Article (Scientific journals)
Cloning and characterisation of the primary structure of the sheep lymphocyte function-associated antigen-1 alpha subunit
Fett, Thomas; Zecchinon, Laurent; Baise, Etienne et al.
2005In Molecular Immunology, 42 (12), p. 1503-1508
Peer Reviewed verified by ORBi
 

Files


Full Text
article sheep cd11a.pdf
Publisher postprint (464.19 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
integrin; LFA-1; ICAM; adhesion; ovine
Abstract :
[en] The leukocyte integrins play a critical role in a number of cellular adhesive interactions during the immune response. The ovine cDNA encoding CD1 1a, the predominant a subunit of the beta(2)-integrin family, was sequenced and compared with the human, bovine and murine sequences. Despite some focal differences, it shares all the main characteristics of its known mammalian homologues. Along with the ovine CD18-encoding cDNA, which is available for a few months, the sequence data provided here will allow the Ovis aries beta(2)-integrin CD1 1a/CD18 (LEA-1, alpha(L)beta 2) expression in vitro as a tool to examine the specificities of inflammation in the ovine species. (c) 2005 Elsevier Ltd. All rights reserved.
Disciplines :
Biochemistry, biophysics & molecular biology
Immunology & infectious disease
Author, co-author :
Fett, Thomas ;  Université de Liège - ULiège > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies
Zecchinon, Laurent ;  Université de Liège - ULiège > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies
Baise, Etienne ;  Université de Liège - ULiège > Département des sciences de la vie > Macromolécules biologiques
Desmecht, Daniel ;  Université de Liège - ULiège > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies
Language :
English
Title :
Cloning and characterisation of the primary structure of the sheep lymphocyte function-associated antigen-1 alpha subunit
Publication date :
2005
Journal title :
Molecular Immunology
ISSN :
0161-5890
Publisher :
Pergamon-Elsevier Science Ltd, Oxford, United Kingdom
Volume :
42
Issue :
12
Pages :
1503-1508
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 January 2010

Statistics


Number of views
40 (1 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
7
Scopus citations®
without self-citations
2
OpenCitations
 
5

Bibliography


Similar publications



Contact ORBi