillance Program in Belgian Pig Herds, , Working paper
Ribbens, S., Dewulf, J., Maes, D., Koenen, F., Mintiens, K., Desadeleer, L., Kruif, A., A survey on biosecurity and management practices in Belgian pig herds (2008) Preventive Veterinary Medicine, 83, pp. 228-241
Eilers, P.H.C., Marx, B.D., Flexible smoothing using B-splines and penalized likelihood (with comments and rejoinder) (1996) Statistical Science, 11, pp. 89-121
Berends, B.R., Van Knapen, F., Snijders, J.M.A., Mossel, D.A.A., Identification and quantification of risk factors regarding Salmonella spp. on pork carcasses (1997) International Journal of Food Microbiology, 36 (2-3), pp. 199-206. , DOI 10.1016/S0168-1605(97)01267-1, PII S0168160597012671
Nollet, N., Maes, D., Duchateau, L., Hautekiet, V., Houf, K., Van Hoof, J., De Zutter, L., Geers, R., Discrepancies between the isolation of Salmonella from mesentric lymph nodes and the results of serological screening in slaughter pigs (2005) Veterinary Research, 36 (4), pp. 545-555. , DOI 10.1051/vetres:2005014
Botteldoorn, N., Heyndrickx, M., Rijpens, N., Grijspeerdt, K., Herman, L., Salmonella on pig carcasses: Positive pigs and cross contamination in the slaughterhouse (2003) Journal of Applied Microbiology, 95 (5), pp. 891-903. , DOI 10.1046/j.1365-2672.2003.02042.x
Molenberghs, G., Verbeke, G., (2005) Models for Discrete Longitudinal Data., , New York. Springer
Swanenburg, M., Urlings, H.A.P., Keuzenkamp, D.A., Snijders, J.M.A., Salmonella in the lairage of pig slaughterhouses (2001) Journal of Food Protection, 64 (1), pp. 12-16
Berends, B.R., Urlings, H.A.P., Snijders, J.M.A., Van Knapen, F., Identification and quantification of risk factors in animal management and transport regarding Salmonella spp. in pigs (1996) International Journal of Food Microbiology, 30 (1-2), pp. 37-53. , DOI 10.1016/0168-1605(96)00990-7
Davies, R.H., McLaren, I.M., Bedford, S., (1999) Distribution of Salmonella Contamination in Two Pig Abattoirs, , Pp. 267 - 272 inProceedings 3rd International Symposium on the Epidemiology and Control of Salmonella in pork. Washington, DC: ISECP. August 5-7
Chang, V.P., Mills, E.W., Cutter, C.N., Reduction of bacteria on pork carcasses associated with chilling method (2003) Journal of Food Protection, 66 (6), pp. 1019-1024
Carr, M.A., Thompson, L.D., Miller, M.F., Boyd Ramsey, C., Kaster, C.S., Chilling and trimming effects on the microbial populations of pork carcasses (1998) Journal of Food Protection, 61 (4), pp. 487-489
Vose, D., (2000) Risk Analysis: A Quantitative Guide, 2nd Ed., , John Wiley & Sons. Chichester
Cahill, S., Risk assessments of Salmonella in eggs and broiler chickens (2002) FOOD NUTRITION AND AGRICULTURE, (31), pp. 62-70
Oscar, T.P., Response surface models for effects of temperature, pH, and previous growth pH on growth kinetics of Salmonella Typhimurium in brain heart infusion broth (1999) Journal of Food Protection, 62 (2), pp. 106-111
Delhalle, L., Farnir, F., Saegerman, C., De Sadeleer, L., De Zutter, L., Daube, G., Détermination des points critiques pour la contamination par Salmonella de la viande de porc lors de la découpe, le hachage et la distribution en Belgique Proceedings of Colloque d' Epidémiologie AEEMA., p. 134. , In. Liège. 2006
Regulation (EC) No 853/2004 of the European Parliament and of the Council of 29 April 2004 laying down specific hygiene rules for food of animal origin Official Journal of the European Union, p. 30042004. , 2004, L 139
Nauta, M.J., Evers, E.G., Takumi, K., Havelaar, A., Risk assessment of shiga-toxin producing Escherichia coli O157 in steak tartare in the Netherlands (2001) RIVM Report, Nr., pp. 1-169. , 257851003
Zout in de voeding (Salt in food products) (2008) Test Gezondheid, 65, pp. 15-19
Mylius, S.D., Nauta, M.J., Havelaar, A.H., Cross-contamination during food preparation: A mechanistic model applied to chicken-borne Campylobacter (2007) Risk Analysis, 27 (4), pp. 803-813. , DOI 10.1111/j.1539-6924.2006.00872.x
Montville, R., Chen, Y., Schaffner, D.W., Glove barriers to bacterial cross-contamination between hands to food (2001) Journal of Food Protection, 64 (6), pp. 845-849
Kusumaningrum, H.D., Van Asselt, E.D., Beumer, R.R., Zwietering, M.H., A quantitative analysis of cross-contamination of Salmonella and Campylobacter spp. via domestic kitchen surfaces (2004) Journal of Food Protection, 67 (9), pp. 1892-1903
Heymann, D.L., (2004) Control of Communicable Diseases Manual, 18th Ed., , Washington, DC: APHA
Hohmann, E.L., Nontyphoidal salmonellosis (2001) Clinical Infectious Diseases, 32 (2), pp. 263-269. , DOI 10.1086/318457
Teunis, P.F.M., Nagelkerke, N.J.D., Haas, C.N., Dose response models for infectious gastroenteritis (1999) Risk Analysis, 19 (6), pp. 1251-1260. , DOI 10.1023/A:1007055316559
Royston, P., Altman, D.G., Regression using fractional polynomials of continuous covariates: parsimonious parametric modelling (1994) Journal of the Royal Statistical Society. Series C: Applied Statistics, 43 (3), p. 429
Directorate General Statistics Belgium, , FPS Economy. Belgian population
A quantitative microbiological risk assessment on Salmonella in meat: Source attribution for human salmonellosis from meat (2008) EFSA Journal, 625, pp. 1-32
Hald, T., Vose, D., Wegener, H.C., Koupeev, T., A Bayesian Approach to Quantify the Contribution of Animal-Food Sources to Human Sahnonellosis (2004) Risk Analysis, 24 (1), pp. 255-269. , DOI 10.1111/j.0272-4332.2004.00427.x
Van Pelt, W., Valkenburgh, S.M., (2001) Zoonoses and Zoonotic Agents in Humans, Food, Animals and Feed in the Netherlands, , The Hague, KvW- Inspectorate for Health Protection and Veterinary Public Health
Berends, B.R., Van Knapen, F., Mossel, D.A.A., Burt, S.A., Snijders, J.M.A., Salmonella spp. on pork at cutting plants and at the retail level and the influence of particular risk factors (1998) International Journal of Food Microbiology, 44 (3), pp. 207-217. , DOI 10.1016/S0168-1605(98)00122-6, PII S0168160598001226
Hurd, H.S., McKean, J.D., Wesley, I.V., Karriker, L.A., The effect of lairage on Salmonella isolation from market swine (2001) Journal of Food Protection, 64 (7), pp. 939-944
Boudry, C., Korsak, N., Jacob, B., Etienne, G., Thewis, A., Daube, G., Ecology of Salmonella in slaughter pigs digestive tract and study of the contamination of carcasses (2002) Annales de Medecine Veterinaire, 146 (6), pp. 353-360
(2007) Federal Agency for the Safety of the Food Chain, pp. 1-186. , Activity report 2006. FAVV Report
(2008) EFSA Journal, pp. 1-111. , Report of the task force on zoonoses data collection on the analysis of the baseline survey on the prevalence of Salmonella in slaughter pigs, part a
Korsak, N., Groven, B., Jacob, B., Daube, G., Flament, E., Prevalence of Salmonella along a meat pork production system (2002) Food Safety Assurance and Veterinary Public Health Food Safety Assurance in the Pre-harvest Phase, Vol. 1., , In. Smulders, F.J.M.*Collins J.D. eds). Wageningen. Academic Publishers
Saltelli, A., Sensitivity analysis for importance assessment (2002) Risk Analysis, 22 (3), pp. 579-590. , DOI 10.1111/0272-4332.00040
Directorate General Statistics Belgium, , FPS Economy. Animal slaughter in Belgium
(2003) Test Aankoop, 464, pp. 8-9. , Bewaartemperatuur voor voedingswaren (Storage temperature of food products)
Chen, Y., Jackson, K.M., Chea, F.P., Schaffner, D.W., Quantification and variability analysis of bacterial cross-contamination rates in common food service tasks (2001) Journal of Food Protection, 64 (1), pp. 72-80
Cogan, T.A., Slader, J., Bloomfield, S.F., Humphrey, T.J., Achieving hygiene in the domestic kitchen: The effectiveness of commonly used cleaning procedures (2002) Journal of Applied Microbiology, 92 (5), pp. 885-892. , DOI 10.1046/j.1365-2672.2002.01598.x
Halet, D., Viaene, J., Gellynck, X., (2006) Onderzoek Naar Het Consumentengedrag Tegenover Kip [consumer Behavior Towards Fresh Poultry Meat, , Department Agricultural Economics Report
