[en] The 2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-l-oxide (EMPO), an easily prepared pyrroline-Noxide has been tested as a free radical scavenger. Spin adducts of superoxide, hydroxyl radical, and other free radicals were characterized in phosphate buffer at pH 7.0 and 5.6. At pH 7 in phosphate buffer, the EMPO/O2 2• spin adduct was estimated to be about five times more persistent than its DMPO analogue. Furthermore, its decay does not produce the
EMPO/HO• adduct.
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