Ribes nigrum; Black Currant Leaves; prodelphinidins; anti-inflammatory activity; carrageenann model
Abstract :
[en] In a study to select anti-inflammatory medicinal plants, we have observed that extracts of Ribes nigrum significantly inhibited at a dose of 50mg/kg i.p. the carrageenan rat paw edema. We have now proved that the most active fractions contained proanthocyanidins . In the present study, we report on the isolation of three bioactive compounds: two prodelphinidins dimers and a new trimeric one.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Tits, Monique ; Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Damas, Jacques ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Dierckxsens, Yvan
Poukens, Pascale
Language :
English
Title :
Antiinflammatory Prodelphinidins from Black Currant (Ribes nigrum) Leaves
Publication date :
1991
Journal title :
Planta Medica
ISSN :
0032-0943
eISSN :
1439-0221
Publisher :
Georg Thieme Verlag Stuttgart, New York, United States - New York
