Editorial: Reviews in ethnopharmacology: 2023

Editorial on the Research Topic Reviews in Ethnopharmacology: 2023 Since centuries, natural products have long been used for the treatment and management of various diseases and disorders (Dubey and Singla, 2019; Singla et al., 2019a; Singla et al., 2023b). Natural products have been the goldmine of bioactive compounds that hold great significance clinically (Singla et al., 2019b; Wang et al., 2024). Considering the strong role of natural products in the field of drug discover, we have proposed the Research Topic "Reviews in Ethnopharmacology: 2023" in order to collate the literature in the field of ethnopharmacology. We have received a total of 65 manuscripts, out of which, 30 manuscripts have been successfully published in our Research Topic. A total of 232 authors have contributed in this Research Topic. This Research Topic has garnered significant attention from the readers and viewers, with 83K topic views, 56K article views, and 24K article downloads, as on 5th March, 2025. The study of Wang et al. proposed the combination therapy of Rehmannia glutinosa DC. and Lilium lancifolium Thunb. for the treatment and management of depression. This combination is also associated with the traditional Chinese medicine, Baihe Dihuang Decoction. Bioactive compounds from this combination reported to inhibit serotonin or 5hydroxytryptamine (5-HT) reuptake in various nerve endings and cell bodies, along with modulation of brain-derived neurotrophic factor (BDNF),Tyrosine kinase receptor B (TrkB), Neurotrophin P75 receptor (P75NRT), Phospholipase Cγ (PLCγ), Phosphatidylinositol 3 kinase (PI3K), Raf kinase (Raf), and other targeted genes for depression as described in this article. Orozco-Barocio et al. focused on the cancer prevention and treatment using phytochemicals derived from medicinal plants belonging to Cactaceae family. Opuntia genera is the most significant genera of this family. This article tends to give an overview on various genera of Cactaceae family and their therapeutic potential especially in relation to cancer. Rahman et al. focused on the bioactive metabolites derived from soybean and discussed their medicinal and pharmaceutical properties in their study. Among the valuable metabolites they have highlighted were genistein, phytic acid, dietary fibers, conjugated linoleic acid, pinitol,