Microwave-assisted extraction

Ferrara, Donatella; Purcaro, Giorgia

doi:10.1016/B978-0-443-15978-7.00099-0

No full text

Contribution to collective works (Parts of books)

Microwave-assisted extraction

Ferrara, Donatella; Purcaro, Giorgia

2025 • In Comprehensive Sampling and Sample Preparation

Peer reviewed

Permalink
https://hdl.handle.net/2268/348089

DOI
10.1016/B978-0-443-15978-7.00099-0

Files (0)Send to Details Statistics Bibliography Similar publications

Files

Full Text

No document available.

Send to

RIS BibTex APA Chicago Permalink X Linkedin

Details

Keywords :

Applications; Atmospheric microwave extraction; Clinical analysis; Environmental analysis; Food analysis; Green Chemistry; Method Optimization; Microwave-assisted extraction; Standard methods; Green-chemistry; Method optimization; Microwave extraction; Optimisations; Standard method; Chemistry (all)

Abstract :

[en] This chapter provides an overview of the principle of microwave-assisted extraction in different fields of applications. A brief introduction to the historical development of microwave is provided before entering more technical aspects related the laboratory instruments (configuration of the equipment, such as magnetron, waveguides, resonance cavities, etc.) and the important parameters in method optimization (i.e., solvent selection, sample size, extraction time and temperature). The main advantages of microwave-assisted extraction are explained and highlighted in different fields of application, namely environmental, food, and clinical analysis. Finally, the role of microwave-assisted extraction in the perspective of green chemistry will be discussed.

Disciplines :

Chemistry
Food science

Author, co-author :

Ferrara, Donatella ; Université de Liège - ULiège > TERRA Research Centre

Purcaro, Giorgia ; Université de Liège - ULiège > Département GxABT > Chemistry for Sustainable Food and Environmental Systems (CSFES)

Language :

English

Title :

Microwave-assisted extraction

Publication date :

2025

Main work title :

Comprehensive Sampling and Sample Preparation

Publisher :

Elsevier

ISBN/EAN :

978-0-443-15978-7
978-0-443-15979-4

Peer reviewed :

Peer reviewed

Additional URL :

https://api.elsevier.com/content/article/PII:B9780443159787000990?httpAccept=text/xml

Available on ORBi :

since 23 August 2026

Statistics

Number of views

31 (0 by ULiège)

Number of downloads

0 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenAlex citations

Bibliography

Veronesi, P. An introduction to dielectric heating. In Microwave Chemistry; De Gruyter, 2017; pp 18–30. doi:10.1515/9783110479935-002.
Abu-Samra, A.; Steven Morris, J.; Koirtyohann, S. R. Wet Ashing of Some Biological Samples in a Microwave Oven. J. Am. Water Works Assoc 1971, 67(2), 1.
Giguere, R. J.; Bray, T. L.; Duncan, S. M.; Majctich, G. Application of commercial microwave ovens to organic synthesis. Tetrahedron Letters 1986, 27(41), 4945–4948.
Ganzler, K.; Valko, K. Microwave extraction: A novel sample preparation method for chromatography. Journal of Chromatography 1986, 371, 299–306.
Jacob, J.; Chia, L. H. L.; Boey, F. Y. C. Thermal and non-thermal interaction of microwave radiation with materials. Journal of material science 1995, 30, 5321–5327.
Eskilsson, C.; Bjorklund, E. Analytical-scale microwave-assisted extraction. Journal of Chromatography A 2000, 902, 227–250.
Mello, P. A.; Barin, J. S.; Guarnieri, R. A. Microwave Heating. In Microwave-Assisted Sample Preparation for Trace Element Determination; Elsevier B.V., 2014; pp 59–75. doi:10.1016/B978-0-444-59420-4.00002-7.
Atuonwu, J. C.; Tassou, S. A. Energy issues in microwave food processing: A review of developments and the enabling potentials of solid-state power delivery. Critical Reviews in Food Science and Nutrition. Taylor and Francis Inc. May 15, 2019, pp 1392–1407. doi:10.1080/10408398.2017.1408564.
Moret, S.; Conchione, C.; Srbinovska, A.; Lucci, P. Microwave-based technique for fast and reliable extraction of organic contaminants from food, with a special focus on hydrocarbon contaminants. Foods 2019, 8(503). doi:10.3390/foods8100503.
de Castro, M. D. L.; Castillo-Peinado, L. S. Microwave-Assisted Extraction of Food Components. In Innovative Food Processing Technologies: Extraction, Separation, Component Modification and Process Intensification; Elsevier Inc., 2016; pp 57–110. doi:10.1016/B978-0-08-100294-0.00003-1.
Environmental Protection Agency (1997) Test methods for evaluating solid waste. Physical/chemical methods EPA SE-846 [version 2 (December 1997), integrated manual through update III]. Washington, DC.
Bélanger, J. M. R.; Paré, J. R. J. Applications of microwave-assisted processes (MAPTM™) to environmental analysis. Analytical and Bioanalytical Chemistry. 2006, pp 1049–1058. doi:10.1007/s00216-006-0766-x.
Sanchez-Prado, L.; Garcia-Jares, C.; Dagnac, T.; Llompart, M. Microwave-assisted extraction of emerging pollutants in environmental and biological samples before chromatographic determination. TrAC - Trends in Analytical Chemistry. Elsevier B.V. September 1, 2015, pp 119–143. doi:10.1016/j.trac.2015.03.014.
Paré, J. R. J.; Bélanger M.R. Microwave-Assisted Process (MApTM) : Principles and Applications. In Instrumental Methods in Food Analysis; 1997; pp 395–420.
Ferrara, D.; Beccaria, M.; Cordero, C. E.; Purcaro, G. Microwave-assisted extraction in closed vessel in food analysis. Journal of Separation Science 2023. doi:10.1002/jssc.202300390.
Wang, H.; Ding, J.; Ren, N. Recent advances in microwave-assisted extraction of trace organic pollutants from food and environmental samples. TrAC - Trends in Analytical Chemistry. Elsevier B.V. January 1, 2016, pp 197–208. doi:10.1016/j.trac.2015.05.005.
Bravo, L.; Mateos, R. Analysis of Flavonoids in Functional Foods and Nutraceuticals. In Methods of Analysis for Functional Foods and Nutraceuticals. W. Jeffrey Hurst, Ed.; Taylor & Francis Group, 2008; pp 148–193.
Yang, Z.; Zhai, W. Optimization of microwave-assisted extraction of anthocyanins from purple corn (Zea mays L.) cob and identification with HPLC-MS. Innovative Food Science and Emerging Technologies 2010, 11(3), 470–476. doi:10.1016/j.ifset.2010.03.003.
Mollica, A.; Locatelli, M.; Macedonio, G.; Carradori, S.; Sobolev, A. P.; De Salvador, R. F.; et al. Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars. Journal of Enzyme Inhibition and Medicinal Chemistry 2016, 31(S4), 1–6. doi:10.1080/14756366.2016.1214951.
Hiranvarachat, B.; Devahastin, S.; Chiewchan, N.; Vijaya Raghavan, G. S. Structural modification by different pretreatment methods to enhance microwave-assisted extraction of β-carotene from carrots. Journal of Food Engineering 2013, 115(2), 190–197. doi:10.1016/j.jfoodeng.2012.10.012.
Manirakiza, P.; Covaci, A.; Schepens, P. Comparative Study on Total Lipid Determination using Soxhlet, Roese-Gottlieb, Bligh & Dyer, and Modified Bligh & Dyer Extraction Methods. Journal of Food Composition and Analysis 2001, 14(1), 93–100. doi:10.1006/jfca.2000.0972.
Tsukui, A.; Santos Júnior, H. M.; Oigman, S. S.; De Souza, R. O. M. A.; Bizzo, H. R.; Rezende, C. M. Microwave-assisted extraction of green coffee oil and quantification of diterpenes by HPLC. Food Chemistry. Elsevier Ltd December 1, 2014, pp 266–271. doi:10.1016/j.foodchem.2014.05.039.
Bligh E.G.; Dyer W.J. A rapid method of total lipid extraction and purification. Canadian Journal of Biochemistry and Physiology 1959, 37(8).
Pati, S.; Nie, B.; Arnold, R. D.; Cummings, B. S. Extraction, chromatographic and mass spectrometric methods for lipid analysis. Biomedical Chromatography 2016, 30(5), 695–709. doi:10.1002/bmc.3683.
Dai, Y. M.; Chen, K. T.; Chen, C. C. Study of the microwave lipid extraction from microalgae for biodiesel production. Chemical Engineering Journal 2014, 250, 267–273. doi:10.1016/j.cej.2014.04.031.
Abdulkadir, S.; Tsuchiya, M. One-step method for quantitative and qualitative analysis of fatty acids in marine animal samples. Journal of Experimental Marine Biology and Ecology 2008, 354(1), 1–8. doi:10.1016/j.jembe.2007.08.024.
Cruz-Hernandez, C.; Hill, A. R.; Yurawecz, M. P.; Delmonte, P.; Mossoba, M. M.; Dugan, M. E. R.; et al. Methods for Analysis of Conjugated Linoleic Acids and trans-18:1 Isomers in Dairy Fats by Using a Combination of Gas Chromatography, Silver-Ion Thin-Layer Chromatography/Gas Chromatography, and Silver-Ion Liquid Chromatography. JOURNAL OF AOAC INTERNATIONAL 2004, 87(2), 545.
AOCS, Official Method Ce 2b-11. Direct Methylation of LIpids in Foods by Alkali Hydrolysis; Urbana, USA, 2017.
Souza, H. A. L.; Mariutti, L. R. B.; Bragagnolo, N. Microwave assisted direct saponification for the simultaneous determination of cholesterol and cholesterol oxides in shrimp. Journal of Steroid Biochemistry and Molecular Biology. Elsevier Ltd May 1, 2017, pp 88–95. doi:10.1016/j.jsbmb.2016.03.027.
Purcaro, G.; Barp, L.; Moret, S. Determination of hydrocarbon contamination in foods. A review. Analytical Methods. Royal Society of Chemistry, 2016, pp 5755–5772. doi:10.1039/c6ay00655h.
Pena, T.; Pensado, L.; Casais, C.; Mejuto, C.; Phan-Tan-Luu, R.; Cela, R. Optimization of a microwave-assisted extraction method for the analysis of polycyclic aromatic hydrocarbons from fish samples. Journal of Chromatography A 2006, 1121(2), 163–169. doi:10.1016/j.chroma.2006.04.038.
Akpambang, V. O. E.; Purcaro, G.; Lajide, L.; Amoo, I. A.; Conte, L. S.; Moret, S. Determination of polycyclic aromatic hydrocarbons (PAHs) in commonly consumed Nigerian smoked/grilled fish and meat. Food Additives and Contaminants - Part A 2009, 26(7), 1096–1103. doi:10.1080/02652030902855406.
Menegoz Ursol, L.; Conchione, C.; Srbinovska, A.; Moret, S. Optimization and validation of microwave assisted saponification (MAS) followed by epoxidation for high-sensitivity determination of mineral oil aromatic hydrocarbons (MOAH) in extra virgin olive oil. Food Chemistry 2022, 370, 1–9. doi:10.1016/j.foodchem.2021.130966.
Ana, S.; Chiara, C.; Fabiola, C.; Luca, M. U.; Sabrina, M. High sensitivity determination of mineral oils and olefin oligomers in cocoa powder and related packaging: Method validation and market survey. Food Chemistry 2022, 396, 1–8. doi:10.1016/j.foodchem.2022.133686.
Barriada-Pereira, M.; González-Castro, M. J.; Muniategui-Lorenzo, S.; López-Mahía, P.; Prada-Rodríguez, D.; Fernández-Fernández, E. Determination of organochlorine pesticides in horticultural samples by microwave assisted extraction followed by GC-ECD. International Journal of Environmental Analytical Chemistry 2005, 85(4–5), 325–333. doi:10.1080/03067310500042251.
Paíga, P.; Morais, S.; Correia, M.; Alves, A.; Delerue-Matos, C. Screening of carbamates and ureas in fresh and processed tomato samples using microwave-assisted extraction and liquid chromatography. Analytical Letters 2009, 42(2), 265–283. doi:10.1080/00032710802585717.
Fang, G.; Lau, H. F.; Law, W. S.; Li, S. F. Y. Systematic optimisation of coupled microwave-assisted extraction-solid phase extraction for the determination of pesticides in infant milk formula via LC-MS/MS. Food Chemistry 2012, 134(4), 2473–2480. doi:10.1016/j.foodchem.2012.04.076.
Fernández, P.; Seoane, S.; Vázquez, C.; Bermejo, A. M.; Carro, A. M.; Lorenzo, R. A. A rapid analytical method based on microwave-assisted extraction for the determination of drugs of abuse in vitreous humor. Analytical and Bioanalytical Chemistry 2011, 401(7), 2177–2186. doi:10.1007/s00216-011-5279-6.
Fernández, P.; Lago, M.; Lorenzo, R. A.; Carro, A. M.; Bermejo, A. M.; Tabernero, M. J. Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 2009, 877(18–19), 1743–1750. doi:10.1016/j.jchromb.2009.04.035.
Fernández, P.; Lago, M.; Lorenzo, R. A.; Carro, A. M.; Bermejo, A. M.; Tabernero, M. J. Microwave assisted extraction of drugs of abuse from human urine. J. Appl. Toxicol. 2007, 27, 373–379. doi:10.1002/jat.
Franke, M.; Winek, C. L.; Kingston, H. M. Iforensic Sciice Internatii Extraction of selected drugs from serum using microwave irradiation. Forensic Science International 1996, 81, 51–59.
Wietecha-Posłuszny, R.; Woźniakiewicz, M.; Garbacik, A.; Chesy, P.; Kościelniak, P. Application of microwave irradiation to fast and efficient isolation of benzodiazepines from human hair. Journal of Chromatography A 2013, 1278, 22–28. doi:10.1016/j.chroma.2013.01.005.
Jurowski, K.; Kochan, K.; Walczak, J.; Barańska, M.; Piekoszewski, W.; Buszewski, B. Comprehensive review of trends and analytical strategies applied for biological samples preparation and storage in modern medical lipidomics: State of the art. TrAC - Trends in Analytical Chemistry. Elsevier B.V., 2017, pp 276–289. doi:10.1016/j.trac.2016.10.014.
Teo, C. C.; Chong, W. P. K.; Tan, E.; Basri, N. B.; Low, Z. J.; Ho, Y. S. Advances in sample preparation and analytical techniques for lipidomics study of clinical samples. TrAC - Trends in Analytical Chemistry. Elsevier B.V., 2015, pp 1–18. doi:10.1016/j.trac.2014.10.010.
Rodrigues de Morais, D.; Eliete Laguila Visentainer, J.; Pereira dos Santos, L.; Matsushita, M.; Evelázio de Souza, N.; Vergílio Visentainer, J. Evaluation of lipid extraction and fatty acid composition of human plasma. Rev. Bras. Hematol. Hemoter. 2010, 32(6), 439–443.
Gonzàlez-Illàn, F.; Ojeda-Torres, G.; Dìaz-Vàzquez, L. M.; Rosario, O. Detection of Fatty Acid Ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and teetotalers using a methodology based on microwave-assisted extraction followed by solid-phase microextraction and gas chromatography-mass spectrometry. J. Anal. Toxicol 2011, 35, 232–237.
Khoomrung, S.; Chumnanpuen, P.; Jansa-Ard, S.; Staìšhlman, M.; Nookaew, I.; Borén, J.; et al. Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD. Analytical Chemistry 2013, 85(10), 4912–4919. doi:10.1021/ac3032405.
Teo, C. C.; Chong, W. P. K.; Ho, Y. S. Development and application of microwave-assisted extraction technique in biological sample preparation for small molecule analysis. Metabolomics. 2013, pp 1109–1128. doi:10.1007/s11306-013-0528-7.
Li, Y.; Sylvie Fabiano-Tixier, A.; Vian, A.; Chemat, F. Solvent-free microwave extraction of bioactive compounds provides a tool for green analytical chemistry. Trends in Analytical Chemistry 2013, 47, 1–11. doi:10.1016/j.trac.2013.02.007ï.
Yingngam, B. Modern solvent-free microwave extraction with essential oil optimization and structure-activity relationships. In Studies in Natural Products Chemistry; Elsevier B.V., 2023; Vol. 77, pp 365–420. doi:10.1016/B978-0-323-91294-5.00011-7.
Rodríguez Seoane, P.; Flórez-Fernández, N.; Conde Piñeiro, E.; Domínguez González, H. Microwave-Assisted Water Extraction. In Water Extraction of Bioactive Compounds: From Plants to Drug Development; Elsevier, 2017; pp 163–198. doi:10.1016/B978-0-12-809380-1.00006-1.
Flórez, N.; Conde, E.; Domínguez, H. Microwave assisted water extraction of plant compounds. Journal of Chemical Technology and Biotechnology 2015, 90(4), 590–607. doi:10.1002/jctb.4519.
Llaver, M.; Oviedo, M. N.; Fiorentini, E. F.; Quintas, P. Y.; Wuilloud, R. G. Analytical developments and applications of ionic liquids for environmental studies. Trends in Environmental Analytical Chemistry. Elsevier B.V., 2021. doi:10.1016/j.teac.2021.e00131.
Bystrzanowska, M.; Pena-Pereira, F.; Marcinkowski, Ł.; Tobiszewski, M. How green are ionic liquids? – A multicriteria decision analysis approach. Ecotoxicology and Environmental Safety 2019, 174, 455–458. doi:10.1016/j.ecoenv.2019.03.014.
Hoffmann, J.; Nüchter, M.; Ondruschka, B.; Wasserscheid, P. Ionic liquids and their heating behaviour during microwave irradiation - A state of the art report and challenge to assessment. Green Chemistry 2003, 5(3), 296–299. doi:10.1039/b212533a.
Aduloju, E. I.; Yahaya, N.; Mohammad Zain, N.; Anuar Kamaruddin, M.; Ariffuddin Abd Hamid, M. An Overview on the Use of DEEP Eutectic Solvents for Green Extraction of Some Selected Bioactive Compounds from Natural Matrices. Advanced Journal of Chemistry, Section A. Sami Publishing Company, 2023, pp 253–300. doi:10.22034/ajca.2023.389403.1356.
Hansen, B. B.; Spittle, S.; Chen, B.; Poe, D.; Zhang, Y.; Klein, J. M.; et al. Deep Eutectic Solvents: A Review of Fundamentals and Applications. Chemical Reviews. American Chemical Society, 2021, pp 1232–1285. doi:10.1021/acs.chemrev.0c00385.
Smith, E. L.; Abbott, A. P.; Ryder, K. S. Deep Eutectic Solvents (DESs) and Their Applications. Chemical Reviews. American Chemical Society, 2014, pp 11060–11082. doi:10.1021/cr300162p.
Prasad, K. N.; Hassan, F. A.; Yang, B.; Kong, K. W.; Ramanan, R. N.; Azlan, A.; et al. Response surface optimisation for the extraction of phenolic compounds and antioxidant capacities of underutilised Mangifera pajang Kosterm. peels. Food Chemistry 2011, 128(4), 1121–1127. doi:10.1016/j.foodchem.2011.03.105.
https://www.anton-paar.com/it-it/
https://cem.com/
https://www.milestonesrl.com/