human milk; infant formulas; evaluation model; phospholipids
Abstract :
[en] Human milk phospholipid (HMPL) plays an indispensable role in infant growth, while there are few studies focused on the comprehensive phospholipid composition between human milk and infant formula. In this study, LC-MS/MS and a similarity evaluation model were used to compare phospholipid composition from human milk and infant formula. The results showed that the number of phospholipid molecules detected in HM (137) was higher than that in CIFs (86) and GIFs (77). Furthermore, the similarity evaluation showed that although the average comprehensive similarity score for CIFs (65.68) was higher than that for GIFs (53.62), their phospholipid compositions Journal Pre-proof differed significantly from HMPLs. Therefore, these results not only deepen our understanding of Journal Pre-proof HM phospholipids but also provide a new scientific basis for the development of infant formulas.
Disciplines :
Agriculture & agronomy Chemistry
Author, co-author :
Zhu, Huiquan ; Université de Liège - ULiège > TERRA Research Centre ; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China
Fauconnier, Marie-Laure ; Université de Liège - ULiège > Département GxABT > Chemistry for Sustainable Food and Environmental Systems (CSFES)
Zhang, Hong; Wilmar (Shanghai) Biotechnology Research & Development Center Co., Ltd, Shanghai, China
Xu, Xuebing; Wilmar (Shanghai) Biotechnology Research & Development Center Co., Ltd, Shanghai, China
Guo, Ruihua; Wilmar (Shanghai) Biotechnology Research & Development Center Co., Ltd, Shanghai, China
Zhang, Shuwen; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China
Wang, Xiaodan; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China
Lv, Jiaping; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China
Pang, Xiaoyang; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China
Wang, Yunna; Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing, China
Language :
English
Title :
Comparative phospholipid profiling of human milk and infant formulas using LC-MS/MS and a multi-parameter similarity evaluation model
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